tonsillar neoplasms

Summary

Summary: Tumors or cancer of the PALATINE TONSIL.

Top Publications

  1. Venuti A, Badaracco G, Rizzo C, Mafera B, Rahimi S, Vigili M. Presence of HPV in head and neck tumours: high prevalence in tonsillar localization. J Exp Clin Cancer Res. 2004;23:561-6 pubmed
    ..The results suggest that HPV16 is actively involved in the genesis of a subset of head and neck cancers and that the tonsillar localization may be considered a hot spot for viral transformation...
  2. Hafkamp H, Manni J, Haesevoets A, Voogd A, Schepers M, Bot F, et al. Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas. Int J Cancer. 2008;122:2656-64 pubmed publisher
    ..These findings indicate that oncogenic processes in the tonsils of non-smokers differ from those occurring in smokers, the former being related to HPV 16 infection...
  3. Näsman A, Attner P, Hammarstedt L, Du J, Eriksson M, Giraud G, et al. Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma?. Int J Cancer. 2009;125:362-6 pubmed publisher
    ..In conclusion, the incidence of HPV-positive cancers is still increasing in the County of Stockholm, suggesting an epidemic of a virus-induced carcinoma, with soon practically all tonsillar SCC being HPV positive, as in cervical cancer...
  4. Lindquist D, Romanitan M, Hammarstedt L, Näsman A, Dahlstrand H, Lindholm J, et al. Human papillomavirus is a favourable prognostic factor in tonsillar cancer and its oncogenic role is supported by the expression of E6 and E7. Mol Oncol. 2007;1:350-5 pubmed publisher
    ..Moreover, E6 and/or E7 were expressed in almost all assessable HPV-16 positive cases, supporting an oncogenic role of HPV-16 in tonsillar cancer...
  5. Golas S. Trends in palatine tonsillar cancer incidence and mortality rates in the United States. Community Dent Oral Epidemiol. 2007;35:98-108 pubmed
    ..The purpose of this paper is to describe the extent of the public health problem presented by palatine tonsillar cancer in the United States by analyzing recent incidence and mortality rate trends...
  6. Shiboski C, Schmidt B, Jordan R. Tongue and tonsil carcinoma: increasing trends in the U.S. population ages 20-44 years. Cancer. 2005;103:1843-9 pubmed
    ..The objective of the current study was to explore the trends in both oral cavity and pharyngeal squamous cell carcinoma (SCC) in younger U.S. populations, in particular tongue and tonsillar SCC...
  7. Hammarstedt L, Lu Y, Marklund L, Dalianis T, Munck Wikland E, Ye W. Differential survival trends for patients with tonsillar, base of tongue and tongue cancer in Sweden. Oral Oncol. 2011;47:636-41 pubmed publisher
    ..Further studies are warranted to elucidate more effective treatment options for tongue cancer patients...
  8. Güvenç M, Ada M, Acioglu E, Pamukçu M. Tonsillar metastasis of primary signet-ring cell carcinoma of the cecum. Auris Nasus Larynx. 2006;33:85-8 pubmed
    ..Primary manifestation of these tumors as a tonsillar mass is extremely rare in the literature. We present a case with a tonsillar metastasis from unusually localized primary signet ring-cell carcinoma of the cecum...
  9. Price T, Pickles J. Synchronous bilateral tonsillar carcinoma: role of fluoro-deoxyglucose positron emission tomography scanning in detecting occult primary tumours in metastatic nodal disease of the head and neck. J Laryngol Otol. 2006;120:334-7 pubmed

More Information

Publications83

  1. Magill J, Ferguson M, Butler C, Sandison A, Grant W. Inflammatory myofibroblastic tumour of the tonsil: case report and literature review. J Laryngol Otol. 2010;124:1123-5 pubmed publisher
    ..We present the first reported case in the English language literature of an inflammatory myofibroblastic tumour of the right tonsil in a young, pregnant woman, and we report a management strategy for this enigmatic entity...
  2. Aydin E, Ozluoglu L, Demirhan B, Arikan U. Follicular dendritic cell sarcoma of the tonsil: case report. Eur Arch Otorhinolaryngol. 2006;263:1155-7 pubmed
    ..Without a high index of suspicion, this entity can easily be missed. We believe that follicular dendritic cell sarcoma should be included in the differential diagnosis for any tonsillar mass...
  3. Hobbs C, Sterne J, Bailey M, Heyderman R, Birchall M, Thomas S. Human papillomavirus and head and neck cancer: a systematic review and meta-analysis. Clin Otolaryngol. 2006;31:259-66 pubmed
    ..However, the method of viral detection may be an important source of heterogeneity. Resolution of this issue will require further studies using both methods, examining associations separately in different sites...
  4. Hoffmann M, Ihloff A, Görögh T, Weise J, Fazel A, Krams M, et al. p16(INK4a) overexpression predicts translational active human papillomavirus infection in tonsillar cancer. Int J Cancer. 2010;127:1595-602 pubmed publisher
  5. Hammarstedt L, Lindquist D, Dahlstrand H, Romanitan M, Dahlgren L, Joneberg J, et al. Human papillomavirus as a risk factor for the increase in incidence of tonsillar cancer. Int J Cancer. 2006;119:2620-3 pubmed
    ..Hence, HPV may play an important role for the increased incidence of tonsillar cancer. This should definitely influence future preventive strategies as well as treatment for this type of cancer...
  6. Na I, Kang H, Cho S, Koh J, Lee J, Lee B, et al. EGFR mutations and human papillomavirus in squamous cell carcinoma of tongue and tonsil. Eur J Cancer. 2007;43:520-6 pubmed
    ..Clinical features of lung cancer patients with EGFR mutations were not observed in HNSCC. A further study will be needed to confirm these results...
  7. Hammarstedt L, Dahlstrand H, Lindquist D, Onelöv L, Ryott M, Luo J, et al. The incidence of tonsillar cancer in Sweden is increasing. Acta Otolaryngol. 2007;127:988-92 pubmed
    ..In women, however, smoking can be a part of the explanation. Further studies to look at changes in other environmental factors, such as human papilloma virus (HPV) infection, are clearly warranted...
  8. Sheng L, Zhang L, Xu H, Zhu Y. Ascending colon adenocarcinoma with tonsillar metastasis: a case report and review of the literature. World J Gastroenterol. 2008;14:7138-40 pubmed
    ..The patient was treated with palliative radiotherapy and chemotherapy. He was still alive when we wrote this paper. Our case shows that immunohistochemical diagnosis of metastatic palatine tonsil cancer is essential...
  9. Chien C, Su C, Fang F, Huang H, Chuang H, Chen C, et al. Lower prevalence but favorable survival for human papillomavirus-related squamous cell carcinoma of tonsil in Taiwan. Oral Oncol. 2008;44:174-9 pubmed
    ..In conclusion, the prevalence of HPV-related TSCC is much lower in Taiwan comparing with the Western population, and the prognosis of HPV-positive TSCC is better than that of HPV-negative TSCC...
  10. Li W, Tran N, Lee S, O Brien C, Tse G, Scolyer R, et al. New evidence for geographic variation in the role of human papillomavirus in tonsillar carcinogenesis. Pathology. 2007;39:217-22 pubmed
    ..This study provides the first data on HPV in tonsillar cancers from Hong Kong...
  11. Park K, Park Y. Tonsillar metastasis of signet-ring cell adenocarcinoma of the colon. Ear Nose Throat J. 2010;89:376-7 pubmed
    ..The manner in which tonsillar metastases evolve is still unknown, but some hypotheses have been proposed, and we briefly review these theories...
  12. Sundaram K, Schwartz J, Har El G, Lucente F. Carcinoma of the oropharynx: factors affecting outcome. Laryngoscope. 2005;115:1536-42 pubmed
    ..It was hypothesized that the subsite has a significant impact on outcome...
  13. Hong A, Dobbins T, Lee C, Jones D, Harnett G, Armstrong B, et al. Human papillomavirus predicts outcome in oropharyngeal cancer in patients treated primarily with surgery or radiation therapy. Br J Cancer. 2010;103:1510-7 pubmed publisher
    ..This study examines the prognostic significance of human papillomavirus (HPV) in patients with locally advanced oropharyngeal squamous cell carcinoma (SCC) treated primarily with surgery or definitive radiotherapy...
  14. Vauleon E, de Lajarte Thirouard A, Boucher E, Le Prise E, Guihaire P, Raoul J. Tonsillar metastasis revealing signet-ring cell carcinoma of the rectum. Gastroenterol Clin Biol. 2005;29:70-2 pubmed
    ..Tonsil metastasis is rare and generally develops from primary gastric or colorectal cancer, predominantly poorly-differentiated or signet-ring cell adenocarcinomas...
  15. Wittekindt C, Gültekin E, Weissenborn S, Dienes H, Pfister H, Klussmann J. Expression of p16 protein is associated with human papillomavirus status in tonsillar carcinomas and has implications on survival. Adv Otorhinolaryngol. 2005;62:72-80 pubmed
    ..02). These data indicate that p16 is a technically simple immunohistological marker, applicable for routine pathological histology, and its prognostic value for survival is fully equivalent to HPV DNA detection...
  16. Idrees M, Brandwein Gensler M, Strauchen J, Gil J, Wang B. Extranodal follicular dendritic cell tumor of the tonsil: report of a diagnostic pitfall and literature review. Arch Otolaryngol Head Neck Surg. 2004;130:1109-13 pubmed
    ..We wish to highlight this potential diagnostic pitfall because the treatment and prognosis for FDCT are vastly different from the treatment and prognosis for squamous cell carcinoma of the tonsil...
  17. Hannisdal K, Schjølberg A, De Angelis P, Boysen M, Clausen O. Human papillomavirus (HPV)-positive tonsillar carcinomas are frequent and have a favourable prognosis in males in Norway. Acta Otolaryngol. 2010;130:293-9 pubmed publisher
    ..This study confirms a high prevalence of human papillomavirus (HPV)-positive tonsillar tumours (52%). The survival of the HPV-positive group was significantly better in males...
  18. Mellin Dahlstrand H, Lindquist D, Björnestål L, Ohlsson A, Dalianis T, Munck Wikland E, et al. P16(INK4a) correlates to human papillomavirus presence, response to radiotherapy and clinical outcome in tonsillar carcinoma. Anticancer Res. 2005;25:4375-83 pubmed
    ..Here, p16(INK4A), in situ HPV DNA hybridisation (ISH) and HPVL1 capsid detection were evaluated in tonsillar carcinoma to predict the response to radiotherapy (RT) and prognosis...
  19. El Mofty S, Lu D. Prevalence of human papillomavirus type 16 DNA in squamous cell carcinoma of the palatine tonsil, and not the oral cavity, in young patients: a distinct clinicopathologic and molecular disease entity. Am J Surg Pathol. 2003;27:1463-70 pubmed
    ..The HPV-positive carcinomas have a distinct histopathologic and immunophenotypic features...
  20. Mellin H, Friesland S, Lewensohn R, Dalianis T, Munck Wikland E. Human papillomavirus (HPV) DNA in tonsillar cancer: clinical correlates, risk of relapse, and survival. Int J Cancer. 2000;89:300-4 pubmed
    ..These results indicate that HPV status is a significantly favorable prognostic factor in tonsillar cancer and may be used as a marker in order to optimize the treatment of patients with this type of cancer...
  21. Botsios C, Ostuni P, Boscolo Rizzo P, Da Mosto M, Punzi L, Marchiori C. Dermatomyositis and malignancy of the pharynx in Caucasian patients: report of two observations. Rheumatol Int. 2003;23:309-11 pubmed
    ..We report two cases of Caucasian Italian patients with dermatomyositis associated, respectively, with nasopharyngeal and tonsillar carcinomas. The relationship between dermatomyositis and malignancy is also discussed...
  22. Li W, Thompson C, Xin D, Cossart Y, O Brien C, McNeil E, et al. Absence of human papillomavirus in tonsillar squamous cell carcinomas from Chinese patients. Am J Pathol. 2003;163:2185-9 pubmed
    ..They also support the hypothesis that molecular pathways to tonsil cancer mediated by HPV are distinct from those induced by mutagens present in cigarette smoke or alcohol...
  23. Dahlstrand H, Dahlgren L, Lindquist D, Munck Wikland E, Dalianis T. Presence of human papillomavirus in tonsillar cancer is a favourable prognostic factor for clinical outcome. Anticancer Res. 2004;24:1829-35 pubmed
    ..However, HPV-positive cancer exhibits less genetic instability i.e. shows a lower degree of aneuploidy and a tendency to have fewer chromosomal aberrations, when compared to HPV-negative tonsillar cancer...
  24. Syrjanen S. HPV infections and tonsillar carcinoma. J Clin Pathol. 2004;57:449-55 pubmed
    ..They are also younger and the association with conventional risk factors-smoking and drinking-is less significant than in HPV negative patients. Thus, recent data suggest a distinct pattern for HPV-16 positive TCs...
  25. Mendenhall W, Amdur R, Stringer S, Villaret D, Cassisi N. Radiation therapy for squamous cell carcinoma of the tonsillar region: a preferred alternative to surgery?. J Clin Oncol. 2000;18:2219-25 pubmed
    ..The purpose of this study was to evaluate the results of RT alone and RT combined with a planned neck dissection for carcinoma of the tonsillar area and to compare these data with the results of treatment with primary surgery...
  26. Tisch M, Hengstermann F, Kraft K, von Hinüber G, Maier H. Follicular dendritic cell sarcoma of the tonsil: report of a rare case. Ear Nose Throat J. 2003;82:507-9 pubmed
    ..After more than 5 years of follow-up, the patient showed no evidence of recurrence. We also discuss the salient features of the immunohistochemical examination...
  27. Li W, Thompson C, O Brien C, McNeil E, Scolyer R, Cossart Y, et al. Human papillomavirus positivity predicts favourable outcome for squamous carcinoma of the tonsil. Int J Cancer. 2003;106:553-8 pubmed
    ..Screening of tonsil cancers for HPV DNA may help optimise treatment and provide more accurate prognostic information...
  28. Klussmann J, Gültekin E, Weissenborn S, Wieland U, Dries V, Dienes H, et al. Expression of p16 protein identifies a distinct entity of tonsillar carcinomas associated with human papillomavirus. Am J Pathol. 2003;162:747-53 pubmed
    ..02). These data indicate that p16 is a technically simple immunohistological marker, applicable for routine pathological histology, and its prognostic value for survival is fully equivalent to HPV-DNA detection...
  29. Mellin H, Dahlgren L, Munck Wikland E, Lindholm J, Rabbani H, Kalantari M, et al. Human papillomavirus type 16 is episomal and a high viral load may be correlated to better prognosis in tonsillar cancer. Int J Cancer. 2002;102:152-8 pubmed
    ..In conclusion, HPV-16 is mainly episomal in tonsillar cancer. The viral load showed a wide distribution and the clinical outcome in our study was better when the HPV load was higher...
  30. Strome S, Savva A, Brissett A, Gostout B, Lewis J, Clayton A, et al. Squamous cell carcinoma of the tonsils: a molecular analysis of HPV associations. Clin Cancer Res. 2002;8:1093-100 pubmed
    ..The role of human papilloma virus (HPV) in the pathogenesis and biological behavior of tonsillar squamous cell carcinoma (TSCC) are areas of intense investigation...
  31. Klussmann J, Weissenborn S, Wieland U, Dries V, Kolligs J, Jungehuelsing M, et al. Prevalence, distribution, and viral load of human papillomavirus 16 DNA in tonsillar carcinomas. Cancer. 2001;92:2875-84 pubmed
    ..The authors determined the load and localization of HPV DNA in a subset of tonsillar carcinomas and their metastases...
  32. Hurlstone D, Sanders D, Smith A, Jones R, Slater D, Bardhan K. Tonsillar metastasis: A rare presentation of gastric carcinoma. Eur J Surg Oncol. 2001;27:328-30 pubmed
    ..We describe only the second reported case of tonsillar metastasis as a presenting feature of gastric carcinoma. A review of the literature is also discussed...
  33. Frisch M, Hjalgrim H, Jaeger A, Biggar R. Changing patterns of tonsillar squamous cell carcinoma in the United States. Cancer Causes Control. 2000;11:489-95 pubmed
    ..Tonsillar squamous cell carcinoma (SCC) may differ etiologically from other oral cancers. The aim of this study was to provide a detailed description of the incidence patterns of tonsillar SCC in the United States...
  34. Rotnáglová E, Tachezy R, Salakova M, Prochazka B, Košl abová E, Vesela E, et al. HPV involvement in tonsillar cancer: prognostic significance and clinically relevant markers. Int J Cancer. 2011;129:101-10 pubmed publisher
  35. Meyer T, Guntinas Lichius O, von Eggeling F, Ernst G, Akimov D, Schmitt M, et al. Multimodal nonlinear microscopic investigations on head and neck squamous cell carcinoma: toward intraoperative imaging. Head Neck. 2013;35:E280-7 pubmed publisher
    ..By integration into an operational microscope, routine screening of suspicious lesions and surgical guidance can be realized. ..
  36. Lee H, Kim J, Roh J, Lee J, Cho K, Park G, et al. Utility of quantitative 18 F-fluorodeoxyglucose uptake measurement to identify occult tonsillar carcinoma in patients with cervical metastasis of unknown primary tumours: a retrospective case-control study. Clin Otolaryngol. 2013;38:30-8 pubmed publisher
    ..06) and D (1.16) (P < 0.01). (18) F-fluorodeoxyglucose positron emission tomography/computerised tomography with tonsil SUVmax measurement is useful to identify occult tonsillar squamous cell carcinoma. ..
  37. Weinstein G, O Malley B, Snyder W, Sherman E, Quon H. Transoral robotic surgery: radical tonsillectomy. Arch Otolaryngol Head Neck Surg. 2007;133:1220-6 pubmed
    ..Radical tonsillectomy using TORS is a new technique that offers excellent access for resection of carcinomas of the tonsil with acceptable acute morbidity. Future reports will focus on long-term oncologic and functional outcomes. ..
  38. Oh S, Kim W, Kim J, Kim S, Lee S, Lee D, et al. Waldeyer's ring marginal zone B cell lymphoma: are the clinical and prognostic features nodal or extranodal? A study by the Consortium for Improving Survival of Lymphoma (CISL). Int J Hematol. 2012;96:631-7 pubmed publisher
    ..4 and 90.5 %, respectively. In a comparison with the historical data regarding extra-WR MALT lymphoma and nodal MZL (N-MZL), MALT lymphoma showed better TTP results than did WR-MZL and N-MZL (P < 0.001). ..
  39. Hofmann U, O Connor J, Biyani C, Harnden P, Selby P, Weston P. Retroperitoneal metastatic squamous cell carcinoma of the tonsil (with elevated beta human chorionic gonadotrophin): a misdiagnosis as extra-gonadal germ cell tumour. J Laryngol Otol. 2006;120:885-7 pubmed
    ..This case highlights the necessity of using clinical, histological, immunohistological and ultrastructural examination to establish precise diagnosis and to avoid inappropriate treatment. ..
  40. Kimura Y, Yano K, Kamiyama R, Kishimoto S. [Case of cystic metastasis of lingual tonsil carcinoma diagnosed first as a branchiogenic cyst]. Nihon Jibiinkoka Gakkai Kaiho. 2005;108:698-701 pubmed
    ..The diagnosis of the primary unknown cystic metastatic cervieal SCC requires a thorough examination of the palatine or lingual tonsil when there is no evidence of any vestigial remnant of branchiogenic organ...
  41. Mortensen G, Paaske P. Patients perceive tonsil cancer as a strike at psycho-socially "vital organs". Dan Med J. 2012;59:A4504 pubmed
    ..These QoL effects ought to be included in future considerations of HPV vaccination of boys as well as girls. The study was funded by an unrestricted research grant from Sanofi Pasteur MSD. not relevant. ..
  42. Maruzzo M, Giorgi C, Marioni G, Bottin R, Zanon S, Marino F, et al. Late onset (22 years) of simultaneous tonsillar and cervical lymph node metastases from breast ductal carcinoma. Am J Otolaryngol. 2012;33:627-30 pubmed publisher
    ..Tonsil metastases from breast cancer are extremely rare. Herein, we report a case of a 74-year-old woman with simultaneous occurrence of tonsillar and cervical lymph nodes metastases after a disease-free interval of 22 years. ..
  43. Kwon M, Kwon J, Nam E, Shin H, Lee D, Kim J, et al. TWIST1 promoter methylation is associated with prognosis in tonsillar squamous cell carcinoma. Hum Pathol. 2013;44:1722-9 pubmed publisher
    ..TWIST1 promoter hypermethylation may be a useful molecular marker for predicting prognoses and contralateral cervical lymph node metastases in patients with TSCC. ..
  44. Evans M, Matthews A, Kandil D, Adamson C, Trotman W, Cooper K. Discrimination of 'driver' and 'passenger' HPV in tonsillar carcinomas by the polymerase chain reaction, chromogenic in situ hybridization, and p16(INK4a) immunohistochemistry. Head Neck Pathol. 2011;5:344-8 pubmed publisher
    ..The clinical significance of TSCCs that test HPV negative/p16(INK4a) positive, PCR and CISH HPV positive/p16 (INK4a) negative, or PCR HPV positive/p16 (INK4a) and CISH negative, also requires further investigation. ..
  45. Jumper J, Fischbein N, Kaplan M, Klein H, Dillon W. The "small, dark tonsil" in patients presenting with metastatic cervical lymphadenopathy from an unknown primary. AJNR Am J Neuroradiol. 2005;26:411-3 pubmed
    ..We present the "small, dark tonsil" as an alternative imaging presentation of SCC and a new sign to look for when evaluating the patient with metastatic lymphadenopathy from an unknown primary tumor. ..
  46. Howe D, Henderson M, Ahmad I. Superior sagittal sinus thrombosis complicating neck dissection. J Laryngol Otol. 2010;124:1126-8 pubmed publisher
    ..Dominant internal jugular vein anatomy may be evident on pre-operative imaging. An awareness of this complication may be helpful to surgeons contemplating sacrifice of the internal jugular vein. ..
  47. Lee H, Chong Y, Cheng Y. Invasive Streptococcus agalactiae septic arthritis as an initial presentation of tonsillar carcinoma. Singapore Med J. 2007;48:678-81 pubmed
  48. Studer G, Glanzmann C. Volumetric staging in oropharyngeal cancer patients treated with definitive IMRT. Oral Oncol. 2013;49:269-76 pubmed publisher
    ..Aim of this work was to specifically assess the prognostic value of VS in oropharyngeal cancer (OC)...
  49. Du J, Nordfors C, N sman A, Sobkowiak M, Romanitan M, Dalianis T, et al. Human papillomavirus (HPV) 16 E6 variants in tonsillar cancer in comparison to those in cervical cancer in Stockholm, Sweden. PLoS ONE. 2012;7:e36239 pubmed publisher
    ..Alternatively, there could be differences with regard to the oral and cervical prevalence of this variant that need to be explored further...
  50. Jansen J, Schoder H, Lee N, Stambuk H, Wang Y, Fury M, et al. Tumor metabolism and perfusion in head and neck squamous cell carcinoma: pretreatment multimodality imaging with 1H magnetic resonance spectroscopy, dynamic contrast-enhanced MRI, and [18F]FDG-PET. Int J Radiat Oncol Biol Phys. 2012;82:299-307 pubmed publisher
    ..Additionally, combined DCE-MRI and [(18)F]FDG PET parameters were predictive of short-term response to treatment. ..
  51. Kohl S, Simpson R, Wisecarver J. Chondroid metaplasia mimicking recurrent squamous cell carcinoma of the head and neck. Ear Nose Throat J. 2009;88:E4 pubmed
    ..Chondroid metaplasia involving the head and neck is rare. When it has occurred, it has been seen in both reactive and neoplastic settings. To our knowledge, this is the first reported case of a chondroid metaplasia of the tongue. ..
  52. Saba N, Goodman M, Ward K, Flowers C, Ramalingam S, Owonikoko T, et al. Gender and ethnic disparities in incidence and survival of squamous cell carcinoma of the oral tongue, base of tongue, and tonsils: a surveillance, epidemiology and end results program-based analysis. Oncology. 2011;81:12-20 pubmed publisher
    ..The differences in outcomes across ethnic origin groups are also described and discussed. ..
  53. Grant J, North S. Evaluation of the factors contributing to long-term survival in canine tonsillar squamous cell carcinoma. Aust Vet J. 2016;94:197-202 pubmed publisher
    ..There was no clear association between long survival and additional surgeries for progressive disease; however; further investigation is warranted. ..
  54. Tsujioka T, Wada H, Suemori S, Sadahira Y, Sugihara T. [CD56-positive peripheral T-cell lymphoma primarily presenting with tonsillar swelling]. Rinsho Ketsueki. 2004;45:1119-23 pubmed
    ..Because small bowel ulcers were revealed during the course of induction chemotherapy, we report a valuable case in which suspected CD56-positive enteropathy-type T-cell lymphoma (ETL) occurred primarily in the tonsils. ..
  55. Osuch Wójcikiewicz E, Rzepakowska A, Bruzgielewicz A, Wieczorek J. [Follicular (nodular) non Hodgkin's lymphoma of tonsil--case report]. Otolaryngol Pol. 2007;61:203-6 pubmed
    ..The vast majority of NHL at this site are B-cell lymphomas, including diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, extranodal marginal zone B-cell of MALT type...
  56. Cobo F, Talavera P, Concha A. Review article: relationship of human papillomavirus with papillary squamous cell carcinoma of the upper aerodigestive tract: a review. Int J Surg Pathol. 2008;16:127-36 pubmed publisher
    ..This association should be clearly established to make a correct diagnosis and propose the best therapeutic strategies, such as new vaccines...
  57. Salplahta D, Comănescu M, Anghelina F, Ioniţă E, Mogoantă C, Anghelina L. Non-Hodgkin lymphomas of Waldeyer's ring. Rom J Morphol Embryol. 2012;53:1057-60 pubmed
    ..Good knowledge of the clinical characteristics of these lymphomas and the methods to establish the differential diagnosis are essential for a correct therapy of the disease...
  58. Richard P, Vassallo J, Valmary S, Missoury R, Delsol G, Brousset P. "In situ-like" mantle cell lymphoma: a report of two cases. J Clin Pathol. 2006;59:995-6 pubmed
    ..To the best of our knowledge, this is the first report on such a pattern of MCL, which is important to recognise, as it can be confused with lymphoid hyperplasia...
  59. Baize A, Sculier J, Dusarf M, Berghmans T. [Cardiac arrest during TEP-scan]. Rev Med Brux. 2009;30:111-3 pubmed
    ..A 72 year-old man presenting with a tonsil neoplasm developed a cardiac arrest when performing a positron emission tomography with tomodensitometry (18F-FDG-PET). The final diagnosis is obtained after interpretation of the PET-CT images...
  60. Han T, Wang L, Fan L, Xu J, Li J, Xu W. [Clinical pathological analysis of 7 cases of primary tonsil diffuse large B cell lymphoma]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2014;22:104-7 pubmed publisher
  61. Le Scodan R, Pommier P, Ardiet J, Montbarbon X, Malet C, Favrel V, et al. Exclusive brachytherapy for T1 and T2 squamous cell carcinomas of the velotonsillar area: results in 44 patients. Int J Radiat Oncol Biol Phys. 2005;63:441-8 pubmed
    ..To evaluate the role of interstitial brachytherapy as an exclusive radiotherapy modality for primary T1-T2 squamous cell carcinomas (SCC) of the velotonsillar area...
  62. Bachar G, Goh C, Goldstein D, O Sullivan B, Irish J. Long-term outcome analysis after surgical salvage for recurrent tonsil carcinoma following radical radiotherapy. Eur Arch Otorhinolaryngol. 2010;267:295-301 pubmed publisher
    ..Despite the poor prognosis, 20% of patients will be alive at 5 years and therefore salvage surgery should be considered when possible...
  63. Fasanmade A, Farrell K, Perkins C. Bazex syndrome (acrokeratosis paraneoplastica): persistence of cutaneous lesions after successful treatment of an associated oropharyngeal neoplasm. Br J Oral Maxillofac Surg. 2009;47:138-9 pubmed publisher
    ..We report a case associated with SCC of the right tonsil with persistent paraneoplastic cutaneous lesions 2 years after successful treatment of the underlying neoplasm...
  64. van der Vorst J, Schaafsma B, Verbeek F, Keereweer S, Jansen J, van der Velden L, et al. Near-infrared fluorescence sentinel lymph node mapping of the oral cavity in head and neck cancer patients. Oral Oncol. 2013;49:15-9 pubmed publisher
    ..This feasibility study explored the use of indocyanine green adsorbed to human serum albumin (ICG:HSA) for SLN mapping in head and neck cancer patients...
  65. Mas A, Blackwood L, Cripps P, Murphy S, De Vos J, Dervisis N, et al. Canine tonsillar squamous cell carcinoma -- a multi-centre retrospective review of 44 clinical cases. J Small Anim Pract. 2011;52:359-64 pubmed publisher
    ..To review the presenting clinical signs, treatment and survival of dogs with tonsillar squamous cell carcinoma and, if possible, to identify useful prognostic indicators...
  66. Aung N, Ohtake H, Iwaba A, Kato T, Ohe R, Tajima K, et al. Angioimmunoblastic T-cell lymphoma with dual genotype of TCR and IgH genes. Pathol Res Pract. 2011;207:317-21 pubmed publisher
    ..We here report a rare case of AITL involving palatine tonsil as primary site and give a review of the literature...
  67. Teh C, Jayalakshmi P, Chong S. Waldeyer ring lymphoma: a case series. Ear Nose Throat J. 2014;93:E22-5 pubmed
    ..There were 14 patients (47%) alive at the end of the study period. ..
  68. Vojtěchová Z, Zavadil J, Klozar J, Grega M, Tachezy R. Comparison of the miRNA expression profiles in fresh frozen and formalin-fixed paraffin-embedded tonsillar tumors. PLoS ONE. 2017;12:e0179645 pubmed publisher
  69. Yu G, Mehta V, Branovan D, Huang Q, Hashibe M, Zhang Z, et al. Improved survival among patients with base of tongue and tonsil cancer in the United States. Cancer Causes Control. 2012;23:153-64 pubmed publisher
    ..To examine if survival has changed over the last 20 years in patients with base of tongue and tonsil cancers in the United States...
  70. Mønsted J. [Bilateral squamous cell carcinoma of the tonsils]. Ugeskr Laeger. 2010;172:3417-8 pubmed
    ..Furthermore, we indicate that synchronous cancers are not that rare, and that special care should be taken when examining a patient with a squamous cell carcinoma of the oropharynx...
  71. Pedruzzi P, Kowalski L, Nishimoto I, Oliveira B, Tironi F, Ramos G. Analysis of prognostic factors in patients with oropharyngeal squamous cell carcinoma treated with radiotherapy alone or in combination with systemic chemotherapy. Arch Otolaryngol Head Neck Surg. 2008;134:1196-204 pubmed publisher
    ..To assess the prognostic significance of several factors in oropharyngeal squamous cell carcinoma treated with radiotherapy alone or in combination with chemotherapy...
  72. Haddad R, Crum C, Chen Z, Krane J, Posner M, Li Y, et al. HPV16 transmission between a couple with HPV-related head and neck cancer. Oral Oncol. 2008;44:812-5 pubmed
    ..An uncommon signal variant nucleotide was identified in both genomes that is not present in the HPV16R. These tumors likely represent transmission between the couple...
  73. Mogoantă C, Ion D, Stanciu G, Ioniţă E, Bold A, Mateescu G, et al. The importance of tumor proliferation markers in assessing lesions of the palatine tonsil. Rom J Morphol Embryol. 2011;52:1033-9 pubmed
    ..By using immunohistochemical markers in the histopathological examination the diagnosis is improved, leading to a more appropriate therapeutical approach...
  74. Sunkaraneni V, Jones S, Prasai A, Fish B. Is unilateral tonsillar enlargement alone an indication for tonsillectomy?. J Laryngol Otol. 2006;120:E21 pubmed
    ..Frequently, these patients are listed for tonsillectomy for the purpose of ruling out malignant histology. This study aims to determine the necessity for tonsillectomy...