mongolian spot

Summary

Summary: A bluish-gray to gray-brown benign, melanocytic nevus found usually in the LUMBOSACRAL REGION of dark-skinned people, especially those of East Asian ancestry. It is usually congenital or appears shortly after birth, and disappears in childhood.

Top Publications

  1. Gupta D, Thappa D. Mongolian spots--a prospective study. Pediatr Dermatol. 2013;30:683-8 pubmed publisher
    ..Seven hundred ninety babies (51.8%) had a single MS. More than 40% of MS disappeared by 1 year. Multiple patches, extrasacral position, size larger than 10 cm, and dark-colored lesions were markers of persistence beyond 1 year. ..
  2. Chang B, Hsu C, Chen H, Hsieh J. An infant with extensive Mongolian spot, naevus flammeus and cutis marmorata telangiectatica congenita: a unique case of phakomatosis pigmentovascularis. Br J Dermatol. 2007;156:1068-71 pubmed
  3. Gupta D, Thappa D. Mongolian spots. Indian J Dermatol Venereol Leprol. 2013;79:469-78 pubmed publisher
    ..Mongolian spots usually resolve by early childhood and hence no treatment is generally needed if they are located in the sacral area. However, sometimes it may be required for extrasacral lesions for cosmesis...
  4. Egemen A, Ikizoğlu T, Ergör S, Mete Asar G, Yilmaz O. Frequency and characteristics of mongolian spots among Turkish children in Aegean region. Turk J Pediatr. 2006;48:232-6 pubmed
    ..In conclusion, identifying mongolian spots and informing parents are essential to strengthen the family-doctor relationship...
  5. Leung A, Kao C, Leung A. Persistent Mongolian spots in Chinese adults. Int J Dermatol. 2005;44:43-5 pubmed
    ..Two patients had the spots on their arms while the other two had the spots on their shoulders. The persistence of Mongolian spots in Chinese adults has not been previously reported...
  6. Chatproedprai S, Wananukul S. Survey of common cutaneous lesions in healthy infants at the well baby clinic. J Med Assoc Thai. 2008;91:1356-9 pubmed
    ..Survey the prevalence of cutaneous disorders in infants at the well baby clinic...
  7. Willemsen M, Rotteveel J. Mongolian spots in Sjögren-Larsson syndrome. Pediatr Dermatol. 2008;25:285 pubmed publisher
  8. Shirakawa M, Ozawa T, Ohasi N, Ishii M, Harada T. Comparison of regional efficacy and complications in the treatment of aberrant Mongolian spots with the Q-switched ruby laser. J Cosmet Laser Ther. 2010;12:138-42 pubmed publisher
    ..However, so far as we could determine, there is no statistical analysis of the treatment of AMS. This paper shows statistical comparisons of the efficacy and complications in the treatment of AMS with QSRL...
  9. Larralde M, Santos Muñoz A, Rodríguez Cáceres M, Ciardiullo A. Phacomatosis pigmentovascularis type Va in a 3-month old. Pediatr Dermatol. 2008;25:198-200 pubmed publisher
    ..We report a 3-month-old girl with diagnosis of phacomatosis pigmentovascularis type V...

More Information

Publications38

  1. Hall B, Cadle R, Morrill Cornelius S, Bay C. Phakomatosis pigmentovascularis: Implications for severity with special reference to Mongolian spots associated with Sturge-Weber and Klippel-Trenaunay syndromes. Am J Med Genet A. 2007;143A:3047-53 pubmed
    ..This may be particularly true either of children of Asian, Hispanic or African heritage or any individuals from darker pigmented skin groups...
  2. Shih I, Lin J, Chen C, Hong H. A birthmark survey in 500 newborns: clinical observation in two northern Taiwan medical center nurseries. Chang Gung Med J. 2007;30:220-5 pubmed
    ..How gender and maturity of newborns affect presentation and prevalence of vascular birthmarks, in particular, has not been well documented. The aim of this survey was to catalog the above-mentioned problems...
  3. Castori M, Sarazani S, Binni F, Pezzella F, Cruciani G, Grammatico P. Monozygotic twin discordance for phacomatosis cesioflammea further supports the post-zygotic mutation hypothesis. Am J Med Genet A. 2011;155A:2253-6 pubmed publisher
    ..twins were observed shortly after birth, one affected by PPV and the other healthy, except for a standard Mongolian spot. Membrane examination was compatible with a monochorionic diamniotic pregnancy, and microsatellite analysis ..
  4. Taieb A, Boralevi F. Hypermelanoses of the newborn and of the infant. Dermatol Clin. 2007;25:327-36, viii pubmed
    ..Recently, molecular diagnosis has become available for some rare entities, such as hereditary symmetrical dyschromatoses, but the bulk of nevoid lesions are not understood at the molecular level...
  5. Inamadar A, Palit A. Persistent, aberrant Mongolian spots in Sjögren-Larsson syndrome. Pediatr Dermatol. 2007;24:98-9 pubmed
  6. Toriyama K, Morishita T, Kamei Y, Torii S. Accentuated varicella eruption: a complication of Q-switched alexandrite laser treatment. Plast Reconstr Surg. 2006;117:2108-9 pubmed
  7. Torrelo A, Zambrano A, Happle R. Large aberrant Mongolian spots coexisting with cutis marmorata telangiectatica congenita (phacomatosis pigmentovascularis type V or phacomatosis cesiomarmorata). J Eur Acad Dermatol Venereol. 2006;20:308-10 pubmed
    ..More recently, the term phacomatosis cesiomarmorata (cesius = blue) has been proposed. We believe phacomatosis cesiomarmorata is another example of twin spotting or didymosis...
  8. Kagami S, Asahina A, Uwajima Y, Miyamoto A, Yamada D, Shibata S, et al. Treatment of persistent Mongolian spots with Q-switched alexandrite laser. Lasers Med Sci. 2012;27:1229-32 pubmed publisher
  9. Lei H, Ye J, Qiu W, Zhang H, Han L, Wang Y, et al. Beta-galactosidase deficiencies and novel GLB1 mutations in three Chinese patients with Morquio B disease or GM1 gangliosidosis. World J Pediatr. 2012;8:359-62 pubmed publisher
    ..This paper aims to report GLB1 activities and mutation analysis of three patients from the mainland of China, one with Morquio B disease and two with GM1 gangliosidosis...
  10. Monteagudo B, Labandeira J, León Muiños E, Carballeira I, Corrales A, Cabanillas M, et al. [Prevalence of birthmarks and transient skin lesions in 1,000 Spanish newborns]. Actas Dermosifiliogr. 2011;102:264-9 pubmed publisher
    ..The aims of this study were to determine their prevalence in 1000 newborn children in the health care area of Ferrol in northwest Spain and to compare the results with those of 9 other studies with similar characteristics...
  11. Shirakawa M, Ozawa T, Tateishi C, Fujii N, Sakahara D, Ishii M. Intense pulsed light therapy for aberrant Mongolian spots. Osaka City Med J. 2012;58:59-65 pubmed
    ..As far as we could determine, there have been no clinical and histological studies on the treatment of AMS with IPL. Accordingly, the aim of this study was to assess the clinical and histological efficacy of IPL for AMS...
  12. Kagami S, Asahina A, Watanabe R, Mimura Y, Shirai A, Hattori N, et al. Laser treatment of 26 Japanese patients with Mongolian spots. Dermatol Surg. 2008;34:1689-94 pubmed publisher
    ..They are found most frequently in the sacral region and typically disappear during childhood. Occasionally, they persist to adulthood...
  13. Segatto M, Schmitt E, Hagemann L, Silva R, Cattani C. Phacomatosis pigmentovascularis type IIa--case report. An Bras Dermatol. 2013;88:85-8 pubmed publisher
    ..A case of a 2-year-old patient is reported, who presented extensive nevus flammeus and an aberrant Mongolian spot, without systemic disease, manifestations that allow us to classify this case as type IIa Phacomatosis ..
  14. Leung A, Robson W. Superimposed Mongolian spots. Pediatr Dermatol. 2008;25:233-5 pubmed publisher
    We report four Chinese infants with a darker pigmented Mongolian spot superimposed on another Mongolian spot. The presence of a superimposed Mongolian spot has not been previously reported...
  15. Castori M, Rinaldi R, Angelo C, Zambruno G, Grammatico P, Happle R. Phacomatosis cesioflammea with unilateral lipohypoplasia. Am J Med Genet A. 2008;146A:492-5 pubmed publisher
    Phacomatosis cesioflammea is characterized by the co-existence of a large nevus cesius (i.e., aberrant Mongolian spot, or nevus fuscocoeruleus) and an extensive nevus flammeus (i.e., port-wine stain)...
  16. Hann S, Im S, Chung W, Kim D. Pigmentary disorders in the South East. Dermatol Clin. 2007;25:431-8, x pubmed
    ..They are especially resistant to various kinds of conventional treatments and tend to have a chronic progression that makes patients doubt the results and the prognosis...
  17. Tanyasiri K, Kono T, Groff W, Higashimori T, Petrovska I, Sakurai H, et al. Mongolian spots with involvement of mandibular area. J Dermatol. 2007;34:381-4 pubmed
    ..This case report demonstrates that Mongolian spots can occur on the face in the area supplied by the mandibular branch of the trigeminal nerve. These spots should not be misdiagnosed as nevus of Ota...
  18. Moosavi Z, Hosseini T. One-year survey of cutaneous lesions in 1000 consecutive Iranian newborns. Pediatr Dermatol. 2006;23:61-3 pubmed
    ..3%), and miliaria (1.3%). The most frequent skin disorders were Mongolian spots, Epstein pearls, and sebaceous hyperplasia. Differences between our study findings and those of others may be based on racial differences and study method...
  19. Smith M, Schofield O. An infant presenting with skin colour changes. Clin Exp Dermatol. 2005;30:313-5 pubmed
  20. AlJasser M, Al Khenaizan S. Cutaneous mimickers of child abuse: a primer for pediatricians. Eur J Pediatr. 2008;167:1221-30 pubmed publisher
    ..Here, we review the most common cutaneous mimickers of child abuse in order to increase awareness of these disorders and reduce erroneous diagnosis of child abuse...
  21. Acebo E, Gardeazabal J, Gonzalez Hermosa R, Pérez Barrio S, Diaz Perez J. Congenital hemangioma: a report of evolution from rapidly involuting to noninvoluting congenital hemangioma with aberrant Mongolian spots. Pediatr Dermatol. 2009;26:225-6 pubmed publisher
    ..He also had aberrant, persistent Mongolian spots on both legs. To our knowledge, this association has not been reported to date...
  22. Wolf R, Wolf D, Davidovici B. Phacomatosis pigmentopigmentalis: aberrant Mongolian spots and segmental café au lait macules. Pediatr Dermatol. 2009;26:228-9 pubmed publisher
    ..lait spots on his left buttocks and left thigh down to the medial knee, in a nevoid pattern, and an aberrant Mongolian spot on the ipsilateral cheek of the buttocks in a checkerboard pattern...
  23. Moutray T, Napier M, Shafiq A, Fryer A, Rankin S, Willoughby C. Monozygotic twins discordant for phacomatosis pigmentovascularis: evidence for the concept of twin spotting. Am J Med Genet A. 2010;152A:718-20 pubmed publisher
    ..the right arm and the right maxilla, and a pigmented area on the trunk in keeping with a persistent, aberrant Mongolian spot. The affected twin had bilateral ocular melanocytosis with abnormal scleral pigmentation, iris mamillations, ..
  24. Reza A, Farahnaz G, Hamideh S, Alinaghi S, Saeed Z, Mostafa H. Incidence of Mongolian spots and its common sites at two university hospitals in Tehran, Iran. Pediatr Dermatol. 2010;27:397-8 pubmed publisher
    ..Mongolian spots were found in 11.4% and 37.3% of newborns at Shariati and Lolagar hospitals, respectively. The most frequent site of involvement is the sacral, followed by the gluteal area...
  25. Bilgili S, Akdeniz N, Karadag A, Akbayram S, Calka O, Ozkol H. Mucocutaneous disorders in children with down syndrome: case-controlled study. Genet Couns. 2011;22:385-92 pubmed
    ..Down's syndrome is the most frequent chromosomal anomaly that can affect a multiple organ systems, including skin. In this study, we compared the frequency of mucocutaneous disorders in children with Down's syndrome with normal children...
  26. Kose O, Huseynov S, Demiriz M. Giant Mongolian macules with bilateral ocular involvement: case report and review. Dermatology. 2012;224:126-9 pubmed publisher
    ..Her physical and mental development was normal. This association of blue macules and involvement of both sclerae does not represent a distinct entity and cannot be categorized as an example of nevus of Ota...
  27. Kagami S, Asahina A, Watanabe R, Mimura Y, Shirai A, Hattori N, et al. Treatment of 153 Japanese patients with Q-switched alexandrite laser. Lasers Med Sci. 2007;22:159-63 pubmed
    ..As a whole, good therapeutic outcome was achieved after multiple treatment sessions. However, the use of other lasers or other treatment modalities should be considered to treat nevus spilus/café-au-lait spots...
  28. Ashrafi M, Shabanian R, Mohammadi M, Kavusi S. Extensive Mongolian spots: a clinical sign merits special attention. Pediatr Neurol. 2006;34:143-5 pubmed
    ..Findings of generalized Mongolian spots in newborns may lead to an early detection and early treatment before irreversible organ damage occurs...
  29. Snow T. Mongolian spots in the newborn: do they mean anything?. Neonatal Netw. 2005;24:31-3 pubmed
    ..Recently, however, there have been studies suggesting that Mongolian spots manifest more often in children with certain inborn errors of metabolism, including mucopolysaccharidosis and GM1 gangliosidosis...