guided tissue regeneration

..with the Perlecan D1 expression construct, and to test the Perlecan D1 expression construct in guided tissue regeneration. Structural modeling has allowed rational design for site-directed mutagenesis of the Perlecan D1 core ..

..with the Perlecan D1 expression construct, and to test the Perlecan D1 expression construct in guided tissue regeneration. Structural modeling has allowed rational design for site-directed mutagenesis of the Perlecan D1 core ..

..Identification of factors which influences the incorporation and remodeling of tissue engineered transplants will lead to significantly improved and more reliable biomimetic therapies...

..b>Guided tissue regeneration (GTR) techniques are increasingly being used for the treatment of periodontal defects, or in conjunction ..

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..the efficacy and safety of reconstructing alveolar bone defects with demineralized bone powder (DBP) or guided tissue regeneration (GTR) techniques in a 3rd molar extraction surgical model...

Functional graded materials (FGM) provided us one new concept for guided tissue regeneration (GTR) membrane design with graded component and graded structure where one face of the membrane is porous thereby allowing cell growth thereon ..

..We concluded from current study that the membrane had satisfactory biocompatibility and the constructs could be used to guided bone regeneration...

..Electrical poling was shown to promote neurite growth, axon regeneration and the conduction rate of the repaired nerve. We concluded that guides prepared with electrical poling enhance peripheral nerve regeneration...

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..CONCLUSION: Further investigation of the prototype membrane that showed prolonged membrane integrity to evaluate its potential in GBR procedures is needed...

..The present preliminary study shows the proof of principles that porous, resorbable, bioactive SCPC-rhBMP-2 tissue engineering hybrid can serve as a substitute for autologous bone in load-bearing applications...

..These results suggested that the biodegradable composite membrane containing oriented needle-like apatite had excellent biocompatibility with both soft and hard tissues...

..prevent down-growth of the oral mucosa along the root surface and to allow alveolar bone regeneration in guided tissue regeneration. Several studies have demonstrated bone regenerates in the presence of bioabsorbable and non-resorbable ..

..The structure of the novel PLGA scaffolds provided architectural support for the differentiation of progenitor cells and demonstrated successful induction of in vivo chondrogenesis...

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..This paper is unique because resorbable material in the animal model is relatively inexpensive and easy to use and has allowed successful autogenous bony regeneration...

..These scaffolds could be useful for guiding regeneration of the peripheral nerve or spinal cord after a transection injury...

..The conduction velocity and recovery index improved significantly after 5 months reaching the normal values in the autograft and MWI crosslinked collagen groups compared to GTA and uncrosslinked collagen tubes...

..It could be applied as an ideal membrane for inducing bone regeneration...

..Histology confirmed a better integration between new bone and scaffold in the Si-TCP composites in comparison to 100% HA composites where new bone and scaffold phases remained well distinct...

..The molecular weight of both membranes decreased steadily from 170,000 D to 30,000 D. It was concluded that the mechanical requirements for a membrane for GBR were fulfilled by the composite membrane...

..This study demonstrates that endowing scaffolds with a sensing element could provide an on-line and non-destructive monitoring method for tissue engineering...

..Of course more studies with the control groups are needed for the evaluation of this method as a clinical solution for the patients...

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..This study has demonstrated that the pore size and structure of the supercritical PDLLA and PLGA scaffolds can be tailored by careful control of processing conditions...

..Bone regeneration, evaluated by radiological and pathological parameters, was seen in both groups. In the EC group the process was faster but was followed by a sharp decrease, whereas in the CH group it was slower and continuous...

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..Infection control measures should be developed in tissue engineering to avoid further complications when TE devices emerge clinically...

..The porosity which was determined by calculation and microtomography was between 84% and 88%. Reduced cracks and thicker struts were observed in the microstructure, pointing to improved mechanical properties...

..Based on these results, we conclude that tyrosine polycarbonate is a promising new material for guided bone regeneration...

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..Long-term studies or accelerated degradation studies are required to confirm the expected advantages of poly(L/DL-lactide) 80:20...

..Donor site morbidity can be avoided. Similarly to nerve transplantation, the operation requires microsurgical skills...

..However, no prospective studies comparing the available nerve conduits have been published...

..The collagen fibers of a GBR-membrane appear to participate in osteogenic differentiation...

..The AA-grafted porous polymer scaffolds were effective for cell adhesion and differentiation, making them a suitable platform for tissue-engineered cartilage...

..This scaffold may be useful to regenerate cartilaginous tissues through minimally invasive surgical procedures in orthopedic, maxillofacial, and urologic applications...

..CONCLUSIONS: This study suggests the feasibility of using PRP as injectable scaffold seeded with chondrocytes to regenerate cartilage and showed the potential of using this method for the reconstruction of cartilage defects...

..The combined use with deproteinized bovine bone mineral and/or enamel matrix proteins did not significantly enhance the potential for complete healing provided by the GBR procedure...

..These findings indicated the compatibility of this hydrogel with brain tissue. Collectively, the results demonstrate the promise of an HA-PDL hydrogel as a scaffold material for the repair of defects in the brain...

..Although, nowadays, nerve regeneration materials being marketed mostly have a tubular structure, our results suggest that the tubular structure is not indispensable for peripheral nerve regeneration...

..We concluded that the combination of autologous PCBM, a vessel bundle, and a biodegradable membrane was promising in the prefabrication of vascularized bone with good blood circulation...

..05) in the early period. CAF induced dense bone formation, whereas CM produced less newly formed bone. CONCLUSION: CAF is more efficacious than CM in guided bone regeneration in this animal model...

..Further investigation of the use of the collagen BioSISt membrane for cranial bone augmentation is warranted...

..Sodium hydroxide-treated membranes demonstrated increased cell attachment resulting from increased hydrophilicity. CONCLUSION: These findings have potential application in the development of a new generation of osteoconductive membranes...

..Micropatterning on the membrane surface can affect the distribution of cells and the communication among cells, and results in a difference in cell adhesion, morphology, mobility, and growth activity...

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..These results may be due both to an initially increased number of macrophages surrounding the slower degrading membranes and to the maintenance of their initial pore structure...

..presenting advanced intrabony defects (8 to 15 mm) meeting the predetermined criteria were treated by guided tissue regeneration (GTR) with flap debridement and placement of a bioabsorbable copolymer membrane...

..Presence of chemical cues and micropatterns on the surface enhance cell orientation and bone formation...

..This differed significantly from the much lower compression resistance seen in the unadulterated BioOss [0.92 MPa (SD+/-0.04)]. Following this, the in vivo engineered bone has a similar mechanical compression stability as natural bone...

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..Bioactive glass foam scaffolds sintered at 800 degrees C for 2 h fulfill the criteria for an ideal scaffold for tissue engineering applications...

..CONCLUSION: Silk fibroin film can promote the repair of urethral defect by inducing the growth of the urethral epithelial cells and smooth muscle cells...

..The use of a bioabsorbable membrane around immediately placed transmucosal implants enhanced soft and hard tissue healing and might be an advisable treatment choice particularly in areas with high esthetic demands...

..It was shown that newly developed hybrid-polymer fibre scaffold has feasibility for joint tissue engineering...

..Good viability of cells seeded in the porous scaffolds was confirmed. This novel fabrication method is promising in tissue engineering because of its ability to produce precise and complexly (anatomically) shaped porous scaffolds...

..Additionally, growth of cells on the vertical surfaces of 3D structures composed of ORMOCER is shown...

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..This paper will specifically illustrate the use of microcomputed tomography (micro-CT) imaging with and without contrast agents to nondestructively quantify the formation of bone, cartilage, and vasculature within porous biomaterials...

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..This study demonstrates the promise of electrospinning as a fabrication process for a functional vascular graft for clinical use...

..2 degrees in controls. The morphology of the cells was also affected by the PDMS scaffold. The nuclei were longer (1.25x) and thinner (0.75x) than in control gels; however, no changes in diameter of the cells in the z direction were seen...

..Collagen-alginate hydrogels appear to be promising materials for VF restoration, warranting further investigation...