permethrin

Summary

Summary: A pyrethroid insecticide commonly used in the treatment of LICE INFESTATIONS and SCABIES.

Top Publications

  1. Mosha F, Lyimo I, Oxborough R, Matowo J, Malima R, Feston E, et al. Comparative efficacies of permethrin-, deltamethrin- and alpha-cypermethrin-treated nets, against Anopheles arabiensis and Culex quinquefasciatus in northern Tanzania. Ann Trop Med Parasitol. 2008;102:367-76 pubmed publisher
    Mosquito nets treated with permethrin, deltamethrin or alpha-cypermethrin at 25 mg/m(2) were evaluated in experimental huts in an area of rice irrigation near Moshi, in northern Tanzania...
  2. Pasay C, Mounsey K, Stevenson G, Davis R, Arlian L, Morgan M, et al. Acaricidal activity of eugenol based compounds against scabies mites. PLoS ONE. 2010;5:e12079 pubmed publisher
    ..Ordinary scabies is commonly treated with topical creams such as permethrin, while crusted scabies is treated with topical creams in combination with oral ivermectin...
  3. Amenya D, Naguran R, Lo T, Ranson H, Spillings B, Wood O, et al. Over expression of a cytochrome P450 (CYP6P9) in a major African malaria vector, Anopheles Funestus, resistant to pyrethroids. Insect Mol Biol. 2008;17:19-25 pubmed publisher
    ..This gene is genetically linked to a major locus associated with pyrethroid resistance in this A. funestus population. ..
  4. Chouaibou M, Etang J, Brevault T, Nwane P, Hinzoumbé C, Mimpfoundi R, et al. Dynamics of insecticide resistance in the malaria vector Anopheles gambiae s.l. from an area of extensive cotton cultivation in Northern Cameroon. Trop Med Int Health. 2008;13:476-86 pubmed publisher
    ..4% chlorpyrifos methyl (organophosphate), 0.1% propoxur (carbamate), 0.05% deltamethrin and 0.75% permethrin (pyrethroids). Throughout the survey, An. gambiae s.l...
  5. Marangi M, Cafiero M, Capelli G, Camarda A, Sparagano O, Giangaspero A. Evaluation of the poultry red mite, Dermanyssus gallinae (Acari: Dermanyssidae) susceptibility to some acaricides in field populations from Italy. Exp Appl Acarol. 2009;48:11-8 pubmed publisher
    ..for their susceptibility to acaricide formulations available on the market, containing amitraz, carbaryl and permethrin. A minimum of 3,000 mites of all stages were collected from each farm and were tested with five acaricide ..
  6. Griffioen K, van Gemst D, Pieterse M, Jacobs F, Sloet van Oldruitenborgh Oosterbaan M. Culicoides species associated with sheep in the Netherlands and the effect of a permethrin insecticide. Vet J. 2011;190:230-5 pubmed publisher
    ..2) the time of the day when they are most active; and (3) the effect of treatment of animals with a permethrin insecticide...
  7. Sharma S, Tyagi P, Upadhyay A, Haque M, Mohanty S, Raghavendra K, et al. Efficacy of permethrin treated long-lasting insecticidal nets on malaria transmission and observations on the perceived side effects, collateral benefits and human safety in a hyperendemic tribal area of Orissa, India. Acta Trop. 2009;112:181-7 pubmed publisher
    ..conducted on the efficacy of Olyset nets-a long-lasting insecticidal net (LLIN) factory treated with 2% (w/w) permethrin on malaria transmission in an area under the influence of pyrethroid susceptible vector species Anopheles ..
  8. Domínguez Renedo O, Alonso Lomillo M, Recio Cebrián P, Arcos Martínez M. Screen-printed acetylcholinesterase-based biosensors for inhibitive determination of permethrin. Sci Total Environ. 2012;426:346-50 pubmed publisher
    An amperometric assay based on acetylcholinesterase (AChE) inactivation has been developed for the monitoring of permethrin using a screen-printed three-electrode system...
  9. Fourie J, Beugnet F, Ollagnier C, Pollmeier M. Study of the sustained speed of kill of the combination of fipronil/amitraz/(S)-methoprene and the combination of imidacloprid/permethrin against Dermacentor reticulatus, the European dog tick. Parasite. 2011;18:319-23 pubmed
    ..of two topical combinations, one containing fipronil/amitraz/(S)-methoprene and the other, imidacloprid/permethrin, was evaluated in dogs...

More Information

Publications93

  1. Ramphul U, Boase T, Bass C, Okedi L, Donnelly M, Müller P. Insecticide resistance and its association with target-site mutations in natural populations of Anopheles gambiae from eastern Uganda. Trans R Soc Trop Med Hyg. 2009;103:1121-6 pubmed publisher
    ..sampled from two ecologically distinct breeding sites and exposed to WHO discriminating concentrations of DDT, permethrin, deltamethrin, bendiocarb and malathion. Survival rates to DDT were as high as 85...
  2. Faulde M, Uedelhoven W, Malerius M, Robbins R. Factory-based permethrin impregnation of uniforms: residual activity against Aedes aegypti and Ixodes ricinus in battle dress uniforms worn under field conditions, and cross-contamination during the laundering and storage process. Mil Med. 2006;171:472-7 pubmed
    The factory-based permethrin coating technique has only recently been developed...
  3. Tielemans E, Manavella C, Pollmeier M, Chester T, Murphy M, Gale B. Comparative acaricidal efficacy of the topically applied combinations fipronil/(S)-methoprene, permethrin/imidacloprid and metaflumizone/ amitraz against Dermacentor reticulatus, the European dog tick (ornate dog tick, Fabricius, 1794) in dogs. Parasite. 2010;17:343-8 pubmed
    ..dogs of the commercial topical combinations fipronil/(S)-methoprene (FRONTLINE Combo spot-on dog), imidacloprid/permethrin (Advantix) and metaflumizone/amitraz (ProMeris Duo) was evaluated and compared...
  4. Schleier J, Peterson R. Deposition and air concentrations of permethrin and naled used for adult mosquito management. Arch Environ Contam Toxicol. 2010;58:105-11 pubmed publisher
    ..the management of adult mosquitoes, we conducted an environmental fate study after truck-mounted applications of permethrin and naled...
  5. Chang C, Shen W, Wang T, Lin Y, Hsu E, Dai S. A novel amino acid substitution in a voltage-gated sodium channel is associated with knockdown resistance to permethrin in Aedes aegypti. Insect Biochem Mol Biol. 2009;39:272-8 pubmed publisher
    To identify pertinent mutations associated with knockdown resistance to permethrin, the entire coding sequence of the voltage-gated sodium channel gene Aa-para was sequenced and analyzed from a Per-R strain with 190-fold resistance to ..
  6. Heukelbach J, Pilger D, Oliveira F, Khakban A, Ariza L, Feldmeier H. A highly efficacious pediculicide based on dimeticone: randomized observer blinded comparative trial. BMC Infect Dis. 2008;8:115 pubmed publisher
    ..In this trial we assessed the efficacy of a product containing a high (92%) concentration of the silicone oil dimeticone (identical in composition to NYDA(R)), as compared to a 1% permethrin lotion.
  7. Himeidan Y, Muzamil H, Jones C, Ranson H. Extensive permethrin and DDT resistance in Anopheles arabiensis from eastern and central Sudan. Parasit Vectors. 2011;4:154 pubmed publisher
    ..This study assessed resistance to permethrin and DDT in seven populations of Anopheles arabiensis from Sudan...
  8. Reid W, Zhang L, Liu F, Liu N. The transcriptome profile of the mosquito Culex quinquefasciatus following permethrin selection. PLoS ONE. 2012;7:e47163 pubmed publisher
    ..in mosquitoes Culex quinquefasciatus, we conducted a whole transcriptome analysis of Culex mosquitoes following permethrin selection...
  9. Riaz M, Poupardin R, Reynaud S, Strode C, Ranson H, David J. Impact of glyphosate and benzo[a]pyrene on the tolerance of mosquito larvae to chemical insecticides. Role of detoxification genes in response to xenobiotics. Aquat Toxicol. 2009;93:61-9 pubmed publisher
    ..aromatic hydrocarbon benzo[a]pyrene on their subsequent tolerance to the chemical insecticides imidacloprid, permethrin and propoxur, detoxification enzyme activities and transcription of detoxification genes was investigated...
  10. M ller P, Warr E, Stevenson B, Pignatelli P, Morgan J, Steven A, et al. Field-caught permethrin-resistant Anopheles gambiae overexpress CYP6P3, a P450 that metabolises pyrethroids. PLoS Genet. 2008;4:e1000286 pubmed publisher
    ..This is the first study to demonstrate the capacity of a P450 identified in wild A. gambiae to metabolise insecticides. The findings add to the understanding of the genetic basis of insecticide resistance in wild mosquito populations...
  11. Rossbach B, Appel K, Mross K, Letzel S. Uptake of permethrin from impregnated clothing. Toxicol Lett. 2010;192:50-5 pubmed publisher
    In order to examine exposure and health risks which can arise from permethrin-impregnated clothing, a controlled trial was conducted...
  12. Wilding C, Smith I, Lynd A, Yawson A, Weetman D, Paine M, et al. A cis-regulatory sequence driving metabolic insecticide resistance in mosquitoes: functional characterisation and signatures of selection. Insect Biochem Mol Biol. 2012;42:699-707 pubmed publisher
    ..element is found directly upstream of CYP9M10, a cytochrome P450 implicated previously in larval resistance to permethrin in the ISOP450 strain of Culex quinquefasciatus, but is absent from the equivalent genomic region of a ..
  13. Molina R, Espinosa Gongora C, Galvez R, Montoya A, Descalzo M, Jiménez M, et al. Efficacy of 65% permethrin applied to dogs as a spot-on against Phlebotomus perniciosus. Vet Parasitol. 2012;187:529-33 pubmed publisher
    ..infantum. The present study was designed to test the efficacy of 65% permethrin applied to dogs as a spot-on against the sand fly vector Phlebotomus perniciosus...
  14. Pasay C, Arlian L, Morgan M, Vyszenski Moher D, Rose A, Holt D, et al. High-resolution melt analysis for the detection of a mutation associated with permethrin resistance in a population of scabies mites. Med Vet Entomol. 2008;22:82-8 pubmed publisher
    b>Permethrin as a topical acaricide cream is widely used to treat scabies...
  15. Abdullah L, Evans J, Montague H, Reed J, Moser A, Crynen G, et al. Chronic elevation of phosphocholine containing lipids in mice exposed to Gulf War agents pyridostigmine bromide and permethrin. Neurotoxicol Teratol. 2013;40:74-84 pubmed publisher
    ..Gulf War agents such as the acetylcholinesterase (AChE) inhibitor pyridostigmine bromide (PB) and the pesticide permethrin (PER) are considered key etiogenic factors in GWI...
  16. Carloni M, Nasuti C, Fedeli D, Montani M, Vadhana M, Amici A, et al. Early life permethrin exposure induces long-term brain changes in Nurr1, NF-kB and Nrf-2. Brain Res. 2013;1515:19-28 pubmed publisher
    ..Here, the impact of permethrin administered to rats from 6th to 21st day of life, at a dose near to "no observed adverse effect level"..
  17. Himeidan Y, Chen H, Chandre F, Donnelly M, Yan G. Short report: permethrin and DDT resistance in the malaria vector Anopheles arabiensis from eastern Sudan. Am J Trop Med Hyg. 2007;77:1066-8 pubmed
    Assessment of resistance to DDT and permethrin insecticides and molecular detection of knockdown resistance (kdr) alleles were conducted in three populations of Anopheles arabiensis from eastern Sudan. Bioassay mortalities ranged from 96...
  18. Klinkenberg E, McCall P, Wilson M, Amerasinghe F, Donnelly M. Impact of urban agriculture on malaria vectors in Accra, Ghana. Malar J. 2008;7:151 pubmed publisher
    ..Host-seeking activity peaked between 2-3 am, indicating that insecticide-treated bednets should be an effective control method. ..
  19. Jin Y, Chen R, Sun L, Wang W, Zhou L, Liu W, et al. Enantioselective induction of estrogen-responsive gene expression by permethrin enantiomers in embryo-larval zebrafish. Chemosphere. 2009;74:1238-44 pubmed publisher
    ..the induction of estrogen-responsive gene expression in embryo-larval zebrafish after 7 d of exposure to permethrin (PM) enantiomers. The PM enantiomers were completely separated by a chiral HPLC column...
  20. Harrill J, Li Z, Wright F, Radio N, Mundy W, Tornero Velez R, et al. Transcriptional response of rat frontal cortex following acute in vivo exposure to the pyrethroid insecticides permethrin and deltamethrin. BMC Genomics. 2008;9:546 pubmed publisher
    ..Rats were acutely exposed to either deltamethrin (0.3 - 3 mg/kg) or permethrin (1 - 100 mg/kg) followed by collection of cortical tissue at 6 hours...
  21. Matowo J, Kulkarni M, Mosha F, Oxborough R, Kitau J, Tenu F, et al. Biochemical basis of permethrin resistance in Anopheles arabiensis from Lower Moshi, north-eastern Tanzania. Malar J. 2010;9:193 pubmed publisher
    ..In this study, metabolic-based mechanisms conferring permethrin (pyrethroid) resistance were investigated in Anopheles arabiensis of Lower Moshi, Kilimanjaro region of north-..
  22. SupYoon K, Symington S, Hyeock Lee S, Soderlund D, Marshall Clark J. Three mutations identified in the voltage-sensitive sodium channel alpha-subunit gene of permethrin-resistant human head lice reduce the permethrin sensitivity of house fly Vssc1 sodium channels expressed in Xenopus oocytes. Insect Biochem Mol Biol. 2008;38:296-306 pubmed publisher
    ..para-orthologous sodium channel alpha-subunit of the head louse (M815I, T917I, and L920F) are associated with permethrin resistance and DDT resistance...
  23. Protopopoff N, Verhaeghen K, Van Bortel W, Roelants P, Marcotty T, Baza D, et al. A significant increase in kdr in Anopheles gambiae is associated with an intensive vector control intervention in Burundi highlands. Trop Med Int Health. 2008;13:1479-87 pubmed publisher
    ..In bioassays conducted between 2005 and 2007 at five sites, An. funestus was susceptible to permethrin, deltamethrin and DDT. Anopheles gambiae s.l...
  24. Currie B, McCarthy J. Permethrin and ivermectin for scabies. N Engl J Med. 2010;362:717-25 pubmed publisher
  25. Nasuti C, Carloni M, Fedeli D, Gabbianelli R, Di Stefano A, Serafina C, et al. Effects of early life permethrin exposure on spatial working memory and on monoamine levels in different brain areas of pre-senescent rats. Toxicology. 2013;303:162-8 pubmed publisher
    ..Previous studies investigated the effect of permethrin (PERM) administered at 34 mg/kg, a dose close to the no observable adverse effect level (NOAEL) from post natal ..
  26. Mounsey K, Holt D, McCarthy J, Currie B, Walton S. Scabies: molecular perspectives and therapeutic implications in the face of emerging drug resistance. Future Microbiol. 2008;3:57-66 pubmed publisher
    ..effective treatments, coupled with recent observations of emerging drug resistance to oral ivermectin and 5% permethrin, raise concerns regarding the future control of scabies, especially in severe cases and in endemic areas where ..
  27. Farenhorst M, Knols B, Thomas M, Howard A, Takken W, Rowland M, et al. Synergy in efficacy of fungal entomopathogens and permethrin against West African insecticide-resistant Anopheles gambiae mosquitoes. PLoS ONE. 2010;5:e12081 pubmed publisher
    ..This study investigated the compatibility of the pyrethroid insecticide permethrin and two mosquito-pathogenic fungi, Beauveria bassiana and Metarhizium anisopliae, against a laboratory colony ..
  28. Liu N, Li T, Reid W, Yang T, Zhang L. Multiple Cytochrome P450 genes: their constitutive overexpression and permethrin induction in insecticide resistant mosquitoes, Culex quinquefasciatus. PLoS ONE. 2011;6:e23403 pubmed publisher
    ..The P450 gene expression and induction by permethrin were compared for three different mosquito populations bearing different resistance phenotypes, ranging from ..
  29. Wang D, Kamijima M, Okamura A, Ito Y, Yanagiba Y, Jia X, et al. Evidence for diazinon-mediated inhibition of cis-permethrin metabolism and its effects on reproductive toxicity in adult male mice. Reprod Toxicol. 2012;34:489-97 pubmed publisher
    ..We evaluated male reproductive toxicity in mice co-exposed to diazinon and cis-permethrin. Nine-week-old male Sv/129 mice were exposed to diazinon (10 ?mol/kg/day) or cis-permethrin (90 ?mol/kg/day) ..
  30. Rusiecki J, Patel R, Koutros S, Beane Freeman L, Landgren O, Bonner M, et al. Cancer incidence among pesticide applicators exposed to permethrin in the Agricultural Health Study. Environ Health Perspect. 2009;117:581-6 pubmed publisher
    b>Permethrin is a synthetic pyrethroid insecticide widely used in agriculture, in public health, and in many U.S. homes and gardens...
  31. Roma G, Furquim K, Bechara G, Camargo Mathias M. Permethrin-induced morphological changes in oocytes of Rhipicephalus sanguineus (Acari: Ixodidae) semi-engorged females. Food Chem Toxicol. 2010;48:825-30 pubmed publisher
    The permethrin, active ingredient of the Advantage(R) Max3--Bayer, has been widely used in the chemical control of ticks. These ectoparasites are one of the most important animal groups that cause serious damage to their hosts...
  32. Vaughn M, Meshnick S. Pilot study assessing the effectiveness of long-lasting permethrin-impregnated clothing for the prevention of tick bites. Vector Borne Zoonotic Dis. 2011;11:869-75 pubmed publisher
    ..Treatment of clothing with permethrin, a nontoxic chemical with insecticidal, knockdown, and repellent properties, is highly effective against ticks...
  33. Pitzer J, Kaufman P, Tenbroeck S. Assessing permethrin resistance in the stable fly (Diptera: Muscidae) in Florida by using laboratory selections and field evaluations. J Econ Entomol. 2010;103:2258-63 pubmed
    ..Stable fly susceptibility to a commonly used pyrethroid, permethrin, was determined in Florida to assess the possibility of resistance development...
  34. Dryden M, Payne P, VICKI S, Riggs B, Davenport J, Kobuszewski D. Efficacy of dinotefuran-pyriproxyfen, dinotefuran-pyriproxyfen-permethrin and fipronil-(S)-methoprene topical spot-on formulations to control flea populations in naturally infested pets and private residences in Tampa, FL. Vet Parasitol. 2011;182:281-6 pubmed publisher
    ..00%, w/w) (DP) or dinotefuran (4.95%, w/w)/pyriproxyfen (0.44%, w/w)/permethrin (36.08%, w/w) (DPP) topical spot-on, respectively...
  35. Yang T, Liu N. Genome analysis of cytochrome P450s and their expression profiles in insecticide resistant mosquitoes, Culex quinquefasciatus. PLoS ONE. 2011;6:e29418 pubmed publisher
    ..populations of mosquitoes (HAmCq and MAmCq), and field parental mosquitoes (HAmCq(G0) and MAmCq(G0)) and their permethrin selected offspring (HAmCq(G8) and MAmCq(G6))...
  36. Li A, Davey R, Miller R, Guerrero F, George J. Genetics and mechanisms of permethrin resistance in the Santa Luiza strain of Boophilus microplus (Acari: Ixodidae). J Med Entomol. 2008;45:427-38 pubmed
    ..strain of the southern cattle tick, Boophilus microplus (Canestrini) (Acari: Ixodidae), is resistant to both permethrin and amitraz...
  37. Yang D, Pearce R, Wang X, Gaedigk R, Wan Y, Yan B. Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin. Biochem Pharmacol. 2009;77:238-47 pubmed publisher
  38. Chan H, Zairi J. Permethrin resistance in Aedes albopictus (Diptera: Culicidae) and associated fitness costs. J Med Entomol. 2013;50:362-70 pubmed
    ..The selection of a colony of permethrin-resistant Aedes albopictus (Skuse) (Diptera: Culicidae), originating from Penang Island, Malaysia, yielded high ..
  39. Mzilahowa T, Ball A, Bass C, Morgan J, Nyoni B, Steen K, et al. Reduced susceptibility to DDT in field populations of Anopheles quadriannulatus and Anopheles arabiensis in Malawi: evidence for larval selection. Med Vet Entomol. 2008;22:258-63 pubmed publisher
    ..The results indicate full susceptibility to permethrin, deltamethrin and malathion, but reduced susceptibility to DDT in one sample from Thom (LT(50) of 8...
  40. Bouvresse S, Berdjane Z, Durand R, Bouscaillou J, Izri A, Chosidow O. Permethrin and malathion resistance in head lice: results of ex vivo and molecular assays. J Am Acad Dermatol. 2012;67:1143-50 pubmed publisher
    ..Overuse of these products has led to the emergence of resistance to pyrethroids and malathion worldwide. Permethrin resistance in head lice is mostly conferred by the knockdown resistance (kdr) trait...
  41. Miller N, Rainone E, Dyer M, González M, Mather T. Tick bite protection with permethrin-treated summer-weight clothing. J Med Entomol. 2011;48:327-33 pubmed
    The number of tick bites received by individuals wearing either permethrin-treated or untreated summer clothing (T-shirt, shorts, socks, and sneakers) was compared during a controlled indoor study...
  42. Okoye P, Brooke B, Koekemoer L, Hunt R, Coetzee M. Inheritance of pyrethroid resistance in the major malaria vector in southern Africa, Anopheles funestus. Ann Trop Med Parasitol. 2008;102:275-81 pubmed publisher
  43. Zhang S, Ueyama J, Ito Y, Yanagiba Y, Okamura A, Kamijima M, et al. Permethrin may induce adult male mouse reproductive toxicity due to cis isomer not trans isomer. Toxicology. 2008;248:136-41 pubmed publisher
    b>Permethrin, the most popular insecticide among the synthetic pyrethroids, has been used worldwide to control a wide range of insects in agriculture, forestry, public health, and homes...
  44. Soleimani Ahmadi M, Vatandoost H, Shaeghi M, Raeisi A, Abedi F, Eshraghian M, et al. Field evaluation of permethrin long-lasting insecticide treated nets (Olyset(®)) for malaria control in an endemic area, southeast of Iran. Acta Trop. 2012;123:146-53 pubmed publisher
    ..3%±7.07 in baseline and after 1 year of intervention, respectively. The average permethrin content reached to 68.31% (683.1mg/m(2)) of the initial insecticide dose of 937±21...
  45. Srisawat R, Komalamisra N, Apiwathnasorn C, Paeporn P, Roytrakul S, Rongsriyam Y, et al. Field-collected permethrin-resistant Aedes aegypti from central Thailand contain point mutations in the domain IIS6 of the sodium channel gene (KDR). Southeast Asian J Trop Med Public Health. 2012;43:1380-6 pubmed
    ..Partial fragment of kdr of permethrin-resistant mosquitoes were amplified by RT-PCR and sequenced...
  46. Abate A, Hadis M. Susceptibility of Anopheles gambiae s.l. to DDT, malathion, permethrin and deltamethrin in Ethiopia. Trop Med Int Health. 2011;16:486-91 pubmed publisher
    To assess the susceptibility/resistance level of Anopheles gambiae s.l. to DDT, malathion, permethrin and deltamethrin in different parts of Ethiopia. Field collected female An.gambiae s.l...
  47. Bouhsira E, Lienard E, Jacquiet P, Warin S, Kaltsatos V, Baduel L, et al. Efficacy of permethrin, dinotefuran and pyriproxyfen on adult fleas, flea eggs collection, and flea egg development following transplantation of mature female fleas (Ctenocephalides felis felis) from cats to dogs. Vet Parasitol. 2012;190:541-6 pubmed publisher
    A novel spot-on formulation combining permethrin, pyriproxifen and dinotefuran (Vectra 3D™ spot-on solution for dogs) was evaluated in adult Beagle dogs in a study to determine adulticidal efficacy, egg laying inhibition and viability ..
  48. Stough D, Shellabarger S, Quiring J, Gabrielsen A. Efficacy and safety of spinosad and permethrin creme rinses for pediculosis capitis (head lice). Pediatrics. 2009;124:e389-95 pubmed publisher
    Studies compared spinosad creme rinse and permethrin lice treatment under "actual-use" conditions for pediculosis capitis (head lice). Two phase-3, multicenter, randomized, evaluator/investigator-blinded studies compared 0...
  49. Verhaeghen K, Bortel W, Roelants P, Okello P, Talisuna A, Coosemans M. Spatio-temporal patterns in kdr frequency in permethrin and DDT resistant Anopheles gambiae s.s. from Uganda. Am J Trop Med Hyg. 2010;82:566-73 pubmed publisher
    ..This study showed that kdr might have an epidemiological impact that could jeopardize the vector control strategies. ..
  50. Djouaka R, Bakare A, Coulibaly O, Akogbeto M, Ranson H, Hemingway J, et al. Expression of the cytochrome P450s, CYP6P3 and CYP6M2 are significantly elevated in multiple pyrethroid resistant populations of Anopheles gambiae s.s. from Southern Benin and Nigeria. BMC Genomics. 2008;9:538 pubmed publisher
    ..All mosquitoes sampled belonged to the M form of An. gambiae s.s. There were high levels of permethrin resistance in an agricultural area (Akron) and an urban area (Gbedjromede), low levels of resistance in mosquito ..
  51. Oliveira F, Speare R, Heukelbach J. High in vitro efficacy of Nyda L, a pediculicide containing dimeticone. J Eur Acad Dermatol Venereol. 2007;21:1325-9 pubmed
    ..The therapy of pediculosis remains a common problem in clinical practice. As resistance to commonly used chemical pediculicides is constantly increasing, there is a need for new effective compounds...
  52. Zhu F, Feng J, Zhang L, Liu N. Characterization of two novel cytochrome P450 genes in insecticide-resistant house-flies. Insect Mol Biol. 2008;17:27-37 pubmed publisher
    ..This evidence suggests the importance of CYP6A36 in detoxification of insecticides and evolution of insecticide resistance in ALHF...
  53. Yan Y, Yang Y, You J, Yang G, Xu Y, Huang N, et al. Permethrin modulates cholinergic mini-synaptic currents by partially blocking the calcium channel. Toxicol Lett. 2011;201:258-63 pubmed publisher
    ..The effects of permethrin, a putative calcium antagonist, on calcium current and cholinergic mini-synaptic transmission were investigated ..
  54. Zhu F, Li T, Zhang L, Liu N. Co-up-regulation of three P450 genes in response to permethrin exposure in permethrin resistant house flies, Musca domestica. BMC Physiol. 2008;8:18 pubmed publisher
    ..The current study focuses on the characterization of individual P450 genes that are induced in response to permethrin treatment in permethrin resistant house flies. ..
  55. Saavedra Rodriguez K, Strode C, Flores Suarez A, Fernandez Salas I, Ranson H, Hemingway J, et al. Quantitative trait loci mapping of genome regions controlling permethrin resistance in the mosquito Aedes aegypti. Genetics. 2008;180:1137-52 pubmed publisher
    The mosquito Aedes aegypti is the principal vector of dengue and yellow fever flaviviruses. Permethrin is an insecticide used to suppress Ae...
  56. Van Bortel W, Trung H, Thuan L, Sochantha T, Socheat D, Sumrandee C, et al. The insecticide resistance status of malaria vectors in the Mekong region. Malar J. 2008;7:102 pubmed publisher
    ..were performed on adult mosquitoes using the standard WHO susceptibility test with diagnostic concentrations of permethrin 0.75% and DDT 4%...
  57. Shafer T, Rijal S, Gross G. Complete inhibition of spontaneous activity in neuronal networks in vitro by deltamethrin and permethrin. Neurotoxicology. 2008;29:203-12 pubmed publisher
    ..To characterize better pyrethroid actions at the network level, effects of the Type I pyrethroid permethrin (PM) and the Type II pyrethroid deltamethrin (DM) on spontaneous glutamate network-dependent spikes and bursts ..
  58. Ding Y, Landrum P, You J, Lydy M. Assessing bioavailability and toxicity of permethrin and DDT in sediment using matrix solid phase microextraction. Ecotoxicology. 2013;22:109-17 pubmed publisher
    ..was evaluated as a surrogate for the absorbed dose in organisms to estimate bioavailability and toxicity of permethrin and dichlorodiphenyltrichloroethane (DDT) in laboratory-spiked sediment...
  59. Hardstone M, Leichter C, Scott J. Multiplicative interaction between the two major mechanisms of permethrin resistance, kdr and cytochrome P450-monooxygenase detoxification, in mosquitoes. J Evol Biol. 2009;22:416-23 pubmed publisher
    ..The two major mechanisms that confer resistance to permethrin in Culex mosquitoes are target site insensitivity (i.e...
  60. Toloza A, Lucia A, Zerba E, Masuh H, Picollo M. Interspecific hybridization of Eucalyptus as a potential tool to improve the bioactivity of essential oils against permethrin-resistant head lice from Argentina. Bioresour Technol. 2008;99:7341-7 pubmed publisher
    ..grandisxE. tereticornis were analyzed by GC-MS, and evaluated for their fumigant and repellent effects on permethrin-resistant head lice. Fumigant activity of both hybrids was higher than that for pure species. E. grandisxE...
  61. Takaku T, Mikata K, Matsui M, Nishioka K, Isobe N, Kaneko H. In vitro metabolism of trans-permethrin and its major metabolites, PBalc and PBacid, in humans. J Agric Food Chem. 2011;59:5001-5 pubmed publisher
    To estimate the metabolic profile of trans-permethrin in humans, a comparison of the in vitro metabolism of trans-permethrin in humans and rats was conducted using hepatic microsomes, and cytochrome P450 and UDP-glucuronyltransferase ..
  62. Somwang P, Yanola J, Suwan W, Walton C, Lumjuan N, Prapanthadara L, et al. Enzymes-based resistant mechanism in pyrethroid resistant and susceptible Aedes aegypti strains from northern Thailand. Parasitol Res. 2011;109:531-7 pubmed publisher
    Previous studies have shown that permethrin resistance in our selected PMD-R strain of Aedes aegypti from Chiang Mai, Thailand, was associated with a homozygous mutation in the knockdown resistance (kdr) gene and other mechanisms...
  63. Hardstone M, Komagata O, Kasai S, Tomita T, Scott J. Use of isogenic strains indicates CYP9M10 is linked to permethrin resistance in Culex pipiens quinquefasciatus. Insect Mol Biol. 2010;19:717-26 pubmed publisher
    Previous studies on a strain of Culex pipiens quinquefasciatus from Saudi Arabia indicated permethrin resistance was a result of cytochrome P450 mediated detoxification and kdr...
  64. Li T, Zhang L, Reid W, Xu Q, Dong K, Liu N. Multiple mutations and mutation combinations in the sodium channel of permethrin resistant mosquitoes, Culex quinquefasciatus. Sci Rep. 2012;2:781 pubmed publisher
    ..The current study therefore further characterized these mutations and their combinations in other field and permethrin selected Culex mosquitoes, finding that the co-existence of all 9 mutations was indeed correlated with the high ..
  65. Manikkam M, Tracey R, Guerrero Bosagna C, Skinner M. Pesticide and insect repellent mixture (permethrin and DEET) induces epigenetic transgenerational inheritance of disease and sperm epimutations. Reprod Toxicol. 2012;34:708-19 pubmed publisher
    ..The current study was designed to determine if a "pesticide mixture" (pesticide permethrin and insect repellent N,N-diethyl-meta-toluamide, DEET) promotes epigenetic transgenerational inheritance of ..
  66. Ferroglio E, Poggi M, Trisciuoglio A. Evaluation of 65% permethrin spot-on and deltamethrin-impregnated collars for canine Leishmania infantum infection prevention. Zoonoses Public Health. 2008;55:145-8 pubmed publisher
    During the 2004 and 2005 sand fly seasons, we evaluated the efficacy of a 65% spot-on solution of permethrin (Exspot, Schering & Plough) and deltamethrin-impregnated collar (Scalibor, Intervet) in reducing Leishmania infantum ..
  67. Hu F, Li L, Wang C, Zhang Q, Zhang X, Zhao M. Enantioselective induction of oxidative stress by permethrin in rat adrenal pheochromocytoma (PC12) cells. Environ Toxicol Chem. 2010;29:683-90 pubmed publisher
    ..Therefore, this study was undertaken to evaluate the role of oxidative stress in enantiomer-specific permethrin (PM)-induced cytotoxicity in rat adrenal pheochromocytoma (PC12) cells...
  68. Dabire K, Diabate A, Agostinho F, Alves F, Manga L, Faye O, et al. Distribution of the members of Anopheles gambiae and pyrethroid knock-down resistance gene (kdr) in Guinea-Bissau, West Africa. Bull Soc Pathol Exot. 2008;101:119-23 pubmed
    ..mangrove to savannah ii) to evaluate the insecticide susceptibility status of these malaria vectors exposed to permethrin 0...
  69. Tulve N, Egeghy P, Fortmann R, Whitaker D, Nishioka M, Naeher L, et al. Multimedia measurements and activity patterns in an observational pilot study of nine young children. J Expo Sci Environ Epidemiol. 2008;18:31-44 pubmed
    ..Cis-permethrin, trans-permethrin, and cypermethrin were measured in all nine homes...
  70. Drali R, Benkouiten S, Badiaga S, Bitam I, Rolain J, Brouqui P. Detection of a knockdown resistance mutation associated with permethrin resistance in the body louse Pediculus humanus corporis by use of melting curve analysis genotyping. J Clin Microbiol. 2012;50:2229-33 pubmed publisher
    ..We aim to develop a rapid and robust genotyping method usable in large field-based clinical studies to monitor permethrin resistance in the human body louse Pediculus humanus corporis...
  71. Bautista M, Miyata T, Miura K, Tanaka T. RNA interference-mediated knockdown of a cytochrome P450, CYP6BG1, from the diamondback moth, Plutella xylostella, reduces larval resistance to permethrin. Insect Biochem Mol Biol. 2009;39:38-46 pubmed publisher
    ..that a cytochrome P450, CYP6BG1, from Plutella xylostella was found to be overexpressed in 4th instars of a permethrin resistant strain and inducible in the susceptible counterpart...
  72. Pasay C, Arlian L, Morgan M, Gunning R, Rossiter L, Holt D, et al. The effect of insecticide synergists on the response of scabies mites to pyrethroid acaricides. PLoS Negl Trop Dis. 2009;3:e354 pubmed publisher
    b>Permethrin is the active component of topical creams widely used to treat human scabies. Recent evidence has demonstrated that scabies mites are becoming increasingly tolerant to topical permethrin and oral ivermectin...
  73. Burgess I, Brunton E, Burgess N. Clinical trial showing superiority of a coconut and anise spray over permethrin 0.43% lotion for head louse infestation, ISRCTN96469780. Eur J Pediatr. 2010;169:55-62 pubmed publisher
    b>Permethrin is the most widely used pediculicide, but evidence of resistance from several countries and anecdotal reports from Germany suggest that permethrin lotion is now less effective...
  74. Ranson H, Abdallah H, Badolo A, Guelbeogo W, Kerah Hinzoumbé C, Yangalbé Kalnoné E, et al. Insecticide resistance in Anopheles gambiae: data from the first year of a multi-country study highlight the extent of the problem. Malar J. 2009;8:299 pubmed publisher
    ..The current extent and distribution of this resistance in many parts of the continent is unknown and yet such information is essential for the planning of effective malaria control interventions...
  75. Deus K, Saavedra Rodriguez K, Butters M, Black W, Foy B. The effect of ivermectin in seven strains of Aedes aegypti (Diptera: Culicidae) including a genetically diverse laboratory strain and three permethrin resistant strains. J Med Entomol. 2012;49:356-63 pubmed
    ..including a genetically diverse laboratory strain, three laboratory-selected permethrin-resistant strains, a standard reference strain, and two recently colonized strains were fed on human blood ..
  76. Das M, Roy L, Picado A, Kroeger A, Rijal S, Boelaert M. Deltamethrin and permethrin residue on long-lasting insecticidal nets after 18 months of use in a visceral leishmaniasis-endemic area in Nepal. Trans R Soc Trop Med Hyg. 2012;106:230-4 pubmed publisher
    ..5 mg/m(2) (97.3% of the target dose) of deltamethrin and 911.8 mg/m(2) (91.2% of the target dose) of permethrin, respectively...
  77. Williams M, Rundle A, Holmes D, Reyes M, Hoepner L, Barr D, et al. Changes in pest infestation levels, self-reported pesticide use, and permethrin exposure during pregnancy after the 2000-2001 U.S. Environmental Protection Agency restriction of organophosphates. Environ Health Perspect. 2008;116:1681-8 pubmed publisher
    ..511 pregnant women from inner-city New York were enrolled between 2000 and 2006. Permethrin, a pyrethroid insecticide; piperonyl butoxide (PBO), a pyrethroid synergist; chlorpyrifos; and diazinon were ..
  78. Brander S, He G, Smalling K, Denison M, Cherr G. The in vivo estrogenic and in vitro anti-estrogenic activity of permethrin and bifenthrin. Environ Toxicol Chem. 2012;31:2848-55 pubmed publisher
    ..Their intended mechanism is prolonged sodium channel opening, but recent studies reveal that pyrethroids such as permethrin and bifenthrin also have endocrine activity...
  79. Hardstone M, Lazzaro B, Scott J. The effect of three environmental conditions on the fitness of cytochrome P450 monooxygenase-mediated permethrin resistance in Culex pipiens quinquefasciatus. BMC Evol Biol. 2009;9:42 pubmed publisher
    ..One strain (ISOP450) was permethrin resistant (due to P450-mediated detoxification) and one was a susceptible strain...
  80. Pridgeon J, Becnel J, Clark G, Linthicum K. Permethrin induces overexpression of multiple genes in Aedes aegypti. J Med Entomol. 2009;46:580-7 pubmed
    ..chain reaction (PCR)-select subtractive cDNA hybridization technique, 18 different genes were isolated from a permethrin-treated versus acetone-treated Aedes aegypti subtractive library...
  81. Pennetier C, Bouraima A, Chandre F, Piameu M, Etang J, Rossignol M, et al. Efficacy of Olyset® Plus, a new long-lasting insecticidal net incorporating permethrin and piperonyl-butoxide against multi-resistant malaria vectors [corrected]. PLoS ONE. 2013;8:e75134 pubmed publisher
    ..Olyset® Plus is a new long-lasting insecticidal net (LLIN) incorporating permethrin and a synergist, piperonyl butoxide (PBO), into its fibres in order to counteract metabolic-based pyrethroid ..
  82. Yewhalaw D, Bortel W, Denis L, Coosemans M, Duchateau L, Speybroeck N. First evidence of high knockdown resistance frequency in Anopheles arabiensis (Diptera: Culicidae) from Ethiopia. Am J Trop Med Hyg. 2010;83:122-5 pubmed publisher
    ..Moreover, the mortality of An. gambiae s.l. to diagnostic dosages of 4% DDT, 0.75% permethrin, and 0.05% deltamethrin from bioassay results was 1.0%, 18.1%, and 82.2%, respectively...
  83. Turkez H, Toğar B. Olive (Olea europaea L.) leaf extract counteracts genotoxicity and oxidative stress of permethrin in human lymphocytes. J Toxicol Sci. 2011;36:531-7 pubmed
    ..of olive leaf extract (OLE) on genotoxicity and oxidative damage in cultured human blood cells treated with permethrin (PM) in the presence of a rat liver S9 mix containing cytochrome P 450 enzymes...
  84. Abedin S, Narang M, Gandhi V, Narang S. Efficacy of permethrin cream and oral ivermectin in treatment of scabies. Indian J Pediatr. 2007;74:915-6 pubmed
    To compare the efficacy of mass treatment of scabies with permethrin cream and oral ivermectin in a closed urban pediatric population...