rosaniline dyes

Summary

Summary: Compounds that contain the triphenylmethane aniline structure found in rosaniline. Many of them have a characteristic magenta color and are used as COLORING AGENTS.

Top Publications

  1. Notomi S, Hisatomi T, Kanemaru T, Takeda A, Ikeda Y, Enaida H, et al. Critical involvement of extracellular ATP acting on P2RX7 purinergic receptors in photoreceptor cell death. Am J Pathol. 2011;179:2798-809 pubmed publisher
    ..Our results encourage the potential application of Brilliant Blue G as a novel neuroprotective agent in retinal diseases or similar neurodegenerative pathologies linked to excessive extracellular ATP...
  2. Fujisawa Y, Nakamura Y, Kawachi Y, Otsuka F. Indocyanine green fluorescence-navigated sentinel node biopsy showed higher sensitivity than the radioisotope or blue dye method, which may help to reduce false-negative cases in skin cancer. J Surg Oncol. 2012;106:41-5 pubmed publisher
    ..We tested a new lymphatic navigation method using indocyanine green fluorescence imaging (ICG-FI) to detect such "occult" SLNs...
  3. Iwamaru Y, Takenouchi T, Murayama Y, Okada H, Imamura M, Shimizu Y, et al. Anti-prion activity of Brilliant Blue G. PLoS ONE. 2012;7:e37896 pubmed publisher
  4. Franco E, Friedrichs E, Kim J, Jungmann R, Murray R, Winfree E, et al. Timing molecular motion and production with a synthetic transcriptional clock. Proc Natl Acad Sci U S A. 2011;108:E784-93 pubmed publisher
    ..Understanding how to design effective insulation between biochemical subsystems will be critical for the synthesis of larger and more complex systems...
  5. Liu L, Parrett B, Jenkins T, Lee W, Morita E, Treseler P, et al. Selective sentinel lymph node dissection for melanoma: importance of harvesting nodes with lower radioactive counts without the need for blue dye. Ann Surg Oncol. 2011;18:2919-24 pubmed publisher
  6. Wong H, Qi W, Choi H, Fernandez E, Kwon I. A safe, blood-brain barrier permeable triphenylmethane dye inhibits amyloid-? neurotoxicity by generating nontoxic aggregates. ACS Chem Neurosci. 2011;2:645-57 pubmed publisher
    ..Furthermore, key structural features of BBG identified through structure-function studies can open new avenues into therapeutic design for combating AD...
  7. Awad D, Schrader I, Bartok M, Mohr A, Gabel D. Comparative toxicology of trypan blue, brilliant blue G, and their combination together with polyethylene glycol on human pigment epithelial cells. Invest Ophthalmol Vis Sci. 2011;52:4085-90 pubmed publisher
  8. Uhara H, Yamazaki N, Takata M, Inoue Y, Sakakibara A, Nakamura Y, et al. Applicability of radiocolloids, blue dyes and fluorescent indocyanine green to sentinel node biopsy in melanoma. J Dermatol. 2012;39:336-8 pubmed publisher
    ..Allergic reactions were not reported with any of the tracers. (99m)Tc-tin colloid, (99m)Tc-phytate, PBV and indocyanine green are useful tracers for SN mapping...
  9. Iriyama A, Kadonosono K, Tamaki Y, Yanagi Y. Effect of Brilliant Blue G on the retinal ganglion cells of rats. Retina. 2012;32:613-6 pubmed publisher
    ..To investigate the effects of Brilliant Blue G (BBG) on rat retinal ganglion cells (RGCs), both in vitro and in vivo...

More Information

Publications62

  1. Shukla D, Kalliath J, Neelakantan N, Naresh K, Ramasamy K. A comparison of brilliant blue G, trypan blue, and indocyanine green dyes to assist internal limiting membrane peeling during macular hole surgery. Retina. 2011;31:2021-5 pubmed publisher
    ..To compare surgical outcomes with three dyes, brilliant blue G (BBG), trypan blue (TB) and indocyanine green (ICG), used to facilitate internal limiting membrane peeling during macular hole surgery...
  2. Dong W, Wang T, Wang F, Zhang J. Simple, time-saving dye staining of proteins for sodium dodecyl sulfate-polyacrylamide gel electrophoresis using Coomassie blue. PLoS ONE. 2011;6:e22394 pubmed publisher
    ..Considering the speed, simplicity, and low cost, the dye stain may be of more practical value than other dye-based protein stains in routine proteomic research...
  3. Wang J, Qiao M, Wei K, Ding J, Liu Z, Zhang K, et al. Decolorizing activity of malachite green and its mechanisms involved in dye biodegradation by Achromobacter xylosoxidans MG1. J Mol Microbiol Biotechnol. 2011;20:220-7 pubmed publisher
    ..The extracellular biodegradation was likely attributable to the secretion of extracellular proteases and some heat-resistant compounds...
  4. Neves R, Reynolds B, Hazard S, Saunders B, Mackay D. Increased post-operative complications with methylene blue versus lymphazurin in sentinel lymph node biopsies for skin cancers. J Surg Oncol. 2011;103:421-5 pubmed publisher
    ..Sentinel lymph node biopsy (SNLB) is the standard of care in staging of melanoma and other skin cancers. Early studies used lymphazurin (LZ) for SLNB. A national shortage of LZ promoted methylene blue (MB) as an alternate stain...
  5. Kumar A, Gogia V, Shah V, Nag T. Comparative evaluation of anatomical and functional outcomes using brilliant blue G versus triamcinolone assisted ILM peeling in macular hole surgery in Indian population. Graefes Arch Clin Exp Ophthalmol. 2011;249:987-95 pubmed publisher
    ..To compare anatomical and functional outcomes using brilliant blue G (BBG) vs triamcinolone acetonide (TA)-assisted ILM peeling in macular hole surgery (MHS)...
  6. Májek P, Riedelová Reicheltová Z, Suttnar J, Dyr J. Staining of proteins for 2D SDS-PAGE using Coomassie Blue--speed versus sensitivity?. Electrophoresis. 2013;34:1972-5 pubmed
    ..PLoS One 2011, 6, e22394) seems to be less sensitive than colloidal Coomassie staining when the number of detected spots is the evaluating criterion. No obvious influence of gel boiling on the protein identification was observed...
  7. Wang X, Li X, Li Y. A modified Coomassie Brilliant Blue staining method at nanogram sensitivity compatible with proteomic analysis. Biotechnol Lett. 2007;29:1599-603 pubmed
    ..The improved method is more sensitive than Blue Silver and more convenient than the Silver protocol. Mass spectrometry results confirmed that it is suitable for subsequent proteomic research...
  8. Cervera E, Diaz Llopis M, Salom D, Udaondo P. [High dose intravitreal brilliant blue G]. Arch Soc Esp Oftalmol. 2007;82:473 pubmed
  9. Banaei N, Kincaid E, Lin S, Desmond E, Jacobs W, Ernst J. Lipoprotein processing is essential for resistance of Mycobacterium tuberculosis to malachite green. Antimicrob Agents Chemother. 2009;53:3799-802 pubmed publisher
    ..In summary, lipoprotein processing by LspA is essential for resistance of M. tuberculosis to malachite green. A cell wall permeability defect is likely responsible for the hypersensitivity of lspA mutant to malachite green...
  10. Culp S, Mellick P, Trotter R, Greenlees K, Kodell R, Beland F. Carcinogenicity of malachite green chloride and leucomalachite green in B6C3F1 mice and F344 rats. Food Chem Toxicol. 2006;44:1204-12 pubmed
    ..Female mice fed leucomalachite green had a dose-related increasing trend in the incidence of hepatocellular adenoma or carcinoma, with the incidence being significant in the highest dose group...
  11. Sugiyama T, Oku H, Shibata M, Fukuhara M, Yoshida H, Ikeda T. Involvement of P2X7 receptors in the hypoxia-induced death of rat retinal neurons. Invest Ophthalmol Vis Sci. 2010;51:3236-43 pubmed publisher
    ..To investigate the hypoxia-induced death of rat retinal neurons and to determine whether P2X(7) activation is involved in this type of neuronal death...
  12. Mitrowska K, Posyniak A, Zmudzki J. Determination of malachite green and leucomalachite green residues in water using liquid chromatography with visible and fluorescence detection and confirmation by tandem mass spectrometry. J Chromatogr A. 2008;1207:94-100 pubmed publisher
    ..These findings prove that N-demethylated products of MG and LMG, reported as potential carcinogens, may be formed in living fish organisms not only during enzymatic action but also during photo-oxidative degradation in water...
  13. Andersen W, Turnipseed S, Karbiwnyk C, Lee R, Clark S, Rowe W, et al. Multiresidue method for the triphenylmethane dyes in fish: Malachite green, crystal (gentian) violet, and brilliant green. Anal Chim Acta. 2009;637:279-89 pubmed publisher
    ..The limits of detection for CV, BG, and MG were in the range of 0.07-0.24 ngg(-1) (ppb) for the two different instrumental methods. This methodology was applied to the analysis of catfish treated with CV and BG...
  14. Henrich P, Haritoglou C, Meyer P, Ferreira P, Schotzau A, Katamay R, et al. Anatomical and functional outcome in brilliant blue G assisted chromovitrectomy. Acta Ophthalmol. 2010;88:588-93 pubmed publisher
    ..To evaluate the potential of brilliant blue G (BBG) for intraoperative staining of the inner limiting membrane (ILM) with respect to staining properties and surgical outcome...
  15. Hu H, Lu W, Zhang M, Zhang X, Argall A, Patel S, et al. Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo. Exp Eye Res. 2010;91:425-32 pubmed publisher
    ..This implies that the balance between extracellular ATP and its protective metabolite adenosine can influence ganglion cell survival in the living eye. ..
  16. Raut C, Hunt K, Akins J, Daley M, Ross M, Singletary S, et al. Incidence of anaphylactoid reactions to isosulfan blue dye during breast carcinoma lymphatic mapping in patients treated with preoperative prophylaxis: results of a surgical prospective clinical practice protocol. Cancer. 2005;104:692-9 pubmed
    ..In December 2001, the authors began administering a prophylactic regimen before dye injection to determine whether prophylaxis reduced the incidence of life-threatening reactions...
  17. Oliveira S, Lopes T, Tóth I, Rangel A. Development of a gas diffusion multicommuted flow injection system for the determination of sulfur dioxide in wines, comparing malachite green and pararosaniline chemistries. J Agric Food Chem. 2009;57:3415-22 pubmed publisher
    ..With regard to the two tested chemistries, 18 wines were analyzed and the results achieved by the pararosaniline reaction compared better with those furnished by the recommended procedure...
  18. Kim M, Kim Y, Park H, Lee J, Kwak S, Jung W, et al. Structural insight into bioremediation of triphenylmethane dyes by Citrobacter sp. triphenylmethane reductase. J Biol Chem. 2008;283:31981-90 pubmed publisher
  19. Sandhu S, Farag E, Argalious M. Anaphylaxis to isosulfan blue dye during sentinel lymph node biopsy. J Clin Anesth. 2005;17:633-5 pubmed
    ..Isosulfan blue dye can act as an antigen, causing a full-blown intraoperative anaphylactic reaction. Early recognition and aggressive hemodynamic interventions can reduce morbidity and mortality...
  20. Liu Y, Truini C, Ariyan S. A randomized study comparing the effectiveness of methylene blue dye with lymphazurin blue dye in sentinel lymph node biopsy for the treatment of cutaneous melanoma. Ann Surg Oncol. 2008;15:2412-7 pubmed publisher
    ..The purpose of this study of SLN biopsies was to compare the effectiveness of MB with that of LB dye...
  21. Enaida H, Hisatomi T, Hata Y, Ueno A, Goto Y, Yamada T, et al. Brilliant blue G selectively stains the internal limiting membrane/brilliant blue G-assisted membrane peeling. Retina. 2006;26:631-6 pubmed
    ..To report the use of the dye brilliant blue G (BBG) for staining of the internal limiting membrane (ILM) during macular hole (MH) and epiretinal membrane (ERM) surgery...
  22. Andersen W, Turnipseed S, Roybal J. Quantitative and confirmatory analyses of malachite green and leucomalachite green residues in fish and shrimp. J Agric Food Chem. 2006;54:4517-23 pubmed
    ..0 ng/g for LC-VIS and 0.25 ng/g for LC-MSn. Incurred tissues from catfish, trout, tilapia, and salmon that had been treated with MG were also extracted and analyzed as part of this study...
  23. Goyal A, Newcombe R, Chhabra A, Mansel R. Factors affecting failed localisation and false-negative rates of sentinel node biopsy in breast cancer--results of the ALMANAC validation phase. Breast Cancer Res Treat. 2006;99:203-8 pubmed
    ..A major aim of this prospective multicentre validation study was to quantify detection and false-negative rates of SLNB and evaluate factors influencing them...
  24. Bose B, Motiwale L, Rao K. DNA damage and G2/M arrest in Syrian hamster embryo cells during Malachite green exposure are associated with elevated phosphorylation of ERK1 and JNK1. Cancer Lett. 2005;230:260-70 pubmed
    ..The present study indicates that elevated phosphorylation of ERK1 and JNK1 and an increase in G2/M phase and apoptotic cells seems to be the changes associated with MG exposure to SHE cells in primary culture...
  25. Januschowski K, Mueller S, Spitzer M, Lueke M, Bartz Schmidt K, Szurman P. The effects of the intraocular dye brilliant blue G (BBG) mixed with varying concentrations of glucose on retinal function in an isolated perfused vertebrate retina. Graefes Arch Clin Exp Ophthalmol. 2011;249:483-9 pubmed publisher
    ..This study investigated the effect of 0.4 ml BBG (Brilliant Peel™ 0.25 mg/ml, Fluoron, Ulm, Germany) mixed with various glucose concentrations on the retina in an pseudo in vivo model..
  26. van de Riet J, Murphy C, Pearce J, Potter R, Burns B. Determination of malachite green and leucomalachite green in a variety of aquacultured products by liquid chromatography with tandem mass spectrometry detection. J AOAC Int. 2005;88:744-9 pubmed
    ..The recommended method is simple, rapid, and specific for monitoring residues of MG and LMG in a number of aquatic species...
  27. Yasumitsu H, Ozeki Y, Kawsar S, Fujii Y, Sakagami M, Matuo Y, et al. RAMA stain: a fast, sensitive and less protein-modifying CBB R250 stain. Electrophoresis. 2010;31:1913-7 pubmed publisher
    ..Finally, MS analyses of RAMA-stained protein bands were revealed not to have been methylated...
  28. Stammati A, Nebbia C, Angelis I, Albo A, Carletti M, Rebecchi C, et al. Effects of malachite green (MG) and its major metabolite, leucomalachite green (LMG), in two human cell lines. Toxicol In Vitro. 2005;19:853-8 pubmed
    ..By contrast, LMG disclosed, in both cell lines, a lower cytotoxicity compared to MG. These results also show that HEp-2 cells are more sensitive than intestinal cells to the toxic action of both compounds...
  29. Daneshvar N, Ayazloo M, Khataee A, Pourhassan M. Biological decolorization of dye solution containing Malachite Green by microalgae Cosmarium sp. Bioresour Technol. 2007;98:1176-82 pubmed
    ..The optimal kinetic parameters, nu(max) and K(m) are 7.63 mg dye g cell(-1)h(-1) and 164.57 ppm, respectively. All assays were conducted in triplicates...
  30. Westermeier R. Sensitive, quantitative, and fast modifications for Coomassie Blue staining of polyacrylamide gels. Proteomics. 2006;6 Suppl 2:61-4 pubmed
  31. Yang M, Fang J, Kuo T, Wang D, Huang Y, Liu L, et al. Production of antibodies for selective detection of malachite green and the related triphenylmethane dyes in fish and fishpond water. J Agric Food Chem. 2007;55:8851-6 pubmed
  32. Lin J, Chen Q, Tian H, Gao X, Yu M, Xu G, et al. Stain efficiency and MALDI-TOF MS compatibility of seven visible staining procedures. Anal Bioanal Chem. 2008;390:1765-73 pubmed publisher
    ..The implications of these results for the selection of a convenient stain are discussed according to specific objectives as well as practical aspects...
  33. Diaz Hernandez M, Diez Zaera M, Sánchez Nogueiro J, Gomez Villafuertes R, Canals J, Alberch J, et al. Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration. FASEB J. 2009;23:1893-906 pubmed publisher
    ..These in vivo data strongly suggest that altered P2X7-receptor level and function contribute to HD pathogenesis and highlight the therapeutic potential of P2X7 receptor antagonists...
  34. Jang G, Park I, Lee S, Huh T, Lee Y. Malachite green induces cardiovascular defects in developing zebrafish (Danio rerio) embryos by blocking VEGFR-2 signaling. Biochem Biophys Res Commun. 2009;382:486-91 pubmed publisher
    ..It suggests that MG may be an environmental toxic agent with the potential to induce embryonic cardiovascular defects in vertebrates...
  35. Li L, Hong Q, Yan X, Fang G, Ali S, Li S. Isolation of a malachite green-degrading Pseudomonas sp. MDB-1 strain and cloning of the tmr2 gene. Biodegradation. 2009;20:769-76 pubmed publisher
    ..coli. These results highlight the potential of this bacterium for the bioremediation of aquatic environments contaminated by malachite green...
  36. Hameed B, Lee T. Degradation of malachite green in aqueous solution by Fenton process. J Hazard Mater. 2009;164:468-72 pubmed publisher
    ..50mM and initial ferrous concentration=0.10mM for initial MG concentration of 20mg/L at 30 degrees C. Under optimal conditions, 99.25% degradation efficiency of dye in aqueous solution was achieved after 60 min of reaction...
  37. Schuetze A, Heberer T, Juergensen S. Occurrence of residues of the veterinary drug malachite green in eels caught downstream from municipal sewage treatment plants. Chemosphere. 2008;72:1664-70 pubmed publisher
    ..According to European Union law, zero tolerance applies to all residues of MG and LMG found in food for human consumption as MG is not registered for use as veterinary drug...
  38. Farah M, Maia M, Rodrigues E. Dyes in ocular surgery: principles for use in chromovitrectomy. Am J Ophthalmol. 2009;148:332-40 pubmed publisher
    ..To present the current state-of-the-art information regarding the properties, indications, surgical techniques, and toxic effects of current and past applications of vital dyes in chromovitrectomy...
  39. Peng W, Cotrina M, Han X, Yu H, Bekar L, Blum L, et al. Systemic administration of an antagonist of the ATP-sensitive receptor P2X7 improves recovery after spinal cord injury. Proc Natl Acad Sci U S A. 2009;106:12489-93 pubmed publisher
    ..1), which crosses the blood-brain barrier. Systemic administration of BBG may thus comprise a readily feasible approach by which to treat traumatic SCI in humans...
  40. Pink M, Verma N, Rettenmeier A, Schmitz Spanke S. CBB staining protocol with higher sensitivity and mass spectrometric compatibility. Electrophoresis. 2010;31:593-8 pubmed publisher
    ..The modified procedure takes less time to carry out. Moreover, this practice is more sensitive and resolves more protein spots than most protocols reported to date and is compatible with subsequent mass spectrometric analysis...
  41. Beenen E, de Roy van Zuidewijn D. Patients blue on patent blue: an adverse reaction during four sentinel node procedures. Surg Oncol. 2005;14:151-4 pubmed
    ..We present four cases of an adverse reaction to patent blue V, one of which was an anaphylactic shock. The adverse reactions to patent blue and isosulphan blue as found in the literature are discussed and an alternative is suggested...
  42. Daneshvar N, Khataee A, Rasoulifard M, Pourhassan M. Biodegradation of dye solution containing Malachite Green: optimization of effective parameters using Taguchi method. J Hazard Mater. 2007;143:214-9 pubmed
    ..5h. The stability and efficiency of Chlorella sp. in long-term repetitive operations were also examined...
  43. Morales M, Freire V, Asumendi A, Araiz J, Herrera I, Castiella G, et al. Comparative effects of six intraocular vital dyes on retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2010;51:6018-29 pubmed publisher
    ..To evaluate and compare the effects of the following dyes on human pigmented epithelial cells: indocyanine green (ICG), infracyanine green (IfCG), trypan blue (TB), bromophenol blue (BrB), patent blue (PB), and Brilliant Blue G (BBG)...
  44. Hojo T, Nagao T, Kikuyama M, Akashi S, Kinoshita T. Evaluation of sentinel node biopsy by combined fluorescent and dye method and lymph flow for breast cancer. Breast. 2010;19:210-3 pubmed publisher
    ..We compared the combination of radioisotope or dye with a fluorescence compound to analyze lymph flow to identify targets for SNB...
  45. Gerlach N, Ghaeminia H, Bronkhorst E, Bergé S, Meijer G, Maal T. Accuracy of assessing the mandibular canal on cone-beam computed tomography: a validation study. J Oral Maxillofac Surg. 2014;72:666-71 pubmed publisher
    ..To establish the accuracy of cone-beam computed tomographic (CBCT) views in determining the position and diameter of the mandibular canal...
  46. Howard J, Moo V, Sivalingam P. Anaphylaxis and other adverse reactions to blue dyes: a case series. Anaesth Intensive Care. 2011;39:287-92 pubmed
    ..We also recommend high vigilance for possible allergic reactions when patent blue dyes are used for sentinel lymph node mapping, because the presentations may be atypical and the reduced pulse oximetry readings may be a distraction. ..
  47. Masin J, Fiser R, Linhartova I, Osicka R, Bumba L, Hewlett E, et al. Differences in purinergic amplification of osmotic cell lysis by the pore-forming RTX toxins Bordetella pertussis CyaA and Actinobacillus pleuropneumoniae ApxIA: the role of pore size. Infect Immun. 2013;81:4571-82 pubmed publisher
    ..These results point to a pore size threshold of purinergic amplification involvement in cell permeabilization by pore-forming RTX toxins. ..
  48. Guinement L, Marchesi V, Veres A, Lacornerie T, Buchheit I, Peiffert D. [Development of external quality control protocol for CyberKnife beams dosimetry: preliminary tests multicentre]. Cancer Radiother. 2013;17:288-96 pubmed publisher
    ..To develop an external quality control procedure for CyberKnife(®) beams. This work conducted in Nancy, has included a test protocol initially drawn by the medical physicist of Nancy and Lille in collaboration with Equal-Estro Laboratory...
  49. Kannan C, Muthuraja K, Devi M. Hazardous dyes removal from aqueous solution over mesoporous aluminophosphate with textural porosity by adsorption. J Hazard Mater. 2013;244-245:10-20 pubmed publisher
  50. Dong J, Peng Y, Gao N, Bai J, Ning B, Liu M, et al. A novel polymerization of ultrathin sensitive imprinted film on surface plasmon resonance sensor. Analyst. 2012;137:4571-6 pubmed publisher
    ..The results suggest that the ultrathin MIP film prepared using the new method in this study is suitable to serve as the recognition element of the SPR sensor...
  51. Prather B, Ethen C, Machacek M, Wu Z. Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays. Anal Biochem. 2012;423:86-92 pubmed publisher
    ..The activities obtained with the method were also validated by performing simultaneous radioisotope assays. Finally, the removal of PAP product inhibition by gPAPP was clearly demonstrated in radioisotope assays...
  52. Carlsson N, Kitts C, Akerman B. Spectroscopic characterization of Coomassie blue and its binding to amyloid fibrils. Anal Biochem. 2012;420:33-40 pubmed publisher
    ..Finally, linear dichroism was used to show that the fibril-bound CB is oriented preferentially parallel to the insulin amyloid fibril axis...
  53. Conner F, Vandewalle K, Bartoloni J. Degree of microleakage of a self-etch sealant. Gen Dent. 2011;59:224-8 pubmed
    ..The self-etch sealant had significantly more microleakage than the traditional sealant or the self-etch sealant with acid-etching of the enamel...