facial neoplasms

Summary

Summary: New abnormal growth of tissue in the FACE.

Top Publications

  1. Miller W, Hayes V, Ratan A, Petersen D, Wittekindt N, Miller J, et al. Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil). Proc Natl Acad Sci U S A. 2011;108:12348-53 pubmed publisher
    ..Using a genetically characterized breeding stock based on the genome sequence will enable preservation of the extant genetic diversity in future Tasmanian devil populations...
  2. Wataya Kaneda M, Tanaka M, Nakamura A, Matsumoto S, Katayama I. A topical combination of rapamycin and tacrolimus for the treatment of angiofibroma due to tuberous sclerosis complex (TSC): a pilot study of nine Japanese patients with TSC of different disease severity. Br J Dermatol. 2011;165:912-6 pubmed publisher
    ..Although rapamycin improves many TSC lesions, significant side-effects appear after systemic administration. Topical administration has been recommended...
  3. Foster R, Bint L, Halbert A. Topical 0.1% rapamycin for angiofibromas in paediatric patients with tuberous sclerosis: a pilot study of four patients. Australas J Dermatol. 2012;53:52-6 pubmed publisher
    ..Although larger studies are needed, this treatment shows a potential to be a first-line management for facial angiofibromas in TSC and appears safe to start in early childhood...
  4. Murchison E, Schulz Trieglaff O, Ning Z, Alexandrov L, Bauer M, Fu B, et al. Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer. Cell. 2012;148:780-91 pubmed publisher
  5. Truchuelo T, Díaz Ley B, Rios L, Alcántara J, Jaen P. Facial angiofibromas treated with topical rapamycin: an excellent choice with fast response. Dermatol Online J. 2012;18:15 pubmed
    ..We report the 6th case of facial AF treated with topical rapamycin, 1 percent, once per day. An excellent response was achieved surprisingly rapidly. We propose this option as a safe and effective therapy...
  6. Kaufman McNamara E, Curtis A, Fleischer A. Successful treatment of angiofibromata of tuberous sclerosis complex with rapamycin. J Dermatolog Treat. 2012;23:46-8 pubmed publisher
    ..Our patients demonstrated decreased numbers of angiofibromata and less redness with this treatment. This is the first published report on the use of topical rapamycin for the treatment of angiofibromata...
  7. Lachish S, Miller K, Storfer A, Goldizen A, Jones M. Evidence that disease-induced population decline changes genetic structure and alters dispersal patterns in the Tasmanian devil. Heredity (Edinb). 2011;106:172-82 pubmed publisher
    ..Ongoing management of Tasmanian devils must now attempt to maintain genetic variability in this species through actions designed to reverse the detrimental effects of inbreeding and subdivision in disease-affected populations...
  8. McCallum H, Jones M, Hawkins C, Hamede R, Lachish S, Sinn D, et al. Transmission dynamics of Tasmanian devil facial tumor disease may lead to disease-induced extinction. Ecology. 2009;90:3379-92 pubmed
  9. Murchison E, Tovar C, Hsu A, Bender H, Kheradpour P, Rebbeck C, et al. The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer. Science. 2010;327:84-7 pubmed publisher
    ..We provide a genomic data set for the Tasmanian devil that is applicable to cancer diagnosis, disease evolution, and conservation biology...

More Information

Publications62

  1. Dogra S, Kumaran M, Radotra B, Kanwar A. Segmental neurofibromatosis on the face. Clin Exp Dermatol. 2004;29:556-8 pubmed
  2. Al Khateeb T, Al Hadi Hamasha A, Almasri N. Oral and maxillofacial tumours in north Jordanian children and adolescents: a retrospective analysis over 10 years. Int J Oral Maxillofac Surg. 2003;32:78-83 pubmed
    ..The majority of benign tumours in the young are probably developmental rather than true neoplasms...
  3. Kurabayashi T, Ida M, Tetsumura A, Ohbayashi N, Yasumoto M, Sasaki T. MR imaging of benign and malignant lesions in the buccal space. Dentomaxillofac Radiol. 2002;31:344-9 pubmed
    ..To evaluate MRI characteristics of buccal space lesions and to discuss the sensitivity of MRI in predicting malignancy of those lesions...
  4. Lachish S, Jones M, McCallum H. The impact of disease on the survival and population growth rate of the Tasmanian devil. J Anim Ecol. 2007;76:926-36 pubmed
    ..5. The arrival of DFTD coincided with a marked, ongoing decline in the population growth rate of the previously stable population, which to date has not been offset by population compensatory responses...
  5. Loh R, Bergfeld J, Hayes D, O Hara A, Pyecroft S, Raidal S, et al. The pathology of devil facial tumor disease (DFTD) in Tasmanian Devils (Sarcophilus harrisii). Vet Pathol. 2006;43:890-5 pubmed
    ..There was minimal cytologic differentiation among the tumor cell population under light and electron microscopic examination. The results indicate DFTD to be an undifferentiated soft tissue neoplasm...
  6. Dingli D, Nowak M. Cancer biology: infectious tumour cells. Nature. 2006;443:35-6 pubmed
  7. Pearse A, Swift K. Allograft theory: transmission of devil facial-tumour disease. Nature. 2006;439:549 pubmed
  8. Smeets N, Kuijpers D, Nelemans P, Ostertag J, Verhaegh M, Krekels G, et al. Mohs' micrographic surgery for treatment of basal cell carcinoma of the face--results of a retrospective study and review of the literature. Br J Dermatol. 2004;151:141-7 pubmed
    ..Mohs' micrographic surgery (MMS) is an advanced excision technique which is often used to treat BCC in the U.S.A. In Europe it is practised less frequently...
  9. McCallum H. Tasmanian devil facial tumour disease: lessons for conservation biology. Trends Ecol Evol. 2008;23:631-7 pubmed publisher
  10. Mosterd K, Krekels G, Nieman F, Ostertag J, Essers B, Dirksen C, et al. Surgical excision versus Mohs' micrographic surgery for primary and recurrent basal-cell carcinoma of the face: a prospective randomised controlled trial with 5-years' follow-up. Lancet Oncol. 2008;9:1149-56 pubmed publisher
    ..We did a prospective randomised controlled trial to compare the effectiveness of surgical excision with Mohs' micrographic surgery (MMS) for the treatment of primary and recurrent facial BCC...
  11. Loh R, Hayes D, Mahjoor A, O Hara A, Pyecroft S, Raidal S. The immunohistochemical characterization of devil facial tumor disease (DFTD) in the Tasmanian Devil (Sarcophilus harrisii). Vet Pathol. 2006;43:896-903 pubmed
    ..These staining characteristics are consistent with cells of neuroectodermal origin...
  12. Hori K, Soejima K, Nozaki M, Sakurai H, Takeuchi M, Yamaki T, et al. Treatment of facial angiofibroma of tuberous sclerosis using cultured epithelial autografts. Ann Plast Surg. 2006;57:415-7 pubmed
    ..In some patients, some pebbly regrowth had occurred at 5 years postoperatively, but the appearance was quite acceptable...
  13. Agarwal A, Thappa D, Jayanthi S, Shivaswamy K. Segmental neurofibromatosis of face. Dermatol Online J. 2005;11:33 pubmed
    ..These features were consistent with our clinical diagnosis of segmental neurofibromatosis. This case is reported for its rarity and typical manifestations...
  14. El Musa K, Shehadi R, Shehadi S. Extensive facial adenoma sebaceum: successful treatment with mechanical dermabrasion: case report. Br J Plast Surg. 2005;58:1143-7 pubmed
    ..This report documents the successful elimination of disfiguring sebaceous adenomas from the face of a 21-year-old male patient with mechanical dermabrasion...
  15. Liu J, Ma Y, Ma X, Chen J, Sun Y, Xu H, et al. A retrospective study of q-switched alexandrite laser in treating nevus of ota. Dermatol Surg. 2011;37:1480-5 pubmed publisher
    ..The Q-switched alexandrite laser (QSAL) has been clinically proven to be effective in treating nevus of Ota, but a large-scale retrospective study with long-term follow-up has never been performed...
  16. Duarte I. Multiple injuries of osteoma skin in the face: therapeutical least invasive in patients with acne sequela - case report. An Bras Dermatol. 2010;85:695-8 pubmed
    ..To remove the osteoma we used needle BD 0,70x25 22G1, without anesthetic topic or inject able site. The small wounds were exposed with scarring balsam. We got an excellent esthetic result after 15 days...
  17. Schwipper V. Invasive basal cell carcinoma of the head and neck (basalioma terebrans). Facial Plast Surg. 2011;27:258-65 pubmed publisher
    ..Although definite healing seems impossible, surgery may contribute to an acceptable quality of life for several years...
  18. Suh K, Rosbe K, Meyer A, Frieden I. Extensive airway hemangiomas in two patients without beard hemangiomas. Pediatr Dermatol. 2011;28:347-8 pubmed publisher
  19. Cheng H, Wu C, Tseng C, Chen H, Lee W, Chen P, et al. The occlusion-adjusted prefabricated 3D mirror image templates by computer simulation: the image-guided navigation system application in difficult cases of head and neck reconstruction. Ann Plast Surg. 2009;63:517-21 pubmed publisher
    ..The computer-simulated occlusion-adjusted 3D mirror image templates aid in the use of free vascularized bone flaps for restoring continuity to the mandible. The coordinated arch will help with further osseointegration teeth insertion...
  20. Zapater E, Bagan J, Carbonell F, Basterra J. Malignant lymphoma of the head and neck. Oral Dis. 2010;16:119-28 pubmed publisher
    ..Finally, the different therapeutic approaches are discussed...
  21. Leaute Labreze C, Sans Martin V. [Infantile hemangioma]. Presse Med. 2010;39:499-510 pubmed publisher
    ..The usual choice for second-line treatment is interferon or vincristine. The efficacy of propranolol, a non-cardioselective beta-blocker, was recently reported...
  22. Phung T, Hochman M. Pathogenesis of infantile hemangioma. Facial Plast Surg. 2012;28:554-62 pubmed publisher
    ..In this article, we present a comprehensive review of the current knowledge of the pathogenesis of hemangioma as well as promising research horizons and implications for new therapeutic advances...
  23. Beogo R, Andonaba J, Bouletreau P, Traore Sawadogo H, Traore A. [Multiple facial squamous cell carcinomas in a child, revealing a xeroderma pigmentosum]. Rev Stomatol Chir Maxillofac. 2012;113:50-2 pubmed publisher
    ..One of its most common risk factors is xeroderma pigmentosum (XP), an autosomal recessive disease characterized by defective cellular DNA repair, and hypersensitivity to ultraviolet radiation...
  24. O Neill T, Rawlins J, Rea S, Wood F. Treatment of a large congenital melanocytic nevus with dermabrasion and autologous cell suspension (ReCELL®): a case report. J Plast Reconstr Aesthet Surg. 2011;64:1672-6 pubmed publisher
    ..Dressings were no longer required by the 8th post-operative day, and excellent skin pigmentation and texture was achieved by 5 months post-op...
  25. Lopez M, Vermersch S, Varlet F. Endoscopic Excision of Forehead and Eyebrow Benign Tumors in Children. J Laparoendosc Adv Surg Tech A. 2016;26:226-30 pubmed publisher
    ..This study evaluates the efficacy of the endoscopic approach in the treatment of dermoid cysts of the eyebrow and defines the place of this approach as an alternative to open surgery...
  26. Luo Q, Zhao F. How to use bleomycin A5 for infantile maxillofacial haemangiomas: clinical evaluation of 82 consecutive cases. J Craniomaxillofac Surg. 2011;39:482-6 pubmed publisher
    ..We have used bleomycin A5 to treat maxillofacial IHs for 15 years. This paper describes the procedures to use bleomycin A5 and avoid its complications based on our clinical practices...
  27. Kuehnemund M, Bootz F. Reconstruction of the cheek. Facial Plast Surg. 2011;27:284-9 pubmed publisher
    ..Considering these conditions, various approaches in cheek reconstruction are discussed in this article...
  28. Rathore D, Mohyudin M, Mehta P, Ahluwalia H. Atypical fibroxanthoma of the medial canthus: a rare presentation. Orbit. 2013;32:194-6 pubmed publisher
    ..Atypical fibroxanthoma (AFX) is an uncommon skin tumour occurring primarily in the head and neck. It has rarely been reported in the periocular region. We report a rare case of atypical fibroxanthoma of the medial canthus...
  29. Mina M, Picariello A, Fewkes J. Superficial basal cell carcinomas of the head and neck. Dermatol Surg. 2013;39:1003-8 pubmed publisher
    ..Superficial basal cell carcinomas (BCC) are often considered a non-aggressive form of skin cancer, most often found on the trunk in younger patients...
  30. Moutran R, Maatouk I, Stephan F, Tomb R. Treatment of nodular basal cell carcinoma with cryotherapy and reduced protocol of imiquimod. Cutis. 2012;90:256-7 pubmed
    ..Clearance of the lesion was histologically confirmed...
  31. Keeley T, McGreevy P, O Brien J. The effects of season and devil facial tumour disease on the reproductive physiology of the male Tasmanian devil (Sarcophilus harrisii). Reprod Fertil Dev. 2012;24:999-1007 pubmed publisher
    ..05), nor influenced by disease stage (P>0.1). Seasonal and DFTD-related changes in serum cortisol concentrations were not evident (P>0.1). Male devil reproduction does not appear to be restricted by season nor inhibited by DFTD...
  32. Kluger N, Letois F, Picot M, Guillot B, Bessis D. How much disability is caused by fibrofolliculomas during Birt-Hogg-Dubé Syndrome?. J Eur Acad Dermatol Venereol. 2011;25:940-4 pubmed publisher
    ..Facial fibrofolliculomas (FFs) develop mainly on the face of patients with Birt-Hogg-Dubé syndrome (BHDS) after the second decade and increase in number and size during life...
  33. Pape E, Rezvoy N, Penel N, Salleron J, Martinot V, Guerreschi P, et al. Radiotherapy alone for Merkel cell carcinoma: a comparative and retrospective study of 25 patients. J Am Acad Dermatol. 2011;65:983-90 pubmed publisher
    ..However, surgery may be difficult to perform with tumors located in the head and neck region and/or in elderly patients with comorbidities incompatible with general anesthesia...
  34. Shehata N, Powell J, Dubois J, Hatami A, Rousseau E, Ondrejchak S, et al. Late rebound of infantile hemangioma after cessation of oral propranolol. Pediatr Dermatol. 2013;30:587-91 pubmed publisher
    ..Late proliferation can occur in localized, small, mixed, and deep IH, even after several months of a positive response to propranolol. A second course of propranolol readily controlled the recurrence...
  35. Heffelfinger R, Murchison A, Parkes W, Krein H, Curry J, Evans J, et al. Microvascular free flap reconstruction of orbitocraniofacial defects. Orbit. 2013;32:95-101 pubmed publisher
    ..To examine the etiology, surgical extent and techniques, complications, and outcomes of microvascular free flaps (MFF) in the reconstruction of orbitocraniofacial defects...
  36. Moskalik K, Kozlow A, Demin E, Boiko E. Powerful neodymium laser radiation for the treatment of facial carcinoma: 5 year follow-up data. Eur J Dermatol. 2010;20:738-42 pubmed publisher
    ..1% and 4.6% of patients, respectively. Neodymium laser radiation is a safe and effective means of treating facial carcinomas of stages T1-2N0M0 with good cosmetic results...
  37. Schulz H. [Pigmented lesion on the temple. Pigment cell tumor, basal cell carcinoma, or irritated seborrheic keratosis?]. Hautarzt. 2010;61:1061-2 pubmed publisher
    ..Inflammatory cells and melanophages were present in the papillary dermis, surrounding dilated vessels. Histopathological diagnosis revealed an irritated seborrheic keratosis...
  38. Acioglu E, Acar G, Alimoglu Y, Cansiz H, Dervisoglu S. Myofibroma of the zygomatic bone in an older child: a case report. Ear Nose Throat J. 2011;90:E1-4 pubmed
    ..g., a failure to perform fine-needle aspiration or frozen-section biopsy) may guide the clinician toward a radical surgical procedure rather than a simple excision...
  39. Zvulunov A, McCuaig C, Frieden I, Mancini A, Puttgen K, Dohil M, et al. Oral propranolol therapy for infantile hemangiomas beyond the proliferation phase: a multicenter retrospective study. Pediatr Dermatol. 2011;28:94-8 pubmed publisher
    ..001). No significant side effects were reported. We conclude that propranolol is effective in infantile hemangiomas, including post-proliferative phase, and should be considered as the first-line therapy in that setting...
  40. Camozzato C, Basso F, Duquia R, Boff A, Almeida H. Facial miliary osteoma in HIV patient. An Bras Dermatol. 2011;86:S66-8 pubmed
    ..Computerized tomography of the face revealed small calcifications on the surface consistent with bone formation. Multiple facial osteomas are rare as well as its association with HIV virus infection...
  41. García Gutiérrez M, Toussaint Caire S, González Sánchez P, Ortiz Hidalgo C. Multiple desmoplastic cellular neurothekeomas localized to the face of a 16-year-old boy. Am J Dermatopathol. 2010;32:841-5 pubmed
    ..5, and factor XIIIa and were negative for CD68, glial fibrillary acid protein (GFAP), S-100, HMB-45, epithelial membrane antigen, actin, and CD57 consistent with a diagnosis of multiple desmoplastic cellular neurothekeomas...
  42. Hussain W, Hafiji J, Salmon P. Frontalis-based island pedicle flaps for the single-stage repair of large defects of the forehead and frontal scalp. Br J Dermatol. 2012;166:771-4 pubmed publisher
    ..Medium- to large-sized surgical defects of the forehead and frontal scalp provide a challenge for the reconstructive surgeon...
  43. Junck M, Huerter C, Sarma D. Rapidly growing hemorrhagic papule on the cheek of a 54-year-old man. Dermatol Online J. 2011;17:11 pubmed
    ..Because the literature contains reports of nodular melanoma mimicking the presentation of a pyogenic granuloma, all such lesions should be biopsied for histopathologic diagnosis...
  44. Smart D, Taintor A, Kelly M, Lyon V, Segura A, Jensen J, et al. Microcystic adnexal carcinoma: the first reported congenital case. Pediatr Dermatol. 2011;28:35-8 pubmed publisher
    ..Our patient is unique in that the lesion was present at birth, making this the youngest case of microcystic adenexal carcinoma reported...
  45. Angulo J, Serra Guillen C, Traves V, Botella Estrada R, Sanmartin O, Llombart B, et al. [Mohs micrographic surgery for repeat excision of basal cell carcinomas on the head with positive margins]. Actas Dermosifiliogr. 2011;102:797-804 pubmed publisher
    ..Factors may exist that help to choose the best therapeutic approach for basal cell carcinomas on the head in which positive margins are observed following excision...
  46. Newlove T, Cook J. Safety of staged interpolation flaps after Mohs micrographic surgery in an outpatient setting: a single-center experience. Dermatol Surg. 2013;39:1671-82 pubmed publisher
    ..To establish the safety of staged interpolation flaps performed in an outpatient dermatologic clinic setting...
  47. Choi W, Stetsenko G, Zhang J, Olerud J, Argenyi Z, George E. Cutaneous angiosarcoma clinically presenting as progressive solid facial edema in a 43-year-old male. Dermatol Online J. 2013;19:20409 pubmed
    ..This is a rare example of cutaneous angiosarcoma presenting as progressive solid facial edema, which underscores the diverse range of clinical manifestations associated with this neoplasm. ..
  48. Kai A, Richards T, Coleman A, Mallipeddi R, Barlow R, Craythorne E. Five-year recurrence rate of lentigo maligna after treatment with imiquimod. Br J Dermatol. 2016;174:165-8 pubmed publisher
    ..Clinical assessment of clearance is difficult. Histological confirmation is preferred but risks sampling error and missing areas of invasion. Confocal microscopy can be used to assess entire lesions...
  49. Schaffer J, Orlow S. Radiation therapy for high-risk squamous cell carcinomas in patients with xeroderma pigmentosum: report of two cases and review of the literature. Dermatology. 2011;223:97-103 pubmed publisher
  50. Sago T, Ono K, Harano N, Furuta Hidaka K, Hitomi S, Nunomaki M, et al. Distinct time courses of microglial and astrocytic hyperactivation and the glial contribution to pain hypersensitivity in a facial cancer model. Brain Res. 2012;1457:70-80 pubmed publisher
  51. Korfage A, Stellingsma K, Jansma J, Vissink A, Raghoebar G. Oral rehabilitation with implant-based prostheses of two adult patients treated for childhood rhabdomyosarcoma. Support Care Cancer. 2011;19:1477-80 pubmed publisher
    ..As a result of this treatment, facial growth retardation and oral abnormalities such as malformation of teeth and microstomia can cause esthetic and functional problems...
  52. Xue L, Wang X. [Application of electrochemical therapy in high-flow vascular malformation in maxillofacial region]. Zhonghua Zheng Xing Wai Ke Za Zhi. 2011;27:28-30 pubmed
    ..To explore the therapeutic effect of electrochemical therapy(ECT) for high-flow vascular malformation in maxillofacial region...
  53. Mamelak A, Goldberg L, Katz T, Graves J, Arnon O, Kimyai Asadi A. Desmoplastic trichoepithelioma. J Am Acad Dermatol. 2010;62:102-6 pubmed publisher
    ..Desmoplastic trichoepithelioma (DTE) is an uncommon adnexal tumor usually found on the face of young women...