alcohols

Summary

Summary: Alkyl compounds containing a hydroxyl group. They are classified according to relation of the carbon atom: primary alcohols, R-CH2OH; secondary alcohols, R2-CHOH; tertiary alcohols, R3-COH. (From Grant & Hackh's Chemical Dictionary, 5th ed)

Top Publications

  1. Silverio D, Torker S, Pilyugina T, Vieira E, Snapper M, Haeffner F, et al. Simple organic molecules as catalysts for enantioselective synthesis of amines and alcohols. Nature. 2013;494:216-21 pubmed publisher
    ..reagents with imines and carbonyls; the products of the reactions are enantiomerically pure amines and alcohols, which might serve as intermediates in the preparation of biologically active molecules...
  2. Choi B, Cha B, Yagyu T, Woo J, Ojika M. Sponge-derived acetylenic alcohols, petrosiols, inhibit proliferation and migration of platelet-derived growth factor (PDGF)-induced vascular smooth muscle cells. Bioorg Med Chem. 2013;21:1804-10 pubmed publisher
    ..Furthermore, petrosiol A (1) suppressed PDGF-induced actin filament dissociation and cell migration, suggesting that 1 and its derivatives may be used for the prevention and treatment of vascular diseases...
  3. Avalos J, Fink G, Stephanopoulos G. Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols. Nat Biotechnol. 2013;31:335-41 pubmed publisher
    ..Other benefits of compartmentalization may include increased availability of intermediates, removing the need to transport intermediates out of the mitochondrion and reducing the loss of intermediates to competing pathways...
  4. Gołębiowski M, Cerkowniak M, Dawgul M, Kamysz W, Boguś M, Stepnowski P. The antifungal activity of the cuticular and internal fatty acid methyl esters and alcohols in Calliphora vomitoria. Parasitology. 2013;140:972-85 pubmed publisher
    ..Seven FAMEs from C13:0 to C19:0 were identified in the internal lipids of females, and 7, 6, 5 and 3 alcohols were found in the cuticular lipids of larvae, pupae, males and females respectively...
  5. Zhang E, Tian H, Xu S, Yu X, Xu Q. Iron-catalyzed direct synthesis of imines from amines or alcohols and amines via aerobic oxidative reactions under air. Org Lett. 2013;15:2704-7 pubmed publisher
    ..catalyzed the aerobic oxidative reactions of primary amines, secondary amines, benzylamines with anilines, and alcohols with amines by directly using air as the economic and safe oxidant, providing several direct, practical, and ..
  6. Moretti A, Zerba E, Alzogaray R. Behavioral and toxicological responses of Rhodnius prolixus and Triatoma infestans (Hemiptera: Reduviidae) to 10 monoterpene alcohols. J Med Entomol. 2013;50:1046-54 pubmed
    The effect on locomotor activity, the repellency, and the knock-down produced by 10 monoterpene alcohols were evaluated on first-instar nymphs of Rhodnius prolixus and Triatoma infestans, vectors of Chagas disease...
  7. Mayfield J, Ferguson L, Harris R. Neuroimmune signaling: a key component of alcohol abuse. Curr Opin Neurobiol. 2013;23:513-20 pubmed publisher
  8. Zhang Z, Ma Y, Wang Q, Chen A, Pan Z, Li G. Preparation of novel alumina nanowire solid-phase microextraction fiber coating for ultra-selective determination of volatile esters and alcohols from complicated food samples. J Chromatogr A. 2013;1290:27-35 pubmed publisher
    ..a simple and rapid anodization-chemical etching method for ultra-selective determination of volatile esters and alcohols from complicated food samples...
  9. Bartoszewicz A, Ahlsten N, Martín Matute B. Enantioselective synthesis of alcohols and amines by iridium-catalyzed hydrogenation, transfer hydrogenation, and related processes. Chemistry. 2013;19:7274-302 pubmed publisher
    The preparation of chiral alcohols and amines by using iridium catalysis is reviewed...

Scientific Experts

More Information

Publications62

  1. Mei T, Werner E, Burckle A, Sigman M. Enantioselective redox-relay oxidative heck arylations of acyclic alkenyl alcohols using boronic acids. J Am Chem Soc. 2013;135:6830-3 pubmed publisher
    ..A preliminary mechanistic investigation suggests that the regioselectivity of the initial migratory insertion is highly dependent on the electronic nature of the boronic acid and more subtle electronic effects of the alkenyl alcohol...
  2. Flores Rizo J, Esnal I, Osorio Martínez C, Gómez Durán C, Bañuelos J, Lopez Arbeloa I, et al. 8-Alkoxy- and 8-aryloxy-BODIPYs: straightforward fluorescent tagging of alcohols and phenols. J Org Chem. 2013;78:5867-77 pubmed publisher
    We demonstrate herein that both alcohols and phenols can be tagged with a BODIPY (borondipyrromethene) moiety to yield highly fluorescent products...
  3. Jozwiak A, Brzozowski R, Bujnowski Z, Chojnacki T, Swiezewska E. Application of supercritical CO2 for extraction of polyisoprenoid alcohols and their esters from plant tissues. J Lipid Res. 2013;54:2023-8 pubmed publisher
    ..g., polyisoprenoid phosphates...
  4. Takeda K, Matsumura H, Ishida T, Samejima M, Igarashi K, Nakamura N, et al. The two-step electrochemical oxidation of alcohols using a novel recombinant PQQ alcohol dehydrogenase as a catalyst for a bioanode. Bioelectrochemistry. 2013;94:75-8 pubmed publisher
    ..PpADH exhibited broad substrate specificity towards various alcohols and aldehydes...
  5. Lomonaco T, Ghimenti S, Piga I, Onor M, Melai B, Fuoco R, et al. Determination of total and unbound warfarin and warfarin alcohols in human plasma by high performance liquid chromatography with fluorescence detection. J Chromatogr A. 2013;1314:54-62 pubmed publisher
    ..are presented for the determination of the total content and unbound fraction of both warfarin and warfarin alcohols in human plasma...
  6. Lackner G, Quasdorf K, Overman L. Direct construction of quaternary carbons from tertiary alcohols via photoredox-catalyzed fragmentation of tert-alkyl N-phthalimidoyl oxalates. J Am Chem Soc. 2013;135:15342-5 pubmed publisher
    A convenient method for the direct construction of quaternary carbons from tertiary alcohols by visible-light photoredox coupling of tert-alkyl N-phthalimidoyl oxalate intermediates with electron-deficient alkenes is reported.
  7. Sonmez M, Ince H, Yalcin O, Ajdžanović V, Spasojevic I, Meiselman H, et al. The effect of alcohols on red blood cell mechanical properties and membrane fluidity depends on their molecular size. PLoS ONE. 2013;8:e76579 pubmed publisher
    ..evaluated alterations of RBC membrane fluidity, deformability and stability in the presence of four linear alcohols (methanol, ethanol, propanol and butanol) using ektacytometry and electron paramagnetic resonance (EPR) ..
  8. Kyne R, Ryan M, Kliman L, Morken J. Allylation of nitrosobenzene with pinacol allylboronates. A regioselective complement to peroxide oxidation. Org Lett. 2010;12:3796-9 pubmed publisher
    ..Remarkably, the N-O bond is cleaved during the reaction such that simple alcohols are the final reaction product.
  9. Simmons E, Hartwig J. Catalytic functionalization of unactivated primary C-H bonds directed by an alcohol. Nature. 2012;483:70-3 pubmed publisher
    ..The scope of the reaction encompasses alcohols and ketones bearing many substitution patterns and auxiliary functional groups; this broad scope suggests that ..
  10. Yoo H, Washington J, Ellington J, Jenkins T, Neill M. Concentrations, distribution, and persistence of fluorotelomer alcohols in sludge-applied soils near Decatur, Alabama, USA. Environ Sci Technol. 2010;44:8397-402 pubmed publisher
    ..85 to 1.8 years. These analytical results show that the practice of sludge application to land is a pathway for the introduction of FTOHs and, accordingly, their transformation products, perfluorocarboxylic acids, into the environment...
  11. Nierth A, Jäschke A. Radioactive phosphorylation of alcohols to monitor biocatalytic Diels-Alder reactions. PLoS ONE. 2011;6:e21391 pubmed publisher
    ..The phosphorylation strategy with trichloroacetonitrile may be applicable for labeling numerous other compounds that contain alcoholic hydroxyl groups...
  12. Dai C, Narayanam J, Stephenson C. Visible-light-mediated conversion of alcohols to halides. Nat Chem. 2011;3:140-5 pubmed publisher
    ..Here, we report a visible-light-mediated photocatalytic alcohol activation, which we use to convert alcohols to the corresponding bromides and iodides in good yields, with exceptional functional group tolerance...
  13. Spell M, Wang X, Wahba A, Conner E, Ragains J. An ?-selective, visible light photocatalytic glycosylation of alcohols with selenoglycosides. Carbohydr Res. 2013;369:42-7 pubmed publisher
    ..Reactions afford, in all cases, primarily the ?-anomers with selectivities that vary with solvent. This represents the first example of a visible light-promoted O-glycosylation...
  14. Watson A, Maxwell A, Williams J. Ruthenium-catalysed oxidative synthesis of heterocycles from alcohols. Org Biomol Chem. 2012;10:240-3 pubmed publisher
    Ruthenium-catalysed hydrogen transfer has been successfully used for the conversion of alcohols into either 2,3-dihydroquinazolines or quinazolines...
  15. Tezvergil Mutluay A, Agee K, Hoshika T, Uchiyama T, Tjäderhane L, Breschi L, et al. Inhibition of MMPs by alcohols. Dent Mater. 2011;27:926-33 pubmed publisher
    ..When ethanol solvent controls were run, they were found to partially inhibit MMPs. Thus, the purpose of this study was to compare the MMP-inhibitory activity of a series of alcohols.
  16. Chou H, Keasling J. Synthetic pathway for production of five-carbon alcohols from isopentenyl diphosphate. Appl Environ Microbiol. 2012;78:7849-55 pubmed publisher
    ..Taken together, our work demonstrates a new approach to the engineering of novel synthetic pathways in the cell...
  17. Vuluga D, Legros J, Crousse B, Slawin A, Laurence C, Nicolet P, et al. Influence of the structure of polyfluorinated alcohols on Brønsted acidity/hydrogen-bond donor ability and consequences on the promoter effect. J Org Chem. 2011;76:1126-33 pubmed publisher
    The influence of substituents on the properties of tri- and hexafluorinated alcohols derived from 2,2,2-trifluoroethanol (TFE) and 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) was examined...
  18. Bisogno F, Lavandera I, Kroutil W, Gotor V. Tandem concurrent processes: one-pot single-catalyst biohydrogen transfer for the simultaneous preparation of enantiopure secondary alcohols. J Org Chem. 2009;74:1730-2 pubmed publisher
    A novel one-pot tandem biohydrogen transfer process to concurrently obtain two enantiopure sec-alcohols is presented; thus, using a suitable single enzyme and a catalytic amount of cofactor, several interesting building blocks could be ..
  19. Kaier K, Hagist C, Frank U, Conrad A, Meyer E. Two time-series analyses of the impact of antibiotic consumption and alcohol-based hand disinfection on the incidences of nosocomial methicillin-resistant Staphylococcus aureus infection and Clostridium difficile infection. Infect Control Hosp Epidemiol. 2009;30:346-53 pubmed publisher
    ..To determine the impact of antibiotic consumption and alcohol-based hand disinfection on the incidences of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection and Clostridium difficile infection (CDI)...
  20. Taylor E, Campbell S, Griffiths C, Reid P, Slaven J, Harrison R, et al. Fusel alcohols regulate translation initiation by inhibiting eIF2B to reduce ternary complex in a mechanism that may involve altering the integrity and dynamics of the eIF2B body. Mol Biol Cell. 2010;21:2202-16 pubmed publisher
    ..Here we show that eIF2B serves as the target for translation inhibition by various fusel alcohols in yeast. Fusel alcohols are endpoint metabolites from amino acid catabolism, which signal nitrogen scarcity...
  21. Fischer A, Makowski P, Müller J, Antonietti M, Thomas A, Goettmann F. High-surface-area TiO2 and TiN as catalysts for the C-C coupling of alcohols and ketones. ChemSusChem. 2008;1:444-9 pubmed publisher
    ..as well as the initial oxide proved to be effective and versatile catalysts for the alkylation of ketones with alcohols. Interestingly, the TiN catalyst yields unsaturated compounds, while the oxide-based catalyst mainly yields ..
  22. Rodriguez P, Kwon Y, Koper M. The promoting effect of adsorbed carbon monoxide on the oxidation of alcohols on a gold catalyst. Nat Chem. 2011;4:177-82 pubmed publisher
    ..adsorbed carbon monoxide typically acts as a poison or poisoning intermediate in the oxidation of alcohols. However, gold as an (electro)catalyst often exhibits unexpected properties...
  23. Wang B, Shi A, Tu R, Zhang X, Wang Q, Bai F. Branched-chain higher alcohols. Adv Biochem Eng Biotechnol. 2012;128:101-18 pubmed publisher
    ..Compared with fuel ethanol, branched-chain higher alcohols (BCHAs), including isopropanol, isobutanol, 2-methyl-1-butanol, and 3-methyl-1-butanol, exhibit significant ..
  24. GARCIA C, Piñero L, Oyola R, Arce R. Photodegradation of 2-chloro substituted phenothiazines in alcohols. Photochem Photobiol. 2009;85:160-70 pubmed publisher
    ..phenothiazines and their phototoxic activity, their photophysics and photochemistry were studied in several alcohols. The photodestruction quantum yields were determined under anaerobic conditions using monochromatic light (313 nm)..
  25. Dellomonaco C, Clomburg J, Miller E, Gonzalez R. Engineered reversal of the ?-oxidation cycle for the synthesis of fuels and chemicals. Nature. 2011;476:355-9 pubmed publisher
    ..that a functional reversal of the ?-oxidation cycle can be used as a metabolic platform for the synthesis of alcohols and carboxylic acids with various chain lengths and functionalities...
  26. Gao X, Jung W, Kuk J, Park R. Reaction pattern of Bacillus cereus D-11 chitosanase on chitooligosaccharide alcohols. J Microbiol Biotechnol. 2009;19:358-61 pubmed
    ..To further investigate the cleavage pattern of this enzyme, chitooligosaccharide alcohols were prepared as substrates and the end products of hydrolysis were analyzed by TLC and HPLC...
  27. Rude M, Schirmer A. New microbial fuels: a biotech perspective. Curr Opin Microbiol. 2009;12:274-81 pubmed publisher
  28. Trincado M, Grützmacher H, Vizza F, Bianchini C. Domino rhodium/palladium-catalyzed dehydrogenation reactions of alcohols to acids by hydrogen transfer to inactivated alkenes. Chemistry. 2010;16:2751-7 pubmed publisher
    ..heterogeneous catalyst results in the formation of a superior catalyst system for the dehydrogenative coupling of alcohols. The overall process represents a mild and direct method for the synthesis of aromatic and heteroaromatic ..
  29. Morito A, Fujisawa K, Eguchi T, Ota Y. Protective effects of polysaccharides and polyhydric alcohols in a dry mouth model in cultured cells. Support Care Cancer. 2012;20:725-31 pubmed publisher
    The goal of the study was to investigate the effects of 21 polysaccharides and 12 polyhydric alcohols on inhibition of dryness in oral mucosal epithelial cells in vitro. All the tested compounds are currently used in oral products.
  30. Hamzic M, Pietruszka J, Sandkuhl D. HPLC-CD selectivity assay for alcohol dehydrogenases. Chirality. 2011;23 Suppl 1:E110-5 pubmed publisher
    ..liquid chromatography and circular dichroism to find a suitable system for providing enantiomerically pure alcohols. This investigation led to an efficient protocol for the alcohol dehydrogenase-catalyzed reduction of 1-phenyl-2-..
  31. Li X, Borhan B. Prompt determination of absolute configuration for epoxy alcohols via exciton chirality protocol. J Am Chem Soc. 2008;130:16126-7 pubmed publisher
    A microscale protocol for determination of absolute configurations of 2,3-epoxy alcohols is described...
  32. Wen M, Jetter R. Composition of secondary alcohols, ketones, alkanediols, and ketols in Arabidopsis thaliana cuticular waxes. J Exp Bot. 2009;60:1811-21 pubmed publisher
    ..containing secondary functional groups were examined (i) to test the biosynthetic relationship between secondary alcohols and ketols and (ii) to determine the regiospecificity and substrate preference of the enzyme involved in ketol ..
  33. Zang J, Konduri S, Nair S, Sholl D. Self-diffusion of water and simple alcohols in single-walled aluminosilicate nanotubes. ACS Nano. 2009;3:1548-56 pubmed publisher
    ..D(s) values of water in an analogous aluminogermanate NT are larger than those in the aluminosilicate NT due to a larger pore diameter...
  34. Reichel M, Heisig P, Kohlmann T, Kampf G. Alcohols for skin antisepsis at clinically relevant skin sites. Antimicrob Agents Chemother. 2009;53:4778-82 pubmed publisher
    ..Further studies are needed to determine the most effective concentration of CHG in n-propanol to provide the best protection against recolonization of the skin, e.g., for catheter site care...
  35. Hübner N, Hübner C, Wodny M, Kampf G, Kramer A. Effectiveness of alcohol-based hand disinfectants in a public administration: impact on health and work performance related to acute respiratory symptoms and diarrhoea. BMC Infect Dis. 2010;10:250 pubmed publisher
    ..Hand disinfection is acknowledged as key element for infection control, but its effect in open, work place settings is unclear...
  36. Phillips E, Riedrich M, Scheidt K. N-heterocyclic carbene-catalyzed conjugate additions of alcohols. J Am Chem Soc. 2010;132:13179-81 pubmed publisher
    An efficient intermolecular conjugate addition of alcohols to activated alkenes catalyzed by N-heterocyclic carbenes has been developed...
  37. Brandsma S, Smithwick M, Solomon K, Small J, de Boer J, Muir D. Dietary exposure of rainbow trout to 8:2 and 10:2 fluorotelomer alcohols and perfluorooctanesulfonamide: Uptake, transformation and elimination. Chemosphere. 2011;82:253-8 pubmed publisher
    The bioaccumulation of perfluorooctanesulfonamide (PFOSA) and two fluorotelomer alcohols (8:2 FTOH, 10:2 FTOH) by rainbow trout (Oncorhynchus mykiss) through dietary exposure, including depuration rates and metabolism was investigated...
  38. Bassolé I, Lamien Meda A, Bayala B, Tirogo S, Franz C, Novak J, et al. Composition and antimicrobial activities of Lippia multiflora Moldenke, Mentha x piperita L. and Ocimum basilicum L. essential oils and their major monoterpene alcohols alone and in combination. Molecules. 2010;15:7825-39 pubmed publisher
    ..x piperita and, linalool and eugenol for O. basilicum. The essential oils and their major monoterpene alcohols were tested against nine bacterial strains using the disc diffusion and broth microdilution methods...
  39. Wu X, Zhang C, Orita I, Imanaka T, Fukui T, Xing X. Thermostable alcohol dehydrogenase from Thermococcus kodakarensis KOD1 for enantioselective bioconversion of aromatic secondary alcohols. Appl Environ Microbiol. 2013;79:2209-17 pubmed publisher
    A novel thermostable alcohol dehydrogenase (ADH) showing activity toward aromatic secondary alcohols was identified from the hyperthermophilic archaeon Thermococcus kodakarensis KOD1 (TkADH)...
  40. Wang L, Li C, Ni Y, Zhang J, Liu X, Xu J. Highly efficient synthesis of chiral alcohols with a novel NADH-dependent reductase from Streptomyces coelicolor. Bioresour Technol. 2011;102:7023-8 pubmed publisher
    ..These results indicate the potential of ScCR for the industrial production of valuable chiral alcohols.
  41. Maenaka Y, Suenobu T, Fukuzumi S. Hydrogen evolution from aliphatic alcohols and 1,4-selective hydrogenation of NAD+ catalyzed by a [C,N] and a [C,C] cyclometalated organoiridium complex at room temperature in water. J Am Chem Soc. 2012;134:9417-27 pubmed publisher
    ..acid-?C(3))(H(2)O)](2)SO(4) [1](2)·SO(4), was reduced by aliphatic alcohols to produce the corresponding hydride complex [Ir(III)(Cp*)(4-(1H-pyrazol-1-yl-?N(2))-benzoate-?C(3))H](-)4 at ..
  42. Sashi P, Yasin U, Bhuyan A. Unfolding action of alcohols on a highly negatively charged state of cytochrome C. Biochemistry. 2012;51:3273-83 pubmed publisher
    ..Studies with extremely alkaline cytochrome c (U(B) state, pH 13) in the presence of the first four alkyl alcohols suggests that the hydrophobic effect persistently overrides even though the protein carries a net charge of -17 ..
  43. Styler S, Donaldson D. Photooxidation of atmospheric alcohols on laboratory proxies for mineral dust. Environ Sci Technol. 2011;45:10004-12 pubmed publisher
    ..These observations suggest that mineral dust containing photoactive components may catalyze the transformation of photochemically inactive organic compounds into species that absorb in the actinic region...
  44. Yu C, Cao Y, Zou H, Xian M. Metabolic engineering of Escherichia coli for biotechnological production of high-value organic acids and alcohols. Appl Microbiol Biotechnol. 2011;89:573-83 pubmed publisher
    ..of high-value organic acids like succinic acid, lactic acid, 3-hydroxypropanoic acid and glucaric acid as well as alcohols like 1,3-propanediol, xylitol, mannitol, and glycerol with the discussion of the future research in this area...
  45. Elliott M, Smith K, Jones D, Hussain A, Saleh B. Factors affecting migration of tertiary alkyl groups in reactions of alkylboronic esters with bromomethyllithium. J Org Chem. 2013;78:3057-64 pubmed publisher
    ..Based on this, experimental protocols have been devised in which the competing reactions are largely suppressed, leading to higher conversions to migrated product for several substrates...
  46. Nilsson H, Karrman A, Rotander A, van Bavel B, Lindstrom G, Westberg H. Inhalation exposure to fluorotelomer alcohols yield perfluorocarboxylates in human blood?. Environ Sci Technol. 2010;44:7717-22 pubmed publisher
    ..of this follow-up study was to determine concentrations of PFCAs, perfluorosulfonates (PFSAs), and fluorotelomer alcohols (FTOHs), precursor compounds that are known to degrade to PFCAs, in air collected in the breathing zone of ski ..
  47. Yu H, Oyama T, Isse T, Kitagawa K, Pham T, Tanaka M, et al. Formation of acetaldehyde-derived DNA adducts due to alcohol exposure. Chem Biol Interact. 2010;188:367-75 pubmed publisher
    ..Future studies are needed to better characterize and to validate the roles of these DNA adducts in human study...
  48. Perez J, Richter H, Loftus S, Angenent L. Biocatalytic reduction of short-chain carboxylic acids into their corresponding alcohols with syngas fermentation. Biotechnol Bioeng. 2013;110:1066-77 pubmed publisher
    ..While conversion of carboxylic acids into alcohols is routinely performed with catalytic hydrogenation or with strong chemical reducing agents, here, a biological ..
  49. Perez Y, Oyarzabal A, Mas R, Molina V, Jimenez S. Protective effect of D-002, a mixture of beeswax alcohols, against indomethacin-induced gastric ulcers and mechanism of action. J Nat Med. 2013;67:182-9 pubmed publisher
    D-002, a mixture of higher aliphatic beeswax alcohols, produces gastroprotective and antioxidant effects...
  50. Schober M, Gadler P, Knaus T, Kayer H, Birner Grünberger R, Gülly C, et al. A stereoselective inverting sec-alkylsulfatase for the deracemization of sec-alcohols. Org Lett. 2011;13:4296-9 pubmed publisher
    ..This catalytic event, which does not have an analog in chemocatalysis, yields homochiral (S)-configurated alcohols and nonreacted sulfate esters...
  51. Jiang Q, Wang W, Zhang Z, Zhang L. Binding specificity of locust odorant binding protein and its key binding site for initial recognition of alcohols. Insect Biochem Mol Biol. 2009;39:440-7 pubmed publisher
    ..We suggest that, as a general rule, a hydrophilic amino acid at the entrance of the binding cavity participates in initial recognition of ligands, and contributes to ligand-binding specificity of OBPs...
  52. Komatsu T, Uchida K, Fujita F, Zhou Y, Tominaga M. Primary alcohols activate human TRPA1 channel in a carbon chain length-dependent manner. Pflugers Arch. 2012;463:549-59 pubmed publisher
    ..Here, we show that primary alcohols, which have been reported to cause skin, eye or nasal irritation, activate human TRPA1 (hTRPA1)...
  53. Ingolfsson H, Andersen O. Alcohol's effects on lipid bilayer properties. Biophys J. 2011;101:847-55 pubmed publisher
    b>Alcohols are known modulators of lipid bilayer properties. Their biological effects have long been attributed to their bilayer-modifying effects, but alcohols can also alter protein function through direct protein interactions...