submandibular gland neoplasms

Summary

Summary: New abnormal growth of tissue in the SUBMANDIBULAR GLAND.

Top Publications

  1. Byeon H, Lim Y, Koo B, Choi E. Metastasis to the submandibular gland in oral cavity squamous cell carcinomas: pathologic analysis. Acta Otolaryngol. 2009;129:96-100 pubmed publisher
    ..Therefore, if the primary lesion of the oral cavity carcinoma is not in close proximity and hence does not provide suspicion of direct extension, it may be safe to preserve the submandibular gland...
  2. Razfar A, Walvekar R, Melkane A, Johnson J, Myers E. Incidence and patterns of regional metastasis in early oral squamous cell cancers: feasibility of submandibular gland preservation. Head Neck. 2009;31:1619-23 pubmed publisher
    ..We aimed to study the incidence of metastasis to the submandibular gland (SMG) and to establish the oncologic basis of SMG preservation in early-stage cancer of the oral cavity (OSCC)...
  3. Junquera L, Albertos J, Ascani G, Baladron J, Vicente J. [Involvement of the submadibular region in epidermoid carcinoma of the mouth floor. Prospective study of 31 cases]. Minerva Stomatol. 2000;49:521-5 pubmed
    ..To evaluate the primary or secondary involvement of the submandibular gland in floor of mouth squamous cell carcinoma...
  4. Spiegel J, Brys A, Bhakti A, Singer M. Metastasis to the submandibular gland in head and neck carcinomas. Head Neck. 2004;26:1064-8 pubmed
    ..The purpose of this retrospective chart review was to determine whether and how the submandibular gland is involved in metastases of squamous cell carcinoma of the head and neck...
  5. Terasaki M, Terasaki Y, Wakamatsu K, Takahashi M, Kunugi S, Urushiyama H, et al. A mucin-rich variant of salivary duct carcinoma with a prominent mucinous component, a tumor that mimics mucinous adenocarcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;116:e210-4 pubmed publisher
    ..mSDC with prominent mucinous component sometimes resembles mucinous adenocarcinoma. Identifying specific histological and immunohistochemical features of floating tumor nests in the mucinous area are important for the diagnosis...
  6. Tasaki T, Matsuyama A, Tabata T, Suzuki H, Yamada S, Sasaguri Y, et al. Sclerosing mucoepidermoid carcinoma with eosinophilia of the salivary gland: case report and review of the literature. Pathol Int. 2013;63:125-31 pubmed publisher
    ..Only 23 cases of sclerosing mucoepidermoid carcinoma with or without eosinophilic infiltratie have been reported to date in such an anatomical location...
  7. Kavusi S, Farahmand V, Davidson T, Farid N, Shabaik A. Osteolipoma presenting as a submandibular mass: a rare presentation. Head Neck Pathol. 2013;7:93-6 pubmed publisher
    ..Our review of head and neck osteolipomas would be of particular interest to pathologists and head and neck surgeons, in order to avoid inappropriate treatment of an otherwise benign lesion...
  8. Huq A, Aktaruzzaman M, Habib M, Islam M, Amin A. A comparative study between fine needle aspiration cytology findings and histopathological report of major salivary gland neoplasm in a tertiary hospital of Bangladesh. Bangladesh Med Res Counc Bull. 2013;39:69-73 pubmed
    ..3% and negative predictive 93.6% for FNAC.FNAC though cheap and safe but its diagnostic accuracy was 93.3%.Histopathologial examination remained to be of value for diagnostic confirmation of major salivary gland neoplasm...
  9. Subhashraj K. Salivary gland tumors: a single institution experience in India. Br J Oral Maxillofac Surg. 2008;46:635-8 pubmed publisher
    ..Demographic data from these studies should help us to a better understanding of the biological and clinical characteristics of the disease...

More Information

Publications62

  1. Fathallah L, Tulunay O, Feng J, Husain M, Jacobs J, Al Abbadi M. Histopathologic and cytopathologic diagnostic discrepancies in head and neck region: pitfalls, causes, and preventive strategies. Otolaryngol Head Neck Surg. 2006;134:302-8 pubmed
    ..Correlation of these results with the surgical resection diagnosis is an essential part of quality control and assurance programs in all cytology laboratories...
  2. Soares A, de Araújo V, Juliano P, Altemani A. Angiogenic and lymphangiogenic microvessel density in recurrent pleomorphic adenoma. J Oral Pathol Med. 2009;38:623-9 pubmed publisher
    ..In addition, immunohistochemical staining for the Ki-67 antigen was conducted simultaneously to evaluate cell proliferation in PA and RPA...
  3. Belli E, Marini Balestra F, Longo B. Giant pleomorphic adenoma of the submandibular gland. Case report. Minerva Stomatol. 2005;54:449-52 pubmed
    ..A complete surgical removal of the tumor is the treatment of choice. In the case presented, the mass showed an unusual vascularization and remarkable dimensions...
  4. Elloumi Jellouli A, Derbel F, Jellouli M, Ben Ammar S, Mrad K, Ben Romdhane K. Primary epidermoid carcinoma of the submandibular salivary gland. Dermatol Online J. 2005;11:26 pubmed
  5. Perera E, Revington P, Sheffield E. Low grade marginal zone B-cell lymphoma presenting as local amyloidosis in a submandibular salivary gland. Int J Oral Maxillofac Surg. 2010;39:1136-8 pubmed publisher
    ..This case demonstrates that a diagnosis of lymphoma must be considered when there is amyloidosis in an otherwise asymptomatic submandibular salivary gland mass...
  6. Ohashi T, Imokawa H, Kenmochi M, Sato S. Neck metastasis of a myxoid liposarcoma of the lower extremity. Auris Nasus Larynx. 2004;31:443-6 pubmed
    ..Where possible, therapy for liposarcomas should initially comprise complete and wide resection of the lesions. Combined therapy consisting of surgery and postoperative radiation and chemotherapy should be investigated in the future...
  7. Mariano F, da Silva S, Chulan T, de Almeida O, Kowalski L. Clinicopathological factors are predictors of distant metastasis from major salivary gland carcinomas. Int J Oral Maxillofac Surg. 2011;40:504-9 pubmed publisher
    ..These results provide evidences that clinicopathological factors (tumour site and histology) are significant predictors of distant metastasis in patients with major salivary gland carcinomas...
  8. Bahn Y, Lee S, Kwon S, Kim S. Sonographic appearances of mucosa-associated lymphoid tissue lymphoma of the submandibular gland confirmed with sonographically guided core needle biopsy. J Clin Ultrasound. 2011;39:228-32 pubmed publisher
    ..Sonographic features of MALT lymphoma of the submandibular gland are characteristic and ultrasound-guided core-needle biopsy may be a suitable replacement for surgical biopsy...
  9. Yu G, Donath K. Adenomatous ductal proliferation of the salivary gland. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;91:215-21 pubmed
    ..The objective of this study is to report a series of patients with adenomatous ductal proliferation of the salivary gland and to investigate the nature and histogenesis of this process...
  10. Moragas M, Soler M, Riera E, Garcia J. [Extension study and evaluation of the therapeutic response in a patient with metastatic lung adenocarcinoma using sequential study with ¹?F-FDG PET-CT and ¹?F-fluoride PET-CT]. Rev Esp Med Nucl Imagen Mol. 2015;34:45-8 pubmed publisher
    ..It also shows the usefulness of (18)F-fluoride PET-CT for monitoring the bone metastases. ..
  11. Pinkston J, Cole P. ABO blood groups and salivary gland tumors (Alabama, United States). Cancer Causes Control. 1996;7:572-4 pubmed
    ..The distribution of Rh factor among cases and controls also did not differ significantly (P = 0.08)...
  12. Syrigos K, Katirtzoglou N, Ntomi V, Pierrakou A, Chorti M, Stratakos G, et al. Pulmonary blastoma with submandibular, scrotum and adrenal metastases: case report. Respiration. 2012;83:83-6 pubmed publisher
    ..Treatment strategy in pulmonary blastoma should be defined by a multidisciplinary team, and surgical treatment should be considered as quickly as possible when such a tumor is suspected...
  13. Min R, Siyi L, Wenjun Y, Ow A, Lizheng W, Minjun D, et al. Salivary gland adenoid cystic carcinoma with cervical lymph node metastasis: a preliminary study of 62 cases. Int J Oral Maxillofac Surg. 2012;41:952-7 pubmed publisher
    ..Peritumoral lymphovascular invasion could be taken as strong predictor for lymph node metastasis, which ultimately leads to poor prognosis of ACC patient. Selective neck dissection should be considered in such cases...
  14. Agaimy A, Ihrler S, Märkl B, Lell M, Zenk J, Hartmann A, et al. Lipomatous salivary gland tumors: a series of 31 cases spanning their morphologic spectrum with emphasis on sialolipoma and oncocytic lipoadenoma. Am J Surg Pathol. 2013;37:128-37 pubmed publisher
    ..Oncocytic lipoadenoma is an epithelial-predominant tumor that is distinct from the fat-dominated nononcocytic sialolipoma, but the 2 types seem to merge in some cases...
  15. Pusiol T, Franceschetti I, Scialpi M, Piscioli I. Oncocytic sialolipoma of the submandibular gland with sebaceous differentiation: a new pathological entity. Indian J Pathol Microbiol. 2009;52:379-82 pubmed publisher
    ..The tumor was composed of mature adipose tissue surrounded by a thin fibrous capsule, multiple nodules of oncocytes, normal ductal-acinar units with focal ductal sebaceous differentiation...
  16. Nobis C, Rohleder N, Wolff K, Wagenpfeil S, Scherer E, Kesting M. Head and neck salivary gland carcinomas--elective neck dissection, yes or no?. J Oral Maxillofac Surg. 2014;72:205-10 pubmed publisher
    ..The authors evaluated their treatment by estimating the frequency of metastatic disease and identifying factors associated with an increased risk for metastatic disease...
  17. Rosti G, Callea A, Merendi R, Beccati D, Tienghi A, Turci D, et al. Metastases to the submaxillary gland from breast cancer: case report. Tumori. 1987;73:413-6 pubmed
    ..She then received six courses of CMF adjuvant program. A literature review is presented concerning the 8 well-documented cases reported...
  18. Abu A, Motoori K, Yamamoto S, Hanazawa T, Nagai Y, Kaneoya K, et al. MRI of chronic sclerosing sialoadenitis. Br J Radiol. 2008;81:531-6 pubmed publisher
    ..Although the intensities, ADC values and enhanced patterns of Kuttner's tumours were similar to those of malignant tumours, there were some morphological differences...
  19. Erkan A, Bal N, Caylakli F, Kiroglu F. [Epithelial-myoepithelial carcinoma of the submandibular gland: a case report]. Kulak Burun Bogaz Ihtis Derg. 2007;17:167-70 pubmed
    ..Left submandibular gland excision with functional neck dissection was performed. The histopathological diagnosis was epithelial-myoepithelial carcinoma of the submandibular gland with one lymph node metastasis...
  20. Cheng Y, Kessler H, Wright J, Huang E, Lin J, Lin L, et al. Salivary gland malignancy with divergent differentiation: is it a teratocarcinosarcoma?. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104:82-8 pubmed
    ..The pathological features and diagnoses of these malignant lesions are discussed...
  21. Guerrissi J, Taborda G. Endoscopic excision of the submandibular gland by an intraoral approach. J Craniofac Surg. 2001;12:299-303 pubmed
    ..With advanced endoscopic instruments, new surgical technique, and surgeon experience, endoscopic intraoral excision of the submandibular gland can be the method of choice in benign neoplasia, sialolith, sialoadenitis and plunging ranula...
  22. Fujisawa S, Atsumi T, Ishihara M, Kadoma Y. Cytotoxicity, ROS-generation activity and radical-scavenging activity of curcumin and related compounds. Anticancer Res. 2004;24:563-9 pubmed
    ..A molecular mechanism of cancer prevention by curcumin is proposed, based on its high reactivity with peroxy radicals at low oxygen pressure and on ROS generation induced by curcumin radicals...
  23. Armstrong J, Harrison L, Thaler H, Friedlander Klar H, Fass D, Zelefsky M, et al. The indications for elective treatment of the neck in cancer of the major salivary glands. Cancer. 1992;69:615-9 pubmed
    ..High-grade tumors and larger tumors have a high rate of occult neck metastases, and treatment should be considered in this group...
  24. Dai D. Postoperative irradiation in malignant tumors of submandibular gland. Cancer Invest. 1999;17:36-8 pubmed
    ..Such therapy can serve as the salvage method for those who have inadequate surgical margins. Re-excision is disappointing in its ability to control this disease...
  25. John S, Horo S, Braganza A, Kuriakose T. Bilateral choroidal metastasis from carcinoma of the submandibular gland. Indian J Ophthalmol. 2008;56:75-6 pubmed
    ..Metastatic tumor is the most common uveal malignancy. However, choroidal metastasis from a salivary gland neoplasm is extremely rare. We report a case of bilateral, multifocal choroidal metastasis from carcinoma of the submandibular gland...
  26. Kusafuka K, Watanabe H, Kimata K, Hiraki Y, Shukunami C, Kameya T. Minute pleomorphic adenoma of the submandibular gland in patients with oral malignancy: a report of two cases with histological and immunohistochemical examination. Histopathology. 2007;51:258-61 pubmed
  27. Becerril Ramírez P, Bravo Escobar G, Prado Calleros H, Castillo Ventura B, Pombo Nava A. [Histology of submandibular gland tumours, 10 years' experience]. Acta Otorrinolaringol Esp. 2011;62:432-5 pubmed publisher
    ..In the classical studies, the proportion of malignancy reported in these cases is around 50%...
  28. Zhong L, Zhao S, Chen G, Ping F. Ultrasonographic appearance of lipoma in the oral and maxillofacial region. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;98:738-40 pubmed
    ..To summarize the clinical situation, ultrasonographic appearance, diagnosis, and treatment experience of lipoma in the oral and maxillofacial region...
  29. Bhatia K, Rasalkar D, Lee Y, Wong K, King A, Yuen H, et al. Evaluation of real-time qualitative sonoelastography of focal lesions in the parotid and submandibular glands: applications and limitations. Eur Radiol. 2010;20:1958-64 pubmed publisher
    ..To evaluate qualitative ultrasound elastography for focal salivary gland masses identified during routine clinical practice...
  30. Tian Z, Li L, Wang L, Hu Y, Li J. Salivary gland neoplasms in oral and maxillofacial regions: a 23-year retrospective study of 6982 cases in an eastern Chinese population. Int J Oral Maxillofac Surg. 2010;39:235-42 pubmed publisher
    ..There was a high incidence of lymphoepithelial carcinomas but a low incidence of polymorphous low-grade adenocarcinoma. The historical significant male predominance of Warthin's tumor was confirmed...
  31. Varshavskiĭ A. [Mucoepidermoid carcinoma of parotid and submandibular glands: diagnostics and treatment]. Stomatologiia (Mosk). 2007;86:42-6 pubmed
    ..In conditions of thorough checkup and dispensary observation of the patients it was often possible to refrain from preventive interventions on neck lymphatic apparatus...
  32. Gao M, Hao Y, Huang M, Ma D, Luo H, Gao Y, et al. Clinicopathological study of distant metastases of salivary adenoid cystic carcinoma. Int J Oral Maxillofac Surg. 2013;42:923-8 pubmed publisher
    ..The biological characteristics of adenoid cystic carcinoma were different from those of squamous cell carcinoma. At present, the effectiveness of treatment for distant metastases is not ideal and further research is needed. ..
  33. Dyląg Trojanowska K. Giant submandibular gland tumor: mucoepidermoid carcinoma within the pleomorphic adenoma (mixed tumor). Pol Przegl Chir. 2011;83:227-30 pubmed publisher
    ..In spite of the good postoperative esthetic and functional effect the patient was diagnosed with distant metastases to the lungs...
  34. Chiang Y, Chen R, Chao P, Yang T, Lee F. Pediatric Kikuchi-Fujimoto disease masquerading as a submandibular gland tumor. Int J Pediatr Otorhinolaryngol. 2004;68:971-4 pubmed
    ..The case illustrates the clinical features of this unusual condition and emphasizes the potential confusion with other diagnoses...
  35. Aribandi M, Wood W, Elston D, Weiss D. CT features of plexiform neurofibroma of the submandibular gland. AJNR Am J Neuroradiol. 2006;27:126-8 pubmed
    ..A "branching" hypodense mass was noted on the CT scan infiltrating the submandibular gland and the adjacent spaces of the neck. CT could be extremely valuable in suggesting the diagnosis...
  36. Saito M, Nishiyama H, Maruyama S, Oda Y, Saku T, Hayashi T. Adenoid cystic carcinoma of sublingual gland involving the submandibular duct. Dentomaxillofac Radiol. 2008;37:421-4 pubmed publisher
    ..ACC of the sublingual gland extending into the submandibular duct is rare and the MR findings have not been previously described in the literature...
  37. Fu C, Ueng S, Shao P, Chang K. Pathology quiz case 1: solitary fibrous tumor (SFT) of the submandibular gland. Arch Otolaryngol Head Neck Surg. 2008;134:214, 216 pubmed publisher
  38. Parente P, Longobardi G, Bigotti G. Hamartomatous sialolipoma of the submandibular gland: case report. Br J Oral Maxillofac Surg. 2008;46:599-600 pubmed publisher
    ..The location of this tumour has not to our knowledge been previously described. The tumour was excised and has not recurred during 22 months postoperatively...
  39. Moatemri R, Belajouza H, Farroukh U, Ommezzine M, Slama A, Ayachi S, et al. [Epidemiological profile of salivary-glands tumors in a Tunisian teaching hospital]. Rev Stomatol Chir Maxillofac. 2008;109:148-52 pubmed publisher
    ..The aim of this retrospective study was to establish an epidemiological profile of salivary-glands tumors in a Tunisian teaching hospital and to compare it to published data...
  40. Gonçalves A, Menezes M, Kavabata N, Bertelli A, Souza R, Joelsons D. [Fine needle aspiration in salivary gland tumors: specificity and sensitivity]. Rev Assoc Med Bras (1992). 2007;53:267-71 pubmed
    ..As such, knowledge of correct cytological findings prior to surgery is important for therapeutic planning. This is not easily established since it is usually based only on the patients' clinical history and imaging exams..
  41. Chikui T, Tokumori K, Yoshiura K, Oobu K, Nakamura S, Nakamura K. Sonographic texture characterization of salivary gland tumors by fractal analyses. Ultrasound Med Biol. 2005;31:1297-304 pubmed
    ..The Hurst index obtained by the F BM model of pleomorphic adenoma was significantly lower than that of the malignant tumor...
  42. Munir N, Bradley P. Pleomorphic adenoma of the submandibular gland: an evolving change in practice following review of a personal case series. Eur Arch Otorhinolaryngol. 2007;264:1447-52 pubmed
  43. Ogawa Y, Wan F, Toyosawa S, Ijuhin N. Induction of adenocarcinoma containing myoepithelial cells in rat submandibular gland by 7,12-dimethylbenz(a)anthracene. Virchows Arch. 2000;437:314-24 pubmed
  44. Henze M, Hittel J. [Mucoepidermoid carcinoma of the salivary glands after high dosage radiotherapy]. Laryngorhinootologie. 2001;80:253-6 pubmed
    ..Due to active iodine accumulation, high focal radiation doses are received by the salivary glands...
  45. Babb M, Rasgon B, Cruz R, Rumore G. Submandibular gland squamous metaplasia mimicking recurrent squamous cell carcinoma: diagnostic dilemma. Arch Otolaryngol Head Neck Surg. 2002;128:1201-3 pubmed
    ..We review distinguishing clinical and histopathologic features that may allow these lesions to be identified. We also propose a treatment algorithm for this uncommon clinical scenario...
  46. Han M, Cho K, Roh J, Choi S, Nam S, Kim S. Patterns of lymph node metastasis and their influence on outcomes in patients with submandibular gland carcinoma. J Surg Oncol. 2012;106:475-80 pubmed publisher
    ..We therefore evaluated the metastatic topography of neck lymph nodes in patients with SMG carcinoma and the influence of metastases on tumor recurrence and patient survival...
  47. Kojima M, Nakamura S, Itoh H, Yamane Y, Shimizu K, Masawa N. Kuttner's tumor of salivary glands resembling marginal zone B-cell lymphoma of the MALT type: a histopathologic and immunohistochemical study of 7 cases. Int J Surg Pathol. 2004;12:389-93 pubmed
    ..However, immunohistological study demonstrated the mixed nature of the cells resembling centrocyte-like cells. Moreover, the polytypic nature of B lymphocytes was demonstrated by immunohistochemistry and polymerase chain reaction...
  48. Ascani G, Junquera L, Rodríguez Recio O, Gonzalez F. Asymptomatic submandibular mass. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95:529-32 pubmed
  49. Sun X, Xu J, Yang Q, Hu J, Wang Q. Lymphoepithelioma-like carcinoma of the submandibular salivary gland: a case report. Chin Med J (Engl). 2006;119:1315-7 pubmed
  50. Luksić I, Virag M, Manojlovic S, Macan D. Salivary gland tumours: 25 years of experience from a single institution in Croatia. J Craniomaxillofac Surg. 2012;40:e75-81 pubmed publisher
    ..The aim of this study was to determine the types, frequency, distribution, and demographic characteristics of salivary gland tumours in a large representative sample...
  51. Agale S, Momin Y, Agale V. Kuttner tumor: a report of an underdiagnosed entity. J Assoc Physicians India. 2010;58:694-5 pubmed
    ..KT is usually diagnosed by histopathologist when the lesion is surgically biopsied to confirm clinical diagnosis of malignancy...
  52. Al Sukhun J, Lindqvist C, Hietanen J, Leivo I, Penttila H. Central adenoid cystic carcinoma of the mandible: case report and literature review of 16 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:304-8 pubmed
  53. Hirokawa M, Shimizu M, Manabe T, Ito J, Ogawa S. Oncocytic lipoadenoma of the submandibular gland. Hum Pathol. 1998;29:410-2 pubmed
    ..We propose the diagnostic term "oncocytic lipoadenoma" for this benign tumor...