monocrotophos

Summary

Summary: An organophosphate insecticide that inhibits monoamine oxidase and acetylcholinesterase. It has been shown to be genotoxic.

Top Publications

  1. Bhadbhade B, Sarnaik S, Kanekar P. Bioremediation of an industrial effluent containing monocrotophos. Curr Microbiol. 2002;45:346-9 pubmed
    ..In India, pesticide consumption for protecting crops is about 3% of the total world consumption. Monocrotophos (MCP), an organophosphorus insecticide, is widely used to control insects on crops...
  2. Johal M, Sharma M, Ravneet -. Impact of low dose of organophosphate, monocrotophos on the epithelial cells of gills of Cyprinus carpio communis Linn.--SEM study. J Environ Biol. 2007;28:663-7 pubmed
    ..upon exposure to 1/10th of LC50 of monocrotophos which is considered to be insignificant concentration from toxicological point of view...
  3. Janghel E, Rai J, Khan S, Rai M, Gupta V. TLC-spectrophometric separation and trace determination of monocrotophos and dichlorvos in enviromental and biological samples. J Environ Sci Eng. 2007;49:133-8 pubmed
    Organophosphorus insecticides, monocrotophos and dichlrovos are increasingly being used in agriculture to control insects on a wide range of crops...
  4. Das P, Shaik A, Jamil K. Genotoxicity induced by pesticide mixtures: in-vitro studies on human peripheral blood lymphocytes. Toxicol Ind Health. 2007;23:449-58 pubmed
    ..18, 5.76, and 7.5 microM for endosulfan, carbofuran, and monocrotophos, respectively. When combined in equimolar concentrations, the LC50 values for cytotoxicity were 0.7, 0...
  5. Ravneet -, Johal M, Sharma M. Three-dimensional study on the effect of organophosphate pesticide 'monocrotophos' on lens of fish and its recovery. Vet Ophthalmol. 2009;12:152-7 pubmed publisher
    ..038, 0.062 and 0.126 p.p.m.) of monocrotophos along with untreated controls for 30 days...
  6. Dwivedi N, Bhutia Y, Kumar V, Yadav P, Kushwaha P, Swarnkar H, et al. Effects of combined exposure to dichlorvos and monocrotophos on blood and brain biochemical variables in rats. Hum Exp Toxicol. 2010;29:121-9 pubmed publisher
    Dichlorvos (DDVP) and monocrotophos (MC) are systemic insecticides and known to produce cholinergic and non-cholinergic effects. Individual toxic effects of these chemicals are known but their combined effects have not been studied...
  7. Kazi A, Oommen A. The effect of acute severe monocrotophos poisoning on inhibition, expression and activity of acetylcholinesterase in different rat brain regions. Neurotoxicology. 2012;33:1284-90 pubmed publisher
    This study examined the acute effects of severe monocrotophos (MCP) poisoning on AChE inhibition, mRNA expression and recovery of acetylcholinesterase activity in different regions of the rat brain...
  8. Kashyap M, Singh A, Kumar V, Tripathi V, Srivastava R, Agrawal M, et al. Monocrotophos induced apoptosis in PC12 cells: role of xenobiotic metabolizing cytochrome P450s. PLoS ONE. 2011;6:e17757 pubmed publisher
    b>Monocrotophos (MCP) is a widely used organophosphate (OP) pesticide. We studied apoptotic changes and their correlation with expression of selected cytochrome P450s (CYPs) in PC12 cells exposed to MCP...
  9. Tian H, Ru S, Wang Z, Cai W, Wang W. Estrogenic effects of monocrotophos evaluated by vitellogenin mRNA and protein induction in male goldfish (Carassius auratus). Comp Biochem Physiol C Toxicol Pharmacol. 2009;150:231-6 pubmed publisher
    b>Monocrotophos (MCP) is listed as a Prior Informed Consent chemical, and it is still used extensively in developing countries. It has been seen that MCP shows high toxicity in fish and aquatic ecosystems...

More Information

Publications62

  1. Kashyap M, Singh A, Siddiqui M, Kumar V, Tripathi V, Khanna V, et al. Caspase cascade regulated mitochondria mediated apoptosis in monocrotophos exposed PC12 cells. Chem Res Toxicol. 2010;23:1663-72 pubmed publisher
    b>Monocrotophos (MCP) is a commonly used organophosphorus (OP) pesticide. We studied apoptotic changes in PC12 cells exposed to MCP...
  2. Ren X, Han Z, Wang Y. Mechanisms of monocrotophos resistance in cotton bollworm, Helicoverpa armigera (Hübner). Arch Insect Biochem Physiol. 2002;51:103-10 pubmed publisher
    ..was identified as a resistance mechanism by comparing biochemical analysis with a laboratory selected monocrotophos resistant cotton bollworm (RR: 200) and the susceptible strain...
  3. Shukla P, Kalidhass B, Shah A, Palaskar D. Preparation and characterization of microcapsules of water-soluble pesticide monocrotophos using polyurethane as carrier material. J Microencapsul. 2002;19:293-304 pubmed
    Microencapsulation of the water soluble pesticide monocrotophos (MCR), using polyurethane (PU) as the carrier polymer, has been developed using two types of steric stabilizers, namely PLMA macrodiol and PLMA-g-PEO graft copolymer...
  4. Ali S, Rajini P. Elicitation of dopaminergic features of Parkinson's disease in C. elegans by monocrotophos, an organophosphorous insecticide. CNS Neurol Disord Drug Targets. 2012;11:993-1000 pubmed
    ..In the present study, Caenorhabditis elegans was selected as the model organism to evaluate the potential of monocrotophos (MCP), an OPI, to elicit dopaminergic features of Parkinson's disease in terms of dopamine content, basic ..
  5. Kazi A, Oommen A. Monocrotophos induced oxidative damage associates with severe acetylcholinesterase inhibition in rat brain. Neurotoxicology. 2012;33:156-61 pubmed publisher
    ..Brains of rats subject to acute monocrotophos poisoning (0...
  6. Zhu X, Cai J, Yang J, Su Q, Gao Y. Films coated with molecular imprinted polymers for the selective stir bar sorption extraction of monocrotophos. J Chromatogr A. 2006;1131:37-44 pubmed
    ..a 180 microm film formed from a formic acid solution of nylon-6 polymer either nonimprinted or imprinted with monocrotophos. Time sorption profiles were measured for the extraction of monocrotophos from dichloromethane at the ..
  7. Zhang X, Tian H, Wang W, Ru S. Exposure to monocrotophos pesticide causes disruption of the hypothalamic-pituitary-thyroid axis in adult male goldfish (Carassius auratus). Gen Comp Endocrinol. 2013;193:158-66 pubmed publisher
    ..To elucidate the thyroid disruption effects of monocrotophos (MCP), an organophosphate pesticide, on male goldfish (Carassius auratus), thyroid follicle histology, plasma ..
  8. Tian H, Ru S, Bing X, Wang W. Effects of monocrotophos on the reproductive axis in the male goldfish (Carassius auratus): potential mechanisms underlying vitellogenin induction. Aquat Toxicol. 2010;98:67-73 pubmed publisher
    b>Monocrotophos (MCP) is a highly toxic organophosphorus pesticide that has been banned in many countries...
  9. Pain D, Gargi R, Cunningham A, Jones A, Prakash V. Mortality of globally threatened Sarus cranes Grus antigon from monocrotophos poisoning in India. Sci Total Environ. 2004;326:55-61 pubmed
    ..the field and the cranes' alimentary tract contents identified residues of the organophosphate insecticide monocrotophos. Monocrotophos concentrations of 0.8 and 1.8 ppm were found in wheat samples, and 0.2-0.74 ppm (x=0...
  10. Tian H, Ru S, Wang W, Bing X. Effects of monocrotophos on the reproductive axis in the female goldfish (Carassius auratus). Comp Biochem Physiol C Toxicol Pharmacol. 2010;152:107-13 pubmed publisher
    b>Monocrotophos (MCP) is a highly toxic organophosphorus pesticide...
  11. Saleha Banu B, Danadevi K, Rahman M, Ahuja Y, Kaiser J. Genotoxic effect of monocrotophos to sentinel species using comet assay. Food Chem Toxicol. 2001;39:361-6 pubmed
    b>Monocrotophos is the single largest selling agrochemical in India. Sensitive biomarkers to study the genotoxic effects caused by monocrotophos in aquatic organisms, especially fish, are lacking...
  12. Xu L, Tian H, Wang W, Ru S. Effects of monocrotophos pesticide on serotonin metabolism during early development in the sea urchin, Hemicentrotus pulcherrimus. Environ Toxicol Pharmacol. 2012;34:537-547 pubmed publisher
    ..To investigate the mechanism by which monocrotophos (MCP) pesticide disrupts the serotonergic nervous system, we evaluated its effects on serotonin metabolism...
  13. Mahboob M, Rahman M, Danadevi K, Banu B, Grover P. Detection of DNA damage in mouse peripheral blood leukocytes by the comet assay after oral administration of monocrotophos. Drug Chem Toxicol. 2002;25:65-74 pubmed
    The objective of this study was to determine if single/double strand DNA breaks could be induced by monocrotophos (organophosphorus pesticide) in mice in vivo using the comet assay. Mice were dosed orally with 0.046, 0.093, 0.186, 0...
  14. Majumder S, Das A. Phosphate-solubility and phosphatase activity in Gangetic alluvial soil as influenced by organophosphate insecticide residues. Ecotoxicol Environ Saf. 2016;126:56-61 pubmed publisher
    ..b>monocrotophos, profenophos, quinalphos and triazophos at their field application rates (0.75, 1.0, 0.5 and 0.6 kg a.i...
  15. Sunmonu T, Oloyede O. Performance and haematological indices in rats exposed to monocrotophos contamination. Hum Exp Toxicol. 2010;29:845-50 pubmed publisher
    b>Monocrotophos is an organophosphate pesticide used in agriculture to control insect pests...
  16. Sun X, Xia K, Liu B. Design of fluorescent self-assembled multilayers and interfacial sensing for organophosphorus pesticides. Talanta. 2008;76:747-51 pubmed publisher
    ..sensing conditions of the SAMs are optimized that allow linear fluorescence response for methylparathion and monocrotophos over 5.97 x 10(-7) to 3.51 x 10(-6)gL(-1) and 3.98 x 10(-6) to 3.47 x 10(-5)gL(-1), with detection limit of 6...
  17. Vismaya -, Rajini P. Exacerbation of intestinal brush border enzyme activities and oxidative stress in streptozotocin-induced diabetic rats by monocrotophos. Chem Biol Interact. 2014;211:11-9 pubmed publisher
    The present study was undertaken to investigate the potential of monocrotophos (MCP), one of the widely used broad spectrum systemic organophosphorus insecticides (OPI) in India, to alter small intestinal structure and function...
  18. Zayed S, Farghaly M, Mahdy F, Soliman S. Impact of repeated pesticide applications on the binding and release of methyl 14C-monocrotophos and U-ring labelled 14C-carbaryl to soil matrices under field conditions. J Environ Sci Health B. 2008;43:595-604 pubmed publisher
    The dissipation of (O-methyl-14C) monocrotophos and U-ring labelled 14C-carbaryl was monitored for over two years in absence and presence of other insecticides using in situ soil columns...
  19. Rao J, Swamy A, Yamin S. In vitro brain acetylcholinesterase response among three inbred strains of mice to monocrotophos. J Environ Sci Health B. 1991;26:449-58 pubmed
    The strain differences in the neurotoxic potential of monocrotophos (MCP) were assessed by determining the inhibition of brain acetylcholinesterase (AChE) in BALB/cAnN, DBA/2J and C57BL/6J in vitro...
  20. Kaur S, Dhanju C. Biochemical effects of some organophosphorus pesticides on the ovaries of albino rats. Indian J Physiol Pharmacol. 2005;49:148-52 pubmed
    An evaluation of the toxic effects of three organophosphates; monocrotophos, dimethoate and methyl parathion on female reproduction was made by biochemical estimations of cytoplasmic and membrance bound proteins, lipids, phospholipids ..
  21. Rao R, Kaliwal B. Monocrotophos induced dysfunction on estrous cycle and follicular development in mice. Ind Health. 2002;40:237-44 pubmed
    b>Monocrotophos a organophosphate pesticide was administered orally at doses of 1.6, 3.3, 6.6, 10 and 13 mg/kg body weight/day to normal virgin Swiss albino mice for 30 days...
  22. Rao J, Kavitha P. Toxicity of azodrin on the morphology and acetylcholinesterase activity of the earthworm Eisenia foetida. Environ Res. 2004;96:323-7 pubmed
    The acute toxicity of azodrin (monocrotophos, an organophosphorus insecticide) was determined on a soil organism, Eisenia foetida...
  23. Gundi V, Viswanath B, Chandra M, Kumar V, Reddy B. Activities of cellulase and amylase in soils as influenced by insecticide interactions. Ecotoxicol Environ Saf. 2007;68:278-85 pubmed
    Interaction effects of the insecticides monocrotophos and quinalphos (organophosphates), and cypermethrin (pyrethroid), on microbial activities in two agricultural soils-black vertisol soil and red alfinsol soil were tested for 30 days ..
  24. Hayama T, Yoshida H, Todoroki K, Nohta H, Yamaguchi M. Determination of polar organophosphorus pesticides in water samples by hydrophilic interaction liquid chromatography with tandem mass spectrometry. Rapid Commun Mass Spectrom. 2008;22:2203-10 pubmed publisher
    ..was developed for the determination of polar organophosphorus pesticides (OPPs; acephate, methamidophos, monocrotophos, omethoate, oxydemeton-methyl, and vamidothion) in water samples...
  25. Leelaja B, Rajini P. Biochemical and physiological responses in Caenorhabditis elegans exposed to sublethal concentrations of the organophosphorus insecticide, monocrotophos. Ecotoxicol Environ Saf. 2013;94:8-13 pubmed publisher
    ..Our findings on C. elegans provide an easy diagnosis for OPI contamination and may become helpful in evaluating the ecotoxicological effects of OPI in the aquatic environment near agricultural fields. ..
  26. Santhakumar M, Balaji M, Ramudu K. Gill lesions in the perch, Anabas testudineus, exposed to monocrotophos. J Environ Biol. 2001;22:87-90 pubmed
    Histopathological effects of sublethal doses of monocrotophos on the gills have been studied by exposing the fish for a period ranging from ten to twenty days...
  27. Rao J, Begum G, Sridhar V, Reddy N. Sublethal effects of monocrotophos on locomotor behavior and gill architecture of the mosquito fish, Gambusia affinis. J Environ Sci Health B. 2005;40:813-25 pubmed
    Subacute studies of monocrotophos [Dimethyl (E)-1-methyl-2-(methyl-carbamoyl) vinyl phosphate] on mosquito fish, Gambusia affinis, were carried out in vivo for 24 days to assess the locomotor behavior, structural integrity of gill, and ..
  28. Belsey N, Cordery S, Bunge A, Guy R. Assessment of dermal exposure to pesticide residues during re-entry. Environ Sci Technol. 2011;45:4609-15 pubmed publisher
    ..a wide range of physicochemical properties: atrazine, 2,4-dichlorophenoxyacetic acid (2,4-D), chlorpyrifos, monocrotophos, and acetochlor...
  29. Mahboob M, Siddiqui M. Long-term effects of a novel phosphorothionate (RPR-II) on detoxifying enzymes in brain, lung, and kidney rats. Ecotoxicol Environ Saf. 2002;53:355-60 pubmed
    ..The present subacute study suggests that RPR-II may bring about physiological upsets by altering GSH- and GST-dependent events in different tissues of exposed organisms. ..
  30. Li F, Han Z. Mutations in acetylcholinesterase associated with insecticide resistance in the cotton aphid, Aphis gossypii Glover. Insect Biochem Mol Biol. 2004;34:397-405 pubmed
    ..Both subgroups contain resistance-associated AChE genes. To avoid confusion in the future work, a nomenclature of insect AChE is also suggested in the paper. ..
  31. Dwivedi N, Flora S. Concomitant exposure to arsenic and organophosphates on tissue oxidative stress in rats. Food Chem Toxicol. 2011;49:1152-9 pubmed publisher
    ..The present study examines the effects of dichlorvos (DDVP) or monocrotophos (MCP) and sodium meta arsenite, individually or in combination for 16 weeks on variables indicative of ..
  32. Sun L, Zhu S, Yang Z, Chen Q, Liu H, Zhang J, et al. Degradation of monocrotophos by Starkeya novella YW6 isolated from paddy soil. Environ Sci Pollut Res Int. 2016;23:3727-35 pubmed publisher
    A bacteria strain, YW6, capable of utilizing monocrotophos (MCP) as the sole carbon and nitrogen sources for growth was isolated from paddy soil and identified as Starkeya novella. Strain YW6 completely degraded 0...
  33. Peter J, Thomas L, Graham P, Moran J, Abhilash K, Jasmine S, et al. Performance of clinical scoring systems in acute organophosphate poisoning. Clin Toxicol (Phila). 2013;51:850-4 pubmed publisher
    ..93, n = 46) and chlorpyrifos (0.86, n = 38) and lowest in monocrotophos (0.60, n = 63)...
  34. Mahboob M, Siddiqui M, Jamil K. Subacute effects of a phosphorothionate pesticide on mixed function oxidases of Wistar rats. J Environ Sci Health B. 2000;35:739-49 pubmed
    ..Kidney and brain cyt.b5 activity decreased significantly at 90th day due to medium dose. Low dose also caused inhibition in cyt.b5 activity in brain at 90th day. Cytochrome P-450 reductase activity was decreased significantly in liver, ..
  35. Mahboob M, Siddiqui M. Alterations in hepatic detoxifying enzymes induced by new organophosphorus insecticides following subchronic exposure in rats. J Appl Toxicol. 2001;21:501-5 pubmed
    ..The results indicated that the two insecticides had different potential to modulate hepatic GST, UDPGT and GSH due to subchronic exposure and that these metabolic alterations are quite reversible after withdrawal of treatment. ..
  36. Rahman M, Mahboob M, Grover P. In vitro acetylcholinesterase inhibition by novel OP compounds in various tissues of the fish Channa punctatus. Bull Environ Contam Toxicol. 2004;72:38-44 pubmed
  37. Garg U, Pal A, Jha G, Jadhao S. Pathophysiological effects of chronic toxicity with synthetic pyrethroid, organophosphate and chlorinated pesticides on bone health of broiler chicks. Toxicol Pathol. 2004;32:364-9 pubmed
    ..experiment evaluated effects following chronic toxicity with 20 ppm fenvalerate (synthetic pyrethroid), 2 ppm monocrotophos (organophosphate) and 2 ppm endosulfan (chlorinated hydrocarbon) on bone health of broiler chicks...
  38. Yang Y, Yang Y, Gao W, Guo J, Wu Y, Wu Y. Introgression of a disrupted cadherin gene enables susceptible Helicoverpa armigera to obtain resistance to Bacillus thuringiensis toxin Cry1Ac. Bull Entomol Res. 2009;99:175-81 pubmed publisher
    ..The toxicity of two chemical insecticides, fenvalerate and monocrotophos, against the SCD-r1 strain was not significantly different from that to the SCD strain...
  39. Rahman M, Siddiqui M. Hematological and clinical chemistry changes induced by subchronic dosing of a novel phosphorothionate (RPR-V) in Wistar male and female rats. Drug Chem Toxicol. 2006;29:95-110 pubmed
    ..Alterations in these parameters show toxic stress in the treated animals especially on blood and blood-forming organs. ..
  40. Venkateswara Rao J. Sublethal effects of an organophosphorus insecticide (RPR-II) on biochemical parameters of tilapia, Oreochromis mossambicus. Comp Biochem Physiol C Toxicol Pharmacol. 2006;143:492-8 pubmed
    ..These results revealed that the OP insecticide RPR-II is highly toxic and affects the intermediary metabolism of O. mossambicus. ..
  41. Das Gupta R, Chakravorty P, Kaviraj A. Studies on relative toxicities of six insecticides on epigeic earthworm, Perionyx excavatus. Bull Environ Contam Toxicol. 2010;85:83-6 pubmed publisher
    ..03 mg/kg), carbaryl (LC(50)-6.07 mg/kg), chlorpyrifos (LC(50)-7.3 mg/kg), aldicarb (LC(50)-10.63 mg/kg) and monocrotophos (LC(50)-13.04 mg/kg)...
  42. Agrahari S, Gopal K, Pandey K. Biomarkers of monocrotophos in a freshwater fish Channa punctatus (Bloch). J Environ Biol. 2006;27:453-7 pubmed
    Activity of a few biomarkers have been investigated on freshwater fish Channa punctatus treated with monocrotophos for acute exposure to 18.56 ppm at 96 hr and subacute exposure viz. 0.46 ppm, 0.96 ppm and 1.86 ppm for 30 days...
  43. Kwon D, Choi J, Je Y, Lee S. The overexpression of acetylcholinesterase compensates for the reduced catalytic activity caused by resistance-conferring mutations in Tetranychus urticae. Insect Biochem Mol Biol. 2012;42:212-9 pubmed publisher
    ..G228S, A391T and F439W) and duplication of the acetylcholinesterase (AChE) gene (Tuace) are involved in monocrotophos resistance in the two-spotted spider mites, Tetranychus urticae (Kwon et al., 2010a, b)...
  44. Ali D, Kumar S. Long-term genotoxic effect of monocrotophos in different tissues of freshwater fish Channa punctatus (Bloch) using alkaline single cell gel electrophoresis. Sci Total Environ. 2008;405:345-50 pubmed publisher
    b>Monocrotophos, commonly known as azodrin, is one of the organophosphate pesticides extensively used in agricultural practices throughout the world...
  45. Patel A, Dewan A, Kaji B. Monocrotophos poisoning through contaminated millet flour. Arh Hig Rada Toksikol. 2012;63:377-83 pubmed publisher
    ..This report describes an episode of mass monocrotophos poisoning that occurred due to accidental ingestion of monocrotophos-contaminated millet (so-called bavta) ..
  46. Siddiqui M, Rahman M, Mahboob M, Anjum F, Mustafa M. Species differences in brain acetylcholinesterase and neuropathic target esterase response to monocrotophos. J Environ Sci Health B. 1988;23:291-9 pubmed
    The species differences in the neurotoxic and delayed neurotoxic potential of monocrotophos (MCP) were assessed by determining the in vitro inhibition of brain Acetylcholinesterase (AChE) and Neuropathic target esterase (NTE) in rat, ..
  47. Ku Y, Wang W, Shen Y. Reaction behaviors of decomposition of monocrotophos in aqueous solution by UV and UV/O processes. J Hazard Mater. 2000;72:25-37 pubmed
    The decomposition of monocrotophos (cis-3-dimethoxyphosphinyloxy-N-methyl-crotonamide) in aqueous solution by UV and UV/O(3) processes was studied...
  48. Jain R, Garg V. Enzymatic degradation of monocrotophos by extracellular fungal OP hydrolases. Appl Biochem Biotechnol. 2013;171:1473-86 pubmed publisher
    ..study explores the potential of extracellular fungal organophosphate (OP) hydrolase for the degradation of monocrotophos. Extracellular OP hydrolases were isolated and purified from five different fungal isolates viz...
  49. Laabs V, Amelung W, Pinto A, Altstaedt A, Zech W. Leaching and degradation of corn and soybean pesticides in an Oxisol of the Brazilian Cerrados. Chemosphere. 2000;41:1441-9 pubmed
    ..This order of the pesticides was also achieved by ranking them according to their effective sorption coefficient Ke, which is the ratio of Koc to field-dissipation half-life. ..
  50. Kashyap M, Singh A, Kumar V, Yadav D, Khan F, Jahan S, et al. Pkb/Akt1 mediates Wnt/GSK3?/?-catenin signaling-induced apoptosis in human cord blood stem cells exposed to organophosphate pesticide monocrotophos. Stem Cells Dev. 2013;22:224-38 pubmed publisher
    ..on related cell signaling were investigated in human umbilical cord blood stem cells (hUCBSCs) exposed to monocrotophos (MCP, an organophosphate pesticide)...
  51. Gupta R, Chakravorty P, Kaviraj A. Susceptibility of epigeic earthworm Eisenia fetida to agricultural application of six insecticides. Chemosphere. 2011;84:724-6 pubmed publisher
    ..The organophosphate insecticides chlorpyrifos (LC(50) - 28.58 mg kg(-1)), and monocrotophos (LC(50) - 39...
  52. Venkatesh S, Ramachandran A, Zachariah A, Oommen A. Mitochondrial ATP synthase inhibition and nitric oxide are involved in muscle weakness that occurs in acute exposure of rats to monocrotophos. Toxicol Mech Methods. 2009;19:239-45 pubmed publisher
    ..8LD(50)) dose of monocrotophos. Muscle mitochondrial ATP synthase activity was inhibited in the rat in acute exposure to monocrotophos while ..
  53. Sangeeta -, Handa S, Mittal P. SEM study on cytotoxic effect of monocrotophos (MCP) on lungs of rat. Indian J Exp Biol. 2002;40:835-8 pubmed
    b>Monocrotophos (MCP) on oral administration (0.28 mg/100 g of body wt. i.e...