Summary: A two carbon alkane with the formula H3C-CH3.

Top Publications

  1. Hong S, Gil H, Yang J, Lee E, Na J, Seo K, et al. Clinical implications of the ethane in exhaled breath in patients with acute paraquat intoxication. Chest. 2005;128:1506-10 pubmed
    Pulmonary fibrosis due to lipid peroxidation is a major symptom of paraquat intoxication. Ethane in the expired breath (exEth) reflects lipid peroxidation and may be a measure of the damage effected by oxygen radicals in acute lung injury...
  2. Simpson I, Sulbaek Andersen M, Meinardi S, Bruhwiler L, Blake N, Helmig D, et al. Long-term decline of global atmospheric ethane concentrations and implications for methane. Nature. 2012;488:490-4 pubmed publisher
    After methane, ethane is the most abundant hydrocarbon in the remote atmosphere...
  3. Thelen S, Miekisch W, Halmer D, Schubert J, Hering P, Mürtz M. Intercomparison of infrared cavity leak-out spectroscopy and gas chromatography-flame ionization for trace analysis of ethane. Anal Chem. 2008;80:2768-73 pubmed publisher
    Comparison of two different methods for the measurement of ethane at the parts-per-billion (ppb) level is reported...
  4. Meinhold P, Peters M, Chen M, Takahashi K, Arnold F. Direct conversion of ethane to ethanol by engineered cytochrome P450 BM3. Chembiochem. 2005;6:1765-8 pubmed
  5. von Basum G, Dahnke H, Halmer D, Hering P, Mürtz M. Online recording of ethane traces in human breath via infrared laser spectroscopy. J Appl Physiol (1985). 2003;95:2583-90 pubmed
    A method is described for rapidly measuring the ethane concentration in exhaled human breath. Ethane is considered a volatile marker for lipid peroxidation...
  6. Gorham K, Sulbaek Andersen M, Meinardi S, Delfino R, Staimer N, Tjoa T, et al. Ethane and n-pentane in exhaled breath are biomarkers of exposure not effect. Biomarkers. 2009;14:17-25 pubmed publisher
    The relationship of exhaled ethane and n-pentane to exhaled NO, carbonylated proteins, and indoor/outdoor atmospheric pollutants were examined in order to evaluate ethane and n-pentane as potential markers of airway inflammation and/or ..
  7. Lärstad M, Loh C, Ljungkvist G, Olin A, Toren K. Determination of ethane, pentane and isoprene in exhaled air using a multi-bed adsorbent and end-cut gas-solid chromatography. Analyst. 2002;127:1440-5 pubmed
    A method for the determination of exhaled ethane, pentane and isoprene was developed and validated...
  8. Xu F, Bell S, Lednik J, Insley A, Rao Z, Wong L. The heme monooxygenase cytochrome P450cam can be engineered to oxidize ethane to ethanol. Angew Chem Int Ed Engl. 2005;44:4029-32 pubmed
  9. Ross B, McKenzie I, Glen I, Bennett C. Increased levels of ethane, a non-invasive marker of n-3 fatty acid oxidation, in breath of children with attention deficit hyperactivity disorder. Nutr Neurosci. 2003;6:277-81 pubmed
    ..We have measured exhalant ethane levels, a non-invasive measure of oxidative damage to n-3 fatty acids, to probe biochemical alterations in ADHD...

More Information


  1. Cope K, Solga S, Hummers L, Wigley F, Diehl A, Risby T. Abnormal exhaled ethane concentrations in scleroderma. Biomarkers. 2006;11:70-84 pubmed
    ..Therefore, it was postulated that patients with scleroderma would have abnormally high breath ethane concentrations, which is a volatile product of free-radical-mediated lipid peroxidation, compared with a group of ..
  2. Peterson R, Nucci N, Wand A. Modification of encapsulation pressure of reverse micelles in liquid ethane. J Magn Reson. 2011;212:229-33 pubmed publisher
    ..Liquid ethane is of sufficiently low viscosity at pressures below 5000 psi to offer a significant advantage...
  3. Kazansky V, Subbotina I, Rane N, van Santen R, Hensen E. On two alternative mechanisms of ethane activation over ZSM-5 zeolite modified by Zn2+ and Ga1+ cations. Phys Chem Chem Phys. 2005;7:3088-92 pubmed
    The activation of ethane over zinc- and gallium-modified HZSM-5 dehydrogenation catalysts was studied by diffuse reflectance infrared spectroscopy...
  4. Kida M, Jin Y, Takahashi N, Nagao J, Narita H. Dissociation behavior of methane--ethane mixed gas hydrate coexisting structures I and II. J Phys Chem A. 2010;114:9456-61 pubmed publisher
    Dissociation behavior of methane-ethane mixed gas hydrate coexisting structures I and II at constant temperatures less than 223 K was studied with use of powder X-ray diffraction and solid-state (13)C NMR techniques...
  5. Redmond M, Valentine D, Sessions A. Identification of novel methane-, ethane-, and propane-oxidizing bacteria at marine hydrocarbon seeps by stable isotope probing. Appl Environ Microbiol. 2010;76:6412-22 pubmed publisher
    ..After incubating sediment with (13)C-labeled methane, ethane, or propane, we confirmed the incorporation of (13)C into fatty acids and DNA...
  6. Santosa I, Ram P, Boamfa E, Laarhoven L, Reuss J, Jackson M, et al. Patterns of peroxidative ethane emission from submerged rice seedlings indicate that damage from reactive oxygen species takes place during submergence and is not necessarily a post-anoxic phenomenon. Planta. 2007;226:193-202 pubmed
    Using ethane as a marker for peroxidative damage to membranes by reactive oxygen species (ROS) we examined the injury of rice seedlings during submergence in the dark...
  7. Wyse C, Cathcart A, Sutherland R, Ward S, McMillan L, Gibson G, et al. Effect of maximal dynamic exercise on exhaled ethane and carbon monoxide levels in human, equine, and canine athletes. Comp Biochem Physiol A Mol Integr Physiol. 2005;141:239-46 pubmed
    ..Breath ethane is a product of free radical-mediated oxidation of cell membrane lipids and is considered to be a reliable marker ..
  8. Lärstad M, Toren K, Bake B, Olin A. Determination of ethane, pentane and isoprene in exhaled air--effects of breath-holding, flow rate and purified air. Acta Physiol (Oxf). 2007;189:87-98 pubmed
    Exhaled ethane, pentane and isoprene have been proposed as biomarkers of oxidative stress...
  9. Murshed M, Schmidt B, Kuhs W. Kinetics of methane-ethane gas replacement in clathrate-hydrates studied by time-resolved neutron diffraction and Raman spectroscopy. J Phys Chem A. 2010;114:247-55 pubmed publisher
    ..Deuterated ethane structure type I (C(2)H(6) sI) hydrates were transformed in a closed volume into methane-ethane mixed structure ..
  10. Hardy M, Margitich D, Ackerman L, Smith R. The subchronic oral toxicity of ethane, 1,2-bis(pentabromophenyl) (Saytex 8010) in rats. Int J Toxicol. 2002;21:165-70 pubmed
    b>Ethane, 1,2-bis(pentabromophenyl) (EBP; CAS no...
  11. Aydin M, Verhulst K, Saltzman E, Battle M, Montzka S, Blake D, et al. Recent decreases in fossil-fuel emissions of ethane and methane derived from firn air. Nature. 2011;476:198-201 pubmed publisher
    Methane and ethane are the most abundant hydrocarbons in the atmosphere and they affect both atmospheric chemistry and climate...
  12. Murshed M, Kuhs W. Kinetic studies of methane-ethane mixed gas hydrates by neutron diffraction and Raman spectroscopy. J Phys Chem B. 2009;113:5172-80 pubmed publisher
    ..The final persistence of a small portion of sII hydrate points to a miscibility gap between CH(4)-rich sI and C(2)H(6)-rich sII hydrates. ..
  13. Puri B, Ross B, Treasaden I. Increased levels of ethane, a non-invasive, quantitative, direct marker of n-3 lipid peroxidation, in the breath of patients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32:858-62 pubmed publisher
    This study directly assessed whether there was a change in the level of exhaled ethane, which provides a non-invasive, quantitative, direct measure of n-3 lipid peroxidation, in the breath of patients with schizophrenia...
  14. Handelman G, Rosales L, Barbato D, Luscher J, Adhikarla R, Nicolosi R, et al. Breath ethane in dialysis patients and control subjects. Free Radic Biol Med. 2003;35:17-23 pubmed
    ..We undertook to measure ethane, a major breath hydrocarbon, in 15 control subjects, 13 patients on peritoneal dialysis (PD), and 35 patients on ..
  15. Puri B, Treasaden I, Cocchi M, Tsaluchidu S, Tonello L, Ross B. A comparison of oxidative stress in smokers and non-smokers: an in vivo human quantitative study of n-3 lipid peroxidation. BMC Psychiatry. 2008;8 Suppl 1:S4 pubmed publisher of the relationship of smoking in humans to the level of n-3 lipid peroxidation indexed by the level of ethane in exhaled breath. Samples of alveolar air were obtained from 11 smokers and 18 non-smokers...
  16. Parameswaran K, Rosen D, Allen M, Ganz A, Risby T. Off-axis integrated cavity output spectroscopy with a mid-infrared interband cascade laser for real-time breath ethane measurements. Appl Opt. 2009;48:B73-9 pubmed
    ..b>Ethane is a breath biomarker of lipid peroxidation initiated by reactive oxygen species...
  17. Burns C, Wagner B. Heightened susceptibility of fish oil polyunsaturate-enriched neoplastic cells to ethane generation during lipid peroxidation. J Lipid Res. 1991;32:79-87 pubmed
    ..There was considerable generation of ethane, and this was dependent on cell number and Fe2+ concentration; it was eliminated by antioxidants and augmented by ..
  18. Skeldon K, Gibson G, Wyse C, McMillan L, Monk S, Longbottom C, et al. Development of high-resolution real-time sub-ppb ethane spectroscopy and some pilot studies in life science. Appl Opt. 2005;44:4712-21 pubmed
    We describe a high-resolution real-time spectroscopy system targeted to ethane gas with sensitivity > or = 70 ppt and response time from > or = 0.7 s...
  19. Dale O, Bergum H, Lund T, Nilsen T, Aadahl P, Stenseth R. A validated method for rapid analysis of ethane in breath and its application in kinetic studies in human volunteers. Free Radic Res. 2003;37:815-21 pubmed
    Oxidative stress may initiate lipid peroxidation that generates ethane. Ethane, at low concentrations, is eliminated by pulmonary exhalation...
  20. Peres C, Gomes da Silva M, Barreiros S. Water activity effects on geranyl acetate synthesis catalyzed by novozym in supercritical ethane and in supercritical carbon dioxide. J Agric Food Chem. 2003;51:1884-8 pubmed
    The esterification reaction of geraniol with acetic acid catalyzed by Novozym was studied in supercritical ethane (sc-ethane) and in supercritical carbon dioxide (sc-CO(2))...
  21. Kanoh S, Kobayashi H, Motoyoshi K. Exhaled ethane: an in vivo biomarker of lipid peroxidation in interstitial lung diseases. Chest. 2005;128:2387-92 pubmed
    Oxidative stress plays a role in the pathogenesis and progression of interstitial lung disease (ILD). Exhaled ethane is a product of lipid peroxidation that has been proposed as a biomarker of oxidative stress in vivo...
  22. Peterson R, Lefebvre B, Wand A. High-resolution NMR studies of encapsulated proteins in liquid ethane. J Am Chem Soc. 2005;127:10176-7 pubmed
    ..we present the encapsulation of proteins with high structural fidelity within reverse micelles dissolved in liquid ethane. The addition of appropriate cosurfactants can significantly reduce the pressure required for successful ..
  23. Hinrichs K, Hayes J, Bach W, Spivack A, Hmelo L, Holm N, et al. Biological formation of ethane and propane in the deep marine subsurface. Proc Natl Acad Sci U S A. 2006;103:14684-9 pubmed
    Concentrations and isotopic compositions of ethane and propane in cold, deeply buried sediments from the southeastern Pacific are best explained by microbial production of these gases in situ...
  24. Skeldon K, McMillan L, Wyse C, Monk S, Gibson G, Patterson C, et al. Application of laser spectroscopy for measurement of exhaled ethane in patients with lung cancer. Respir Med. 2006;100:300-6 pubmed
    There is increasing interest in ethane (C(2)H(6)) in exhaled breath as a non-invasive marker of oxidative stress (OS) and thereby a potential indicator of disease...
  25. Nose K, Nunome Y, Kondo T, Araki S, Tsuda T. Identification of gas emanated from human skin: methane, ethylene, and ethane. Anal Sci. 2005;21:625-8 pubmed
    We investigated whether methane, ethylene and ethane gas can be detected in gas emanating from human skin, which is called skin gas...
  26. Mo Y, Gao J. Theoretical analysis of the rotational barrier of ethane. Acc Chem Res. 2007;40:113-9 pubmed
    The understanding of the ethane rotation barrier is fundamental for structural theory and the conformational analysis of organic molecules and requires a consistent theoretical model to differentiate the steric and hyperconjugation ..
  27. Habib M, Tank L, Lane L, Garewal H. Effect of vitamin E on exhaled ethane in cigarette smokers. Chest. 1999;115:684-90 pubmed
    ..Vitamin E was administered to smokers to determine if exhaled ethane was reduced and if ethane correlated with measures of lung function...
  28. Xie Y, Cwiertny D. Use of dithionite to extend the reactive lifetime of nanoscale zero-valent iron treatment systems. Environ Sci Technol. 2010;44:8649-8655 pubmed publisher
    ..Multiple dithionite additions further improved pollutant removal, allowing at least a 15-fold increase in Cr(VI) removal [?300 mg of Cr(VI)/g of NZVI] relative to that of as-received NZVI [?20 mg of Cr(VI)/g of NZVI]. ..
  29. Zhou X, Duan Y, Yan S, Liu Z, Zhang C, Yao L, et al. Optical modulation of supramolecular assembly of amphiphilic photochromic diarylethene: from nanofiber to nanosphere. Chem Commun (Camb). 2011;47:6876-8 pubmed publisher
    ..The theoretical calculation and model of the self-assembled nanostructure are presented to illuminate the possible self-assembly mechanism. ..
  30. Manchester M, Hug L, Zarek M, Zila A, Edwards E. Discovery of a trans-dichloroethene-respiring Dehalogenimonas species in the 1,1,2,2-tetrachloroethane-dechlorinating WBC-2 consortium. Appl Environ Microbiol. 2012;78:5280-7 pubmed publisher
    ..grew during hydrogenolysis of tDCE to ethene. This is the first time a genus other than Dehalococcoides has been implicated in dechlorination of tDCE to VC. ..
  31. Scheller S, Goenrich M, Thauer R, Jaun B. Methyl-coenzyme M reductase from methanogenic archaea: isotope effects on label exchange and ethane formation with the homologous substrate ethyl-coenzyme M. J Am Chem Soc. 2013;135:14985-95 pubmed publisher
    ..serves as a homologous substrate for the enzyme methyl-coenzyme M reductase (MCR) resulting in the product ethane instead of methane...
  32. Colacci A, Vaccari M, Perocco P, Da Via C, Silingardi P, Manzini E, et al. Enhancement of BALB/c 3T3 cells transformation by 1,2-dibromoethane promoting effect. Carcinogenesis. 1996;17:225-31 pubmed
    ..Results gave evidence for a promoting role of 1,2-dibromoethane in multistep carcinogenesis, probably responsible for the higher oncogenic ability of this compound with respect to 1,1,2,2-tetrachloroethane. ..
  33. Horrocks S, Jung Y, Huwe J, Harvey R, Ricke S, Carstens G, et al. Effects of short-chain nitrocompounds against Campylobacter jejuni and Campylobacter coli in vitro. J Food Sci. 2007;72:M50-5 pubmed
    ..05) in suspensions with added 2-nitro-l-propanol than in unsupplemented or nitroethane-supplemented suspensions, thus reiterating the superior inhibitory effect of 2-nitro-l-propanol. ..
  34. Aulenta F, Bianchi A, Majone M, Petrangeli Papini M, Potalivo M, Tandoi V. Assessment of natural or enhanced in situ bioremediation at a chlorinated solvent-contaminated aquifer in Italy: a microcosm study. Environ Int. 2005;31:185-90 pubmed
    ..g., lactate or butyrate) and/or through bioaugmentation with a Dehalococcoides-containing culture. ..
  35. Gil F, Pla A, Hernandez A, Mercado J, Méndez F. A fatal case following exposure to zinc chloride and hexachloroethane from a smoke bomb in a fire simulation at a school. Clin Toxicol (Phila). 2008;46:563-5 pubmed publisher
  36. Kuykendall L, Hunter W. Carbohydrate and ethane release with Erwinia carotovora subspecies betavasculorum--induced necrosis. Curr Microbiol. 2008;56:128-33 pubmed
    ..cloacae, was examined using digital analysis of photographic evidence of necrosis as well as for carbohydrate, ethane, and ethylene release compared with uninoculated potato tuber slices...
  37. Itadani A, Sogawa Y, Oda A, Torigoe H, Ohkubo T, Kuroda Y. Further evidence for the existence of a dual-Cu+ site in MFI working as the efficient site for C2H6 adsorption at room temperature. Langmuir. 2013;29:9727-33 pubmed publisher
    ..ions (Cu(+)) formed in a copper-ion-exchanged MFI-type zeolite (CuMFI), functions as the active center for strong ethane (C2H6) adsorption even at room temperature rather than a single-type site composed of a Cu(+) ion...
  38. Govender A, Curulla Ferré D, Pérez Jigato M, Niemantsverdriet H. First-principles elucidation of the surface chemistry of the C(2)H(x) (x = 0-6) adsorbate series on Fe(100). Molecules. 2013;18:3806-24 pubmed publisher
    Ab initio total-energy calculations of the elementary reaction steps leading to acetylene, ethylene and ethane formation and their decomposition on Fe(100) are described...
  39. Yan H, Wang H, Qin X, Liu B, Du J. Ultrasound-assisted dispersive liquid-liquid microextraction for determination of fluoroquinolones in pharmaceutical wastewater. J Pharm Biomed Anal. 2011;54:53-7 pubmed publisher
    ..Under the optimized conditions the enrichment factors for the four fluoroquinolones were ranged from 32 to 134 folds. The presented method was applied for the determination of four fluoroquinolones in pharmaceutical wastewater samples. ..
  40. Upadhyayula S, Bao D, Millare B, Sylvia S, Habib K, Ashraf K, et al. Permanent electric dipole moments of carboxyamides in condensed media: what are the limitations of theory and experiment?. J Phys Chem B. 2011;115:9473-90 pubmed publisher
    ..We showed and discussed alternatives for addressing such discrepancies between theory and experiment. ..
  41. Basu D, Asolekar S. Evaluation of substrate removal kinetics for UASB reactors treating chlorinated ethanes. Environ Sci Pollut Res Int. 2012;19:2419-27 pubmed publisher
  42. Green K, Simpson P, Corkery T, Cifuentes M, Samoc M, Humphrey M. Divergent synthesis of ruthenium alkynyl dendrimers and a two-photon absorption cross-section dendritic effect. Macromol Rapid Commun. 2012;33:573-8 pubmed publisher
  43. Guallar V, Gherman B, Miller W, Lippard S, Friesner R. Dynamics of alkane hydroxylation at the non-heme diiron center in methane monooxygenase. J Am Chem Soc. 2002;124:3377-84 pubmed
    ..simulations have been combined with quantum chemistry calculations to provide detailed modeling of the methane and ethane hydroxylation reactions catalyzed by the hydroxylase enzymes of the soluble methane monooxygenase system...
  44. Wheeler J, Stourman N, Armstrong R, Guengerich F. Conjugation of haloalkanes by bacterial and mammalian glutathione transferases: mono- and vicinal dihaloethanes. Chem Res Toxicol. 2001;14:1107-17 pubmed
    ..Vuilleumier, S., Rose, J. A., Armstrong, R. N., and Guengerich, F. P. (2001) Chem. Res. Toxicol. 14, 1118-1127], indicative of an inherent difference in the catalytic mechanisms of the bacterial and mammalian GSH transferases. ..
  45. Culubret E, Luz M, Amils R, Sanz J. Biodegradation of 1,1,1,2-tetrachloroethane under methanogenic conditions. Water Sci Technol. 2001;44:117-22 pubmed
    ..The primary biodegradation of 1,1,1,2-TeCE to 1,1-DCE is a biotic process mediated by anaerobic bacteria. ..
  46. Božic A, Anderson R, Ricke S, Crandall P, O Bryan C. Comparison of nitroethane, 2-nitro-1-propanol, lauric acid, Lauricidin® and the Hawaiian marine algae, Chaetoceros, for potential broad-spectrum control of anaerobically grown lactic acid bacteria. J Environ Sci Health B. 2012;47:269-74 pubmed publisher
    ..These results suggest potential animal health benefits from supplementing cattle diets with lauric acid or Lauricidin® to improve the health of the rumen and help prevent shedding of human pathogens. ..
  47. Yang J, Zhang L, Liu T, Liu D, Hou Y, Feng H. [Determination of 1, 1-dichloro-l-nitroethane in air of workplaces by gas chromatography]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2011;29:629-31 pubmed
    ..This method could be used to detect 1,1-dichloro-1-nitroethane in air of workplaces. ..
  48. Sada P, Bjoraker G, Jennings D, McCabe G, Romani P. Observations of CH4, C2H6, and C2H2 in the stratosphere of Jupiter. Icarus. 1998;136:192-201 pubmed
    ..used in conjunction with height-dependent mixing ratios of each hydrocarbon to determine global abundances for ethane and acetylene. The resulting mixing ratios are 3.9(+1.9)(-1.3) x 10(-6) for C2H6 (5 mbar pressure level), and 2...
  49. Jackson W, Martino L, Hirsh S, Wrobel J, Pardue J. Application of a dialysis sampler to monitor phytoremediation processes. Environ Monit Assess. 2005;107:155-71 pubmed
    ..included concentrations of chlorinated VOCs, organic acids, chloroacetic acids, Cl-, and dissolved gases (ethane, ethene, CH4, CO2)...
  50. Liu X, Cui P, Song B, Bhadury P, Zhu H, Wang S. Synthesis, structure and antibacterial activity of novel 1-(5-substituted-3-substituted-4,5-dihydropyrazol-1-yl)ethanone oxime ester derivatives. Bioorg Med Chem. 2008;16:4075-82 pubmed publisher
    ..25 and 0.125 microg/mL against S. aureus DNA gyrase, 0.125 and 0.25 microg/mL against E. coli DNA gyrase). On the basis of the biological results, structure-activity relationships are also discussed. ..
  51. Nagatsu A, Sugitani T, Mori Y, Okuyama H, Sakakibara J, Mizukami H. Antioxidants from rape (Brassica campestris vir. Japonica Hara) oil cake. Nat Prod Res. 2004;18:231-9 pubmed
    A simple but novel compound, S-1-methoxy-1-(3,5-dimethoxy-4-hydroxyphenyl)ethane, was isolated as a moderately antioxidative compound from rape (Brassica campestris L. subsp. napus) oil cake together with 5 known compounds...
  52. Zhao L, Zhu G, Zhang D, Di Y, Chen Y, Terasaki O, et al. Synthesis and structural identification of a highly ordered mesoporous organosilica with large cagelike pores. J Phys Chem B. 2005;109:764-8 pubmed
    Using 1,2-bis(trimethoxysilyl)ethane as organosiloxane precursor and a triblock copolymer surfactant, Pluronic F127, as template, a highly ordered mesoporous organosilica with large cagelike pores has been successfully synthesized...
  53. Fux S, Jacob C, Neugebauer J, Visscher L, Reiher M. Accurate frozen-density embedding potentials as a first step towards a subsystem description of covalent bonds. J Chem Phys. 2010;132:164101 pubmed publisher
    ..strength (water dimer and F-H-F(-)), a coordination bond (ammonia borane), and a prototypical covalent bond (ethane)...