odontogenic tumors

Summary

Summary: Neoplasms produced from tooth-forming tissues.

Top Publications

  1. Mosqueda Taylor A. New findings and controversies in odontogenic tumors. Med Oral Patol Oral Cir Bucal. 2008;13:E555-8 pubmed
    b>Odontogenic tumors comprise a heterogeneous group of lesions that ranges from hamartomas to benign and malignant neoplasms of variable aggressiveness...
  2. Mendes R, Carvalho J, van der Waal I. Characterization and management of the keratocystic odontogenic tumor in relation to its histopathological and biological features. Oral Oncol. 2010;46:219-25 pubmed publisher
    ..The key element for future management of KCOTs will probably be based on thorough knowledge of the biological basis of this tumor, thereby enabling a more tailored treatment approach...
  3. Ruhin Poncet B, Ghoul Mazgar S, Hotton D, Capron F, Jaafoura M, Goubin G, et al. Msx and dlx homeogene expression in epithelial odontogenic tumors. J Histochem Cytochem. 2009;57:69-78 pubmed publisher
    Epithelial odontogenic tumors are rare jaw pathologies that raise clinical diagnosis and prognosis dilemmas notably between ameloblastomas and clear cell odontogenic carcinomas (CCOCs)...
  4. Osterne R, Brito R, Alves A, Cavalcante R, Sousa F. Odontogenic tumors: a 5-year retrospective study in a Brazilian population and analysis of 3406 cases reported in the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;111:474-81 pubmed publisher
    The objective of this study was to analyze the frequency and distribution of odontogenic tumors in Fortaleza, Brazil, and compare the findings with those reported in the literature...
  5. Saghravanian N, Jafarzadeh H, Bashardoost N, Pahlavan N, Shirinbak I. Odontogenic tumors in an Iranian population: a 30-year evaluation. J Oral Sci. 2010;52:391-6 pubmed
    ..Although the prevalence of odontogenic tumors varies in different geographic sites, there are no reports in English on the relative frequency of ..
  6. Mendes R, Carvalho J, van der Waal I. Biological pathways involved in the aggressive behavior of the keratocystic odontogenic tumor and possible implications for molecular oriented treatment - an overview. Oral Oncol. 2010;46:19-24 pubmed publisher
    ..Genetic and molecular research regarding odontogenic tumors, and KCOTs in particular, has led to an increasing amount of knowledge and understanding of their ..
  7. Jurisic M, Andric M, Dos Santos J, Jurisic V. Clinical, diagnostic and therapeutic features of keratocystic odontogenic tumors: a review. J BUON. 2012;17:237-44 pubmed
    Keratocystic odontogenic tumors (KCOTs) are benign but locally aggressive lesions of the gnathic skeleton with high propensity to recur following surgical treatment...
  8. Albanese M, Nocini P, Fior A, Rizzato A, Cristofaro M, Sancassani G, et al. Mandibular reconstruction using fresh frozen bone allograft after conservative enucleation of a mandibular odontogenic myxoma. J Craniofac Surg. 2012;23:831-5 pubmed publisher
    ..The use of fresh-frozen bone allograft, thanks to its osteoinductive and osteoconductive properties, may represent an optional choice for reconstruction of bone defects after jaw tumor removal...
  9. Mosqueda Taylor A, Martínez Mata G, Carlos Bregni R, Vargas P, Toral Rizo V, Cano Valdez A, et al. Central odontogenic fibroma: new findings and report of a multicentric collaborative study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112:349-58 pubmed publisher
    ..The aim of this study was to describe the clinicopathologic and immunohistochemical characteristics of 14 cases of central odontogenic fibroma (COF), and the ultrastructural features of 2 of them...

More Information

Publications66

  1. Varkhede A, Tupkari J, Sardar M. Odontogenic tumors: a study of 120 cases in an Indian teaching hospital. Med Oral Patol Oral Cir Bucal. 2011;16:e895-9 pubmed
    Studies on odontogenic tumors published from many parts of the world show a distinct geographic variation; however, there is little information available in the English-language literature on the relative frequency of odontogenic tumors ..
  2. Ide F, Mishima K, Saito I, Kusama K. Diagnostically challenging epithelial odontogenic tumors: a selective review of 7 jawbone lesions. Head Neck Pathol. 2009;3:18-26 pubmed publisher
    Considerable variation in the clinicopathologic presentation of epithelial odontogenic tumors can sometimes be confusing and increase the chance of misdiagnosis. Seven diagnostically challenging jawbone lesions are described...
  3. Guler N, Sencift K, Demirkol O. Conservative management of keratocystic odontogenic tumors of jaws. ScientificWorldJournal. 2012;2012:680397 pubmed publisher
    The aim of this study was to evaluate different surgical treatment methods for keratocystic odontogenic tumors (KCOTs) and the outcome of those treatments over a 9-year period.
  4. Tawfik M, Zyada M. Odontogenic tumors in Dakahlia, Egypt: analysis of 82 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109:e67-73 pubmed publisher
    This study was designed to analyze the frequency and distribution of different types of odontogenic tumors in Dakahlia, Egypt, and to compare them with various reports from other parts of the world.
  5. Shimada Y, Morita K, Kabasawa Y, Taguchi T, Omura K. Clinical manifestations and treatment for keratocystic odontogenic tumors associated with nevoid basal cell carcinoma syndrome: a study in 25 Japanese patients. J Oral Pathol Med. 2013;42:275-80 pubmed publisher
    ..Keratocystic odontogenic tumors (KCOTs) of the jaws are a common manifestation of this syndrome...
  6. Sun L, Li X, Li T. PTCH1 and SMO gene alterations in keratocystic odontogenic tumors. J Dent Res. 2008;87:575-9 pubmed
    Keratocystic odontogenic tumors (KCOTs, previously known as odontogenic keratocysts) are aggressive jaw lesions that may occur in isolation or in association with nevoid basal cell carcinoma syndrome (NBCCS)...
  7. Mateus G, Lanza G, de Moura P, Marigo H, Horta M. Cell proliferation and apoptosis in keratocystic odontogenic tumors. Med Oral Patol Oral Cir Bucal. 2008;13:E697-702 pubmed
    Keratocystic odontogenic tumors (KOTs), also known as odontogenic keratocysts, were recently classified as a benign neoplasia due to the aggressive clinical behavior...
  8. Murphy C, Kestler D, Foster J, Wang S, Macy S, Kennel S, et al. Odontogenic ameloblast-associated protein nature of the amyloid found in calcifying epithelial odontogenic tumors and unerupted tooth follicles. Amyloid. 2008;15:89-95 pubmed publisher
    We have previously reported that the amyloid found in three patients with calcifying epithelial odontogenic tumors (CEOT) was composed of N-terminal fragments of a putative 153-residue protein specified by a gene designated FLJ20513 now ..
  9. Sriram G, Shetty R. Odontogenic tumors: a study of 250 cases in an Indian teaching hospital. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105:e14-21 pubmed publisher
    Studies on odontogenic tumors published from many parts of the world show a distinct geographic variation...
  10. Leiser Y, Abu El Naaj I, Peled M. Odontogenic myxoma--a case series and review of the surgical management. J Craniomaxillofac Surg. 2009;37:206-9 pubmed publisher
    ..Since these neoplasms are rare in the oral cavity, the possible surgical management can be quite variable. Literature recommendation can vary from simple curettage and peripheral ostectomy up to segmental resection...
  11. Sasaki R, Miyashita T, Matsumoto N, Fujii K, Saito K, Ando T. Multiple keratocystic odontogenic tumors associated with nevoid basal cell carcinoma syndrome having distinct PTCH1 mutations: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110:e41-6 pubmed publisher
    ..Although multiple jaw tumors, such as keratocystic odontogenic tumors (KCOTs), are one of the most frequent complications in NBCCS, the molecular mechanism for how KCOTs develop ..
  12. Pan S, Dong Q, Sun L, Li T. Mechanisms of inactivation of PTCH1 gene in nevoid basal cell carcinoma syndrome: modification of the two-hit hypothesis. Clin Cancer Res. 2010;16:442-50 pubmed publisher
    ..Keratocystic odontogenic tumors (KCOT) are aggressive jaw lesions that may occur in isolation or in association with NBCCS...
  13. Alaeddini M, Salehizadeh S, Baghaii F, Etemad Moghadam S. A retrospective analysis of peripheral odontogenic fibroma in an Iranian population. J Oral Maxillofac Surg. 2010;68:2099-103 pubmed publisher
    ..The aim of this study was to assess the relative frequency of peripheral odontogenic fibroma (POdF) in an Iranian population and to compare the obtained data with previous reports...
  14. de Oliveira M, Lauxen I, Chaves A, Rados P, Sant Ana Filho M. Odontogenic epithelium: immunolabeling of Ki-67, EGFR and survivin in pericoronal follicles, dentigerous cysts and keratocystic odontogenic tumors. Head Neck Pathol. 2011;5:1-7 pubmed publisher
    ..epithelium by immunolabeling of epidermal growth factor receptor (EGFR), Ki-67 and survivin in keratocystic odontogenic tumors (KOT), dentigerous cysts (DC), and pericoronal follicles (PF)...
  15. Gomes C, Diniz M, Duarte A, Bernardes V, Gomez R. Molecular review of odontogenic myxoma. Oral Oncol. 2011;47:325-8 pubmed publisher
  16. Alaeddini M, Salah S, Dehghan F, Eshghyar N, Etemad Moghadam S. Comparison of angiogenesis in keratocystic odontogenic tumours, dentigerous cysts and ameloblastomas. Oral Dis. 2009;15:422-7 pubmed publisher
    ..The aim of the present study was to evaluate and compare angiogenesis in keratocystic odontogenic tumours, dentigerous cysts (DCs) and ameloblasomas using monoclonal antibody against CD34...
  17. Friedrich R, Scheuer H, Zustin J. Adenomatoid odontogenic tumor (AOT) of maxillary sinus: case report with respect to immunohistochemical findings. In Vivo. 2009;23:111-6 pubmed
    ..The tumor showed immunoreactivity for certain types of cytokeratins, vimentin and p63, and was focally immunoreactive for alpha smooth muscle actin and epithelial membrane antigen...
  18. de Macedo L, de Macedo N, do Socorro Ferreira Monteiro A. Fresh-frozen human bone graft for repair of defect after adenomatoid odontogenic tumour removal. Cell Tissue Bank. 2009;10:221-6 pubmed publisher
    ..Treatment was conservative and the prognosis was excellent. The patient has been followed-up for without recurrence. The use of fresh-frozen human bone graft can be a safe choice for reconstruction of the bone defects to treat AOT...
  19. Mendes R, Carvalho J, van der Waal I. A comparative immunohistochemical analysis of COX-2, p53, and Ki-67 expression in keratocystic odontogenic tumors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;111:333-9 pubmed publisher
    The aim of the present study was to investigate the association between the expression of cyclooxygenase-2 (COX-2) in keratocystic odontogenic tumors (KCOT) and more commonly used markers, such as p53 and Ki-67.
  20. Tsuneki M, Yamazaki M, Cheng J, Maruyama S, Kobayashi T, Saku T. Combined immunohistochemistry for the differential diagnosis of cystic jaw lesions: its practical use in surgical pathology. Histopathology. 2010;57:806-13 pubmed publisher
    ..The aim of this study was to seek practical measures to differentiate such lesions...
  21. Apajalahti S, Hagstrom J, Lindqvist C, Suomalainen A. Computerized tomography findings and recurrence of keratocystic odontogenic tumor of the mandible and maxillofacial region in a series of 46 patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;111:e29-37 pubmed publisher
    The aim of this study was to evaluate the computerized tomography (CT) features of keratocystic odontogenic tumors (KCOTs). Another aim was to determine the recurrence rate of KCOTs during a mean follow-up of 4.7 years.
  22. da Costa D, Maurício A, de Faria P, da Silva L, Mosqueda Taylor A, Lourenço S. Odontogenic tumors: a retrospective study of four Brazilian diagnostic pathology centers. Med Oral Patol Oral Cir Bucal. 2012;17:e389-94 pubmed
    This article presents the results of a retrospective study of the frequency and classification of odontogenic tumors recorded at four centers of diagnostic pathology in Rio de Janeiro, Brazil.
  23. Friedrich R, Zustin J. Calcifying epithelial odontogenic tumour of the maxilla: a case report with respect to immunohistochemical findings. In Vivo. 2011;25:259-64 pubmed
  24. Seifi S, Shafaie S, Ghadiri S. Microvessel density in follicular cysts, keratocystic odontogenic tumours and ameloblastomas. Asian Pac J Cancer Prev. 2011;12:351-6 pubmed
  25. Gurgel C, Ramos E, Azevedo R, Sarmento V, da Silva Carvalho A, dos Santos J. Expression of Ki-67, p53 and p63 proteins in keratocyst odontogenic tumours: an immunohistochemical study. J Mol Histol. 2008;39:311-6 pubmed publisher
    ..To investigate the immunohistochemical expression of Ki-67, p53 and p63 in Keratocyst Odontogenic Tumours (KOTs) in order to contribute to the biological profile of this tumor...
  26. Avelar R, Antunes A, Santos T, Andrade E, Dourado E. Odontogenic tumors: clinical and pathology study of 238 cases. Braz J Otorhinolaryngol. 2008;74:668-73 pubmed
    b>Odontogenic tumors are neoplasms that develops exclusively in the gnathic bones; they originate from odontogenic tissues, by epithelial or mesenchymal proliferation, or both.
  27. Brar R, Kulkarni S, Sheikh S, Jindal S, Brar P. Hemangiopericytoma associated with multiple keratocystic odontogenic tumors in an adolescent patient: a case report. J Oral Sci. 2008;50:233-7 pubmed
    ..Here we present a case of hemangiopericytoma of the submandibular region with keratocystic odontogenic tumors in an adolescent patient.
  28. El Gehani R, Orafi M, Elarbi M, Subhashraj K. Benign tumours of orofacial region at Benghazi, Libya: a study of 405 cases. J Craniomaxillofac Surg. 2009;37:370-5 pubmed publisher
    ..The purpose of this study was to systematically analyse the incidence of benign tumours of maxillofacial region within the Libyan population...
  29. Cakur B, Miloglu O, Yolcu U, Goregen M, Gursan N. Keratocystic odontogenic tumor invading the right maxillary sinus: a case report. J Oral Sci. 2008;50:345-9 pubmed
    ..We present the case of a 23-year-old man with extensive KCOT and impacted third molar in the right maxillary sinus. The clinical, radiological, and histological features of this tumor and its surgical management are discussed...
  30. González Alva P, Tanaka A, Oku Y, Yoshizawa D, Itoh S, Sakashita H, et al. Keratocystic odontogenic tumor: a retrospective study of 183 cases. J Oral Sci. 2008;50:205-12 pubmed
    ..Pathological examination of KCOT is important to avoid misdiagnosis and provide appropriate treatment and follow-up...
  31. Rawal Y, Mustiful Martin D, Rosebush M, Anderson K, Mincer H. Slow-growing gingival mass. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113:161-7 pubmed publisher
    ..diagnosis included benign tumors and tumor-like lesions, including the pyogenic granuloma, peripheral giant cell granuloma, peripheral ossifying fibroma, giant cell fibroma, peripheral odontogenic tumors, and oral focal mucinosis.
  32. Luo H, Li T. Odontogenic tumors: a study of 1309 cases in a Chinese population. Oral Oncol. 2009;45:706-11 pubmed publisher
    To determine the relative frequency of odontogenic tumors (OTs) in a Chinese population, files from the department of oral pathology, Peking University School and Hospital of Stomatology, were systematically reviewed for all OTs during ..
  33. Li T. The odontogenic keratocyst: a cyst, or a cystic neoplasm?. J Dent Res. 2011;90:133-42 pubmed publisher
    ..Since some advocate a more conservative treatment for OKCs, notably marsupialization and decompression, future treatment strategies may focus on molecular approaches and eventually reduce or eliminate the need for aggressive surgeries...
  34. Madras J, Lapointe H. Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour. J Can Dent Assoc. 2008;74:165-165h pubmed
    ..Future treatment may involve molecular-based modalities, which may reduce or eliminate the need for aggressive surgical management...
  35. Hyun H, Hong S, Kim J. Recurrent keratocystic odontogenic tumor in the mandible: a case report and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108:e7-10 pubmed publisher
    ..Here we report a case of a 7-year-old patient with a recurrent keratocystic odontogenic tumor treated by marsupialization for normal development of the involved teeth...
  36. Diniz M, Gomes C, de Castro W, Guimarães A, de Paula A, Amm H, et al. miR-15a/16-1 influences BCL2 expression in keratocystic odontogenic tumors. Cell Oncol (Dordr). 2012;35:285-91 pubmed publisher
    ..Additionally, we demonstrated that miRNA expression increases after marsupialization, implicating an etiological and therapeutic role of miRNAs in KCOT. ..
  37. Raitz R, Assunção Júnior J, Correa L, Fenyo Pereira M. Parameters in panoramic radiography for differentiation of radiolucent lesions. J Appl Oral Sci. 2009;17:381-7 pubmed
    ..The aims of this study were to establish parameters in panoramic radiography for interpretation of unilocular radiolucent lesions, and to compare the accuracy of diagnoses given by examiners before and after using these parameters...
  38. Gratzinger D, Salama M, Poh C, Rouse R. Ameloblastoma, calcifying epithelial odontogenic tumor, and glandular odontogenic cyst show a distinctive immunophenotype with some myoepithelial antigen expression. J Oral Pathol Med. 2008;37:177-84 pubmed publisher
    ..In the 1980s, an ultrastructural study identified a population of myoepithelial-like cells in calcifying epithelial odontogenic tumor. Myoepithelial derived tumors have since been shown to have distinct immunohistochemical profiles...
  39. Ide F, Mishima K, Saito I, Kusama K. Rare peripheral odontogenic tumors: report of 5 cases and comprehensive review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106:e22-8 pubmed publisher
    ..At this time, it remains to be determined whether the biologic behavior of PKCOT is the same as for KCOT. In view of the reported cases, a true extraosseous origin of PAOT and PAF, for the most part, is challenging...
  40. Gupta B, Ponniah I. The pattern of odontogenic tumors in a government teaching hospital in the southern Indian state of Tamil Nadu. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110:e32-9 pubmed publisher
    This hospital-based study was designed to provide demographic data on odontogenic tumors from the southern Indian population in the state of Tamil Nadu for comparison with pertinent series from other geographic regions.
  41. Hakim S, Kosmehl H, Sieg P, Trenkle T, Jacobsen H, Attila Benedek G, et al. Altered expression of cell-cell adhesion molecules ?-catenin/E-cadherin and related Wnt-signaling pathway in sporadic and syndromal keratocystic odontogenic tumors. Clin Oral Investig. 2011;15:321-8 pubmed publisher
  42. Guo Y, Zhang J, Li X, Luo H, Chen F, Li T. PTCH1 gene mutations in Keratocystic odontogenic tumors: a study of 43 Chinese patients and a systematic review. PLoS ONE. 2013;8:e77305 pubmed publisher
    ..PTCH1, the gene responsible for NBCCS, may play an important role in sporadic KCOTs. In this study, we analyzed and compared the distribution pattern of PTCH1 mutations in patients with sporadic and NBCCS-associated KCOTs...
  43. Poomsawat S, Punyasingh J, Vejchapipat P, Larbcharoensub N. Co-expression of hepatocyte growth factor and c-met in epithelial odontogenic tumors. Acta Histochem. 2012;114:400-5 pubmed publisher
    ..has been demonstrated in various tumors, however, little is known about the role of HGF/c-met pathway in odontogenic tumors. The aim of this study was to characterize the expression of HGF and c-met in 30 ameloblastomas, 7 unicystic ..
  44. Boffano P, Gallesio C, Barreca A, Bianchi F, Garzino Demo P, Roccia F. Surgical treatment of odontogenic myxoma. J Craniofac Surg. 2011;22:982-7 pubmed publisher
    ..There is no consensus about the surgical treatment of odontogenic myxoma. The aim of the current study was to present our experience and discuss the surgical management and outcome in 10 patients diagnosed with odontogenic myxoma...
  45. Zecha J, Mendes R, Lindeboom V, van der Waal I. Recurrence rate of keratocystic odontogenic tumor after conservative surgical treatment without adjunctive therapies - A 35-year single institution experience. Oral Oncol. 2010;46:740-2 pubmed publisher
  46. Grasmuck E, Nelson B. Keratocystic odontogenic tumor. Head Neck Pathol. 2010;4:94-6 pubmed publisher
    ..These characteristics are reviewed in the setting of a typical presentation. The newly acknowledged neoplastic potential and its implications for treatment strategies are also discussed...
  47. Mesquita A, Santos C, Gomez R, Jorge J, Leon J, de Almeida O. Central granular cell odontogenic tumor: a histopathologic and immunohistochemical study. Ann Diagn Pathol. 2009;13:405-12 pubmed publisher
    ..Ki-67 labeling index was 1.8%, whereas p53 was negative. These data confirm the benign nature of CGCOT, the association of OE with Langerhans cells, and a variable phenotype of the granular cells...
  48. Gaitán Cepeda L, Quezada Rivera D, Tenorio Rocha F, Leyva Huerta E. Reclassification of odontogenic keratocyst as tumour. Impact on the odontogenic tumours prevalence. Oral Dis. 2010;16:185-7 pubmed publisher
    ..The aim of this study was to establish the impact of the redefinition and reclassification of odontogenic keratocyst (OKC) as a tumour on the prevalence of odontogenic tumours (OT)...
  49. Gao Y, Yang G, Weng T, Du J, Wang X, Zhou J, et al. Disruption of Smad4 in odontoblasts causes multiple keratocystic odontogenic tumors and tooth malformation in mice. Mol Cell Biol. 2009;29:5941-51 pubmed publisher
    Keratocystic odontogenic tumors (KCOTs) are cystic epithelial neoplasias with a high recurrence rate. However, the molecular mechanisms underlying the initiation and progression of KCOTs are still largely unknown...
  50. de Medeiros A, Nonaka C, Galvão H, de Souza L, Freitas R. Expression of extracellular matrix proteins in ameloblastomas and adenomatoid odontogenic tumors. Eur Arch Otorhinolaryngol. 2010;267:303-10 pubmed publisher
    ..evaluated the expression of fibronectin, tenascin and type I collagen in ameloblastomas and adenomatoid odontogenic tumors (AOTs) aiming to contribute with the comprehension of the differences in the biological behavior of these ..
  51. Crusoé Rebello I, Oliveira C, Campos P, Azevedo R, dos Santos J. Assessment of computerized tomography density patterns of ameloblastomas and keratocystic odontogenic tumors. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108:604-8 pubmed publisher
    ..patterns of solid ameloblastomas (SA), unicystic ameloblastomas (UA), and sporadic and multiple keratocystic odontogenic tumors (SK and MK, respectively)...
  52. Koutlas I, Allen C, Warnock G, Manivel J. Sclerosing odontogenic carcinoma: a previously unreported variant of a locally aggressive odontogenic neoplasm without apparent metastatic potential. Am J Surg Pathol. 2008;32:1613-9 pubmed publisher
    ..We propose the name sclerosing odontogenic carcinoma. As current classifications of odontogenic tumors do not include such examples, it is important that pathologists become aware of this entity...
  53. Boffano P, Ruga E, Gallesio C. Keratocystic odontogenic tumor (odontogenic keratocyst): preliminary retrospective review of epidemiologic, clinical, and radiologic features of 261 lesions from University of Turin. J Oral Maxillofac Surg. 2010;68:2994-9 pubmed publisher
    To analyze and discuss the demographic, clinical, and surgical aspects of 261 surgically treated keratocystic odontogenic tumors.
  54. Gadbail A, Hande A, Chaudhary M, Nikam A, Gawande M, Patil S, et al. Tumor angiogenesis in keratocystic odontogenic tumor assessed by using CD-105 antigen. J Oral Pathol Med. 2011;40:263-9 pubmed publisher
    The purpose of this study was to assess and compare angiogenesis with proliferative activity in Keratocystic odontogenic tumors (KCOT) and dentigerous cysts (DC) by using monoclonal mouse anti-human antibody against CD105 (endoglin).
  55. Crivelini M, Felipini R, Miyahara G, de Sousa S. Expression of odontogenic ameloblast-associated protein, amelotin, ameloblastin, and amelogenin in odontogenic tumors: immunohistochemical analysis and pathogenetic considerations. J Oral Pathol Med. 2012;41:272-80 pubmed publisher
    ..for expression of amelogenesis-related proteins represents a powerful molecular approach to characterize odontogenic tumors and investigate their pathogenesis...
  56. Avelar R, Primo B, Pinheiro Nogueira C, Studart Soares E, de Oliveira R, Romulo de Medeiros J, et al. Worldwide incidence of odontogenic tumors. J Craniofac Surg. 2011;22:2118-23 pubmed publisher
    The objective of the study was to determine the relative frequency of odontogenic tumors (OTs) in the world population, directing an epidemiologic profile to these lesions.
  57. Pastorino L, Pollio A, Pellacani G, Guarneri C, Ghiorzo P, Longo C, et al. Novel PTCH1 mutations in patients with keratocystic odontogenic tumors screened for nevoid basal cell carcinoma (NBCC) syndrome. PLoS ONE. 2012;7:e43827 pubmed publisher
    Keratocystic odontogenic tumors (KCOTs) are cystic tumors that arise sporadically or associated with nevoid basal cell carcinoma syndrome (NBCCS)...