ear neoplasms

Summary

Summary: Tumors or cancer of any part of the hearing and equilibrium system of the body (the EXTERNAL EAR, the MIDDLE EAR, and the INNER EAR).

Top Publications

  1. Barrs D. Temporal bone carcinoma. Otolaryngol Clin North Am. 2001;34:1197-218, x pubmed
    ..This article summarizes clinical manifestations, differential diagnosis, management, and differences in treatment philosophy...
  2. Jan J, Wang C, Kwan P, Wu S, Shu H. Ceruminous adenocarcinoma with extensive parotid, cervical, and distant metastases: case report and review of literature. Arch Otolaryngol Head Neck Surg. 2008;134:663-6 pubmed publisher
  3. Bell D, Gidley P, Levine N, Fuller G. Endolymphatic sac tumor (aggressive papillary tumor of middle ear and temporal bone): sine qua non radiology-pathology and the University of Texas MD Anderson Cancer Center experience. Ann Diagn Pathol. 2011;15:117-23 pubmed publisher
    ..Precise preoperative anatomic localization and computed tomography and magnetic resonance imaging feature interpretation play a paramount role in achieving an accurate final diagnosis...
  4. Kojima H, Yaguchi Y, Moriyama H. Middle ear hemangiona: a case report. Auris Nasus Larynx. 2008;35:255-9 pubmed
    ..The CT, MRI, angiography, and light microscopy findings of the tumor are documented and compared with those a glomus tumor. The significance of this diagnosis is also discussed...
  5. Okada T, Saito K, Takahashi M, Hasegawa Y, Fujimoto Y, Terada A, et al. En bloc petrosectomy for malignant tumors involving the external auditory canal and middle ear: surgical methods and long-term outcome. J Neurosurg. 2008;108:97-104 pubmed publisher
    ..The aim of this study was to describe a method for resecting malignant tumors originating in the external auditory canal or middle ear and requiring en bloc resection of the petrous bone...
  6. Selcuk A, Ensari S, Cetin M, Sak S, Dere H. Ceruminous gland carcinoma of the external auditory canal presenting as chronic otitis media. B-ENT. 2007;3:195-9 pubmed
    ..We report a case of carcinoma originating from the ceruminous glands of the external ear canal (EAC), operated based on a diagnosis of chronic otitis media with polyp...
  7. Covelli E, De Seta E, Zardo F, De Seta D, Filipo R. Cavernous haemangioma of external ear canal. J Laryngol Otol. 2008;122:e19 pubmed publisher
    ..The aim of this study was to document the occurrence of a cavernous haemangioma of the external auditory canal, and to review the literature on this pathology...
  8. Tanaka H, Kohno A, Gomi N, Matsueda K, Mitani H, Kawabata K, et al. Malignant mucosal melanoma of the eustachian tube. Radiat Med. 2008;26:305-8 pubmed publisher
    ..Although the head and neck region is the most common site for mucosal melanoma, a melanoma arising in the eustachian tube is rare. Here we present a case of mucosal melanoma arising in the right eustachian tube...
  9. Dong F, Gidley P, Ho T, Luna M, Ginsberg L, Sturgis E. Adenoid cystic carcinoma of the external auditory canal. Laryngoscope. 2008;118:1591-6 pubmed publisher
    ..To describe the clinical history and outcome of patients with adenoid cystic carcinoma (ACC) of the external auditory canal (EAC)...

More Information

Publications62

  1. Yang B, Wang Z, Xian J, Chen Q. MR imaging features of primary mucosal melanoma of the eustachian tube: report of 2 cases. AJNR Am J Neuroradiol. 2009;30:431-3 pubmed publisher
    ..We discuss the value of using MR imaging to diagnose and treat patients with melanoma in the eustachian tube. In addition, we introduce the key points to differentiate melanoma from some common diseases in the region...
  2. Rutherford K, Leonard G. Hemangiomas of the external auditory canal. Am J Otolaryngol. 2010;31:384-6 pubmed publisher
    ..In addition, we review the relevant literature with respect to epidemiology, presentation, evaluation, pathology, and management options for hemangiomas arising in the external auditory canal...
  3. Skalova A, Sima R, Bohus P, Curik R, Lukas J, Michal M. Endolymphatic sac tumor (aggressive papillary tumor of middle ear and temporal bone): report of two cases with analysis of the VHL gene. Pathol Res Pract. 2008;204:599-606 pubmed publisher
    ..This mutation is a C to T exchange at position 194, resulting in amino acid exchange S65L. No mutation was found in any of the three exons analyzed and in the exon-intron junctions of the VHL gene in the sporadic case...
  4. Michaels L. Origin of endolymphatic sac tumor. Head Neck Pathol. 2007;1:104-11 pubmed publisher
    ..Care should be taken in the evaluation of surgical or autopsy material from EDSs not to overcall any of these normal features as malignant...
  5. Moore M, Deschler D, McKenna M, Varvares M, Lin D. Management outcomes following lateral temporal bone resection for ear and temporal bone malignancies. Otolaryngol Head Neck Surg. 2007;137:893-8 pubmed
    ..To evaluate clinical outcomes following lateral temporal bone resection (LTBR) for management of malignancies involving the ear or temporal bone...
  6. Yang T, Chiang Y, Chao P, Lee F. Cavernous hemangioma of the bony external auditory canal. Otolaryngol Head Neck Surg. 2006;134:890-1 pubmed
  7. Thompson L. Neuroendocrine adenoma of the middle ear. Ear Nose Throat J. 2005;84:560-1 pubmed
  8. Hiraumi H, Miura M, Hirose T. Capillary hemangioma of the tympanic membrane. Am J Otolaryngol. 2005;26:351-2 pubmed
    ..After surgical treatment, hearing loss was diminished, and there has not been any sign of recurrence for 3 years despite the positive surgical margin...
  9. De Lucia A, Gambardella T, Carra P, Motta G. A case of highly aggressive adenoid cystic carcinoma of the external auditory canal. Acta Otorhinolaryngol Ital. 2004;24:354-6 pubmed
    ..A subtotal petrosectomy combined with homolateral elective lymph node neck dissection was performed. Parotid gland, condyle of the mandible and VII cranial nerve were spared since these were free from disease...
  10. Bambakidis N, Megerian C, Ratcheson R. Differential grading of endolymphatic sac tumor extension by virtue of von Hippel-Lindau disease status. Otol Neurotol. 2004;25:773-81 pubmed
    ..The goal of this study was to use a newly devised classification system as a means to analyze differences between endolymphatic sac tumor extension in von Hippel-Lindau disease and non-von Hippel-Lindau disease patients...
  11. Pulec J, Deguine C. Squamous cell carcinoma of the external auditory canal. Ear Nose Throat J. 2004;83:9 pubmed
  12. Kennedy R, Shelton C, Salzman K, Davidson H, Harnsberger H. Intralabyrinthine schwannomas: diagnosis, management, and a new classification system. Otol Neurotol. 2004;25:160-7 pubmed
    ..To outline the diagnosis and management of intralabyrinthine schwannomas and to propose a new classification system to further define them...
  13. Torske K, Thompson L. Adenoma versus carcinoid tumor of the middle ear: a study of 48 cases and review of the literature. Mod Pathol. 2002;15:543-55 pubmed
    ..Middle ear adenoma most correctly describes their morphologic features and clinical behavior, although neuroendocrine adenoma of the middle ear may be a more accurate designation...
  14. Schrock A, Laffers W, Bootz F. Solitary metastasis of lung carcinoma to the internal auditory canal. Am J Otolaryngol. 2006;27:214-6 pubmed
    ..After tumor resection, the histopathologic examination revealed a metastasis of a squamous cell carcinoma. Computed tomographic scan and bronchoscopy identified an asymptomatic primary pulmonary neoplasm...
  15. Mashkevich G, Undavia S, Iacob C, Arigo J, Linstrom C. Malignant cylindroma of the external auditory canal. Otol Neurotol. 2006;27:97-101 pubmed
    ..This report describes a case of a malignant cylindroma arising in the external auditory canal...
  16. Bared A, Dave S, Garcia M, Angeli S. Mucoepidermoid carcinoma of the external auditory canal (EAC). Acta Otolaryngol. 2007;127:280-4 pubmed
    ..Given the difficulty in detecting mucoepidermoid carcinoma in surgical margins by frozen section analysis, patients should be informed of the possibility of further surgery (re-resection) when a conservative approach is used...
  17. Kupferman M, Bigelow D, Carpentieri D, Bilaniuk L, Kazahaya K. Endolymphatic sac tumor in a 4-year-old boy. Otol Neurotol. 2004;25:782-6 pubmed
    ..Endolymphatic sac tumors (ELST) are rare, low-grade, locally aggressive papillary neoplasms. We present a case of a 4-year-old boy with an ELST, the youngest described in the literature...
  18. Conlin P, Mira J, Graham S, Kaye K, Cordero J. Ceruminous gland adenoid cystic carcinoma with contralateral metastasis to the brain. Arch Pathol Lab Med. 2002;126:87-9 pubmed
    ..This rare neoplasm should be considered in the differential diagnosis of poorly differentiated carcinomas metastatic to the central nervous system in patients with occult malignant neoplasms...
  19. Magliulo G, Fusconi M, Pulice G. Mucoepidermoid carcinoma of the external auditory canal: case report. Am J Otolaryngol. 2003;24:274-7 pubmed
    ..The problems in the diagnosis and the possible methods of treatment of mucoepidermoid carcinoma are discussed...
  20. Limb C, Mabrie D, Carey J, Minor L. Hemangioma of the external auditory canal. Otolaryngol Head Neck Surg. 2002;126:74-5 pubmed
  21. Choi J, Choi E, Lee H, Yoo J, Kim S, Lee W. Mode of parotid involvement in external auditory canal carcinoma. J Laryngol Otol. 2003;117:951-4 pubmed
  22. Hecht D, Jackson C, Grundfast K. Management of middle ear hemangiomas. Am J Otolaryngol. 2001;22:362-6 pubmed
    ..If growth of a middle ear hemangioma appears to be causing complications refractory to conservative therapy, then early surgical excision may be indicated...
  23. Racic G, Kurtovic D, Roje Z, Tomic S, Dogas Z. Primary mucosal melanoma of the eustachian tube. Eur Arch Otorhinolaryngol. 2004;261:139-42 pubmed
    ..The management of the malignant melanoma neck metastasis should also involve endoscopic examination of the upper aerodigestive tract, since the primary lesion can occur there...
  24. Baek S, Song M, Lim B, Lee W. Mucosal melanoma arising in the eustachian tube. J Laryngol Otol. 2006;120:E17 pubmed
    ..Systemic chemotherapy was not utilized in this case; however, it is often used for palliative purposes. A literature review is also presented...
  25. Treasure T. External auditory canal carcinoma involving the temporomandibular joint: two cases presenting as temporomandibular disorders. J Oral Maxillofac Surg. 2002;60:465-9 pubmed
  26. Marques E, Brandis A, Samii M, Tatagiba M. Late metastasis of breast adenocarcinoma into internal auditory canal and cerebellopontine angle: case report. Arq Neuropsiquiatr. 2002;60:639-42 pubmed
    ..Metastasis is a rare occurrence within the IAC and CPA. Clinical history of severe facial palsy will rise suspicion of malignant tumor in spite of the radiological findings...
  27. Davids T, Reid D. Capillary hemangioma of the middle ear. J Otolaryngol. 2006;35:196-9 pubmed
  28. Garbyal R, Kumar M, Bohra A. Adenoid cystic carcinoma of ceruminous gland: a case report. Indian J Pathol Microbiol. 2006;49:587-9 pubmed
  29. Lai C, Tsay S, Ho C. Malignant melanoma of the eustachian tube. J Laryngol Otol. 2001;115:567-9 pubmed
    ..This is an exceedingly rare condition that was treated with endoscopic surgery and post-operative radiotherapy. During a 15-month follow-up, there was no evidence of recurrence...
  30. Hsueh P, Chen W, Chiang Y, Lee F. Capillary hemangioma of the middle ear. Otolaryngol Head Neck Surg. 2007;136:666-7 pubmed
  31. Hirunpat S, Riabroi K, Dechsukhum C, Atchariyasathian V, Tanomkiat W. Nasopharyngeal extension of glomus tympanicum: an unusual clinical and imaging manifestation. AJNR Am J Neuroradiol. 2006;27:1820-2 pubmed
    ..Only 2 cases have been reported in the literature to date. We present a reported case of a large nasopharyngeal extension of recurrent glomus tympanicum, with various kinds of imaging and histopathology and a review of the literature...
  32. Uchida M, Matsunami T. Malignant amelanotic melanoma of the middle ear. Arch Otolaryngol Head Neck Surg. 2001;127:1126-8 pubmed
    ..Although chemohormonal therapy was performed and was slightly effective in reducing the primary tumor, the patient died of acute renal failure. Autopsy confirmed the diagnosis of amelanotic melanoma of the middle ear...
  33. Lonser R, Kim H, Butman J, Vortmeyer A, Choo D, Oldfield E. Tumors of the endolymphatic sac in von Hippel-Lindau disease. N Engl J Med. 2004;350:2481-6 pubmed
  34. Thompson L, Nelson B, Barnes E. Ceruminous adenomas: a clinicopathologic study of 41 cases with a review of the literature. Am J Surg Pathol. 2004;28:308-18 pubmed
    ..Ceruminous gland neoplasms are rare neoplasms. To date, a large clinicopathologic study of benign ceruminous gland neoplasms has not been reported...
  35. Tzagaroulakis A, Pasxalidis J, Papadimitriou N, Boussiotou A, Nikolopoulos T, Korres S, et al. Recurrent ceruminous adenocarcinoma of the external auditory canal. ORL J Otorhinolaryngol Relat Spec. 2003;65:300-2 pubmed
    ..Although recurrences usually occur within months after inadequate management, some may happen even 7 years post treatment. Therefore, routine long-term follow-up was advised...
  36. Tokyol C, Yilmaz M. Middle ear hemangioma: a case report. Am J Otolaryngol. 2003;24:405-7 pubmed
    ..A case of a right-sided middle ear hemangioma in a 51-year-old woman who suffered from pulsatile tinnitus is presented with a review of the relevant literature...
  37. Mohan H, Handa U, Amanjit -, Kotwal S, Dass A. Adenoid cystic carcinoma of the external auditory canal. A case report with diagnosis by fine needle aspiration. Acta Cytol. 2003;47:792-4 pubmed
  38. Devaney K, Ferlito A, Rinaldo A. Epithelial tumors of the middle ear--are middle ear carcinoids really distinct from middle ear adenomas?. Acta Otolaryngol. 2003;123:678-82 pubmed
    ..Dense core neurosecretory granules may be identifiable by electron microscopy. Conservative surgical excision is the treatment of choice, and local recurrence following complete excision is quite uncommon...
  39. Lassaletta L, Patron M, Olóriz J, Perez R, Gavilan J. Avoiding misdiagnosis in ceruminous gland tumours. Auris Nasus Larynx. 2003;30:287-90 pubmed
    ..The benign eccrine cylindroma should be included in the ceruminous gland tumour classification. A wide excisional biopsy should be performed in every EAC lesion. The terms 'ceruminoma' and 'cylindroma' should be avoided...
  40. Nyrop M, Grøntved A. Cancer of the external auditory canal. Arch Otolaryngol Head Neck Surg. 2002;128:834-7 pubmed
    ..To evaluate the outcome of surgery for cancer of the external auditory canal and relate this to the Pittsburgh staging system used both on squamous cell carcinoma and non-squamous cell carcinoma...
  41. Suryanarayanan R, Dezso A, Ramsden R, Gillespie J. Metastatic carcinoma mimicking a facial nerve schwannoma: the role of computerized tomography in diagnosis. J Laryngol Otol. 2005;119:1010-2 pubmed
    ..The case highlights the importance of keeping a high degree of suspicion for metastatic tumours in patients with a previous history of malignancy and the usefulness of CT scan in the evaluation of such cases...
  42. Gillespie M, Francis H, Chee N, Eisele D. Squamous cell carcinoma of the temporal bone: a radiographic-pathologic correlation. Arch Otolaryngol Head Neck Surg. 2001;127:803-7 pubmed
    ..To assess the utility of a previously proposed staging system for patients with primary squamous cell carcinoma of the temporal bone...
  43. Yeung P, Bridger A, Smee R, Baldwin M, Bridger G. Malignancies of the external auditory canal and temporal bone: a review. ANZ J Surg. 2002;72:114-20 pubmed
    ..Malignancies of the external auditory canal and temporal bone are uncommon. A retrospective review was conducted of a large series treated at the Prince of Wales hospital between 1974 and 1995...
  44. Reeck J, Yen T, Szmit A, Cheung S. Cavernous hemangioma of the external ear canal. Laryngoscope. 2002;112:1750-2 pubmed
    ..To document the occurrence of a cavernous hemangioma of the external ear canal and to review the relevant literature. STUDY DESIGN Case report and literature review...
  45. Kim Y, Chae S, Jung H. Mucoepidermoid carcinoma arising from the eustachian tube and middle ear. J Laryngol Otol. 2003;117:202-4 pubmed
    ..He received combined radiation therapy and chemotherapy and no residual or recurrent tumour was detected after two years of follow-up...
  46. Magliulo G, Parrotto D, Sardella B, Della Rocca C, Re M. Cavernous hemangioma of the tympanic membrane and external ear canal. Am J Otolaryngol. 2007;28:180-3 pubmed
    ..The aims of this study are to document the occurrence of a cavernous hemangioma of the tympanic membrane (TM) and external auditory canal (EAC) that invaded the middle ear spaces and to review the relevant literature...
  47. Di Lella F, Dispenza F, De Stefano A, Falcioni M, Sanna M. Management of intralabyrinthine schwannomas. Auris Nasus Larynx. 2007;34:459-63 pubmed
    ..Our protocol to manage the intralabyrinthine schwannoma (ILS)...
  48. Gross M, Maly A, Eliashar R, Attal P. Schwannoma of the external auditory canal. Auris Nasus Larynx. 2005;32:77-9 pubmed
    ..The clinical and histologic features, the differential diagnosis, and the treatment of external auditory canal schwannoma is discussed...
  49. Mueller C, Nicolaus K, Thorwarth M, Schultze Mosgau S. Multivariate analysis of the influence of patient-, tumor-, and management-related factors on the outcome of surgical therapy for facial basal-cell carcinoma. Oral Maxillofac Surg. 2010;14:163-8 pubmed publisher
    ..This retrospective, case-control study aimed at evaluating the influence of patient-, tumor-, and management-related factors on the outcome of surgical therapy for facial basal-cell carcinoma (BCC) employing a multivariate analysis...
  50. Kim H, Hagan M, Butman J, Baggenstos M, Brewer C, Zalewski C, et al. Surgical resection of endolymphatic sac tumors in von Hippel-Lindau disease: findings, results, and indications. Laryngoscope. 2013;123:477-83 pubmed publisher
    ..To define the surgical treatment and outcomes of von Hippel-Lindau (VHL) disease-associated endolymphatic sac tumors (ELSTs), we analyzed consecutive VHL patients who underwent ELST resection...
  51. Tysome J, Harcourt J, Patel M, Sandison A, Michaels L. Aggressive papillary tumor of the middle ear: a true entity or an endolymphatic sac neoplasm?. Ear Nose Throat J. 2008;87:378-93 pubmed
  52. Dingle I, Stachiw N, Bartlett A, Lambert P. Bilateral inverted papilloma of the middle ear with intracranial involvement and malignant transformation: first reported case. Laryngoscope. 2012;122:1615-9 pubmed publisher
  53. Smith B, Kempen P, Bouley D, Xu A, Liu Z, Melosh N, et al. Shape matters: intravital microscopy reveals surprising geometrical dependence for nanoparticles in tumor models of extravasation. Nano Lett. 2012;12:3369-77 pubmed publisher
    ..This work quantitatively indicates that nanoscale extravasational competence is highly dependent on nanoparticle geometry and is heterogeneous...