post traumatic neoplasms

Summary

Summary: Tumors, cancer or other neoplasms caused by or resulting from trauma or other non-radiation injuries.

Top Publications

  1. Magee T, Rosenthal H. Skeletal muscle metastases at sites of documented trauma. AJR Am J Roentgenol. 2002;178:985-8 pubmed
    ..The hematomas and partial muscle tears were in the same skeletal muscle location in which the metastatic disease subsequently developed. Metastatic disease was documented by MR imaging and subsequent biopsy...
  2. Mohmand M, Yap L, Morris A. Neurothekeoma in a burned extremity. Plast Reconstr Surg. 2002;110:1186-7 pubmed
  3. Vernadakis A, Koch H, Mackinnon S. Management of neuromas. Clin Plast Surg. 2003;30:247-68, vii pubmed
  4. Kowal Vern A, Criswell B. Burn scar neoplasms: a literature review and statistical analysis. Burns. 2005;31:403-13 pubmed
    ..Excision and grafting of deep burns, and close follow-up of non-healing ulcerated burn scars is essential for the prevention and early detection of burn scar neoplasms. ..
  5. Mendonca D, Staiano J, Drew P. An unusual cutaneous neuroma following a burn injury. J Plast Reconstr Aesthet Surg. 2006;59:107 pubmed
  6. Nagata Y, Tomioka T, Chiba K, Kanematsu T. Traumatic neuroma of the common hepatic duct after laparoscopic cholecystectomy. Am J Gastroenterol. 1995;90:1887-8 pubmed
    ..Pathological examination showed that traumatic neuroma, probably caused by bile leakage after cauterization, led to stricture of the common bile duct...
  7. Mhoon J, Redman J, Siebert J. Scrotal enlargement in boys with a history of scrotal trauma: two unusual findings. South Med J. 2002;95:251-2 pubmed
    ..In the first case, there was bleeding from omentum in an incarcerated inguinal hernia, and in the second, there was bleeding into a scrotal cystic lymphangioma. Fewer than 40 cases of scrotal lymphangioma have been reported. ..
  8. Chong A, Klein M. Images in clinical medicine. Marjolin's ulcer. N Engl J Med. 2005;352:e9 pubmed
  9. Hill B, Sloan D, Lee E, McGrath P, Kenady D. Marjolin's ulcer of the foot caused by nonburn trauma. South Med J. 1996;89:707-10 pubmed
    ..Lymph node metastases and high tumor grade indicate a poor prognosis. Clinicians should be diligent in the long-term surveillance of all significant scars or areas of chronic inflammation. ..

More Information

Publications77

  1. Onah I, Olaitan P, Ogbonnaya I, Onuigbo W. Marjolin's ulcer (correction of ucler) at a Nigerian hospital (1993-2003). J Plast Reconstr Aesthet Surg. 2006;59:565-6 pubmed
  2. Carter R, Giudice C, Dubielzig R, Colitz C. Telomerase activity with concurrent loss of cell cycle regulation in feline post-traumatic ocular sarcomas. J Comp Pathol. 2005;133:235-45 pubmed publisher
    ..These findings suggest that p16, and not p53, represents the primary mechanism by which post-traumatic ocular sarcomas that express telomerase activity escape cell cycle control...
  3. Alcolado J, Ray K, Baxter M, Edwards C, Dodson P. Malignant change in dermatitis artefacta. Postgrad Med J. 1993;69:648-50 pubmed
    ..Recent literature concerning Marjolin's ulcers is reviewed and it is noted that this is the first reported case of death caused by malignant change in dermatitis artefacta. ..
  4. Schnirring Judge M, Visser J. Resection and reconstruction of an osteochondroma of the hallux: a review of benign bone tumors and a description of an unusual case. J Foot Ankle Surg. 2009;48:495-505 pubmed publisher
    ..We also report the case of a patient who experienced an unusual pedal digital osteochondroma-like lesion. 4. ..
  5. Scott J, Morris R, McPhaden A, Knight S, Webster M. Malignant schwannoma in a burn scar. Burns. 1996;22:494-6 pubmed
    ..The malignant potential of a burn scar is well recognized. Epidermal malignancies predominate and sarcomas are a rare finding. The first case of a malignant schwannoma developing in a burn scar is reported, and the management discussed. ..
  6. Ozyazgan I, Kontas O. Burn scar sarcoma. Burns. 1999;25:455-8 pubmed
    ..A case of fibrosarcoma developing in the burn scar was presented in this report and the literature reviewed. ..
  7. Rossi G, Marchioni A, Agostini L, Corradini P, Costantini M, Cavazza A. Traumatic neuroma of the bronchi: bronchoscopy and histology of a hitherto unreported lesion. Am J Surg Pathol. 2008;32:640-1 pubmed publisher
  8. Tanaka A, Hatoko M, Tada H, Kuwahara M, Iioka H, Niitsuma K. Dermatofibrosarcoma protuberans arising from a burn scar of the axilla. Ann Plast Surg. 2004;52:423-5 pubmed
    ..Two years after the operation, there was no evidence of tumor recurrence. As surgeons, we should recognize the possibility of the occurrence of various malignant tumors including sarcomas on burn scars. ..
  9. Leber G, Gosain A. Surgical excision of pedunculated supernumerary digits prevents traumatic amputation neuromas. Pediatr Dermatol. 2003;20:108-12 pubmed
    ..This treatment prevents traumatic amputation neuromas and yields a better cosmetic result than the traditional method of suture ligation in infancy. ..
  10. Asuquo M, Ikpeme I, Ebughe G, Bassey E. Marjolin's ulcer: Sequelae of mismanaged chronic cutaneous ulcers. Adv Skin Wound Care. 2010;23:414-6 pubmed publisher
    ..4 years. Chronic trauma-induced limb ulceration is the leading risk factor for Marjolin's ulcer. Health education, early detection, and proper management of chronic wounds would improve outcome. ..
  11. Kwon J, Ryu S, Kang Y. Traumatic neuroma around the celiac trunk after gastrectomy mimicking a nodal metastasis: a case report. Korean J Radiol. 2007;8:242-5 pubmed
    ..CT demonstrated the presence of a lobulated, homogeneous, hypoattenuating mass around the celiac trunk, mimicking a nodal metastasis. ..
  12. Calikapan G, Akan M, Karaca M, Akoz T. Marjolin ulcer of the scalp: intruder of a burn scar. J Craniofac Surg. 2008;19:1020-5 pubmed publisher
    ..A single huge scalp flap is often sufficient for soft tissue defects, and cranioplasty with methyl methacrylate is an appropriate option for reconstruction...
  13. Garcia Morales I, Pérez Gil A, Camacho F. [Marjolin's ulcer: burn scar carcinoma]. Actas Dermosifiliogr. 2006;97:529-32 pubmed
    ..We present the case of a 48-year-old male with squamous cell carcinoma on the old burn scar of legs that evolved favorably after excision...
  14. Janes S, Renaut P, Gordon M. Traumatic (or amputation) neuroma. ANZ J Surg. 2004;74:701-2 pubmed
  15. Galea L, Penington A, Morrison W. Post-traumatic pseudolipomas--a review and postulated mechanisms of their development. J Plast Reconstr Aesthet Surg. 2009;62:737-41 pubmed publisher
  16. McGonigal L, Riggs J, Schochet S, Ortiz O. Posttraumatic meningioma: explanation of an epidemiologic dichotomy. Mil Med. 1995;160:92-4 pubmed
    ..Although antecedent head trauma has been implicated as a risk factor for meningioma, epidemiological studies of this association have yielded divergent conclusions. An explanation for this epidemiologic dichotomy is suggested...
  17. Nishimoto S, Matsushita T, Matsumolo K, Adachi S. A rare case of burn scar malignancy. Burns. 1996;22:497-9 pubmed
    ..Histological findings indicated that the tumour was a pleomorphic liposarcoma. Amputation was performed, but he died 3 months after the operation. To our knowledge, this is only the second case of liposarcoma developing in a burn scar...
  18. Shanker V, Gadikoppula S, Loeffler M. Post traumatic osteoma of tibial insertion of medial collateral ligament of knee joint. Br J Sports Med. 1998;32:73-4 pubmed
    ..A comparison is made with Pellegrini Stieda disease, which is a similar affection of the femoral insertion of the medial ligament of the knee joint...
  19. Anbinder A, Paiva T, Mariano R, Quirino M. Traumatic neuroma of the lower lip. West Indian Med J. 2009;58:604-6 pubmed
    ..An excisional biopsy was performed and the final diagnosis was traumatic neuroma. After 18 months of follow-up, the patient is asymptomatic and there are no signs of recurrence...
  20. Lee J, Murphy S, Scanlon E. Effect of trauma on implantation of metastatic tumor in bone in mice. J Surg Oncol. 1994;56:178-84 pubmed
    ..These results suggest that the healing wound is a privileged site for experimental metastasis, particularly in the early stages. It is likely that the proteins in the blood clotting cascade are involved in local tumor implantation...
  21. Aust M, Spies M, Kall S, Gohritz A, Boorboor P, Kolokythas P, et al. Lipomas after blunt soft tissue trauma: are they real? Analysis of 31 cases. Br J Dermatol. 2007;157:92-9 pubmed
    ..A link between preceding blunt soft tissue trauma at the site of the tumour and the formation of lipomas has been described earlier. These soft tissue tumours have been named 'post-traumatic lipomas'...
  22. Sabin S, Goldstein G, Rosenthal H, Haynes K. Aggressive squamous cell carcinoma originating as a Marjolin's ulcer. Dermatol Surg. 2004;30:229-30 pubmed
    ..Marjolin's ulcer is an epidermoid carcinoma arising in a scar or chronic wound and can have an aggressive course...
  23. Menovsky T, Beek J, Weerman M, van Overbeeke J. Effect of a modified Nd:YAG laser technique on neuroma formation: An experimental study in rat sciatic nerve. Lasers Surg Med. 1999;25:213-8 pubmed
    ..This study was designed to evaluate whether the neodymium:yttrium aluminum garnet (Nd:YAG) laser could prevent neuroma formation after neurectomy...
  24. Kotulska K, Larysz Brysz M, Marcol W, Grajkowska W, Jozwiak S, Lewin Kowalik J. The role of trkB receptor in the formation of post-traumatic neuroma. Folia Neuropathol. 2006;44:221-7 pubmed
    ..We also noticed many more mast cells accumulated at the surgery site in trkB-deficient than in wild-type animals. These results indicate the important role of BDNF receptor in post-traumatic neuroma formation...
  25. Garzon R, Burgos E, GARZON F, Cippitelli L, de Cabalier E, Cabalier L. [Marjolin ulcer]. Rev Fac Cien Med Univ Nac Cordoba. 2001;58:93-7 pubmed
    ..Sometimes they appear after 50 years of the previous accident. Three patients showing squamous cell epitheliomas are presented, and the opportunity and technique of the surgical treatment is discussed...
  26. Cohen S, Ad El D, Benjaminov O, Gutman H. Post-traumatic soft tissue tumors: case report and review of the literature a propos a post-traumatic paraspinal desmoid tumor. World J Surg Oncol. 2008;6:28 pubmed publisher
    ..Several criteria have been established to define a cause-and-effect relationship. We postulate possible mechanisms in the genesis of soft tissue tumors following antecedent traumatic injury...
  27. Love R, Breidahl A. Acute squamous cell carcinoma arising within a recent burn scar in a 14-year-old boy. Plast Reconstr Surg. 2000;106:1069-71 pubmed
    ..The authors recommend early skin grafting of deep partial- and full-thickness burns to prevent future malignant transformation and a low index of suspicion of any nodules or ulceration appearing within a healed burn...
  28. Hopkins J, Rayan G. Osteolipoma of the hand: a case report. J Okla State Med Assoc. 1999;92:535-7 pubmed
    ..Surgical excision of the lesion revealed a lipoma overlying a bony exostosis or osteolipoma of the hand. Post-operatively, the patient's symptoms resolved and she had no recurrence of the tumor...
  29. Nachtwey B, Rogiers X, Waldstroem J, Malago M, Nicolas V, Guthoff A, et al. Hilar traumatic neuroma after liver transplantation. Transpl Int. 1997;10:157-60 pubmed
    ..Moreover, intimal hyperplasia of the hepatic artery was present. Retransplantation was necessary because the hepatic artery was not salvageable. Potential pathophysiological mechanisms for these findings are discussed...
  30. Cheng C, Southwick E, Lewis E. Aneurysms of the superficial temporal artery: literature review and case reports. Ann Plast Surg. 1998;40:668-71 pubmed
    ..This is the first report of a preoperative diagnosis of STA aneurysm that subsequently proved incorrect...
  31. Agale S, Kulkarni D, Valand A, Zode R, Grover S. Marjolin's ulcer--a diagnostic dilemma. J Assoc Physicians India. 2009;57:593-4 pubmed
    ..We report a case of Marjolin's ulcer arising in a post-traumatic chronic ulcer of sole in a 60-year-old female...
  32. Gattuso P, Candel A, Castelli M, Kowal Vern A, Gamelli R, Herman C. Pseudoepitheliomatous hyperplasia in chronic cutaneous wounds. A flow cytometric study. J Cutan Pathol. 1994;21:312-5 pubmed
    ..Aneuploidy was present in 9.3% of the PH cases studied. SCC may arise from a subgroup of PH in a background of rapidly proliferating keratinocytes...
  33. Huang L, Weissman J, Fan C. Traumatic neuroma after neck dissection: CT characteristics in four cases. AJNR Am J Neuroradiol. 2000;21:1676-80 pubmed
    ..The purpose of this study was to identify CT characteristics of traumatic neuroma in four patients after neck dissection...
  34. Emsen I. A great Marjolin's ulcer of the scalp invading outer calvarial bone and its different treatment with support of Medpor. J Craniofac Surg. 2008;19:1026-9 pubmed publisher
  35. Colina F, García Prats M, Moreno E, Garcia Muñoz H, Ballestin C, Mayordomo J, et al. Amputation neuroma of the hepatic hilum after orthotopic liver transplantation. Histopathology. 1994;25:151-7 pubmed
    ..There was only one symptomatic patient, who died from extrahepatic cholestasis demonstrated at autopsy to be caused by a hilar neuroma obstructing the main bile duct...
  36. Merzenich H, Ahrens W, Stang A, Baumgardt Elms C, Jahn I, Stegmaier C, et al. Sorting the hype from the facts in testicular cancer: is testicular cancer related to trauma?. J Urol. 2000;164:2143-4 pubmed
    ..A population based, multicenter case-control study was performed from 1995 to 1997 to investigate potential risk factors for gonadal and extragonadal germ cell cancer...
  37. Rico Aguado A, Holguín Holgado P, Cárcamo Hermoso C, Poblet E. Exuberant granulation tissue mimicking vascular tumours associated with burns. Burns. 1995;21:383-6 pubmed
    ..We discuss the clinical and histological differential diagnosis of the case presented: a disseminated variant of lobular capillary haemangioma, Kaposi's sarcoma, bacillary angiomatosis and hyperplastic granulation tissue...
  38. Diaz Hernandez M, Febles G, Domínguez del Toro M, Reboso Morales L, Llopart López J, Gambra Michel L. [A recurrent desmoid tumor of the popliteal fossa with vascular compromise]. Angiologia. 1993;45:131-4 pubmed
    ..The research for 8 years and 4 months doesn't show any relapse, nor local neither multicentral. Furthermore, some considerations about this theme are reported...
  39. Aboulafia A, Littelton K, Shmookler B, Malawer M. Malignant fibrous histiocytoma at the site of hip replacement in association with chronic infection. Orthop Rev. 1994;23:427-32 pubmed
    ..The authors urge development of a tumor registry to discover if the association between hip replacement and malignancy is coincidental...
  40. Chai J, Sheng Z, Guo Z. [Carcinoma arising from postburn scars (report of 5 cases)]. Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi. 1994;10:183-5 pubmed
    ..On the contrary, the number of Langerhan's cells were smallest in cancer area, as compared with PEH and normal skin. The diagnosis, treatment and prevention of such malignant degeneration in postburn scars have been discussed...
  41. Reid D, Ngo H, Lamarche J. Primary post-traumatic intraorbital meningioma. J Otolaryngol. 1994;23:298-301 pubmed
    ..We report a case of primary post-traumatic intraorbital meningioma and discuss its pathogenesis and management...
  42. Cobey F, Engrav L, Klein M, Isom C, Byrd D. Brief report: sentinel lymph node dissection and burn scar carcinoma sentinel node and burn scar carcinoma. Burns. 2008;34:271-4 pubmed
  43. Gadhia K, Rehman K, Williams R, Sharp I. Traumatic pseudolipoma: herniation of buccal fat pad, a report of two cases. Int J Oral Maxillofac Surg. 2009;38:694-6 pubmed publisher
    ..This injury is rare, but two cases presented to the authors' hospital over a period of 3 months...
  44. Hatzis G, Finn R. Marjolin's ulcer: a review of the literature and report of a unique patient treated with a CO(2) laser. J Oral Maxillofac Surg. 2007;65:2099-105 pubmed
  45. Gressner O, Saurbruch T. Embryonal rhabdomyosarcoma secondary to an open fracture of the tibia: a case report and review of literature. South Med J. 2008;101:99-101 pubmed publisher
    ..The affected leg was amputated. The patient refused adjuvant chemotherapy and one year after surgery remains disease-free and in good general condition...
  46. Cocke W, Tomlinson J. Malignant fibrous histiocytoma developing in burn scar of the ear. Burns. 1993;19:241-3 pubmed
    ..Metastases can occur in 50 per cent of patients. This patient represents a rare and previously unreported presentation of malignant fibrous histiocytoma in a burn scar of the ear...
  47. Hensel K, Ono C, Doukas W. Squamous cell carcinoma in chronic ulcerative lesions: a case report and literature review. Am J Orthop (Belle Mead NJ). 1999;28:253-6 pubmed
    ..The case presented is a reminder of the need to maintain a high index of suspicion for malignant transformation within ulcerative lesions...
  48. Matsuoka J, Tanaka N, Kojima K, Takai K, Hamaya K, Gochi A, et al. A case of traumatic neuroma of the gallbladder in the absence of previous surgery and cholelithiasis. Acta Med Okayama. 1996;50:273-7 pubmed
    ..This traumatic neuroma should be considered in a differential diagnosis in treating gallbladder neoplasm, even in the absence of an operative history or cholelithiasis...
  49. de Roos K, Neumann H. Traumatic neuroma. A rare complication following Muller's phlebectomy. J Dermatol Surg Oncol. 1994;20:681-2 pubmed
    ..Complications following ambulatory surgical phlebectomy are rare, and to our knowledge, traumatic neuromas have never been reported...
  50. Kakinoki R, Ikeguchi R, Atiyya A, Nakamura T. Treatment of posttraumatic painful neuromas at the digit tip using neurovascular island flaps. J Hand Surg Am. 2008;33:348-52 pubmed publisher
    ..We report the treatment of 9 patients with 9 painful neuromas at the tips of the digits using reverse pedicled island flaps containing subcutaneous nerves that were connected to the digital nerve stumps after removal of the neuromas...
  51. Spagnoli A, Costanzo Egheoni G, Monacelli G, Agha Bigli A, Capua A. [Post-traumatic subperiosteal chondroma of the hand. Clinical case]. Minerva Chir. 1995;50:313-6 pubmed
    ..No erosion of the bone cortex could be observed radiographically. The development of the tumor appears to follow a violent trauma without skeletal lesions occurred seven months before...
  52. Uysal A, Kocer U, Sungur N, Cologlu H, Kankaya Y, Ulusoy M, et al. Marjolin's ulcer on frostbite. Burns. 2005;31:792-4 pubmed
  53. Rahimizadeh A, Shelton R, Weinberg H, Sadick N. The development of a Marjolin's cancer in a human immunodeficiency virus-positive hemophilic man and review of the literature. Dermatol Surg. 1997;23:560-3 pubmed
    ..Furthermore, it has been reported that human immunodeficiency virus (HIV)-positive patients have a higher incidence of basal cell carcinoma (BCC) than the general population...
  54. Chantranuwat C, Shuangshoti S. Traumatic neuroma as a cause of obstructive jaundice. J Med Assoc Thai. 1999;82:619-22 pubmed
    ..Despite rarity, traumatic neuroma of the bile duct should be considered in patients who have antecedent surgical procedure of the biliary tract with subsequent occurrence of extrahepatic biliary obstruction...
  55. Copcu E, Culhaci N. Marjolin's ulcer on the nose. Burns. 2002;28:701-4 pubmed
    ..The case was managed by tumor excision and a naso-labial transposition flap. To our knowledge, this is the first report of Marjolin's ulcer developing on post-burned skin of the nose...
  56. Glockner J, Sundaram M, White L. Incidence of solitary soft-tissue metastases revealed by MR imaging. AJR Am J Roentgenol. 2002;179:1644; author reply 1644 pubmed
  57. Normand J, Rioux M, Dumont M, Bouchard G, Letourneau L. Thoracic splenosis after blunt trauma: frequency and imaging findings. AJR Am J Roentgenol. 1993;161:739-41 pubmed
    ..The aim of this prospective study was to evaluate the prevalence of thoracic splenosis in 17 subjects who had sustained splenic and diaphragmatic injury and to describe the CT and MR features of thoracic splenosis...
  58. Adil A, Hoeffel C, Fikry T. Osteoid osteoma after a fracture of the distal radius. AJR Am J Roentgenol. 1996;167:145-6 pubmed
    ..We report a case of osteoid osteoma occurring at the site of a previous fracture of the radius treated by internal fixation with insertion of a rod. The fracture may have acted as a trigger for the formation of an osteoid osteoma...
  59. Coy J. Combat injury with chronic osteomyelitis complicated by squamous cell carcinoma. Mil Med. 1994;159:665-7 pubmed
    ..The patient described in this paper sustained such an injury in Vietnam. He exhibited the frequent complication of chronic osteomyelitis and eventually the rare complication of squamous cell carcinoma...
  60. Martin J, Monteagudo C, Alonso V, Llombart B, de la Fuente C, Garcia L, et al. Basal cell carcinomas arising on a skin graft secondary to a thermal burn scar. Burns. 2005;31:789-91 pubmed
  61. Lee E, Calcaterra T, Zuckerbraun L. Traumatic neuromas of the head and neck. Ear Nose Throat J. 1998;77:670-4, 676 pubmed
    ..Knowledge of this possible diagnosis may spare the patient and the surgeon needless worry, as well as unnecessary procedures, once tumor recurrence has been ruled out...
  62. Chen K, Lee K, Hsu H, Huang W, Hsiao K, Fang K. The role of high-resolution ultrasound in the diagnosis of a traumatic neuroma in an injured median nerve. Am J Phys Med Rehabil. 2009;88:771-4 pubmed publisher
    ..Postoperatively, the patient's symptoms improved significantly. This case suggests that high-resolution ultrasound may be superior to electrodiagnostic studies for the diagnosis of traumatic neuroma...
  63. Phillips T, Salman S, Bhawan J, Rogers G. Burn scar carcinoma. Diagnosis and management. Dermatol Surg. 1998;24:561-5 pubmed
    ..The term Marjolin ulcer is now synonymous with malignant transformation of chronic ulcers, sinus tracts, and burn scars...
  64. Smidt L, Smidt L, Chedid M, Bavaresco C, Chedid M. Radical surgical treatment for Marjolin ulcer occurring after chronic osteomyelitis. South Med J. 2005;98:1053 pubmed
  65. Aydogdu E, Yildirim S, Akoz T. Is surgery an effective and adequate treatment in advanced Marjolin's ulcer?. Burns. 2005;31:421-31 pubmed
    ..An aggressive combined approach is essential for treatment in early stages with high success rate. But there is no consensus for the treatment of advanced disease and results are generally unsuccessful...
  66. Christenson L, Stone M. Trauma-induced simulator of targetoid hemosiderotic hemangioma. Am J Dermatopathol. 2001;23:221-3 pubmed
    ..This case is remarkable for its unusual clinical presentation, histologic simulation of THH, and for its support for the theory that trauma can induce the histologic changes seen in THH...
  67. Zhang Y, Chen X, Liu Y, Zhang L. [Trauma and tumor: a report of 14 cases]. Fa Yi Xue Za Zhi. 1997;13:9-11, 64 pubmed
    ..In the present article, we report 14 cases of patients with different tumors, injured or died after a traumatic episode. The relation between trauma and tumor, and the associated problems in forensic medicine are discussed...
  68. Balakrishnan C, Noorily M, Prasad J, Wilson R. Metastatic adenocarcinoma in a recent burn scar. Burns. 1994;20:371-2 pubmed
    ..Nevertheless we recently treated a patient with a metastatic adenocarcinoma from the lung in a 3-month-old burn scar...