mydriasis

Summary

Summary: Dilation of pupils to greater than 6 mm combined with failure of the pupils to constrict when stimulated with light. This condition may occur due to injury of the pupillary fibers in the oculomotor nerve, in acute angle-closure glaucoma, and in ADIE SYNDROME.

Top Publications

  1. Sawada H, Yamakawa K, Yamakado H, Hosokawa R, Ohba M, Miyamoto K, et al. Cocaine and phenylephrine eye drop test for Parkinson disease. JAMA. 2005;293:932-4 pubmed
  2. Dulaurent T, Goulle F, Dulaurent A, Mentek M, Peiffer R, Isard P. Effect of mydriasis induced by topical instillations of 0.5% tropicamide on the anterior segment in normotensive dogs using ultrasound biomicroscopy. Vet Ophthalmol. 2012;15 Suppl 1:8-13 pubmed publisher
    To determine the effect of 0.5% tropicamide and the resultant mydriasis on the anterior segment in normotensive dogs using ultrasound biomicroscopy.
  3. Yu Y, Koss M. Studies of alpha-adrenoceptor antagonists on sympathetic mydriasis in rabbits. J Ocul Pharmacol Ther. 2003;19:255-63 pubmed
    This study was undertaken to identify the alpha-adrenergic receptor type responsible for sympathetically evoked mydriasis in pentobarbital-anesthetized rabbits...
  4. Aouba A, Der Agopian P, Genty Le Goff I, Mutschler C, Janin N, Patri B. [Pourfour du Petit syndrome: a rare aetiology of unilateral exophtalmos with mydriasis and lid retraction]. Rev Med Interne. 2003;24:261-5 pubmed
    ..Pourfour du Petit syndrome, rarely reported, is the opposite of Claude Bernard-Horner syndrome...
  5. Evans R, Jacobson D. Transient anisocoria in a migraineur. Headache. 2003;43:416-8 pubmed
  6. Sharma N, Ooi J, Papalkar D, Sharma S, Francis I, Fung V. Pharmacological mydriasis secondary to ipratropium bromide: a cause of unilateral dilated pupil. J Clin Neurosci. 2008;15:320-1 pubmed publisher
    Ipratropium bromide is a commonly used bronchodilator which has been rarely reported to cause pharmacological mydriasis. We report a 22-year-old woman using 6-hourly nebulised ipratropium from a multi-dose preparation, who presented with ..
  7. Balaguer Santamaria J, Escofet Soteras C, Chumbe Soto G, Escribano Subias J. [Episodic benign unilateral mydriasis. Clinical case in a girl]. Rev Neurol. 2000;31:743-5 pubmed
    ..Another cause of this sign is benign episodic unilateral mydriasis. This uncommon condition has been defined as an isolated benign cause of pupil asymmetry...
  8. Xu W, Gelber S, Orr Urtreger A, Armstrong D, Lewis R, Ou C, et al. Megacystis, mydriasis, and ion channel defect in mice lacking the alpha3 neuronal nicotinic acetylcholine receptor. Proc Natl Acad Sci U S A. 1999;96:5746-51 pubmed
    ..The phenotype in -/- mice may be similar to the rare human genetic disorder of megacystis-microcolon-intestinal hypoperistalsis syndrome...
  9. Potter D, Ogidigben M, Chu T. Lisuride acts at multiple sites to induce ocular hypotension and mydriasis. Pharmacology. 1998;57:249-60 pubmed
    ..In contrast to the unilateral effect on intraocular pressure, lisuride caused mydriasis in both eyes...

More Information

Publications97

  1. Hempel S, Senn P, Pakdaman F, Schmid M, Suppiger M, Schipper I. [Perioperative circulatory side effects of topical 5% phenylephrine for mydriasis]. Klin Monbl Augenheilkd. 1999;215:298-304 pubmed
    ..To study the systemic effects of topically applied 5% phenylephrine. To investigate intraoperative injection of epinephrine in the anterior chamber as an alternative...
  2. Lindberg K, Brunvand L. Congenital mydriasis combined with aneurysmal dilatation of a persistent ductus arteriosus Botalli: a rare syndrome. Acta Ophthalmol Scand. 2005;83:508-9 pubmed
    Abstract. A child with congenital mydriasis and aneurismal dilatation of persistent ductus arteriosus is described. We discuss congenital mydriasis as a separate entity and in combination with heart diseases.
  3. Yu Y, Koss M. Alpha2-adrenoceptors do not mediate reflex mydriasis in rabbits. J Ocul Pharmacol Ther. 2004;20:479-88 pubmed
    The aim of this study was to identify receptors that mediate reflex mydriasis in pentobarbital-anesthetized rabbits, in which the cervical sympathetic nerve was sectioned unilaterally...
  4. Bayramlar H, Miman M, Demirel S. Inferior oblique paresis, mydriasis, and accommodative palsy as temporary complications of sinus surgery. J Neuroophthalmol. 2004;24:225-7 pubmed
    A 15-year-old boy had temporary hypertropia, supraduction deficit, ipsilateral mydriasis, and accommodative paresis after bilateral endoscopic ethmoidectomy, bilateral partial inferior turbinectomy, septoplasty, and Caldwell-Luc ..
  5. Openshaw H. Unilateral mydriasis from ipratropium in transplant patients. Neurology. 2006;67:914 pubmed
  6. Nitta T, Kase M, Shinmei Y, Yoshida K, Chin S, Ohno S. Mydriasis with light-near dissociation in Fisher's Syndrome. Jpn J Ophthalmol. 2007;51:224-7 pubmed
    Approximately 50% of patients with Fisher's syndrome show involvement of the pupillomotor fibers and present with mydriasis and light-near dissociation...
  7. Narayanan M, Murphy M, Ainsworth J, Arul G. Mydriasis in association with MMIHS in a female infant: evidence for involvement of the neuronal nicotinic acetylcholine receptor. J Pediatr Surg. 2007;42:1288-90 pubmed
    ..a case of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS), occurring in association with mydriasis, in a female infant born to consanguineous Asian parents...
  8. Repéssé X, Geeraerts T, Pottecher J, Vigue B, Benhamou D, Duranteau J. [Coma with bilateral mydriasis after use of transdermal scopolamine in ICU]. Ann Fr Anesth Reanim. 2007;26:1070-2 pubmed
    ..with hydrocephalus requiring ventricular derivation, presenting a coma (Glasgow Coma Score=8) with bilateral mydriasis after the use of transdermal scopolamine (1 mg) for profuse bronchial secretions...
  9. Bond D, Vyas H, Venning H. Mydriasis due to self-administered inhaled ipratropium bromide. Eur J Pediatr. 2002;161:178 pubmed
    b>Mydriasis due to ipratropium bromide has previously been described in children and adults. Children as young as 4 years of age may attempt to self-administer their inhalers...
  10. Marešová K, Prochazkova J. [Cataract surgery without preoperative mydriasis]. Cesk Slov Oftalmol. 2009;65:16-8 pubmed
    Preoperative mydriasis is usually obtained by means of using combinations of sympatomimetics and parasympatolytics...
  11. Trinh K, Khac Q, Trinh L, Warrell D. Hyponatraemia, rhabdomyolysis, alterations in blood pressure and persistent mydriasis in patients envenomed by Malayan kraits (Bungarus candidus) in southern Viet Nam. Toxicon. 2010;56:1070-5 pubmed publisher
    ..niger in Bangladesh. These features of envenoming pose new problems for the management of krait bite cases in South east Asia and should stimulate a search for the causative venom toxins...
  12. Muttray A, Schneider M, Letzel S. Intoxication with a tropenol ester. Occup Med (Lond). 2012;62:305-7 pubmed publisher
    ..Shortly thereafter, he developed signs of anticholinergic intoxication with mydriasis, dry mouth, abnormal coordination and later sleepiness and seizures...
  13. Williams T, Williams A, Enzenauer R. Case report: unilateral mydriasis from topical Opcon-A and soft contact lens. Aviat Space Environ Med. 1997;68:1035-7 pubmed
    ..Continued emphasis of the possible deleterious side effects by the clinician is recommended to circumvent these problems. ..
  14. Fournié P, Ponchel C, Malecaze F, Arne J. Fixed dilated pupil (urrets-zavalia syndrome) and anterior subcapsular cataract formation after descemet stripping endothelial keratoplasty. Cornea. 2009;28:1184-6 pubmed publisher
    ..Based on these findings, a diagnosis of Urrets-Zavalia syndrome was made. To our knowledge, this is the first report of Urrets-Zavalia syndrome after DSAEK. ..
  15. Udy A. A 10-year-old child with status asthmaticus, hypercapnia and a unilateral dilated pupil. Paediatr Anaesth. 2005;15:1120-3 pubmed
  16. Hodder R. Woman with COPD and fixed and dilated pupil following head trauma. Chest. 2004;125:305-6 pubmed
  17. Pijls R, Hanssen H, Nuijts R, Koole L. Flexible coils with a drug-releasing hydrophilic coating: a new platform for controlled delivery of drugs to the eye?. Biomed Mater Eng. 2004;14:383-93 pubmed
    ..g., mydriasis (widening of the pupil) prior to corneal surgery. Studies with a new ocular drug delivery device are reported...
  18. Radian A, Grigoraş V, Mocanu C. [Mydriasis--areflexia syndrome in eye with posterior chamber intraocular lens]. Oftalmologia. 2006;50:91-3 pubmed
    ..In 25 eyes, at 2 to 7 month after surgery, we noticed a mydriasis with pupillary areflexia, though the majority (20 eyes) presented a miotic pupil in the days following surgery...
  19. Zanetti F, Fulco E, Chaves F, da Costa Pinto A, Arieta C, Lira R. Effect of preoperative use of topical prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery: a randomized trial. Indian J Ophthalmol. 2012;60:277-81 pubmed publisher
    ..prednisolone acetate, ketorolac tromethamine, nepafenac and placebo, on the maintenance of intraoperative mydriasis during cataract surgery. Randomized clinical trial...
  20. Huff J, Austin E. Neuro-Ophthalmology in Emergency Medicine. Emerg Med Clin North Am. 2016;34:967-986 pubmed publisher
    ..misdiagnosis of serious conditions, including carotid dissection (miosis) and aneurysmal third nerve palsy (mydriasis). Ptosis may be a sign of either Horner syndrome or third nerve palsy...
  21. Mitilian D, Charon B, Brunelle F, Di Rocco F. Removal of a chopstick out of the cavernous sinus, pons, and cerebellar vermis through the superior orbital fissure. Acta Neurochir (Wien). 2009;151:1295-7 pubmed publisher
    ..The foreign body was successfully pulled out in one piece surgically...
  22. Lopez Pison J, Pineda Ortiz I, Oteiza C, Loureiro B, Abenia P, Melendo J. [Survival with no sequelae after near-drowning with very poor signs for prognosis including persistent bilateral non-reactive mydriasis]. Rev Neurol. 1999;28:388-90 pubmed
    ..prolonged immersion time, coma, severe metabolic acidosis, hyperglycemia and persistent bilateral arreactive mydriasis. The beneficial effect of hypothermia is well known, and explains (at least partially) survival in cases of ..
  23. Rodriguez Barbon A, Cowen R, Knott C, Hughes K, Allinson K, Williams C, et al. Neoplasia in Three Aye-Ayes (Daubentonia madagascariensis). J Comp Pathol. 2018;159:16-20 pubmed publisher
    ..and immunohistochemical findings in one of the animals following initial presentation with bilateral mydriasis, absent pupillary reflex, head tilt and ataxia...
  24. Purvin V. Adie's tonic pupil secondary to migraine. J Neuroophthalmol. 1995;15:43-4 pubmed
    A 46-year-old woman observed transient unilateral mydriasis during a classic migraine attack. One week later she experienced a similar episode after which anisocoria was persistent...
  25. Prabhu S, Fox S, Mattke A, Armes J, Alphonso N. Extracorporeal Life Support in Multisystem Smooth Muscle Dysfunction Syndrome. World J Pediatr Congenit Heart Surg. 2016;: pubmed
    We describe an infant with congenital mydriasis, patent ductus arteriosus (PDA), pulmonary hypertension, and cystic lung disease. She had all the major components of multisystemic smooth muscle dysfunction syndrome...
  26. Holton L, Scott E, Nolan A, Reid J, Welsh E. Relationship between physiological factors and clinical pain in dogs scored using a numerical rating scale. J Small Anim Pract. 1998;39:469-74 pubmed
    ..These findings indicate that heart rate and respiratory rate are not useful indicators of pain in hospitalised dogs. It is also unlikely that pupil dilation will be a useful tool in the assessment of pain. ..
  27. Kampe S, Nori H, Schneider P, Krott R. [Mydriasis not reacting to light during an uneventful esophagectomy--drug-related side effect of Akrinor?]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2003;38:165-7 pubmed
    ..At the end of the procedure the anaesthetist diagnosed a mydriasis not reacting to light. The mydriasis lasted for 3 hours...
  28. Palmero J, Hollingsworth S, Kass P, Moore S, Pusterla N. Field use of N-butylscopolammonium bromide to facilitate thorough ophthalmic examination in horses. Vet J. 2016;211:104-5 pubmed publisher
    ..Horizontal and vertical pupil diameters, temperature, pulse, respiration, pupillary light reflexes (PLRs) and mydriasis sufficient to perform complete fundic examination were recorded. Tropicamide induced mydriasis in all horses...
  29. Sharma G, Deshmukh V, Albuquerque F, Wolf T, McDougall C. Resolution of mydriatic pupil after angioplasty and stenting of cervical internal carotid artery dissection: case report. Neurosurgery. 2009;64:E562-3; discussion E563 pubmed publisher
    ..Treatment with angioplasty and stenting of the dissected segment can restore flow and resolve the pupillary abnormality. A pathophysiological mechanism for the mydriasis is proposed.
  30. Richards J, Smith N, Moulin A. Unintentional Cannabis Ingestion in Children: A Systematic Review. J Pediatr. 2017;190:142-152 pubmed publisher
    ..Lethargy was the most common presenting sign (n?=?81, 71%) followed by ataxia (n?=?16, 14%). Tachycardia, mydriasis, and hypotonia were also commonly observed...
  31. Kitamura F, Inoue T, Kuroda U, Tanihara H. Angle closure caused by a plateau-like iris associated with an enlarged Soemmering's ring: a case report. BMC Ophthalmol. 2016;16:49 pubmed publisher
    ..After adding 2 % pilocarpine four times a day, the mydriasis resolved slightly, and the IOP decreased to the normal range between 8 and 18 mmHg...
  32. Yuzbasioglu E, Helvacioglu F, Sencan S. Fixed, dilated pupil after phakic intraocular lens implantation. J Cataract Refract Surg. 2006;32:174-6 pubmed
    ..Based on these findings, a diagnosis of Urrets-Zavalia syndrome was made. To our knowledge, this is the first report of Urrets-Zavalia syndrome after phakic IOL implantation. ..
  33. Hovanesian J, Sheppard J, Trattler W, Gayton J, Malhotra R, Schaaf D, et al. Intracameral phenylephrine and ketorolac during cataract surgery to maintain intraoperative mydriasis and reduce postoperative ocular pain: Integrated results from 2 pivotal phase 3 studies. J Cataract Refract Surg. 2015;41:2060-8 pubmed publisher
    To evaluate the efficacy and safety of phenylephrine 1.0%-ketorolac 0.3% (Omidria) for maintenance of mydriasis during, and reduction of ocular pain after, cataract surgery. Twenty centers in the United States and the Netherlands...
  34. Gee P, Schep L, Jensen B, Moore G, Barrington S. Case series: toxicity from 25B-NBOMe--a cluster of N-bomb cases. Clin Toxicol (Phila). 2016;54:141-6 pubmed publisher
    ..Hallucinations and violent agitation predominate along with serotonergic/stimulant signs such as mydriasis, tachycardia, hypertension and hyperthermia. The majority (7/10) required sedation with benzodiazepines...
  35. Tao J, Song Y, Zhang F, Sun M, Liu Y. [Characteristics of refractive status of mutant Lumican transgenic mice]. Zhonghua Yan Ke Za Zhi. 2015;51:527-31 pubmed
    ..One group (3-week-old) was randomly chosen and measured the refractive status by retinoscopy after mydriasis. Measurement of other groups were repeated the method above respectively in the fourth, fifth, sixth, eighth, ..
  36. Athanasiou A, Balogiannis I, Magras I. Lasting bilateral mydriasis after traumatic brain injury may not always be a lost case. Surg Neurol Int. 2017;8:229 pubmed publisher
    Lasting bilateral mydriasis and absence of pupillary light reflex following severe traumatic brain injury (TBI) are considered signs of irreversible brainstem damage and have been strongly associated with poor outcome.
  37. Yu Y, Koss M. Functional characterization of alpha-adrenoceptors mediating pupillary dilation in rats. Eur J Pharmacol. 2003;471:135-40 pubmed
    ..L-765314 (0.3-3 mg/kg, i.v.) was also ineffective in inhibiting the mydriasis evoked by cervical sympathetic nerve stimulation...
  38. Ibrahim M, Branson H, Buncic J, Shroff M. A case of Horner syndrome with intermittent mydriasis in a patient with hypoplasia of the internal carotid artery. AJNR Am J Neuroradiol. 2006;27:1318-20 pubmed
    ..to remain asymptomatic, we postulate that the enlarged posterior communicating artery (PcomA) in our patient caused mass effect on the cisternal segment of cranial nerve III causing intermittent mydriasis apart from Horner syndrome.
  39. Niknam S, Rajabi M. Fixed dilated pupil (urrets-zavalia syndrome) after deep anterior lamellar keratoplasty. Cornea. 2009;28:1187-90 pubmed publisher
    ..In these cases, the iris is fixed and dilated and adheres to anterior lens capsule. Prepupillary iris atrophy is usually seen and may be accompanied by a severe fibrinous reaction and anterior subcapsular lens opacity. ..
  40. Roos J. Episodic anisocoria and anxiety. Ophthalmology. 2008;115:1262-3 pubmed publisher
  41. Strnad M, Borovnik Lesjak V, Vujanović V, Križmarić M. Predictors of mortality in patients with isolated severe traumatic brain injury. Wien Klin Wochenschr. 2017;129:110-114 pubmed publisher
    ..040), ISS (p = 0.005) and mydriasis (p = 0.012). For predicting mortality, area under the curve (AUC) was calculated: for ISS 0...
  42. Stoller A, Dolder P, Bodmer M, Hammann F, Rentsch K, Exadaktylos A, et al. Mistaking 2C-P for 2C-B: What a Difference a Letter Makes. J Anal Toxicol. 2017;41:77-79 pubmed publisher
    ..We present a case of a 19-year-old male admitted to the emergency department with severe hallucinations, mydriasis, tachycardia, agitation and confusion following the use of a substance sold as 2C-B...
  43. Wang M, Zhao X, Wang X, Han C, Xing D, Wang C. Surgical Management of Aneurysmal Hematomas in the Presence of Brain Herniation on Arrival: A Single-Center Case Series Analysis. World Neurosurg. 2018;114:e468-e476 pubmed publisher
    ..3%). Significant factors related to death included bilateral mydriasis, lower initial Glasgow Coma Scale (GCS) score, larger hematoma volume, and no recovery of pupil reactivity after ..
  44. Saleh M. [Ocular trauma. Blunt ocular trauma]. J Fr Ophtalmol. 2012;35:445-53 pubmed publisher
    ..However, significant efforts are still needed, on the one hand, to assess and develop new therapies, and on the other hand, to implement effective policies to prevent ocular trauma. ..
  45. Jehle T, Puvanachandra N. [Ophthalmoplegia with bilateral mydriasis]. Ophthalmologe. 2012;109:76-8 pubmed publisher
    ..The suspected diagnosis of Miller-Fisher syndrome was confirmed by the detection of anti-ganglioside GQ1b antibodies. ..
  46. Hachemi M, Jourdan C, Convert J, Dailler F, Artru F. [Traumatic brain injury and asymmetry in pupillary size in severe head injury at the initial state: aetiology and value of the mydriasis]. Ann Fr Anesth Reanim. 2007;26:179-80 pubmed
  47. Hofer K, Grager B, Müller D, Rauber Lüthy C, Kupferschmidt H, Rentsch K, et al. Ketamine-like effects after recreational use of methoxetamine. Ann Emerg Med. 2012;60:97-9 pubmed publisher
    ..Observed signs and symptoms such as tachycardia, hypertension, confusion, agitation, stupor, ataxia, mydriasis, and nystagmus were consistent with ketamine-induced adverse effects and resolved with symptomatic treatment...
  48. Jastaneiah S, Al Towerki A, Al Assiri A. Fixed dilated pupil after penetrating keratoplasty for macular corneal dystrophy and keratoconus. Am J Ophthalmol. 2005;140:484-9 pubmed
    ..To identify predisposed eyes, risk factors, and protective measures and to evaluate methods of treatment for fixed dilated pupil after penetrating keratoplasty (PKP) for macular corneal dystrophy (MCD) and keratoconus...
  49. Chang Y. Residuals analysis of the generalized linear models for longitudinal data. Stat Med. 2000;19:1277-93 pubmed
    ..A non-parametric method, named the Wald-Wolfowitz run test, was proposed to check the residuals plots both quantitatively and graphically. The rationale proposedin this paper is well illustrated with two real clinical studies in Taiwan...
  50. Denion E, Petitbon J, Dalens P, Gerard M. [Eye anterior segment envenomation following a hymenopteran corneal sting]. J Fr Ophtalmol. 2007;30:108-9 pubmed
  51. Richardson S, Edwards K. Accidental acute clidinium toxicity. Emerg Med J. 2009;26:460 pubmed publisher
    ..Emergency physicians should be aware of the potential for antimuscarinic toxicity in patients using illicit chlordiazepoxide...
  52. Sridhar M, Raber I. Open-sky pupilloplasty during phakic penetrating keratoplasty to treat a fixed, dilated pupil. J Cataract Refract Surg. 2002;28:404-6 pubmed
    ..Postoperatively, the pupil was relatively round with a diameter of approximately 4.0 mm, the cosmetic result was favorable, the photophobia had resolved, and the lens and corneal transplant were clear...
  53. Schmitt J, Riedel W, Vuurman E, Kruizinga M, Ramaekers J. Modulation of the critical flicker fusion effects of serotonin reuptake inhibitors by concomitant pupillary changes. Psychopharmacology (Berl). 2002;160:381-6 pubmed
    ..However, such an interpretation may be questioned since CFF elevations may also be due to SSRI-induced increases in pupil diameter...
  54. Nimeskern N, Orenstein D, Ous W, Hattenberger P. [A surprising calvarial sample]. Rev Stomatol Chir Maxillofac. 2006;107:119-20 pubmed
  55. Ashker L, Weinstein J, Dias M, Kanev P, Nguyen D, Bonsall D. Arachnoid cyst causing third cranial nerve palsy manifesting as isolated internal ophthalmoplegia and iris cholinergic supersensitivity. J Neuroophthalmol. 2008;28:192-7 pubmed publisher
    ..Our patient serves as a reminder that isolated internal ophthalmoplegia with cholinergic supersensitivity is compatible with a preganglionic compressive third nerve lesion, particularly in a young child...
  56. Ortega Carnicer J, Ambrós A, Diarte J. Reversible posterior leukoencephalopathy syndrome in a young trauma patient. Resuscitation. 2005;64:119-20 pubmed
  57. Carrillo Esper R, Limón Camacho L, Vallejo Mora H, Contreras Domínguez V, Hernández Aguilar C, Carvajal Ramos R, et al. [Non-hypothermic J wave in subarachnoid hemorrhage]. Cir Cir. 2004;72:125-9 pubmed
    ..Non-hypothermic J wave is an infrequent electrocardiographic manifestation of subarachnoid hemorrhage. We describe a clinical case of non-hypothermic J wave in a patient with subarachnoid hemorrhage...
  58. Pritz M. Contralateral pupillary dilatation after intracisternal papaverine instillation. Surg Neurol. 2007;67:546 pubmed
  59. He D, Blomquist P, Ellis E. Association between ocular injuries and internal orbital fractures. J Oral Maxillofac Surg. 2007;65:713-20 pubmed
    ..This study was performed to assess the association between orbital blowout fractures and ocular injuries...
  60. Ahn J, Jeong M, Lee E, Kim S, Park S, Park S, et al. Effects of peribulbar anesthesia (sub-Tenon injection of a local anesthetic) on akinesia of extraocular muscles, mydriasis, and intraoperative and postoperative analgesia in dogs undergoing phacoemulsification. Am J Vet Res. 2013;74:1126-32 pubmed publisher
    To evaluate the effects of peribulbar anesthesia (sub-Tenon injection of lidocaine hydrochloride) on akinesia of extraocular muscles, mydriasis, and intraoperative and postoperative analgesia in dogs undergoing phacoemulsification.
  61. Carrascosa Romero M, Ruiz Cano R, Martinez Lopez F, Alfaro Ponce B, Perez Pardo A. [Congenital mydriasis as an initial sign of septo-optic dysplasia]. Arch Soc Esp Oftalmol. 2013;88:398-402 pubmed publisher
    ..We discuss thedifferential diagnosis of congenital mydriasis.
  62. Pfeiffer N, Grehn F, Wellek S, Schwenn O. Intraocular thymoxamine or acetylcholine for the reversal of mydriasis. Ger J Ophthalmol. 1994;3:422-6 pubmed
    ..02% or acetylcholine 1.0% or thymoxamine 0.01% plus acetylcholine 0.5% were used intraocularly to reverse mydriasis during cataract surgery. Prior to surgery, pupils were dilated with scopolamine 0...
  63. Minasian M, Ayliffe W. Fixed dilated pupil following deep lamellar keratoplasty (Urrets-Zavalia syndrome). Br J Ophthalmol. 2002;86:115-6 pubmed
  64. Grahn B, Cullen C. Diagnosis of blindness in a horse. Can Vet J. 2002;43:563-4 pubmed
  65. Oh S, Shin B, Lee Y, Lee A, Kim J. Benztropine-induced Esotropia and Mydriasis. J Neuroophthalmol. 2007;27:312-3 pubmed
  66. Ema M, Fujii S, Matsumoto M, Hirose A, Kamata E. Prenatal developmental toxicity study of the basic rubber accelerator, 1,3-di-o-tolylguanidine, in rats. Reprod Toxicol. 2006;22:672-8 pubmed
    ..At 40 mg/kg bw/day, deaths were observed in four out of 24 females. The incidences of females showing mydriasis at 20 and 40 mg/kg bw/day and showing decreased locomotor activity at 40 mg/kg bw/day were significantly ..
  67. Salim S, Childers K, Lupinacci A, HU G, Zemon V, Netland P. Influence of pupil size and other test variables on visual function assessment using visual evoked potentials in normal subjects. Doc Ophthalmol. 2010;121:1-7 pubmed publisher
    ..When obtaining icVEP measurements, the influence of pupil size and optical blur should be kept in mind for accurate interpretations...
  68. Aron J, Chatterjee D. Transient Pourfour du Petit syndrome. Anesth Analg. 2007;104:1616 pubmed
  69. Brown C, MacKinnon A, Redfern W, Hicks P, Kilpatrick A, Small C, et al. The pharmacology of RS-15385-197, a potent and selective alpha 2-adrenoceptor antagonist. Br J Pharmacol. 1993;108:516-25 pubmed
    ..38). 6. In anaesthetized rats, RS-15385-197 was a potent antagonist of the mydriasis response induced by UK-14,304 or clonidine (AD50 5 and 7 microg kg-1, i.v., respectively; 96 microg kg-1, p.o...
  70. Berney C, Wolfensberger T. [Mydriasis induced by splinter from belladonna bush]. Klin Monbl Augenheilkd. 2000;216:346-7 pubmed
    ..Pupillary dilatation with alcaloids from the Atropa belladonna plant have been used since antiquity. It is less known that the wood of the plant contains an even higher concentration of alkaloids than the ripe fruit...
  71. Berger I, Steinberg A, Schlesinger Y, Seelenfreund M, Schimmel M. Neonatal mydriasis: intravenous lidocaine adverse reaction. J Child Neurol. 2002;17:400-1 pubmed
    ..We present a neonate with a seizure disorder who acutely developed pupillary mydriasis secondary to lidocaine overdose...
  72. Kara M, Dikmen E, Akarsu C, Birol A. Unilateral hyperhydrosis in Pourfour du Petit syndrome. Eur J Cardiothorac Surg. 2004;26:456-8 pubmed
    ..The patients presented with right-sided mydriasis and ipsilateral hemifacial hyperhydrosis. The onset of disease was followed by a trauma in both patients...
  73. Hirowatari T, Tokuda K, Kamei Y, Miyazaki Y, Matsubara M. Evaluation of a new preoperative ophthalmic solution. Can J Ophthalmol. 2005;40:58-62 pubmed
    Maximum mydriasis and corneal clarity during intraocular surgery are important to ensure operational safety...
  74. Li G, Polomeno R. Congenital mydriasis: spontaneous resolution in one of two cases. Can J Ophthalmol. 2005;40:204-7 pubmed
  75. Young C, Simons K, Jacobs B. Traumatic mydriasis: "cat's eye" in a football player. Clin J Sport Med. 2006;16:179-80 pubmed
  76. Gerber R, Naude T, De Kock S. Confirmed Datura poisoning in a horse most probably due to D. ferox in contaminated tef hay. J S Afr Vet Assoc. 2006;77:86-9 pubmed
    ..This horse exhibited marked mydriasis on the first 2 days of being poisoned and showed protracted, milder mydriasis for a further 7 days...
  77. Altas M, Serefhan A, Silav G, Cerci A, Coskun K, Elmaci I. Diagnosis and management of pituitary abscess: a case series and review of the literature. Turk Neurosurg. 2013;23:611-6 pubmed publisher
    ..This paper aims to discuss four cases of preoperatively diagnosed pituitary abscess in the light of the literature...
  78. Valenca M, Andrade Valença L, Martins C, de Fátima Vasco Aragão M, Batista L, Peres M, et al. Cluster headache and intracranial aneurysm. J Headache Pain. 2007;8:277-82 pubmed
    ..These findings strongly suggest a pathophysiological link between the two conditions. The authors discuss the potential pathophysiological mechanisms underlying cluster-like headache due to intracranial carotid artery aneurysm...
  79. Czyz C, Bacon T, Petrie T, Justice J, Cahill K. Isolated, complete paralytic mydriasis secondary to herpes zoster ophthalmicus. Pract Neurol. 2013;13:183-4 pubmed publisher
    ..The presentation of complete paralytic mydriasis as the sole cranial nerve complication following herpes zoster ophthalmicus infection is a rare finding...
  80. Sobreira I, Sousa C, Raposo A, Fagundes F, Dias A. Ophthalmoplegic migraine with persistent dilated pupil. J Child Neurol. 2013;28:275-6 pubmed publisher
    ..Since the diagnosis, she has exhibited a persistent right-eye mydriasis, despite resolution of migrainous episodes...
  81. Figueiredo G, Kolli S, Ahmad S, Gales K, Figueiredo F. Urrets-Zavalia syndrome following penetrating keratoplasty for keratoconus. Graefes Arch Clin Exp Ophthalmol. 2013;251:809-15 pubmed publisher
    ..It is a poorly understood complication following penetrating keratoplasty (PKP) for keratoconus (KC). In this work, we aim to establish the incidence, visual outcomes, and an understanding of UZS...
  82. Chelnis J, Sieminski S, Reynolds J. Urrets-Zavalia syndrome following goniotomy in a child. J AAPOS. 2012;16:312-3 pubmed publisher
    ..After 2 years of follow-up, the pupil remained fixed and dilated in that eye. To our knowledge this is the first case of Urrets-Zavalia syndrome to be reported following goniotomy and the first to occur in a child...
  83. McDermott A. Unilateral mydriasis potentially associated with contact with a supplement powder mix. Mil Med. 2012;177:359-60 pubmed
    Dietary supplement use is common in military populations. Presented is a case of unilateral mydriasis from contact with a supplement mix. Standardized approach to mydriasis is fundamental for diagnosis.
  84. Aguirre Balsalobre F, González Herrera M, Mengual Verdú E, García Conca V, Hueso Abancens J. [Simultaneous botulism in two brothers addicted to cocaine]. Arch Soc Esp Oftalmol. 2007;82:583-6 pubmed
    ..Botulism is currently an uncommon disease in which the botulinum toxin causes a progressive muscular paralysis that can lead to the death due to a failure of respiratory muscles...
  85. Braksick S, Wijdicks E. Moisture and mydriasis. Pract Neurol. 2014;14:187-8 pubmed publisher
  86. Ajay K, Saranya S, Sundaresh D, Hithashree H, Hemalatha B, Krishnaswamy M, et al. Efficacy and safety of intraoperative intracameral mydriasis in manual small incision cataract surgery - A randomized controlled trial. Indian J Ophthalmol. 2017;65:584-588 pubmed publisher
    ..To assess the sustainability of intracameral mydriasis in MSICS by monitoring pupil size at specific junctures during the surgery.
  87. Pérez Flores M, Velasco Casares M, Lorenzo Carrero J. [Painful incomplete third-nerve palsy caused by an internal carotid-communicating posterior artery aneurysm]. Arch Soc Esp Oftalmol. 2009;84:43-6 pubmed
    ..We describe the differential diagnosis with Tolosa-Hunt syndrome and the results after endovascular treatment...
  88. Niyadurupola N, Broadway D. Pigment dispersion syndrome and pigmentary glaucoma--a major review. Clin Exp Ophthalmol. 2008;36:868-82 pubmed publisher
    ..Peripheral laser iridotomy can reverse backward bowing of the iris and may prevent progression of pigmentary glaucoma...