sweat gland neoplasms

Summary

Summary: New abnormal growth of tissue in the SWEAT GLANDS.

Top Publications

  1. Hiatt K, Pillow J, Smoller B. Her-2 expression in cutaneous eccrine and apocrine neoplasms. Mod Pathol. 2004;17:28-32 pubmed
    ..Finally, this study suggests that HER-2 protein expression can be a useful tool in differentiating a primary cutaneous appendageal neoplasm from HER-2 expressing metastatic breast carcinoma...
  2. Nicolino R, Zalaudek I, Ferrara G, Annese P, Giorgio C, Moscarella E, et al. Dermoscopy of eccrine poroma. Dermatology. 2007;215:160-3 pubmed
    ..We report 2 patients with EP and discuss the diagnostic significance of the observed dermoscopic findings...
  3. Brown C, Dy L. Eccrine porocarcinoma. Dermatol Ther. 2008;21:433-8 pubmed publisher
    ..MMS affords the greatest likelihood of clear margins and cure in absence of regional and distant metastases...
  4. Jain R, Prabhakaran V, Huilgol S, Gehling N, James C, Selva D. Eccrine porocarcinoma of the upper eyelid. Ophthalmic Plast Reconstr Surg. 2008;24:221-3 pubmed publisher
    ..We describe a 70-year-old man who was examined for right upper eyelid eccrine porocarcinoma that was treated with Mohs surgery. Eccrine porocarcinoma should be considered in the differential diagnosis of malignant eyelid tumors...
  5. Jin W, Kim G, Lew B, Yang D, Kim H, Ryu J, et al. Sonographic findings of an eccrine spiradenoma: case report and literature review. J Ultrasound Med. 2008;27:813-8 pubmed
  6. Chang O, Elnawawi A, Rimpel B, Asarian A, Chaudhry N. Eccrine porocarcinoma of the lower extremity: a case report and review of literature. World J Surg Oncol. 2011;9:94 pubmed publisher
    ..The initial tumor was biopsied, excised and diagnosed as an eccrine poroma. The tumor then recurred 6 years later, was re-excised, reconstructed with a soleus muscle flap and diagnosed as an eccrine porocarcinoma...
  7. Ohi Y, Umekita Y, Rai Y, Kukita T, Sagara Y, Sagara Y, et al. Clear cell hidradenoma of the breast: a case report with review of the literature. Breast Cancer. 2007;14:307-11 pubmed
    ..These features were consistent with clear cell hidradenoma...
  8. Gerber P, Schulte K, Ruzicka T, Bruch Gerharz D. Eccrine porocarcinoma of the head: an important differential diagnosis in the elderly patient. Dermatology. 2008;216:229-33 pubmed publisher
    ..Instead, eccrine porocarcinoma frequently occurs on the lower extremities, trunk and abdomen, but also on the head, resembling various other skin tumors, as illustrated in the patients described herein...
  9. Hu S, Chen G, Wu C, Chai C, Chen W, Lan C. Pigmented eccrine poromas: expression of melanocyte-stimulating cytokines by tumour cells does not always result in melanocyte colonization. J Eur Acad Dermatol Venereol. 2008;22:303-10 pubmed publisher
    ..Although eccrine poroma (EP) occurs preferentially in palmoplantar areas, pigmented variants of EP have not been documented on the palms and soles...

More Information

Publications62

  1. Robson A, Lazar A, Ben Nagi J, Hanby A, Grayson W, Feinmesser M, et al. Primary cutaneous apocrine carcinoma: a clinico-pathologic analysis of 24 cases. Am J Surg Pathol. 2008;32:682-90 pubmed publisher
    ..Furthermore, steroid receptor expression should be investigated in these tumors, particularly if a tumor is unlikely to be controlled by surgery alone...
  2. Minagawa A, Koga H. Dermoscopy of pigmented poromas. Dermatology. 2010;221:78-83 pubmed publisher
    ..To date, little is known about the dermoscopic features of pigmented poromas...
  3. Mortensen A, Heegaard S, Clemmensen O, Prause J. Signet ring cell carcinoma of the eyelid - the monocle tumour. APMIS. 2008;116:326-32 pubmed publisher
    ..A diagnosis of primary signet ring cell carcinoma was made in both cases. Histopathological, immunohistological and ultrastructural findings indicated that the tumours were of sweat gland origin...
  4. Mulinari Brenner F, Mukai M, Bastos C, Filho E, Santamaria J, Neto J. [Eccrine porocarcinoma: report of four cases and literature review]. An Bras Dermatol. 2009;84:519-23 pubmed
    ..Two biopsies were described as eccrine poroma. Malignancy was observed in all cases after wide excision. Therefore, eccrine porocarcinoma should always be considered after a biopsy compatible with eccrine poroma...
  5. Mahomed F, Blok J, Grayson W. The squamous variant of eccrine porocarcinoma: a clinicopathological study of 21 cases. J Clin Pathol. 2008;61:361-5 pubmed
    ..This study describes the clinical and pathological findings in a series of 21 cases of EPC showing extensive squamous differentiation...
  6. Shiohara J, Koga H, Uhara H, Takata M, Saida T. Eccrine porocarcinoma: clinical and pathological studies of 12 cases. J Dermatol. 2007;34:516-22 pubmed
    ..Death was correlated with a pathological growth pattern and clinical lymph node metastasis. Sentinel lymph node biopsy was performed usefully in two patients...
  7. Mullaney P, Becker E, Graham B, Ghazarian D, Riddell R, Salonen D. Benign hidradenoma: magnetic resonance and ultrasound features of two cases. Skeletal Radiol. 2007;36:1185-90 pubmed
    ..The imaging literature of this tumor is reviewed, and its significance is discussed with respect to the current understanding of its malignant potential...
  8. Kazakov D, Bisceglia M, Calonje E, Hantschke M, Kutzner H, Mentzel T, et al. Tubular adenoma and syringocystadenoma papilliferum: a reappraisal of their relationship. An interobserver study of a series, by a panel of dermatopathologists. Am J Dermatopathol. 2007;29:256-63 pubmed
  9. de Giorgi V, Sestini S, Massi D, Papi F, Lotti T. Eccrine porocarcinoma: a rare but sometimes fatal malignant neoplasm. Dermatol Surg. 2007;33:374-7 pubmed
  10. Lee J, Chang J, Lee K. Syringoma: a clinicopathologic and immunohistologic study and results of treatment. Yonsei Med J. 2007;48:35-40 pubmed
    ..006). We also performed immunohistochemical stain for the presence of progesterone receptor (PR) and estrogen receptor (ER) in fifty six cases with negative results...
  11. Avilés Izquierdo J, Velázquez Tarjuelo D, Lecona Echevarría M, Lazaro Ochaita P. [Dermoscopic features of eccrine poroma]. Actas Dermosifiliogr. 2009;100:133-6 pubmed
    ..The lesions were characterized by multiple red lacunes and a polymorphous vascular pattern in both cases. Dermoscopy can improve the clinical diagnosis of this benign adnexal skin tumor...
  12. Han Y, Huan Y, Deng J, Zhang Y, Zhang C. MRI appearance of multiple eccrine spiradenoma. Br J Radiol. 2007;80:e27-9 pubmed
    ..Although the signal intensities of the lesions were not characteristic in this patient, multiple eccrine spiradenoma should be included in the differential diagnosis of the lesions in the cutis and the subcutaneous tissue...
  13. Soler Carrillo J, Estrach T, Mascaro J. Eruptive syringoma: 27 new cases and review of the literature. J Eur Acad Dermatol Venereol. 2001;15:242-6 pubmed
    ..Eruptive syringomas are uncommon eccrine sweat gland tumours. Only 64 cases have been reported in the literature...
  14. Bleier B, Newman J, Quon H, Feldman M, Kent K, Weinstein G. Eccrine porocarcinoma of the nose: case report and review of world literature. Arch Otolaryngol Head Neck Surg. 2006;132:215-8 pubmed
  15. Vandeweyer E, Renorte C, Musette S, Gilles A. Eccrine porocarcinoma: a case report. Acta Chir Belg. 2006;106:121-3 pubmed
    ..Here we present the case of a 64-year-old female patient with a small reddish nodule of the knee that, on histological evaluation, proved to be an eccrine porocarcinoma...
  16. Obaidat N, Awamleh A, Ghazarian D. Adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma of the peri-anal region. Eur J Dermatol. 2006;16:576-8 pubmed
    ..To the best of our knowledge, this is the first description of a peri-anal adenocarcinoma in situ arising in a tubulopapillary apocrine hidradenoma. The relationship to MLGs is also discussed...
  17. Busam K, Tan L, Granter S, Kohler S, Junkins Hopkins J, Berwick M, et al. Epidermal growth factor, estrogen, and progesterone receptor expression in primary sweat gland carcinomas and primary and metastatic mammary carcinomas. Mod Pathol. 1999;12:786-93 pubmed
    ..001). The frequencies of expression of ER and PR in SGCs and BCs metastatic to skin were not significantly different...
  18. Akalin T, Sen S, Yuceturk A, Kandiloglu G. P53 protein expression in eccrine poroma and porocarcinoma. Am J Dermatopathol. 2001;23:402-6 pubmed
    ..P53 gene may involve in the carcinogenetic pathway of porocarcinoma but it is likely that other oncogenes may also have a role...
  19. Robson A, Greene J, Ansari N, Kim B, Seed P, McKee P, et al. Eccrine porocarcinoma (malignant eccrine poroma): a clinicopathologic study of 69 cases. Am J Surg Pathol. 2001;25:710-20 pubmed
    ..We also suggest that tumors presenting an "infiltrative" advancing margin are particularly prone to local recurrence and require wide excision with close attention to the surgical margins by the reporting pathologist...
  20. Wildemore J, Lee J, Humphreys T. Mohs surgery for malignant eccrine neoplasms. Dermatol Surg. 2004;30:1574-9 pubmed
    ..With the exception of microcystic adnexal carcinoma (MAC), there have been few reports on the use of Mohs micrographic surgery (MMS) as a primary treatment for EC...
  21. Klenzner T, Arapakis I, Kayser G, Boedeker C. Eccrine porocarcinoma of the ear mimicking basaloid squamous cell carcinoma. Otolaryngol Head Neck Surg. 2006;135:158-60 pubmed
  22. Iwao F, Onozuka T, Kawashima T. Vulval syringoma successfully treated with tranilast. Br J Dermatol. 2005;153:1228-30 pubmed
  23. Eckert F, Betke M, Schmoeckel C, Neuweiler J, Schmid U. Myoepithelial differentiation in benign sweat gland tumors. Demonstrated by a monoclonal antibody to alpha-smooth muscle actin. J Cutan Pathol. 1992;19:294-301 pubmed
    ..In contrast, myoepithelial cells are absent in tumors showing differentiation toward the excretory (ductal) component of the gland...
  24. Urso C, Bondi R, Paglierani M, Salvadori A, Anichini C, Giannini A. Carcinomas of sweat glands: report of 60 cases. Arch Pathol Lab Med. 2001;125:498-505 pubmed
    ..Several aspects of sweat gland carcinomas (incidence, classification, diagnosis, and behavior) have not been definitively clarified and need to be studied further...
  25. Mirza I, Kloss R, Sieber S. Malignant eccrine spiradenoma. Arch Pathol Lab Med. 2002;126:591-4 pubmed
    ..Wide local excision and close follow-up are crucial in the management of malignant eccrine spiradenoma. The role of other therapeutic modalities, including hormonal therapy, remains to be determined...
  26. Aktepe F, Demir Y, Dilek F. Tubular apocrine adenoma in association with syringocystadenoma papilliferum. Dermatol Online J. 2003;9:7 pubmed
    ..It was difficult to distinguish stromal cells and epithelial cells from each other in some areas. The characteristics and differences in histopathologic and immunohistochemical findings in these tumors are described...
  27. Bogner P, Fullen D, Lowe L, Paulino A, Biermann J, Sondak V, et al. Lymphatic mapping and sentinel lymph node biopsy in the detection of early metastasis from sweat gland carcinoma. Cancer. 2003;97:2285-9 pubmed
    ..In the current study, the authors demonstrated the utility of SLN biopsy in detecting subclinical metastases of sweat gland carcinoma, which may result in early treatment...
  28. Ohta M, Hiramoto M, Fujii M, Togo T. Nodular hidradenocarcinoma on the scalp of a young woman: case report and review of literature. Dermatol Surg. 2004;30:1265-8 pubmed
    ..Several synonyms and related terms for nodular hidradenocarcinoma have appeared in the literature...
  29. Ghai S, Bukhanov K. Eccrine acrospiroma of breast: mammographic and ultrasound findings. Clin Radiol. 2004;59:1142-4 pubmed
  30. Wollensak G, Witschel H, Bohm N. Signet ring cell carcinoma of the eccrine sweat glands in the eyelid. Ophthalmology. 1996;103:1788-93 pubmed
    ..Signet ring cell carcinoma of the eyelid is a rare variant of eccrine sweat gland carcinoma and has been reported previously in only five patients...
  31. Stokes J, Ironside J, Smith C, Dhillon B. Tubular apocrine adenoma--an unusual eyelid tumour. Eye (Lond). 2005;19:237-9 pubmed
  32. Kamiya H, Oyama Z, Kitajima Y. "Apocrine" poroma: review of the literature and case report. J Cutan Pathol. 2001;28:101-4 pubmed
    ..quot;Apocrine" poroma has recently been proposed as a new term to designate a distinctive benign skin neoplasm with differentiation toward the folliculosebaceous-apocrine unit...
  33. Obaidat N, Alsaad K, Ghazarian D. Skin adnexal neoplasms--part 2: an approach to tumours of cutaneous sweat glands. J Clin Pathol. 2007;60:145-59 pubmed
    ..Composite/mixed adnexal tumours are also discussed briefly...
  34. Kuo H, Ohara K. Pigmented eccrine poroma: a report of two cases and study with dermatoscopy. Dermatol Surg. 2003;29:1076-9 pubmed
    ..However, detailed information about the pigmented variant of eccrine poroma is not available...
  35. Krishnakumar S, Mohan E, Babu K, Das D, Biswas J. Eccrine duct carcinoma of the eyelid mimicking meibomian carcinoma: clinicopathological study of a case. Surv Ophthalmol. 2003;48:439-46 pubmed
    ..The differential diagnosis of eccrine carcinomas based on light microscopy, enzyme histochemistry, and immunohistochemistry is discussed, and a list of the various malignant eccrine tumors reported in the lid is presented...
  36. Tsubura A, Senzaki H, Sasaki M, Hilgers J, Morii S. Immunohistochemical demonstration of breast-derived and/or carcinoma-associated glycoproteins in normal skin appendages and their tumors. J Cutan Pathol. 1992;19:73-9 pubmed
    ..These MoAbs appear to be valuable markers for the study of normal skin appendages and their tumors...
  37. Kramer T, Grossniklaus H, McLean I, Orcutt J, Green W, Iliff N, et al. Histiocytoid variant of eccrine sweat gland carcinoma of the eyelid and orbit: report of five cases. Ophthalmology. 2002;109:553-9 pubmed
    ..To study the clinicopathologic features of the histiocytoid variant of adenocarcinoma of the eccrine sweat gland of the eye and orbit...
  38. Timpanidis P, Lakhani S, Groves R. Progesterone receptor-positive eruptive syringoma associated with diabetes. J Am Acad Dermatol. 2003;48:S103-4 pubmed
    ..We report a case in which eruptive syringoma with clear cell morphology was found to express progesterone receptors, suggesting the possibility of hormonal control of the tumor...
  39. Leonard N, Smith D, McNamara P. Low-grade malignant eccrine spiradenoma with systemic metastases. Am J Dermatopathol. 2003;25:253-5 pubmed
    ..It had a monotonous appearance with few mitotic figures and minimal pleomorphism. Vascular invasion was seen in both cases of low-grade MES and may be an important prognostic feature...
  40. Chi C, Tsai R, Wang S. Syringocystadenocarcinoma papilliferum: successfully treated with Mohs micrographic surgery. Dermatol Surg. 2004;30:468-71 pubmed
    ..Syringocystadenocarcinoma papilliferum, a rare sweat gland carcinoma, is the malignant counterpart of syringocystadenoma papilliferum...
  41. Swinson B, Ryan F, Barrett A, Jerjes W, Landon G, Calonje E, et al. Histiocytoid eccrine sweat gland carcinoma of the eyelid: report of a case. Clin Exp Dermatol. 2006;31:786-9 pubmed
    ..However, a metastatic lesion was excluded by clinical and imaging investigations. There has been no recurrence 3 years after primary excision...
  42. Ribeiro Silva A, Shaletich C, Careta R, Kazava D, Siqueira M, Ponton F. Spiradenocarcinoma of the breast arising in a long-standing spiradenoma. Ann Diagn Pathol. 2004;8:162-6 pubmed
    ..Some histogenetic concepts relevant to this case are discussed, along with a brief review of this neoplasm...
  43. Huang Y, Chuang Y, Kuo T, Yang L, Hong H. Vulvar syringoma: a clinicopathologic and immunohistologic study of 18 patients and results of treatment. J Am Acad Dermatol. 2003;48:735-9 pubmed
    ..Syringoma of the vulva has been rarely reported. No effective treatment modality has been documented...
  44. Arai Y, Kusakabe H, Kiyokane K. A case of syringocystadenocarcinoma papilliferum in situ occurring partially in syringocystadenoma papilliferum. J Dermatol. 2003;30:146-50 pubmed
  45. Ohnishi T, Watanabe S. Immunohistochemical analysis of cytokeratin expression in apocrine cystadenoma or hidrocystoma. J Cutan Pathol. 1999;26:295-300 pubmed
    ..e. the dermal duct, the junction of the excretory ductal portion with the secretory portion, and the secretory portion...
  46. de Viragh P, Szeimies R, Eckert F. Apocrine cystadenoma, apocrine hidrocystoma, and eccrine hidrocystoma: three distinct tumors defined by expression of keratins and human milk fat globulin 1. J Cutan Pathol. 1997;24:249-55 pubmed
    ..Also, hidrocystomas often prove to be histologically misdiagnosed apocrine cystadenomas because of a flattened cyst wall secondary to increased intraluminal pressure...
  47. Nishie W, Sawamura D, Mayuzumi M, Takahashi S, Shimizu H. Hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammary-like glands. J Cutan Pathol. 2004;31:561-4 pubmed
    ..In this study, it has been suggested that this tumor might have been developed from these mammary-like glands...
  48. Hsu P, Liu C, Huang C. Mixed tubulopapillary hidradenoma and syringocystadenoma papilliferum occurring as a verrucous tumor. J Cutan Pathol. 2003;30:206-10 pubmed
    ..Although PCR and DNA probe hybridization for human papilloma virus (HPV) types 2, 6/11, 16 and 18 failed to reveal positive results, the location and clinicopathologic correlation convinced us that superimposed HPV could not be excluded...
  49. González López M, Vázquez López F, Soler T, Gómez Díez S, Garcia Y, Manjon J, et al. Metastatic eccrine porocarcinoma: a 5.6-year follow-up study of a patient treated with a combined therapeutic protocol. Dermatol Surg. 2003;29:1227-32 pubmed
    ..Metastatic eccrine porocarcinoma (EP) is an uncommon, malignant, and potentially lethal neoplasm that arises from the eccrine sweat glands...
  50. Verret D, Kabbani W, DeFatta R. Nodular hidradenocarcinoma over the parotid gland: a pathologic presentation. Head Neck. 2007;29:193-7 pubmed
  51. Frazier C, Camacho A, Cockerell C. The treatment of eruptive syringomas in an African American patient with a combination of trichloroacetic acid and CO2 laser destruction. Dermatol Surg. 2001;27:489-92 pubmed
    ..Many treatment modalities such as dermabrasion, electrodesiccation with curettage, and scissors excision have been tried with some success, but more recently lasers have provided good to excellent results...
  52. Ko C, Cochran A, Eng W, Binder S. Hidradenocarcinoma: a histological and immunohistochemical study. J Cutan Pathol. 2006;33:726-30 pubmed
    ..In making the diagnosis of hidradenocarcinoma, it may be unnecessary to separate hidradenocarcinoma into eccrine and apocrine categories, and although Ki67 and p53 may be helpful, histological parameters remain paramount...
  53. Battistella M, Langbein L, Peltre B, Cribier B. From hidroacanthoma simplex to poroid hidradenoma: clinicopathologic and immunohistochemic study of poroid neoplasms and reappraisal of their histogenesis. Am J Dermatopathol. 2010;32:459-68 pubmed publisher
    ..The 3 latter are rarely reported. Poroid cells in P have recently been identified as keratinocytes of the lowermost acrosyringium and the sweat duct ridge...