Summary: Mild to moderate loss of bilateral lower extremity motor function, which may be a manifestation of SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; MUSCULAR DISEASES; INTRACRANIAL HYPERTENSION; parasagittal brain lesions; and other conditions.

Top Publications

  1. Ak H, Ulu M, Sar M, Albayram S, Aydin S, Uzan M. Adult intramedullary mature teratoma of the spinal cord: review of the literature illustrated with an unusual example. Acta Neurochir (Wien). 2006;148:663-9; discussion 669 pubmed
    ..An illustrative case of an extremely unusual localization is also presented. ..
  2. Lourbopoulos A, Ioannidis P, Balogiannis I, Stavrinou P, Koletsa T, Karacostas D. Cervical epidural plasmacytoma presenting as ascending paraparesis. Spine J. 2011;11:e1-4 pubmed publisher
    ..Spinal epidural plasmacytomas are very rare and are usually localized in the cervicothoracic and lumbar spines...
  3. Dalvie S, Skinner J, Vellodi A, Noorden M. Mobile thoracolumbar gibbus in Morquio type A: the cause of paraparesis and its management. J Pediatr Orthop B. 2001;10:328-30 pubmed
    ..All patients recovered neurologically after anterior decompression and correction of kyphosis. We believe that the cause of cord dysfunction is mobility at the kyphus and compression by the bulging discs and the internal gibbus...
  4. Panagiotopoulos V, Konstantinou D, Solomou E, Panagiotopoulos E, Marangos M, Maraziotis T. Extended cervicolumbar spinal epidural abscess associated with paraparesis successfully decompressed using a minimally invasive technique. Spine (Phila Pa 1976). 2004;29:E300-3 pubmed
    ..A case of a multisegmental, cervicothoracolumbar epidural abscess, in an 80-year-old man, successfully decompressed by using a minimally invasive technique, is presented...
  5. Sakaura H, Hosono N, Mukai Y, Fujii R, Yoshikawa H. Paraparesis due to exacerbation of preexisting spinal pseudoarthrosis following infliximab therapy for advanced ankylosing spondylitis. Spine J. 2006;6:325-9 pubmed
    ..The most important adverse effects of infliximab are infections, malignancies, autoimmunities, and hypersensitivity reactions. There has never been a reported case of paraparesis after infliximab therapy for AS.
  6. Zanolari P, Konar M, Tomek A, Hoby S, Meylan M. Paraparesis in an adult alpaca with discospondylitis. J Vet Intern Med. 2006;20:1256-60 pubmed
  7. Tong T, Simpson D. Case report: Spinal dermoid sinus in a Burmese cat with paraparesis. Aust Vet J. 2009;87:450-4 pubmed publisher
    ..The cat recovered hindlimb function after surgery and remains asymptomatic 50 months after surgery except for a persistent inability to urinate voluntarily...
  8. Mellgren G, Bleskestad I, Aanderud S, Bindoff L. Thyrotoxicosis and paraparesis in a young woman: case report and review of the literature. Thyroid. 2002;12:77-80 pubmed
    ..With increasing immigration, TPP is likely to occur more frequently in both Europe and North America and awareness of the condition is vital. Treatment of the underlying thyroid dysfunction cures the muscle symptoms...
  9. Diaz J. Permanent paraparesis and cauda equina syndrome after epidural blood patch for postdural puncture headache. Anesthesiology. 2002;96:1515-7 pubmed

More Information

Publications149 found, 100 shown here

  1. Schmidt Hieber M, Thiel E, Keilholz U. Spinal paraparesis due to leukemic meningitis in early-stage chronic lymphocytic leukemia. Leuk Lymphoma. 2005;46:619-21 pubmed
    ..The stage called for a "watch and wait" strategy. Six months later the patient presented with paraparesis. Magnetic resonance imaging of the lumbar spine revealed no abnormalities...
  2. Beguiristain J, del Rio J, Duart J, Barroso J, Silva A, Villas C. Corrosion and late infection causing delayed paraparesis after spinal instrumentation. J Pediatr Orthop B. 2006;15:320-3 pubmed
    ..She presented progressive paraparesis during the last 2 months...
  3. Jenny B, Radovanovic I, Haenggeli C, Delavelle J, Rufenacht D, Kaelin A, et al. Association of multiple vertebral hemangiomas and severe paraparesis in a patient with a PTEN hamartoma tumor syndrome. Case report. J Neurosurg. 2007;107:307-13 pubmed
    ..The patient presented in the pediatric emergency department with severe spastic paraparesis. A magnetic resonance imaging study of the spine showed vertebral hemangiomas at multiple levels, but stenosis ..
  4. Mannoji C, Yamazaki M, Kamegaya M, Saisu T, Minami S, Takahashi K. Paraparesis caused by rib exostosis in a child with Down syndrome: a case report. Spine (Phila Pa 1976). 2008;33:E911-3 pubmed publisher
    ..Case report...
  5. Kusama Eguchi K, Yamazaki Y, Ueda T, Suda A, Hirayama Y, Ikegami F, et al. Hind-limb paraparesis in a rat model for neurolathyrism associated with apoptosis and an impaired vascular endothelial growth factor system in the spinal cord. J Comp Neurol. 2010;518:928-42 pubmed publisher
    Neurolathyrism is a motor neuron disease characterized by lower limb paraparesis. It is associated with ingestion of a plant excitotoxin, beta-N-oxalyl-L-alphabeta-diaminopropionic acid (L-beta-ODAP), an agonist of alpha-amino-3-hydroxy-..
  6. Rockman C, Riles T, Landis R. Lower extremity paraparesis or paraplegia subsequent to endovascular management of abdominal aortic aneurysms. J Vasc Surg. 2001;33:178-80 pubmed
    Lower extremity paraplegia or paraparesis is an extremely rare event after operative repair of infrarenal abdominal aortic aneurysms (AAAS)...
  7. Heuer G, Stiefel M, Bailey R, Schuster J. Acute paraparesis from hemorrhagic spinal ependymoma: diagnostic dilemma and surgical management. Report of two cases and review of the literature. J Neurosurg Spine. 2007;7:652-5 pubmed
    ..These cases illustrate the rare but clinically significant incidence of acute neurological decline caused by hemorrhagic cauda equina ependymomas, including the potential for delayed diagnosis and treatment...
  8. Aliberti B, Patrikiou A, Terentiou A, Frangatou S, Papadimitriou A. Spinal cord compression due to extramedullary haematopoiesis in two patients with thalassaemia: complete regression with blood transfusion therapy. J Neurol. 2001;248:18-22 pubmed
    ..We present two patients suffering from thalassaemia (intermedia and beta homozygous) and paraparesis due to spinal cord compression from intrathoracic extramedullary haematopoietic masses...
  9. van Lindert E, Bartels R, Noordam K. Spinal stenosis with paraparesis in albright hereditary osteodystrophy. Case report and review of the literature. Pediatr Neurosurg. 2008;44:337-40 pubmed publisher
    ..The pathological changes of the skin also dissolved. Ten more cases of myelopathy and paraparesis in association with AHO, of whom two were children, could be found in the literature...
  10. Huntoon M, Martin D. Paralysis after transforaminal epidural injection and previous spinal surgery. Reg Anesth Pain Med. 2004;29:494-5 pubmed
    ..More than 4 years later, the patient continues to be troubled by persistent paraparesis and chronic pain...
  11. Ruitenberg A, Vecht C, van den Bent M, Taal W. [Clinical reasoning and decision-making in practice. An older man with prostate carcinoma and a painless paraparesis of the legs]. Ned Tijdschr Geneeskd. 2005;149:1785-90 pubmed
    A 78-year-old man with metastasised prostate carcinoma presented with a painless paraparesis. His cerebrospinal fluid showed elevated protein and a mononuclear pleiocytosis, but cytology investigations of 5 separate samples revealed no ..
  12. Estrera A, Miller C, Chen E, Meada R, Torres R, Porat E, et al. Descending thoracic aortic aneurysm repair: 12-year experience using distal aortic perfusion and cerebrospinal fluid drainage. Ann Thorac Surg. 2005;80:1290-6; discussion 1296 pubmed
    ..The purpose of this report is to analyze our experience with regard to neurologic deficit (paraplegia and paraparesis) and mortality using the adjuncts of distal aortic perfusion and cerebrospinal fluid drainage...
  13. Coler Reilly A, Sato T, Matsuzaki T, Nakagawa M, Niino M, Nagai M, et al. Effectiveness of Daily Prednisolone to Slow Progression of Human T-Lymphotropic Virus Type 1-Associated Myelopathy/Tropical Spastic Paraparesis: A Multicenter Retrospective Cohort Study. Neurotherapeutics. 2017;14:1084-1094 pubmed publisher
    ..the progressive neurodegenerative disease HTLV-1-associated myelopathy (HAM), also known as tropical spastic paraparesis (TSP), which is characterized by chronic spinal cord inflammation and accompanying myelopathic symptoms...
  14. Nakamura S, Kakinohana M, Taira Y, Iha H, Sugahara K. The effect of gamma-aminobutyric acid (GABA) receptor drugs on morphine-induced spastic paraparesis after a noninjurious interval of spinal cord ischemia in rats. Anesth Analg. 2002;95:1389-95, table of contents pubmed
    ..that intrathecal morphine given after a noninjurious interval of spinal cord ischemia induced transient spastic paraparesis in a rodent model. However, the mechanism of this paraparesis is unknown...
  15. Babu A, Babu L, Raden M, Ahuja K. Transient paraparesis due to right carotid stenosis with left anterior cerebral artery aplasia. Neurology. 2006;67:907 pubmed
  16. Zipfel B, Czerny M, Funovics M, Coppi G, Ferro C, Rousseau H, et al. Endovascular treatment of patients with types A and B thoracic aortic dissection using Relay thoracic stent-grafts: results from the RESTORE Patient Registry. J Endovasc Ther. 2011;18:131-43 pubmed publisher
    ..Paraplegia, paraparesis, and stroke occurred in 4, 1, and 2 patients, respectively; 2 cases of paraplegia occurred in patients with ..
  17. García Sánchez S, Gómez Galindo M, Guzmán Pantoja J. [Botulinum toxin A and physical therapy in gait in cerebral palsy]. Rev Med Inst Mex Seguro Soc. 2017;55:18-24 pubmed increase the arches of mobility and functionality of the gait of patients with hemiparesis and spastic paraparesis. Introducción: La parálisis cerebral (PCI) es la principal causa de discapacidad en la infancia...
  18. Schatz M, Tong P, Beaumelle B. Unconventional secretion of viral proteins. Semin Cell Dev Biol. 2018;83:8-11 pubmed publisher
    ..Several studies indicated that circulating retroviral transactivating proteins Tat and Tax are involved in the development of AIDS and HTLV-I associated myelopathy/tropical spastic paraparesis, respectively.
  19. Gazulla Abio J, Benavente Aguilar I. [Paraparesis, hyperprolactinemia and adynamic ileus in Guillain-Barré syndrome]. Neurologia. 2004;19:396-400 pubmed its onset, that consisted of constipation and hypertension, followed by adynamic ileus and flaccid paraparesis with areflexia limited to the lower limbs, is presented...
  20. Ravnik J, Potrc S, Kavalar R, Ravnik M, Zakotnik B, Bunc G. Dumbbell synovial sarcoma of the thoracolumbar spine: a case report. Spine (Phila Pa 1976). 2009;34:E363-6 pubmed publisher
    ..A case report is of a giant dumbbell-shaped synovial sarcoma of the thoracolumbar spine is presented...
  21. Ohba T, Ebata S, Clinton D, Koyama K, Haro H. Instability of treated vertebrae after balloon kyphoplasty causing paraparesis in osteoporotic vertebral compression fracture: a report of two cases. Eur Spine J. 2013;22 Suppl 3:S341-5 pubmed publisher
    ..with balloon kyphoplasty (BKP) that were complicated by spinal instability and resultant lower extremity paraparesis. Kyphoplasty was performed in two patients with OVCF that had persistent back pain despite a course of ..
  22. Szymocha R, Akaoka H, Dutuit M, Malcus C, Didier Bazes M, Belin M, et al. Human T-cell lymphotropic virus type 1-infected T lymphocytes impair catabolism and uptake of glutamate by astrocytes via Tax-1 and tumor necrosis factor alpha. J Virol. 2000;74:6433-41 pubmed
    ..virus type 1 (HTLV-1) is the causative agent of a chronic progressive myelopathy called tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP/HAM)...
  23. Windpassinger C, Auer Grumbach M, Irobi J, Patel H, Petek E, Hörl G, et al. Heterozygous missense mutations in BSCL2 are associated with distal hereditary motor neuropathy and Silver syndrome. Nat Genet. 2004;36:271-6 pubmed
    ..Silver syndrome (OMIM #270685) is a rare form of hereditary spastic paraparesis mapped to chromosome 11q12-q14 (SPG17) in which spasticity of the legs is accompanied by amyotrophy of the ..
  24. Hsing J, Welgampola M, Kiernan M. Reversible myeloradiculopathy due to Mycoplasma pneumoniae. J Clin Neurosci. 2007;14:61-4 pubmed
    A 22-year-old man presented with flaccid paraparesis and a thoracic sensory level in the context of a recent respiratory illness...
  25. Zagami A, Granot R. Non-Hodgkin's lymphoma involving the cauda equina and ocular cranial nerves: case reports and literature review. J Clin Neurosci. 2003;10:696-9 pubmed
    ..Differential diagnoses and treatment options for NHL involving the cauda equina are also discussed. ..
  26. Grenader T, Shavit L. Synchronous male breast cancer and carcinoma of prostate in 90-year-old male, presented with spinal cord compression and multiple spine lytic lesions. Breast J. 2007;13:410-2 pubmed
    ..6%. A histological examination of a specimen from a lytic lesion of the spine was consistent with metastatic breast cancer and a needle biopsy of the prostate showed adenocarcinoma, Gleason score 3 + 4. ..
  27. Joshi T, Yamazaki M, Zhao H, Becker D. Spinal schistosomiasis: differential diagnosis for acute paraparesis in a U.S. resident. J Spinal Cord Med. 2010;33:256-60 pubmed
    ..To present a case of a US resident who developed acute paraparesis due to spinal schistosomiasis after traveling to sub-Saharan Africa...
  28. Edvardson S, Kose S, Jalas C, Fattal Valevski A, Watanabe A, Ogawa Y, et al. Leukoencephalopathy and early death associated with an Ashkenazi-Jewish founder mutation in the Hikeshi gene. J Med Genet. 2016;53:132-7 pubmed publisher
    ..The genetic basis of a novel congenital leukodystrophy, associated with early onset spastic paraparesis, acquired microcephaly and optic atrophy was studied in six patients from three unrelated Ashkenazi-Jewish ..
  29. Joshi V, Muzumdar D, Mahore A, Goel A. Posterolateral extrusion of C7-D1 intervertebral disc associated with intradiscal hematoma. Turk Neurosurg. 2011;21:446-8 pubmed publisher
    ..The clinical presentation, radiological features and surgical management of this rare condition are discussed and the relevant literature is briefly reviewed. ..
  30. Zipfel B, Zaefferer P, Riambau V, Szeberin Z, Weigang E, Menéndez M, et al. Worldwide results from the RESTORE II on elective endografting of thoracic aneurysms and dissections. J Vasc Surg. 2016;63:1466-75 pubmed publisher
    ..0% vs 7.2%). Perioperative neurologic complications were infrequent: paraplegia/paraparesis (2.9%) and stroke (0.6%) (vs 2.0% and 1.6% in the RESTORE registry)...
  31. Sharma S, Bagga R, Modi M. Paraparesis with complete recovery in antepartum eclampsia. Int J Gynaecol Obstet. 2006;93:242-3 pubmed
  32. Koyama S, Tomimatsu T, Kanagawa T, Sawada K, Tsutsui T, Kimura T, et al. Spinal subarachnoid hematoma following spinal anesthesia in a patient with HELLP syndrome. Int J Obstet Anesth. 2010;19:87-91 pubmed publisher
    ..on the posterior aspect of her right leg, noticed she was insensitive to bladder fullness and had mild flaccid paraparesis. Magnetic resonance imaging revealed a spinal subarachnoid hematoma with cauda equina compression...
  33. Kirresh A, Everitt A, Kon O, Dasgupta R, Pickering M, Lachmann H. Trapped without a diagnosis: Tumour necrosis factor receptor-associated periodic syndrome (TRAPS). Pract Neurol. 2016;16:304-7 pubmed publisher
    ..We describe a 49-year-old man with a self-limiting episode of paraparesis who reported recurrent bouts of abdominal symptoms and headaches since childhood...
  34. Akiyama Y, Koyanagi I, Mikuni N. Chronic Spinal Subdural Hematoma Associated with Antiplatelet Therapy. World Neurosurg. 2017;105:1032.e1-1032.e5 pubmed publisher
    ..A 71-year-old man was admitted to our hospital with 2 weeks' history of bilateral lower leg pain, dysesthesia, paraparesis, and urinary disturbance...
  35. Riesenman P, Farber M, Mauro M, Selzman C, Feins R. Aortoesophageal fistula after thoracic endovascular aortic repair and transthoracic embolization. J Vasc Surg. 2007;46:789-91 pubmed
    ..computed tomographic-guided transthoracic embolization, although the patient experienced lower extremity paraparesis postprocedurally...
  36. Bossens K, Bhatti S, Van Soens I, Gielen I, Van Ham L. Diffuse idiopathic skeletal hyperostosis of the spine in a nine-year-old cat. J Small Anim Pract. 2016;57:33-5 pubmed publisher
    A nine-year-old intact female domestic shorthair cat was evaluated for paraparesis, ataxia and severe spinal hyperaesthesia. Neurological examination indicated a T3-L3 spinal cord segment lesion...
  37. Carpentier A, Barez P, Hamaidia M, Gazon H, de Brogniez A, Perike S, et al. Modes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and Persistence. Viruses. 2015;7:3603-24 pubmed publisher
    ..cell Leukemia, ATL) and a spectrum of inflammatory diseases (mainly HTLV-associated myelopathy-tropical spastic paraparesis, HAM/TSP)...
  38. Batirel A, Erdem H, Sengoz G, Pehlivanoglu F, Ramosaco E, Gülsün S, et al. The course of spinal tuberculosis (Pott disease): results of the multinational, multicentre Backbone-2 study. Clin Microbiol Infect. 2015;21:1008.e9-1008.e18 pubmed publisher
    ..distribution of the posttreatment sequelae were as follows: 11% kyphosis, 6% Gibbus deformity, 5% scoliosis, 5% paraparesis, 5% paraplegia and 4% loss of sensation...
  39. Ahmed M, Al Khayat A, Al Murshedi F, Al Futaisi A, Chioza B, Pedro Fernandez Murray J, et al. A mutation of EPT1 (SELENOI) underlies a new disorder of Kennedy pathway phospholipid biosynthesis. Brain. 2017;140:547-554 pubmed publisher
    ..paraplegia, a highly heterogeneous group of neurodegenerative motor neuron disorders characterized by spastic paraparesis. Here, we report an unusual autosomal recessive neurodegenerative condition, best classified as a complicated ..
  40. Ozcakar L, Karadag O, Isik M, Elkiran E, Dikbas O, Altundag K. Progressive ascending paraparesia in an acute lymphoblastic leukemia patient: masked but not fallacious. J Exp Clin Cancer Res. 2004;23:365-6 pubmed
  41. Shea Y, Chu L, Chan A, Ha J, Li Y, Song Y. A systematic review of familial Alzheimer's disease: Differences in presentation of clinical features among three mutated genes and potential ethnic differences. J Formos Med Assoc. 2016;115:67-75 pubmed publisher
    ..3 ± 8.6 years, p < 0.001) and were more commonly affected by seizures, spastic paraparesis, myoclonus, and cerebellar signs (p < 0.001, p < 0.001, p = 0.003, and p = 0...
  42. Aiyer S, Shetty A, Kanna R, Maheswaran A, Rajasekaran S. Spinal cord herniation following cervical meningioma excision: a rare clinical entity and review of literature. Eur Spine J. 2016;25 Suppl 1:216-9 pubmed publisher
    ..These cases may present as paraparesis, Brown-sequard syndrome and rarely as in our case as monoparesis.
  43. Garcia N, Tehrani H, Morasch M, Pearce W, Matsumura J. Spinal cord ischemia following endovascular repair of an infrarenal aortic aneurysm. Ann Vasc Surg. 2002;16:509-12 pubmed
    ..Spinal cord ischemia following repair of an infrarenal aneurysm is a rare but recognized complication following endovascular repair of an infrarenal aneurysm. Here we discuss its possible mechanism. ..
  44. Jarius S, Wandinger K, Borowski K, Stoecker W, Wildemann B. Antibodies to CV2/CRMP5 in neuromyelitis optica-like disease: case report and review of the literature. Clin Neurol Neurosurg. 2012;114:331-5 pubmed publisher
    ..In addition, we provide a comprehensive review of all patients with CV2/CRMP5-Ab and NMO-like disease published in the English literature so far...
  45. Hobert M, Brauer C, Dziallas P, Gerhauser I, Algermissen D, Tipold A, et al. Infiltrative lipoma compressing the spinal cord in 2 large-breed dogs. Can Vet J. 2013;54:74-8 pubmed
    Two cases of infiltrative lipomas compressing the spinal cord and causing nonambulatory paraparesis in 2 large-breed dogs are reported...
  46. Trevino A, Aguilera A, Rodriguez Iglesias M, Hernandez A, Benito R, Roc L, et al. HTLV infection in HCV-antibody positive patients in Spain. AIDS Res Hum Retroviruses. 2017;: pubmed publisher
    ..HTLV underdiagnosis is highlighted by the high proportion of patients presenting either with tropical spastic paraparesis (TSP) or adult T-cell leukemia (ATL) at first diagnosis...
  47. Terrell S, Platt S, Chrisman C, Homer B, de Lahunta A, Summers B. Possible intraspinal metastasis of a canine spinal cord nephroblastoma. Vet Pathol. 2000;37:94-7 pubmed
    ..Hound was admitted to the University of Florida Veterinary Medical Teaching Hospital with progressive spastic paraparesis. At necropsy, intradural extramedullary tumors produced areas of spinal cord swelling and softening in spinal ..
  48. Handler J. Type B aortic dissection: management in a young man with neurologic sequelae. J Clin Hypertens (Greenwich). 2006;8:291-5 pubmed
  49. Singhal M, Kang M, Khadwal A, Duggal R, Rajwanshi A, Khandelwal N. An unusual presentation of congenital adrenocortical carcinoma: a case report and review of the literature. Cancer Imaging. 2012;12:118-21 pubmed publisher
    ..a case of congenital non-functional adrenocortical carcinoma in a male infant who presented with recurrent pneumonia, paraparesis and sclerotic skeletal metastasis. To the best of our knowledge such presentation has never been reported.
  50. Spallone A, Çelniku M. Massive Lumbar Disk Herniation Following "Therapeutic" Water Boiling of the Lower Extremities: Case Report and Literature Review. World Neurosurg. 2017;97:758.e7-758.e9 pubmed publisher
    ..A 49-year-old man came to our attention with severe flaccid paraparesis occurred 10 days before, almost immediately after he had immersed his legs in boiling water to treat his severe ..
  51. Coselli J, Amarasekara H, Green S, Price M, Preventza O, de la Cruz K, et al. Open Repair of Thoracoabdominal Aortic Aneurysm in Patients 50 Years Old and Younger. Ann Thorac Surg. 2017;103:1849-1857 pubmed publisher
    ..included adverse event, a composite endpoint that comprised operative death or persistent stroke, paraplegia, paraparesis, or renal failure requiring dialysis...
  52. Sridhar K, Vasudevan M. Idiopathic chronic hypertrophic pachymeningitis causing thoracic cord compression. Br J Neurosurg. 2004;18:515-7 pubmed
    ..The authors report the diagnostic dilemmas in a 48-year-old lady who presented with progressive spastic paraparesis of 4 months duration...
  53. Roca B. Intradural extramedullary tuberculoma of the spinal cord: a review of reported cases. J Infect. 2005;50:425-31 pubmed
    ..The disease presents insidiously with paraparesis, hypoesthesia with a sensory level, and bladder dysfunction, due to cord involvement or compression by the ..
  54. Kendall E, Gonzalez E, Espinoza I, Tipismana M, Verdonck K, Clark D, et al. Early neurologic abnormalities associated with human T-cell lymphotropic virus type 1 infection in a cohort of Peruvian children. J Pediatr. 2009;155:700-6 pubmed publisher
    Because human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) may occur in some children infected with HTLV-1, we sought to determine the prevalence of neurologic abnormalities and ..
  55. Figueiredo N. Motor exam of patients with spinal cord injury: a terminological imbroglio. Neurol Sci. 2017;38:1159-1165 pubmed publisher
    ..for the limbs, patients with complete injury affecting spinal cord segments C1-5 usually presents with "tetraplegia"; C6-T1 presents with "paraplegia and brachial diparesis"; T2-L2 with "paraplegia"; and L3-S1 with "paraparesis".
  56. Kim A, Maher C, Smith E. Lumbar intramedullary spinal schistosomiasis presenting as progressive paraparesis: case report. Neurosurgery. 2006;58:E996; discussion E996 pubmed
    ..We describe a patient with lumbar intramedullary spinal schistosomiasis who presented to a tertiary medical center in the United States and discuss the diagnosis and treatment of this rare disease...
  57. Moon S, Kang K, Park S, Lee A, Kim H, Kim W. A case of delayed diagnosis of paraparesis caused by a bone metastasis of renal cell carcinoma. Clin Nephrol. 2008;70:181-3 pubmed
  58. Sasani M, Ozer A, Oktenoglu T, Kaner T, Aydin S, Canbulat N, et al. Thoracoscopic surgical approaches for treating various thoracic spinal region diseases. Turk Neurosurg. 2010;20:373-81 pubmed publisher
    ..Thoracoscopic spine surgery is applicable to all patients with various spinal diseases. ..
  59. Harrington P, Millner P, Veale D. Inappropriate medical management of spinal epidural abscess. Ann Rheum Dis. 2001;60:218-22 pubmed with longstanding rheumatoid disease was referred to the regional spinal surgery unit with acute onset of paraparesis due to an extensive spinal epidural abscess of the lumbar spine...
  60. Keith J, Nicolle M, Tugaleva E, Shkrum M, Bilbao J, Hammond R. A patient with leg weakness. Can J Neurol Sci. 2007;34:92-8 pubmed
    ..West Nile Virus, along with other emerging infections, serves notice of the health care implications of humanity's globalization of ecosystems. ..
  61. Hellmann M, Djaldetti R, Luckman J, Dabby R. Thoracic sensory level as a false localizing sign in cervical spinal cord and brain lesions. Clin Neurol Neurosurg. 2013;115:54-6 pubmed publisher
    ..tertiary medical centers were reviewed for all patients who presented in 2000-2010 with a main complaint of paraparesis and a thoracic sensory level...
  62. Rosado J, Morales S, Lopez G, Clark D, Verdonck K, Gotuzzo E, et al. The FAS-670 AA genotype is associated with high proviral load in peruvian HAM/TSP patients. J Med Virol. 2017;89:726-731 pubmed publisher
    ..Human T-lymphotropic virus 1 (HTLV-1) is the etiologic agent of the HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)...
  63. Rinaldi M, Ranavolo A, Conforto S, Martino G, Draicchio F, Conte C, et al. Increased lower limb muscle coactivation reduces gait performance and increases metabolic cost in patients with hereditary spastic paraparesis. Clin Biomech (Bristol, Avon). 2017;48:63-72 pubmed publisher
    ..relationship with muscles spasticity, gait performance, and metabolic cost in patients with hereditary spastic paraparesis. Kinematic, kinetic, electromyographic and energetic parameters of 23 patients and 23 controls were evaluated ..
  64. Azodi S, Nair G, Enose Akahata Y, Charlip E, Vellucci A, Cortese I, et al. Imaging spinal cord atrophy in progressive myelopathies: HTLV-I-associated neurological disease (HAM/TSP) and multiple sclerosis (MS). Ann Neurol. 2017;82:719-728 pubmed publisher
    ..myelopathies, including human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and multiple sclerosis (MS)...
  65. Grove C, Robbins P, Kermode A. Intravascular lymphoma presenting as progressive paraparesis. J Clin Neurosci. 2008;15:1056-8 pubmed publisher
    We present a patient with subacute progressive paraparesis secondary to intravascular lymphoma restricted to the spinal cord where initial laboratory and imaging studies were inconclusive...
  66. Donas K, Lachat M, Rancic Z, Oberkofler C, Pfammatter T, Guber I, et al. Early and midterm outcome of a novel technique to simplify the hybrid procedures in the treatment of thoracoabdominal and pararenal aortic aneurysms. J Vasc Surg. 2009;50:1280-4 pubmed publisher
    ..Permanent neurologic deficit occurred in two cases (3.4%; paraplegia, n = 1; paraparesis, n = 1). The overall endoleak rate was 17...
  67. Ylikallio E, Rahikkala E, Keski Filppula R, Auranen M, Tyynismaa H. Adrenomyeloneuropathy due to mutation in the ABCD1 gene as underlying factor in spastic paraparesis. Duodecim. 2017;133:683-7 pubmed
    ..adrenomyeloneuropathy (AMN) caused by the mutation in the ABCD1 gene was revealed as the cause of spastic paraparesis. . Two patients had hypoadrenalism, which is in some cases some associated with the disease ...
  68. Nogueira R, Ferreira R, Grant P, Maier S, Koroshetz W, Gonzalez R, et al. Restricted diffusion in spinal cord infarction demonstrated by magnetic resonance line scan diffusion imaging. Stroke. 2012;43:532-5 pubmed publisher
    ..4 and 575.8 × 10(-6) mm(2)/s, with ADC ratios ranging between 39.4% and 57.4%. Line scan diffusion imaging is technically feasible and appears to be a reliable method to diagnose spinal cord infarction in the acute setting. ..
  69. Sahu R, Tungaria A, Pal L, Kumar R. Endometriosis of conus medullaris: a case report. Br J Neurosurg. 2013;27:842-4 pubmed publisher
    ..A twenty-five-year-old woman presented with acute onset paraparesis with bladder involvement of five-day duration...
  70. LaFrance W. Video NeuroImage: diagnosing conversion weakness with the Spinal Injuries Center test: when Hoover doesn't help. Neurology. 2008;71:e57 pubmed publisher
  71. Sasayama T, Mizukawa K, Sakagami Y, Mizowaki T, Tanaka K, Ohbayashi C, et al. Glioblastoma multiforme associated with klinefelter syndrome. Neurol Med Chir (Tokyo). 2009;49:532-5 pubmed
    ..The abnormal genetic constitution of this patient may have been directly responsible for the poor outcome. ..
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    ..We reported three asymptomatic and four symptomatic HTLV infections, including two tropical spastic paraparesis/HTLV-1 associated myelopathies (TSP/HAM) and two adult T-cell leukemia/lymphoma (ATLL), diagnosed between 2000 ..
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    ..His neurologic deficits were completely alleviated, and bony union was obtained. In our case, paraparesis followed relatively mild trauma because the spinal cord was predisposed to injury by continuous mechanical ..
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  76. Curis C, Percher F, Jeannin P, Montange T, Chevalier S, Seilhean D, et al. Human T-Lymphotropic Virus Type 1-Induced Overexpression of Activated Leukocyte Cell Adhesion Molecule (ALCAM) Facilitates Trafficking of Infected Lymphocytes through the Blood-Brain Barrier. J Virol. 2016;90:7303-7312 pubmed publisher
    ..agent of a slowly progressive neurodegenerative disease, HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP)...
  77. Schepens M, Heijmen R, Ranschaert W, Sonker U, Morshuis W. Thoracoabdominal aortic aneurysm repair: results of conventional open surgery. Eur J Vasc Endovasc Surg. 2009;37:640-5 pubmed publisher
    ..9%, 37 patients (6.5%) required postoperative dialysis and 47 patients (8.3%) developed paraplegia or paraparesis. The incidence of paraplegia in the left heart bypass group was 4.4%...
  78. Donas K, Torsello G, Lazaridis K. Current status of hybrid procedures for thoracoabdominal and pararenal aortic aneurysm repair: techniques and considerations. J Endovasc Ther. 2010;17:602-8 pubmed publisher
    ..We discuss critical issues that may influence outcomes with these advanced procedures. ..
  79. Rabellino M, Garcia Monaco R, Cesareo V, Rostagno R, Sola C. Endovascular treatment of iatrogenic aortic injury after spinal surgery. Minim Invasive Ther Allied Technol. 2013;22:56-60 pubmed publisher
    A 59-year-old female presented to our institution with paraparesis caused by medullar compression secondary to multiple myeloma. Spinal cord decompression and transpedicular spine fixation were performed...
  80. Seppälä M, Antinheimo J, Pohjola J, Hernesniemi J. [Acute spinal cord compression]. Duodecim. 2013;129:2655-60 pubmed
    ..A correct and non-delayed diagnosis and urgent release of the spinal cord from the compressed state are the cornerstones of successful treatment. ..
  81. Gygi M, Kathmann I, Konar M, Rottenberg S, Meylan M. [Paraparesis in a dwarf goat: clarification by means of magnetic resonance imaging]. Schweiz Arch Tierheilkd. 2004;146:523-8 pubmed
    A 4-year old pygmy goat with chronic paraparesis of the hindlimbs was referred to the Ruminant Clinic of the University of Berne. The causative lesion was localized to the thoracolumbar spinal cord after a thorough clinical examination...
  82. Scherer K, Skeen M, Strine S, Juel V. Hanging leg syndrome: combined bilateral femoral and sciatic neuropathies. Neurology. 2006;66:1124-5 pubmed
  83. Yesilot N, Mutlu M, Gungor O, Baykal B, Serdaroglu P, Akman Demir G. Clinical characteristics and course of spinal cord involvement in Behçet's disease. Eur J Neurol. 2007;14:729-37 pubmed
    ..05). Our study suggests that spinal cord involvement has even worse prognosis compared with other types of p-NBD. Therefore, recognition of spinal cord involvement in Behçet's patients should prompt early vigorous treatment. ..
  84. Silva J, Taricco M, Brito J, Neves V, Farias R. [Constrictive arachnoiditis after pantopaque myelography causing syringomyelia and paraparesis: case report]. Arq Neuropsiquiatr. 2001;59:619-22 pubmed
    ..We present an unusual case of thoracic constrictive arachnoiditis after pantopaque myelography, used 10 years before in the diagnosis of intradural arachnoid cyst. ..
  85. Saito S, Hoshi S, Sakai K, Chiba Y, Saito H, Hatori M, et al. Post-laminectomy long-term survival of a patient with spinal cord compression secondary to metastatic prostate cancer. Int J Clin Oncol. 2004;9:520-2 pubmed
    ..Here we report on a prostate cancer patient with spinal cord compression who became ambulant from paraparesis after he underwent a decompression laminectomy; he survived for 9.5 years with good quality of life.
  86. Szekely G, Miltenyi Z, Mezey G, Simon Z, Gyarmati J, Gergely L, et al. Epidural malignant lymphomas of the spine: collected experiences with epidural malignant lymphomas of the spinal canal and their treatment. Spinal Cord. 2008;46:278-81 pubmed
    ..The epidural presentation in eight patients was heralded by motor signs (paraparesis and plegia), in one by a lesion of the posterior columns of the spinal cord (ataxia), and in three by pain...
  87. Crnković M, Matijević Mikelić V, Demarin V, Kosicek T, Morovic S, Grazio S. Risk factors for gross motor dysfunction of lower limbs in children. Acta Clin Croat. 2011;50:361-6 pubmed
    ..this study was to identify risk factors for neurological development in children aged 1 to 3 years with a mild paraparesis form of motor development of lower extremities...
  88. Obeid I, Vital J, Aurouer N, Hansen S, Gangnet N, Pointillart V, et al. Intraspinal canal rod migration causing late-onset paraparesis 8 years after scoliosis surgery. Eur Spine J. 2016;25:2097-101 pubmed publisher
    ..The very low virulence of the strain of Propionibacterium acnes is probably involved in this particular presentation where the rod was trapped in the canal, owing to the quite extensive laminar reconstitution. ..
  89. Umeki K, Umekita K, Hashikura Y, Yamamoto I, Kubo K, Nagatomo Y, et al. Evaluation of Line Immunoassay to Detect HTLV-1 Infection in an Endemic Area, Southwestern Japan; Comparison with Polymerase Chain Reaction and Western Blot. Clin Lab. 2017;63:227-233 pubmed publisher
    ..has been recognized as a cause of adult T-cell leukemia/lymphoma, HTLV-1-associated myelopathy/tropical spastic paraparesis, and HTLV-1-associated uveitis...
  90. Agrawal A, Shetty B, Makannavar J, Shetty L, Shetty J, Shetty V. Intramedullary endometriosis of the conus medullaris: case report. Neurosurgery. 2006;59:E428; discussion E428 pubmed
    ..Intraspinal endometriosis must be recognized as a potential cause of periodic neurological signs and symptoms in young and middle-aged women. ..
  91. Xiong G, Guan Y, Hong Y, Zhang J, Guan H. Motor unit number estimation may be a useful method to evaluate motor function recovery after spinal cord transection in rats. Spinal Cord. 2010;48:363-6 pubmed publisher
    ..Time-dependent changes in the functional motor unit number may occur in spinal segments caudal to the transection level, and MUNE could be a useful method to evaluate motor function recovery. ..
  92. Andersen N, Williams J, Hanna J, Shah A, McCann R, Hughes G. Results with an algorithmic approach to hybrid repair of the aortic arch. J Vasc Surg. 2013;57:655-67; discussion 666-7 pubmed publisher
    ..The 30-day/in-hospital rates of stroke and permanent paraplegia or paraparesis were 4.6% (n = 4) and 1.2% (n = 1)...