sublingual gland neoplasms

Summary

Summary: Neoplasms of the sublingual glands.

Top Publications

  1. Petersen S, Bjørndal K, Krogdahl A, Godballe C. [Basal cell adenocarcinoma of the sublingual gland]. Ugeskr Laeger. 2010;172:551-2 pubmed
    ..For example, a ranula, sialolithiasis and/or infection. Tumors of the sublingual gland are very rare, but 90% are malignant and therefore malignancy should always be excluded in case of an asymptomatic swelling covered by intact mucosa...
  2. Asaumi J, Shigehara H, Konouchi H, Yanagi Y, Hisatomi M, Matsuzaki H, et al. Assessment of carcinoma in the sublingual region based on magnetic resonance imaging. Oncol Rep. 2002;9:1283-7 pubmed
    ..In conclusion, the dynamic MRI may be useful in differentiating malignant from benign tumors, and in detecting the extent of the tumors in the sublingual carcinomas...
  3. Rinaldo A, Shaha A, Pellitteri P, Bradley P, Ferlito A. Management of malignant sublingual salivary gland tumors. Oral Oncol. 2004;40:2-5 pubmed
    ..Adjuvant radiotherapy should be considered in most of the patients after surgical excision...
  4. Andersen L, Therkildsen M, Ockelmann H, Bentzen J, Schiødt T, Hansen H. Malignant epithelial tumors in the minor salivary glands, the submandibular gland, and the sublingual gland. Prognostic factors and treatment results. Cancer. 1991;68:2431-7 pubmed
  5. Spiro R. Treating tumors of the sublingual glands, including a useful technique for repair of the floor of the mouth after resection. Am J Surg. 1995;170:457-60 pubmed
    ..From a 55-year experience with about 4,000 patients treated for salivary gland tumors, we have identified 18 patients (0.5%) who received definitive treatment for neoplasms arising in the sublingual glands...
  6. Ariyoshi Y, Shimahara M, Konda T, Tsuji M. Carcinoma ex pleomorphic adenoma of the sublingual gland: a case report. Int J Oral Sci. 2012;4:50-3 pubmed publisher
    ..Immunohistochemically, the cells that composed of cell rich sheets were positive to smooth muscle actin. Final diagnosis of myoepithelial carcinoma ex pleomorphic adenoma was made...
  7. Mahy P, Reychler H. [The pathology of salivary glands. Tumors of the salivary glands]. Rev Belge Med Dent (1984). 2006;61:141-53 pubmed
    ..Those malignant salivary glands tumors are rare and necessitate multidisciplinar staging and management in close collaboration with the pathologist and the radiation oncologist...
  8. Pinkston J, Cole P. ABO blood groups and salivary gland tumors (Alabama, United States). Cancer Causes Control. 1996;7:572-4 pubmed
    ..The distribution of Rh factor among cases and controls also did not differ significantly (P = 0.08)...
  9. Mariano F, da Silva S, Chulan T, de Almeida O, Kowalski L. Clinicopathological factors are predictors of distant metastasis from major salivary gland carcinomas. Int J Oral Maxillofac Surg. 2011;40:504-9 pubmed publisher
    ..These results provide evidences that clinicopathological factors (tumour site and histology) are significant predictors of distant metastasis in patients with major salivary gland carcinomas...

More Information

Publications62

  1. Morey Mas M, Caubet Biayna J, Gomez Bellvert C, Iriarte Ortabe J. Carcinosarcoma of the submandibular and sublingual salivary glands. A case report and review of the literature. Acta Stomatol Belg. 1997;94:69-73 pubmed
    ..To our knowledge, we have not found any previously reported carcinosarcoma involving the sublingual gland...
  2. Papadogeorgakis N, Kalfarentzos E, Vourlakou C, Malta F, Exarhos D. Simultaneous pleomorphic adenoma of the left parotid gland and adenoid cystic carcinoma of the contralateral sublingual salivary gland: a case report. Oral Maxillofac Surg. 2009;13:221-4 pubmed publisher
    ..The coexistence of two salivary gland tumors located in different major salivary glands is uncommon...
  3. Zdanowski R, Dias F, Barbosa M, Lima R, Faria P, Loyola A, et al. Sublingual gland tumors: clinical, pathologic, and therapeutic analysis of 13 patients treated in a single institution. Head Neck. 2011;33:476-81 pubmed publisher
    ..Sublingual gland tumors are rare, although frequently malignant. This study describes the clinicopathologic features and treatment results and reviews the literature...
  4. Okada H, Tanaka S, Tajima H, Akimoto Y, Kaneda T, Yamamoto H. Schwannoma arising from the sublingual gland. Ann Diagn Pathol. 2012;16:141-4 pubmed publisher
    ..58. The clear presence of a remnant sublingual gland lobule in the present tumor provided convincing evidence that it was a schwannoma arising from the sublingual gland and thus the first of its type to be reported...
  5. Gooris P, Worthington P, Evans J. Mandibulotomy: a surgical approach to oral and pharyngeal lesions. Int J Oral Maxillofac Surg. 1989;18:359-64 pubmed
    ..It is concluded that mandibulotomy has a place in the management of malignancies as well as awkwardly situated benign lesions as well as malignancies...
  6. Tanaka N, Hsieh K, Kino K, Amagasa T, Shioda S, Miyamoto H, et al. A case report of papillary adenocarcinoma in sublingual region--ultrastructural and histochemical study. Bull Tokyo Med Dent Univ. 1989;36:41-8 pubmed
    ..However, the final histopathologic diagnosis was papillary adenocarcinoma. We investigated its origin by histological, ultrastructural and histochemical techniques and it was suggested that this tumor arose from the minor salivary gland...
  7. Rutt A, Hawkshaw M, Lurie D, Sataloff R. Salivary gland cancer in patients younger than 30 years. Ear Nose Throat J. 2011;90:174-84 pubmed
    ..We found that SGC affects patients of all ages, even children in the first year of life. It is essential for physicians to detect salivary gland neoplasms promptly and to evaluate them thoroughly when they are found in children...
  8. Teshima T, Inoue T, Ikeda H, Yamazaki H, Ohtani M, Shimizutani K, et al. Radiation therapy for carcinoma of the major salivary glands. Results of conventional irradiation technique. Strahlenther Onkol. 1993;169:486-91 pubmed
    ..However, the local control rates for the radiation only group were only 30 to 40%, so that new irradiation modalities such as provided by a high LET machine are needed for these patients...
  9. Esposito E, Cassiano B, Cinquegrani F. Salivary glands: report of a rare case of myoepithelial carcinoma involving tongue base treated by CO2 Laser. Acta Otorhinolaryngol Ital. 2009;29:156-9 pubmed
    ..In this report, the possibility of applying conservative surgery using CO(2) Laser is proposed. Results obtained in the case described confirm that conservative surgery is feasible in this type of neoplastic lesion of the tongue...
  10. Walvekar R, Peters G, Hardy E, Alsfeld L, Stromeyer F, Anderson D, et al. Robotic-assisted transoral removal of a bilateral floor of mouth ranulas. World J Surg Oncol. 2011;9:78 pubmed publisher
    ..To describe the management of bilateral oral ranulas with the use of the da Vinci Si Surgical System and discuss advantages and disadvantages over traditional transoral resection...
  11. Sugano S, Mukai K, Tsuda H, Hirohashi S, Furuya S, Shimosato Y, et al. Immunohistochemical study of c-erbB-2 oncoprotein overexpression in human major salivary gland carcinoma: an indicator of aggressiveness. Laryngoscope. 1992;102:923-7 pubmed
    ..05). We conclude that immunohistochemical positivity for c-erbB-2 is an indicator of aggressiveness in both adenocarcinoma and adenocarcinoma in pleomorphic adenoma of the major salivary glands...
  12. Guo Q, Xue J, Xu L, Shi Z, Zhou B. The clinical features of epithelioid hemangioendothelioma in a Han Chinese population: A retrospective analysis. Medicine (Baltimore). 2017;96:e7345 pubmed publisher
    ..EHE is a very rare in Shaanxi. It is significant to find its clinical, radiological, and pathological characters, helping for EHE early diagnosis and treatment, reducing misdiagnosis and improving life quality...
  13. Gillenwater A, Frank S, Fatani H, El Naggar A. Primary intestinal-like adenocarcinoma of major salivary glands: 2 instances of previously undocumented phenotype. Head Neck. 2013;35:E234-6 pubmed publisher
    ..Primary intestinal-like adenocarcinoma of the major salivary glands has not previously been reported...
  14. Hiranuma T, Kagamiuchi H, Kitamura R. A basal cell adenoma of the sublingual gland. Int J Oral Maxillofac Surg. 2003;32:566-7 pubmed
    ..To the knowledge of the authors, only one case of a basal cell adenoma of the sublingual gland has ever been reported. We report a second case of a basal cell adenoma arising from the sublingual gland in this paper...
  15. Tagawa S, Inui M, Mori A, Seki Y, Murata T, Tagawa T. Adenomatoid serous hyperplasia of sublingual gland: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996;82:437-40 pubmed
    ..We cannot identify the cause of this condition, however, calcium channel blocking agents prescribed for the treatment of this patient's essential hypertension cannot be ruled out as a pathogenetic factor in the development of the lesion...
  16. Nichols C, Geist R, Nichols K. Clear cell neoplasm. J Laryngol Otol. 1992;106:553-5 pubmed
    ..It is hoped that ours and similar reports will be helpful towards clearing the diagnostic and taxonomic confusion regarding these tumours...
  17. Whear N, Addy J. Adenoid cystic carcinoma of the sublingual gland--an unusual presentation. Br J Oral Maxillofac Surg. 1993;31:113-6 pubmed
    ..A review of the literature suggests that this is the first such case to be reported. The importance of intra-oral examination when investigating swellings of the neck is emphasised...
  18. Ostman J, Anneroth G, Gustafsson H, Tavelin B. Malignant salivary gland tumours in Sweden 1960-1989--an epidemiological study. Oral Oncol. 1997;33:169-76 pubmed
  19. Dongre A, Khopkar U. Asymptomatic nodule on lip. Indian J Dermatol Venereol Leprol. 2006;72:470 pubmed
  20. Aninos D, Koumarianou A, Georgoulakis J, Pektasidis D, Brountzos E, Zoumpouli C, et al. Liver metastasis of adenoid cystic carcinoma of salivary origin: report of a case prepared by ThinPrep method. Cytopathology. 2007;18:268-9 pubmed
  21. Wen S, Mizugaki Y, Shinozaki F, Takada K. Epstein-Barr virus (EBV) infection in salivary gland tumors: lytic EBV infection in nonmalignant epithelial cells surrounded by EBV-positive T-lymphoma cells. Virology. 1997;227:484-7 pubmed
    ..These results indicate that there is an unusual association of salivary gland T-cell lymphomas with lytic EBV replication of nonmalignant epithelial cells...
  22. Matsuzaka K, Shibahara T, Murakami S, Lee D, Shimono M, Inoue T. Acinic cell carcinoma found by recurrence of a mucous cyst in the sublingual gland. Bull Tokyo Dent Coll. 2004;45:95-8 pubmed
    ..This report concludes that the pathological diagnosis is beneficial in clarifying the reasons for the recurrence of a benign lesion...
  23. Clark J, Bailey B, Eveson J. Dysplastic pleomorphic adenoma of the sublingual salivary gland. Br J Oral Maxillofac Surg. 1993;31:394-5 pubmed
    ..The tumour showed areas of dysplasia and the difficulties in distinguishing this from benign pleomorphic adenoma or carcinoma in pleomorphic adenoma are considered, and the literature is reviewed...
  24. Kornfehl J, Fichtenbauer H, Steiner E, Regele H, Strohmayer W. [Primary squamous epithelial cancer of the sublingual gland. A case report]. HNO. 1994;42:362-5 pubmed
    ..During a 3-year follow up period the patient was still tumor-free. We suggest--in concurrence with the literature--the use of this combined therapy in cases of malignant neoplasms of the minor salivary glands...
  25. Gunhan O, Yildiz F, Celasun B, Onder T, Finci R. Solitary fibrous tumour arising from sublingual gland: report of a case. J Laryngol Otol. 1994;108:998-1000 pubmed
    ..A solitary fibrous tumour is a pleural tumour which may rarely be detected at non-pleural sites. In this report, the case of a solitary fibrous tumour arising from the sublingual salivary gland is described...
  26. Pinkston J, Cole P. Incidence rates of salivary gland tumors: results from a population-based study. Otolaryngol Head Neck Surg. 1999;120:834-40 pubmed
    ..05). Warthin's tumor was rare in black patients (P < 0.001). We conclude that salivary gland tumors are an uncommon but epidemiologically diverse group of tumors. Their causes are also likely to differ...
  27. Carreto Sánchez J, Guerrero Alonso C, Balderrama Caballero D, Relea Calatayud F, Ortega de la Obra P. [Adenoid cystic carcinoma. Presentation of three clinical cases]. Acta Otorrinolaringol Esp. 1999;50:336-40 pubmed
    ..The literature is reviewed for information about the fundamental clinical, diagnostic, and therapeutic aspects of these tumors...
  28. Dawood A, Tanner S, Hutchison I. Computer guided surgery for implant placement and dental rehabilitation in a patient undergoing sub-total mandibulectomy and microvascular free flap reconstruction. J Oral Implantol. 2013;39:497-502 pubmed publisher
    ..The patient's personal assessment 2 years post surgery was recorded using 1999 University of Washington Quality of Life Questionnaire. ..
  29. Bradley P, McGurk M. Incidence of salivary gland neoplasms in a defined UK population. Br J Oral Maxillofac Surg. 2013;51:399-403 pubmed publisher
    ..However, this points towards a lower incidence of cancer in the major salivary glands than was traditionally thought...
  30. Bai S, Sun C. Tuberculous osteomyelitis of the mandible with diffuse swelling of the floor of the mouth: a case report. J Oral Maxillofac Surg. 2014;72:749.e1-6 pubmed publisher
    ..The purpose of the present study was to alert clinicians to our findings and encourage them to consider oral TB in the differential diagnosis for jaw lesions with multiple enlarged cervical lymph nodes...
  31. Lingam R, Daghir A, Nigar E, Abbas S, Kumar M. Pleomorphic adenoma (benign mixed tumour) of the salivary glands: its diverse clinical, radiological, and histopathological presentation. Br J Oral Maxillofac Surg. 2011;49:14-20 pubmed publisher
    ..The choice of imaging is influenced by its site and size, and a range of options for treatment includes both operation and radiotherapy. The tumour can also present in various ways if it is not removed or treated successfully...
  32. Danford M, Eveson J, Flood T. Papillary cystadenocarcinoma of the sublingual gland presenting as a ranula. Br J Oral Maxillofac Surg. 1992;30:270-2 pubmed
    ..A case is reported of a papillary cystadenocarcinoma of the sublingual gland which presented as a ranula. This is both rare in site and mode of presentation...
  33. Nagao T, Sugano I, Matsuzaki O, Hara H, Kondo Y, Nagao K. Intraductal papillary tumors of the major salivary glands: case reports of benign and malignant variants. Arch Pathol Lab Med. 2000;124:291-5 pubmed
    ..The malignant counterpart of intraductal papilloma should be considered in the differential diagnosis of salivary gland tumors with a predominantly papillary structure, even though this tumor is extremely rare...
  34. Matsuzaka K, Murakami S, Shimono M, Kakizawa T, Inoue T. Oncocytic tumor in myoepithelioma arising from the grossopalatine gland. Oral Oncol. 2003;39:306-8 pubmed
    ..The oncocytic tumor contained large amounts of eosinophilic granular cytoplasm and small nuclei...
  35. Ogawa Y, Kishino M, Nakazawa M, Iwai S, Ohta Y, Ishida T, et al. Adenoid cystic carcinoma associated with salivary duct cyst in the sublingual gland. J Oral Pathol Med. 2004;33:311-3 pubmed
    ..Therefore, our case has presented for the first time a direct evidence that adenoid cystic carcinoma arises from acinus/intercalated duct...
  36. Perez D, Pires F, Alves F, Almeida O, Kowalski L. Sublingual salivary gland tumors: clinicopathologic study of six cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100:449-53 pubmed
    ..The aim of this study was to assess the clinical and histologic features of 6 cases of sublingual salivary gland tumors treated in a single institution...
  37. Kumar P, Sobhani S, Monabati A, Hashemi S, Eghtadari F, Hamidi S. Myoepithelioma of the salivary glands. Fine needle aspiration biopsy findings. Acta Cytol. 2004;48:302-8 pubmed
    ..To evaluate the cytologic findings and pitfalls in the diagnosis of myoepithelioma of the salivary glands...
  38. Krogdahl A, Schou C. Mucinous adenocarcinoma of the sublingual gland. J Oral Pathol Med. 1997;26:198-200 pubmed
    ..Staining for estrogen and progesterone receptors was negative. No other cancer has been detected for three years after the first examination. The tumor is considered to be a primary mucinous adenocarcinoma of the sublingual gland...
  39. Lütje S, Sauerwein W, Lauenstein T, Bockisch A, Poeppel T. In Vivo Visualization of Prostate-Specific Membrane Antigen in Adenoid Cystic Carcinoma of the Salivary Gland. Clin Nucl Med. 2016;41:476-7 pubmed publisher
    ..Potentially, Ga-PSMA PET might be used for noninvasive assessment of adenoid cystic carcinoma to evaluate whether patients apply for PSMA-based radiotherapy when no further treatment options are available. ..
  40. Hamper K, Brugmann M, Caselitz J, Arps H, Berger J, Askensten U, et al. Prognosis of salivary adenocarcinomas. A retrospective study of 52 cases with special regard to cytochemically assessed nuclear DNA content. Virchows Arch A Pathol Anat Histopathol. 1989;416:57-64 pubmed
    ..28 cases were diploid, 9 were atypical. The clinical course was significantly related to the histogram type, atypical tumours showing a dismal prognosis...
  41. Honda K, Kusama H, Takagi S, Sekine S, Noguchi M, Chiba H. Diagnosis of intra-oral MALT lymphoma using seminested polymerase chain reaction. Br J Oral Maxillofac Surg. 2004;42:28-32 pubmed
    ..The molecular method described can be applied routinely to processed specimens to obtain helpful information for the diagnosis of low-grade malignancies of lymphoproliferative disorders, such as MALT lymphoma...
  42. Clark J, Franklin J, Naranjo N, Odell M, Gullane P. Sublingual gland resection in squamous cell carcinoma of the floor of mouth: is it necessary?. Laryngoscope. 2006;116:382-6 pubmed
    ..This study aims to determine the frequency with which the SLG is invaded, to identify variables predicting for SLG invasion and the morbidity associated with it's resection in entirety...
  43. Yu T, Gao Q, Wang X, Wen Y, Li L. Malignant sublingual gland tumors: a retrospective clinicopathologic study of 28 cases. Oncology. 2007;72:39-44 pubmed
    ..To evaluate the clinicopathologic features and therapeutic efficacy of malignant sublingual gland tumors...
  44. Bogsrud T, Karantanis D, Lowe V. Normal uptake of F-18 FDG in the sublingual gland. Clin Nucl Med. 2006;31:50 pubmed
  45. Arda H, Akdogan O, Arda N, Sarikaya Y. An unusual site for an intraoral schwannoma: A case report. Am J Otolaryngol. 2003;24:348-50 pubmed
    ..We presented a schwannoma arising from the parasympathetic fibers of the lingual nerve, which is the first in the literature to our knowledge. Its borders in computerized tomography are not well defined despite the contrast medium...
  46. Blanchaert R, Ord R, Kumar D. Polymorphous low-grade adenocarcinoma of the sublingual gland. Int J Oral Maxillofac Surg. 1998;27:115-7 pubmed
    ..This is the first case ever reported of this entity occurring in the sublingual gland. This paper brings into question the early belief that this tumor is restricted to intraoral minor salivary glands...
  47. Ota Y, Arai I, Aoki T, Yamazaki H, Karakida K, Tsukinoki K. Acinic cell carcinoma of the sublingual gland accompanied by bone formation. Tokai J Exp Clin Med. 2001;26:127-30 pubmed
    ..Based on these findings, the tumor was diagnosed as acinic cell carcinoma accompanied by bone formation. Postoperative recovery was uneventful, and two years after surgery, there are no signs of distant metastases or recurrence...
  48. Shimoyama Y, Yamashita K, Ohmachi T, Akihara Y, Sako T, Hirayama K, et al. Pleomorphic adenoma of the salivary gland in two dogs. J Comp Pathol. 2006;134:254-9 pubmed
    ..Labelling for GFAP indicated stromal transformation into myxoid and chondroid tissues...
  49. Maruya S, Namba A, Matsubara A, Kakehata S, Takeda I, Shirasaki T, et al. Salivary gland carcinoma treated with concomitant chemoradiation with intraarterial cisplatin and docetaxel. Int J Clin Oncol. 2006;11:403-6 pubmed
    ..The concomitant chemoradiotherapy of cisplatin and docetaxel seemed to be a practicable option for patients with recurrent and unresectable salivary gland carcinomas...
  50. López Quiles J, Ferreira E, Jimenez Heffernan J, del Canto M. Clear cell carcinoma of the major salivary glands in an HIV-infected patient. Int J Oral Maxillofac Surg. 2011;40:760-3 pubmed publisher
    ..To date, this association has not been described in the medical literature. The low grade of malignancy reported for this tumour demands a precise diagnosis and complete tumoral excision...
  51. Goode R, Auclair P, Ellis G. Mucoepidermoid carcinoma of the major salivary glands: clinical and histopathologic analysis of 234 cases with evaluation of grading criteria. Cancer. 1998;82:1217-24 pubmed
    ..The current study investigated the usefulness of these features in determining the prognoses of patients with mucoepidermoid carcinomas of the major salivary glands...
  52. Law N, Leader M. Bilateral submandibular gland lymphoma in Sjögren's syndrome. Postgrad Med J. 1987;63:135-6 pubmed
    ..A lymphoma involving more than one salivary gland may occur in Sjögren's syndrome, and there is an increased risk of developing an extrasalivary lymphoma...
  53. Kwon Y, Biesterfeld S, Hansen T, Schwerdtfeger A, Kunkel M. Lymphadenomatous carcinoma of the sublingual gland: report of a first case in an unusual localization. Head Neck. 2008;30:1394-8 pubmed publisher
    ..This report describes a case of lymphadenomatous carcinoma of the sublingual gland, which is thought to be the first report of this special entity...