iofetamine

Summary

Summary: An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.

Top Publications

  1. Inoue K, Ito H, Nakagawa M, Goto R, Yamazaki T, Fukuda H. Regional differences in distribution volume of I-123 IMP in the human brain: effect on CBF calculated by ARG method. Ann Nucl Med. 2002;16:311-6 pubmed
    ..Our purpose was to evaluate regional differences in Vd in the human brain, or possible effects of regional differences in Vd on CBF calculated by the ARG method...
  2. Ishii K, Kanda T, Uemura T, Miyamoto N, Yoshikawa T, Shimada K, et al. Computer-assisted diagnostic system for neurodegenerative dementia using brain SPECT and 3D-SSP. Eur J Nucl Med Mol Imaging. 2009;36:831-40 pubmed publisher
    ..To develop a computer-assisted automated diagnostic system to distinguish among Alzheimer disease (AD), dementia with Lewy bodies (DLB), and other degenerative disorders in patients with mild dementia...
  3. Gyulai L, Alavi A, Broich K, Reilley J, Ball W, Whybrow P. I-123 iofetamine single-photon computed emission tomography in rapid cycling bipolar disorder: a clinical study. Biol Psychiatry. 1997;41:152-61 pubmed
    The regional distribution of I-123 iofetamine (IMP) in the brain of 12 patients with rapid cycling bipolar disorder was studied by single-photon computed emission tomography imaging...
  4. Temma T, Magata Y, Mukai T, Kitano H, Konishi J, Saji H. Availability of N-isopropyl-p-[125I]iodoamphetamine (IMP) as a practical cerebral blood flow (CBF) indicator in rats. Nucl Med Biol. 2004;31:811-4 pubmed
    ..The results indicate that DUR of [125I]IMP at 5 min after injection in rats is a useful and practical indicator of CBF since neither arterial blood sampling nor metabolite correction is necessary...
  5. Chiba Y, Iseki E, Fujishiro H, Ota K, Kasanuki K, Suzuki M, et al. Early differential diagnosis between Alzheimer's disease and dementia with Lewy bodies: Comparison between (18)F-FDG PET and (123)I-IMP SPECT. Psychiatry Res Neuroimaging. 2016;249:105-12 pubmed publisher
    ..Both FDG PET and IMP SPECT would be useful for the differential diagnosis between AD and DLB. For the differential diagnosis of MCI-AD versus MCI-DLB, FDG PET would be more useful than IMP SPECT. ..
  6. Ogasawara K, Ito H, Sasoh M, Okuguchi T, Kobayashi M, Yukawa H, et al. Quantitative measurement of regional cerebrovascular reactivity to acetazolamide using 123I-N-isopropyl-p-iodoamphetamine autoradiography with SPECT: validation study using H2 15O with PET. J Nucl Med. 2003;44:520-5 pubmed
    ..To validate the accuracy of (123)I-IMP-ARG for quantifying regional cerebrovascular reactivity (rCVR) to acetazolamide, we compared rCVR determined using (123)I-IMP-ARG with that determined using H(2)(15)O PET...
  7. Asazu A, Hayashi M, Arai M, Kumai Y, Akagi H, Okayama K, et al. [Application of N-isopropyl-p-[123I] iodoamphetamine quantification of regional cerebral blood flow using iterative reconstruction methods: selection of the optimal reconstruction method and optimization of the cutoff frequency of the preprocessing f. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2013;69:535-44 pubmed
    ..75-0.85 cycles/cm, which is higher than the frequency used in image reconstruction by the ordinary FBP method...
  8. Shiga T, Kubo N, Takano A, Kobayashi J, Takeda Y, Nakamura F, et al. The effect of scatter correction on 123I-IMP brain perfusion SPET with the triple energy window method in normal subjects using SPM analysis. Eur J Nucl Med Mol Imaging. 2002;29:342-5 pubmed
    ..This needs to be recognised for adequate interpretation of IMP brain perfusion SPET after scatter correction...
  9. Ito H, Sato T, Odagiri H, Inoue K, Shidahara M, Suhara T, et al. Brain and whole body distribution of N-isopropyl-4-iodoamphetamine (I-123) in humans: comparison of radiopharmaceuticals marketed by different companies in Japan. Ann Nucl Med. 2006;20:493-8 pubmed
    ..Two IMPs (IMPA and IMPB) produced by different radiopharmaceutical companies are marketed in Japan. In the present study, whole-body distributions including brain and blood of the two IMPs were compared in the same human subjects...

More Information

Publications62

  1. Yamaguchi S, Takeuchi Y, Nakayama K, Arakawa M, Shigemori M. [Two surgically treated cases with dural arteriovenous malformation in the anterior cranial fossa]. No Shinkei Geka. 2005;33:1219-26 pubmed
    ..Surgical obliteration of fistulae is reasonable even in the dAVF of the anterior cranial fossa with ischemic onset...
  2. Kobayashi M, Kiyono Y, Maruyama R, Mori T, Kawai K, Okazawa H. Development of an H(2)(15)O steady-state method combining a bolus and slow increasing injection with a multiprogramming syringe pump. J Cereb Blood Flow Metab. 2011;31:527-34 pubmed publisher
    ..01x-0.37, r(2)=0.97). The H(2)(15)O steady-state method with a continuously increasing injection is useful for CBF measurement in small animal studies, especially when multiple scans are required in the same animal...
  3. Ogasawara K, Ogawa A, Terasaki K, Shimizu H, Tominaga T, Yoshimoto T. Use of cerebrovascular reactivity in patients with symptomatic major cerebral artery occlusion to predict 5-year outcome: comparison of xenon-133 and iodine-123-IMP single-photon emission computed tomography. J Cereb Blood Flow Metab. 2002;22:1142-8 pubmed
  4. Ko T, Utanohara Y, Suzuki Y, Kurihara M, Iguchi N, Umemura J, et al. A preliminary feasibility study of simultaneous dual-isotope imaging with a solid-state dedicated cardiac camera for evaluating myocardial perfusion and fatty acid metabolism. Heart Vessels. 2016;31:38-45 pubmed publisher
    ..Compared with conventional (201)TlCl/(123)I-BMIPP dual-isotope imaging, the use of (99m)Tc-MIBI instead of (201)TlCl improves image quality as well as lowers radiation exposure. ..
  5. Watanabe Y, Nakano T, Yutani K, Nishimura H, Kusuoka H, Nakamura H, et al. Detection of viable cortical neurons using benzodiazepine receptor imaging after reversible focal ischaemia in rats: comparison with regional cerebral blood flow. Eur J Nucl Med. 2000;27:308-13 pubmed
    ..These results suggest that benzodiazepine receptor imaging is superior to regional cerebral blood flow imaging for the detection of viable cortical neurons in both the acute and subacute phases of ischaemia...
  6. Saura H, Ogasawara K, Suzuki T, Kuroda H, Yamashita T, Kobayashi M, et al. Effect of combination therapy with the angiotensin receptor blocker losartan plus hydrochlorothiazide on brain perfusion in patients with both hypertension and cerebral hemodynamic impairment due to symptomatic chronic major cerebral artery steno-occ. Cerebrovasc Dis. 2012;33:354-61 pubmed publisher
  7. Matsuda H, Tsuji S, Oba H, Kinuya K, Terada H, Sumiya H, et al. Double tracer autoradiographic method for sequential evaluation of regional cerebral perfusion. Am J Physiol Imaging. 1989;4:131-5 pubmed
    ..The results suggest that this technique is of potential use in the study of neuropharmacological effects applied during the experiment...
  8. Shiga T, Kaji T, Kohno T, Kageyama H, Katoh C, Hatazawa J, et al. [Evaluation of the product-specific standard input function for the IMP-ARG method]. Kaku Igaku. 2007;44:1-7 pubmed
  9. Murase K, Inoue T, Fujioka H, Yamamoto Y, Ikezoe J. Double-injection method for sequentially measuring cerebral blood flow with N-isopropyl-(123I)p-iodoamphetamine. Ann Nucl Med. 2000;14:441-52 pubmed
    ..The response of CBF to acetazolamide challenge was also assessed by the above four methods. The knowledge gained by this study may assist in selecting a method for sequentially measuring CBF with a double injection of IMP...
  10. Kurita A, Yonezawa J, Suzuki M, Kawaguchi S, Ito Y, Inoue K. [Changes in visual event-related potentials and SPECT in dissociative amnesia]. Rinsho Shinkeigaku. 2004;44:14-9 pubmed
    ..While dissociative amnesia has been understood as psychogenic nature, both ERPs and SPECT are quite important tools to understand the association between the psychological phenomenon and biological changes of the brain in this disorder...
  11. Tatsu Y, Narabayashi I, Watanabe M, Komori T, Aratani T, Doi K, et al. Serial changes in N-isopropyl-p[125I]-iodoamphetamine in mouse lung observed with a confocal laser scanning microscope. Ann Nucl Med. 2000;14:235-8 pubmed
  12. Sáez Zea C, Escamilla Sevilla F, Martínez Simón J, Arnedo M, Minguez Castellanos A. Neuropsychological deficits associated with destruction of the right nigrostriatal pathway. J Int Neuropsychol Soc. 2013;19:729-34 pubmed publisher
    ..The more complex neuropsychological dysfunction developed by other PD patients must therefore be related to the additional involvement of other brain structures...
  13. Honda M, Ezaki Y, Kitagawa N, Tsutsumi K, Ogawa Y, Nagata I. Quantification of the regional cerebral blood flow and vascular reserve in moyamoya disease using split-dose iodoamphetamine I 123 single-photon emission computed tomography. Surg Neurol. 2006;66:155-9; discussion 159 pubmed
    ..We quantified the rCBF and regional vascular reserve (CVR) in adult patients with moyamoya disease before and after surgery using IMP I 123 SPECT...
  14. Ito H, Inoue K, Goto R, Kinomura S, Taki Y, Okada K, et al. Database of normal human cerebral blood flow measured by SPECT: I. Comparison between I-123-IMP, Tc-99m-HMPAO, and Tc-99m-ECD as referred with O-15 labeled water PET and voxel-based morphometry. Ann Nucl Med. 2006;20:131-8 pubmed
    ..The regional distribution of tissue fractions of gray matter determined by voxel-based morphometry was also compared with SPECT and PET CBF distributions...
  15. Bryan R, Duckrow R. Radial columns in autoradiographs generated from tracer methods for measuring cerebral cortical blood flow. Am J Physiol. 1995;269:H583-9 pubmed
    ..We conclude that capillary blood flow in the cortex is not organized in radial columns of higher and lower flow. The results support the idea that the flow tracers are removed from blood primarily in the penetrating arterioles...
  16. Iseya O, Mihara T, Suzuki K, Miyamae T, Matsuda H. [Evaluation of the 123I-IMP Patlak plot method using the pulmonary differential curve as an input function: a comparison with cerebral blood flow (CBF) determined by the noninvasive micro-sphere (NIMS) method]. Kaku Igaku. 2003;40:163-74 pubmed
    ..These results indicate that the 123I-IMP Patlak plot method with a wide-field gamma camera is clinically applicable as a simpler noninvasive technique for measuring cerebral blood flow even when a simple input function is used...
  17. Onishi H, Hatazawa J, Nakagawara J, Ito K, Ha Kawa S, Masuda Y, et al. [Availability of normal database by single photon emission computed tomography system with use of 3 dimensional-stereotactic surface projections]. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2012;68:1608-16 pubmed
    ..We standardized the acquisition and reconstruction conditions, evaluated Z scores using patient data (PD) and examined each compensation effect...
  18. Pouliot M, Deschenes M, Hétu S, Chemtob S, Lesk M, Couture R, et al. Quantitative and regional measurement of retinal blood flow in rats using N-isopropyl-p-[14C]-iodoamphetamine ([14C]-IMP). Exp Eye Res. 2009;89:960-6 pubmed publisher
    ..This technique is a powerful tool to study how retinal blood flow is regulated in different regions of the rat retina...
  19. Okizaki A, Shuke N, Sato J, Maruyama N, Haneda M, Aburano T. Transient brain hyperperfusion detected with I-123 IMP SPECT in a patient with neuropsychiatric systemic lupus erythematosus. Clin Nucl Med. 2009;34:601-3 pubmed publisher
    ..Two months later, the hyperperfusion was disappeared. The hyperperfusion could be explained by inflammatory changes...
  20. Kuroda H, Ogasawara K, Suzuki T, Chida K, Aso K, Kobayashi M, et al. Accuracy of central benzodiazepine receptor binding potential/cerebral blood flow SPECT imaging for detecting misery perfusion in patients with unilateral major cerebral artery occlusive diseases: comparison with cerebrovascular reactivity to acetazo. Clin Nucl Med. 2012;37:235-40 pubmed publisher
  21. Itoh S, Hiramatsu N, Iwata A, Yoshiya K, Imai S. [Measurements of cerebral blood flow by the noninvasive microsphere method with 123I-IMP and fan beam collimator: comparison with the continuous arterial blood sampling method]. Kaku Igaku. 2001;38:689-98 pubmed
    ..In phantom and clinical studies we investigated the validity of using a fan beam collimator in collecting planar and SPECT raw data...
  22. Okamura N, Arai H, Maruyama M, Higuchi M, Matsui T, Tanji H, et al. Combined Analysis of CSF Tau Levels and [(123)I]Iodoamphetamine SPECT in Mild Cognitive Impairment: Implications for a Novel Predictor of Alzheimer's Disease. Am J Psychiatry. 2002;159:474-6 pubmed
    ..The aim of this study was to establish an objective and reliable index to predict the development of Alzheimer's disease in a large pool of elderly patients with mild cognitive impairment...
  23. Kawabori M, Kuroda S, Kudo K, Terae S, Kaneda M, Nakayama N, et al. Susceptibility-weighted magnetic resonance imaging detects impaired cerebral hemodynamics in the superior sagittal sinus thrombosis--case report. Neurol Med Chir (Tokyo). 2009;49:248-51 pubmed
    ..Susceptibility-weighted imaging can be used as a non-invasive method to monitor the severity of venous congestion caused by cerebral venous sinus thrombosis...
  24. Ogasawara K, Okuguchi T, Sasoh M, Kobayashi M, Yukawa H, Terasaki K, et al. Qualitative versus quantitative assessment of cerebrovascular reactivity to acetazolamide using iodine-123-N-isopropyl-p-iodoamphetamine SPECT in patients with unilateral major cerebral artery occlusive disease. AJNR Am J Neuroradiol. 2003;24:1090-5 pubmed
    ..We attempted to validate the accuracy of qualitative assessment by using SPECT to detect reduced rCVR compared with rCVR determined quantitatively in patients with unilateral major cerebral artery occlusion...
  25. Shibuya N, Tachibana H, Kawabata K, Sugita M. [Memory function in patients with Parkinson's disease: in relation to neuropsychological tests and cerebral blood flow]. Nihon Ronen Igakkai Zasshi. 2001;38:193-200 pubmed
  26. Kubota T, Kato K, Ichihara S, Hirose H. Diagnosis of atypical choroidal malignant melanoma using N-isopropyl-p-[123I]-iodoamphetamine single photon emission computed tomography. Jpn J Ophthalmol. 2006;50:185-7 pubmed
  27. Miyazawa N, Arbab A, Umeda T, Akiyama I. Perfusion CT investigation of chronic internal carotid artery occlusion: comparison with SPECT. Clin Neurol Neurosurg. 2005;108:11-7 pubmed
    ..580, R(2) = 0.337, p < 0.001) and MTT and CBV (r = 0.763, R(2) = 0.582, p < 0.001). Perfusion CT is useful to evaluate the hemodynamic state of patients with chronic major cerebral artery occlusive disorders...
  28. Hamano S. [Developmental outcomes of cryptogenic west syndrome: facused on the alteration of regional cerebral blood flow during ACTH therapy using SPECT study]. No To Hattatsu. 2007;39:181-4 pubmed
  29. Sagiuchi T, Oka H, Utsuki S, Sato K, Kobayashi I, Asano Y, et al. Increased accumulations of N-isopropyl-p-[123I]-iodoamphetamine related to tumefactive multiple sclerosis. Ann Nucl Med. 2005;19:603-6 pubmed
    ..The SPECT findings represent a diagnostic pitfall for distinguishing MS from malignant brain tumors in patients with intracranial tumor-like lesions...
  30. Kobayashi H, Watanabe H, Seino T, Suzuki S, Sato Y. Quantitative imaging of cerebral blood flow using SPECT with 123I-iodoamphetamine in neuropsychiatric systemic lupus erythematosus. J Rheumatol. 2003;30:2075-6 pubmed
  31. Nagaki A, Kobara K, Matsutomo N. [Development of quantification analysis software for measuring regional cerebral blood flow by the modified split-dose method with (123)I-IMP before and after acetazolamide loading]. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2003;59:1573-9 pubmed
    ..Further clinical studies are required to validate our rCBF quantification analysis program for the MSD method...
  32. Kaneko K, Sasaki M, Morioka T, Koga H, Abe K, Sawamoto H, et al. Pre-surgical identification of epileptogenic areas in temporal lobe epilepsy by 123I-iomazenil SPECT: a comparison with IMP SPECT and FDG PET. Nucl Med Commun. 2006;27:893-9 pubmed
  33. Jibiki I, Kubota T, Fujimoto K, Yamaguchi N, Matsuda H, Tsuji S, et al. High reproducibility of regional abnormalities on interictal 123I-IMP SPECT brain scans in adults with partial epilepsy. Eur Arch Psychiatry Clin Neurosci. 1990;240:5-8 pubmed
    ..This high reproducibility supports the usefulness of SPECT scans in the regional diagnosis of epileptic foci...
  34. Shirane S, Sasaki M, Kogure D, Matsuda H, Hashimoto T. Increased ictal perfusion of the thalamus in paroxysmal kinesigenic dyskinesia. J Neurol Neurosurg Psychiatry. 2001;71:408-10 pubmed
    ..This finding suggests that abnormal hyperactivity of thalamic neurons could be responsible for the pathophysiology of paroxysmal kinesigenic dyskinesia in this patient...
  35. Imaizumi M, Kitagawa K, Hashikawa K, Oku N, Teratani T, Takasawa M, et al. Detection of misery perfusion with split-dose 123I-iodoamphetamine single-photon emission computed tomography in patients with carotid occlusive diseases. Stroke. 2002;33:2217-23 pubmed
    ..In clinical practice, the detection of patients with misery perfusion through the use of widely available, noninvasive, and cost-effective modalities such as single-photon emission computed tomography (SPECT) is extremely important...
  36. Arbab A, Aoki S, Toyama K, Araki T, Miyazawa N, Kumagai H, et al. Optimal inversion time for acquiring flow-sensitive alternating inversion recovery images to quantify regional cerebral blood flow. Eur Radiol. 2002;12:2950-6 pubmed
    ..The FAIR images with TI value of 1400 ms gave more comparable CBF. A TI value of 1400 ms might be optimum for 1.5-T MR strength to get high quality FAIR images and comparable CBF...
  37. Yoshimura M, Kanesaka N, Saito K, Koizumi K, Tokuuye K, Goto H. Diagnosis of uveal malignant melanoma by a new semiquantitative assessment of N-isopropyl-p-[123I]-iodoamphetamine. Jpn J Ophthalmol. 2011;55:148-54 pubmed publisher
    ..To semiquantify the uptake of N-isopropyl-p-[(123)I]-iodoamphetamine (I-123 IMP) in patients with uveal malignant melanoma reproducibly and objectively...
  38. Goto H. Clinical efficacy of 123I-IMP SPECT for the diagnosis of malignant uveal melanoma. Int J Clin Oncol. 2004;9:74-8 pubmed
  39. Kubota T, Ushijima Y, Yamada K, Okuyama C, Kizu O, Nishimura T. Diagnosis of Alzheimer's disease using brain perfusion SPECT and MR imaging: which modality achieves better diagnostic accuracy?. Eur J Nucl Med Mol Imaging. 2005;32:414-21 pubmed
    ..The purpose of this study was to compare the accuracy of MR imaging and brain perfusion single-photon emission tomography (SPECT) in diagnosing Alzheimer's disease (AD)...
  40. Kurisu R, Ogura T, Takikawa S, Saito H, Nakazawa M, Iida H. [Estimation and optimization of the use of standard arterial input function for split-dose administration of N-isopropyl-p[123I]iodoamphetamine]. Kaku Igaku. 2002;39:13-20 pubmed
  41. Imai M, Kurihara M, Kumagai K, Maekawa K. [Early 123I-IMP SPECT in patients with epilepsy]. No To Hattatsu. 1991;23:458-64 pubmed
    ..This was also seen in some cases with normal CT imaging. The results suggest that the hemodynamic pathophysiology of the brain and the indications of therapeutic effectiveness in epilepsy are shown more accurately by SPECT than CT...
  42. Naganuma Y, Konishi T, Hongou K, Murakami M, Yamatani M, Okada T. [A case of progeria syndrome with cerebral infarction]. No To Hattatsu. 1990;22:71-6 pubmed
    ..A slowing of back ground on EEG also correlated well with clinical symptoms. It was necessary to examine the possibility of cerebrovascular involvement in progeria...
  43. Moriwaki H, Uno H, Nagakane Y, Hayashida K, Miyashita K, Naritomi H. Losartan, an angiotensin II (AT1) receptor antagonist, preserves cerebral blood flow in hypertensive patients with a history of stroke. J Hum Hypertens. 2004;18:693-9 pubmed
    ..Thus, CBF was preserved despite the reduction in BP. We consider the use of losartan is advantageous for hypertensive patients with a history of stroke in whom autoregulation of CBF is potentially impaired...
  44. Sato Y, Ogasawara K, Kuroda H, Suzuki T, Chida K, Fujiwara S, et al. Preoperative central benzodiazepine receptor binding potential and cerebral blood flow images on SPECT predict development of new cerebral ischemic events and cerebral hyperperfusion after carotid endarterectomy. J Nucl Med. 2011;52:1400-7 pubmed publisher
  45. Tosaka M, Fukasawa Y, Takahashi A, Sasaki A, Saito N. Incidentally detected parafalcine chondrosarcoma. Acta Neurochir (Wien). 2005;147:795-9; discussion 799 pubmed
    ..SPECT using (201)TlCl and (123)I-IMP may be useful to discriminate parafalcine low-grade chondrosarcoma from meningioma or other tumours originating in this region...
  46. Abe S, Kato K, Takahashi Y, Fujita N, Yamashita M, Shinoda M, et al. Estimation of ¹²³I-IMP arterial blood activity using ¹²³I-IMP acquisition data from the lungs and brain without any blood sampling: validation of its usefulness for quantification of regional cerebral blood flow. Clin Nucl Med. 2012;37:258-63 pubmed publisher
    ..Both groups of the mean CBF values were also compared with those measured by O-15 H?O PET ARG method...
  47. Yoshimura M, Akata S, Saito K, Shindo H, Park J, Hirose H, et al. Characterization of an orbital melanoma and mucosa associated lymphoid tissue (MALT) lymphoma by dual phase N-isopropyl-p-I-123 iodoamphetamine. Clin Nucl Med. 2007;32:638-9 pubmed
    ..In the same way, magnetic resonance imaging examination was undertaken 3 times. Both lesions were obvious, but the findings were entirely unchanged in each examination...
  48. Nagai T, Kajita Y, Maesawa S, Nakatsubo D, Yoshida K, Kato K, et al. Preoperative regional cerebral blood flow and postoperative clinical improvement in patients with Parkinson's disease undergoing subthalamic nucleus deep brain stimulation. Neurol Med Chir (Tokyo). 2012;52:865-72 pubmed
    ..8 ± 6.2 ml/100 g/min in the frontal lobe. This study indicated that rCBF in patients with PD might be related to their clinical features, suggesting that quantitative mapping of rCBF may be useful for predicting surgical outcome...
  49. Oku T, Nogami K, Koizumi H, Ishihara H, Kato S, Fujisawa H, et al. External carotid artery stenting and superficial temporal artery to middle cerebral artery anastomosis for internal carotid artery occlusion with external carotid artery severe stenosis: case report. Neurol Med Chir (Tokyo). 2012;52:906-9 pubmed
    ..This case suggests external CAS together with STA-MCA anastomosis is a good therapeutic option for a patient with symptomatic ICA occlusion and severe stenosis of the ipsilateral ECA if external CEA is difficult to perform...
  50. Haga S, Morioka T, Shimogawa T, Akiyama T, Murao K, Kanazawa Y, et al. Arterial Spin Labeling Perfusion Magnetic Resonance Image with Dual Postlabeling Delay: A Correlative Study with Acetazolamide Loading (123)I-Iodoamphetamine Single-Photon Emission Computed Tomography. J Stroke Cerebrovasc Dis. 2016;25:1-6 pubmed publisher
  51. Fujimura M, Mugikura S, Shimizu H, Tominaga T. [Diagnostic value of perfusion-weighted MRI for evaluating postoperative alteration of cerebral hemodynamics following STA-MCA anastomosis in patients with moyamoya disease]. No Shinkei Geka. 2006;34:801-9 pubmed
    ..But little is known about the changes of CBF and its effect on neurological status during the acute stage after direct bypass for moyamoya disease...
  52. Ogura K, Fujii T, Abe N, Hosokai Y, Shinohara M, Fukuda H, et al. Regional cerebral blood flow and abnormal eating behavior in Prader-Willi syndrome. Brain Dev. 2013;35:427-34 pubmed publisher
    ..Correlation analyses were also performed to examine the relationship between rCBF and altered eating behavior in PWS individuals...
  53. Mori K, Maeda M, Asegawa S, Iwata J. Quantitative local cerebral blood flow change after cerebrospinal fluid removal in patients with normal pressure hydrocephalus measured by a double injection method with N-isopropyl-p-[(123)I] iodoamphetamine. Acta Neurochir (Wien). 2002;144:255-62; discussion 262-3 pubmed
    ..This new quantitative CSF removal test could be useful for selecting good candidates for CSF shunting surgery among patients with NPH...