glutaral

Summary

Summary: One of the protein CROSS-LINKING REAGENTS that is used as a disinfectant for sterilization of heat-sensitive equipment and as a laboratory reagent, especially as a fixative.

Top Publications

  1. Kolker J, Vargas M, Armstrong S, Dawson D. Effect of desensitizing agents on dentin permeability and dentin tubule occlusion. J Adhes Dent. 2002;4:211-21 pubmed
    ..The aim of this study was to evaluate: 1) the effect of five dentin desensitizing agents (DDAs) on permeability using hydraulic conductance, and 2) morphological tubule changes with scanning electron microscopy (SEM)...
  2. Kampf G, Bloss R, Martiny H. Surface fixation of dried blood by glutaraldehyde and peracetic acid. J Hosp Infect. 2004;57:139-43 pubmed
    ..3%). Our findings underline the potential for blood fixation, not only by glutaraldehyde, but also by peracetic acid, and support the evidence that effective cleaning should precede the chemical disinfection...
  3. Lai J. Biocompatibility of chemically cross-linked gelatin hydrogels for ophthalmic use. J Mater Sci Mater Med. 2010;21:1899-911 pubmed publisher
    ..In comparison to GTA treatment, the EDC cross-linking is more suitable for preparation of chemically modified gelatin hydrogels for ophthalmic use...
  4. Buergers R, Rosentritt M, Schneider Brachert W, Behr M, Handel G, Hahnel S. Efficacy of denture disinfection methods in controlling Candida albicans colonization in vitro. Acta Odontol Scand. 2008;66:174-80 pubmed publisher
    ..The aim of this study was to rank 10 denture disinfection methods according to their efficacy in reducing Candida albicans (C. albicans) colonization on soft denture relining material...
  5. Nahalka J, Vikartovská A, Hrabarova E. A crosslinked inclusion body process for sialic acid synthesis. J Biotechnol. 2008;134:146-53 pubmed publisher
    ..The required substrate, N-acetyl-D-mannosamine, was obtained by partially improved alkaline epimerization...
  6. Lu P, Lai J, Ma D, Hsiue G. Carbodiimide cross-linked hyaluronic acid hydrogels as cell sheet delivery vehicles: characterization and interaction with corneal endothelial cells. J Biomater Sci Polym Ed. 2008;19:1-18 pubmed publisher
  7. Chiu H, Lin T, Wang J. Identification and characterization of an organic solvent tolerance gene in Helicobacter pylori. Helicobacter. 2007;12:74-81 pubmed
    ..However, some chemical-solvent-tolerant bacteria may survive after incomplete endoscopic disinfection. The goal of this study was to identify glutaraldehyde resistance-related genes in Helicobacter pylori...
  8. Qin C, Xu J, Zhang Y. Spectroscopic investigation of the function of aqueous 2-hydroxyethylmethacrylate/glutaraldehyde solution as a dentin desensitizer. Eur J Oral Sci. 2006;114:354-9 pubmed
    ..The function of Gluma as a desensitizer to block dentinal tubules occurs via these two reactions...
  9. Bisset L, Cossart Y, Selby W, West R, Catterson D, O Hara K, et al. A prospective study of the efficacy of routine decontamination for gastrointestinal endoscopes and the risk factors for failure. Am J Infect Control. 2006;34:274-80 pubmed
    ..Patient-ready endoscopes were monitored over an 80-week period to determine the efficacy of decontamination procedures in a busy endoscopy center. Decontamination failure was related to patient and procedural parameters...

More Information

Publications62

  1. Chen J, Zhang J, Han B, Li Z, Li J, Feng X. Synthesis of cross-linked enzyme aggregates (CLEAs) in CO2-expanded micellar solutions. Colloids Surf B Biointerfaces. 2006;48:72-6 pubmed
    ..This method has some advantages in applications and can be easily applied to the synthesis of other cross-linked enzyme aggregates...
  2. Duran I, Sengun A. The long-term effectiveness of five current desensitizing products on cervical dentine sensitivity. J Oral Rehabil. 2004;31:351-6 pubmed
  3. Gupta K, Jabrail F. Glutaraldehyde and glyoxal cross-linked chitosan microspheres for controlled delivery of centchroman. Carbohydr Res. 2006;341:744-56 pubmed
    ..The linear fractional release of centchroman with the square root of time indicated a Fickian behavior of centchroman, and the microspheres also showed zero-order release kinetics for centchroman...
  4. Nurnberg M, Schulz H, Ruden H, Vogt K. Do conventional cleaning and disinfection techniques avoid the risk of endoscopic Helicobacter pylori transmission?. Endoscopy. 2003;35:295-9 pubmed
    ..pylori transmission...
  5. Ishihata H, Kanehira M, Nagai T, Finger W, Shimauchi H, Komatsu M. Effect of desensitizing agents on dentin permeability. Am J Dent. 2009;22:143-6 pubmed
    ..The tested hypothesis was that the products, in spite of different chemical mechanisms were not different at reducing or eliminating flow through dentin discs...
  6. Howie R, Alfa M, Coombs K. Survival of enveloped and non-enveloped viruses on surfaces compared with other micro-organisms and impact of suboptimal disinfectant exposure. J Hosp Infect. 2008;69:368-76 pubmed publisher
    ..chelonae. Breakthrough survival was detected at 0.1% glutaraldehyde and 0.05% AHP for all organisms tested. Our data emphasise the need for effective cleaning and disinfection in nosocomial settings to prevent pathogen transmission...
  7. Spoerl E, Wollensak G, Reber F, Pillunat L. Cross-linking of human amniotic membrane by glutaraldehyde. Ophthalmic Res. 2004;36:71-7 pubmed
    ..However, in some diseases the transplant usually dissolves rather quickly and early detachment may occur. Therefore, we tried to stabilize the amniotic transplant by applying glutaraldehyde for collagen cross-linking of the membrane...
  8. Duran I, Sengun A, Yildirim T, Ozturk B. In vitro dentine permeability evaluation of HEMA-based (desensitizing) products using split-chamber model following in vivo application in the dog. J Oral Rehabil. 2005;32:34-8 pubmed
    ..The Gluma Desensitizing agent provide the more lasting tubule-occluding effect than the other material tested in this model...
  9. Bordas J, Marcos Maeso M, Perez M, Llach J, Gines A, Pique J. GI flexible endoscope disinfection: "in use" test comparative study. Hepatogastroenterology. 2005;52:800-7 pubmed
    ..The "in use" method is adequate for control and for establishing comparisons between different disinfectants...
  10. Vujcić Z, Milovanović A, Bozić N, Dojnov B, Vujcic M, Andjelković U, et al. Immobilization of cell wall invertase modified with glutaraldehyde for continuous production of invert sugar. J Agric Food Chem. 2010;58:11896-900 pubmed publisher
    ..9, and 45 °C. A 1 month productivity of 3844 kg of inverted sugar/kg of the immobilisate was obtained...
  11. Gao J, Li Z, Russell T, Li Z. Antibody affinity purification using metallic nickel particles. J Chromatogr B Analyt Technol Biomed Life Sci. 2012;895-896:89-93 pubmed publisher
    ..Methods proposed and tested in this study can be easily modified for small and medium scale antibody purification in lab and pre-clinical research...
  12. Akturk O, Tezcaner A, Bilgili H, Deveci M, Gecit M, Keskin D. Evaluation of sericin/collagen membranes as prospective wound dressing biomaterial. J Biosci Bioeng. 2011;112:279-88 pubmed publisher
    ..Overall results suggest that sericin/collagen membranes would be favorable as wound dressing material when sericin ratio is less than or equal to the collagen component...
  13. Zhou Y, Jia Y, Buehler P, Chen G, Cabrales P, Palmer A. Synthesis, biophysical properties, and oxygenation potential of variable molecular weight glutaraldehyde-polymerized bovine hemoglobins with low and high oxygen affinity. Biotechnol Prog. 2011;27:1172-84 pubmed publisher
    ..We suggest that the information gained from this study can be used to guide the design of the next generation of hemoglobin-based oxygen carriers (HBOCs) for use in tissue engineering and transfusion medicine applications...
  14. Pereira S, Oliveira R, Coelho S, Musso C, Soares A, Domingues I, et al. From sub cellular to community level: toxicity of glutaraldehyde to several aquatic organisms. Sci Total Environ. 2014;470-471:147-58 pubmed publisher
    ..6 mg/l, mesocosm and chronic toxicity tests seem to be the next step in direction of more realistic scenarios of GA risk assessment in aquatic ecosystems...
  15. Suzuki S, Ikada Y. Sealing effects of cross-linked gelatin. J Biomater Appl. 2013;27:801-10 pubmed publisher
    ..The gelatin gel was found to be also effective as barrier to prevent adhesion in a rat cecum abrasion model...
  16. Kulkarni R, Mutalik S, Mangond B, Nayak U. Novel interpenetrated polymer network microbeads of natural polysaccharides for modified release of water soluble drug: in-vitro and in-vivo evaluation. J Pharm Pharmacol. 2012;64:530-40 pubmed publisher
    ..The objective of this work was to prepare novel interpenetrating polymer network (IPN) microbeads of tamarind seed polysaccharide and sodium alginate for controlled release of the water soluble drug, diltiazem hydrochloride...
  17. Knox Cartwright N, Tyrer J, Marshall J. In vitro quantification of the stiffening effect of corneal cross-linking in the human cornea using radial shearing speckle pattern interferometry. J Refract Surg. 2012;28:503-8 pubmed
    ..To quantify the magnitude of the stiffening effect of corneal cross-linking (CXL) by studying intact human corneas exposed to physiological pressure transients...
  18. Schneider J, Ochs M. Alterations of mouse lung tissue dimensions during processing for morphometry: a comparison of methods. Am J Physiol Lung Cell Mol Physiol. 2014;306:L341-50 pubmed publisher
  19. Wang Q, Luo B, Yang X, Wang K, Liu L, Du S, et al. Elucidation of the effect of aptamer immobilization strategies on the interaction between cell and its aptamer using atomic force spectroscopy. J Mol Recognit. 2016;29:151-8 pubmed publisher
    ..Presumably, these factors may affect the accessibility of the aptamer toward its target cell. These results may provide valuable information for aptamer sensor platforms including ultrasensitive biosensor design...
  20. Xu C, Wang Y. Cross-linked demineralized dentin maintains its mechanical stability when challenged by bacterial collagenase. J Biomed Mater Res B Appl Biomater. 2011;96:242-8 pubmed publisher
    ..These results suggested that improving the degree of crosslinking in dentin collagen could be one method to inhibit its biodegradation and further to increase the durability of dental restorations...
  21. Tandjaoui N, Abouseoud M, Couvert A, Amrane A, Tassist A. A new combined green method for 2-Chlorophenol removal using cross-linked Brassica rapa peroxidase in silicone oil. Chemosphere. 2016;148:55-60 pubmed publisher
    ..66 UI mL(-1) BRP-CLEAs. The reusability of BRP-CLEAs in silicone oil was assessed, showing promising results since 59% of their initial efficiency remained after three batches. ..
  22. Ferreira T, Barbosa T, Teixeira F, Ferreira E, Duarte R, Domingues R, et al. Effect of hospital disinfectants on spores of clinical Brazilian Clostridium difficile strains. Anaerobe. 2013;22:121-2 pubmed publisher
    ..Our results showed that CloroRio(®) and Cidex Opa(®) were the most efficient agents for eliminating spores of C difficile. ..
  23. Elloumi Mseddi J, Jellali K, Aifa S. In vitro activation and inhibition of recombinant EGFR tyrosine kinase expressed in Escherichia coli. ScientificWorldJournal. 2013;2013:807284 pubmed publisher
    ..The activity assay has revealed the autophosphorylation of EGFR proteins which was decreased in the presence of genistein. Our system could facilitate the screening of EGFR inhibitors without the need of adding an exogenous substrate. ..
  24. Shalan H, Awad S, El Fallal A. Influence of pulpotomy medicaments on the ultrastructure and shear bond strength of a self-etch adhesive to primary tooth dentin. Quintessence Int. 2012;43:517-23 pubmed
    ..To compare the effect of the pulpotomy medicaments glutaraldehyde, ferric sulfate, and formocresol on the structure and shear bond strength of a self-etch adhesive to the dentin of primary teeth...
  25. Harris D, Tal O, Jallet D, Wilson A, Kirilovsky D, Adir N. Orange carotenoid protein burrows into the phycobilisome to provide photoprotection. Proc Natl Acad Sci U S A. 2016;113:E1655-62 pubmed publisher
    ..Penetration of the N-terminal domain can bring the OCP carotenoid to within 5-10 Ã… of core chromophores; however, alteration of the core structure may be the actual source of energy dissipation. ..
  26. Wang W, Lin J, Tsai C, Chuang H, Ho C, Yao C, et al. Biodegradable glutaraldehyde-crosslinked casein conduit promotes regeneration after peripheral nerve injury in adult rats. Macromol Biosci. 2011;11:914-26 pubmed publisher
    ..Therefore, we conclude that the GCC can offer great nerve regeneration characteristics and can be a promising material for the successful repair of peripheral nerve defects...
  27. Antonova N, Riha P, Ivanov I, Gluhcheva Y. Experimental evaluation of mechanical and electrical properties of RBC suspensions in Dextran and PEG under flow II. Role of RBC deformability and morphology. Clin Hemorheol Microcirc. 2011;49:441-50 pubmed publisher
  28. Sabagh B, Souto A, Reis L, Silva S, Pereira D, Neves M, et al. Comparative study with two different enrichments in the culture media used in the disinfectant efficacy assay. J Microbiol Methods. 2012;88:255-62 pubmed publisher
    ..These results suggest that low-cost enrichment FBSG may be used as a potential substitute of ADC for composition of media for mycobacterial growth, including in disinfectant tests...
  29. Braile M, Carnevalli N, Goissis G, Ramirez V, Braile D. In vitro properties and performance of glutaraldehyde-crosslinked bovine pericardial bioprostheses treated with glutamic acid. Artif Organs. 2011;35:497-501 pubmed publisher
    ..These results indicate that the processing of BP described in this work may be of potential use in the manufacture of HVBs...
  30. Serwer P, Wright E. Agarose gel electrophoresis reveals structural fluidity of a phage T3 DNA packaging intermediate. Electrophoresis. 2012;33:352-65 pubmed publisher
    ..The analysis of ipDNA-capsids, rather than intermediates with uncleaved DNA, provides a simplifying strategy for a complete biochemical analysis of in vivo DNA packaging...
  31. Li Z, Gu L. Fabrication of self-assembled (-)-epigallocatechin gallate (EGCG) ovalbumin-dextran conjugate nanoparticles and their transport across monolayers of human intestinal epithelial Caco-2 cells. J Agric Food Chem. 2014;62:1301-9 pubmed publisher
    ..EGCG O-D conjugate nanoparticles significantly enhanced the apparent permeability coefficient (Papp) of EGCG on Caco-2 monolayers compared with EGCG solution, suggesting that these nanoparticles may improve the absorption of EGCG. ..
  32. Jones W, Sutton M, McKittrick L, Stewart P. Chemical and antimicrobial treatments change the viscoelastic properties of bacterial biofilms. Biofouling. 2011;27:207-15 pubmed publisher
    ..Understanding biofilm rheology and how it is affected by chemical treatment could lead to improvements in biofilm control...
  33. Sakamoto S, Nagamitsu R, Matsuura Y, Tsuneura Y, Kurose H, Tanaka H, et al. A new approach of indirect enzyme-linked immunosorbent assay for determination of D-glutamic acid through in situ conjugation. J Immunoassay Immunochem. 2016;37:296-306 pubmed publisher
  34. Lee K, Choi S, Yang C, Wu H, Yu J. Autofluorescence generation and elimination: a lesson from glutaraldehyde. Chem Commun (Camb). 2013;49:3028-30 pubmed publisher
    ..A model indicated that ethylenediamine and a secondary amine in the molecule were key components for the formation of emissive species. The mechanism enables us to control the generation and elimination of autofluorescence...
  35. Zhu C, Xu Y, Xu K. [The effect of disinfectant soaking on dental gypsum model size]. Shanghai Kou Qiang Yi Xue. 2012;21:656-8 pubmed
    ..To study the influence of disinfectant soaking on the dimensional stability of three kinds of dental gypsum model...
  36. Sailer I, Oendra A, Stawarczyk B, Hammerle C. The effects of desensitizing resin, resin sealing, and provisional cement on the bond strength of dentin luted with self-adhesive and conventional resincements. J Prosthet Dent. 2012;107:252-60 pubmed publisher
    ..Little is known about the effect of dentin pretreatment on the bond quality of self-adhesive resin cements...
  37. Wang Z, Dong J, Li D. Conformational changes in photosynthetic pigment proteins on thylakoid membranes can lead to fast non-photochemical quenching in cyanobacteria. Sci China Life Sci. 2012;55:726-34 pubmed publisher
    ..42% of the total NPQ. We hypothesize therefore, that NPQf induced by PPPTM conformation is an important adaptation mechanism for Microcystis blooms under high-intensity light during summer and autumn...
  38. Lyubin E, Khokhlova M, Skryabina M, Fedyanin A. Cellular viscoelasticity probed by active rheology in optical tweezers. J Biomed Opt. 2012;17:101510 pubmed publisher
  39. Spotnitz W, Burks S. Hemostats, sealants, and adhesives III: a new update as well as cost and regulatory considerations for components of the surgical toolbox. Transfusion. 2012;52:2243-55 pubmed publisher
    ..The system of definitions will also be used to clarify key strategies in the current health care environment for reducing costs and for increasing understanding of Food and Drug Administration regulatory decisions for these materials...
  40. Vasconcelos L, Consani R, Mesquita M, Sinhoreti M. Effect of chemical and microwave disinfection on the surface microhardness of acrylic resin denture teeth. J Prosthodont. 2013;22:298-303 pubmed publisher
  41. Sethna G, Prabhuji M, Karthikeyan B. Comparison of two different forms of varnishes in the treatment of dentine hypersensitivity: a subject-blind randomised clinical study. Oral Health Prev Dent. 2011;9:143-50 pubmed
    ..The purpose of this study was to compare the efficacy of two different desensitising agents, Cervitec varnish and Gluma varnish...
  42. Cubillos Rojas M, Schneider T, Sánchez Tena S, Bartrons R, Ventura F, Rosa J. Tris-acetate polyacrylamide gradient gel electrophoresis for the analysis of protein oligomerization. Anal Bioanal Chem. 2016;408:1715-9 pubmed publisher
    ..This approach can be easily extrapolated to the study of other oligomers. All of these features make this method a highly useful tool for the analysis of protein oligomerization. ..
  43. Puga A, Lima A, Mano J, Concheiro A, Alvarez Lorenzo C. Pectin-coated chitosan microgels crosslinked on superhydrophobic surfaces for 5-fluorouracil encapsulation. Carbohydr Polym. 2013;98:331-40 pubmed publisher
    ..Growth inhibition of cancer cells by 5-FU was greater when incorporated to chitosan microgels; these being potentially useful for treatment of skin and colorectal tumors...
  44. Tomaiuolo G, Guido S. Start-up shape dynamics of red blood cells in microcapillary flow. Microvasc Res. 2011;82:35-41 pubmed publisher
    ..Our results provide a novel microfluidics methodology to measure the RBC characteristic time which is a potential diagnostic parameter of altered cell deformability...
  45. André C, Herlem G, Gharbi T, Guillaume Y. A new arginase enzymatic reactor: development and application for the research of plant-derived inhibitors. J Pharm Biomed Anal. 2011;55:48-53 pubmed publisher
    ..Our results confirmed the direct effect of some plant extracts on the arginase activity and their interest in therapies for treating several NO-dependent smooth disorders...
  46. Shankar S, Kumar S, Mulimani V. Calcium alginate entrapped preparation of ?-galactosidase: its stability and application in hydrolysis of soymilk galactooligosaccharides. J Ind Microbiol Biotechnol. 2011;38:1399-405 pubmed publisher
    ..The entrapped crosslinked concanavalin A-?-galactosidase complex retained 95% activity after eight cycles of use...
  47. Knezević Jugović Z, Bezbradica D, Mijin D, Antov M. The immobilization of enzyme on Eupergit® supports by covalent attachment. Methods Mol Biol. 2011;679:99-111 pubmed publisher
  48. An Y, Cao Y, Xu Y. Purification and characterization of the plastid-localized NAD-dependent malate dehydrogenase from Arabidopsis thaliana. Biotechnol Appl Biochem. 2016;63:490-6 pubmed publisher
    ..Moreover, we obtained crystals for this enzyme, which laid the groundwork for further analysis of the enzymatic mechanism from structural stand point. ..
  49. Rakhshaee R, PANAHANDEH M. Stabilization of a magnetic nano-adsorbent by extracted pectin to remove methylene blue from aqueous solution: a comparative studying between two kinds of cross-linked pectin. J Hazard Mater. 2011;189:158-66 pubmed publisher
    ..16.23, 19.76 and 23.04 (× 10(-3)g/mg min) by FN-PAA. The adsorption force arrangement of MB by these nano-biosorbents regarding their activation energy was obtained as: FN-PAA>FN-PAG>FN-PA...
  50. Temoçin Z. Covalent immobilization of Candida rugosa lipase on aldehyde functionalized hydrophobic support and the application for synthesis of oleic acid ester. J Biomater Sci Polym Ed. 2013;24:1618-35 pubmed publisher
    ..In addition, after five reuses, the esterification percent yield of the immobilized CRL slightly decreased from 29 to 27%. ..
  51. Wang X, Lin H, Wang Q, Gu Y. Specific antitumor immunity induced by cross-linking complex heat shock protein 72 and alpha-fetoprotein. Cancer Biother Radiopharm. 2012;27:189-97 pubmed publisher
    ..Priming mice with the reconstructed vaccine, we elicited robust strong protective immunity. Our study suggests that a tumor vaccine by cross-linking tumor antigen and HSP72 is a promising approach for cancer therapy...
  52. Guentsch A, Seidler K, Nietzsche S, Hefti A, Preshaw P, Watts D, et al. Biomimetic mineralization: long-term observations in patients with dentin sensitivity. Dent Mater. 2012;28:457-64 pubmed publisher
    ..This study evaluated the effectiveness on DS of a biomimetic mineralization system (BIMIN) in comparison to the current standard treatment (Gluma(®) Desensitizer, Gluma)...
  53. Florin W, Mandel L. Foreign body reaction to facial dermal fillers: case report. J Oral Maxillofac Surg. 2012;70:2352-5 pubmed publisher
    ..5 cm in height. Posteriorly, palpation of the left parotid gland revealed the gland to be painless, normal in tone, and not swollen. No swelling or discomfort was evident on the right side. No trismus was present...