Summary: The anterior subdivision of the embryonic PROSENCEPHALON or the corresponding part of the adult prosencephalon that includes the cerebrum and associated structures.

Top Publications

  1. Gohlke J, Stockton P, Sieber S, Foley J, Portier C. AhR-mediated gene expression in the developing mouse telencephalon. Reprod Toxicol. 2009;28:321-8 pubmed publisher modulated through an AhR-dependent interaction with key regulatory neuronal differentiation pathways during telencephalon development...
  2. Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S. MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011;31:3407-22 pubmed publisher
    ..that microRNA-9 (miR-9) controls neural progenitor proliferation and differentiation in the developing telencephalon by regulating the expression of multiple transcription factors...
  3. Rothenaigner I, Krecsmarik M, Hayes J, Bahn B, Lepier A, Fortin G, et al. Clonal analysis by distinct viral vectors identifies bona fide neural stem cells in the adult zebrafish telencephalon and characterizes their division properties and fate. Development. 2011;138:1459-69 pubmed publisher
    ..These results characterize fundamental aspects of adult progenitor cells and neurogenesis, and open the way to using virus-based technologies for stable genetic manipulations and clonal analyses in the zebrafish adult brain. ..
  4. García Moreno F, Pedraza M, Di Giovannantonio L, Di Salvio M, López Mascaraque L, Simeone A, et al. A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nuclei. Nat Neurosci. 2010;13:680-9 pubmed publisher
    ..The diencephalic transcription factor OTP was necessary for this migratory behavior. ..
  5. Caronia G, Wilcoxon J, Feldman P, Grove E. Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior. J Neurosci. 2010;30:6291-301 pubmed publisher
    ..mice that were deficient in Bmpr1b constitutively, and deficient in Bmpr1a conditionally in the dorsal telencephalon. In double mutant male and female mice, the dentate gyrus (DG) was dramatically smaller than in control mice, ..
  6. Maden M, Manwell L, Ormerod B. Proliferation zones in the axolotl brain and regeneration of the telencephalon. Neural Dev. 2013;8:1 pubmed publisher the ventricular zone of Urodeles spontaneously proliferate, producing progeny that migrate throughout the telencephalon before terminally differentiating into neurons...
  7. Hebert J, Fishell G. The genetics of early telencephalon patterning: some assembly required. Nat Rev Neurosci. 2008;9:678-85 pubmed publisher
    ..depends on the precise integration of specific neuronal subtypes that are born in different regions of the telencephalon. Here, using the mouse as a model system, we review how these proliferative zones are established...
  8. Costa S, Andrade R, Carneiro L, Gonçalves E, Kotrschal K, Oliveira R. Sex differences in the dorsolateral telencephalon correlate with home range size in blenniid fish. Brain Behav Evol. 2011;77:55-64 pubmed publisher
    ..Since the dorsolateral telencephalon has been considered a teleost homologue of the mammalian hippocampus, we predicted that the spatial abilities ..
  9. Charvet C, Striedter G. Developmental basis for telencephalon expansion in waterfowl: enlargement prior to neurogenesis. Proc Biol Sci. 2009;276:3421-7 pubmed publisher
    ..e. altricial) state, enlarged their telencephalon by delaying telencephalic neurogenesis. To determine whether species that hatch in a relatively mature (i.e...

More Information


  1. Zipancic I, Calcagnotto M, Piquer Gil M, Mello L, Alvarez Dolado M. Transplant of GABAergic precursors restores hippocampal inhibitory function in a mouse model of seizure susceptibility. Cell Transplant. 2010;19:549-64 pubmed publisher
  2. Salvante K, Racke D, Campbell C, Sockman K. Plasticity in singing effort and its relationship with monoamine metabolism in the songbird telencephalon. Dev Neurobiol. 2010;70:41-57 pubmed publisher
    ..Serotonin metabolism in the caudomedial mesopallium of the auditory telencephalon increased with the length of songs to which we exposed the subjects and with their singing effort...
  3. Fishell G, Rudy B. Mechanisms of inhibition within the telencephalon: "where the wild things are". Annu Rev Neurosci. 2011;34:535-67 pubmed publisher
    ..of the diversity and mechanisms by which GABAergic interneuron populations function in different parts of the telencephalon. This is followed by a summary of the mechanisms of inhibition in the CNS...
  4. Yamanishi E, Takahashi M, Saga Y, Osumi N. Penetration and differentiation of cephalic neural crest-derived cells in the developing mouse telencephalon. Dev Growth Differ. 2012;54:785-800 pubmed publisher
    ..differentiate into microvascular pericytes, but little is known about when and how cephalic NCDCs invade the telencephalon and differentiate into pericytes...
  5. Burmeister S, Munshi R, Fernald R. Cytoarchitecture of a cichlid fish telencephalon. Brain Behav Evol. 2009;74:110-20 pubmed publisher
    Although the telencephalon of ray-finned fishes has garnered considerable attention from comparative neuroanatomists, detailed descriptions of telencephalic organization are available for only a few species...
  6. Chen C, Winkler C, Pfenning A, Jarvis E. Molecular profiling of the developing avian telencephalon: regional timing and brain subdivision continuities. J Comp Neurol. 2013;521:3666-701 pubmed publisher
    ..These findings support the continuum hypothesis of avian brain subdivision development around the ventricle and influence hypotheses on homologies of the avian pallium with other vertebrates. ..
  7. Lado W, Zhang D, Mennigen J, Zamora J, Popesku J, Trudeau V. Rapid modulation of gene expression profiles in the telencephalon of male goldfish following exposure to waterborne sex pheromones. Gen Comp Endocrinol. 2013;192:204-13 pubmed publisher
    ..Both treatments elevated milt volume (P=0.001). Microarray analysis of male telencephalon following PGF2? treatment identified 71 unique transcripts that were differentially expressed (q<5%; 67 up, ..
  8. Ng M, Hsu C, Wu Y, Wu S, Yang Y, Lu K. Effect of MK-801-induced impairment of inhibitory avoidance learning in zebrafish via inactivation of extracellular signal-regulated kinase (ERK) in telencephalon. Fish Physiol Biochem. 2012;38:1099-1106 pubmed publisher
    ..These results suggest that the formation of long-term emotional memory is possibly mediated by ERK activation in the telencephalon of zebrafish.
  9. Durán E, Ocaña F, Gómez A, Jiménez Moya F, Broglio C, Rodriguez F, et al. Telencephalon ablation impairs goldfish allocentric spatial learning in a "hole-board" task. Acta Neurobiol Exp (Wars). 2008;68:519-25 pubmed
    The present work analyzes the involvement of telencephalon of goldfish in spatial strategies, using a procedure analogue to the hole-board task...
  10. Striedter G, Charvet C. Telencephalon enlargement by the convergent evolution of expanded subventricular zones. Biol Lett. 2009;5:134-7 pubmed publisher
    Some mammals and birds independently evolved an enlarged telencephalon. They appear to have done so, at least in part, by developing a thick telencephalic subventricular zone (SVZ)...
  11. Marteau L, Pacary E, Valable S, Bernaudin M, Guillemot F, Petit E. Angiopoietin-2 regulates cortical neurogenesis in the developing telencephalon. Cereb Cortex. 2011;21:1695-702 pubmed publisher
    ..Taken together, our results show for the first time that, in addition to its role during brain vasculature setup, Ang2 is also involved in embryonic cortical neurogenesis and especially in the radial migration of projection neurons. ..
  12. Tsubokawa T, Saito K, Kawano H, Kawamura K, Shinozuka K, Watanabe S. Pharmacological effects on mirror approaching behavior and neurochemical aspects of the telencephalon in the fish, medaka (Oryzias latipes). Soc Neurosci. 2009;4:276-86 pubmed publisher
    ..behavior and an immunohistochemical approach to examine the neurotransmitter distribution in the medaka telencephalon. In order to gain an insight into shoaling activity, we examined the pharmacological effects of the positive ..
  13. Rodriguez Moldes I. A developmental approach to forebrain organization in elasmobranchs: new perspectives on the regionalization of the telencephalon. Brain Behav Evol. 2009;74:20-9 pubmed publisher
    ..It is particularly crucial to understand the evolution of the telencephalon in chondrichthyans, as this structure develops by evagination (as in most other vertebrates), whereas in most ..
  14. Edelmann K, Glashauser L, Sprungala S, Hesl B, Fritschle M, Ninkovic J, et al. Increased radial glia quiescence, decreased reactivation upon injury and unaltered neuroblast behavior underlie decreased neurogenesis in the aging zebrafish telencephalon. J Comp Neurol. 2013;521:3099-115 pubmed publisher
    ..neurogenesis in the ventricular zone, in the olfactory bulb, and in a newly identified parenchymal zone of the telencephalon indeed declines as the fish ages and that oligodendrogenesis also declines...
  15. Langseth A, Munji R, Choe Y, Huynh T, Pozniak C, Pleasure S. Wnts influence the timing and efficiency of oligodendrocyte precursor cell generation in the telencephalon. J Neurosci. 2010;30:13367-72 pubmed publisher
    Oligodendrocyte precursor cells (OPCs) are generated from multiple progenitor domains in the telencephalon in developmental succession from ventral to dorsal...
  16. Matsunaga E, Nambu S, Oka M, Iriki A. Differential cadherin expression in the developing postnatal telencephalon of a New World monkey. J Comp Neurol. 2013;521:4027-60 pubmed publisher
    ..cadherins (Cdh4, -6, -7, -8, -9, -10, -11, -12, and -20) and T-cadherin (Cdh13)] in the developing postnatal telencephalon of the common marmoset (Callithrix jacchus)...
  17. Dizon M, SZELE F, Kessler J. Hypoxia-ischemia induces an endogenous reparative response by local neural progenitors in the postnatal mouse telencephalon. Dev Neurosci. 2010;32:173-83 pubmed publisher
    ..Thus, an endogenous regenerative oligodendroglial response to postnatal hypoxia-ischemia occurs locally, with minimal long-distance contribution by cells of the SVZ. ..
  18. Kawaguchi D, Yoshimatsu T, Hozumi K, Gotoh Y. Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalon. Development. 2008;135:3849-58 pubmed publisher
    ..evidence that the Notch-Delta pathway plays an important role in this selection in the developing mouse telencephalon. We found that the expression patterns of the Notch ligand delta-like 1 (Dll1) and of the active form of ..
  19. Nowakowski T, Mysiak K, Pratt T, Price D. Functional dicer is necessary for appropriate specification of radial glia during early development of mouse telencephalon. PLoS ONE. 2011;6:e23013 pubmed publisher
    ..for the generation of mature micro RNAs, by conditionally mutating the Dicer1 gene in the early embryonic telencephalon and analyse the molecular specification of radial glia as well as their progeny, namely postmitotic neurons ..
  20. Nieuwenhuys R. The forebrain of actinopterygians revisited. Brain Behav Evol. 2009;73:229-52 pubmed publisher
    ..Further, it is proposed that the lateral olfactory tract in teleosts, which supplies most of the olfactory fibers to Dp, is not homologous to the same-named tract in the inverted forebrains of most other vertebrates. ..
  21. Visel A, Taher L, Girgis H, May D, Golonzhka O, Hoch R, et al. A high-resolution enhancer atlas of the developing telencephalon. Cell. 2013;152:895-908 pubmed publisher
    The mammalian telencephalon plays critical roles in cognition, motor function, and emotion...
  22. Filby A, Paull G, Bartlett E, Van Look K, Tyler C. Physiological and health consequences of social status in zebrafish (Danio rerio). Physiol Behav. 2010;101:576-87 pubmed publisher
    ..The wide-ranging physiological differences seen between dominant and subordinate zebrafish as a consequence of their social status suggest negative health impacts for subordinates after prolonged durations in those hierarchies. ..
  23. Harvey Girard E, Tweedle J, Ironstone J, Cuddy M, Ellis W, Maler L. Long-term recognition memory of individual conspecifics is associated with telencephalic expression of Egr-1 in the electric fish Apteronotus leptorhynchus. J Comp Neurol. 2010;518:2666-92 pubmed publisher
    ..individual conspecifics based on complex sensory cues; this requires a large, highly differentiated dorsal telencephalon. Here we show that the electric fish Apteronotus leptorhynchus can learn to recognize individual conspecifics ..
  24. Imayoshi I, Sakamoto M, Yamaguchi M, Mori K, Kageyama R. Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains. J Neurosci. 2010;30:3489-98 pubmed publisher
    ..However, a requirement for Notch signaling in the telencephalon was not clear, because in Hes1;Hes3;Hes5 triple-mutant mice, neural stem/progenitor cells are depleted in most ..
  25. Sargeant T, Day D, Miller J, Steel R. Acute in utero morphine exposure slows G2/M phase transition in radial glial and basal progenitor cells in the dorsal telencephalon of the E15.5 embryonic mouse. Eur J Neurosci. 2008;28:1060-7 pubmed publisher
    ..5 mouse increases the length of the G(2)/M phase of the radial glial cell cycle in the dorsal telencephalon, as well as slows interkinetic nuclear migration of radial glial nuclei from the basal ventricular zone to the ..
  26. Nieuwenhuys R. The development and general morphology of the telencephalon of actinopterygian fishes: synopsis, documentation and commentary. Brain Struct Funct. 2011;215:141-57 pubmed publisher
    ..The telencephalon of actinopterygian fishes differs from that in all other vertebrates in that it consists of a pair of solid ..
  27. Ganz J, Kaslin J, Freudenreich D, Machate A, Geffarth M, Brand M. Subdivisions of the adult zebrafish subpallium by molecular marker analysis. J Comp Neurol. 2012;520:633-55 pubmed publisher
    The morphology of the telencephalon displays great diversity among different vertebrate lineages...
  28. Ayari B, El Hachimi K, Yanicostas C, Landoulsi A, Soussi Yanicostas N. Prokineticin 2 expression is associated with neural repair of injured adult zebrafish telencephalon. J Neurotrauma. 2010;27:959-72 pubmed publisher analyze the distribution of PROK2 transcripts in the adult zebrafish brain and during injury-induced telencephalon (TC) regeneration...
  29. März M, Chapouton P, Diotel N, Vaillant C, Hesl B, Takamiya M, et al. Heterogeneity in progenitor cell subtypes in the ventricular zone of the zebrafish adult telencephalon. Glia. 2010;58:870-88 pubmed publisher
    ..In the telencephalon, this complexity is enhanced by an organization of the ventricular zone (VZ) in fast and slow-dividing domains,..
  30. Flandin P, Kimura S, Rubenstein J. The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons. J Neurosci. 2010;30:2812-23 pubmed publisher
    ..Finally, our analysis provided evidence for a novel cellular component (Nkx2-1(-);Npas1(+)) of the globus pallidus. ..
  31. Shimogori T, Lee D, Miranda Angulo A, Yang Y, Wang H, Jiang L, et al. A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13:767-75 pubmed publisher
    ..Our results serve as a resource for functional investigations of hypothalamic development, connectivity, physiology and dysfunction. ..
  32. McPherson C, Mantamadiotis T, Tan S, Lawrence A. Deletion of CREB1 from the dorsal telencephalon reduces motivational properties of cocaine. Cereb Cortex. 2010;20:941-52 pubmed publisher
    ..We conclude that there is a specific role for CREB1 in telencephalic glutamatergic neurons regulating the motivational properties of cocaine. ..
  33. Suda Y, Kokura K, Kimura J, Kajikawa E, Inoue F, Aizawa S. The same enhancer regulates the earliest Emx2 expression in caudal forebrain primordium, subsequent expression in dorsal telencephalon and later expression in the cortical ventricular zone. Development. 2010;137:2939-49 pubmed publisher
    ..5, dorsal telencephalon at E9.5-E10.5 and the cortical ventricular zone after E12.5...
  34. Gil V, Bichler Z, Lee J, Seira O, Llorens F, Bribian A, et al. Developmental expression of the oligodendrocyte myelin glycoprotein in the mouse telencephalon. Cereb Cortex. 2010;20:1769-79 pubmed publisher
    ..Our data support the idea that early expressed MAIPs play an active role during development and point to OMgp participating in thalamo-cortical connections. ..
  35. März M, Schmidt R, Rastegar S, Strahle U. Regenerative response following stab injury in the adult zebrafish telencephalon. Dev Dyn. 2011;240:2221-31 pubmed publisher
    ..We analyzed the proliferation of glial cells and microglia in response to stab injury in the adult zebrafish telencephalon: Radial glial markers were up-regulated at the ventricle and co-expressed the proliferation nuclear antigen (..
  36. Baumgart E, Barbosa J, Bally Cuif L, Gotz M, Ninkovic J. Stab wound injury of the zebrafish telencephalon: a model for comparative analysis of reactive gliosis. Glia. 2012;60:343-57 pubmed publisher
    ..astrocytes, we examined the glial response to an invasive stab wound injury model in the adult zebrafish telencephalon. Strikingly, already a few days after injury the wound was closed without any scar tissue...
  37. Mulder J, Spence L, Tortoriello G, DiNieri J, Uhlen M, Shui B, et al. Secretagogin is a Ca2+-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon. Eur J Neurosci. 2010;31:2166-77 pubmed publisher
    ..that scgn may be expressed by particular neuronal contingents during prenatal development of the mammalian telencephalon. We find that scgn is expressed in neurons transiting in the subpallial differentiation zone by embryonic day (..
  38. Kim M, Habiba A, Doherty J, Mills J, Mercer R, Huettner J. Regulation of mouse embryonic stem cell neural differentiation by retinoic acid. Dev Biol. 2009;328:456-71 pubmed publisher
    ..Transcriptional profiling indicates a substantial representation of transit amplifying neuroblasts in SFD cultures not exposed to RA. ..
  39. März M, Schmidt R, Rastegar S, Strahle U. Expression of the transcription factor Olig2 in proliferating cells in the adult zebrafish telencephalon. Dev Dyn. 2010;239:3336-49 pubmed publisher
    The telencephalon of the adult zebrafish is highly proliferative: Dividing cells are found along the entire ventricular zone and in the parenchyma...
  40. Prajerova I, Honsa P, Chvatal A, Anderova M. Neural stem/progenitor cells derived from the embryonic dorsal telencephalon of D6/GFP mice differentiate primarily into neurons after transplantation into a cortical lesion. Cell Mol Neurobiol. 2010;30:199-218 pubmed publisher
    ..Therefore, region-specific D6/GFP-derived NSPCs represent a promising tool for studying neurogenesis and cell replacement in a damaged cellular environment. ..
  41. Folgueira M, Bayley P, Navratilova P, Becker T, Wilson S, Clarke J. Morphogenesis underlying the development of the everted teleost telencephalon. Neural Dev. 2012;7:32 pubmed publisher
    ..This is especially manifest in the telencephalon, where the most dramatic variation is seen between ray-finned fish, which have an everted telencephalon, and ..
  42. Park P, Bell M. Variation of telencephalon morphology of the threespine stickleback (Gasterosteus aculeatus) in relation to inferred ecology. J Evol Biol. 2010;23:1261-77 pubmed publisher
    We tested the hypothesis that increased telencephalon size has evolved in threespine stickleback fish (Gasterosteus aculeatus) from structurally complex habitats using field-caught samples from one sea-run (ancestral) and 18 ecologically ..
  43. Viktorin G, Chiuchitu C, Rissler M, Varga Z, Westerfield M. Emx3 is required for the differentiation of dorsal telencephalic neurons. Dev Dyn. 2009;238:1984-98 pubmed publisher
    ..Knockdown of Emx3 function by morpholino reduces the expression of markers specific to dorsal telencephalon, and impairs axon tract formation...
  44. Sylvester J, Rich C, Yi C, Peres J, Houart C, Streelman J. Competing signals drive telencephalon diversity. Nat Commun. 2013;4:1745 pubmed publisher
    The telencephalon is the most complex brain region, controlling communication, emotion, movement and memory. Its adult derivatives develop from the dorsal pallium and ventral subpallium...
  45. Shibata M, Kurokawa D, Nakao H, Ohmura T, Aizawa S. MicroRNA-9 modulates Cajal-Retzius cell differentiation by suppressing Foxg1 expression in mouse medial pallium. J Neurosci. 2008;28:10415-21 pubmed publisher
    ..Moreover, miR-9 overexpression in developing telencephalon at E11.5 by electroporation resulted in ectopic Reelin-positive cells over the cortex beyond the marginal zone...
  46. Kishimoto N, Shimizu K, Sawamoto K. Neuronal regeneration in a zebrafish model of adult brain injury. Dis Model Mech. 2012;5:200-9 pubmed publisher
    ..Recent studies show that neurogenesis in the ventricular zone (VZ) of the adult zebrafish telencephalon has features in common with neurogenesis in the adult mammalian SVZ...
  47. Manuel M, Martynoga B, Yu T, West J, Mason J, Price D. The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice. Development. 2010;137:487-97 pubmed publisher
    Foxg1 is required for development of the ventral telencephalon in the embryonic mammalian forebrain...
  48. Bielen H, Houart C. BMP signaling protects telencephalic fate by repressing eye identity and its Cxcr4-dependent morphogenesis. Dev Cell. 2012;23:812-22 pubmed publisher
    ..However, the molecular events driving the differential regionalization of this area into eye-field and telencephalon fates are still unknown...
  49. Wang B, Waclaw R, Allen Z, Guillemot F, Campbell K. Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon. Neural Dev. 2009;4:5 pubmed publisher
    ..Gsx2 (formerly Gsh2) is known to regulate patterning in the lateral ganglionic eminence (LGE) of the embryonic telencephalon. In its absence, the closely related gene Gsx1 (previously known as Gsh1) can partially compensate in the ..
  50. Hutton S, Pevny L. SOX2 expression levels distinguish between neural progenitor populations of the developing dorsal telencephalon. Dev Biol. 2011;352:40-7 pubmed publisher
    ..In the developing dorsal telencephalon, two distinct populations of neural progenitors, radial glia and intermediate progenitor cells, are ..
  51. Mueller T, Dong Z, Berberoglu M, Guo S. The dorsal pallium in zebrafish, Danio rerio (Cyprinidae, Teleostei). Brain Res. 2011;1381:95-105 pubmed publisher
    ..nicotine adenine dinucleotide phosphate diphorase (NADPHd) activity and parvalbumin in the anterior zebrafish telencephalon, we show that against previous assumptions the central (Dc) zone possesses its own germinative region in the ..
  52. Yaksi E, von Saint Paul F, Niessing J, Bundschuh S, Friedrich R. Transformation of odor representations in target areas of the olfactory bulb. Nat Neurosci. 2009;12:474-82 pubmed publisher
    ..This mechanism can extract information about combinations of molecular features from ensembles of active and inactive mitral cells, suggesting that pattern processing in Dp establishes representations of odor objects. ..
  53. Hernández Acosta N, Cabrera Socorro A, Morlans M, Delgado F, Suárez Solá M, Sottocornola R, et al. Dynamic expression of the p53 family members p63 and p73 in the mouse and human telencephalon during development and in adulthood. Brain Res. 2011;1372:29-40 pubmed publisher
    ..The p73 gene is relevant for brain development, and p73-deficient mice display important malformations of the telencephalon. In turn, p63 is essential for the development of stratified epithelia and may also play a part in neuronal ..
  54. Braford M. Stalking the everted telencephalon: comparisons of forebrain organization in basal ray-finned fishes and teleosts. Brain Behav Evol. 2009;74:56-76 pubmed publisher
    ..These hypotheses are evaluated and some persisting problems are enumerated. ..
  55. Garcia Calero E, Puelles L. Enc1 expression in the chick telencephalon at intermediate and late stages of development. J Comp Neurol. 2009;517:564-80 pubmed publisher
    In this work we studied the regional expression pattern of the Enc1 gene in the chick embryo telencephalon at intermediate and late stages of development, bearing on architectonic groupings and boundaries of current interest...
  56. Huillard E, Ziercher L, Blond O, Wong M, Deloulme J, Souchelnytskyi S, et al. Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol. 2010;30:2737-49 pubmed publisher
    ..Thus, CK2beta appears to play an essential and uncompensated role in central nervous system development. ..
  57. Chapouton P, Skupien P, Hesl B, Coolen M, Moore J, Madelaine R, et al. Notch activity levels control the balance between quiescence and recruitment of adult neural stem cells. J Neurosci. 2010;30:7961-74 pubmed publisher
    ..We use here the germinal zone of the zebrafish adult telencephalon to examine how the frequency of NSC divisions is regulated...
  58. Rudolph J, Zimmer G, Steinecke A, Barchmann S, Bolz J. Ephrins guide migrating cortical interneurons in the basal telencephalon. Cell Adh Migr. 2010;4:400-8 pubmed
    ..Together, these results suggest that ephrin-A3 acts as a repulsive cue that restricts cortical interneurons from entering inappropriate regions and thus contributes to define the migratory route of cortical interneurons. ..
  59. Wang Y, Brzozowska Prechtl A, Karten H. Laminar and columnar auditory cortex in avian brain. Proc Natl Acad Sci U S A. 2010;107:12676-81 pubmed publisher
    ..methods, we demonstrate the existence of comparable columnar functional modules in laminated auditory telencephalon of an avian species (Gallus gallus)...
  60. Gulacsi A, Anderson S. Beta-catenin-mediated Wnt signaling regulates neurogenesis in the ventral telencephalon. Nat Neurosci. 2008;11:1383-91 pubmed publisher
    Development of the telencephalon involves the coordinated growth of diversely patterned brain structures...
  61. Wu S, Esumi S, Watanabe K, Chen J, Nakamura K, Nakamura K, et al. Tangential migration and proliferation of intermediate progenitors of GABAergic neurons in the mouse telencephalon. Development. 2011;138:2499-509 pubmed publisher
    ..Therefore, they must migrate tangentially within the telencephalon to reach the neocortex...
  62. Castro D, Martynoga B, Parras C, Ramesh V, Pacary E, Johnston C, et al. A novel function of the proneural factor Ascl1 in progenitor proliferation identified by genome-wide characterization of its targets. Genes Dev. 2011;25:930-45 pubmed publisher
  63. Zhao T, Szabo N, Ma J, Luo L, Zhou X, Alvarez Bolado G. Genetic mapping of Foxb1-cell lineage shows migration from caudal diencephalon to telencephalon and lateral hypothalamus. Eur J Neurosci. 2008;28:1941-55 pubmed publisher
    ..The expanded neuroepithelium generates abundant neurons for the medial hypothalamus at the tuberal level. Finally, we have uncovered novel diencephalon-to-telencephalon migrations into septum, piriform cortex and amygdala.
  64. Carlin D, Sepich D, Grover V, Cooper M, Solnica Krezel L, Inbal A. Six3 cooperates with Hedgehog signaling to specify ventral telencephalon by promoting early expression of Foxg1a and repressing Wnt signaling. Development. 2012;139:2614-24 pubmed publisher
    ..can promote holoprosencephaly (HPE), a forebrain malformation that results, at least in part, from abnormal telencephalon development...
  65. Colasante G, Sessa A, Crispi S, Calogero R, Mansouri A, Collombat P, et al. Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity. Dev Biol. 2009;334:59-71 pubmed publisher
    The homeobox-containing gene Arx is expressed during ventral telencephalon development and required for correct GABAergic interneuron tangential migration from the ganglionic eminences to the olfactory bulbs, cerebral cortex and striatum...
  66. Sockman K, Ball G. Independent effects of song quality and experience with photostimulation on expression of the immediate, early gene ZENK (EGR-1) in the auditory telencephalon of female European starlings. Dev Neurobiol. 2009;69:339-49 pubmed publisher
    ..long songs over short songs in a mate-choice context, and, like that in other songbird species, their auditory telencephalon plays a major role in processing these signals...
  67. Roth M, Bonev B, Lindsay J, Lea R, Panagiotaki N, Houart C, et al. FoxG1 and TLE2 act cooperatively to regulate ventral telencephalon formation. Development. 2010;137:1553-62 pubmed publisher
    ..transcriptional repressor that plays a key role in the specification, proliferation and differentiation of the telencephalon, and is expressed from the earliest stages of telencephalic development through to the adult...
  68. Sørensen C, Bohlin L, Øverli Ø, Nilsson G. Cortisol reduces cell proliferation in the telencephalon of rainbow trout (Oncorhynchus mykiss). Physiol Behav. 2011;102:518-23 pubmed publisher
    ..rainbow trout in social hierarchies leads to a marked suppression of brain cell proliferation in the telencephalon, and that this is accompanied by an increase in plasma levels of cortisol...
  69. Yu W, Wang Y, McDonnell K, Stephen D, Bai C. Patterning of ventral telencephalon requires positive function of Gli transcription factors. Dev Biol. 2009;334:264-75 pubmed publisher
    ..However, whether Gli-mediated Shh signaling is also required to induce different cell types in the ventral telencephalon has been controversial...
  70. Kojima T, Hirota Y, Ema M, Takahashi S, Miyoshi I, Okano H, et al. Subventricular zone-derived neural progenitor cells migrate along a blood vessel scaffold toward the post-stroke striatum. Stem Cells. 2010;28:545-54 pubmed publisher
    ..These findings suggest that blood vessels play an important role as a scaffold for NPCs migration toward the damaged brain region. ..
  71. Ganz J, Kaslin J, Hochmann S, Freudenreich D, Brand M. Heterogeneity and Fgf dependence of adult neural progenitors in the zebrafish telencephalon. Glia. 2010;58:1345-63 pubmed publisher
    ..To understand the components of the progenitor zones in the adult zebrafish telencephalon and the link between glial characteristics and progenitor state, we examined whether canonical glial markers ..
  72. Yoshizawa A, Nakahara Y, Izawa T, Ishitani T, Tsutsumi M, Kuroiwa A, et al. Zebrafish Dmrta2 regulates neurogenesis in the telencephalon. Genes Cells. 2011;16:1097-109 pubmed publisher
    ..dmrta2 expression is restricted to the telencephalon, diencephalon and olfactory placode during somitogenesis...
  73. Nielsen J, Lau P, Maric D, Barker J, Hudson L. Integrating microRNA and mRNA expression profiles of neuronal progenitors to identify regulatory networks underlying the onset of cortical neurogenesis. BMC Neurosci. 2009;10:98 pubmed publisher
  74. Kishimoto N, Alfaro Cervello C, Shimizu K, Asakawa K, Urasaki A, Nonaka S, et al. Migration of neuronal precursors from the telencephalic ventricular zone into the olfactory bulb in adult zebrafish. J Comp Neurol. 2011;519:3549-65 pubmed publisher
    ..Taken together, our results suggest that the RMS in the adult zebrafish telencephalon is a functional migratory pathway...
  75. Lau B, Mathur P, Gould G, Guo S. Identification of a brain center whose activity discriminates a choice behavior in zebrafish. Proc Natl Acad Sci U S A. 2011;108:2581-6 pubmed publisher
    ..Based on these findings and previous connectivity data, we propose a neural circuitry model in which the Dm serves as a brain center, the activity of which predicates this choice behavior in zebrafish. ..
  76. Zhong J, Kim H, Lyu J, Yoshikawa K, Nakafuku M, Lu W. The Wnt receptor Ryk controls specification of GABAergic neurons versus oligodendrocytes during telencephalon development. Development. 2011;138:409-19 pubmed publisher
    GABAergic neurons and oligodendrocytes originate from progenitors within the ventral telencephalon. However, the molecular mechanisms that control neuron-glial cell-fate segregation, especially how extrinsic factors regulate cell-fate ..
  77. Takanaga H, Tsuchida Straeten N, Nishide K, Watanabe A, Aburatani H, Kondo T. Gli2 is a novel regulator of sox2 expression in telencephalic neuroepithelial cells. Stem Cells. 2009;27:165-74 pubmed publisher
    ..Thus these data reveal a novel transcriptional cascade, involving Gli2 --> Sox2 --> Hes5, which maintains the undifferentiated state of telencephalic NE cells. ..
  78. Danesin C, Peres J, Johansson M, Snowden V, Cording A, Papalopulu N, et al. Integration of telencephalic Wnt and hedgehog signaling center activities by Foxg1. Dev Cell. 2009;16:576-87 pubmed publisher
    ..Concomitantly to these roles, Foxg1 controls the formation of the compartment boundary between telencephalon and basal diencephalon...