hexachlorobenzene

Summary

Summary: An agricultural fungicide and seed treatment agent.

Top Publications

  1. Mahalingaiah S, Missmer S, MAITY A, Williams P, Meeker J, Berry K, et al. Association of hexachlorobenzene (HCB), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichloroethylene (DDE) with in vitro fertilization (IVF) outcomes. Environ Health Perspect. 2012;120:316-20 pubmed publisher
    b>Hexachlorobenzene (HCB), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichloroethylene (DDE) are persistent chlorinated pesticides with endocrine activity that may adversely affect the early stages of human reproduction...
  2. Hagmar L, Wallin E, Vessby B, Jönsson B, Bergman A, Rylander L. Intra-individual variations and time trends 1991-2001 in human serum levels of PCB, DDE and hexachlorobenzene. Chemosphere. 2006;64:1507-13 pubmed
    ..of 2,2',4,4',5,5'-hexachlorobiphenyl (CB-153), 1,1-dichloro-2,2-bis(4-chlorophenyl)-ethene (p,p'-DDE) and hexachlorobenzene (HCB), considering the impact of a number of possible determinants...
  3. Porta M, Jariod M, López T, Pumarega J, Puigdomenech E, Marco E, et al. Correcting serum concentrations of organochlorine compounds by lipids: alternatives to the organochlorine/total lipids ratio. Environ Int. 2009;35:1080-5 pubmed publisher
    ..They suggest that it is unwarranted to routinely correct OC by TL, offer ways to assess such need, and present alternatives as no TL correction, correction by total cholesterol only or use of different statistical models. ..
  4. Addae C, Cheng H, Martinez Ceballos E. Effect of the environmental pollutant hexachlorobenzene (HCB) on the neuronal differentiation of mouse embryonic stem cells. Int J Environ Res Public Health. 2013;10:5244-56 pubmed publisher
    ..In this work, we have examined the effect of hexachlorobenzene (HCB), a persistent and bioaccumulative environmental pollutant, on the function and morphology of GABAergic ..
  5. Bradman A, Schwartz J, Fenster L, Barr D, Holland N, Eskenazi B. Factors predicting organochlorine pesticide levels in pregnant Latina women living in a United States agricultural area. J Expo Sci Environ Epidemiol. 2007;17:388-99 pubmed
    ..dichlorodiphenyltrichloroethane (DDT), lindane (99% pure gamma-hexachlorocyclohexane (gamma-HCH)), hexachlorobenzene (HCB) - occurs on a limited basis...
  6. Gasull M, Bosch de Basea M, Puigdomenech E, Pumarega J, Porta M. Empirical analyses of the influence of diet on human concentrations of persistent organic pollutants: a systematic review of all studies conducted in Spain. Environ Int. 2011;37:1226-35 pubmed publisher
    ..As in a few other countries, in Spain food consumption is increasingly analyzed as a major determinant of human POP intake. ..
  7. Ribas Fito N, Grimalt J, Marco E, Sala M, Mazón C, Sunyer J. Breastfeeding and concentrations of HCB and p,p'-DDE at the age of 1 year. Environ Res. 2005;98:8-13 pubmed
    Exposure to organochlorine compounds (OCs) occurs both in utero and through breastfeeding. Levels of hexachlorobenzene (HCB) in the cord serum of newborns from a population located in the vicinity of an electrochemical factory in Spain ..
  8. Bhatnagar V, Kashyap R, Zaidi S, Kulkarni P, Saiyed H. Levels of DDT, HCH, and HCB residues in human blood in Ahmedabad, India. Bull Environ Contam Toxicol. 2004;72:261-5 pubmed
  9. Kim K, Lee S, Kim K, Shim W, Hong S, Choi K, et al. Survey on organochlorine pesticides, PCDD/Fs, dioxin-like PCBs and HCB in sediments from the Han river, Korea. Chemosphere. 2009;75:580-7 pubmed publisher
    ..The principal source of HCB, DL-PCBs and PCDD/Fs was identified as a deposition in this study. For the DL-PCBs, it was also shown that commercial PCBs product (Kanechlor 500 and/or Aroclor 1254) plays a role as a source in sediment. ..

More Information

Publications62

  1. Li T, Yuan S, Wan J, Lin L, Long H, Wu X, et al. Pilot-scale electrokinetic movement of HCB and Zn in real contaminated sediments enhanced with hydroxypropyl-beta-cyclodextrin. Chemosphere. 2009;76:1226-32 pubmed publisher
    ..with the efficiency of a pilot-scale electrokinetic (EK) treatment on real aged sediments contaminated with hexachlorobenzene (HCB) and Zn. A total of 0...
  2. Smink A, Ribas Fito N, Garcia R, Torrent M, Mendez M, Grimalt J, et al. Exposure to hexachlorobenzene during pregnancy increases the risk of overweight in children aged 6 years. Acta Paediatr. 2008;97:1465-9 pubmed publisher
    To determine whether prenatal exposure to hexachlorobenzene (HCB) has potential adverse effects on child's weight and body mass index (BMI) in a general population with no local pollution sources...
  3. Song S, Xu Y, Zhou B. Effects of hexachlorobenzene on antioxidant status of liver and brain of common carp (Cyprinus carpio). Chemosphere. 2006;65:699-706 pubmed
    b>Hexachlorobenzene (HCB)-induced oxidative damages have been published in rats while the effects have not yet been reported in fishes...
  4. Chevrier J, Eskenazi B, Holland N, Bradman A, Barr D. Effects of exposure to polychlorinated biphenyls and organochlorine pesticides on thyroid function during pregnancy. Am J Epidemiol. 2008;168:298-310 pubmed publisher
    ..the authors' objective was to determine whether serum concentrations of polychlorinated biphenyls (PCBs), hexachlorobenzene, p,p'-dichlorodiphenyl trichloroethane (DDT), o,p'-DDT, and p,p'-dichlorodiphenyl dichloroethylene (DDE) are ..
  5. Mundy L, Jones S, Crump D, Hervé J, Konstantinov A, Utley F, et al. Highly purified hexachlorobenzene induces cytochrome P4501A in primary cultures of chicken embryo hepatocytes. Toxicol Appl Pharmacol. 2010;248:185-93 pubmed publisher
    Some uncertainty exists regarding the purity of hexachlorobenzene (HCB) used in past toxicity studies...
  6. Pontillo C, Garcia M, Peña D, Cocca C, Chiappini F, Alvarez L, et al. Activation of c-Src/HER1/STAT5b and HER1/ERK1/2 signaling pathways and cell migration by hexachlorobenzene in MDA-MB-231 human breast cancer cell line. Toxicol Sci. 2011;120:284-96 pubmed publisher
    b>Hexachlorobenzene (HCB) is a widespread environmental pollutant. It is a dioxin-like compound and a weak ligand of the aryl hydrocarbon receptor (AhR) protein...
  7. Reed L, Buchner V, Tchounwou P. Environmental toxicology and health effects associated with hexachlorobenzene exposure. Rev Environ Health. 2007;22:213-43 pubmed
    The synthetic industrial chemical hexachlorobenzene (HCB) is a white crystalline solid compound. The substance is a bioaccumulative, persistent, and toxic pollutant. Historically HCB was commonly used as a pesticide and fungicide...
  8. Meeker J, Altshul L, Hauser R. Serum PCBs, p,p'-DDE and HCB predict thyroid hormone levels in men. Environ Res. 2007;104:296-304 pubmed
    ..levels of 57 PCB congeners, dichlorodiphenyldichloroethylene (p,p(')-DDE, a stable metabolite of DDT), and hexachlorobenzene (HCB), as well as free T(4), total T(3), and TSH, in 341 adult men recruited from an infertility clinic from ..
  9. Erdinger L, Eckl P, Ingel F, Khussainova S, Utegenova E, Mann V, et al. The Aral Sea disaster--human biomonitoring of Hg, As, HCB, DDE, and PCBs in children living in Aralsk-and Akchi, Kazakhstan. Int J Hyg Environ Health. 2004;207:541-7 pubmed
    ..HCB and PCBs levels differed significantly between both Kazakh groups. However, concentrations of these compounds were lower than German reference values and there was no significant difference to samples from Mannheim children. ..
  10. Langer P, Kocan A, Drobna B, Susienkova K, Radikova Z, Huckova M, et al. Blood testosterone in middle aged males heavily exposed to endocrine disruptors is decreasing more with HCB and p,p'-DDE related to BMI and lipids, but not with ?15PCBs. Endocr Regul. 2012;46:51-9 pubmed
    ..41-55 years) males heavily exposed to POPs the levels of 15 polychlorinated biphenyl congeners (?15PCBs), hexachlorobenzene (HCB), and dichlorodiethyl-dichloroethylene (p,p'-DDE) were measured by gas chromatography/mass spectrometry ..
  11. Barber J, Sweetman A, van Wijk D, Jones K. Hexachlorobenzene in the global environment: emissions, levels, distribution, trends and processes. Sci Total Environ. 2005;349:1-44 pubmed
    b>Hexachlorobenzene (HCB) is considered here as a 'model persistent organic pollutant...
  12. Alvarez Pedrerol M, Ribas Fito N, Torrent M, Carrizo D, Grimalt J, Sunyer J. Effects of PCBs, p,p'-DDT, p,p'-DDE, HCB and beta-HCH on thyroid function in preschool children. Occup Environ Med. 2008;65:452-7 pubmed
    ..This study suggests that even at background levels of exposure, OCs may affect the thyroid system, particularly total T3 levels. ..
  13. Ferguson K, Hauser R, Altshul L, Meeker J. Serum concentrations of p, p'-DDE, HCB, PCBs and reproductive hormones among men of reproductive age. Reprod Toxicol. 2012;34:429-35 pubmed publisher
    ..We investigated the association of PCBs, hexachlorobenzene (HCB) and p, p'-DDE with serum sex hormones in 341 adult men from a US infertility clinic with exposure ..
  14. Randi A, Sanchez M, Alvarez L, Cardozo J, Pontillo C, Kleiman de Pisarev D. Hexachlorobenzene triggers AhR translocation to the nucleus, c-Src activation and EGFR transactivation in rat liver. Toxicol Lett. 2008;177:116-22 pubmed publisher
    b>Hexachlorobenzene (HCB) is a widespread environmental pollutant. It has some properties that are typical for dioxin-like compounds that act mainly through the aryl hydrocarbon receptor (AhR) protein...
  15. Randi A, Cocca C, Carbone V, Nuñez M, Croci M, Gutierrez A, et al. Hexachlorobenzene is a tumor co-carcinogen and induces alterations in insulin-growth factors signaling pathway in the rat mammary gland. Toxicol Sci. 2006;89:83-92 pubmed
    b>Hexachlorobenzene (HCB) is a widespread environmental pollutant. Controversy still exists about the breast carcinogenic properties of organochlorines in humans...
  16. Bergknut M, Laudon H, Wiberg K. Dioxins, PCBs, and HCB in soil and peat profiles from a pristine boreal catchment. Environ Pollut. 2010;158:2518-25 pubmed publisher
    ..The calculated net vertical transport differed between surface layers (0.3%) and deeper soils (8.0%), suggesting that vertical transport conditions and processes differ in the deeper layers compared to the surface layers. ..
  17. Grimalt J, Carrizo D, Garí M, Font Ribera L, Ribas Fito N, Torrent M, et al. An evaluation of the sexual differences in the accumulation of organochlorine compounds in children at birth and at the age of 4 years. Environ Res. 2010;110:244-50 pubmed publisher
    ..birth 1997-1998) of children at birth and at 4 years of age; the study has shown that the concentrations of hexachlorobenzene (HCB), 4,4'-DDE, 4,4'-DDT, polychlorobiphenyl (PCB) congeners #153, #138 and #180 and total PCBs in sera ..
  18. Eggesbø M, Stigum H, Longnecker M, Polder A, Aldrin M, Basso O, et al. Levels of hexachlorobenzene (HCB) in breast milk in relation to birth weight in a Norwegian cohort. Environ Res. 2009;109:559-66 pubmed publisher
    b>Hexachlorobenzene (HCB) is a ubiquitous environmental contaminant that, even at low doses, causes destruction of ovarian primordial germ cells in experimental studies...
  19. Valkusz Z, Nagyeri G, Radacs M, Ocskó T, Hausinger P, Laszlo M, et al. Further analysis of behavioral and endocrine consequences of chronic exposure of male Wistar rats to subtoxic doses of endocrine disruptor chlorobenzenes. Physiol Behav. 2011;103:421-30 pubmed publisher
    ..Adult, male Wistar rats were exposed daily to 0.1 ?g/kg of 1,2,4-trichlorobenzene and hexachlorobenzene via a stomach tube for 30, 60 or 90 days, after which anxiety-related and aggressive behavioral elements ..
  20. Lopez Espinosa M, Vizcaino E, Murcia M, Fuentes V, Garcia A, Rebagliato M, et al. Prenatal exposure to organochlorine compounds and neonatal thyroid stimulating hormone levels. J Expo Sci Environ Epidemiol. 2010;20:579-88 pubmed publisher
    ..4,4'-DDT), 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene (4,4'-DDE), ?-hexachlorocyclohexane (?-HCH), hexachlorobenzene (HCB), four individual polychlorobiphenyl (PCB) congeners (118, 138, 153, and 180), and their sum, with ..
  21. Arrebola J, Martin Olmedo P, Fernandez M, Sanchez Cantalejo E, Jimenez Rios J, Torne P, et al. Predictors of concentrations of hexachlorobenzene in human adipose tissue: a multivariate analysis by gender in Southern Spain. Environ Int. 2009;35:27-32 pubmed publisher
    b>Hexachlorobenzene (HCB) was measured in adipose tissue intraoperatively collected from 387 subjects over 16 years old undergoing surgery in two hospitals in Granada (Southern Spain). HCB was quantified in 90.7% of subjects...
  22. Ennaceur S, Ridha D, Marcos R. Genotoxicity of the organochlorine pesticides 1,1-dichloro-2,2- bis(p-chlorophenyl)ethylene (DDE) and hexachlorobenzene (HCB) in cultured human lymphocytes. Chemosphere. 2008;71:1335-9 pubmed publisher
    ..DDE), which is a metabolite of dichlorobiphenyltrichloroetane (DDT), and hexachlorobenzene (HCB), which are organochlorine pesticides have been evaluated in vitro by using human lymphocytes as test ..
  23. Herrero C, Ozalla D, Sala M, Otero R, Santiago Silva M, Lecha M, et al. Urinary porphyrin excretion in a human population highly exposed to hexachlorobenzene. Arch Dermatol. 1999;135:400-4 pubmed
    Data from an epidemic reported in Turkey (1955-1959) is the only information about the relationship between hexachlorobenzene (HCB) intake and porphyria cutanea tarda in humans...
  24. Zheng T, Holford T, Mayne S, Tessari J, Owens P, Zahm S, et al. Environmental exposure to hexachlorobenzene (HCB) and risk of female breast cancer in Connecticut. Cancer Epidemiol Biomarkers Prev. 1999;8:407-11 pubmed
    Earlier studies have provided inconclusive results relating hexachlorobenzene (HCB), an organochlorine fungicide, to female breast cancer risk...
  25. Daniel V, Huber W, Bauer K, Suesal C, Conradt C, Opelz G. Associations of blood levels of PCB, HCHS, and HCB with numbers of lymphocyte subpopulations, in vitro lymphocyte response, plasma cytokine levels, and immunoglobulin autoantibodies. Environ Health Perspect. 2001;109:173-8 pubmed
    ..beta, and -[gamma] (HCH-[alpha], -beta, and -[gamma]), polychlorinated biphenyls (PCBs), and hexachlorobenzene (HCB) are widely distributed industrial chemicals...
  26. Mazzetti M, Taira M, Lelli S, Dascal E, Basabe J, de Viale L. Hexachlorobenzene impairs glucose metabolism in a rat model of porphyria cutanea tarda: a mechanistic approach. Arch Toxicol. 2004;78:25-33 pubmed
    ..These results contribute to our understanding of the protective and modulatory effect that diets rich in carbohydrates have in hepatic porphyria disease. ..
  27. Meijer S, Ockenden W, Sweetman A, Breivik K, Grimalt J, Jones K. Global distribution and budget of PCBs and HCB in background surface soils: implications for sources and environmental processes. Environ Sci Technol. 2003;37:667-72 pubmed
    This paper presents data from a survey of polychlorinated biphenyls (PCBs) and hexachlorobenzene (HCB) concentrations in 191 global background surface (0-5 cm) soils...
  28. Salmon M, Madanagopal S, Blando R, Berner J, Williams K. Effects of hexachlorobenzene on embryonic mammalian cells. Toxicol In Vitro. 2002;16:539-48 pubmed
    b>Hexachlorobenzene (HCB) is a persistent organic pollutant that has been found to be bioaccumulating in several Arctic regions of the world...
  29. Karmaus W, Kuehr J, Kruse H. Infections and atopic disorders in childhood and organochlorine exposure. Arch Environ Health. 2001;56:485-92 pubmed
    ..However, for the combined effect of dichlorodiphenyldichloroethene with polychlorinated biphenyls or hexachlorobenzene, a significantly increased relative risk (odds ratios = 3.70 and 2...
  30. Plante I, Charbonneau M, Cyr D. Decreased gap junctional intercellular communication in hexachlorobenzene-induced gender-specific hepatic tumor formation in the rat. Carcinogenesis. 2002;23:1243-9 pubmed
    b>Hexachlorobenzene (HCB), an epigenetic carcinogen, HCB induces the formation of liver tumors in female rats, whereas only a small percentage of males are responsive...
  31. Jarrell J, Gocmen A, Foster W, Brant R, Chan S, Sevcik M. Evaluation of reproductive outcomes in women inadvertently exposed to hexachlorobenzene in southeastern Turkey in the 1950s. Reprod Toxicol. 1998;12:469-76 pubmed
    In southeastern Turkey during the period of 1955-57, women were accidentally exposed to the fungicide hexachlorobenzene (HCB) after eating contaminated seed grain and developed porphyria cutanea tarda (PCT)...
  32. O Hara T, Krahn M, Boyd D, Becker P, Philo L. Organochlorine contaminant levels in Eskimo harvested bowhead whales of arctic Alaska. J Wildl Dis. 1999;35:741-52 pubmed
    ..For female bowhead whales, hexachlorobenzene and lipid levels decreased and other OC levels did not change significantly with increasing length...
  33. Korrick S, Altshul L, Tolbert P, Burse V, Needham L, Monson R. Measurement of PCBs, DDE, and hexachlorobenzene in cord blood from infants born in towns adjacent to a PCB-contaminated waste site. J Expo Anal Environ Epidemiol. 2000;10:743-54 pubmed
    ..of common contaminants--polychlorinated biphenyls (PCBs), dichlorodiphenyl dichloroethene (pp'-DDE) and hexachlorobenzene (HCB)--in umbilical cord blood...
  34. Sala M, Ribas Fito N, Cardo E, De Muga M, Marco E, Mazon C, et al. Levels of hexachlorobenzene and other organochlorine compounds in cord blood: exposure across placenta. Chemosphere. 2001;43:895-901 pubmed
    b>Hexachlorobenzene (HCB) is an organochlorine compound widespread in the environment, highly lipophilic, that accumulates in biological systems. It has been suggested that it should be classified as a dioxin-like compound...
  35. Karmaus W, DeKoning E, Kruse H, Witten J, Osius N. Early childhood determinants of organochlorine concentrations in school-aged children. Pediatr Res. 2001;50:331-6 pubmed
    ..and smoking contribute to the variation of organochlorine compounds (OC: dichlorodiphenyldichloroethene, hexachlorobenzene, beta-hexachlorocyclohexane, and the sum of polychlorinated biphenyls including the congeners 101, 118, 138, ..
  36. Fitzgerald E, Hwang S, Deres D, Bush B, Cook K, Worswick P. The association between local fish consumption and DDE, mirex, and HCB concentrations in the breast milk of Mohawk women at Akwesasne. J Expo Anal Environ Epidemiol. 2001;11:381-8 pubmed
    ..consumption of local fish contaminated with p,p'-dichlorodiphenyl dichloroethylene (p,p'-DDE), mirex, and hexachlorobenzene (HCB) has impacted the concentrations of these compounds in the milk of nursing Mohawk women residing along ..
  37. Ozalla D, Herrero C, Ribas Fito N, To Figueras J, Toll A, Sala M, et al. Evaluation of urinary porphyrin excretion in neonates born to mothers exposed to airborne hexachlorobenzene. Environ Health Perspect. 2002;110:205-9 pubmed
    The existence of a link between hexachlorobenzene (HCB) and porphyria cutanea tarda has been known for a long time...
  38. Booij K, Hoedemaker J, Bakker J. Dissolved PCBs, PAHs, and HCB in pore waters and overlying waters of contaminated harbor sediments. Environ Sci Technol. 2003;37:4213-20 pubmed
    ..of polychlorinated biphenyls (PCBs), polyaromatic hydrocarbons (PAHs), pentachlorobenzene, and hexachlorobenzene (HCB) were determined by exposing low-density polyethylene (LDPE) strips to the pore waters and the ..
  39. Gao X, Wang W, Liu X. Dechlorination reaction of hexachlorobenzene with calcium oxide at 300-400 degrees C. J Hazard Mater. 2009;169:279-84 pubmed publisher
    b>Hexachlorobenzene (HCB) was thermally treated with calcium oxide (CaO) at 300-400 degrees C. Analyses of chloride ions and residual HCB confirmed that a dechlorination reaction had occurred...
  40. Liu G, Cai M, Zheng M, Nie Z, Liu W, Lv P, et al. Levels and profiles of unintentionally produced persistent organic pollutants in surface soils from Shanxi province, China. Bull Environ Contam Toxicol. 2011;86:535-8 pubmed publisher
    ..dibenzo-p-dioxins, polychlorinated dibenzofurans, polychlorinated biphenyls, polychlorinated naphthalenes, hexachlorobenzene and pentachlorobenzene in soils collected from Shanxi province, China were determined...
  41. Dallaire R, Muckle G, Dewailly E, Jacobson S, Jacobson J, Sandanger T, et al. Thyroid hormone levels of pregnant inuit women and their infants exposed to environmental contaminants. Environ Health Perspect. 2009;117:1014-20 pubmed publisher
    ..of several contaminants [PCB-153, hydroxylated metabolites of PCBs (HO-PCBs), pentachlorophenol (PCP) and hexachlorobenzene (HCB)] in maternal plasma at delivery (n = 120), in umbilical cord plasma (n = 95), and in infant plasma at ..
  42. Josefsson S, Karlsson O, Malmaeus J, Cornelissen G, Wiberg K. Structure-related distribution of PCDD/Fs, PCBs and HCB in a river-sea system. Chemosphere. 2011;83:85-94 pubmed publisher
    ..The PCDD/F concentration in the sea decreased to one third in May, likely connected to the increased vertical flux of particles during the spring bloom. ..
  43. Charlier C, Foidart J, Pitance F, Herman P, Gaspard U, Meurisse M, et al. Environmental dichlorodiphenyltrichlorethane or hexachlorobenzene exposure and breast cancer: is there a risk?. Clin Chem Lab Med. 2004;42:222-7 pubmed
    ..study, we have compared the serum levels of p,p'-1,1-dichloro-2, 2-bis (4-chlorophenyl) ethylene (DDE) and hexachlorobenzene (HCB) in 231 women at the time of breast cancer discovery and in 290 age-matched healthy controls...
  44. Miyoshi K, Nishio T, Yasuhara A, Morita M, Shibamoto T. Detoxification of hexachlorobenzene by dechlorination with potassium-sodium alloy. Chemosphere. 2004;55:1439-46 pubmed
    Dechlorination of hexachlorobenzene (HCB) was achieved by a liquid potassium-sodium (K-Na)-alloy. HCB in a cyclohexane/benzene solution (22 mmol/l, 4...
  45. Mast M, Alvarez D, Zaugg S. Deposition and accumulation of airborne organic contaminants in Yosemite National Park, California. Environ Toxicol Chem. 2012;31:524-33 pubmed publisher
    ..and endosulfans and legacy compounds chlordane, dichlorodiphenyltrichloroethane-related compounds, dieldrin, hexachlorobenzene, and polychlorinated biphenyls...
  46. Zuin V, Schellin M, Montero L, Yariwake J, Augusto F, Popp P. Comparison of stir bar sorptive extraction and membrane-assisted solvent extraction as enrichment techniques for the determination of pesticide and benzo[a]pyrene residues in Brazilian sugarcane juice. J Chromatogr A. 2006;1114:180-7 pubmed
    ..A comparison of the results of the pesticide and benzo[a]pyrene residues at microgL(-1) level obtained by the two methods showed good agreement. ..
  47. Chai Y, Qiu X, Davis J, Budinsky R, Bartels M, Saghir S. Effects of black carbon and montmorillonite clay on multiphasic hexachlorobenzene desorption from sediments. Chemosphere. 2007;69:1204-12 pubmed
    The desorption kinetics of hexachlorobenzene (HCB) in four freshly spiked artificial sediments were determined using a polymeric adsorbent Tenax-mediated desorption...
  48. García M, Peña D, Alvarez L, Cocca C, Pontillo C, Bergoc R, et al. Hexachlorobenzene induces cell proliferation and IGF-I signaling pathway in an estrogen receptor alpha-dependent manner in MCF-7 breast cancer cell line. Toxicol Lett. 2010;192:195-205 pubmed publisher
    b>Hexachlorobenzene (HCB) is an organochlorine pesticide widely distributed in the biosphere. ERalpha regulates the expression of genes involved in growth and development, and plays an important role in breast cancer...
  49. Malarvannan G, Kunisue T, Isobe T, Sudaryanto A, Takahashi S, Prudente M, et al. Organohalogen compounds in human breast milk from mothers living in Payatas and Malate, the Philippines: levels, accumulation kinetics and infant health risk. Environ Pollut. 2009;157:1924-32 pubmed publisher
    ..A few individuals accumulated CHLs close to or even higher than the tolerable daily intake guidelines proposed by Health Canada. ..
  50. McGovern V. Hexachlorobenzene exposure: widespread toxicant produces pervasive effects. Environ Health Perspect. 2004;112:A416 pubmed
  51. Liu C, Jiang X. [Effect of composting organic fertilizer supplies on hexachlorobenzene dechlorination in paddy soils]. Huan Jing Ke Xue. 2013;34:1583-9 pubmed
    ..The objective of this research was to evaluate the reductive dechlorination of hexachlorobenzene (HCB) as affected by organic fertilizer supplies in planted paddy soils, and to analyze the relationship ..
  52. Liu T, Chen Z, Shen Y, Gan L, Cao L, Lv Z. Monitoring bioaccumulation and toxic effects of hexachlorobenzene using the polyurethane foam unit method in the microbial communities of the Fuhe River, Wuhan. J Environ Sci (China). 2007;19:738-44 pubmed
    b>Hexachlorobenzene (HCB) is a chlorinated aromatic hydrocarbon that was widely used for seed dressing in prevention of fungal growth on crops, and also as a component of fireworks, ammunition, and synthetic rubbers...
  53. Porta M, Gasull M, Puigdomenech E, Garí M, Bosch de Basea M, Guillen M, et al. Distribution of blood concentrations of persistent organic pollutants in a representative sample of the population of Catalonia. Environ Int. 2010;36:655-64 pubmed publisher
    ..dichlorodiphenyldichloroethane (p,p'-DDE), polychlorinated biphenyls (PCBs) congeners 118, 138, 153 and 180, hexachlorobenzene (HCB) and beta-hexachlorocyclohexane (beta-HCH) in more than 85% of the subjects...