sucralfate

Summary

Summary: A basic aluminum complex of sulfated sucrose.

Top Publications

  1. Nagy L, Nagata M, Szabo S. Protein and non-protein sulfhydryls and disulfides in gastric mucosa and liver after gastrotoxic chemicals and sucralfate: possible new targets of pharmacologic agents. World J Gastroenterol. 2007;13:2053-60 pubmed
    ..in chemically induced gastric hemorrhagic mucosal lesions (HML) and the mechanism of gastroprotective effect of sucralfate. Rats were given 1 mL of 75% ethanol, 25% NaCl, 0.6 mol/L HCl, 0...
  2. Maiche A, Isokangas O, Grohn P. Skin protection by sucralfate cream during electron beam therapy. Acta Oncol. 1994;33:201-3 pubmed
    ..There are no drugs available for the skin care. Sucralfate, a widely used anti-ulcer drug, has anti-inflammatory properties, and it activates cell proliferation...
  3. Calissendorff J, Gustafsson T, Holst J, Brismar K, Röjdmark S. Alcohol intake and its effect on some appetite-regulating hormones in man: influence of gastroprotection with sucralfate. Endocr Res. 2012;37:154-62 pubmed publisher
    ..We studied whether alcohol ingestion affects serum levels of these peripheral hormones, and if gastroprotective sucralfate prevents such an effect. Ten participants were investigated on four occasions...
  4. Hemstreet B. Use of sucralfate in renal failure. Ann Pharmacother. 2001;35:360-4 pubmed
    ..development of aluminum toxicity in patients with renal insufficiency or chronic renal failure who are taking sucralfate. Clinical literature accessed through MEDLINE (1966-December 1999) and International Pharmaceutical Abstracts (..
  5. Yildizdas D, Yapicioglu H, Yilmaz H. Occurrence of ventilator-associated pneumonia in mechanically ventilated pediatric intensive care patients during stress ulcer prophylaxis with sucralfate, ranitidine, and omeprazole. J Crit Care. 2002;17:240-5 pubmed
    The purpose of the study was to evaluate the effects of sucralfate, ranitidine, and omeprazole use on incidence of ventilatory-associated pneumonia (VAP) and mortality in ventilated pediatric critical care patients...
  6. Darlong V, Jayalakhsmi T, Kaul H, Tandon R. Stress ulcer prophylaxis in patients on ventilator. Trop Gastroenterol. 2003;24:124-8 pubmed
    The objective of the study was to assess the efficacy of the H2-receptor antagonists and sucralfate for the prophylaxis of stress ulcer in patients on a ventilator in an intensive care unit in the general intensive care unit of our ..
  7. Wells M, Macmillan M, Raab G, MacBride S, Bell N, MacKinnon K, et al. Does aqueous or sucralfate cream affect the severity of erythematous radiation skin reactions? A randomised controlled trial. Radiother Oncol. 2004;73:153-62 pubmed
    ..The purpose of this study was to investigate whether sucralfate or aqueous cream reduced acute skin toxicity during radiotherapy to the head and neck, breast or anorectal area (..
  8. Eamlamnam K, Patumraj S, Visedopas N, Thong Ngam D. Effects of Aloe vera and sucralfate on gastric microcirculatory changes, cytokine levels and gastric ulcer healing in rats. World J Gastroenterol. 2006;12:2034-9 pubmed
    To compare the effects of Aloe vera and sucralfate on gastric microcirculatory changes, cytokine levels and gastric ulcer healing. Male Spraque-Dawley rats (n=48) were divided into four groups...
  9. Du Y, Li Z, Zhan X, Chen J, Gao J, Gong Y, et al. Anti-inflammatory effects of rebamipide according to Helicobacter pylori status in patients with chronic erosive gastritis: a randomized sucralfate-controlled multicenter trial in China-STARS study. Dig Dis Sci. 2008;53:2886-95 pubmed publisher
    ..endogenous prostaglandin, and mucosal oxygen free radicals in chronic erosive gastritis (CEG) patients by using sucralfate as a control...

More Information

Publications62

  1. Brunner R, Wallmann J, Szalai K, Karagiannis P, Altmeppen H, Riemer A, et al. Aluminium per se and in the anti-acid drug sucralfate promotes sensitization via the oral route. Allergy. 2009;64:890-7 pubmed publisher
    ..It is also contained in anti-acid drugs like sucralfate (SUC). These anti-acids have been shown to cause sensitization to food proteins via elevation of the gastric pH...
  2. Zodpe P, Cho J, Kang H, Hwang S, Lee H. Efficacy of sucralfate in the postoperative management of uvulopalatopharyngoplasty: a double-blind, randomized, controlled study. Arch Otolaryngol Head Neck Surg. 2006;132:1082-5 pubmed
    To evaluate the effectiveness of sucralfate in influencing throat pain, otalgia, analgesic requirement, bleeding, mucosal recovery, and incidence of postoperative bleeding in patients undergoing uvulopalatopharyngoplasty...
  3. Allen A, Bygate E, Faessel H, Isaac L, Lewis A. The effect of ferrous sulphate and sucralfate on the bioavailability of oral gemifloxacin in healthy volunteers. Int J Antimicrob Agents. 2000;15:283-9 pubmed
    b>Sucralfate is a cytoprotectant with antacid properties and ferrous sulphate is commonly prescribed for iron-deficiency anaemia...
  4. Lo G, Lai K, Cheng J, Chen M, Huang H, Hsu P, et al. Endoscopic variceal ligation plus nadolol and sucralfate compared with ligation alone for the prevention of variceal rebleeding: a prospective, randomized trial. Hepatology. 2000;32:461-5 pubmed
    ..b>Sucralfate is a mucosal protector...
  5. Messori A, Trippoli S, Vaiani M, Gorini M, Corrado A. Bleeding and pneumonia in intensive care patients given ranitidine and sucralfate for prevention of stress ulcer: meta-analysis of randomised controlled trials. BMJ. 2000;321:1103-6 pubmed
    To determine the effectiveness of ranitidine and sucralfate in the prevention of stress ulcer in critical patients and to assess if these treatments affect the risk of nosocomial pneumonia...
  6. Dodd M, Miaskowski C, Greenspan D, MacPhail L, Shih A, Shiba G, et al. Radiation-induced mucositis: a randomized clinical trial of micronized sucralfate versus salt & soda mouthwashes. Cancer Invest. 2003;21:21-33 pubmed
    ..The clinical efficacy of sucralfate (Carafate R) mouthwash for head and neck cancer patients (HNC) is not consistent across studies...
  7. Hung C, Cheng J, Neu S. Prophylactic effects of sucralfate and geraniin on ethanol-induced gastric mucosal damage in rats. Chin J Physiol. 1995;38:211-7 pubmed
    The aim is to study the protective effects of topical sucralfate and geraniin on acidified ethanol (EtOH dissolved in 100 mM HCI plus 54 mM NaCl)-induced gastric acid back-diffusion, mucus production and mucosal ulcerations in the rat...
  8. O Brien P, Franklin C, Poulsen M, Joseph D, Spry N, Denham J. Acute symptoms, not rectally administered sucralfate, predict for late radiation proctitis: longer term follow-up of a phase III trial--Trans-Tasman Radiation Oncology Group. Int J Radiat Oncol Biol Phys. 2002;54:442-9 pubmed
    To assess the potential for sucralfate administered rectally to reduce the risk of late rectal morbidity in patients undergoing nonconformal radiotherapy (RT) for carcinoma of the prostate and to study the variables potentially ..
  9. Takabayashi F, Harada N, Yamada M, Murohisa B, Oguni I. Inhibitory effect of green tea catechins in combination with sucralfate on Helicobacter pylori infection in Mongolian gerbils. J Gastroenterol. 2004;39:61-3 pubmed
    ..Solutions of GTCs and solutions of GTCs adsorbed to sucralfate (GTC-scf), at concentrations of 20 mg GTCs and/or 20 mg sucralfate/ml were prepared...
  10. Sanguineti G, Franzone P, Marcenaro M, Foppiano F, Vitale V. Sucralfate versus mesalazine versus hydrocortisone in the prevention of acute radiation proctitis during conformal radiotherapy for prostate carcinoma. A randomized study. Strahlenther Onkol. 2003;179:464-70 pubmed
    To assess whether the topical use of steroids or 5-aminosalicylic acid (5-ASA) is superior to sucralfate in preventing acute rectal toxicity during three-dimensional conformal radiotherapy (3DCRT) to 76 Gy...
  11. Sencan A, Yilmaz O, Ozer E, Gunsar C, Genc K, Ulukus C, et al. Does sucralfate prevent apoptosis occurring in the ischemia/reperfusion-induced intestinal injury?. Eur J Pediatr Surg. 2003;13:231-5 pubmed
    We have shown in a previous study that sucralfate is beneficial in the prophylaxis and treatment of hypoxia/reoxygenation-induced intestinal injury...
  12. Saunders D, Epstein J, Elad S, Allemano J, Bossi P, van de Wetering M, et al. Systematic review of antimicrobials, mucosal coating agents, anesthetics, and analgesics for the management of oral mucositis in cancer patients. Support Care Cancer. 2013;21:3191-207 pubmed publisher
    ..Recommendations were developed against the use of the mucosal coating agent sucralfate for the prevention or treatment of chemotherapy-induced or radiation-induced OM...
  13. Misra U, Kalita J, Pandey S, Mandal S, Srivastava M. A randomized placebo controlled trial of ranitidine versus sucralfate in patients with spontaneous intracerebral hemorrhage for prevention of gastric hemorrhage. J Neurol Sci. 2005;239:5-10 pubmed
    ..stress ulcer prophylaxis in intracerebral hemorrhage (ICH), we have evaluated the usefulness of ranitidine and sucralfate in preventing gastric hemorrhage (GH) in patients with ICH...
  14. Matsuu Matsuyama M, Shichijo K, Okaichi K, Ishii K, Wen C, Fukuda E, et al. Sucralfate protects intestinal epithelial cells from radiation-induced apoptosis in rats. J Radiat Res. 2006;47:1-8 pubmed
    ..It has been reported that sucralfate treatment has a protective effect against ARC, though the mechanisms of action are unknown...
  15. Kantorova I, Svoboda P, Scheer P, Doubek J, Rehorkova D, Bosakova H, et al. Stress ulcer prophylaxis in critically ill patients: a randomized controlled trial. Hepatogastroenterology. 2004;51:757-61 pubmed
    ..v. once daily, n=72; H2 antagonists--famotidine 40 mg twice a day, n=71; and sucralfate 1 g every 6 hours, n=69) with placebo (n=75) in patients with trauma or after major surgery...
  16. Wada K, Kamisaki Y, Kitano M, Kishimoto Y, Nakamoto K, Itoh T. Effects of sucralfate on acute gastric mucosal injury and gastric ulcer induced by ischemia-reperfusion in rats. Pharmacology. 1997;54:57-63 pubmed
    ..In the present studies, we examined the effects of oral administration of sucralfate on gastric damage induced by I-R...
  17. Santarelli L, Gabrielli M, Candelli M, Cremonini F, Nista E, Cammarota G, et al. Post-cholecystectomy alkaline reactive gastritis: a randomized trial comparing sucralfate versus rabeprazole or no treatment. Eur J Gastroenterol Hepatol. 2003;15:975-9 pubmed
    ..The aim of this study was to assess the effect of sucralfate versus rabeprazole or no treatment on dyspeptic symptoms and endoscopic/histological signs in a population of ..
  18. Sonvico F, Colombo G, Gallina L, Bortolotti F, Rossi A, McInnes C, et al. Therapeutic paint of cidofovir/sucralfate gel combination topically administered by spraying for treatment of orf virus infections. AAPS J. 2009;11:242-9 pubmed publisher
    The aim of the research was to study a new cidofovir/sucralfate drug product to be used as a spray for treating the mucosal and/or skin lesions. The product, i.e...
  19. Dehghani S, Haghighat M, Imanieh M, Geramizadeh B. Solitary rectal ulcer syndrome in children: a prospective study of cases from southern Iran. Eur J Gastroenterol Hepatol. 2008;20:93-5 pubmed publisher
    ..All cases were treated initially with sucralfate enema and followed up. Nine boys and three girls were studied. The mean age of patients was 9.25+/-2.67 years...
  20. Alpsoy E, Er H, Durusoy C, Yilmaz E. The use of sucralfate suspension in the treatment of oral and genital ulceration of Behçet disease: a randomized, placebo-controlled, double-blind study. Arch Dermatol. 1999;135:529-32 pubmed
    To determine the efficacy of topically applied sucralfate suspension in the treatment of oral and genital ulceration of Behçet disease. A randomized, placebo-controlled, double-blind study at a university referral center...
  21. Bornstain C, Azoulay E, De Lassence A, Cohen Y, Costa M, Mourvillier B, et al. Sedation, sucralfate, and antibiotic use are potential means for protection against early-onset ventilator-associated pneumonia. Clin Infect Dis. 2004;38:1401-8 pubmed
    ..12 per point; 95% CI, 1.02-1.23), unplanned extubation (OR, 3.19; 95% CI, 1.28-7.92), and sucralfate use (OR, 1.81; 95% CI, 1.01-3.26). Protection occurred with use of aminoglycosides (OR, 0.36; 95% CI, 0.17-0...
  22. Jainu M, Devi C. Effect of Cissus quadrangularis on gastric mucosal defensive factors in experimentally induced gastric ulcer-a comparative study with sucralfate. J Med Food. 2004;7:372-6 pubmed
    ..quadrangularis (CQE) was comparable to that of the reference drug sucralfate. Further, gastric juice and mucosal studies showed that CQE at a dose of 500 mg/kg given for 10 days ..
  23. Dobrozsi D, Smith R, Sakr A. Comparative mucoretention of sucralfate suspensions in an everted rat esophagus model. Int J Pharm. 1999;189:81-9 pubmed
    ..esophageal mucoadhesive properties of viscous liquid formulations, and the model was applied to compare marketed sucralfate suspensions (Gastrogel, Antepsin, and Ulcogant) to better understand differences in clinical performance...
  24. Hovdenak N, Sørbye H, Dahl O. Sucralfate does not ameliorate acute radiation proctitis: randomised study and meta-analysis. Clin Oncol (R Coll Radiol). 2005;17:485-91 pubmed
    ..Prophylaxis during radiotherapy should ideally prevent acute reaction and the development of delayed injury. Sucralfate, an aluminium sucrose octasulphate, has been used for acute and delayed radiation side-effects...
  25. Moayyedi P, Soo S, Deeks J, Forman D, Harris A, Innes M, et al. Systematic review: Antacids, H2-receptor antagonists, prokinetics, bismuth and sucralfate therapy for non-ulcer dyspepsia. Aliment Pharmacol Ther. 2003;17:1215-27 pubmed
    Evidence for the effectiveness of antacids, histamine-2 receptor antagonists, bismuth salts, sucralfate and prokinetic therapy in non-ulcer dyspepsia is conflicting...
  26. Mannari C, Santi S, Migliori M, Filippi C, Origlia N, Sanso M, et al. Sucralfate modulates uPAR and EGFR expression in an experimental rat model of cervicitis. Int J Immunopathol Pharmacol. 2008;21:651-8 pubmed
    b>Sucralfate is a drug used in the treatment of gastric and duodenal ulcer; it is cytoprotective and able to increase the bioavailability of several growth factors, modulating the wound healing process...
  27. Delaney G, Fisher R, Hook C, Barton M. Sucralfate cream in the management of moist desquamation during radiotherapy. Australas Radiol. 1997;41:270-5 pubmed
    Randomized trials have shown that sucralfate is effective in the management of acute radiation reactions such as oesophagitis, mucositis and proctitis...
  28. Castagna L, Benhamou E, Pedraza E, Luboinski M, Forni M, Brandes I, et al. Prevention of mucositis in bone marrow transplantation: a double blind randomised controlled trial of sucralfate. Ann Oncol. 2001;12:953-5 pubmed
    ..In this double blind randomised study, we tested the efficacy of sucralfate for the prevention of mucositis induced by such conditioning treatments...
  29. Nottage M, McLachlan S, Brittain M, Oza A, Hedley D, Feld R, et al. Sucralfate mouthwash for prevention and treatment of 5-fluorouracil-induced mucositis: a randomized, placebo-controlled trial. Support Care Cancer. 2003;11:41-7 pubmed
    A randomized, double-blind, placebo-controlled trial was conducted to evaluate the effectiveness of a sucralfate mouthwash in preventing and alleviating oral mucositis induced by 5-fluorouracil (5FU)...
  30. Maruani A, Lorette G, Barbarot S, Potier A, Bessis D, Hasselmann C, et al. Re-emergence of papulonodular napkin dermatitis with use of reusable diapers: report of 5 cases. Eur J Dermatol. 2013;23:246-9 pubmed publisher
    ..We alert physicians to possible papulonodular napkin dermatitis in infants wearing reusable diapers. ..
  31. Chang P, Huang C, Rajan M, Hsin M. Revision with Totally Hand-Sewn Gastrojejunostomy and Vagotomy for Refractory Marginal Ulcer after Laparoscopic Roux-en-Y Gastric Bypass. Obes Surg. 2016;26:1150 pubmed publisher
    ..the gastroendoscopy revealed a marginal ulcer and she underwent medical treatment (proton pump inhibitor and sucralfate) for 3 months, but the patient's symptom aggravated and the serial gastroendoscopies still confirmed the ..
  32. Pettit M. Treatment of gastroesophageal reflux disease. Pharm World Sci. 2005;27:432-5 pubmed
    ..There are no clear data to support either treatment strategy as a universal approach to all patients; consequently, physicians must always choose the course best suited to the individual patient. ..
  33. Falkowski S, Trouillas P, Duroux J, Bonnetblanc J, Clavere P. Radiodermatitis prevention with sucralfate in breast cancer: fundamental and clinical studies. Support Care Cancer. 2011;19:57-65 pubmed publisher
    ..The present study concerns the protective effect of a 1% sucralfate lotion. We propose joint fundamental and clinical points of view...
  34. Lakshmi V, Singh N, Shrivastva S, Mishra S, Dharmani P, Mishra V, et al. Gedunin and photogedunin of Xylocarpus granatum show significant anti-secretory effects and protect the gastric mucosa of peptic ulcer in rats. Phytomedicine. 2010;17:569-74 pubmed publisher
    ..08% against AS and 69.42% against PL model and 70.79% against HA induced duodenal ulcer. Sucralfate, another standard drug (500 mg/kg, p.o.) showed 62.72% protection in AL induced ulcer model...
  35. Quenot J, Thiery N, Barbar S. When should stress ulcer prophylaxis be used in the ICU?. Curr Opin Crit Care. 2009;15:139-43 pubmed publisher
    ..b>Sucralfate, which can be administered by the nasogastric route, can protect the gastric mucosa without raising pH, but may ..
  36. Fujishiro M, Yahagi N, Oka M, Enomoto S, Yamamichi N, Kakushima N, et al. Endoscopic spraying of sucralfate using the outer sheath of a clipping device. Endoscopy. 2002;34:935 pubmed
  37. Sesler J. Stress-related mucosal disease in the intensive care unit: an update on prophylaxis. AACN Adv Crit Care. 2007;18:119-26; quiz 127-8 pubmed
    ..To minimize stress-related mucosal bleeding, several regimens have been used. This article presents an update on the incidence, pathophysiology, risk factors, and prophylaxis of SRMD. ..
  38. Haddock M, Sloan J, Bollinger J, Soori G, Steen P, Martenson J. Patient assessment of bowel function during and after pelvic radiotherapy: results of a prospective phase III North Central Cancer Treatment Group clinical trial. J Clin Oncol. 2007;25:1255-9 pubmed
    ..As part of a prospective randomized trial evaluating the impact of sucralfate on bowel function in patients receiving pelvic radiotherapy, patient-assessed bowel function data were collected ..
  39. Miyake K, Tsukui T, Shinji Y, Shinoki K, Hiratsuka T, Nishigaki H, et al. Teprenone, but not H2-receptor blocker or sucralfate, suppresses corpus Helicobacter pylori colonization and gastritis in humans: teprenone inhibition of H. pylori-induced interleukin-8 in MKN28 gastric epithelial cell lines. Helicobacter. 2004;9:130-7 pubmed
    ..we first compared the effect of teprenone with that of both histamine H2 receptor antagonists (H2-RA) and sucralfate on the histological scores of H. pylori gastritis. We then examined its in vitro effect on H...
  40. Lopriore E, Markhorst D, Gemke R. Ventilator-associated pneumonia and upper airway colonisation with Gram negative bacilli: the role of stress ulcer prophylaxis in children. Intensive Care Med. 2002;28:763-7 pubmed
    ..None. A total of 54 patients were given ranitidine, 53 patients were given sucralfate and 48 patients were given no stress ulcer prophylaxis. Thirteen (8.4%) patients developed VAP: 6 (11...
  41. de Rauglaudre G, Courdi A, Delaby Chagrin F, d Hombres A, Hannoun Levi J, Moureau Zabotto L, et al. [Tolerance of the association sucralfate / Cu-Zn salts in radiation dermatitis]. Ann Dermatol Venereol. 2008;Spec No 1:11-5 pubmed publisher
    The aim of this study was to evaluate the tolerance of topical application of the combination sucralfate / copper zinc salts in radiation dermatitis in women suffering from breast cancer and treated by radiotherapy...
  42. Sur R, Kochhar R, Singh D. Oral sucralfate in acute radiation oesophagitis. Acta Oncol. 1994;33:61-3 pubmed
    ..Group 1 (n = 40) received an antacid containing sodium alginate whereas Group 2 (n = 40) were given a 10% sucralfate suspension during 4 weeks...
  43. Widmark A, Fransson P, Franzen L, Littbrand B, Henriksson R. Daily-diary evaluated side-effects of conformal versus conventional prostatic cancer radiotherapy technique. Acta Oncol. 1997;36:499-507 pubmed
    ..Fifty-eight patients treated with the conventional technique (with or without sucralfate) were compared with 72 patients treated with conformal technique...
  44. Malairajan P, Gopalakrishnan G, Narasimhan S, Veni K, Kavimani S. Anti-ulcer activity of crude alcoholic extract of Toona ciliata Roemer (heart wood). J Ethnopharmacol. 2007;110:348-51 pubmed
    ..The plant extract also showed gastro protective activity (52.94%), whereas standard drug sucralfate showed 94.85%. Toona ciliata extract showed protection index 43...
  45. Hughes S. Canine gastrinoma: a case study and literature review of therapeutic options. N Z Vet J. 2006;54:242-7 pubmed
    ..A 6.2 kg, 8-year-old, spayed female Australian Terrier was presented with weight loss, inappetence, lethargy and a 2-day history of intermittent vomiting...
  46. Marini I, Vecchiet F. Sucralfate: a help during oral management in patients with epidermolysis bullosa. J Periodontol. 2001;72:691-5 pubmed
    ..The aim of this study was to evaluate the effectiveness of a sucralfate suspension in reducing both pain and the number of blisters in patients with EB, and to obtain improved oral ..
  47. Kukanich K, Kukanich B, Guess S, Heinrich E. Effect of Sucralfate on the Relative Bioavailability of Enrofloxacin and Ciprofloxacin in Healthy Fed Dogs. J Vet Intern Med. 2016;30:108-15 pubmed publisher
    b>Sucralfate impairs absorption of ciprofloxacin and other fluoroquinolones in humans, but no sucralfate-fluoroquinolone interaction has been reported in dogs...
  48. Nicaeus T, Tolentino M, Adamis A, Rubin P. Sucralfate and basic fibroblast growth factor promote endothelial cell proliferation around porous alloplastic implants in vitro. Ophthalmic Plast Reconstr Surg. 1996;12:235-9 pubmed
    ..Basic fibroblast growth factor (bFGF) is an angiogenic factor that promotes proliferation of endothelial cells. Sucralfate is known to bind bFGF and render it stable by protecting it from degradation...
  49. Ala S, Saeedi M, Janbabai G, Ganji R, Azhdari E, Shiva A. Efficacy of Sucralfate Mouth Wash in Prevention of 5-fluorouracil Induced Oral Mucositis: A Prospective, Randomized, Double-Blind, Controlled Trial. Nutr Cancer. 2016;68:456-63 pubmed publisher
    b>Sucralfate has been used for the prevention and treatment of radiotherapy- and chemotherapy-induced stomatitis and mucositis in a number of studies, but the results are contradictory...
  50. Si J, Wang C, Wu J. [Pharmacological effect and clinical application of protective agents of gastric mucosa]. Zhonghua Yi Xue Za Zhi. 2007;87:2955-7 pubmed
  51. Banati A, Chowdhury S, Mazumder S. Topical use of Sucralfate Cream in second and third degree burns. Burns. 2001;27:465-9 pubmed
    This clinical study was undertaken to test the efficacy of topical Sucralfate Cream in second and third degree burns...
  52. Vcev A, Vceva A, Kurbel S, Takac B, Stimac D, Ivandic A, et al. Amoxycillin, clarithromycin and either sucralfate or pantoprazole for eradication of Helicobacter pylori in duodenal ulcer (a randomized controlled trial). Wien Klin Wochenschr. 2001;113:939-41 pubmed
    b>Sucralfate enhances the anti-Helicobacter pylori activity of antimicrobials and has an inhibitory effect on H. pylori. To evaluate the efficacy and safety of one-week sucralfate-based eradication therapy for H...
  53. Hiramoto J, Terdiman J, Norton J. Evidence-based analysis: postoperative gastric bleeding: etiology and prevention. Surg Oncol. 2003;12:9-19 pubmed
    ..Histamine-2 receptor antagonists and sucralfate will reduce the likelihood of clinically important gastric-bleeding...