neoplasm seeding

Summary

Summary: The local implantation of tumor cells by contamination of instruments and surgical equipment during and after surgical resection, resulting in local growth of the cells and tumor formation.

Top Publications

  1. Bessa X, Castells A, Lacy A, Elizalde J, Delgado S, Boix L, et al. Laparoscopic-assisted vs. open colectomy for colorectal cancer: influence on neoplastic cell mobilization. J Gastrointest Surg. 2001;5:66-73 pubmed
    ..These results confirm that preoperative and perioperative mobilization of neoplastic cells is a frequent occurrence in patients with colorectal cancer, but the surgical approach (LAC vs. OC) does not seem to be a determining factor...
  2. Barber A, Lowe D, Lal S, Rogers S. Survey of gastrostomy insertion technique used in oncology patients in UK oral and maxillofacial units. J Craniomaxillofac Surg. 2010;38:60-3 pubmed publisher
    ..Gastrostomy site seeding was estimated to have occurred in only 5% of units over a 3 year period...
  3. Cappell M. Risk factors and risk reduction of malignant seeding of the percutaneous endoscopic gastrostomy track from pharyngoesophageal malignancy: a review of all 44 known reported cases. Am J Gastroenterol. 2007;102:1307-11 pubmed
    ..To comprehensively review all known reported cases of stomal metastases after percutaneous endoscopic gastrostomy (PEG) to systematically identify risk factors for this complication and to develop strategies for reducing this risk...
  4. Hagemann I, Hagemann A, LiVolsi V, Montone K, Chu C. Risk of occult malignancy in morcellated hysterectomy: a case series. Int J Gynecol Pathol. 2011;30:476-83 pubmed publisher
    ..Even with a complete workup, however, morcellation of occult uterine malignancy remains a possibility. This risk should be discussed as part of informed consent before morcellation...
  5. Robertson E, Baxter G. Tumour seeding following percutaneous needle biopsy: the real story!. Clin Radiol. 2011;66:1007-14 pubmed publisher
    ..Conclusions have been derived from an extensive analysis of the published literature, and a number of key recommendations should assist practitioners in their everyday practice...
  6. Podsypanina K, Du Y, Jechlinger M, Beverly L, Hambardzumyan D, Varmus H. Seeding and propagation of untransformed mouse mammary cells in the lung. Science. 2008;321:1841-4 pubmed publisher
    ..Mammary cells lacking oncogenic transgenes displayed a similar capacity for long-term residence in the lungs but did not form ectopic tumors...
  7. Silva M, Hegab B, Hyde C, Guo B, Buckels J, Mirza D. Needle track seeding following biopsy of liver lesions in the diagnosis of hepatocellular cancer: a systematic review and meta-analysis. Gut. 2008;57:1592-6 pubmed publisher
    ..The incidence of needle track seeding following biopsy of a suspicious liver lesion is ill-defined, however...
  8. Chatni S, Betigeri A, Sadasivan S, Nair P, Narayanan V, Balakrishanan V. Education and imaging. Gastrointestinal: abdominal wall metastasis after percutaneous endoscopic gastrostomy. J Gastroenterol Hepatol. 2008;23:988 pubmed publisher
  9. Al Leswas D, O Reilly D, Poston G. Biopsy of solid liver tumors: adverse consequences. Hepatobiliary Pancreat Dis Int. 2008;7:325-7 pubmed
    ..While it has an undoubted role in the investigation and management of acute and chronic inflammatory conditions of the liver, its role in hepatic oncology is doubtful and probably dangerous...

More Information

Publications81

  1. Siddiqi A, Hamilton R, Minocha A. Malignant seeding of percutaneous endoscopic gastrostomy tract in patient with head and neck cancer. Am J Med Sci. 2008;336:291-2 pubmed publisher
    ..As such, we also provide pictures that would help the health care providers recognize this rare entity and manage appropriately and promptly...
  2. Takeda A, Mori M, Sakai K, Mitsui T, Nakamura H. Parasitic peritoneal leiomyomatosis diagnosed 6 years after laparoscopic myomectomy with electric tissue morcellation: report of a case and review of the literature. J Minim Invasive Gynecol. 2007;14:770-5 pubmed
    ..Pathological examination demonstrated that these tumors were progesterone receptor-positive leiomyomas that were almost identical histologically to the myoma tissue excised 6 years earlier...
  3. Cucinella G, Granese R, Calagna G, Somigliana E, Perino A. Parasitic myomas after laparoscopic surgery: an emerging complication in the use of morcellator? Description of four cases. Fertil Steril. 2011;96:e90-6 pubmed publisher
    ..To report the development of parasitic myomas after the use of a morcellator...
  4. Lin H, Ibrahim H, Kheng J, Fee W, Terris D. Percutaneous endoscopic gastrostomy: strategies for prevention and management of complications. Laryngoscope. 2001;111:1847-52 pubmed
    ..We review our experience with PEG focusing on the complications as well as strategies for the prevention and management of these complications...
  5. Lacy A, Delgado S, Garcia Valdecasas J, Castells A, Pique J, Grande L, et al. Port site metastases and recurrence after laparoscopic colectomy. A randomized trial. Surg Endosc. 1998;12:1039-42 pubmed
    ..This study was performed to prospectively assess the impact of the laparoscopic approach to the patterns of port site metastases (PSM) and recurrence rate (RR) of resected colon carcinomas as compared with conventional colectomies...
  6. Coletti D, Genuit T, Ord R, Engroff S. Metastasis to the percutaneous endoscopic gastrostomy site in the patient with head and neck cancer: a case report and review of the literature. J Oral Maxillofac Surg. 2006;64:1149-57 pubmed
  7. Cruz I, Mamel J, Brady P, Cass Garcia M. Incidence of abdominal wall metastasis complicating PEG tube placement in untreated head and neck cancer. Gastrointest Endosc. 2005;62:708-11; quiz 752, 753 pubmed
    ..Abdominal wall metastasis after PEG tube placement has been reported in patients with head and neck cancer. The incidence of this occurrence is unknown...
  8. Micames C, Jowell P, White R, Paulson E, Nelson R, Morse M, et al. Lower frequency of peritoneal carcinomatosis in patients with pancreatic cancer diagnosed by EUS-guided FNA vs. percutaneous FNA. Gastrointest Endosc. 2003;58:690-5 pubmed
    ..EUS-FNA is an alternate method of diagnosis. The aim of this study was to compare the frequency of peritoneal carcinomatosis as a treatment failure pattern in patients with pancreatic cancer diagnosed by EUS-FNA vs. percutaneous FNA...
  9. Agostini A, Robin F, Aggerbeck M, Jais J, Blanc B, Lecuru F. Influence of peritoneal factors on port-site metastases in a xenograft ovarian cancer model. BJOG. 2001;108:809-12 pubmed
    ..We determine the main physical effects of pneumoperitoneum on tumour dissemination and port-site metastases occurrence...
  10. Espinoza S, Briggs P, Duret J, Lapeyre M, de Baere T. Radiofrequency ablation of needle tract seeding in hepatocellular carcinoma. J Vasc Interv Radiol. 2005;16:743-6 pubmed
    ..Percutaneous radiofrequency ablation of such seeding is one elegant potential treatment option. Efficacy seems promising but has to be confirmed in larger series. Further evaluation is needed...
  11. Thakore J, Mustafa M, Suryaprasad S, Agrawal S. Percutaneous endoscopic gastrostomy associated gastric metastasis. J Clin Gastroenterol. 2003;37:307-11 pubmed
    ..The mechanism of gastric metastasis in patients with PEG is unclear. Seeding as well as hematogenous and lymphatic spread to traumatized tissue may be the cause...
  12. Kurdow R, Schniewind B, Delere Y, Boehle A, Luttges J, Doniec J. Implantation metastasis of a hypopharyngeal carcinoma at the site of a percutaneous endoscopic gastrostomy. Endoscopy. 2003;35:462 pubmed
  13. Ananth S, Amin M. Implantation of oral squamous cell carcinoma at the site of a percutaneous endoscopic gastrostomy: a case report. Br J Oral Maxillofac Surg. 2002;40:125-30 pubmed
    ..We review the relevant publications and discuss the techniques, complications and possible mechanisms of spread and their implications for the use of percutaneous endoscopic gastrostomy in head and neck cancer surgery...
  14. Arrive L, Vurgait A, Monnier Cholley L, Lewin M, Balladur P, Poupon R, et al. Long-term follow-up after neoplastic seeding complicating percutaneous ethanol injection for treatment of hepatocellular carcinoma. Eur Radiol. 2002;12:74-6 pubmed
    ..One should pay attention to the abdominal wall around the needle track in interpreting CT or MR images of patients with previous PEI...
  15. Sinclair J, Scolapio J, Stark M, Hinder R. Metastasis of head and neck carcinoma to the site of percutaneous endoscopic gastrostomy: case report and literature review. JPEN J Parenter Enteral Nutr. 2001;25:282-5 pubmed
    ..However, metastasis of the original tumor to the gastrostomy exit site may occur...
  16. Takahashi H, Konishi M, Nakagohri T, Inoue K, Takahashi S, Tanizawa Y, et al. Aggressive multimodal treatment for peritoneal dissemination and needle tract implantation of hepatocellular carcinoma: a case report. Jpn J Clin Oncol. 2004;34:551-5 pubmed
  17. Jaskolka J, Asch M, Kachura J, Ho C, Ossip M, Wong F, et al. Needle tract seeding after radiofrequency ablation of hepatic tumors. J Vasc Interv Radiol. 2005;16:485-91 pubmed
    ..To determine the incidence and risk factors associated with needle tract seeding after radiofrequency ablation (RFA) of liver tumors...
  18. Lane G, Tay J. Port-site metastasis following laparoscopic lymphadenectomy for adenosquamous carcinoma of the cervix. Gynecol Oncol. 1999;74:130-3 pubmed
    ..This report adds to the literature suggesting that cutaneous tumor deposition may be enhanced by this method of surgery...
  19. Tarantino L, Francica G, Esposito F, Pisaniello D, Parmeggiani D, Marzullo G, et al. Seeding from hepatocellular carcinoma after percutaneous ablation: color Doppler ultrasound findings. Abdom Imaging. 2006;31:69-77 pubmed
    ..We describe the clinical and color Doppler ultrasound findings in a series of cases of seeding from hepatocellular carcinoma (HCC) observed in patients treated with percutaneous ablation therapy (PAT) over a 15-year period...
  20. Mincheff T. Metastatic spread to a percutaneous gastrostomy site from head and neck cancer: case report and literature review. JSLS. 2005;9:466-71 pubmed
    ..A potential complication of percutaneous endoscopic gastrostomy tubes is the metastatic spread from the original head and neck tumor to the gastrostomy site...
  21. Carlson N, Krivak T, Winter W, Macri C. Port site metastasis of ovarian carcinoma remote from laparoscopic surgery for benign disease. Gynecol Oncol. 2002;85:529-31 pubmed
    ..However, as we continue to realize the benefits and expand the scope of laparoscopic procedures, new complications may occur...
  22. Maturen K, Nghiem H, Marrero J, Hussain H, Higgins E, Fox G, et al. Lack of tumor seeding of hepatocellular carcinoma after percutaneous needle biopsy using coaxial cutting needle technique. AJR Am J Roentgenol. 2006;187:1184-7 pubmed
    ..Reported seeding rates range from 0.6% to 5.1% using various biopsy techniques. To our knowledge, the rate of seeding using a coaxial cutting needle technique has not been reported...
  23. Liu Y, Chen C, Chen Y, Wang C, Wang S, Lin C. Needle tract implantation of hepatocellular carcinoma after fine needle biopsy. Dig Dis Sci. 2007;52:228-31 pubmed
    ..The patients who do need a biopsy should be carefully followed up for early detection of implanted tumor and its recurrence after resection...
  24. Chang S, Kim S, Lim H, Lee W, Choi D, Lim J. Needle tract implantation after sonographically guided percutaneous biopsy of hepatocellular carcinoma: evaluation of doubling time, frequency, and features on CT. AJR Am J Roentgenol. 2005;185:400-5 pubmed
  25. Jones O, Rees M, John T, Bygrave S, Plant G. Biopsy of resectable colorectal liver metastases causes tumour dissemination and adversely affects survival after liver resection. Br J Surg. 2005;92:1165-8 pubmed
    ..Liver resection is increasingly being performed for metastatic colorectal cancer. This study assessed the need for preoperative biopsy of suspected metastases and whether biopsy has any effect on long-term survival...
  26. Iemsawatdikul K, Gooding C, Twomey E, Kim G, Goldsby R, Cohen I, et al. Seeding of osteosarcoma in the biopsy tract of a patient with multifocal osteosarcoma. Pediatr Radiol. 2005;35:717-21 pubmed
    ..We report a case of multifocal osteosarcoma in a 7-year-old boy who developed iatrogenic seeding of tumor along the biopsy tract. The results of the plain radiograph, CT, and histopathological correlation are presented...
  27. Bergstrom M, Falk P, Holmdahl L. CO2 promotes plasminogen activator inhibitor type 1 expression in human mesothelial cells. Surg Endosc. 2003;17:1818-22 pubmed
    ..Previous observations have indicated that CO2 insufflation increases peritoneal plasminogen activator inhibitor type 1 (PAI-1) expression...
  28. Rodgers M, Collinson R, Desai S, Stubbs R, McCall J. Risk of dissemination with biopsy of colorectal liver metastases. Dis Colon Rectum. 2003;46:454-8; discussion 458-9 pubmed
    ..To date, only case reports describing this problem have been published. This study is an attempt to quantify the risk of biopsy-related dissemination...
  29. Pickhardt P, Rohrmann C, Cossentino M. Stomal metastases complicating percutaneous endoscopic gastrostomy: CT findings and the argument for radiologic tube placement. AJR Am J Roentgenol. 2002;179:735-9 pubmed
    ..Cumulative data from previous case reports are also considered for insight into causes of metastasis and the implications for gastrostomy placement in these patients...
  30. Shoup M, Brennan M, Karpeh M, Gillern S, McMahon R, Conlon K. Port site metastasis after diagnostic laparoscopy for upper gastrointestinal tract malignancies: an uncommon entity. Ann Surg Oncol. 2002;9:632-6 pubmed
    ..This study was designed to examine the incidence of port site metastasis and open incision site metastasis for upper gastrointestinal tract (GI) malignancies...
  31. Durand F, Regimbeau J, Belghiti J, Sauvanet A, Vilgrain V, Terris B, et al. Assessment of the benefits and risks of percutaneous biopsy before surgical resection of hepatocellular carcinoma. J Hepatol. 2001;35:254-8 pubmed
    ..This study was aimed at determining the usefulness, accuracy and safety of this technique as well as the incidence of needle tract seeding...
  32. Llovet J, Vilana R, Bru C, Bianchi L, Salmeron J, Boix L, et al. Increased risk of tumor seeding after percutaneous radiofrequency ablation for single hepatocellular carcinoma. Hepatology. 2001;33:1124-9 pubmed
    ..Iatrogenic dissemination was related to subcapsular location or an invasive tumoral pattern, and has to be considered when selecting curative treatments for HCC or adjuvant therapies before liver transplantation...
  33. Neuhaus S, Watson D, Ellis T, Dodd T, Rofe A, Jamieson G. Efficacy of cytotoxic agents for the prevention of laparoscopic port-site metastases. Arch Surg. 1998;133:762-6 pubmed
    ..This study investigated in an experimental model the influence of cytotoxic agents (administered intraperitoneally or intramuscularly) on the development of port-site metastases following laparoscopic surgery...
  34. Jilani G, Mohamed D, Wadia H, Ramzi K, Meriem J, Houssem L, et al. Cutaneous metastasis of renal cell carcinoma through percutaneous fine needle aspiration biopsy: case report. Dermatol Online J. 2010;16:10 pubmed
    ..This case represents an unusual clinical presentation of metastatic renal cell carcinoma that appears to have been translocated to the skin by the needle biopsy...
  35. Levy M, Heimbach J, Gores G. Endoscopic ultrasound staging of cholangiocarcinoma. Curr Opin Gastroenterol. 2012;28:244-52 pubmed publisher
    ..An emerging indication for EUS is the diagnosis and staging of cholangiocarcinoma. This information may be used to help guide patient care and improve outcomes, but may also be employed in a manner that risks patient well being. ..
  36. Vallancien G, Cathelineau X, Barret E, Rozet F. [Laparoscopic surgery in urologic oncology]. Bull Acad Natl Med. 2007;191:1367-73; discussion 1373-4 pubmed
    ..Provided the general rules of oncologic surgery are respected, laparoscopy is safe and effective in the management of urological malignancies. ..
  37. Imahiyerobo Ip J, Wartman D, Brennick J, Chapman M. Unknown: a warm, painful nodule on the back. Dermatol Online J. 2012;18:9 pubmed
    ..Diagnosis of metastatic SCC secondary to traumatic seeding at a trocar port site was made. To our knowledge, this has not been previously described in the literature. ..
  38. Sugarbaker P. Improving oncologic outcomes for colorectal cancer at high risk for local-regional recurrence with novel surgical techniques. Expert Rev Gastroenterol Hepatol. 2016;10:205-13 pubmed publisher
    ..Data regarding novel surgical techniques that include perioperative cancer chemotherapy to provide more optimal treatment are described. The perioperative timing of the revised surgical options is emphasized. ..
  39. Lovrics P, Goldsmith C, Hodgson N, McCready D, Gohla G, Boylan C, et al. A multicentered, randomized, controlled trial comparing radioguided seed localization to standard wire localization for nonpalpable, invasive and in situ breast carcinomas. Ann Surg Oncol. 2011;18:3407-14 pubmed publisher
    ..In contrast to other trials positive margin and reoperation rates were similar for RSL and WL. However, for RSL operative times were shorter, and the technique was preferred by surgeons, making it an acceptable method for localization. ..
  40. Sartori C, D Annibale A, Cutini G, Senargiotto C, D Antonio D, Dal Pozzo A, et al. Laparoscopic surgery for colorectal cancer: clinical practice guidelines of the Italian Society of Colo-Rectal Surgery. Tech Coloproctol. 2007;11:97-104 pubmed
  41. Ellrichmann M, Sergeev P, Bethge J, Arlt A, Topalidis T, Ambrosch P, et al. Prospective evaluation of malignant cell seeding after percutaneous endoscopic gastrostomy in patients with oropharyngeal/esophageal cancers. Endoscopy. 2013;45:526-31 pubmed publisher
    ..This risk is particularly high in the older age group and in patients with higher tumor stages. Therefore, pull-through PEG placement should be avoided in these patients and direct access PEG favored instead. ..
  42. Stem J, Haupt H. Reexcision perineural invasion. Am J Dermatopathol. 2007;29:221 pubmed
  43. Chang C, Chang Y, Lee Y. Cystic malignant teratoma with early recurrence after intraoperative spillage. Ann Thorac Surg. 2008;86:1971-3 pubmed publisher
    ..The rapid tumor dissemination was postoperatively noted. Careful and complete resection with the cyst wall of the mediastinal mature cystic teratoma intact is necessary to avoid a risk of relapse from a potentially malignant component. ..
  44. Chang Qing F, Yi L, DE Guang W, Qing Bin S, Xiang Min H, Na T, et al. Immune clearance gastric carcinoma cells in ascites by activating caspase-9-induced apoptosis. APMIS. 2011;119:173-9 pubmed publisher
    ..05) than those with high caspase-9 expression. These findings suggest that immune clearance gastric carcinoma cells in ascites activated by caspase-9 helped to improve the prognosis of patients with gastric cancer. ..
  45. Goetze T, Paolucci V. Use of retrieval bags in incidental gallbladder cancer cases. World J Surg. 2009;33:2161-5 pubmed publisher
    ..047) prognostic disadvantage and in these cases retrieval bags were used more often (P = 0.001). However, in IGBC cases if intraoperative gallbladder perforation has already happened, the use of retrieval bags had no protective effects. ..
  46. Cramer S. Reexcision perineural invasion. Am J Dermatopathol. 2007;29:221; author reply 221-2 pubmed
  47. Riker D, Sell R. Ultrasound-guided percutaneous biopsy to diagnose indwelling pleural catheter metastasis. J Bronchology Interv Pulmonol. 2012;19:165-7 pubmed publisher
    ..We report the use of ultrasound-guided percutaneous biopsy to diagnose metastatic seeding of an IPC. ..
  48. Hasegawa K, Matsumoto R, Yamada H, Kuroda T, Mamiya Y, Kon A. [A case of sigmoid colon carcinoma accompanied with hydronephrosis caused by peritoneal dissemination and para-aortic lymph node metastases markedly responded to chemotherapy]. Gan To Kagaku Ryoho. 2009;36:2213-6 pubmed
    ..Sigmoidectomy was done in the beginning of February 2009, dissemination disappeared completely. Histologically, most mucinous carcinoma cells disappeared or denatured, with viable tumor cells slightly remained. ..
  49. Volpe A, Terrone C, Scarpa R. The current role of percutaneous needle biopsies of renal tumours. Arch Ital Urol Androl. 2009;81:107-12 pubmed
    ..Finally, there is potential for stratifying initial therapy of metastatic RCC by histological subtype on needle biopsies. ..
  50. Guihaire J, Verhoye J, De Latour B, Leguerrier A. Parietal tumor recurrence of lung metastasis after radiofrequency ablation. Interact Cardiovasc Thorac Surg. 2010;10:650-1 pubmed publisher
    ..This case highlights the risk of iatrogenic parietal contamination after RFA. To our knowledge no similar case has been published to date. The most appropriate steps to prevent this type of complication still have to be defined. ..
  51. Takahashi Y, Nagino M, Nishio H, Ebata T, Igami T, Nimura Y. Percutaneous transhepatic biliary drainage catheter tract recurrence in cholangiocarcinoma. Br J Surg. 2010;97:1860-6 pubmed publisher
    ..The aim of the study was to clarify the incidence, risk factors and treatment of percutaneous transhepatic biliary drainage (PTBD) catheter tract recurrence in patients with resected cholangiocarcinoma...
  52. Ofluoglu O, Donthineni R. Iatrogenic seeding of a giant cell tumor of the patella to the proximal tibia. Clin Orthop Relat Res. 2007;465:260-4 pubmed
    ..The cause and prevention of implantation metastasis are discussed and the basic principles of musculoskeletal tumor management emphasized. ..
  53. Velnar T, Bunc G. Iatrogenic metastasis of a benign meningioma to the periosteum at the site of previous craniotomy: a case report. Wien Klin Wochenschr. 2008;120:766-9 pubmed publisher
    ..The authors suggest that strict adherence to oncological principles should be applied in the case of benign neoplasms in order to prevent contamination of wounds with tumor cells and potential recurrence...
  54. Neill M, Dixon P. Effects of a preincisional 14-day course of valerian on natural killer cell activity in Sprague-Dawley male rats undergoing abdominal surgery. Holist Nurs Pract. 2007;21:187-93 pubmed
    ..It has been demonstrated that benzodiazepines may ameliorate surgery-induced suppression of NK cell activity. We examined the effect of a 14-day course of valerian, a herbal anxiolytic, on NK cell activity in Sprague-Dawley rats...
  55. Janes S, Rahman N, Davies R, Lee Y. Catheter-tract metastases associated with chronic indwelling pleural catheters. Chest. 2007;131:1232-4 pubmed
    ..7% of 45 patients treated with indwelling pleural catheters for malignant pleural effusions. Both clinicians and patients should be aware of this potential complication...
  56. Mahore A, Chagla A, Goel A. Seeding metastases of a benign intraventricular meningioma along the surgical track. J Clin Neurosci. 2010;17:253-5 pubmed publisher
    ..We report a patient with a benign fibroblastic intraventricular meningioma that had spread along the path of previous surgery; the recurrences as well as the primary tumor were benign...
  57. Azlan C, Mohd Nasir N, Saifizul A, Faizul M, Ng K, Abdullah B. A low cost solution for post-biopsy complications using available RFA generator and coaxial core biopsy needle. Australas Phys Eng Sci Med. 2007;30:288-91 pubmed
    ..We also found that the solution proposed provides a low cost and practical way to minimizes unwanted post-biopsy effects...
  58. Tywończuk Szulc M, Kibiłda B. [Malignant melanoma of the auditory tube]. Otolaryngol Pol. 2007;61:335-8 pubmed
    ..The patient was under constant laryngologic and oncological observation. We did not notice the local recurrence of melanoma. She died two years after making the diagnosis because of the neoplasm dissemination...
  59. Stigliano R, Marelli L, Yu D, Davies N, Patch D, Burroughs A. Seeding following percutaneous diagnostic and therapeutic approaches for hepatocellular carcinoma. What is the risk and the outcome? Seeding risk for percutaneous approach of HCC. Cancer Treat Rev. 2007;33:437-47 pubmed
    ..Although percutaneous therapy whether with or without biopsy of a suspected HCC nodule may minimize the risk of seeding, this has not been confirmed...
  60. Dondossola E, Crippa L, Colombo B, Ferrero E, Corti A. Chromogranin A regulates tumor self-seeding and dissemination. Cancer Res. 2012;72:449-59 pubmed publisher
    ..Inhibition of the multidirectional trafficking of cancer cells in normal and neoplastic tissues may represent a novel strategy to reduce cancer progression...
  61. Ng J. Is on-table rectal stump washout necessary?. ANZ J Surg. 2007;77:1028-9 pubmed
  62. Woopen H, Pietzner K, Darb Esfahani S, Oskay Oezcelik G, Sehouli J. Extraperitoneal response to intraperitoneal immunotherapy with catumaxomab in a patient with cutaneous lymphangiosis carcinomatosa from ovarian cancer: a case report and review of the literature. Med Oncol. 2012;29:3416-20 pubmed publisher
    ..Even though response of extraperitoneal tumor sites can be explained with intravascular uptake and a possible vaccination effect, this phenomenon has not been reported up to this point to the best of our knowledge...
  63. Furukawa M, Izumi S, Asano H, Tokumo M, Mano S, Shiota K. Late umbilical port-site recurrence of a gastrointestinal stromal tumor with an acquired PDGFR? mutation after laparoscopic resection: report of a case. Surg Laparosc Endosc Percutan Tech. 2012;22:e109-11 pubmed publisher
    ..To date, only 4 cases of port-site recurrence after laparoscopic resection of GIST have been reported. This is the first study to report an acquired PDGFR? mutation in port-site recurrence after laparoscopic resection of a GIST...
  64. Shan L, Wang Z, Yue Y. Uterine sarcoma with abdominal wall metastasis following laparoscopy: case report. Eur J Gynaecol Oncol. 2011;32:590-1 pubmed
    ..This work aimed to prevent artificial implantation in laparoscopic surgery for gynecological tumors...
  65. Shields C, Ghassemi F, Tuncer S, Thangappan A, Shields J. Clinical spectrum of diffuse infiltrating retinoblastoma in 34 consecutive eyes. Ophthalmology. 2008;115:2253-8 pubmed publisher
    ..To evaluate the clinical features and management of diffuse infiltrating retinoblastoma...
  66. Quenet F, Goere D, Mehta S, Roca L, Dumont F, Hessissen M, et al. Results of two bi-institutional prospective studies using intraperitoneal oxaliplatin with or without irinotecan during HIPEC after cytoreductive surgery for colorectal carcinomatosis. Ann Surg. 2011;254:294-301 pubmed publisher
    ..To assess the perioperative and long-term results of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) using oxaliplatin+irinotecan (ox-irino) versus oxaliplatin alone (ox-alone)...
  67. Smith S, Pulido J, Salomao D, Smith B, Mohney B. Combined intravitreal and subconjunctival carboplatin for retinoblastoma with vitreous seeds. Br J Ophthalmol. 2012;96:1073-7 pubmed publisher
    ..To describe the technique of intravitreal chemotherapy preceded by subconjunctival chemotherapy for the treatment of vitreous seeds in advanced stage retinoblastoma...
  68. Barbulescu M, Alecu L, Boeti P, Popescu I. Port-site metastasis after laparoscopic surgery for colorectal cancer--still a real concern? Case report and review of the literature. Chirurgia (Bucur). 2012;107:103-7 pubmed
    ..The operations were performed at the Center of Digestive Diseases and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania, between 1st January 2002 and 31st december 2008. There was only one case of PMS (0.81%)...
  69. Greco F, Wagner S, Reichelt O, Inferrera A, Lupo A, Hoda R, et al. Huge isolated port-site recurrence after laparoscopic partial nephrectomy: a case report. Eur Urol. 2009;56:737-9 pubmed publisher
    ..The patient underwent open surgery, which confirmed the diagnosis. After the operation, the patient recovered rapidly...
  70. Kim J, Choi Y, Kim J, Gil W, Nam S, Oh Y, et al. Thyroid cancer that developed around the operative bed and subcutaneous tunnel after endoscopic thyroidectomy via a breast approach. Surg Laparosc Endosc Percutan Tech. 2008;18:197-201 pubmed publisher
    ..Herein, we present a case of 25-year-old woman who had recurrent cancers around the operative bed and subcutaneous tunnel after endoscopic thyroidectomy...
  71. Matsuzaki S, Bourdel N, Darcha C, Dechelotte P, Bazin J, Pouly J, et al. Molecular mechanisms underlying postoperative peritoneal tumor dissemination may differ between a laparotomy and carbon dioxide pneumoperitoneum: a syngeneic mouse model with controlled respiratory support. Surg Endosc. 2009;23:705-14 pubmed publisher
    ..The mechanisms promoting postoperative peritoneal tumor dissemination are unclear. This study aimed to investigate postoperative tumor dissemination over time on both tissue and molecular levels...
  72. Yen C, Lee C, Murk W, Han C, Liao S. Reducing peritoneal vascular endothelial growth factor concentration and inhibiting cancer scattering in a mouse model of laparoscopy. Am J Obstet Gynecol. 2008;198:423.e1-7 pubmed publisher
    ..p.) paclitaxel administration in reducing vascular endothelial growth factor (VEGF) concentration in peritoneal fluid and preventing intraoperative cancer scattering during laparoscopy...