phosphamidon

Summary

Summary: An organophosphate cholinesterase inhibitor that is used as an insecticide.

Top Publications

  1. Li A, Liu X, Kong J, Hu H, Sun L, Qian Z. Determination of organophosphorous pesticide phosphamidon in environmental water with luminol chemiluminescence detection. J AOAC Int. 2009;92:914-8 pubmed
    A novel chemiluminescence method has been developed for the determination of the organophosphorous pesticide phosphamidon in environmental water samples, based on the reaction of phosphamidon with luminol-H2O2 in an alkaline medium using ..
  2. Sharma A, Mehta A, Rathor N, Chalawadi Hanumantappa M, Khanna N, Bhattacharya S. Melatonin attenuates cognitive dysfunction and reduces neural oxidative stress induced by phosphamidon. Fundam Clin Pharmacol. 2013;27:146-51 pubmed publisher
    ..Organophosphate pesticides like phosphamidon (PHOS) have been shown to adversely affect memory and induce oxidative stress on both acute and chronic ..
  3. Tarbah F, Kardel B, Pier S, Temme O, Daldrup T. Acute poisoning with phosphamidon: determination of dimethyl phosphate (DMP) as a stable metabolite in a case of organophosphate insecticide intoxication. J Anal Toxicol. 2004;28:198-203 pubmed
    Many organophosphate pesticides (OP) such as phosphamidon are unstable in aqueous solutions and especially in blood in the presence of esterases...
  4. Mukherjee S, Mukherjee N, Saini P, Roy P, Babu S. Ginger extract ameliorates phosphamidon induced hepatotoxicity. Indian J Exp Biol. 2015;53:574-84 pubmed
    ..The present study enumerates the ameliorating effect of ginger extract (GE) against phosphamidon (PHO, an organophosphorus insecticide) induced hepatotoxicity...
  5. Cho H, Park J, Kim J, Han S, Choi Y. Multiresidue method for the quantitation of 20 pesticides in aquatic products. Anal Bioanal Chem. 2015;407:9043-52 pubmed publisher
    ..fluridone, hexaconazole, iprobenfos, malathion, methidathion, methiocarb, phenthoate, phosalone, phosmet, phosphamidon, pirimicarb, and simazine) in aquatic products...
  6. Ghosh C, Medda J. Ameliorating effects of thyroxine and atropine in phosphamidon intoxicated chick embryos. Biomed Environ Sci. 1999;12:34-42 pubmed
    The effects of thyroxine and atropine in ameliorating phosphamidon intoxication in chick embryos was studied...
  7. Kim S, Park M, Kim H, Shin J, Ko K, Kim D, et al. Analysis of Insecticides in Dead Wild Birds in Korea from 2010 to 2013. Bull Environ Contam Toxicol. 2016;96:25-30 pubmed publisher
    ..4% of the total samples analyzed. Monocrotophos and phosphamidon were the most common insecticides identified at rates of 50.0% and 30...
  8. Rashidi Nodeh H, Wan Ibrahim W, Kamboh M, Sanagi M. New magnetic graphene-based inorganic-organic sol-gel hybrid nanocomposite for simultaneous analysis of polar and non-polar organophosphorus pesticides from water samples using solid-phase extraction. Chemosphere. 2017;166:21-30 pubmed publisher
    ..MSPE was linear in the range 100-1000 pg mL-1 for phosphamidon and dimethoate, and 10-100 pg mL-1 for chlorpyrifos and diazinon, with limit of detection (S/N = ..
  9. Alizadeh A, Talebi Jahromi K, Hosseininaveh V, Ghadamyari M. Toxicological and biochemical characterizations of AChE in phosalone-susceptible and resistant populations of the common pistachio psyllid, Agonoscena pistaciae. J Insect Sci. 2014;14:18 pubmed publisher
    ..7-fold to monocrotophos and phosphamidon, respectively. Whereas, the insensitivity ratios for Rafsanjan population were 0.86, 0.8, 0.78, 0.46, and 0...

More Information

Publications71

  1. Zhou Q, Li J, Wang B, Wang S, Li H, Chen J. Selectivity improvement of positive photoionization ion mobility spectrometry for rapid detection of organophosphorus pesticides by switching dopant concentration. Talanta. 2018;176:247-252 pubmed publisher
    ..reactant ions (Ac)2H+, which were employed to ionize the OPPs including fenthion, imidan, phosphamidon, dursban, dimethoate and isocarbophos via the proton transfer reaction...
  2. Ben Ami H, Ben Haim S, Edoute Y, Hayam G, Taitelman U. Direct effects of phosphamidon on isolated working rat heart electrical and mechanical function. Toxicol Appl Pharmacol. 1991;110:429-34 pubmed
    b>Phosphamidon (2-chloro-3-(diethylamino)-1-methyl-3-oxopropanyldimethyl phosphate) is widely used in agriculture as an organophosphate insecticide. It is a water-soluble cholinesterase inhibitor whose estimated rat LD50 is 9.2 mg/kg, ip...
  3. Ortiz Hernández M, Quintero Ramírez R, Nava Ocampo A, Bello Ramírez A. Study of the mechanism of Flavobacterium sp. for hydrolyzing organophosphate pesticides. Fundam Clin Pharmacol. 2003;17:717-23 pubmed
    ..and theoretically studied: phorate, tetrachlorvinphos, methyl-parathion, terbufos, trichloronate, ethoprophos, phosphamidon, fenitrothion, dimethoate and DEF. The Flavobacterium sp...
  4. Naqvi S, Hasan M. Regional alterations in the monoamine levels, monoamine oxidase activity & neurobehavioural effects in rats treated with Dimecron (phosphamidon). Indian J Med Res. 1991;94:71-5 pubmed
    ..e., phosphamidon (2.0 mg/kg b wt, ip x 7 days). Open field behaviour (OFB) of the rats was examined thrice a day for seven days...
  5. Datta C, Gupta J, Sengupta D. Interaction of organophosphorus insecticides phosphamidon & malathion on lipid profile & acetylcholinesterase activity in human erythrocyte membrane. Indian J Med Res. 1994;100:87-9 pubmed
    The organophosphorus insecticides phosphamidon and malathion were found to inhibit the activity of human acetylcholinesterase in vitro, in the human erythrocyte membrane...
  6. Awal M, Malik J. The effect of long-term exposure to phosphamidon on the ruminal microorganisms and circulating carboxylesterase of Bubalus bubalis. Vet Res Commun. 1992;16:311-5 pubmed
    The effect of long-term exposure to the organophosphate insecticide phosphamidon on the ruminal microorganisms and serum carboxylesterase of buffalo calves was investigated. Oral administration of phosphamidon in doses of 0.25 and 0...
  7. Dhar G, Barat S, Dhar K. Influence of the organophosphorus insecticide phosphamidon on lentic water. J Environ Biol. 2004;25:359-63 pubmed
    ..Pesticides drained to the aquatic environment are primarily of agricultural origin. Phosphamidon (widely used organophosphate pesticide in paddy field) significantly reduced dissolved oxygen (DO) at 1...
  8. Naqvi S, Hasan M. Acetylhomocysteine thiolactone protection against phosphamidon-induced alteration of regional superoxide dismutase activity in the central nervous system and its correlation with altered lipid peroxidation. Indian J Exp Biol. 1992;30:850-2 pubmed
    b>Phosphamidon intoxication (2 mg/kg body wt./day for 7 days) inhibited SOD activity, but enhanced the lipid peroxidation in various CNS regions. Administration of cithiolone (8 mg/kg body wt...
  9. Khan P, Sinha S. Ameliorating effect of vitamin C on murine sperm toxicity induced by three pesticides (endosulfan, phosphamidon and mancozeb). Mutagenesis. 1996;11:33-6 pubmed
    ..changes in sperm count and sperm head morphology in mice fed either 3, 6 or 1000 mg/kg body wt/day endosulfan, phosphamidon or mancozeb, respectively...
  10. Ahmed T, Pathak R, Mustafa M, Kar R, Tripathi A, Ahmed R, et al. Ameliorating effect of N-acetylcysteine and curcumin on pesticide-induced oxidative DNA damage in human peripheral blood mononuclear cells. Environ Monit Assess. 2011;179:293-9 pubmed publisher
    Endosulfan, malathion, and phosphamidon are widely used pesticides. Subchronic exposure to these contaminants commonly affects the central nervous system, immune, gastrointestinal, renal, and reproductive system...
  11. Khan P, Sinha S. Impact of higher doses of vitamin C in modulating pesticide genotoxicity. Teratog Carcinog Mutagen. 1994;14:175-81 pubmed
    ..effect of higher doses of vitamin C (ascorbic acid) on the genotoxicity of the three pesticides (endosulfan, phosphamidon, and mancozeb) was assessed in the in vivo micronucleus test in Swiss albino mice...
  12. Ahmed T, Tripathi A, Ahmed R, Banerjee B. Assessment of phosphamidon-induced apoptosis in human peripheral blood mononuclear cells: protective effects of N-acetylcysteine and curcumin. J Biochem Mol Toxicol. 2010;24:286-92 pubmed publisher
    The molecular mechanism for noncholinergic toxicity of phosphamidon, an extensively used organophosphate pesticide, is still not clear...
  13. Joshi V, Arora T, Mehta A, Sharma A, Rathor N, Mehta K, et al. Effect of phosphamidon on convulsive behavior and biochemical parameters: modulation by progesterone and 4'-chlorodiazepam in rats. Naunyn Schmiedebergs Arch Pharmacol. 2010;382:311-20 pubmed publisher
    b>Phosphamidon (PHOS) has been shown to affect nervous system adversely...
  14. Akbarsha M, Sivasamy P. Apoptosis in male germinal line cells of rat in vivo: caused by phosphamidon. Cytobios. 1997;91:33-44 pubmed
    When Wistar strain male albino rats were fed on drinking water containing phosphamidon at 35 ppm concentration for 30 days, the spermatogenic compartment of the testis underwent histopathological changes...
  15. Rouvalis A, Karadima C, Zioris I, Sakkas V, Albanis T, Iliopoulou Georgudaki J. Determination of pesticides and toxic potency of rainwater samples in western Greece. Ecotoxicol Environ Saf. 2009;72:828-33 pubmed publisher
    ..The pesticide determination was conducted with GC-MS. Only phosphamidon was detected, which appeared in 52% and 13% of the rural and urban areas, respectively...
  16. Sahu C, Ghatak S. Effects of dimecron on developing chick embryo: malformations and other histopathological changes. Anat Histol Embryol. 2002;31:15-20 pubmed
    ..The liver and kidney were severely affected by the pesticide at both doses. Based upon these findings it may be concluded that dimecron does play a role in producing embryotoxicity at different stages of embryogenesis. ..
  17. Suke S, Ahmed R, Pathak R, Tripathi A, Banerjee B. Attenuation of phosphamidon-induced oxidative stress and immune dysfunction in rats treated with N-acetylcysteine. Braz J Med Biol Res. 2008;41:765-8 pubmed
    The effect of N-acetylcysteine, a thiolic antioxidant, on attenuation of phosphamidon-induced oxidative stress and immune dysfunction was evaluated in adult male Wistar rats weighing 200-250 g...
  18. Cicchetti R, Argentin G. The role of oxidative stress in the in vitro induction of micronuclei by pesticides in mouse lung fibroblasts. Mutagenesis. 2003;18:127-32 pubmed
    ..1 mg/ml) in defence against the genotoxicity of phosphamidon (80 microg/ml) and dieldrin (25 microM) was investigated in order to demonstrate that the two pesticides damage ..
  19. Nag M, Nandi N. Effect of three organophosphates on respiration in rat brain and liver tissue. Biosci Rep. 1991;11:7-10 pubmed
    The effects of three organophosphate pesticides, i.e. monocrotophos, dichlorvos, and phosphamidon on respiration in rat brain and liver tissue slices have been studied...
  20. Sharma A, Bhattacharya S, Khanna N, Tripathi A, Arora T, Mehta A, et al. Effect of progesterone on phosphamidon-induced impairment of memory and oxidative stress in rats. Hum Exp Toxicol. 2011;30:1626-34 pubmed publisher
    ..Organophosphorus pesticides like phosphamidon have been shown to adversely affect memory and induce oxidative stress on both acute and chronic exposure...
  21. Agarwal A, Sankaranarayanan A, Sharma P. Acute neurobehavioural toxicity of phosphamindon and its drug-induced alteration. Indian J Physiol Pharmacol. 1990;34:101-4 pubmed
    b>Phosphamidon, a systemic organophosphate insecticide, (1.4 mg/kg - dose 1/4th of LD50 given ip), produced several autonomic, neurological and behavioral effects in mice with peak effects being at 15 min...
  22. Khan P, Sinha S. Vitamin C mediated amelioration of pesticide genotoxicity in murine spermatocytes. Cytobios. 1994;80:199-204 pubmed
    The effect of vitamin C on the genotoxicity of three pesticides (Endosulfan, Phosphamidon, Mancozeb) was monitored by screening meiotic (metaphase I) chromosomes in the primary spermatocytes of Swiss albino mice, Mus musculus...
  23. Saxena S, Ashok B, Musarrat J. Mutagenic and genotoxic activities of four pesticides: captan, foltaf, phosphamidon and furadan. Biochem Mol Biol Int. 1997;41:1125-36 pubmed
    The mutagenic and genotoxic potential of four pesticides viz. captan, foltaf, phosphamidon and furadan was evaluated by the Ames mutagenicity assay and their DNA damaging ability on radiation repair defective E...
  24. Adhikari N, Grover I. Genotoxic effects of some systemic pesticides: in vivo chromosomal aberrations in bone marrow cells in rats. Environ Mol Mutagen. 1988;12:235-42 pubmed
    ..It was observed that 2,4-D, dimecron, and vitavax were clastogenic, but the results obtained with benomyl and monocrotophos were equivocal...
  25. Naqvi S, Hasan M. Phosphamidon neurotoxicity: protection by acetylhomocysteine thiolactone. Neuroreport. 1991;2:61-3 pubmed
    The present study was undertaken to evaluate the neurotoxic effects of the organophosphate, phosphamidon, on glutathione-S-transferase (GST) activity and concentration of sulphhydryl groups, and to study the possible protection against ..
  26. Subramani T, Chandrashekharaiah K, Swamy N, Murthy K. Purification and characterization of carboxylesterase from the seeds of Jatropha curcas. Protein J. 2012;31:120-8 pubmed publisher
    ..The enzyme was resistant towards carbamates (carbaryl and eserine sulfate) and sulphydryl inhibitors (p-chloromercuricbenzoate, PCMB) and inhibited by organophosphates (dichlorvos, parathion and phosphamidon).
  27. Abdelsalam E. Neurotoxic potential of six organophosphorus compounds in adult hens. Vet Hum Toxicol. 1999;41:290-2 pubmed
    The neurotoxic potential of trichlorfon, diazinon, phosmet, dichlorvos, phosphamidon and coumaphos was evaluated for their ability to inhibit brain neurotoxic esterase (NTE) activity in adult hens...
  28. Critter S, Airoldi C. Application of calorimetry to microbial biodegradation studies of agrochemicals in oxisols. J Environ Qual. 2001;30:954-9 pubmed
    ..was used to monitor the inhibitory effect caused by the bipyridynium diquaternary salts paraquat, diquat, and phosphamidon on microbial activity in a Red Latosol soil (Oxisol). The thermal effect was recorded on samples composed of 1...
  29. Reddy M, Rao K. Effects of sublethal concentrations of phosphamidon, methyl parathion, DDT, and lindane on tissue nitrogen metabolism in the penaeid prawn, Metapenaeus monoceros (Fabricius). Ecotoxicol Environ Saf. 1990;19:47-54 pubmed
    ..studied in a penaeid prawn, Metapenaeus monoceros, following its exposure to sublethal concentrations of phosphamidon, methyl parathion, DDT, and lindane...
  30. Soni I, Bhatnagar P. Embryotoxic and teratogenic studies of phosphamidon in Swiss albino mice. Teratog Carcinog Mutagen. 1989;9:253-7 pubmed
    b>Phosphamidon, an organophosphate pesticide, is little known for its possible effects on mammalian conceptus. The present investigation was carried out to evaluate its embryotoxic and teratogenic effects on Swiss albino mice...
  31. Reddy M, Rao K. Toxic impact of phosphamidon on acid phosphatase of prawn, Metapenaeus monoceros (Fabricius). Biochem Int. 1990;22:1025-31 pubmed
    ..of penaeid prawn, Metapenaeus monoceros were studied after exposure to selected sublethal concentrations of phosphamidon after acute and chronic exposure...
  32. Ben Haim S, Ben Ami H, Hayam G, Taitelman U, Edoute Y. Effect of phosphamidon and obidoxime on the QT-RR relationship of isolated rat heart. Pharmacol Toxicol. 1992;70:402-6 pubmed
    We studied the effects of phosphamidon (an organophosphate compound), obidoxime (a cholinesterase reactivator), and their combination, phosphamidon/obidoxime (PD/OB) on cardiac cycle length (RR), QT interval, and on QT-RR relationship of ..
  33. Jayaprada P, Reddy M, Rao K. Subacute physiological stress induced by phosphamidon on carbohydrate metabolism in midgut gland of prawn, Penaeus indicus. Biochem Int. 1991;23:507-14 pubmed
    ..metabolism of penaeid prawn, Penaeus indicus was studied on acute and acclimation to sublethal concentration of phosphamidon. The midgut gland tissue of acclimated prawn showed inhibited glycolysis with an onset of gluconeogenesis...
  34. Moser V. Age-related differences in acute neurotoxicity produced by mevinphos, monocrotophos, dicrotophos, and phosphamidon. Neurotoxicol Teratol. 2011;33:451-7 pubmed publisher
    ..blood cell (RBC) ChE measurements, along with motor activity, for mevinphos, monocrotophos, dicrotophos, and phosphamidon. Long-Evans hooded male rats were tested as adults and at postnatal day (PND) 17; PND11 pups were also tested ..
  35. Kosta P, Mehta A, Sharma A, Khanna N, Mediratta P, Mundhada D, et al. Effect of piracetam and vitamin E on phosphamidon-induced impairment of memory and oxidative stress in rats. Drug Chem Toxicol. 2013;36:48-54 pubmed publisher
    Organophosphate pesticides, such as phosphamidon (PHOS), have been shown to adversely affect memory and induce oxidative stress after both acute and chronic exposure...
  36. Thangavel P, Nivedhitha H, Ramaswamy M. Comparative study on individual and combined effects of dimecron and ziram on carbohydrate metabolites in liver, muscle, heart, and blood of a freshwater teleost, Sarotherodon mossambicus (Peters). Bull Environ Contam Toxicol. 2004;72:365-72 pubmed
  37. Naqvi S, Hasan M. Dose-related accumulation of organophosphate phosphamidon in discrete regions of the CNS: correlation with its neurotoxicity. Pharmacol Toxicol. 1990;67:47-8 pubmed
    b>Phosphamidon was detected by thin-layer chromatography (TLC) from various CNS regions of the rats intoxicated with three doses (1.0, 1.5 and 2.0 mg/kg body-weight) intraperitoneally daily for seven days...
  38. Bhatnagar P, Soni I. Evaluation of the teratogenic potential of phosphamidon in mice by gavage. Toxicol Lett. 1988;42:101-7 pubmed
    b>Phosphamidon, an organophosphate pesticide, is an established cholinesterase inhibitor...
  39. Zhuang J, Cheng Y, Yang S, Shu J, Levy L. The setting of an occupational exposure limit for phosphamidon in the workplace--a Chinese approach. Ann Occup Hyg. 1993;37:89-99 pubmed
    This paper describes the approach of setting an occupational exposure limit for phosphamidon, an organophosphorus pesticide, in the workplace in China...
  40. Tsatsakis A, Aguridakis P, Michalodimitrakis M, Tsakalov A, Alegakis A, Koumantakis E, et al. Experiences with acute organophosphate poisonings in Crete. Vet Hum Toxicol. 1996;38:101-7 pubmed
    ..8 micrograms fenthion/g, 0.8 micrograms methidathion/g) and uterus (170.5 micrograms malathion/g). Extracorporeal decontamination to enhance pesticide elimination is a therapeutic challenge. ..
  41. Anandkumar A, Tripathy A, Tripathy N. Effect of dimecron on the blood parameters of Heteropneustes fossilis. J Environ Biol. 2001;22:297-9 pubmed
    ..But, there was significant increase in the MCH and MCV values following both acute and chronic exposures. The results indicate possible induction of anaemia in the exposed fish. ..
  42. Gill T, Pande J, Tewari H. Individual and combined toxicity of common pesticides to teleost Puntius conchonius Hamilton. Indian J Exp Biol. 1991;29:145-8 pubmed
    Individual and combined toxicity of three pesticides, endosulfan, phosphamidon, and aldicarb was evaluated in P. conchonius. The 48 hr LC50 was 21.36 and 446.5 ppm respectively for endosulfan and phosphamidon...
  43. Akbarsha M, Sivasamy P. Male reproductive toxicity of phosphamidon: histopathological changes in epididymis. Indian J Exp Biol. 1998;36:34-8 pubmed
    b>Phosphamidon, a neurotoxic insecticide, was tested for male reproductive toxicity with special reference to the epididymis...
  44. Reddy M, Rao K. Phosphamidon, methylparathion and dichlorvos impact on tissue oxidative metabolism in penaeid prawn, Metapenaeus monoceros. Biochem Int. 1991;23:439-47 pubmed
    ..prawn, Metapenaeus monoceros was studied, following its exposure to selected organophosphorous insecticides phosphamidon, dichlorovos and methylparathion...
  45. Datta C, Gupta J, Sarkar A, Sengupta D. Effects of organophosphorus insecticide phosphomidon on antioxidant defence components of human erythrocyte and plasma. Indian J Exp Biol. 1992;30:65-7 pubmed
  46. Suke S, Shukla A, Mundhada D, Banerjee B, Mediratta P. Effect of phosphamidon on cognition and oxidative stress and its modulation by ascorbic acid and 4'-chlorodiazepam in rats. Pharmacol Biochem Behav. 2013;103:637-42 pubmed publisher
    ..The present study was designed to investigate the effect of 4'-chlorodiazepam (4CD) or ascorbic acid (Vit C) on phosphamidon (PM) induced modulation of cognitive function and oxidative stress in male Wistar rats...
  47. Reddy M, Rao K. Modulation of carbohydrate metabolism in the selected tissues of marine prawn, Penaeus indicus (H. Milne Edwards), under phosphamidon-induced stress. Ecotoxicol Environ Saf. 1988;15:212-20 pubmed
    ..3 ppm) of phosphamidon. A significant decrease in glycogen and pyruvate and an increase in lactate content were observed in all ..
  48. Cicchetti R, Bari M, Argentin G. Induction of micronuclei in bone marrow by two pesticides and their differentiation with CREST staining: an in vivo study in mice. Mutat Res. 1999;439:239-48 pubmed
    Two pesticides, organophosphate phosphamidon (PHO) and organochlorine dieldrin (DED) were assayed by the mouse bone marrow micronucleus test, to ascertain whether they showed genotoxic activity in vivo...
  49. Kuwar R, Jha C, Saxena A, Bhattacharya S. Effect of phosphamidon on the testes of albino rats: a histological study. Nepal Med Coll J. 2006;8:224-6 pubmed
    ..shows the qualitative and quantitative histological changes in testes of albino rats treated with two doses of phosphamidon 35 and 50 parts per million(ppm) for 1 month time period...
  50. Suke S, Ahmed R, Tripathi A, Chakraborti A, Banerjee B. Immunotoxicity of phosphamidon following subchronic exposure in albino rats. Indian J Exp Biol. 2006;44:316-20 pubmed
    Effect of subchronic doses of phosphamidon exposure on humoral and cell mediated immune (CMI) responses were studied in male albino rats using SRBC, ovalbumin and KLH as antigens...
  51. Thangavel P, Sumathiral K, Karthikeyan S, Ramaswamy M. Endocrine response of the freshwater teleost, Sarotherodon mossambicus (Peters) to dimecron exposure. Chemosphere. 2005;61:1083-92 pubmed
  52. Chuang C, Lin T, Tsai M. Delayed neuropathy and myelopathy after organophosphate intoxication. N Engl J Med. 2002;347:1119-21 pubmed
  53. Kwon Y, Wee S, Kim J. Pesticide poisoning events in wild birds in Korea from 1998 to 2002. J Wildl Dis. 2004;40:737-40 pubmed
    ..b>Phosphamidon was most frequently identified as the cause of poisoning, accounting for 23 mortality events...
  54. Kwon Y, Jeon W, Kang M, Kim J, Olsen G. Disseminated visceral coccidiosis in a wild white-naped crane (Grus vipio). J Wildl Dis. 2006;42:712-4 pubmed
    ..visceral coccidiosis (DVC) was unexpectedly recognized in a wild white-naped crane (Grus vipio) killed by phosphamidon insecticide...
  55. Khan P, Sinha S. Antimutagenic efficacy of higher doses of vitamin C. Mutat Res. 1993;298:157-61 pubmed
    Vitamin C, when administered concurrently with a pesticide (endosulfan, phosphamidon or mancozeb), could significantly decrease the frequency of pesticide-induced clastogenic and mitosis-disruptive changes in the bone marrow cells of ..
  56. Jokanovic M, Maksimovic M, Stepanović R. Interaction of phosphamidon with neuropathy target esterase and acetylcholinesterase of hen brain. Arch Toxicol. 1995;69:425-8 pubmed
    b>Phosphamidon (PSM) is an organophosphorus insecticide widely used in agriculture...
  57. Reddy M, Kodavanti P, Rao K. Toxic impact of phosphamidon on protein degradation in phasic and tonic muscles of marine prawn, Penaeus indicus (H. Milne Edwards). Arch Int Physiol Biochim. 1990;98:347-51 pubmed
    ..marine prawn, Penaeus indicus following acute (2 d) and chronic (15 d) exposure to sublethal concentration of phosphamidon. During exposure, greater decrease in sarcoplasmic protein fraction was observed in phasic muscle as compared ..
  58. Victoria Barahona M, Sánchez Fortún S. Protective effect induced by atropine, carbamates, and 2-pyridine aldoxime methoiodide Artemia salina larvae exposed to fonofos and phosphamidon. Ecotoxicol Environ Saf. 2007;66:65-73 pubmed
    The acute toxicity of fonofos and phosphamidon on three age classes of Artemia salina was evaluated. An increase in toxicity of these organophosphorous (OP) insecticides was found following longer development of A. salina...
  59. Awal M, Malik J, Sandhu H. Measurement by spectrophotometer of blood cholinesterases inactivation following single oral doses of phosphamidon in Bubalus bubalis. Vet Hum Toxicol. 1988;30:444-6 pubmed
    The effect of phosphamidon on blood cholinesterases (ChE) was investigated in male buffalo calves following single oral doses of 20, 40 and 80 mg/kg body wt...
  60. Tripathy N, Majhi B, Dey L, Patnaik K, Das C. Mutagenicity of dimecron studied in 3 mosaic assays and the sex-linked recessive lethal test in Drosophila melanogaster. Mutat Res. 1987;189:277-83 pubmed
    ..Dimecron is mutagenic to the somatic and germ line cells of Drosophila and induces a high frequency of sex-linked recessive lethals. ..
  61. Ben Haim S, Ben Ami H, Hayam G, Taitelman U, Edoute Y. Obidoxime augments the positive inotropic effect of phosphamidon on the isolated working rat heart. Pharmacol Toxicol. 1992;71:127-31 pubmed
    ..to determine modulation of the direct inotropic effect of an anticholinesterase organophosphorus compound, phosphamidon, by the reactivator obidoxime...
  62. Rabindranathan S, Devipriya S, Yesodharan S. Photocatalytic degradation of phosphamidon on semiconductor oxides. J Hazard Mater. 2003;102:217-29 pubmed
    The photocatalytic degradation of a small concentration of an organo-phosphorous (OP) insecticide phosphamidon, in water, on ZnO and TiO(2) is investigated...