caproates

Summary

Summary: Derivatives of caproic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain a carboxy terminated six carbon aliphatic structure.

Top Publications

  1. Jiang Y, Jiang Y, He S, Zhang H, Pan C. Dissipation of diethyl aminoethyl hexanoate (DA-6) residues in pakchoi, cotton crops and soil. Bull Environ Contam Toxicol. 2012;88:533-7 pubmed publisher
    ..At harvest, no detectable residues (<LOD) were found in cotton samples. However, residues was detected in pakchoi (0.007-0.013 mg/kg) in Beijing and soil (0.008-0.014 mg/kg) in Changsha in 2008...
  2. Cirou A, Raffoux A, Diallo S, Latour X, Dessaux Y, Faure D. Gamma-caprolactone stimulates growth of quorum-quenching Rhodococcus populations in a large-scale hydroponic system for culturing Solanum tuberosum. Res Microbiol. 2011;162:945-50 pubmed publisher
    ..Most of the assayed Rhodococcus isolates exhibited efficient biocontrol activity for protecting potato tubers. Analytical chemistry approach revealed the rapid degradation of GCL introduced in the plant cultures...
  3. Hakkarainen M, Höglund A, Odelius K, Albertsson A. Tuning the release rate of acidic degradation products through macromolecular design of caprolactone-based copolymers. J Am Chem Soc. 2007;129:6308-12 pubmed
    ..e., different distribution of the weak linkages in the copolymers...
  4. Asrar J, Valentin H, Berger P, Tran M, Padgette S, Garbow J. Biosynthesis and properties of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) polymers. Biomacromolecules. 2002;3:1006-12 pubmed
    ..However, poly(3HB-co-3HHx) exhibited increased activation energy to thermal degradation with increasing 3HHx content...
  5. Zhao K, Deng Y, Chun Chen J, Chen G. Polyhydroxyalkanoate (PHA) scaffolds with good mechanical properties and biocompatibility. Biomaterials. 2003;24:1041-5 pubmed
    ..67. This suggested that the chondrocyte cells grown on PHBHHx/PHB scaffolds presented effective physiological function for generation of cartilage...
  6. Hibino N, Shin oka T, Matsumura G, Ikada Y, Kurosawa H. The tissue-engineered vascular graft using bone marrow without culture. J Thorac Cardiovasc Surg. 2005;129:1064-70 pubmed
    ..To overcome these drawbacks, we have developed a new method for creating a tissue-engineered vascular graft by using bone marrow cells, which can be obtained easily and used immediately, without cell culture...
  7. Chen G, Wu Q. The application of polyhydroxyalkanoates as tissue engineering materials. Biomaterials. 2005;26:6565-78 pubmed
    ..This paper reviews what have been achieved in the PHA tissue engineering area and concluded that the PHA prospective will look very bright in the near future...
  8. Qu X, Wu Q, Liang J, Qu X, Wang S, Chen G. Enhanced vascular-related cellular affinity on surface modified copolyesters of 3-hydroxybutyrate and 3-hydroxyhexanoate (PHBHHx). Biomaterials. 2005;26:6991-7001 pubmed
    ..The above evidences revealed that PFn-PHBHHx would benefit endotheliazation rather than SMCs proliferation. We therefore believed that PFn-PHBHHx would be a promising material as a luminal surface of vascular grafts...
  9. Kawamori T, Uchiya N, Nakatsugi S, Watanabe K, Ohuchida S, Yamamoto H, et al. Chemopreventive effects of ONO-8711, a selective prostaglandin E receptor EP(1) antagonist, on breast cancer development. Carcinogenesis. 2001;22:2001-4 pubmed
    ..These results suggest that EP(1) receptor is associated with breast cancer development and selective PGE receptor EP(1) antagonists may possess chemopreventive effects through the induction of apoptosis without any side effects...

More Information

Publications61

  1. Darracq G, Couvert A, Couriol C, Amrane A, Le Cloirec P. Absorption and biodegradation of hydrophobic volatile organic compounds: determination of Henry's constants and biodegradation levels. Water Sci Technol. 2009;59:1315-22 pubmed publisher
    ..For all the VOC experiments, some components, characteristics of the DEHA degradation, including 2-ethylhexanal, 2-ethylhexanol, 2-ethylhexanoic acid and adipic acid, were identified...
  2. Brozek J, Sasek V, Prokopova I, Chromcová D, Nahlik J, Erbanová P. Degradation of polyesteramides during composting under standard and isothermal conditions. Folia Microbiol (Praha). 2009;54:451-6 pubmed publisher
    ..Ester bonds in polyestramide chains were preferentially cleaved; therefore, the scope of degradation increased with the content of ester units in the copolymer...
  3. Xiang L, Naik J, Hester R. Functional vasodilation in the rat spinotrapezius muscle: role of nitric oxide, prostanoids and epoxyeicosatrienoic acids. Clin Exp Pharmacol Physiol. 2008;35:617-24 pubmed publisher
    ..The results also suggest possible interactions between the synthesis of nitric oxide and prostaglandin or epoxyeicosatrienoic acids during muscle contraction...
  4. Alva Murillo N, Ochoa Zarzosa A, López Meza J. Short chain fatty acids (propionic and hexanoic) decrease Staphylococcus aureus internalization into bovine mammary epithelial cells and modulate antimicrobial peptide expression. Vet Microbiol. 2012;155:324-31 pubmed publisher
    ..In conclusion, NaP and NaH decrease S. aureus internalization into bMEC and modulate TAP gene expression, which may be related to the reduction in bacterial internalization...
  5. Babasola O, Amsden B. Surface eroding, liquid injectable polymers based on 5-ethylene ketal ?-caprolactone. Biomacromolecules. 2011;12:3423-31 pubmed publisher
    ..Cytotoxicity of the hydrolyzed EKC monomer to 3T3 fibroblast cells was comparable to that of ?-caprolactone, suggesting that polymers prepared from EKC may be well tolerated upon in vivo implantation...
  6. Choi J, Kwak S. Hyperbranched poly(epsilon-caprolactone) as a nonmigrating alternative plasticizer for phthalates in flexible PVC. Environ Sci Technol. 2007;41:3763-8 pubmed
    ..7-78% of additives in PVC/DEHP was migrated out of samples, indicating that the HPCL can be used as an alternative plasticizer to remove the potential health risk from migrating phthalates during end use...
  7. Matsumoto G, Hoshino J, Kinoshita Y, Sugita Y, Kubo K, Maeda H, et al. Alveolar bone regeneration using poly-(lactic acid-co-glycolic acid-co-?-caprolactone) porous membrane with collagen sponge containing basic fibroblast growth factor: an experimental study in the dog. J Biomater Appl. 2012;27:485-93 pubmed publisher
    ..These results suggest that the macroporous bioresorbable PLGC membrane plus collagen sponge containing bFGF effectively facilitates healing in GBR procedures...
  8. di Foggia M, Corda U, Plescia E, Taddei P, Torreggiani A. Effects of sterilisation by high-energy radiation on biomedical poly-(epsilon-caprolactone)/hydroxyapatite composites. J Mater Sci Mater Med. 2010;21:1789-97 pubmed publisher
    ..Moreover, the radiation sensitivity of the composites proved almost the same under the two different atmospheres...
  9. Rodrigues A, Mosquera Corral A, Machado A, Moura I, Matos M, Brito A, et al. Use of biopolymers as solid substrates for denitrification. Water Sci Technol. 2012;65:105-11 pubmed publisher
    ..d), and PCL, 97 mg N(2)-N/(g VSS.d), followed by PLA, 53 mg N(2)-N/(g VSS.d). A considerable advantage of using biopolymers in water denitrification is the reduced risk of contaminating the water with soluble biodegradable organic carbon...
  10. Ekaputra A, Zhou Y, Cool S, Hutmacher D. Composite electrospun scaffolds for engineering tubular bone grafts. Tissue Eng Part A. 2009;15:3779-88 pubmed publisher
    ..We conclude that electrospun PCL/Col mesh is a promising material for bone engineering applications. Its combination with osteogenic cell sheets offers a novel and promising strategy for engineering of tubular bone analogs...
  11. Butkus M, Hughes K, Bowman D, Liotta J, Jenkins M, Labare M. Inactivation of Ascaris suum by short-chain fatty acids. Appl Environ Microbiol. 2011;77:363-6 pubmed publisher
    ..Predictions from an inhibition model (50% inhibitory concentration [IC(50)]) based on quantitative structure-activity relationships were congruent with inactivation data...
  12. Chengelis C, Kirkpatrick J, Radovsky A, Shinohara M. A 90-day repeated dose oral (gavage) toxicity study of perfluorohexanoic acid (PFHxA) in rats (with functional observational battery and motor activity determinations). Reprod Toxicol. 2009;27:342-51 pubmed publisher
    ..Based on liver histopathology and liver weight changes, the no-observed-adverse-effect level (NOAEL) for oral administration was 50mg/kg/day for males and 200mg/kg/day for females...
  13. Wang H, Wu X, Zhou T, Deng X, Wang D. [Chemical constituents from the fruits of Kadsura marmorata]. Zhong Yao Cai. 2012;35:396-9 pubmed
    ..To study the chemical constituents from the fruits of Kadsura marmorata...
  14. Xue X, Li D, Yu J, Ma G, Su Z, Hu T. Phenyl linker-induced dense PEG conformation improves the efficacy of C-terminally monoPEGylated staphylokinase. Biomacromolecules. 2013;14:331-41 pubmed publisher
    ..As compared with loose PEG conformation, dense PEG conformation is more efficient to maintain the bioactivity, increase the plasma half-life, and decrease the proteolytic sensitivity and immunogenicity of the PEGylated SAK...
  15. Socaci S, Socaciu C, Tofană M, Raţi I, Pintea A. In-tube extraction and GC-MS analysis of volatile components from wild and cultivated sea buckthorn (Hippophae rhamnoides L. ssp. Carpatica) berry varieties and juice. Phytochem Anal. 2013;24:319-28 pubmed publisher
    ..The volatile compounds are good biomarkers of berry freshness, quality and authenticity...
  16. Agler M, Spirito C, Usack J, Werner J, Angenent L. Development of a highly specific and productive process for n-caproic acid production: applying lessons from methanogenic microbiomes. Water Sci Technol. 2014;69:62-8 pubmed publisher
    ..As a result, n-caproic acid production rates increased to levels comparable to anaerobic digestion systems for solid waste treatment. ..
  17. Zant E, Bosman M, Grijpma D. Combinatorial synthesis of photo-crosslinked biodegradable networks. J Appl Biomater Funct Mater. 2012;10:197-202 pubmed publisher
    ..Photo-crosslinking is a technique that can accelerate the development of novel polymeric biomaterials...
  18. Kuzdrowska M, Annunziata L, Marks S, Schmid M, Jaffredo C, Roesky P, et al. Organometallic calcium and strontium borohydrides as initiators for the polymerization of ?-caprolactone and L-lactide: combined experimental and computational investigations. Dalton Trans. 2013;42:9352-60 pubmed publisher
    ..Gibbs free energy profiles were determined for the three calcium complexes highlighting slightly more active calcium complexes as compared to strontium analogues, in agreement with experimental findings...
  19. Liang L, Lin S, Chien C, Chen M. Zirconium and hafnium complexes containing N-alkyl substituted amine biphenolate ligands: coordination chemistry and living ring-opening polymerization catalysis. Dalton Trans. 2013;42:9286-93 pubmed publisher
    ..Among them, the N-isopropyl derived complexes are most reactive. Polymerizations catalyzed by 2b, 3b and 3c·MeCN were proved to be living. The X-ray structures of 2a·HOiPr, 2a·MeCN, 2c·HOiPr, 2c·MeCN, and 3c·MeCN are presented...
  20. Wang X, Zhang J, Cheng R, Meng F, Deng C, Zhong Z. Facile Synthesis of Reductively Degradable Biopolymers Using Cystamine Diisocyanate as a Coupling Agent. Biomacromolecules. 2016;17:882-90 pubmed publisher
    ..Hence, cystamine diisocyanate appears to be an innovative coupling agent that facilitates versatile synthesis of biocompatible and reductively degradable biopolymers. ..
  21. Drobnik J, Krucinska I, Komisarczyk A, Sporny S, Szczepanowska A, Ciosek J. Effects of electrospun scaffolds of di-O-butyrylchitin and poly-(?-caprolactone) on wound healing. Can J Surg. 2017;60:162-171 pubmed
    ..We sought to determine the usefulness of electrospun dibutyrylchitin (DBC) or poly-(?-caprolactone [PCL]), in wound treatment. We investigated the mechanisms of action of these polymers on wound healing...
  22. Zeng C, Tanaka S, Suzuki Y, Fujii S. Impact of feed water pH and membrane material on nanofiltration of perfluorohexanoic acid in aqueous solution. Chemosphere. 2017;183:599-604 pubmed publisher
    ..The mechanisms behind these phenomena were also discussed. The results obtained in this study should be very useful for the process design in practical engineering. ..
  23. Burger S, Yang W. Sequential quadratic programming method for determining the minimum energy path. J Chem Phys. 2007;127:164107 pubmed
  24. Cavani F, Raabova K, Bigi F, Quarantelli C. A rationale of the Baeyer-Villiger oxidation of cyclohexanone to ?-caprolactone with hydrogen peroxide: unprecedented evidence for a radical mechanism controlling reactivity. Chemistry. 2010;16:12962-9 pubmed publisher
    ..The proper choice of the solvent, which also may act as a radical scavenger, both without catalyst and with TS-1, is a powerful tool for controlling the rates of the various reactions involved...
  25. Kim J, Kyung D, Yun H, Cho B, Seo J, Cha M, et al. Cloning and characterization of a novel beta-transaminase from Mesorhizobium sp. strain LUK: a new biocatalyst for the synthesis of enantiomerically pure beta-amino acids. Appl Environ Microbiol. 2007;73:1772-82 pubmed
    ..3S)-Amino-3-phenylpropionic acid was produced from the ketocarboxylic acid ester substrate by coupled reaction with a lipase using 3-aminobutyric acid as amino donor...
  26. Zhou Y, Wang J, Li X, Fu X, Yan Z, Zeng Y, et al. Studies on the chemical constituents of Ilex pubescens. J Asian Nat Prod Res. 2008;10:827-31 pubmed publisher
    ..Three new compounds, ilexisochromane (1), ilex acid A (2), and ilex acid B (3), were isolated from the roots of Ilex pubescens. Their structures were elucidated using the combination of 1- and 2-D NMR and mass spectrometry analyses...
  27. Brychtova K, Opatrilova R, Raich I, Kalinowski D, Dvorakova L, Placek L, et al. Investigating the activity of 2-substituted alkyl-6-(2,5-dioxopyrrolidin-1-yl)hexanoates as skin penetration enhancers. Bioorg Med Chem. 2010;18:8556-65 pubmed publisher
    ..The relationships between the lipophilicity and the chemical structure of the studied compounds, as well as the correlation between their chemical structure and transdermal penetration-enhancing activity, are discussed...
  28. Tripathi L, Wu L, Chen J, Chen G. Synthesis of Diblock copolymer poly-3-hydroxybutyrate -block-poly-3-hydroxyhexanoate [PHB-b-PHHx] by a ?-oxidation weakened Pseudomonas putida KT2442. Microb Cell Fact. 2012;11:44 pubmed publisher
  29. Duan J, Huo X, Du W, Liang J, Wang D, Yang S. Biodegradation of kraft lignin by a newly isolated anaerobic bacterial strain, Acetoanaerobium sp. WJDL-Y2. Lett Appl Microbiol. 2016;62:55-62 pubmed publisher
    ..WJDL-Y2 (accession no. KF176997),was isolated from the sludge of a pulp and paper mill. Strain Y2 can play an important role in treating pulp and paper wastewater, as well as breaking down materials for biofuel and chemical production. ..
  30. Liu P, Chernyshov A, Najdi T, Fu Y, Dickerson J, Sandmeyer S, et al. Membrane stress caused by octanoic acid in Saccharomyces cerevisiae. Appl Microbiol Biotechnol. 2013;97:3239-51 pubmed publisher
    ..Thus, we have provided quantitative evidence that carboxylic acids damage the yeast membrane and that manipulation of the lipid content of the membrane can increase tolerance, and possibly production, of these valuable products...
  31. Vavrova K, Lorencová K, Novotný J, Holy A, Hrabálek A. Permeation enhancer dodecyl 6-(dimethylamino)hexanoate increases transdermal and topical delivery of adefovir: influence of pH, ion-pairing and skin species. Eur J Pharm Biopharm. 2008;70:901-7 pubmed publisher
    ..These results offer an attractive alternative to established routes of administration of adefovir and other acyclic nucleoside phosphonates...
  32. Takahashi M, Inoue S, Hayama K, Ninomiya K, Abe S. [Inhibition of Candida mycelia growth by a medium chain fatty acids, capric acid in vitro and its therapeutic efficacy in murine oral candidiasis]. Med Mycol J. 2012;53:255-61 pubmed
    ..These results suggest that all four fatty acids, and especially capric acid, have potential as substances supporting anti-Candida treatment...
  33. Widjaja L, Kong J, Chattopadhyay S, Lipik V, Liow S, Abadie M, et al. Triblock copolymers of ?-caprolactone, trimethylene carbonate, and L-lactide: effects of using random copolymer as hard-block. J Mech Behav Biomed Mater. 2012;6:80-8 pubmed publisher
    ..We expect to use these polymers in a variety of applications, including stent coatings, fully-degradable stents and atrial septal defect occluders...
  34. Akpa M, Point F, Sawadogo S, Radenne A, Mounier C. Inhibition of insulin and T3-induced fatty acid synthase by hexanoate. Lipids. 2010;45:997-1009 pubmed publisher
    ..This effect is partially transcriptional, targeting the TRE on the FAS promoter. ..
  35. Nebolsin V, Zhdanov V, Zyuzkov G, Udut E, Khrichkova T, Simanina E, et al. Mechanisms of protective effect of Dicarbamin on the blood system in cytostatic treatment. Bull Exp Biol Med. 2011;150:343-7 pubmed
  36. Loveless S, Slezak B, Serex T, Lewis J, Mukerji P, O Connor J, et al. Toxicological evaluation of sodium perfluorohexanoate. Toxicology. 2009;264:32-44 pubmed publisher
    ..Benchmark doses (BMDL10) for nasal lesions were 13 and 21 mg/(kg day) for male and female rats, respectively. The relevance of the nasal lesions to humans is not known...
  37. Gerber A, Masuno K, Diamond M. Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening. Proc Natl Acad Sci U S A. 2009;106:4929-34 pubmed publisher
    ..Our results have important implications for the development of GR modulators and the identification of cross-talk pathways that control selective GR gene regulation...
  38. Zhang K, Wang H, Huang C, Su Y, Mo X, Ikada Y. Fabrication of silk fibroin blended P(LLA-CL) nanofibrous scaffolds for tissue engineering. J Biomed Mater Res A. 2010;93:984-93 pubmed publisher
    ..These results suggested that SF/P(LLA-CL) blended nanofibrous scaffolds might be potential candidates for vascular tissue engineering...
  39. Machado H, Correia R, Covas J. Synthesis, extrusion and rheological behaviour of PU/HA composites for biomedical applications. J Mater Sci Mater Med. 2010;21:2057-66 pubmed publisher
    ..Polymer chemistry seems to be affected by ageing but not so by the presence of filler. Ageing is characterized by a decrease in the concentration of hydrogen bonds involving between urethane linkages...
  40. Adnani A, Basri M, Chaibakhsh N, Ahangar H, Salleh A, Rahman R, et al. Chemometric analysis of lipase-catalyzed synthesis of xylitol esters in a solvent-free system. Carbohydr Res. 2011;346:472-9 pubmed publisher
    ..5%) shows that the model derived from the Taguchi orthogonal array can be used for optimization and better understanding of the effect of reaction parameters on the enzymatic synthesis of xylitol esters in a solvent-free system...
  41. Hermans I, Jacobs P, Peeters J. The formation of byproducts in the autoxidation of cyclohexane. Chemistry. 2007;13:754-61 pubmed
    ..The pathway by which these radicals are converted into the observed and quantified byproducts is derived in this work. In this liquid-phase reaction, solvent cages were found very important, steering the fate of nascent species...
  42. Lomas A, Webb W, Han J, Chen G, Sun X, Zhang Z, et al. Poly (3-hydroxybutyrate-co-3-hydroxyhexanoate)/collagen hybrid scaffolds for tissue engineering applications. Tissue Eng Part C Methods. 2013;19:577-85 pubmed publisher
    ..PHBHHx/collagen scaffolds have been successfully used to culture hMSC and SDhESC over an extended period supporting the potential of this scaffold combination in future tissue engineering applications. ..
  43. Svechnikova I, Svechnikov K, Soder O. The influence of di-(2-ethylhexyl) phthalate on steroidogenesis by the ovarian granulosa cells of immature female rats. J Endocrinol. 2007;194:603-9 pubmed
    ..Together, these data indicate that DEHP exerts dual effects on the pituitary-gonadal axis, stimulating the hormonal function of the pituitary and, at the same time, by inhibiting steroidogenesis by GCs...
  44. Gao J, Ramsay J, Ramsay B. Fed-batch production of poly-3-hydroxydecanoate from decanoic acid. J Biotechnol. 2016;218:102-7 pubmed publisher
    ..16 g L(-1)h(-1) with the production of each gram of PHA requiring only 1.16 g of decanoic acid. The final PHA composition (on a molar basis) was 78% 3-hydroxydecanoate, 11% 3-hydroxyoctanoate and 11% 3-hydroxyhexanoate. ..
  45. Sheng N, Li J, Liu H, Zhang A, Dai J. Interaction of perfluoroalkyl acids with human liver fatty acid-binding protein. Arch Toxicol. 2016;90:217-27 pubmed publisher
    ..Arg122 and Asn111 played a pivotal role in these interactions. Our findings may help understand the distribution pattern, bioaccumulation, elimination, and toxicity of PFAAs in humans. ..
  46. Bassi N, Beck M, Fawcett R. Allergic contact dermatitis from 4-chloro-2-[methylthio]pyrimidine-5-carboxylic acid ethyl ester and methyl 4-hydroxy-2-hexynoate in a laboratory chemist. Contact Dermatitis. 2008;58:115-6 pubmed publisher
    ..We report a case of allergic contact dermatitis to 4-chloro-2-[methylthio]pyrimidine-5-carboxylic acid ethyl ester and methyl 4-hydroxy-2-hexynoate in a laboratory chemist...
  47. Hille A, He M, Ochmann C, Neu T, Horn H. Application of two component biodegradable carriers in a particle-fixed biofilm airlift suspension reactor: development and structure of biofilms. Bioprocess Biosyst Eng. 2009;32:31-9 pubmed publisher
    ..Strong changes of substrate concentration during fed-batch mode operation of the reactor enhance the growth of filamentous biofilms on the carriers. Mass transport in the outer regions of such biofilms was mainly driven by advection...
  48. Tu Q, Wang J, Liu R, Chen Y, Zhang Y, Wang D, et al. Click synthesis of neutral, cationic, and zwitterionic poly(propargyl glycolide)-co-poly(?-caprolactone)-based aliphatic polyesters as antifouling biomaterials. Colloids Surf B Biointerfaces. 2013;108:34-43 pubmed publisher
    ..The newly prepared polyesters could be developed as promising anti-fouling materials with extensive biomedical applications...
  49. Novotný J, Kovarikova P, Novotný M, Janůšová B, Hrabálek A, Vavrova K. Dimethylamino acid esters as biodegradable and reversible transdermal permeation enhancers: effects of linking chain length, chirality and polyfluorination. Pharm Res. 2009;26:811-21 pubmed publisher
    ..Effects of chirality, linking chain length and polyfluorination were investigated...
  50. Sánchez Otero M, Quintana Castro R, Mora González P, Márquez Molina O, Valerio Alfaro G, Oliart Ros R. Enzymatic reactions and synthesis of n-butyl caproate: esterification, transesterification and aminolysis using a recombinant lipase from Geobacillus thermoleovorans CCR11. Environ Technol. 2010;31:1101-6 pubmed publisher
  51. Lu X, Li M, Zhu X, Fan F, Wang L, Ma J. Microbial synthesized biodegradable PHBHHxPEG hybrid copolymer as an efficient intracellular delivery nanocarrier for kinase inhibitor. BMC Biotechnol. 2014;14:4 pubmed publisher
    ..In this study, the novel PHBHHxPEG NPs were prepared and investigated to serve as intracellular delivery nanocarriers for sustained release of hydrophobic kinase inhibitors...
  52. Xue Y, Dånmark S, Xing Z, Arvidson K, Albertsson A, Hellem S, et al. Growth and differentiation of bone marrow stromal cells on biodegradable polymer scaffolds: an in vitro study. J Biomed Mater Res A. 2010;95:1244-51 pubmed publisher
    ..The promising results of this in vitro study indicate that these copolymers warrant further evaluation for potential application in bone tissue engineering...