p aminoazobenzene

Summary

Summary: Used in the form of its salts as a dye and as an intermediate in manufacture of Acid Yellow, diazo dyes, and indulines.

Top Publications

  1. Kopinke D, Sasine J, Swift J, Stephens W, Piotrowski T. Retinoic acid is required for endodermal pouch morphogenesis and not for pharyngeal endoderm specification. Dev Dyn. 2006;235:2695-709 pubmed
    ..These results demonstrate that the developmental processes underlying pharyngeal arch defects differ depending on when RA signaling is disturbed during development...
  2. Maves L, Kimmel C. Dynamic and sequential patterning of the zebrafish posterior hindbrain by retinoic acid. Dev Biol. 2005;285:593-605 pubmed
    ..Our results support a new model of dynamic RA action in the hindbrain, in which a temporally increasing source of RA is required to sequentially initiate progressively more posterior rhombomere identities...
  3. Begemann G, Marx M, Mebus K, Meyer A, Bastmeyer M. Beyond the neckless phenotype: influence of reduced retinoic acid signaling on motor neuron development in the zebrafish hindbrain. Dev Biol. 2004;271:119-29 pubmed
    ..In addition, blockage of RA-mediated signaling not only interferes with the differentiation of branchiomotor neurons and their axons in the hindbrain, but also affects the development of the posterior lateral line nerve...
  4. Yi Y, Farrow M, Korblova E, Walba D, Furtak T. High-sensitivity aminoazobenzene chemisorbed monolayers for photoalignment of liquid crystals. Langmuir. 2009;25:997-1003 pubmed publisher
  5. Laguna Argente C, Roche E, Vilata J, De La Cuadra J. [Unilateral contact dermatitis caused by footwear]. Actas Dermosifiliogr. 2007;98:718-9 pubmed
  6. Degawa M, Namiki M, Yoshimoto N, Makino M, Iwamoto M, Nemoto K, et al. Constitutive expression of cytochrome p450 genes in newly established rat hepatic cell lines. J Biochem. 2003;133:825-31 pubmed
  7. Uter W, Lessmann H, Geier J, Becker D, Fuchs T, Richter G. The spectrum of allergic (cross-)sensitivity in clinical patch testing with 'para amino' compounds. Allergy. 2002;57:319-22 pubmed
    ..Further research should aim at (i) establishing the mechanism of cross-reactivity to 'para amino' compounds and (ii) identifying exposures in the environment. ..
  8. Purkait M, DasGupta S, De S. Performance of TX-100 and TX-114 for the separation of chrysoidine dye using cloud point extraction. J Hazard Mater. 2006;137:827-35 pubmed
    ..A method is presented to calculate the feed surfactant concentration required for the removal of dyes up to a level of 3.82x10(-6) M. The developed correlations may be useful to design a cloud point extractor of a desired efficiency. ..
  9. Mittal A, Mittal J, Malviya A, Gupta V. Removal and recovery of Chrysoidine Y from aqueous solutions by waste materials. J Colloid Interface Sci. 2010;344:497-507 pubmed publisher
    ..Column experiments indicate practical utility of the adsorbents for eradicating hazardous dyes from effluents. The recovery of the adsorbed dye from bottom ash and de-oiled soya, have been found to be 85% and 99%, respectively. ..

More Information

Publications82

  1. Degawa M, Yamada H, Hishinuma T, Masuko T, Hashimoto Y. Organ selective induction of cytochrome P-448 isozymes in the rat by 2-methoxy-4-aminoazobenzene and 3-methylcholanthrene. J Biochem. 1987;101:1437-45 pubmed
  2. Łukasik N, Wagner Wysiecka E. Anion binding by p-aminoazobenzene-derived aromatic amides: spectroscopic and electrochemical studies. Photochem Photobiol Sci. 2017;16:1570-1579 pubmed publisher
    ..The E ⇄ Z isomerization process of tripodal amide 4 in chloroform was studied. The effect of anions on Z to E thermal back isomerization was investigated. ..
  3. Bentley R. Different roads to discovery; Prontosil (hence sulfa drugs) and penicillin (hence beta-lactams). J Ind Microbiol Biotechnol. 2009;36:775-86 pubmed publisher
    ..The very different pathways leading to their development and to that of the successor antibacterials (sulfa drugs, further penicillins, semi-synthetic penicillins), including the role played by patents, are discussed. ..
  4. Xie Z, Hayakawa R, Sugiura M, Kojima H, Konishi H, Ichihara G, et al. Experimental study on skin sensitization potencies and cross-reactivities of hair-dye-related chemicals in guinea pigs. Contact Dermatitis. 2000;42:270-5 pubmed
    ..Their cross-reactivities are different in sensitized conditions, respectively. The cross-reactivities to PPD were higher than those to PTD, PAP and PAB. ..
  5. Ingle C, Drinkwater N. Mutational specificities of 1'-acetoxysafrole, N-benzoyloxy-N-methyl-4-aminoazobenzene, and ethyl methanesulfonate in human cells. Mutat Res. 1989;220:133-42 pubmed
    ..The broad spectrum of base substitution mutations observed for AcOS and BzOMAB may indicate the frequent insertion of a variety of bases during replicative bypass of aralkylated bases in human cells. ..
  6. Zhang Y, Zhou B, Liu Y, Zhou C, Ding X, Liu Y. Fluorescence study on the interaction of bovine serum albumin with p-aminoazobenzene. J Fluoresc. 2008;18:109-18 pubmed
    ..57 to 51.83%) in the presence of PAAB. These revealed that the microenvironment and conformation of BSA were changed in the binding reaction. ..
  7. Dando P, Barrett A. Quantification of peptide aldehyde ligands immobilized for the affinity chromatography of endopeptidases. Anal Biochem. 1992;204:328-31 pubmed
    ..Analyses by the new method show that four matrices offered commercially for this type of immobilization differ greatly in coupling capacity and stability of the conjugate under conditions of affinity chromatography. ..
  8. Manam S, Storer R, Prahalada S, Leander K, Kraynak A, Ledwith B, et al. Activation of the Ha-, Ki-, and N-ras genes in chemically induced liver tumors from CD-1 mice. Cancer Res. 1992;52:3347-52 pubmed
  9. Sharma S, Shariatmadar S, Krishan A. Electronic volume, aldehyde dehydrogenase, and stem cell marker expression in cells from human peripheral blood apheresis samples. Cytometry B Clin Cytom. 2010;78:123-9 pubmed publisher
    ..The CD90 cells in both the ALDH1(bright) and ALDH1(dim) populations had the smallest mean electronic volume when compared with similar cells with CD117 expression. ..
  10. Colin Chamley N, Cambie M, Barhoum K, Kalis B. [Lichenoid contact dermatitis from the ink of a red pen]. Ann Dermatol Venereol. 1998;125:21-2 pubmed
    ..This contact mechanism would nevertheless explain both localizations of lichen reaction in our patient. ..
  11. Chidambaram N, Burgess D. A novel in vitro release method for submicron sized dispersed systems. AAPS PharmSci. 1999;1:E11 pubmed
    ..Sink conditions were violated using the side-by-side diffusion cell method but were maintained in the dialysis bag method since emulsions were diluted infinitely in the donor phase. ..
  12. King L, Schwartz N, Domowicz M. Glial migratory streams in the developing hindbrain: a slice culture approach. J Neurosci Methods. 2009;177:30-43 pubmed publisher
    ..This slice culture system is thus an innovative and robust tool for examining glial cell migration and the extracellular molecular and signaling pathways which regulate glial differentiation. ..
  13. Manam S, Storer R, Prahalada S, Leander K, Kraynak A, Hammermeister C, et al. Activation of the Ki-ras gene in spontaneous and chemically induced lung tumors in CD-1 mice. Mol Carcinog. 1992;6:68-75 pubmed
  14. Degawa M, Agatsuma T, Hashimoto Y. Species difference among experimental rodents in the activity and induction of cytochrome P-450 isozymes for mutagenic activation of carcinogenic aromatic amines. Jpn J Cancer Res. 1990;81:1253-8 pubmed
    ..By means of these assays, we examined the species differences among rodents in the activity and induction rate of hepatic cytochrome P-450 isozymes responsible for the mutagenic activation of carcinogenic aromatic amines. ..
  15. Muramoto G, Russell J, Safi R, Salter A, Himburg H, Daher P, et al. Inhibition of aldehyde dehydrogenase expands hematopoietic stem cells with radioprotective capacity. Stem Cells. 2010;28:523-34 pubmed publisher
    ..Pharmacologic inhibition of ALDH has therapeutic potential as a means to amplify ST-HSCs for transplantation purposes...
  16. Sandhu P, Chipman J. Bacterial mutagenesis and hepatocyte unscheduled DNA synthesis induced by chrysoidine azo-dye components. Mutat Res. 1990;240:227-36 pubmed
    ..92 and 23.5 net nuclear grains at a dose level of 2.5 micrograms/incubation. Since each dye was equi-potent, methyl substitution had little influence on genetic toxicity in hepatocytes...
  17. Iyer H. History revisited-Prontosil red. J Emerg Med. 2008;35:209-10 pubmed publisher
  18. Karmakar R, Banik S, Chatterjee M. Inhibitory effect of vitamin D3 on 3'methyl-4-dimethyl-amino-azobenzene-induced rat hepatocarcinogenesis: a study on antioxidant defense enzymes. J Exp Ther Oncol. 2002;2:193-9 pubmed
    ..VD3 was proved to be an effective antitumor drug during the initiation/promotion phases of hepatic carcinogenesis but the effect was found to be less prominent during initiation and promotion phases...
  19. Johns C, Macka M, Haddad P. Highly sensitive indirect photometric detection of cations by capillary electrophoresis with the cationic dye chrysoidine. J Chromatogr A. 2003;997:87-94 pubmed
  20. Cao X, Chen Y, Zhou H, Fang D. [Color reaction of chromogenic reagent O-hydroxybenzenediazoaminoazobenzene with thallium (III) and its application]. Guang Pu Xue Yu Guang Pu Fen Xi. 2001;21:350-2 pubmed
    ..L-1 Tl(III). The method has been applied to the direct determination of trace amounts of thallium in waste water and in geological samples by using polyurethane foam to absorb and separate Tl(III) with satisfactory results...
  21. Yamazaki H, Degawa M, Funae Y, Imaoka S, Inui Y, Guengerich F, et al. Roles of different cytochrome P450 enzymes in bioactivation of the potent hepatocarcinogen 3-methoxy-4-aminoazobenzene by rat and human liver microsomes. Carcinogenesis. 1991;12:133-9 pubmed
    ..From these results it is concluded that multiple P450 enzymes in rat and human liver microsomes are involved in the bioactivation of 3-MeO-AAB, regardless of its selective induction of the rat P450IA2 gene...
  22. Kojima M, Degawa M, Hashimoto Y, Tada M. 32P-postlabeling analysis of DNA adducts in rat livers after treatment with genotoxic and non-genotoxic 4-aminoazobenzene derivatives. Cancer Lett. 1991;58:199-204 pubmed
  23. Sarrazin A, Nuñez V, Sapede D, Tassin V, Dambly Chaudiere C, Ghysen A. Origin and early development of the posterior lateral line system of zebrafish. J Neurosci. 2010;30:8234-44 pubmed publisher
    ..The delayed formation of secondary afferent neurons accounts for the capability of the fish to form a new PLL ganglion after ablation of the embryonic ganglion at 24 hpf...
  24. Kojima M, Degawa M, Hashimoto Y, Tada M. Different effects of DNA adducts induced by carcinogenic and noncarcinogenic azo dyes on in vitro DNA synthesis. Biochem Biophys Res Commun. 1991;179:817-23 pubmed
    ..Thus different effects on DNA replication between 3-MeO-AAB- and 2-MeO-AAB-adducts might be a reflection of differences in their carcinogenic potency...
  25. Skazik C, Grannemann S, Wilbers L, Merk H, Coenraads P, Breuer S, et al. Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances. Contact Dermatitis. 2008;59:203-11 pubmed publisher
    ..Patch tests to p-phenylenediamine (PPD) and related substances often show concurrent reactions that can be attributed to separate sensitization or cross-reactivity...
  26. Manam S, Shinder G, Joslyn D, Kraynak A, Hammermeister C, Leander K, et al. Dose-related changes in the profile of ras mutations in chemically induced CD-1 mouse liver tumors. Carcinogenesis. 1995;16:1113-9 pubmed
    ..Our results demonstrate that the dosing procedure can materially affect the pattern of ras gene mutation in mouse liver tumors...
  27. Degawa M, Miura S, Yoshinari K, Hashimoto Y. Altered expression of hepatic CYP1A enzymes in rat hepatocarcinogenesis. Jpn J Cancer Res. 1995;86:535-9 pubmed
    ..The present findings indicated that individual CYP1A enzymes are differently regulated, and the expression of CYP1A2 is reduced preferentially in the liver bearing hyperplastic nodules...
  28. Dunn P. Dr Leonard Colebrook, FRS (1883-1967) and the chemotherapeutic conquest of puerperal infection. Arch Dis Child Fetal Neonatal Ed. 2008;93:F246-8 pubmed publisher
  29. Papadokostaki K, Petropoulos J. Kinetics of release of a model disperse dye from supersaturated cellulose acetate matrices. J Control Release. 1998;54:251-64 pubmed
  30. Hishinuma T, Degawa M, Masuko T, Hashimoto Y. Induction of cytochrome P-448 isozyme(s) in primary cultured rat hepatocytes by drugs which induce different isozymes in vivo. Biochem Biophys Res Commun. 1987;148:947-53 pubmed
    ..These results suggest that the responses of rat hepatocytes to cytochrome P-450 inducers are different in in vivo and in vitro...
  31. Eazhilarasi G, Nagalakshmi R, Krishnakumar V. Studies on crystal growth, vibrational and optical properties of organic nonlinear optical crystal: p-aminoazobenzene. Spectrochim Acta A Mol Biomol Spectrosc. 2008;71:502-7 pubmed publisher
    ..Optical absorption studies show the effective transmission in the entire UV-vis region. The second harmonic generation results show the suitability of this material for NLO applications...
  32. Devos S, van der Valk P. The risk of active sensitization to PPD. Contact Dermatitis. 2001;44:273-5 pubmed
    ..g., head or feet) prompts the testing of PPD. Testing PPD combined with para-aminoazobenzene does lead to a slight increase in positive reactions to PPD (p<0.25) and to an increase in irrelevant reactions (p<0.10)...
  33. Wang G, Shang D, Guo Y, Wei J, Li L, Hu L. [Synthesis of azobenzol compound and analytical application in a new catalytic spectrophotometry system]. Guang Pu Xue Yu Guang Pu Fen Xi. 2003;23:619-20 pubmed
    ..The detection limit was 0.048 microgram.L-1 for copper (II). The method has been used for determining trace copper(II) in human hair and aluminum alloy samples with satisfactory results...
  34. Seidenari S, Giusti F, Massone F, Mantovani L. Sensitization to disperse dyes in a patch test population over a five-year period. Am J Contact Dermat. 2002;13:101-7 pubmed
    ..In spite of sporadic data pointing at the role of textile dyes as important contact allergens, only few studies have addressed the issue of the frequency of sensitization to textile dyes in populations of consecutive patients...
  35. Prieto J. [Return to the future 10 years later]. Rev Esp Quimioter. 2007;20:241-4 pubmed
  36. Patnaik S, Kumar P, Garg B, Gandhi R, Gupta K. Photomodulation of PS-modified oligonucleotides containing azobenzene substituent at pre-selected positions in phosphate backbone. Bioorg Med Chem. 2007;15:7840-9 pubmed
  37. Sasaki Y, Izumiyama F, Nishidate E, Matsusaka N, Tsuda S. Detection of rodent liver carcinogen genotoxicity by the alkaline single-cell gel electrophoresis (Comet) assay in multiple mouse organs (liver, lung, spleen, kidney, and bone marrow). Mutat Res. 1997;391:201-14 pubmed
    ..BHC, which is not genotoxic in in vitro tests, did not show any effects. We suggest that it may be possible to use the alkaline SCG assay to detect in vivo activity of chemicals whose genotoxicity is not expressed in bone marrow cells...
  38. Degawa M, Kojima M, Yoshinari K, Tada M, Hashimoto Y. DNA adduct formation of hepatocarcinogenic aromatic amines in rat liver: effect of cytochrome P450 inducers. Cancer Lett. 1994;79:77-81 pubmed
    ..The increase of aromatic amine DNA adducts by pretreatment with a CYP inducer was proportional to the activity of induced CYP isozyme(s) responsible for the mutagenic activation of each aromatic amine...
  39. Esancy J, Freeman H, Claxton L. The effect of alkoxy substituents on the mutagenicity of some aminoazobenzene dyes and their reductive-cleavage products. Mutat Res. 1990;238:1-22 pubmed
    ..The results from the latter aspect of this study suggest that the mutagenicity of aminoazobenzene dyes can not be accounted for solely from the properties of their reductive-cleavage products...
  40. Zissi U, Lyberatos G. Partial degradation of p-aminoazobenzene by a defined mixed culture of Bacillus subtilis and Stenotrophomonas maltophilia. Biotechnol Bioeng. 2001;72:49-54 pubmed
    ..The two bacteria are shown to coexist in a CSTR for some ranges of the operating variables...
  41. de Waard van der Spek F, Oranje A. Allergic contact dermatitis to chlorhexidine and para-amino compounds in a 4-year-old boy: a very rare observation. Contact Dermatitis. 2008;58:239-41 pubmed publisher
  42. Castle L, Damant A, Honeybone C, Johns S, Jickells S, Sharman M, et al. Migration studies from paper and board food packaging materials. Part 2. Survey for residues of dialkylamino benzophenone UV-cure ink photoinitiators. Food Addit Contam. 1997;14:45-52 pubmed
    ..There was no measurable migration of MK at a detection limit of 2 micrograms/kg food. It is concluded, therefore, that the concentrations of MK present in the packaging samples analysed are unlikely to pose a risk to human health...
  43. Ledwith B, Joslyn D, Troilo P, Leander K, Clair J, Soper K, et al. Induction of minisatellite DNA rearrangements by genotoxic carcinogens in mouse liver tumors. Carcinogenesis. 1995;16:1167-72 pubmed
    ..Our results suggest that DNA fingerprinting may be a valuable assay for differentiating certain chemically induced tumors from spontaneous tumors...
  44. von Engelhardt W, Gros G, Burmester M, Hansen K, Becker G, Rechkemmer G. Functional role of bicarbonate in propionate transport across guinea-pig isolated caecum and proximal colon. J Physiol. 1994;477:365-71 pubmed
    ..5. Results support the view that a considerable proportion of short-chain fatty acids (SCFAs) is absorbed via a SCFA(-)-HCO3- exchange...
  45. Ozawa S, Abu Zeid M, Kawakubo Y, Toyama S, Yamazoe Y, Kato R. Monomorphic and polymorphic isozymes of arylamine N-acetyltransferases in hamster liver: purification of the isozymes and genetic basis of N-acetylation polymorphism. Carcinogenesis. 1990;11:2137-44 pubmed
    ..These results indicate that the polymorphic appearance of an acetyltransferase, AT-II, is responsible for the N-acetylation polymorphism in individual hamsters...
  46. Kazakova N, Li H, Mora A, Jessen K, Mirsky R, Richardson W, et al. A screen for mutations in zebrafish that affect myelin gene expression in Schwann cells and oligodendrocytes. Dev Biol. 2006;297:1-13 pubmed
    ..Timed application of the RA synthesis inhibitor DEAB to wild type embryos showed that RA signalling is required at least 48 h before the onset of myelin protein synthesis in both CNS and PNS...
  47. Shokrollahi A, Ghaedi M, Hossaini O, Khanjari N, Soylak M. Cloud point extraction and flame atomic absorption spectrometry combination for copper(II) ion in environmental and biological samples. J Hazard Mater. 2008;160:435-40 pubmed publisher
    ..b/m, n=10) of 0.6ngmL(-1) along with preconcentration factor of 30 and enrichment factor of 41.1 with R.S.D. of 1.0% for Cu was achieved. The proposed procedure was applied to the analysis of various environmental and biological samples...
  48. Kojima M, Morita T, Degawa M, Hashimoto Y, Tada M. Differences in DNA damage induced by mutagenic and nonmutagenic 4-aminoazobenzene derivatives in Escherichia coli. Mutat Res. 1992;274:65-71 pubmed
    ..Moreover, N-OH-3-MeO-AAB, but not N-OH-2-MeO-AAB, could induce recA and umuC gene expression, which was higher in uvrA strains than in the wild type...
  49. Reifenberger M, Arnett K, Gatto C, Milanick M. Extracellular terbium and divalent cation effects on the red blood cell Na pump and chrysoidine effects on the renal Na pump. Blood Cells Mol Dis. 2007;39:7-13 pubmed
    ..Chrysoidine and similar compounds may be useful as optical probes of the E(in) conformation...
  50. Abuaf P, Kadlubar F, Grunberger D. Circular dichroism of poly(dG-dC) modified by the carcinogens N-methyl-4-aminoazobenzene or 4-aminobiphenyl. Nucleic Acids Res. 1987;15:7125-36 pubmed
    ..These data indicate that ABP and MAB can enhance conversion from B to Z conformation in alternating purine-pyrimidine sequences...
  51. Chute J, Muramoto G, Whitesides J, Colvin M, Safi R, Chao N, et al. Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells. Proc Natl Acad Sci U S A. 2006;103:11707-12 pubmed
    ..Modulation of ALDH activity and retinoid signaling is a previously unrecognized and effective strategy to amplify human HSCs...
  52. Degawa M, Namiki M, Miura S, Ueno H, Hashimoto Y. A male-specific renal cytochrome P-450 isozyme(s) responsible for mutagenic activation of 3-methoxy-4-aminoazobenzene in mice. Biochem Biophys Res Commun. 1988;152:843-8 pubmed
    ..All these findings suggest that in mice, there is a male-specific renal 3-MeO-AAB activation enzyme(s), a cytochrome P-450 isozyme(s), which is different, at least in proportion and/or in nature, from hepatic cytochrome P-450 isozymes...
  53. Hanna P, el Ghandour A, McCormack M. Analogues of N-hydroxy-4-acetylaminobiphenyl as substrates and inactivators of hamster hepatic acetyltransferases. Xenobiotica. 1990;20:739-51 pubmed
    ..The inactivation of N,N-AT by N-OH-AAS (7) does not appear to involve electrophiles that are released from the active site and subsequently become covalently bound to the enzyme...
  54. Degawa M, Arai H, Kubota M, Hashimoto Y. Ionic lead, but not other ionic metals (Ni2+, Co2+ and Cd2+), suppresses 2-methoxy-4-aminoazobenzene-mediated cytochrome P450IA2 (CYP1A2) induction in rat liver. Biol Pharm Bull. 1995;18:1215-8 pubmed
    ..The level of CYP1A2 induced with 2-MeO-AAB was decreased along with increase in that of the induced GST-P...
  55. Vazzana I, Sparatore F, Fadda G, Manca C. N-[4-(R',R"-phenylazo)aryl]aminolupinanes with antitubercular activity. Farmaco. 1993;48:737-47 pubmed
    ..I.C. in the range 0.1-1 microgram/ml...
  56. Reijntjes S, Rodaway A, Maden M. The retinoic acid metabolising gene, CYP26B1, patterns the cartilaginous cranial neural crest in zebrafish. Int J Dev Biol. 2007;51:351-60 pubmed
  57. Liedtke D, Winkler C. Midkine-b regulates cell specification at the neural plate border in zebrafish. Dev Dyn. 2008;237:62-74 pubmed
    ..Our results imply that Mdkb is required for the earliest steps of cell specification at the neural plate border in zebrafish...
  58. Southan G, Szabo C, Thiemermann C. Inhibition of the induction of nitric oxide synthase by spermine is modulated by aldehyde dehydrogenase. Biochem Biophys Res Commun. 1994;203:1638-44 pubmed
    ..Thus, inhibition of aldehyde dehydrogenase activity in vitro or in vivo may be a useful approach to enhance the inhibitory effect of polyamines or polyamine aldehydes on iNOS induction...
  59. Ohnishi S, Murata M, Degawa M, Kawanishi S. Oxidative DNA damage induced by an N-hydroxy metabolite of carcinogenic 4-dimethylaminoazobenzene. Jpn J Cancer Res. 2001;92:23-9 pubmed
    ..The main reactive species are probably DNA-copper-hydroperoxo complexes. We conclude that oxidative DNA damage may play an important role in the carcinogenic processes of DAB, in addition to DNA adduct formation...
  60. Mimura M, Baba T, Yamazaki H, Ohmori S, Inui Y, Gonzalez F, et al. Characterization of cytochrome P-450 2B6 in human liver microsomes. Drug Metab Dispos. 1993;21:1048-56 pubmed
    ..abstract truncated at 250 words)..
  61. Alexa K, Choe S, Hirsch N, Etheridge L, Laver E, SAGERSTROM C. Maternal and zygotic aldh1a2 activity is required for pancreas development in zebrafish. PLoS ONE. 2009;4:e8261 pubmed publisher
    ..We conclude that Aldh1a2 is the primary Aldh acting during pancreas development and that maternal Aldh1a2 activity persists in aldh1a2(um22) and aldh1a2(i26) mutant embryos...
  62. Ellis H. The last year before the dawn of antibiotics. Br J Hosp Med (Lond). 2009;70:475 pubmed
    ..Volume one of the Lancet for that year, for example, contains no less than four papers on different trials of treatment for streptococcal infection as well as a long and learned leading article...
  63. Degawa M, Miura S, Hashimoto Y. Androgen-dependent renal microsomal cytochrome P-450 responsible for N-hydroxylation and mutagenic activation of 3-methoxy-4-aminoazobenzene in the BALB/c mouse. Cancer Res. 1990;50:2729-33 pubmed
    ..These results indicate that the kidney contains an androgen-dependent microsomal 3-MeO-AAB hydroxylase which is different from an isozyme present in the liver and which is a new type of cytochrome P-450 isozyme...
  64. Reyns T, Fraselle S, Laza D, Van Loco J. Rapid method for the confirmatory analysis of chrysoidine in aquaculture products by ultra-performance liquid chromatography-tandem mass spectrometry. Biomed Chromatogr. 2010;24:982-9 pubmed publisher
    ..The applicability of the method was shown in the analysis of more than 50 unknown samples in the framework of a monitoring program...
  65. Kojima M, Morita T, Shirai T, Degawa M, Tada M. Immunological detection and quantitation of DNA adducts formed by 4-aminoazobenzene species in vivo. Jpn J Cancer Res. 1992;83:78-85 pubmed
    ..Immunohistochemical staining indicated that these antibodies bind specifically to nuclear components of the liver in rats given either 3-MeO-AAB or 2-MeO-AAB at the dose of 50 mg/kg body weight...
  66. Yoon K, Burgess D. Effect of nonionic surfactant on transport of model drugs in emulsions. Pharm Res. 1996;13:433-9 pubmed
    ..Mineral oil was chosen as the oil phase and the nonionic surfactant, polyoxyethylene oleyl ether (Brij 97) as the emulsifier...
  67. Degawa M, Matsuda K, Arai H, Hashimoto Y. Lead nitrate inhibits the induction of CYP1A mRNAs by aromatic amines but not by aryl hydrocarbons in the rat liver. J Biochem. 1996;120:547-51 pubmed
  68. Seidenari S, Mantovani L, Manzini B, Pignatti M. Cross-sensitizations between azo dyes and para-amino compound. A study of 236 azo-dye-sensitive subjects. Contact Dermatitis. 1997;36:91-6 pubmed
    ..Cross-sensitizations between azo dyes and para-amino compounds can partially be explained on the basis of structural affinities...
  69. Alsop D, Matsumoto J, Brown S, Van der Kraak G. Retinoid requirements in the reproduction of zebrafish. Gen Comp Endocrinol. 2008;156:51-62 pubmed
  70. Chidambaram N, Burgess D. Mathematical modeling of surface-active and non-surface-active drug transport in emulsion systems. AAPS PharmSci. 2000;2:E31 pubmed
    ..The oil/continuous phase partitioning rates (k1) and the membrane transport rates (k2) were estimated. The predicted data were consistent with the experimental data for both the surface-active and non- surface-active models...
  71. Lerner B. Scientific evidence versus therapeutic demand: the introduction of the sulfonamides revisited. Ann Intern Med. 1991;115:315-20 pubmed
    ..Given the relaxation of FDA regulations, this method of drug evaluation may again become more commonplace...
  72. Miura S, Degawa M, Hashimoto Y. Renal and hepatic microsomal enzymes responsible for bioactivation of 3-methoxy-4-aminoazobenzene in the rodent. Biochem Pharmacol. 1991;42:1655-9 pubmed
    ..These results indicate that the renal and hepatic enzymes responsible for the metabolic activation of 3-MeO-AAB differed among different species of rodent animals in terms of their activity and inducibility with cytochrome P450 inducers...
  73. Sandhu P, Chipman J. Lack of release from hepatocytes in vitro or excretion in vivo of mutagenic chrysoidine metabolites. Toxicol Lett. 1991;58:43-50 pubmed
    ..The ultimate mutagenic form(s) are therefore unlikely to be acetoxyarylamines...