octoxynol

Summary

Summary: Nonionic surfactant mixtures varying in the number of repeating ethoxy (oxy-1,2-ethanediyl) groups. They are used as detergents, emulsifiers, wetting agents, defoaming agents, etc. Octoxynol-9, the compound with 9 repeating ethoxy groups, is a spermatocide.

Top Publications

  1. Zou Y, Zhang Y. Mechanical evaluation of decellularized porcine thoracic aorta. J Surg Res. 2012;175:359-68 pubmed publisher
    ..In the present study, the effects of different decellularization protocols on the (passive) mechanical properties of the resulted porcine aortic ECM were evaluated...
  2. Nakai M, Ito J, Sato K, Noguchi J, Kaneko H, Kashiwazaki N, et al. Pre-treatment of sperm reduces success of ICSI in the pig. Reproduction. 2011;142:285-93 pubmed publisher
  3. van de Ven A, Adler Storthz K, Richards Kortum R. Delivery of optical contrast agents using Triton-X100, part 1: reversible permeabilization of live cells for intracellular labeling. J Biomed Opt. 2009;14:021012 pubmed publisher
    ..We conclude that Triton-X100 is a promising permeabilization agent for efficient and reproducible delivery of optical contrast agents into live mammalian cells...
  4. Morbeck D, Khan Z, Barnidge D, Walker D. Washing mineral oil reduces contaminants and embryotoxicity. Fertil Steril. 2010;94:2747-52 pubmed publisher
    ..To determine if washing improves the quality of mineral oil used for embryo culture...
  5. Mrówczyńska L, Salzer U, Iglic A, Hagerstrand H. Curvature factor and membrane solubilization, with particular reference to membrane rafts. Cell Biol Int. 2011;35:991-5 pubmed publisher
    ..The stomatocytogenic, Triton X-100, cannot effectively solubilize membrane components, especially with regard to the outward membrane curvature...
  6. Khan Z, Wolff H, Fredrickson J, Walker D, Daftary G, Morbeck D. Mouse strain and quality control testing: improved sensitivity of the mouse embryo assay with embryos from outbred mice. Fertil Steril. 2013;99:847-854.e2 pubmed publisher
    ..To determine the relative sensitivities of embryos from different strains of mice to in vitro stress...
  7. Renzoni A, Barras C, Francois P, Charbonnier Y, Huggler E, Garzoni C, et al. Transcriptomic and functional analysis of an autolysis-deficient, teicoplanin-resistant derivative of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2006;50:3048-61 pubmed
    ..Instead, our analysis points to alternate regulatory mechanisms that impact autolysis effectors which may include changes in posttranscriptional processing or export...
  8. Nakai M, Kashiwazaki N, Takizawa A, Maedomari N, Ozawa M, Noguchi J, et al. Morphologic changes in boar sperm nuclei with reduced disulfide bonds in electrostimulated porcine oocytes. Reproduction. 2006;131:603-11 pubmed
    ..However, pronucleus formation and development to the blastocyst stage in vitro were not improved by sperm treatment. Thus, electrical stimulation of injected oocytes enhances in vitro development to the blastocyst stage in pigs...
  9. Geertsma E, Nik Mahmood N, Schuurman Wolters G, Poolman B. Membrane reconstitution of ABC transporters and assays of translocator function. Nat Protoc. 2008;3:256-66 pubmed publisher
    ..The full protocol can be completed within 4-5 d...

More Information

Publications62

  1. Manna A, Ingavale S, Maloney M, van Wamel W, Cheung A. Identification of sarV (SA2062), a new transcriptional regulator, is repressed by SarA and MgrA (SA0641) and involved in the regulation of autolysis in Staphylococcus aureus. J Bacteriol. 2004;186:5267-80 pubmed publisher
    ..aureus. We propose that sarV may be part of the common pathway by which mgrA and sarA gene products control autolysis in S. aureus...
  2. Ajduk A, Yamauchi Y, Ward M. Sperm chromatin remodeling after intracytoplasmic sperm injection differs from that of in vitro fertilization. Biol Reprod. 2006;75:442-51 pubmed
    ..Our data have significance for the refinement of the molecular and biologic mechanisms associated with ICSI for current and future applications...
  3. Chang Q, Gummadi S, Menon A. Chemical modification identifies two populations of glycerophospholipid flippase in rat liver ER. Biochemistry. 2004;43:10710-8 pubmed
    ..This observation holds considerable promise for future attempts to isolate the flippase via an affinity approach...
  4. Malinska K, Malinsky J, Opekarova M, Tanner W. Distribution of Can1p into stable domains reflects lateral protein segregation within the plasma membrane of living S. cerevisiae cells. J Cell Sci. 2004;117:6031-41 pubmed
    ..Finally, two other proteins were localized within the frame of the Can1p/Pma1p plasma-membrane partition. We show that Fur4p (another H+ symporter) and Sur7p (a protein of unknown function) occupy the Can1p subdomain...
  5. Wootton M, Bennett P, Macgowan A, Walsh T. Reduced expression of the atl autolysin gene and susceptibility to autolysis in clinical heterogeneous glycopeptide-intermediate Staphylococcus aureus (hGISA) and GISA strains. J Antimicrob Chemother. 2005;56:944-7 pubmed
    ..To assess a link between resistance to Triton X-100 induced autolysis (TIA) and lowered atl expression in a collection of clinical glycopeptide-intermediate Staphylococcus aureus (GISA) and heterogeneous GISA (hGISA)...
  6. Kiley P, Zhao X, Vaughn M, Baldo M, Bruce B, Zhang S. Self-assembling peptide detergents stabilize isolated photosystem I on a dry surface for an extended time. PLoS Biol. 2005;3:e230 pubmed
    ..These observations suggest that the peptide detergents may effectively stabilize membrane proteins in the solid-state. These designed peptide detergents may facilitate the study of diverse types of membrane proteins...
  7. Morandat S, El Kirat K. Membrane resistance to Triton X-100 explored by real-time atomic force microscopy. Langmuir. 2006;22:5786-91 pubmed
    ..We are convinced that this approach will provide a key system to elucidate the physical mechanisms of membrane solubilization by nonionic detergents...
  8. Vehring S, Pakkiri L, Schröer A, Alder Baerens N, Herrmann A, Menon A, et al. Flip-flop of fluorescently labeled phospholipids in proteoliposomes reconstituted with Saccharomyces cerevisiae microsomal proteins. Eukaryot Cell. 2007;6:1625-34 pubmed
    ..Our work defines yeast as a promising model system for future attempts to identify the ER phospholipid flippase and to test and purify candidate flippases...
  9. Aboulwafa M, Saier M. Characterization of soluble enzyme II complexes of the Escherichia coli phosphotransferase system. J Bacteriol. 2004;186:8453-62 pubmed
    ..coli. Thus, both phosphoenolpyruvate-dependent phosphotransferase system enzymes exist in soluble and membrane-integrated forms that exhibit dissimilar physical and kinetic properties...
  10. Sawai H, Domae N. Differential roles for Bak in Triton X-100- and deoxycholate-induced apoptosis. Biochem Biophys Res Commun. 2009;378:529-33 pubmed publisher
  11. Loberto N, Prioni S, Bettiga A, Chigorno V, Prinetti A, Sonnino S. The membrane environment of endogenous cellular prion protein in primary rat cerebellar neurons. J Neurochem. 2005;95:771-83 pubmed
    ..Thus, prion protein plasma membrane environment in differentiated neurons resulted to be a complex entity, whose integrity requires a network of lipid-mediated non-covalent interactions...
  12. Van Horn C, Caviglia J, Li L, Wang S, Granger D, Coleman R. Characterization of recombinant long-chain rat acyl-CoA synthetase isoforms 3 and 6: identification of a novel variant of isoform 6. Biochemistry. 2005;44:1635-42 pubmed
    ..These data further document important differences in the closely related ACSL isoforms and show that amino acid changes near the consensus nucleotide binding site alter function in the two splice variants of ACSL6...
  13. Staneva G, Seigneuret M, Koumanov K, Trugnan G, Angelova M. Detergents induce raft-like domains budding and fission from giant unilamellar heterogeneous vesicles: a direct microscopy observation. Chem Phys Lipids. 2005;136:55-66 pubmed
    ..It is also suggested that the physico-chemical mechanisms involved in l(o) domain budding and fission might play a role in rafts-dependant endocytosis in cells...
  14. Dubrac S, Boneca I, Poupel O, Msadek T. New insights into the WalK/WalR (YycG/YycF) essential signal transduction pathway reveal a major role in controlling cell wall metabolism and biofilm formation in Staphylococcus aureus. J Bacteriol. 2007;189:8257-69 pubmed publisher
    ..Taken together, our results now define this signal transduction pathway as a master regulatory system for cell wall metabolism, which we have accordingly renamed WalK/WalR to reflect its true function...
  15. Hamada T, Miura Y, Ishii K, Araki S, Yoshikawa K, Vestergaard M, et al. Dynamic processes in endocytic transformation of a raft-exhibiting giant liposome. J Phys Chem B. 2007;111:10853-7 pubmed
    ..We discuss the mechanism of this difference in terms of the kinetic pathway of internalization by considering the line energy and bending energy of the membrane...
  16. Merino E, Rodrigues C, Viciosa M, Melo C, Sotomayor J, Dionísio M, et al. Phase transformations undergone by Triton X-100 probed by differential scanning calorimetry and dielectric relaxation spectroscopy. J Phys Chem B. 2011;115:12336-47 pubmed publisher
    ..This is compatible with the estimated low Avrami exponent (1.12 ? n ? 1.6), suggesting that relative short length scale motions govern the crystal growth in Triton X-100 coherent with the observation of a grainy crystallization by POM...
  17. Dong X, Meng Y, Feng X, Sun Y. A metal-chelate affinity reverse micellar system for protein extraction. Biotechnol Prog. 2010;26:150-8 pubmed publisher
  18. Browne G, Dickens M. Reversible translocation of ASK1 to a Triton-X100 insoluble cytoplasmic compartment during cardiac myocyte cell stress. J Recept Signal Transduct Res. 2011;31:408-15 pubmed publisher
    ..The structures to which ASK1 translocates in cardiac myocytes do not appear to correspond to the previously described ASK1 signalosome reported in other cell types...
  19. Neumeyer A, Bukowski M, Veith M, Lehr C, Daum N. Non-invasive determination of cellular oxygen consumption as novel cytotoxicity assay for nanomaterials. Nanotoxicology. 2014;8:50-60 pubmed publisher
    ..Thereby, the SensorDish® Reader allows a life documentation of the cellular behaviour and clarifies that size, time, concentration and surface modification of nanoparticles affect cellular viability...
  20. Wang H, Yang J, Lei S, Wang X. Comparing the effect of biosurfactant and chemical surfactant on bubble hydrodynamics in a flotation column. Water Sci Technol. 2013;68:783-90 pubmed publisher
    ..This will contribute to promoting the use of green environmentally friendly flotation agents in the separation industry. ..
  21. Shcherbakova O, Serebryanaya D, Postnikov A, Schroeter M, Zittrich S, Noegel A, et al. Kinase-related protein/telokin inhibits Ca2+-independent contraction in Triton-skinned guinea pig taenia coli. Biochem J. 2010;429:291-302 pubmed publisher
  22. Lundbaek J, Koeppe R, Andersen O. Amphiphile regulation of ion channel function by changes in the bilayer spring constant. Proc Natl Acad Sci U S A. 2010;107:15427-30 pubmed publisher
    ..The use of gA channels as molecular force probes provides a tool for quantitative, predictive studies of bilayer-mediated regulation of membrane protein function by amphiphiles...
  23. Woltjer R, Duerson K, Fullmer J, Mookherjee P, Ryan A, Montine T, et al. Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in Alzheimer disease. J Neuropathol Exp Neurol. 2010;69:667-76 pubmed publisher
    ..These findings lend further support to the idea that dysregulation of the glutamatergic system may play a significant role in AD pathogenesis...
  24. Iqbal T, Byrd Jacobs C. Rapid degeneration and regeneration of the zebrafish olfactory epithelium after triton X-100 application. Chem Senses. 2010;35:351-61 pubmed publisher
    ..Thus, chemical ablation causes temporary reduction with swift regeneration of the OE occurring within a week...
  25. Owsianiak M, Szulc A, Chrzanowski Ł, Cyplik P, Bogacki M, Olejnik Schmidt A, et al. Biodegradation and surfactant-mediated biodegradation of diesel fuel by 218 microbial consortia are not correlated to cell surface hydrophobicity. Appl Microbiol Biotechnol. 2009;84:545-53 pubmed publisher
    ..In contrary to what was previously reported for pure strains, cell surface hydrophobicity, as determined by MATH, is not a good descriptor of biodegrading potential for mixed cultures...
  26. Huang S, Xiao Q, Li R, Guan H, Liu J, Liu X, et al. A simple and sensitive method for L-cysteine detection based on the fluorescence intensity increment of quantum dots. Anal Chim Acta. 2009;645:73-8 pubmed publisher
    ..The proposed method possessed the advantages of simplicity, rapidity and sensitivity. Synthetic amino acid samples, medicine sample together with human urine samples were analyzed by the methodology and the results were satisfying...
  27. Cunningham R. Indirect immunofluorescent labeling of fixed cells. Methods Mol Biol. 2010;588:335-9 pubmed publisher
    ..Various staining protocols are provided. Routine cell surface and intracellular techniques as well as more advanced signal enhancement techniques are detailed...
  28. Richardson K, Xue Z, Huang Y, Seo Y, Lapitsky Y. Physicochemical and antibacterial properties of surfactant mixtures with quaternized chitosan microgels. Carbohydr Polym. 2013;93:709-17 pubmed publisher
    ..This suggests that surfactant-based products that use quaternized chitosan microgels as antibacterial agents should optimally be formulated using nonionic surfactants...
  29. Hu Z, Zhang X, Wu Z, Qi H, Wang Z. Export of intracellular Monascus pigments by two-stage microbial fermentation in nonionic surfactant micelle aqueous solution. J Biotechnol. 2012;162:202-9 pubmed publisher
  30. Guan Q, Noblitt S, Henry C. Electrophoretic separations in poly(dimethylsiloxane) microchips using mixtures of ionic, nonionic and zwitterionic surfactants. Electrophoresis. 2012;33:2875-83 pubmed publisher
    ..Finally, the detection of catecholamine release from PC12 cells by stimulation with 80 mM K(+) was performed to demonstrate the usefulness of mixed surfactant systems to provide resolution of biological compounds in complex samples...
  31. Kumar A, Tiwari S, Thavaselvam D, Sathyaseelan K, Prakash A, Barua A, et al. Optimization and efficient purification of recombinant Omp28 protein of Brucella melitensis using Triton X-100 and ?-mercaptoethanol. Protein Expr Purif. 2012;83:226-32 pubmed publisher
    ..8 and 9.37mg/g of wet weight of cells in pQE30UA and pET28a(+) vector respectively. Thus modified purification protocol yielded more than threefold increase of protein in pQE30UA as compared with purification by conventional methods...
  32. Novototskaya Vlasova K, Petrovskaya L, Yakimov S, Gilichinsky D. Cloning, purification, and characterization of a cold-adapted esterase produced by Psychrobacter cryohalolentis K5T from Siberian cryopeg. FEMS Microbiol Ecol. 2012;82:367-75 pubmed publisher
    ..Various organic solvents (ethanol, methanol and others) inhibited the enzyme. Most non-ionic detergents, such as Triton X-100 and Tween 20 increased the lipase activity while SDS completely inhibited it...
  33. Wichelecki D, McNew T, Aygun A, Torrey K, Stephenson L. Detection of liposome lysis utilizing an enzyme-substrate system. Appl Biochem Biotechnol. 2011;165:548-58 pubmed publisher
    ..This new protocol eliminates the complications of multiple reaction enzyme detection methods, along with the chance for false negatives and unreliable data seen when using fluorescent particles as reporters...
  34. Lima T, Procópio L, Brandão F, Carvalho A, Tótola M, Borges A. Simultaneous phenanthrene and cadmium removal from contaminated soil by a ligand/biosurfactant solution. Biodegradation. 2011;22:1007-15 pubmed publisher
    ..The results indicate that the use of a single washing agent, called surfactant-ligand, affords simultaneous removal of organic contaminants and heavy metals...
  35. Caparanga A, Basilia B, Dagbay K, Salvacion J. Factors affecting degradation of polyethylene terephthalate (PET) during pre-flotation conditioning. Waste Manag. 2009;29:2425-8 pubmed publisher
    ..Results show that in addition to water the presence of NaOH in the conditioning solution contributes to the further degradation of the polymer...
  36. Watanabe H, Suzuki H, Fukui Y. Fertilizability, developmental competence, and chromosomal integrity of oocytes microinjected with pre-treated spermatozoa in mice. Reproduction. 2010;139:513-21 pubmed publisher
    ..These results indicate that excessive sperm pre-treatment such as DTT for 60 min generates severe chromosome damage in injected oocytes, and that the damage decreases developmental competence to live fetuses but not to blastocysts...
  37. Zheng G, Selvam A, Wong J. Oil-in-water microemulsions enhance the biodegradation of DDT by Phanerochaete chrysosporium. Bioresour Technol. 2012;126:397-403 pubmed publisher
    ..chrysosporium; of these, the former is likely the most important and pre-requisite for the biodegradation of DDT by P. chrysosporium...
  38. Mukherjee D, May M, Khomami B. Detergent-protein interactions in aqueous buffer suspensions of Photosystem I (PS I). J Colloid Interface Sci. 2011;358:477-84 pubmed publisher
  39. Rosas J, Vicente F, Santos A, Romero A. Enhancing p-cresol extraction from soil. Chemosphere. 2011;84:260-4 pubmed publisher
    ..p-Cresol extraction efficiencies higher than 70% and 60% for Tween 80 and Citrate, respectively...
  40. Löving R, Wu S, Sjöberg M, Lindqvist B, Garoff H. Maturation cleavage of the murine leukemia virus Env precursor separates the transmembrane subunits to prime it for receptor triggering. Proc Natl Acad Sci U S A. 2012;109:7735-40 pubmed publisher
    ..The Env legs of this mutant were found to be separated, like in the mature Env. This shows that it is the TM leg separation, normally caused by R-peptide cleavage, that primes the Env for receptor triggering...
  41. Weyler C, Bureik M, Heinzle E. Selective oxidation of UDP-glucose to UDP-glucuronic acid using permeabilized Schizosaccharomyces pombe expressing human UDP-glucose 6-dehydrogenase. Biotechnol Lett. 2016;38:477-81 pubmed publisher
    ..With this reaction system 5 mM UDP-glucose were converted into 5 mM UDP-glucuronic acid within 3 h. Recombinant permeabilized cells of S. pombe can be used to synthesize UDP-glucuronic acid with 100 % yield and selectivity. ..
  42. Nagarnaik P, Boulanger B. Advanced oxidation of alkylphenol ethoxylates in aqueous systems. Chemosphere. 2011;85:854-60 pubmed publisher
  43. Sengottaiyan P, Ruiz Pavón L, Persson B. Functional expression, purification and reconstitution of the recombinant phosphate transporter Pho89 of Saccharomyces cerevisiae. FEBS J. 2013;280:965-75 pubmed publisher
    ..Moreover, its activity is sensitive to the Na(+) ionophore monensin. To our knowledge, this study represents the first report on the functional reconstitution of a Pi-coupled PiT family member...
  44. Ushimaru K, Sangiambut S, Thomson N, Sivaniah E, Tsuge T. New insights into activation and substrate recognition of polyhydroxyalkanoate synthase from Ralstonia eutropha. Appl Microbiol Biotechnol. 2013;97:1175-82 pubmed publisher
    ..These results suggest that the 3'-phosphate group of CoA plays a critical role in substrate recognition by PhaC(Re)...
  45. Stadler C, Skogs M, Brismar H, Uhlen M, Lundberg E. A single fixation protocol for proteome-wide immunofluorescence localization studies. J Proteomics. 2010;73:1067-78 pubmed publisher
  46. Pan T, Wang Z, Xu J, Wu Z, Qi H. Extractive fermentation in cloud point system for lipase production by Serratia marcescens ECU1010. Appl Microbiol Biotechnol. 2010;85:1789-96 pubmed publisher
    ..Thus, a concentration factor 4.2-fold and a purification factor 1.3-fold of the lipase have been achieved in the extractive fermentation process. This is the first report about extractive fermentation of proteins in cloud point system...
  47. Ma Y, Dai Z, Zha Z, Gao Y, Yue X. Selective antileukemia effect of stabilized nanohybrid vesicles based on cholesteryl succinyl silane. Biomaterials. 2011;32:9300-7 pubmed publisher
    ..This makes CSS vesicle a promising carrier for the treatment of cancer, especially for leukemia...
  48. Ahmad M, Liew S, Yarmo M, Said M. Optimization of protease extraction from horse mango (Mangifera foetida Lour) kernels by a response surface methodology. Biosci Biotechnol Biochem. 2012;76:1438-44 pubmed
    ..Based on the t-value, the effects of the variables arranged in ascending order of strength were CaCl(2) < pH < DTT < Triton X-100...
  49. Dimitrijević A, Veličković D, Bihelovic F, Bezbradica D, Jankov R, Milosavić N. One-step, inexpensive high yield strategy for Candida antarctica lipase A isolation using hydroxyapatite. Bioresour Technol. 2012;107:358-62 pubmed publisher
    ..Detergents at 0.1% concentrations did not affect lipase activity. Except for Triton X-100, detergent concentrations of 1% had a destabilizing effect...
  50. Zhang Z, Meng Q, Qiao J, Yang L, Cai X, Wang G, et al. RsbV of Listeria monocytogenes contributes to regulation of environmental stress and virulence. Arch Microbiol. 2013;195:113-20 pubmed publisher
    ..monocytogenes. Our data demonstrate that, in addition to regulating tolerance under environmental stress conditions, RsbV also contributes to regulation of L. monocytogenes virulence...
  51. Lago Vanzela E, Pavezzi F, Martin N, Gomes E, Da Silva R. Isolation and characterization of latent and active polyphenoloxidase in BRS Clara (CNPUV 154-147 × Centennial seedless) and BRS Morena (Marroo seedless × Centennial seedless) seedless table grapes. Plant Physiol Biochem. 2011;49:1251-8 pubmed publisher
    ..The PPO from grapes extracted with Triton-X-114 was activated with 0.2% of the ionic detergent sodium dodecyl sulfate (SDS), and exhibited maximum activities at pH 5.5 and at 30 °C. It was stable until the temperature reached 60 °C...
  52. Yamashita A, Tanaka K, Kamata R, Kumazawa T, Suzuki N, Koga H, et al. Subcellular localization and lysophospholipase/transacylation activities of human group IVC phospholipase A2 (cPLA2gamma). Biochim Biophys Acta. 2009;1791:1011-22 pubmed publisher
    ..As lysophospholipids are known to accumulate in ischemia heart and to induce arryhthmia, the cPLA2gamma that is abundant in heart may have a protective role through clearance of lysophospholipids by its transacylation activity...
  53. Iyer R, Kapoor D. Diagnosis of spontaneous bacterial peritonitis: Role of tween 80 and triton X in ascitic fluid cultures. Indian J Med Microbiol. 2009;27:159-61 pubmed publisher
    ..Thus, the use of the aforementioned agents could be explored in elucidating the aetiology of body cavity infections when conventional methods fail...