frontal lobe

Summary

Summary: The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.

Top Publications

  1. Takakusaki K. Neurophysiology of gait: from the spinal cord to the frontal lobe. Mov Disord. 2013;28:1483-91 pubmed publisher
    ..These processes enable the corticospinal system to generate limb trajectory and achieve accurate foot placement. Loops from the motor cortical areas to the basal ganglia and the cerebellum can serve this purpose. ..
  2. Soltirovska Salamon A, Groenendaal F, van Haastert I, Rademaker K, Benders M, Koopman C, et al. Neuroimaging and neurodevelopmental outcome of preterm infants with a periventricular haemorrhagic infarction located in the temporal or frontal lobe. Dev Med Child Neurol. 2014;56:547-55 pubmed publisher
    ..PVHI located in the temporal or frontal lobe is almost invariably related to a typical motor outcome, but carries a risk of cognitive, behavioural, and ..
  3. van Blitterswijk M, DeJesus Hernandez M, Niemantsverdriet E, Murray M, Heckman M, Diehl N, et al. Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study. Lancet Neurol. 2013;12:978-88 pubmed publisher
  4. Szczepanski S, Pinsk M, Douglas M, Kastner S, Saalmann Y. Functional and structural architecture of the human dorsal frontoparietal attention network. Proc Natl Acad Sci U S A. 2013;110:15806-11 pubmed publisher
  5. Gendron T, Bieniek K, Zhang Y, Jansen West K, Ash P, Caulfield T, et al. Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS. Acta Neuropathol. 2013;126:829-44 pubmed publisher
    ..These findings provide mechanistic insight into the pathogenesis of c9FTD/ALS, and have significant implications for therapeutic strategies. ..
  6. Savignac H, Corona G, Mills H, Chen L, Spencer J, Tzortzis G, et al. Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-D-aspartate receptor subunits and D-serine. Neurochem Int. 2013;63:756-64 pubmed publisher
    ..Our data therefore, provide a sound basis to further investigate the utility of prebiotics in the maintenance of brain health and adjunctive treatment of neuropsychiatric disorders. ..
  7. Mizielinska S, Lashley T, Norona F, Clayton E, Ridler C, Fratta P, et al. C9orf72 frontotemporal lobar degeneration is characterised by frequent neuronal sense and antisense RNA foci. Acta Neuropathol. 2013;126:845-57 pubmed publisher
    ..These data establish that sense and antisense C9orf72 repeat RNA foci are a consistent and specific feature of C9FTLD, providing new insight into the pathogenesis of C9FTLD. ..
  8. Cohen O, Vakil E, Tanne D, Molshatzki N, Nitsan Z, Hassin Baer S. The frontal assessment battery as a tool for evaluation of frontal lobe dysfunction in patients with Parkinson disease. J Geriatr Psychiatry Neurol. 2012;25:71-7 pubmed publisher
    ..The Frontal Assessment Battery (FAB) was developed to assess frontal lobe functions...
  9. Lindberg O, Manzouri A, Westman E, Wahlund L. A comparison between volumetric data generated by voxel-based morphometry and manual parcellation of multimodal regions of the frontal lobe. AJNR Am J Neuroradiol. 2012;33:1957-63 pubmed publisher
    ..The purpose of this study was to compare volumetric data generated by MM and VBM on 4 multimodal regions in the frontal lobe. We investigated 4 multimodal frontocortical regions by MM and VBM in patients with frontotemporal lobar ..
  10. De Lafuente V, Romo R. Dopaminergic activity coincides with stimulus detection by the frontal lobe. Neuroscience. 2012;218:181-4 pubmed publisher
    ..In agreement with previous findings, these data suggest that sensory evoked DA activity does not signal a stimulus physical presence but arises from the output of a perceptual decision. ..

Detail Information

Publications134 found, 100 shown here

  1. Takakusaki K. Neurophysiology of gait: from the spinal cord to the frontal lobe. Mov Disord. 2013;28:1483-91 pubmed publisher
    ..These processes enable the corticospinal system to generate limb trajectory and achieve accurate foot placement. Loops from the motor cortical areas to the basal ganglia and the cerebellum can serve this purpose. ..
  2. Soltirovska Salamon A, Groenendaal F, van Haastert I, Rademaker K, Benders M, Koopman C, et al. Neuroimaging and neurodevelopmental outcome of preterm infants with a periventricular haemorrhagic infarction located in the temporal or frontal lobe. Dev Med Child Neurol. 2014;56:547-55 pubmed publisher
    ..PVHI located in the temporal or frontal lobe is almost invariably related to a typical motor outcome, but carries a risk of cognitive, behavioural, and ..
  3. van Blitterswijk M, DeJesus Hernandez M, Niemantsverdriet E, Murray M, Heckman M, Diehl N, et al. Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study. Lancet Neurol. 2013;12:978-88 pubmed publisher
  4. Szczepanski S, Pinsk M, Douglas M, Kastner S, Saalmann Y. Functional and structural architecture of the human dorsal frontoparietal attention network. Proc Natl Acad Sci U S A. 2013;110:15806-11 pubmed publisher
  5. Gendron T, Bieniek K, Zhang Y, Jansen West K, Ash P, Caulfield T, et al. Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS. Acta Neuropathol. 2013;126:829-44 pubmed publisher
    ..These findings provide mechanistic insight into the pathogenesis of c9FTD/ALS, and have significant implications for therapeutic strategies. ..
  6. Savignac H, Corona G, Mills H, Chen L, Spencer J, Tzortzis G, et al. Prebiotic feeding elevates central brain derived neurotrophic factor, N-methyl-D-aspartate receptor subunits and D-serine. Neurochem Int. 2013;63:756-64 pubmed publisher
    ..Our data therefore, provide a sound basis to further investigate the utility of prebiotics in the maintenance of brain health and adjunctive treatment of neuropsychiatric disorders. ..
  7. Mizielinska S, Lashley T, Norona F, Clayton E, Ridler C, Fratta P, et al. C9orf72 frontotemporal lobar degeneration is characterised by frequent neuronal sense and antisense RNA foci. Acta Neuropathol. 2013;126:845-57 pubmed publisher
    ..These data establish that sense and antisense C9orf72 repeat RNA foci are a consistent and specific feature of C9FTLD, providing new insight into the pathogenesis of C9FTLD. ..
  8. Cohen O, Vakil E, Tanne D, Molshatzki N, Nitsan Z, Hassin Baer S. The frontal assessment battery as a tool for evaluation of frontal lobe dysfunction in patients with Parkinson disease. J Geriatr Psychiatry Neurol. 2012;25:71-7 pubmed publisher
    ..The Frontal Assessment Battery (FAB) was developed to assess frontal lobe functions...
  9. Lindberg O, Manzouri A, Westman E, Wahlund L. A comparison between volumetric data generated by voxel-based morphometry and manual parcellation of multimodal regions of the frontal lobe. AJNR Am J Neuroradiol. 2012;33:1957-63 pubmed publisher
    ..The purpose of this study was to compare volumetric data generated by MM and VBM on 4 multimodal regions in the frontal lobe. We investigated 4 multimodal frontocortical regions by MM and VBM in patients with frontotemporal lobar ..
  10. De Lafuente V, Romo R. Dopaminergic activity coincides with stimulus detection by the frontal lobe. Neuroscience. 2012;218:181-4 pubmed publisher
    ..In agreement with previous findings, these data suggest that sensory evoked DA activity does not signal a stimulus physical presence but arises from the output of a perceptual decision. ..
  11. Wandschneider B, Thompson P, Vollmar C, Koepp M. Frontal lobe function and structure in juvenile myoclonic epilepsy: a comprehensive review of neuropsychological and imaging data. Epilepsia. 2012;53:2091-8 pubmed publisher
    ..quot; ..
  12. Braakman H, Vaessen M, Jansen J, Debeij van Hall M, de Louw A, Hofman P, et al. Frontal lobe connectivity and cognitive impairment in pediatric frontal lobe epilepsy. Epilepsia. 2013;54:446-54 pubmed publisher
    Cognitive impairment is frequent in children with frontal lobe epilepsy (FLE), but its etiology is unknown...
  13. Quinn C, Elman L, McCluskey L, Hoskins K, Karam C, Woo J, et al. Frontal lobe abnormalities on MRS correlate with poor letter fluency in ALS. Neurology. 2012;79:583-8 pubmed publisher
    To examine whether frontal lobe abnormalities on magnetic resonance spectroscopy (MRS) in amyotrophic lateral sclerosis (ALS) correlate with poor letter fluency (LF)...
  14. Granziera C, Romascano D, Daducci A, Roche A, Vincent M, Krueger G, et al. Migraineurs without aura show microstructural abnormalities in the cerebellum and frontal lobe. Cerebellum. 2013;12:812-8 pubmed publisher
    ..HC and vs. MWA. The pathophysiological implications of these findings are discussed in light of recent literature. ..
  15. Coppe S, Orban de Xivry J, Yuksel D, Ivanoiu A, Lefevre P. Dramatic impairment of prediction due to frontal lobe degeneration. J Neurophysiol. 2012;108:2957-66 pubmed publisher
    ..Therefore, FTLD patients were only impaired when the predicted timing of an external event was required to elicit an action. These results argue in favor of a role of the frontal lobes in predictive movement timing. ..
  16. Woolgar A, Bor D, Duncan J. Global increase in task-related fronto-parietal activity after focal frontal lobe lesion. J Cogn Neurosci. 2013;25:1542-52 pubmed publisher
    ..Using fMRI, we ask how focal frontal lobe damage affects MD activity during a standard fluid intelligence task...
  17. Roesch M, Bryden D, Cerri D, Haney Z, Schoenbaum G. Willingness to wait and altered encoding of time-discounted reward in the orbitofrontal cortex with normal aging. J Neurosci. 2012;32:5525-33 pubmed publisher
    ..These results suggest that natural aging results in altered representations of reward in orbitofrontal cortex. These changes may relate to the increased ability to delay gratification and reduced impulsivity associated with aging. ..
  18. Marcotte K, Adrover Roig D, Damien B, de Préaumont M, Généreux S, Hubert M, et al. Therapy-induced neuroplasticity in chronic aphasia. Neuropsychologia. 2012;50:1776-86 pubmed publisher
    ..Also our results suggest that greater SFA improvement in chronic aphasia is associated with recruitment of areas in the left hemisphere...
  19. Wymbs N, Bassett D, Mucha P, Porter M, Grafton S. Differential recruitment of the sensorimotor putamen and frontoparietal cortex during motor chunking in humans. Neuron. 2012;74:936-46 pubmed publisher
    ..Across subjects, there was an aggregate increase in chunk strength (concatenation) with training, suggesting that subcortical circuits play a direct role in the creation of fluid transitions across chunks. ..
  20. Mylius V, Zouari H, Ayache S, Farhat W, Lefaucheur J. Stroke rehabilitation using noninvasive cortical stimulation: aphasia. Expert Rev Neurother. 2012;12:973-82 pubmed
    ..However, recent studies also showed some positive effects of the reinforcement of neural activities in the contralateral right hemisphere, based on the potential compensatory role of the nondominant hemisphere in stroke recovery...
  21. Weissman D, Carp J. The congruency effect in the posterior medial frontal cortex is more consistent with time on task than with response conflict. PLoS ONE. 2013;8:e62405 pubmed publisher
    ..These findings appear more consistent with the time on task account of the congruency effect than with the conflict monitoring account. ..
  22. Stern E, Fitzgerald K, Welsh R, Abelson J, Taylor S. Resting-state functional connectivity between fronto-parietal and default mode networks in obsessive-compulsive disorder. PLoS ONE. 2012;7:e36356 pubmed publisher
  23. Ernst A, Ma D, Garcia Perez I, Tsang T, Kluge W, Schwarz E, et al. Molecular validation of the acute phencyclidine rat model for schizophrenia: identification of translational changes in energy metabolism and neurotransmission. J Proteome Res. 2012;11:3704-14 pubmed publisher
  24. Emerson R, Cantlon J. Early math achievement and functional connectivity in the fronto-parietal network. Dev Cogn Neurosci. 2012;2 Suppl 1:S139-51 pubmed publisher
    ..We suggest that the functional intersection of number-related frontal and parietal regions is math-specific. ..
  25. Jackowski A, Araújo Filho G, Almeida A, Araújo C, Reis M, Nery F, et al. The involvement of the orbitofrontal cortex in psychiatric disorders: an update of neuroimaging findings. Rev Bras Psiquiatr. 2012;34:207-12 pubmed
    ..However, future studies are clearly needed to characterize the specific role of OFC on each PD as well as understanding its role in both normal and pathological behavior, mood regulation and cognitive functioning. ..
  26. Sundermann B, Pfleiderer B. Functional connectivity profile of the human inferior frontal junction: involvement in a cognitive control network. BMC Neurosci. 2012;13:119 pubmed publisher
    ..The IFJ is therefore introduced as a convenient starting point to investigate the cognitive control network in further studies. ..
  27. Fedorenko E, Duncan J, Kanwisher N. Language-selective and domain-general regions lie side by side within Broca's area. Curr Biol. 2012;22:2059-62 pubmed publisher
    In 1861, Paul Broca stood up before the Anthropological Society of Paris and announced that the left frontal lobe was the seat of speech...
  28. Liu F, Guo W, Liu L, Long Z, Ma C, Xue Z, et al. Abnormal amplitude low-frequency oscillations in medication-naive, first-episode patients with major depressive disorder: a resting-state fMRI study. J Affect Disord. 2013;146:401-6 pubmed publisher
    ..These findings indicated LFOs abnormalities in MDD and the fALFF analysis might be a potential approach in further exploration of this disorder. ..
  29. Amunts K, Zilles K. Architecture and organizational principles of Broca's region. Trends Cogn Sci. 2012;16:418-26 pubmed publisher
    ..This novel segregational concept of structural and functional architecture more adequately reflects the various functions of Broca's region in cognitive and/or linguistic processes. ..
  30. Tsuchida A, Fellows L. Are core component processes of executive function dissociable within the frontal lobes? Evidence from humans with focal prefrontal damage. Cortex. 2013;49:1790-800 pubmed publisher
    ..These findings are easier to reconcile with modular, material-specific accounts than with more unitary models of executive function. ..
  31. Samson R, Barnes C. Impact of aging brain circuits on cognition. Eur J Neurosci. 2013;37:1903-15 pubmed publisher
    ..Certain cognitive constructs that reflect the function of these areas lend themselves to investigation across species, allowing brain mechanisms at different levels of analysis to be studied in greater depth. ..
  32. Cao B, Wei Q, Ou R, Yang J, Shang H. Association of serum uric acid level with cognitive function among patients with multiple system atrophy. J Neurol Sci. 2015;359:363-6 pubmed publisher
    ..Our objective is to clarify the correlations between serum uric acid and cognitive function as well as frontal lobe function in Chinese MSA patients...
  33. Maidan I, Nieuwhof F, Bernad Elazari H, Reelick M, Bloem B, Giladi N, et al. The Role of the Frontal Lobe in Complex Walking Among Patients With Parkinson's Disease and Healthy Older Adults: An fNIRS Study. Neurorehabil Neural Repair. 2016;30:963-971 pubmed
    ..To investigate the role of the frontal lobe during DT and obstacle negotiation, in healthy older adults and patients with Parkinson's disease (PD)...
  34. Damier P. Why do Parkinson's Disease Patients Sometimes Make Wrong Decisions?. J Parkinsons Dis. 2015;5:637-42 pubmed publisher
    ..Attention disorders and frontal lobe dysfunction, highly prevalent in the course of PD, are other factors that may alter a patient's decision making...
  35. Maestri M, Carnicelli L, Economou N, Bonakis A, Paparrigopoulos T, Papageorgiou S, et al. NREM sleep transient events in fronto-temporal dementia: beyond sleep stage architecture. Arch Ital Biol. 2015;153:214-24 pubmed publisher
    ..Sleep impairment in FTD may be specifically related to the specific frontal lobe involvement in the neurodegenerative process...
  36. Matsuda Y, Hamayasu H, Seki A, Nonaka K, Wang T, Matsumoto T, et al. Presence of Citrullinated Histone H3-Positive Neutrophils in Microscopic Polyangiitis from the Early Phase: An Autopsy Proven Case. Pathol Int. 2016;66:466-71 pubmed publisher
    ..The lungs showed intra-alveolar hemorrhage due to capillaritis. Severe brain hemorrhage was found in the left frontal lobe and putamen with uncal herniation. No vasculitis or thrombi was observed in the brain...
  37. Gold J, Sher Y, Maldonado J. Frontal Lobe Epilepsy: A Primer for Psychiatrists and a Systematic Review of Psychiatric Manifestations. Psychosomatics. 2016;57:445-64 pubmed publisher
    b>Frontal lobe epilepsy (FLE) can masquerade as a primary psychiatric condition, be misdiagnosed in-lieu of a true psychiatric disorder, or may be comorbid with psychiatric illness...
  38. Pereira Pedro A, Masters M, Bruner E. Shape analysis of spatial relationships between orbito-ocular and endocranial structures in modern humans and fossil hominids. J Anat. 2017;231:947-960 pubmed publisher
    ..Seventeen landmarks and semi-landmarks that capture the outline of the eye, frontal lobe, anterior fossa/orbital roof and the position of the temporal tips were sampled using lateral scout views in ..
  39. Freedman M, Binns M, Gao F, Holmes M, Roseborough A, Strother S, et al. Mind-Matter Interactions and the Frontal Lobes of the Brain: A Novel Neurobiological Model of Psi Inhibition. Explore (NY). 2018;14:76-85 pubmed publisher
    ..We used mind-matter interactions to study psi in two participants with frontal lobe damage...
  40. Gonzales L, Benefit B, Mccrossin M, Spoor F. Cerebral complexity preceded enlarged brain size and reduced olfactory bulbs in Old World monkeys. Nat Commun. 2015;6:7580 pubmed publisher
    ..However, the Victoriapithecus brain has principal and arcuate sulci of the frontal lobe not seen in the stem catarrhine Aegyptopithecus, as well as a distinctive cercopithecoid pattern of ..
  41. Ene C, Nerva J, McGrath L, Flanagan M, Chamberlain M, Silbergeld D. Flow-Related Aneurysm within Glioblastoma: A Case Report and Review of Literature. World Neurosurg. 2016;89:729.e1-6 pubmed publisher
    ..and magnetic resonance imaging revealed a hypervascular lesion, likely high-grade glioma, in the right frontal lobe, with a dilated vessel within the tumor...
  42. Smith J, Jack M, Peterson J, Chamoun R. Herniated gyrus rectus causing idiopathic compression of the optic chiasm. Clin Neurol Neurosurg. 2017;153:79-81 pubmed publisher
    Anomalies in the frontal lobe can interfere with visual function by compression of the optic chiasm and nerve. The gyrus rectus is located at the anterior cranial fossa floor superior to the intracranial optic nerves and chiasm...
  43. Pereira R, Bonardi J, Ferreira A, Latini G. An unusual case of dental infection by Pseudomonas aeruginosa causing a brain abscess: case report. Aust Dent J. 2017;62:523-527 pubmed publisher
    ..After computed tomography was performed, she was diagnosed with a brain abscess in the frontal lobe with the involvement of the maxillary right first molar, the maxillary sinus, the ethmoid sinus and the orbital ..
  44. Szyfter W, Bartochowska A, Borucki Å, Maciejewski A, Kruk Zagajewska A. Simultaneous treatment of intracranial complications of paranasal sinusitis. Eur Arch Otorhinolaryngol. 2018;275:1165-1173 pubmed publisher
    ..Seventy-three intracranial complications were found among 51 patients. Of the 51 patients, 25 had frontal lobe abscesses (including multiple abscesses)...
  45. Yu B, Wen L, Xiao B, Han F, Shi Y. Single Prolonged Stress induces ATF6 alpha-dependent Endoplasmic reticulum stress and the apoptotic process in medial Frontal Cortex neurons. BMC Neurosci. 2014;15:115 pubmed publisher
  46. Jolles D, Wassermann D, Chokhani R, Richardson J, Tenison C, Bammer R, et al. Plasticity of left perisylvian white-matter tracts is associated with individual differences in math learning. Brain Struct Funct. 2016;221:1337-51 pubmed publisher
    ..More generally, our quantitative approach will be useful for future studies examining longitudinal changes in white matter integrity associated with cognitive skill development. ..
  47. Sun P, Wei S, Wei X, Wang J, Zhang Y, Qiao M, et al. Anger Emotional Stress Influences VEGF/VEGFR2 and Its Induced PI3K/AKT/mTOR Signaling Pathway. Neural Plast. 2016;2016:4129015 pubmed publisher
    ..As VEGFR2 can promote neurogenesis and vasculogenesis in the hippocampus and frontal lobe, these results suggest that anger emotional stress can result in decreased neurogenesis.
  48. Lee S, Yun T, Kang K, Rhim J, Park C, Kim T, et al. Application of diffusion-weighted imaging and dynamic susceptibility contrast perfusion-weighted imaging for ganglioglioma in adults: Comparison study with oligodendroglioma. J Neuroradiol. 2016;43:331-8 pubmed publisher
    ..GGs occurred more frequently in the temporal lobe than in the frontal lobe. GGs showed a smaller tumor volume, and higher ratio of enhancing portion per tumor volume than ODGs (P=...
  49. Foster P, Drago V, Ferguson B, Harrison P, Harrison D. Quantitative electroencephalographic and neuropsychological investigation of an alternative measure of frontal lobe executive functions: the Figure Trail Making Test. Brain Inform. 2015;2:239-251 pubmed
    The most frequently used measures of executive functioning are either sensitive to left frontal lobe functioning or bilateral frontal functioning...
  50. Ascherl R, Sorge I, Thome U, Hirsch F, Bläser A, Kiess W, et al. Severe gyration and migration disorder in fetofetal transfusion syndrome: two case reports and a review of the literature on the neurological outcome of children with lesions on neuroimaging. Childs Nerv Syst. 2018;34:155-163 pubmed publisher
    ..Interestingly, cranial MRI revealed medial frontal lobe polymicrogyria, ventriculomegaly, and decreased thickness in both parietal lobes in both donors...
  51. Kwan Y, Baek C, Chung S, Kim T, Choi S. Resting-state quantitative EEG characteristics of insomniac patients with depression. Int J Psychophysiol. 2018;124:26-32 pubmed publisher
    ..However, depression that often coexists with insomnia exhibits hypo-activity in the frontal lobe, which is very different from insomnia...
  52. Quaedflieg C, Smulders F, Meyer T, Peeters F, Merckelbach H, Smeets T. The validity of individual frontal alpha asymmetry EEG neurofeedback. Soc Cogn Affect Neurosci. 2016;11:33-43 pubmed publisher
    ..Individual differences in trainability were also reflected in the ability to change frontal asymmetry during the feedback. ..
  53. Hu Y, Jiang Y, Hu P, Ma H, Wang K. Impaired social cognition in patients with interictal epileptiform discharges in the frontal lobe. Epilepsy Behav. 2016;57:46-54 pubmed publisher
    ..We divided the patients into those having frontal lobe interictal epileptiform discharges (group with frontal IEDs) and those with seizures originating outside the ..
  54. Xing D, Jenson E, Zwick C, Rodriguez F, Kurman R. Atypical Proliferative (Borderline) Serous Tumor in the Brain: A Case Report. Int J Gynecol Pathol. 2018;37:52-56 pubmed publisher
    ..of the breast was found on a follow-up computed tomography scan of her brain to have a 1-cm lesion in the right frontal lobe in 2008...
  55. Mimura N, Inoue T, Shimotake A, Matsumoto R, Ikeda A, Takahashi R. A case of epilepsy induced by eating or by visual stimuli of food made of minced meat. Rinsho Shinkeigaku. 2017;57:430-435 pubmed publisher
    ..In this patient, seizures were provoked not only by eating particular foods but also by seeing these. This suggests a form of epilepsy involving visual stimuli. ..
  56. Krueger C, Dean D, Rosen H, Halabi C, Weiner M, Miller B, et al. Longitudinal rates of lobar atrophy in frontotemporal dementia, semantic dementia, and Alzheimer's disease. Alzheimer Dis Assoc Disord. 2010;24:43-8 pubmed publisher
    ..In FTD the rate of frontal lobe atrophy over 1 year was greater than in any other group, whereas SD showed the highest rate in the temporal ..
  57. Margulies D, Petrides M. Distinct parietal and temporal connectivity profiles of ventrolateral frontal areas involved in language production. J Neurosci. 2013;33:16846-52 pubmed publisher
    ..These findings provide a major improvement in understanding the connectivity of the areas in the ventrolateral frontal region that are involved in language production. ..
  58. Phoumthipphavong V, Barthas F, Hassett S, Kwan A. Longitudinal Effects of Ketamine on Dendritic Architecture In Vivo in the Mouse Medial Frontal Cortex. Eneuro. 2016;3: pubmed publisher
    ..These dynamic structural modifications are consistent with a model of ketamine action in which the net effect is a rebalancing of synaptic inputs received by frontal cortical neurons. ..
  59. Pastori C, Francione S, Pelle F, de Curtis M, Gnatkovsky V. Fluency tasks generate beta-gamma activity in language-related cortical areas of patients during stereo-EEG monitoring. Brain Lang. 2016;163:50-56 pubmed publisher
    ..All patients were right-handed and were explored with depth electrodes in the dominant frontal lobe. We demonstrate that fluency tasks enhance beta-gamma frequencies and reduce background activities in language ..
  60. Sammut L, Wallis D, Holroyd C. Progressive multifocal leukoencephalopathy associated with infliximab. J R Coll Physicians Edinb. 2016;46:163-165 pubmed publisher
    ..white matter signal abnormality consistent with demyelination was seen in the antero-inferior left frontal lobe extending into the frontal opercular white matter and into the left temporal lobe white matter...
  61. Smirni D, Turriziani P, Mangano G, Bracco M, Oliveri M, Cipolotti L. Modulating phonemic fluency performance in healthy subjects with transcranial magnetic stimulation over the left or right lateral frontal cortex. Neuropsychologia. 2017;102:109-115 pubmed publisher
    ..For example, application of inhibitory rTMS or tDCs over the right frontal lobe of dysphasic patients resulted in improved naming abilities...
  62. Sebastian A, Jung P, Neuhoff J, Wibral M, Fox P, Lieb K, et al. Dissociable attentional and inhibitory networks of dorsal and ventral areas of the right inferior frontal cortex: a combined task-specific and coordinate-based meta-analytic fMRI study. Brain Struct Funct. 2016;221:1635-51 pubmed publisher
    ..The current study provides decisive evidence regarding a more precise functional characterization of rIFC subregions in attention and inhibition. ..
  63. Krudop W, Kerssens C, Dols A, Prins N, Möller C, Schouws S, et al. Identifying bvFTD Within the Wide Spectrum of Late Onset Frontal Lobe Syndrome: A Clinical Approach. Am J Geriatr Psychiatry. 2015;23:1056-66 pubmed publisher
    ..to diagnose because of the extensive differential diagnosis, including many other diseases presenting with a frontal lobe syndrome...
  64. Ekman M, Fiebach C, Melzer C, Tittgemeyer M, Derrfuss J. Different Roles of Direct and Indirect Frontoparietal Pathways for Individual Working Memory Capacity. J Neurosci. 2016;36:2894-903 pubmed publisher
  65. Rocca M, Vacchi L, Rodegher M, Meani A, Martinelli V, Possa F, et al. Mapping face encoding using functional MRI in multiple sclerosis across disease phenotypes. Brain Imaging Behav. 2017;11:1238-1247 pubmed publisher
    ..In SPMS patients, abnormal functional recruitment of frontal lobe areas might contribute to the severity of clinical manifestations.
  66. Ayton S, Fazlollahi A, Bourgeat P, Raniga P, Ng A, Lim Y, et al. Cerebral quantitative susceptibility mapping predicts amyloid-?-related cognitive decline. Brain. 2017;140:2112-2119 pubmed publisher
    ..104 (0.05), P = 0.036] and frontal lobe [?(standard error) = -0.154 (0.055), P = 0.006]...
  67. Nishimura T, Maruguchi H, Nakao A, Nakayama S. Unusual complications from amitriptyline intoxication. BMJ Case Rep. 2017;2017: pubmed publisher
    ..MRI presented irreversible damage to the bilateral frontal lobe and insula...
  68. de Andrade L, Gobbi L, Coelho F, Christofoletti G, Costa J, Stella F. Benefits of multimodal exercise intervention for postural control and frontal cognitive functions in individuals with Alzheimer's disease: a controlled trial. J Am Geriatr Soc. 2013;61:1919-26 pubmed publisher
    ..001, partial ?(2) = 0.676) after the 16-week period. Intervention participants performed better on dual-task activities and had better postural balance and greater functional capacity than controls. ..
  69. Hassall C, Silver A, Turk D, Krigolson O. We are more selfish than we think: The endowment effect and reward processing within the human medial-frontal cortex. Q J Exp Psychol (Hove). 2016;69:1676-86 pubmed publisher
    ..Importantly, our findings provide additional evidence for a self-ownership bias in cognitive processing and further demonstrate the insensitivity of the medial-frontal reward system to gambles for another. ..
  70. Alonso J, Romero S, Mananas M, Alcalá M, Antonijoan R, Giménez S. Acute Sleep Deprivation Induces a Local Brain Transfer Information Increase in the Frontal Cortex in a Widespread Decrease Context. Sensors (Basel). 2016;16: pubmed publisher
    ..TE is an objective measure that could be used as a potential measure of sleep pressure and somnolence with the additional property of directed relationships. ..
  71. Morosawa S, Iritani S, Fujishiro H, Sekiguchi H, Torii Y, Habuchi C, et al. Neuropeptide Y neuronal network dysfunction in the frontal lobe of a genetic mouse model of schizophrenia. Neuropeptides. 2017;62:27-35 pubmed publisher
    ..DISC1 dysfunction may be involved in the pathogenesis of schizophrenia through the impairment of the NPY neuronal network. ..
  72. Abrahamov D, Levran O, Naparstek S, Refaeli Y, Kaptson S, Abu Salah M, et al. Blood-Brain Barrier Disruption After Cardiopulmonary Bypass: Diagnosis and Correlation to Cognition. Ann Thorac Surg. 2017;104:161-169 pubmed publisher
    ..2 ± 12 vs 95.1 ± 11, p = 0.032), predominantly in executive and attention (frontal lobe-related) functions (91.8 ± 13 vs 86.9 ± 12, p = 0.042)...
  73. Irwin D, Lleo A, Xie S, McMillan C, Wolk D, Lee E, et al. Ante mortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration. Ann Neurol. 2017;82:247-258 pubmed publisher
    ..Autopsy-confirmed samples are critical for FTLD biomarker development and validation. Ann Neurol 2017;82:247-258. ..
  74. Mansouri F, Koechlin E, Rosa M, Buckley M. Managing competing goals - a key role for the frontopolar cortex. Nat Rev Neurosci. 2017;18:645-657 pubmed publisher
    ..Here, we argue that many other forms of uniquely human behaviour may benefit from this cognitive ability mediated by the frontopolar cortex. ..
  75. Taghipour Zahir S, Mortaz M, Baghi Yazdi M, Sefidrokh Sharahjin N, Shabani M. Calvarium mass as the first presentation of glioblastoma multiforme: A very rare manifestation of high-grade glioma. Neurochirurgie. 2018;64:76-78 pubmed publisher
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