median neuropathy


Summary: Disease involving the median nerve, from its origin at the BRACHIAL PLEXUS to its termination in the hand. Clinical features include weakness of wrist and finger flexion, forearm pronation, thenar abduction, and loss of sensation over the lateral palm, first three fingers, and radial half of the ring finger. Common sites of injury include the elbow, where the nerve passes through the two heads of the pronator teres muscle (pronator syndrome) and in the carpal tunnel (CARPAL TUNNEL SYNDROME).

Top Publications

  1. Heckmann J, Dutsch M, Buslei R. Hereditary neuropathy with liability to pressure palsy combined with schwannomas of the median and medial plantar nerves. Muscle Nerve. 2007;35:122-4 pubmed
    ..The occurrence of HNPP and schwannomas in the same patient might be purely coincidental, but it is tempting to speculate that they share a common genetic basis...
  2. Armstrong T, Dale A, Franzblau A, Evanoff B. Risk factors for carpal tunnel syndrome and median neuropathy in a working population. J Occup Environ Med. 2008;50:1355-64 pubmed publisher
    ..To assess whether work-related physical activities are associated with Carpal tunnel syndrome (CTS), even when controlling for personal risk factors...
  3. Elliott M, Barr A, Clark B, Wade C, Barbe M. Performance of a repetitive task by aged rats leads to median neuropathy and spinal cord inflammation with associated sensorimotor declines. Neuroscience. 2010;170:929-41 pubmed publisher
    ..Thus, aged rats performing a repetitive task exhibited sensorimotor declines that were associated with decreased median nerve conduction, and increased pro-inflammatory cytokines in the median nerve and cervical spinal cord neurons...
  4. Imada M, Misawa S, Sawai S, Tamura N, Kanai K, Sakurai K, et al. Median-radial sensory nerve comparative studies in the detection of median neuropathy at the wrist in diabetic patients. Clin Neurophysiol. 2007;118:1405-9 pubmed
    ..This study tested the utility of median-radial comparative studies (MRCS) in diabetic patients...
  5. Akansel G, Dalbayrak S, Yilmaz M, Bekler H, Arslan A. MRI demonstration of intra-articular median nerve entrapment after elbow dislocation. Skeletal Radiol. 2003;32:537-41 pubmed
    ..We report a case of median nerve entrapment in the elbow joint diagnosed with MRI 14 months after closed reduction of a dislocated elbow joint. ..
  6. Sesek R, Khalighi M, Bloswick D, Anderson M, Tuckett R. Effects of prolonged wrist flexion on transmission of sensory information in carpal tunnel syndrome. J Pain. 2007;8:137-51 pubmed
  7. Lafon L, Lautman S, Corcia P, Laulan J. [Proximal median nerve compression. A series of 35 consecutive cases]. Chir Main. 2013;32:147-53 pubmed publisher
    ..If no improvement occurs, surgical treatment should be proposed, one must then assess all potential sites of nerve entrapment. Patients must be informed that improvement can take several years. ..
  8. Anderson J, Lucas G, Buhr B. Complications of treating distal radius fractures with external fixation: a community experience. Iowa Orthop J. 2004;24:53-9 pubmed
    ..Their effect, however, on long term functional results and patient satisfaction is negligible, with the exception of those patients with complications intrinsic to the fracture itself, i.e., nonunion, malunion or carpal malalignment. ..
  9. Pruzansky M. Compression of the radial branch of the median nerve due to an anomalous muscle belly of the first lumbrical in a child. Mt Sinai J Med. 2004;71:285-6 pubmed
    ..Provocative signs and symptoms in the distribution of only the radial branch of the median nerve are the most important signs distinguishing this case from carpal tunnel syndrome. ..

More Information

Publications108 found, 100 shown here

  1. Ko C, Brown T. A fluid-immersed multi-body contact finite element formulation for median nerve stress in the carpal tunnel. Comput Methods Biomech Biomed Engin. 2007;10:343-9 pubmed
    ..The effects of pertinent physical parameters on median nerve stress were explored. The results suggest that median nerve stresses due to direct structural contact are typically far higher than those from fluid pressure. ..
  2. Ray W, Mackinnon S. Clinical outcomes following median to radial nerve transfers. J Hand Surg Am. 2011;36:201-8 pubmed publisher
    ..The important nuances of both surgical technique and motor reeducation critical for the success of this transfer have been identified and are discussed. Therapeutic IV. ..
  3. Ozkan T, Ozer K, Gulgonen A. Restoration of sensibility in irreparable ulnar and median nerve lesions with use of sensory nerve transfer: long-term follow-up of 20 cases. J Hand Surg Am. 2001;26:44-51 pubmed
    ..Based on these results we suggest that sensory nerve transfer is a simple and reliable way of restoring sensibility to the hand with favorably comparable results over conventional nerve grafting in selected cases...
  4. Bienek T, Kusz D, Cielinski L. Peripheral nerve compression neuropathy after fractures of the distal radius. J Hand Surg Br. 2006;31:256-60 pubmed
    ..No clinical signs of ulnar or radial nerve compression occurred in this study. ..
  5. Hess C, Guggenheim M, Schiller A, Altintas M, Giovanoli P, Calcagni M. [Fibrolipohamartoma of the upper extremity: treatment results in six patients over nine years]. Handchir Mikrochir Plast Chir. 2010;42:239-46 pubmed publisher
    ..It does, however, not have a beneficial effect on already present motor impairments, sensory deficits and cold sensitivity. We strictly advise against tumor resection. ..
  6. Park I, Lee Y, Kim H, Lee J, Roh Y, Park C, et al. Multiple etiologies of trigger wrist. J Plast Reconstr Aesthet Surg. 2016;69:335-40 pubmed publisher
    ..Mild-to-moderate symptoms of median neuropathy without thenar muscle atrophy were present in all patients...
  7. García Alvarez García F, García Alvarez García I, Castiella T, García Alvarez Alvarez F. [Forearm malignant epithelioid schwannoma associated with melanoma]. An Med Interna. 2003;20:195-7 pubmed
    ..One month later lung metastases appeared and the patient died. This case presented no known NF sign. However, a relationship must be searched for in the common origin of melanoma and schwannoma from the embryonic neural crest. ..
  8. Ostrovskiy D, Wilbourn A. Acute bowler's thumb. Neurology. 2004;63:938 pubmed
  9. Naddaf E, Dispenzieri A, Mandrekar J, Mauermann M. Clinical spectrum of Castleman disease-associated neuropathy. Neurology. 2016;87:2457-2462 pubmed
    ..neuropathy characterized by predominant sensory symptoms with no pain and mild distal sensory deficits (median Neuropathy Impairment Score of 7 points)...
  10. Kobayashi S, Baba H, Uchida K, Shimada S, Negoro K, Takeno K, et al. Localization and changes of intraneural inflammatory cytokines and inducible-nitric oxide induced by mechanical compression. J Orthop Res. 2005;23:771-8 pubmed
    ..Inflammatory cytokines and NO may be involved in intraneural inflammatory changes arising from mechanical compression. Such mediators may be of importance in the manifestation of neuropathy. ..
  11. Cartwright M, Donofrio P, Ybema K, Walker F. Detection of a brachial artery pseudoaneurysm using ultrasonography and EMG. Neurology. 2005;65:649 pubmed
  12. Duffy P, Schmandke A, Schmandke A, Sigworth J, Narumiya S, Cafferty W, et al. Rho-associated kinase II (ROCKII) limits axonal growth after trauma within the adult mouse spinal cord. J Neurosci. 2009;29:15266-76 pubmed publisher
    ..Together, these findings demonstrate that the ROCKII gene product limits axonal growth after CNS trauma. ..
  13. Chiang C, Tsai M, Chen C. MRI diagnosis of fibrolipomatous hamartoma of the median nerve and associated macrodystrophia lipomatosa. J Chin Med Assoc. 2010;73:499-502 pubmed publisher
    ..A similar skipped lesion at the median nerve of the middle forearm was also noted. To the best of our knowledge, this has not been reported in the English literature...
  14. Reyal Y, Robinson C, Salama A, Levy J. Neurological complications from brachial arteriovenous fistulae. Nephrol Dial Transplant. 2004;19:1923-4 pubmed
  15. Zerbi S, Cozzi G, Pedrini L. Median nerve dysfunction from anastomotic calcified aneurysm of a Cimino-Brescia fistula in a long-term dialysis patient. Nephrol Dial Transplant. 2006;21:3595-6 pubmed
  16. Audisio C, Nicolino S, Scevola A, Tos P, Geuna S, Battiston B, et al. ErbB receptors modulation in different types of peripheral nerve regeneration. Neuroreport. 2008;19:1605-9 pubmed publisher
    ..No significant changes in ErbB2 mRNA were detected. Our results suggest that ErbBs changes are involved in the molecular response to peripheral nerve injuries. ..
  17. Guney F, Yuruten B, Karalezli N. Digital neuropathy of the median and ulnar nerves caused by Dupuytren's contracture: Case report. Neurologist. 2009;15:217-9 pubmed publisher
    ..New studies are needed to provide better diagnostic criteria for the condition. ..
  18. Wigley R. Median nerve injury mimicking carpal tunnel syndrome. N Z Med J. 2002;115:25 pubmed
  19. Kwolek A, Zwolińska J. Immediate and long-term effects of selected physiotherapy methods in patients with carpal tunnel syndrome. Ortop Traumatol Rehabil. 2011;13:555-64 pubmed
    ..Ultrasound therapy combined with massage and kinesiotherapy brings the expected, long-term effects in patients with carpal tunnel syndrome. ..
  20. Rosén B, Chemnitz A, Weibull A, Andersson G, Dahlin L, Bjorkman A. Cerebral changes after injury to the median nerve: a long-term follow up. J Plast Surg Hand Surg. 2012;46:106-12 pubmed publisher
    ..Even though the clinical function improved over time it did not return to normal, and neither did the cortical response. ..
  21. Walia P, Erdemir A, Li Z. Subject-specific finite element analysis of the carpal tunnel cross-sectional to examine tunnel area changes in response to carpal arch loading. Clin Biomech (Bristol, Avon). 2017;42:25-30 pubmed publisher
    ..3mm2 (4% increase). The findings of the current study guide biomechanical manipulation to gain tunnel area increase, potentially helping reduce carpal tunnel pressure and relieve symptoms of compression median neuropathy.
  22. Bonel H, Heuck A, Frei K, Herrmann K, Scheidler J, Srivastav S, et al. Carpal tunnel syndrome: assessment by turbo spin echo, spin echo, and magnetization transfer imaging applied in a low-field MR system. J Comput Assist Tomogr. 2001;25:137-45 pubmed
    ..At low-field strength, median nerve edema is best depicted on T2-weighted TSE sequences, whereas MTC sequences are most sensitive to perineural contrast enhancement. ..
  23. Bilecenoglu B, Uz A, Karalezli N. Possible anatomic structures causing entrapment neuropathies of the median nerve: an anatomic study. Acta Orthop Belg. 2005;71:169-76 pubmed
    ..Knowledge of the course of the median nerve and its relations with the adjacent anatomic structures facilitates determination of the exact cause of entrapment and allows for a safe surgery. ..
  24. Nakamichi K, Tachibana S. Median nerve compression by a radially inserted palmaris longus tendon after release of the antebrachial fascia: A complication of carpal tunnel release. J Hand Surg Am. 2000;25:955-8 pubmed
    ..After decompression (detachment of the tendon) the patient had symptom relief. Release of the antebrachial fascia in the presence of this tendon variant carries a risk of median nerve compression by the tendon. ..
  25. Chen A, Robinson L. Electrodiagnosis as an extension of the physical examination: identifying proximal median neuropathy in the setting of carpal tunnel syndrome. Am J Phys Med Rehabil. 2008;87:862 pubmed publisher
  26. Yucel A, Yilmaz O, Babaoglu S, Acar M, Degirmenci B. Erratum to "Sonographic findings of the median nerve and prevalence of carpal tunnel syndrome in patients with Parkinson's disease" [Eur. J. Radiol. 67 (3) (2008) 546-550]. Eur J Radiol. 2008;68:499-502 pubmed
    ..Although sonography is not an ideal method of diagnosis for CTS, it may take our attention for indicating CTS in patients with PD especially in severe ones. ..
  27. Denys E, Lennon V. Asymptomatic Lambert-Eaton syndrome. Muscle Nerve. 2014;49:764-7 pubmed publisher
    ..It is plausible that patients with a subclinical syndrome would have abrupt neuromuscular decompensation when challenged with medications that compromise the safety factor for synaptic transmission. ..
  28. Ulrich D, Ulrich F, Schroeder M, Pallua N. Lipofibromatous hamartoma of the median nerve in patients with macrodactyly: diagnosis and treatment of a rare disease causing carpal tunnel syndrome. Arch Orthop Trauma Surg. 2009;129:1219-24 pubmed publisher
    ..Treatment should include decompression of the median nerve at points of compression, partial excision of the fibrofatty tissue, and debulking of soft tissue. In some cases, an epineurolysis can be additionally performed. ..
  29. Takahashi S, Chum M, Kimpinski K. Electrodiagnostic Characterization of Hereditary Neuropathy With Liability to Pressure Palsies. J Clin Neuromuscul Dis. 2017;18:119-124 pubmed publisher
    ..7%), distal median nerve at the wrist (84.4%), and fibular nerve at the fibular head (36.7%). Distal median neuropathy was associated with a mean terminal latency of 6.64 milliseconds...
  30. Noda Y, Sekiguchi K, Tokuoka H, Oda T, Hamaguchi H, Kanda F, et al. Ultrasonographic findings of proximal median neuropathy: A case series of suspected distal neuralgic amyotrophy. J Neurol Sci. 2017;377:1-5 pubmed publisher
    ..Our experience demonstrates that ultrasonography for proximal median neuropathy presenting as AIN palsy may be useful for the accurate lesion assessment.
  31. Bains R, Kotwal A, Saeed W. Recurrent carpal tunnel syndrome in a child due to fibrolipomatous hamartoma of the median nerve successfully treated by limited excision and decompression. J Plast Reconstr Aesthet Surg. 2006;59:1394-7 pubmed
    ..We present a case of recurrent carpal tunnel syndrome in a child caused by fibrolipomatous hamartoma of the median nerve which was successfully treated by limited excision of the fibrolipomatous tissue and decompression. ..
  32. Tsai P, Steinberg D. Median and radial nerve compression about the elbow. J Bone Joint Surg Am. 2008;90:420-8 pubmed
  33. Won H, Oh C, Chung I. A split and conjoined median nerve in the forearm. Anat Sci Int. 2010;85:115-7 pubmed publisher
    ..This variation of the median nerve has not been reported to our knowledge and may affect diagnosis and treatment of any neuropathy of the median nerve. ..
  34. Sammer D, Chung K. Tendon transfers: Part II. Transfers for ulnar nerve palsy and median nerve palsy. Plast Reconstr Surg. 2009;124:212e-21e pubmed publisher
    ..This article discusses the use of tendon transfer procedures for treatment of median and ulnar nerve palsy and combined nerve palsies. Postoperative management and potential complications are also discussed. ..
  35. Ganapathy K, Beine A, Ananth Reddy S. Early detection of impaired function of radial and high median nerves under field conditions. Indian J Lepr. 2004;76:361-3 pubmed
  36. Garayoa S, Romero Muñoz L, Pons Villanueva J. Acute compartment syndrome of the forearm caused by calcific tendinitis of the distal biceps. Musculoskelet Surg. 2010;94:137-9 pubmed publisher
    ..Muscular and bone lesions are the main causes of acute compartment syndromes. We report a case of acute compartment syndrome of the forearm caused by a calcific tendinitis of the distal biceps. ..
  37. Chou Y, Chen A, Chen C, Hsu Y, Wu C. Dorsal and volar 2.4-mm titanium locking plate fixation for AO type C3 dorsally comminuted distal radius fractures. J Hand Surg Am. 2011;36:974-81 pubmed publisher
    ..Therapeutic IV. ..
  38. Koehler S, Meier K, Lovy A, Fitzpatrick D, Kim J, Hausman M. Brachialis syndrome: a rare consequence of patient positioning causing postoperative median neuropathy. J Shoulder Elbow Surg. 2016;25:797-801 pubmed publisher
    ..Two patients with delayed decompression had poor neurologic outcomes. This supports modification of patient positioning, postoperative vigilance, and timely surgical management of brachialis syndrome. ..
  39. Lander L, Lou W, House R. Nerve conduction studies and current perception thresholds in workers assessed for hand-arm vibration syndrome. Occup Med (Lond). 2007;57:284-9 pubmed
    ..Quantitative sensory tests such as current perception measurement are insufficient for diagnostic purposes but may have a role in screening workers exposed to vibration. ..
  40. Mowery T, Sarin R, Elliott K, E Garraghty P. Nerve injury-induced changes in GABA(A) and GABA(B) sub-unit expression in area 3b and cuneate nucleus of adult squirrel monkeys: further evidence of developmental recapitulation. Brain Res. 2011;1415:63-75 pubmed publisher
  41. Hogaboom N, Diehl J, Oyster M, Koontz A, Boninger M. Ultrasonographic Median Nerve Changes After Repeated Wheelchair Transfers in Persons With Paraplegia: Relationship With Subject Characteristics and Transfer Skills. PM R. 2016;8:305-313 pubmed publisher
    ..susceptible to peripheral neuropathies from overuse, yet no studies have established a relationship between median neuropathy and wheelchair transfers...
  42. Perez Lopez C, Gutierrez M, Isla A. Inflammatory pseudotumor of the median nerve. Case report and review of the literature. J Neurosurg. 2001;95:124-8 pubmed
    ..The follow-up period has been 8 years. The cause of the lesion is unknown. The differential diagnosis includes benign and malignant peripheral nerve-sheath tumors, lymphoma, and all tumorlike lesions of peripheral nerves...
  43. Jaquet J, Luijsterburg A, Kalmijn S, Kuypers P, Hofman A, Hovius S. Median, ulnar, and combined median-ulnar nerve injuries: functional outcome and return to productivity. J Trauma. 2001;51:687-92 pubmed
    ..Forearm and wrist injuries are a common cause of morbidity and are often associated with suboptimal recovery of hand function. This study describes and compares outcome after median, ulnar, or combined median-ulnar nerve injuries...
  44. Stal M, Hagert C, Englund J. Pronator syndrome: a retrospective study of median nerve entrapment at the elbow in female machine milkers. J Agric Saf Health. 2004;10:247-56 pubmed
    ..In the non-surgical group, spontaneous improvement of the strength of FPL and FDP II was found in only four out of the 14 cases...
  45. Roganovic Z. Missile-caused median nerve injuries: results of 81 repairs. Surg Neurol. 2005;63:410-8; discussion 418-9 pubmed
    ..We present repair outcome for all median nerve injuries in which the median nerve was severed either by missile injury or secondarily in the subsequent resection of a neuroma in continuity...
  46. Anderson G. The surgical management of deformities of the hand in leprosy. J Bone Joint Surg Br. 2006;88:290-4 pubmed
  47. Chen J, Lue J, Lin L, Huang C, Chiang R, Chen C, et al. Effects of pre-emptive drug treatment on astrocyte activation in the cuneate nucleus following rat median nerve injury. Pain. 2010;148:158-66 pubmed publisher
    ..In conclusion, suppressing reactions to injury, such as the generation of ectopic discharges and activation of NMDA receptors, can decrease astrocyte activation in the CN and attenuate neuropathic pain sensations...
  48. Kamath J, Divyashree -, Harshvardhan -, Naik D, Bansal A. Three unusual factors contributing to compressive median neuropathy in the distal forearm in a single patient. J Plast Reconstr Aesthet Surg. 2012;65:e130-2 pubmed publisher
    ..This article reports a case in which three aetiological factors were present...
  49. Humphrey J, Dimascio L, Marchese M, Sinisi M. Late presentation of a partial median nerve palsy following a Gartland III supracondylar humeral fracture. Acta Orthop Belg. 2012;78:267-70 pubmed
    ..The case report highlights a late presentation of median nerve palsy following interposition of the neural structure within the reduced distal humeral fracture site; it shows that delayed surgery can be effective...
  50. Walker F, Cartwright M, Blocker J, Arcury T, Suk J, Chen H, et al. Prevalence of bifid median nerves and persistent median arteries and their association with carpal tunnel syndrome in a sample of Latino poultry processors and other manual workers. Muscle Nerve. 2013;48:539-44 pubmed publisher
    ..The prevalence of bifid median nerves and persistent median arteries, their co-occurrence, and their relationship to carpal tunnel syndrome (CTS) are only understood partially...
  51. Mak P, Irwin M, Tsui S. Functional improvement after physiotherapy with a continuous infusion of local anaesthetics in patients with complex regional pain syndrome. Acta Anaesthesiol Scand. 2003;47:94-7 pubmed
    ..We propose that this technique is a useful option for patients in all stages of complex regional pain syndrome where the emphasis is now directed toward functional improvement...
  52. Estirado de Cabo E, Posada de la Paz M, De Andrés Copa P, Plaza Cano M, García de Aguinaga M, Suarez Alvarez C, et al. Carpal tunnel syndrome. A new feature in the natural history of TOS?. Eur J Epidemiol. 2003;18:983-93 pubmed
  53. Soysal A, Atay T, Ozu T, Arpaci B. Electrophysiological evaluation of peripheral and autonomic involvement in leprosy. Can J Neurol Sci. 2004;31:357-62 pubmed
    ..Motor and sensory nerve conductions, F responses, sympathetic skin responses and R-R interval variations (RRIV) were studied to determine the type of peripheral neuropathy among patients with leprosy...
  54. Hsu C, Chen D, Chen H. Lipofibromatous hamartoma of the median nerve with long-term follow-up. Chang Gung Med J. 2005;28:111-6 pubmed
    ..There were no scars or trophic ulcers on fingertips at 3 years of follow-up regardless of the inadequate sensory return. Treatment of this benign tumor is still controversial. The relevant reports in the literature are reviewed...
  55. Battaglia T, Pannunzio M, Chhabra A. A carpometacarpal joint ganglion cyst causing median neuropathy. Am J Orthop (Belle Mead NJ). 2006;35:186-8 pubmed
  56. Bridgeman C, Naidu S, Kothari M. Clinical and electrophysiological presentation of pronator syndrome. Electromyogr Clin Neurophysiol. 2007;47:89-92 pubmed
    b>Median neuropathy at the elbow (pronator syndrome [PS]) is rare compared to compression at the wrist. We sought to evaluate the clinical/electrophysiological parameters of this focal neuropathy...
  57. Zanette G, Marani S, Tamburin S. Proximal pain in patients with carpal tunnel syndrome: a clinical-neurophysiological study. J Peripher Nerv Syst. 2007;12:91-7 pubmed
    ..PP may be found in a consistent number of CTS patients. PP may represent a clinical marker of mild median nerve damage. The presence of proximal complaints might be related to peripheral or central nervous system mechanisms...
  58. Lin S, Yeh J, Chen C, Chou S, Tsai Y. Effects of local lidocaine treatment before and after median nerve injury on mechanical hypersensitivity and microglia activation in rat cuneate nucleus. Eur J Pain. 2011;15:359-67 pubmed publisher
    ..High-concentration lidocaine was effective in decreasing microglia activation in the CN and in attenuating neuropathic pain sensations at the early stage following nerve injury, when microglia had not yet been activated...
  59. Keiner D, Tschabitscher M, Welschehold S, Oertel J. Anterior interosseous nerve compression syndrome: is there a role for endoscopy?. Acta Neurochir (Wien). 2011;153:2225-9 pubmed publisher
    ..Extended exploration of the anterior interosseous nerve is the surgical treatment of choice. The present study evaluates the feasibility of an endoscopic approach for nerve decompression...
  60. Ebenezer M, Kumar S, Partheebarajan S. Factors affecting functional outcome of opponens replacement in median nerve paralysis in leprosy. Indian J Lepr. 2012;84:131-6 pubmed
    ..3% fair and 10.1% poor results. Pinch strength, grip strength and fine manipulation showed improvement after surgery. Logistic regression analysis showed that duration of paralysis had a significant independent effect on the outcome...
  61. Spruijt L, Naviaux R, McGowan K, Nyhan W, Sheean G, Haas R, et al. Nerve conduction changes in patients with mitochondrial diseases treated with dichloroacetate. Muscle Nerve. 2001;24:916-24 pubmed
    ..Peripheral neuropathy appears to be a common side effect during chronic DCA treatment, even with coadministration of oral thiamine. Nerve conduction should be monitored during DCA treatment...
  62. Rehak D. Pronator syndrome. Clin Sports Med. 2001;20:531-40 pubmed
    ..When the correct diagnosis is made, pronator syndrome can be successfully treated nonoperatively or surgically, if necessary...
  63. Seror P, Leger J, Maisonobe T. Anterior interosseous nerve and multifocal motor neuropathy. Muscle Nerve. 2002;26:841-4 pubmed
    ..The efficacy of this treatment and the subsequent disclosure of conduction block in the right posterior interosseous and peroneal nerves definitively confirmed the multifocal motor neuropathy...
  64. Tuzuner S, Sherman G, Ozkaynak S, Ozcanli H. Endoscopic carpal tunnel release: modification of Menon's technique and data from 191 cases. Arthroscopy. 2004;20:721-7 pubmed
    ..The purpose of this study was to evaluate data from 227 hands of 191 patients who underwent releases with Menon's technique...
  65. Lorenzoni P, Lange M, Kay C, Silvado C, Scola R, Werneck L. [Fibrolipomatous hamartoma of the median nerve: case report]. Arq Neuropsiquiatr. 2005;63:881-4 pubmed
    ..The patient did not a have good response to clinical therapy, so he was submitted to a surgical decompression of the left carpal tunnel, and after three months of follow up is asymptomatic...
  66. Atherton D, Leong J, Anand P, Elliot D. Relocation of painful end neuromas and scarred nerves from the zone II territory of the hand. J Hand Surg Eur Vol. 2007;32:38-44 pubmed
  67. Gitkind A, Zhao P, Oh Park M, Fast A. Median palmar cutaneous nerve injury in a volleyball player. Am J Phys Med Rehabil. 2009;88:272-4 pubmed publisher
    ..To our knowledge, this is the first reported case of median palmar cutaneous nerve damage as a result of participation in competitive volleyball...
  68. Bovenzi M, Ronchese F, Mauro M. A longitudinal study of peripheral sensory function in vibration-exposed workers. Int Arch Occup Environ Health. 2011;84:325-34 pubmed publisher
    ..To investigate prospectively the relation between vibration-induced sensory dysfunction and measures of daily exposure to hand-transmitted vibration (HTV)...
  69. Rath S. Immediate active mobilization versus immobilization for opposition tendon transfer in the hand. J Hand Surg Am. 2006;31:754-9 pubmed
    ..To test the hypothesis that immediate postoperative active mobilization of the hand after opposition tendon transfer will achieve outcomes similar to those of the standard practice of cast immobilization...
  70. Stang F, Stutz N, Lanz U, van Schoonhoven J, Prommersberger K. [Results after revision surgery for carpal tunnel release]. Handchir Mikrochir Plast Chir. 2008;40:289-93 pubmed publisher
    ..The aim of this study was to assess the clinical results of revision surgery due to persistent neurological disturbances after carpal tunnel release...
  71. Donato G, Galasso O, Valentino P, Conforti F, Zuccala V, Russo E, et al. Pathological findings in subsynovial connective tissue in idiopathic carpal tunnel syndrome. Clin Neuropathol. 2009;28:129-35 pubmed
    ..Therefore, we believe that in the future a non-surgical management of carpal tunnel syndrome might be conjecturable via anti-VEGF drugs...
  72. McEntegart M, Dalzell J, Lindsay M. An unusual complication of transradial coronary angiography. J Invasive Cardiol. 2009;21:E91-2 pubmed
    ..The potential for serious complication should be borne in mind when deciding on the site of vascular access in such patients...
  73. Dang A, Rodner C. Unusual compression neuropathies of the forearm, part II: median nerve. J Hand Surg Am. 2009;34:1915-20 pubmed publisher
  74. Vital R, Illarramendi X, Antunes S, Nascimento M, da Costa Nery J, Nascimento O, et al. Isolated median neuropathy as the first symptom of leprosy. Muscle Nerve. 2013;48:179-84 pubmed publisher
    ..Focal peripheral neuropathy of the median nerve is mainly caused by a traumatic event or pressure, but it may also be produced by systemic illnesses. Among the latter, leprosy is a rare cause...
  75. Kaymak B, Ozcakar L, Cetin A, Erol K, Birsin Özçakar Z. Concomitant compression of median and ulnar nerves in a hemophiliac patient: a case report. Joint Bone Spine. 2002;69:611-3 pubmed
    ..His neurological examination revealed a pronounced median neuropathy and a minor ulnar neuropathy on the left side...
  76. Katsumi K, Ogose A, Hotta T, Hatano H, Kawashima H, Umezu H, et al. Plexiform schwannoma of the forearm. Skeletal Radiol. 2003;32:719-23 pubmed
    ..Pre-operative diagnosis of the rare plexiform schwannoma may be possible with careful imaging examination for the target sign...
  77. Lefebvre E, Bargoin R, Montagnon D. [Value of Color Doppler of bones and joints]. J Radiol. 2005;86:1879-91 pubmed
  78. Stütz N, Gohritz A, Novotny A, Falkenberg U, Lanz U, Van Schoonhoven J. Clinical and electrophysiological comparison of different methods of soft tissue coverage of the median nerve in recurrent carpal tunnel syndrome. Neurosurgery. 2008;62:194-9; discussion 199-200 pubmed publisher
  79. Tagliafico A, Pugliese F, Bianchi S, Bodner G, Padua L, Rubino M, et al. High-resolution sonography of the palmar cutaneous branch of the median nerve. AJR Am J Roentgenol. 2008;191:107-14 pubmed publisher
    ..The aim of this study was to describe the potential value of high-resolution sonography for evaluation of the palmar cutaneous branch of the median nerve (MN)...
  80. Ikemoto T, Tani T, Taniguchi S, Ikeuchi M, Kimura J. Effects of experimental focal compression on excitability of human median motor axons. Clin Neurophysiol. 2009;120:342-7 pubmed publisher
    ..To characterize the effect of focal compression by threshold tracking and other excitability measures of human median motor axons...
  81. Robinson A, Basheer M, Herbert K. An unusual cause of carpal tunnel syndrome. J Plast Reconstr Aesthet Surg. 2010;63:e788-91 pubmed publisher
    ..We advocate that all soft tissue swellings of the wrist with associated neurological signs be investigated appropriately, avoiding unnecessary additional surgery...
  82. Dy C, Lange D, Jones K, Garg R, DiCarlo E, Wolfe S. Diagnostic biopsy of the pronator teres and a motor branch of the median nerve: indications and technique. J Hand Surg Am. 2012;37:2570-5 pubmed publisher
    ..We describe a surgical technique and clinical series of biopsy of the pronator teres muscle and a motor branch of the median nerve...
  83. Rosén B, Lundborg G. Early use of artificial sensibility to improve sensory recovery after repair of the median and ulnar nerve. Scand J Plast Reconstr Surg Hand Surg. 2003;37:54-7 pubmed
    ..This case highlights the timing of sensory re-education after nerve repair and also emphasises the importance of early restitution of afferent inflow from a denervated hand during rehabilitation...
  84. Roy C, Nath N, Saha S. Reconstructive surgery in upper limbs in leprosy. J Indian Med Assoc. 2004;102:702-3 pubmed
    ..When ulnar nerve is part of much more extensive paralysis, reducing the availability of suitable motors, static mathods of conection of claw hand are done...
  85. Galtrey C, Fawcett J. Characterization of tests of functional recovery after median and ulnar nerve injury and repair in the rat forelimb. J Peripher Nerv Syst. 2007;12:11-27 pubmed
    ..The lesion model and functional tests that we have developed will be useful in testing therapeutic strategies for treating the consequences of inaccurate axon regeneration following peripheral nerve injury in humans...
  86. Nakatani Enomoto S, Bandoh M, Kita Y, Yamanouchi H, Enomoto H, Kimura T, et al. Paired stimulation study of the median nerve sensory action potential in diabetic patients. Acta Neurol Scand. 2008;118:94-8 pubmed publisher
    ..In order to detect subtle changes, we compared the conventional NCS with the relative refractory period (RRP) measurement of the median sensory nerve action potential by a paired stimulation method...
  87. McCormick C, Rath S, Patra P, Pereira J, Wilkinson M. A qualitative study of common functional problems experienced by people with complete ulnar nerve paralysis. Lepr Rev. 2008;79:154-61 pubmed
    ..To identify the most common functional problems caused by ulnar nerve palsy. This study is the first phase in the process of developing a patient-centred hand function questionnaire specific for ulnar palsy...
  88. Aberg M, Ljungberg C, Edin E, Millqvist H, Nordh E, Theorin A, et al. Clinical evaluation of a resorbable wrap-around implant as an alternative to nerve repair: a prospective, assessor-blinded, randomised clinical study of sensory, motor and functional recovery after peripheral nerve repair. J Plast Reconstr Aesthet Surg. 2009;62:1503-9 pubmed publisher
    ..This, however, should be confirmed by large-scale efficacy studies...
  89. Tubbs R, Marshall T, Loukas M, Shoja M, Cohen Gadol A. The sublime bridge: anatomy and implications in median nerve entrapment. J Neurosurg. 2010;113:110-2 pubmed publisher
    ..To the authors' knowledge, this structure and its relationship to the median nerve have not been studied. The aim of the present study was to quantitate this structure and elucidate its relationship to the median nerve...
  90. McClelland W, Means K. Palmaris profundus tendon prohibiting endoscopic carpal tunnel release: case report. J Hand Surg Am. 2012;37:695-8 pubmed publisher
    ..Given the volar position of the structure, its proximal point of insertion, and its minimal bulk, we did not feel that this was the cause of our patient's carpal tunnel syndrome...
  91. Tosi A, Orcioni G, Biase D, Costantini S, Ishikawa Y, Eusebi V. Synovial sarcoma involving the median nerve: a case report. Turk Patoloji Derg. 2012;28:266-9 pubmed publisher
    ..The differential diagnosis from similar tumors is discussed...
  92. Sinclair E, Andarawis Puri N, Ros S, Laudier D, Jepsen K, Hausman M. Relating applied strain to the type and severity of structural damage in the rat median nerve using second harmonic generation microscopy. Muscle Nerve. 2012;46:899-907 pubmed publisher
    ..Stretch injuries in peripheral nerves can cause pain, paralysis, and loss of sensation. Although optimal treatment depends on the degree of injury, it is difficult to determine the severity of induced nerve damage...