carcinoma

Summary

Summary: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for "cancer."

Top Publications

  1. Li H, Fan H, Wang Z, Zheng J, Cao W. Potentiation of scutellarin on human tongue carcinoma xenograft by low-intensity ultrasound. PLoS ONE. 2013;8:e59473 pubmed publisher
    ..Tumor-bearing Balb/c mice and SAS human-tongue squamous carcinoma cell suspensions were used for the in vivo and in vitro experiments, respectively...
  2. Ganly I, Ricarte Filho J, Eng S, Ghossein R, Morris L, Liang Y, et al. Genomic dissection of Hurthle cell carcinoma reveals a unique class of thyroid malignancy. J Clin Endocrinol Metab. 2013;98:E962-72 pubmed publisher
    ..expression showed the 3 groups of Hurthle tumors (Hurthle cell adenoma [HA], minimally invasive Hurthle cell carcinoma [HMIN], and widely invasive Hurthle cell carcinoma [HWIDE] clustered separately with a marked difference between ..
  3. Carroll C, Badu Nkansah A, Hunley T, Baradaran Heravi A, Cortez D, Frangoul H. Schimke Immunoosseous Dysplasia associated with undifferentiated carcinoma and a novel SMARCAL1 mutation in a child. Pediatr Blood Cancer. 2013;60:E88-90 pubmed publisher
    ..We report a child with SIOD and a novel S859P missense mutation in SMARCAL1 who developed undifferentiated carcinoma of the sinus.
  4. Hlaváč V, Brynychová V, Vaclavikova R, Ehrlichova M, Vrana D, Pecha V, et al. The expression profile of ATP-binding cassette transporter genes in breast carcinoma. Pharmacogenomics. 2013;14:515-29 pubmed publisher
    ..A major goal of our study was to investigate associations between the expression of ABC transporters and outcome of breast carcinoma patients.
  5. Lee J, Kim Y, Choi J, Kim Y. The association between papillary thyroid carcinoma and histologically proven Hashimoto's thyroiditis: a meta-analysis. Eur J Endocrinol. 2013;168:343-9 pubmed publisher
    No consensus exists on the association between papillary thyroid carcinoma (PTC) and Hashimoto's thyroiditis (HT). To resolve this controversy, this study aimed to evaluate the relationship between the two conditions using a meta-analysis.
  6. Meng F, Li H, Zhou R, Luo C, Hu Y, Lou G. LAPTM4B gene polymorphism and endometrial carcinoma risk and prognosis. Biomarkers. 2013;18:136-43 pubmed publisher
    ..study, we investigated the relationship between LAPTM4B gene polymorphism and susceptibility to endometrial carcinoma (EC)...
  7. Sasahira T, Ueda N, Kurihara M, Matsushima S, Ohmori H, Fujii K, et al. Tropomyosin receptor kinases B and C are tumor progressive and metastatic marker in colorectal carcinoma. Hum Pathol. 2013;44:1098-106 pubmed publisher
    ..05), respectively. Both TrkB and TrkC showed antiapoptotic effect (P < .05). These results suggest that TrkB and TrkC have a tumor progressive function and may be a useful diagnostic and therapeutic target in CRC. ..
  8. Tan V, Lewis S, Adams J, Martin R. Association of fascin-1 with mortality, disease progression and metastasis in carcinomas: a systematic review and meta-analysis. BMC Med. 2013;11:52 pubmed publisher
    ..Fascin-1 promotes filopodia formation, migration and invasion in carcinoma cells; in mouse xenograft tumor models it contributes to metastasis...
  9. Nam S, Shin J, Han B, Ko E, Ko E, Hahn S, et al. Preoperative ultrasonographic features of papillary thyroid carcinoma predict biological behavior. J Clin Endocrinol Metab. 2013;98:1476-82 pubmed publisher
    Although ultrasound (US) features of papillary thyroid carcinoma (PTC) are well established, little is known regarding biological behavior according US features...

More Information

Publications114 found, 100 shown here

  1. Zhong M, Bian Z, Wu Z. miR-30a suppresses cell migration and invasion through downregulation of PIK3CD in colorectal carcinoma. Cell Physiol Biochem. 2013;31:209-18 pubmed publisher
    ..The aim of this study was to determine the regulation and function of miR-30a in colorectal carcinoma (CRC) metastasis. The expression of miR-30a was detected in CRC cell lines and samples by qRT-PCR...
  2. Lee Y, Lee J. Prognostic value of epidermal growth factor receptor, p53 and galectin-3 expression in papillary thyroid carcinoma. J Int Med Res. 2013;41:825-34 pubmed publisher
    ..and prognostic value of epidermal growth factor receptor (EGFR), p53 and galectin-3 in papillary thyroid carcinoma (PTC)...
  3. Shen Z, Jiang X, Zeng C, Zheng S, Luo B, Zeng Y, et al. High expression of ubiquitin-conjugating enzyme 2C (UBE2C) correlates with nasopharyngeal carcinoma progression. BMC Cancer. 2013;13:192 pubmed publisher
    ..However, the role of UBE2C in human nasopharyngeal carcinoma (NPC) is unclear...
  4. Li X, Lu Y, Chen Y, Lu W, Xie X. MicroRNA profile of paclitaxel-resistant serous ovarian carcinoma based on formalin-fixed paraffin-embedded samples. BMC Cancer. 2013;13:216 pubmed publisher
    ..profile related to paclitaxel-sensitivity in formalin-fixed paraffin-embedded (FFPE) samples of serous ovarian carcinoma (OC) patients...
  5. Wu G, Wang J, Zhou Z, Li T, Tang F. Combined staining for immunohistochemical markers in the diagnosis of papillary thyroid carcinoma: improvement in the sensitivity or specificity?. J Int Med Res. 2013;41:975-83 pubmed publisher
    ..cell (HBME)-1 and tyrosine kinase-type cell surface receptor HER2 (HER-2/neu) to differentiate papillary thyroid carcinoma (PTC) from benign thyroid nodules...
  6. Zagzag J, Pollack A, Dultz L, Dhar S, Ogilvie J, Heller K, et al. Clinical utility of immunohistochemistry for the detection of the BRAF v600e mutation in papillary thyroid carcinoma. Surgery. 2013;154:1199-204; discussion 1204-5 pubmed publisher
    ..It provides a potentially rapid, easily applicable, and economic alternative to current techniques. ..
  7. Elesawy B, Abd El Hafez A, Shawky A, Arafa M. Immunohistochemistry-based subtyping of breast carcinoma in Egyptian women: a clinicopathologic study on 125 patients. Ann Diagn Pathol. 2014;18:21-6 pubmed publisher
    Breast carcinoma is a heterogeneous disease affected by patients' ethnicity. Gene expression analysis identified several molecular subtypes, and similar subtyping has now been found to be feasible using immunohistochemistry...
  8. Messer J, Shariat S, Dinney C, Novara G, Fradet Y, Kassouf W, et al. Female gender is associated with a worse survival after radical cystectomy for urothelial carcinoma of the bladder: a competing risk analysis. Urology. 2014;83:863-7 pubmed publisher
    ..To determine the association of gender with outcome after radical cystectomy for patients with bladder cancer...
  9. Davidson B, Trope C, Reich R. The clinical and diagnostic role of microRNAs in ovarian carcinoma. Gynecol Oncol. 2014;133:640-6 pubmed publisher
    ..Data regarding the expression and clinical relevance of miRNAs and the miRNA-regulating machinery in ovarian carcinoma has been rapidly expanding in recent years. This review presents current knowledge in this area...
  10. Sonpavde G, Pond G, Fougeray R, Choueiri T, Qu A, Vaughn D, et al. Time from prior chemotherapy enhances prognostic risk grouping in the second-line setting of advanced urothelial carcinoma: a retrospective analysis of pooled, prospective phase 2 trials. Eur Urol. 2013;63:717-23 pubmed publisher
    Outcomes for patients in the second-line setting of advanced urothelial carcinoma (UC) are dismal...
  11. Gillissen B, Richter A, Overkamp T, Essmann F, Hemmati P, Preissner R, et al. Targeted therapy of the XIAP/proteasome pathway overcomes TRAIL-resistance in carcinoma by switching apoptosis signaling to a Bax/Bak-independent 'type I' mode. Cell Death Dis. 2013;4:e643 pubmed publisher
    ..Pharmacological manipulation of XIAP therefore is a promising strategy to sensitize cells for TRAIL and to overcome TRAIL-resistance in case of central defects in the intrinsic apoptosis-signaling pathway. ..
  12. Babjuk M, Burger M, Zigeuner R, Shariat S, van Rhijn B, Comperat E, et al. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2013. Eur Urol. 2013;64:639-53 pubmed publisher
    ..Tumours staged as Ta, T1, or carcinoma in situ (CIS) are grouped as NMIBC...
  13. Otto W, May M, Fritsche H, Dragun D, Aziz A, Gierth M, et al. Analysis of sex differences in cancer-specific survival and perioperative mortality following radical cystectomy: results of a large German multicenter study of nearly 2500 patients with urothelial carcinoma of the bladder. Gend Med. 2012;9:481-9 pubmed publisher
    Outcome of patients with urothelial carcinoma of the bladder (UCB) varies between sexes. Although overall incidence is higher in men, cancer-specific survival (CSS) has been suggested to be lower in women...
  14. Vishchuk O, Ermakova S, Zvyagintseva T. The effect of sulfated (1?3)-?-l-fucan from the brown alga Saccharina cichorioides Miyabe on resveratrol-induced apoptosis in colon carcinoma Cells. Mar Drugs. 2013;11:194-212 pubmed publisher
    ..Taken together, these results demonstrate that the combination of the algal fucoidan with resveratrol may provide a potential therapy against human colon cancer...
  15. Alexiev B, Drachenberg C. Tubulocystic carcinoma of the kidney: a histologic, immunohistochemical, and ultrastructural study. Virchows Arch. 2013;462:575-81 pubmed publisher
    Tubulocystic carcinoma of the kidney (TCCK) is a tumor entity, which is not yet included in the WHO classification of renal tumors. The histogenesis of this neoplasm is uncertain...
  16. Staton C, Koay I, Wu J, Hoh L, Reed M, Brown N. Neuropilin-1 and neuropilin-2 expression in the adenoma-carcinoma sequence of colorectal cancer. Histopathology. 2013;62:908-15 pubmed publisher
    ..However, the precise role of NRP1 and NRP2 in the adenoma-carcinoma sequence (ACS) of colorectal cancer remains unclear, and we aimed to determine this in surgical specimens ..
  17. Rong G, Kang H, Wang Y, Hai T, Sun H. Candidate markers that associate with chemotherapy resistance in breast cancer through the study on Taxotere-induced damage to tumor microenvironment and gene expression profiling of carcinoma-associated fibroblasts (CAFs). PLoS ONE. 2013;8:e70960 pubmed publisher
    Recently, emerging evidence has suggested that carcinoma-associated fibroblasts (CAFs) could contribute to chemotherapy resistances in breast cancer treatment...
  18. Shi Z, Zhang Y, Shang L, Hao J, Zhang T, Wang B, et al. Genomic profiling of rectal adenoma and carcinoma by array-based comparative genomic hybridization. BMC Med Genomics. 2012;5:52 pubmed publisher
    ..The present study aims to investigate the genomic alterations in rectal adenoma and carcinoma. We detected the genomic changes of 8 rectal adenomas and 8 carcinomas using array CGH...
  19. Morris K, Khan H, Ahmad A, Weston L, Nofchissey R, Pinchuk I, et al. G-CSF and G-CSFR are highly expressed in human gastric and colon cancers and promote carcinoma cell proliferation and migration. Br J Cancer. 2014;110:1211-20 pubmed publisher
    ..expression was examined in human gastric and colon tumours and by tumour-derived stromal myofibroblasts and carcinoma cells. G-CSFR expression was examined on carcinoma cells isolated from human tissues...
  20. Milovanovic J, Djukic V, Milovanovic A, Jotic A, Banko B, Jesic S, et al. Clinical outcome of early glottic carcinoma in Serbia. Auris Nasus Larynx. 2013;40:394-9 pubmed publisher
    Proposed methods for treating early glottic carcinoma are cordectomy through laryngofissure, laser cordectomy, and radiotherapy...
  21. Abdou A, El Wahed M, Kandil M, Samaka R, Elkady N. Immunohistochemical analysis of the role and relationship between Notch-1 and Oct-4 expression in urinary bladder carcinoma. APMIS. 2013;121:982-96 pubmed publisher
    ..This study aimed at an evaluation of Oct-4 and Notch-1 expression in both carcinoma and stromal cells of 83 cases of primary bladder carcinoma and to study the relationship between them...
  22. Ghansah T, Vohra N, Kinney K, Weber A, Kodumudi K, Springett G, et al. Dendritic cell immunotherapy combined with gemcitabine chemotherapy enhances survival in a murine model of pancreatic carcinoma. Cancer Immunol Immunother. 2013;62:1083-91 pubmed publisher
  23. Li Y, Wei W, Shen H, Hu W. The study of inducing apoptosis effect of fructose 1,6-bisphosphate on the papillary thyroid carcinoma cell and its related mechanism. Tumour Biol. 2014;35:4539-44 pubmed publisher
    ..apoptosis-inducing effect of fructose 1,6-bisphosphate (F1,6BP) on the related mechanism of papillary thyroid carcinoma W3 and T cells...
  24. Polanska U, Orimo A. Carcinoma-associated fibroblasts: non-neoplastic tumour-promoting mesenchymal cells. J Cell Physiol. 2013;228:1651-7 pubmed publisher
    Cancerous stroma coevolves alongside tumour progression, thereby promoting the malignant conversion of epithelial carcinoma cells...
  25. Pozzi V, Sartini D, Morganti S, Giuliante R, Di Ruscio G, Santarelli A, et al. RNA-mediated gene silencing of nicotinamide N-methyltransferase is associated with decreased tumorigenicity in human oral carcinoma cells. PLoS ONE. 2013;8:e71272 pubmed publisher
    Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer. Despite progress in the treatment of OSCC, overall survival has not improved substantially in the last three decades...
  26. Qu Q, Huang Q, Xu J, Duan L, Zhu Y, Zhang X. CD40 signal regulates CXCR4 mediating ovarian carcinoma cell migration: implications for extrapelvic metastastic factors. Oncol Res. 2013;20:383-92 pubmed publisher
    ..Furthermore, concomitant expression of CXCR4/CD40 in ovarian carcinoma tissues had stronger correlation with pelvic metastasis than did each alone...
  27. Wu S, Qian W, Zhang J, Yang Y, Liu Y, Dong Y, et al. Network motifs in the transcriptional regulation network of cervical carcinoma cells respond to EGF. Arch Gynecol Obstet. 2013;287:771-7 pubmed publisher
    Cervical carcinoma is the second most prevalent and the fifth most deadly malignancy seen in women worldwide...
  28. Wang Z, Portier B, Gruver A, Bui S, Wang H, Su N, et al. Automated quantitative RNA in situ hybridization for resolution of equivocal and heterogeneous ERBB2 (HER2) status in invasive breast carcinoma. J Mol Diagn. 2013;15:210-9 pubmed publisher
    Patient management based on HER2 status in breast carcinoma is an archetypical example of personalized medicine but remains hampered by equivocal testing and intratumoral heterogeneity...
  29. Hayashi A, Hiatari R, Tsuji T, Ohashi K, Mizuno K. p63RhoGEF-mediated formation of a single polarized lamellipodium is required for chemotactic migration in breast carcinoma cells. FEBS Lett. 2013;587:698-705 pubmed publisher
    ..and AAH33666) were found to be required for the serum-induced chemotactic migration of MDA-MB-231 human breast carcinoma cells...
  30. Wang J, Li X, Gao X, An S, Liu H, Liang J, et al. Expression of MMP-13 is associated with invasion and metastasis of papillary thyroid carcinoma. Eur Rev Med Pharmacol Sci. 2013;17:427-35 pubmed
    ..The data suggest that MMP-13 is associated with thyroid tumour invasion and metastasis and it may be a potential target for therapeutic intervention. ..
  31. Li Q, Lee R, Liang H, Wang G, Li J, Zhong Y, et al. ?-Elemene enhances susceptibility to cisplatin in resistant ovarian carcinoma cells via downregulation of ERCC-1 and XIAP and inactivation of JNK. Int J Oncol. 2013;43:721-8 pubmed publisher
    ..It also increases cisplatin cytotoxicity and enhances cisplatin sensitivity in resistant human carcinoma cells. However, little is known about the mechanism of its action...
  32. Martin L, Marples B, Davies A, Atzberger A, Edwards C, Lynch T, et al. DNA mismatch repair protein MSH2 dictates cellular survival in response to low dose radiation in endometrial carcinoma cells. Cancer Lett. 2013;335:19-25 pubmed publisher
    ..The low-dose radioresponse of MSH2 isogenic endometrial carcinoma cell lines was examined...
  33. Lee S, Jung C, Kim T, Bae J, Jung S, Choi Y, et al. Molecular genotyping of follicular variant of papillary thyroid carcinoma correlates with diagnostic category of fine-needle aspiration cytology: values of RAS mutation testing. Thyroid. 2013;23:1416-22 pubmed publisher
    The follicular variant of papillary thyroid carcinoma (FVPTC) presents distinct histologic subtypes and molecular genotyping. The preoperative diagnosis of FVPTC through fine-needle aspiration cytology (FNAC) is challenging.
  34. Mauri G, Cova L, Tondolo T, Ierace T, Baroli A, Di Mauro E, et al. Percutaneous laser ablation of metastatic lymph nodes in the neck from papillary thyroid carcinoma: preliminary results. J Clin Endocrinol Metab. 2013;98:E1203-7 pubmed publisher
    ..Percutaneous laser ablation (PLA) may be useful in treating patients with metachronous metastatic lymph nodes in the neck...
  35. Swierniak M, Wojcicka A, Czetwertyńska M, Stachlewska E, Maciag M, Wiechno W, et al. In-depth characterization of the microRNA transcriptome in normal thyroid and papillary thyroid carcinoma. J Clin Endocrinol Metab. 2013;98:E1401-9 pubmed publisher
    ..study was to provide a comprehensive view of the microRNA transcriptome in normal thyroid and papillary thyroid carcinoma (PTC)...
  36. Lim D, Oliva E. Precursors and pathogenesis of ovarian carcinoma. Pathology. 2013;45:229-42 pubmed publisher
    ..carcinomas and Brenner tumours, are generally indolent and tend to be genetically stable, although clear cell carcinoma would probably belong to an intermediate category...
  37. Pan X, Li Y, Feng J, Wang X, Hao B, Shi R, et al. A functional polymorphism T309G in MDM2 gene promoter, intensified by Helicobacter pylori lipopolysaccharide, is associated with both an increased susceptibility and poor prognosis of gastric carcinoma in Chinese patients. BMC Cancer. 2013;13:126 pubmed publisher
    ..of this study was to investigate whether MDM2 SNP309 is associated with susceptibility and prognosis of gastric carcinoma in Chinese patients...
  38. Hofstetter G, Concin N, Braicu I, Chekerov R, Sehouli J, Cadron I, et al. The time interval from surgery to start of chemotherapy significantly impacts prognosis in patients with advanced serous ovarian carcinoma - analysis of patient data in the prospective OVCAD study. Gynecol Oncol. 2013;131:15-20 pubmed publisher
    ..24 (95% confidence interval 1.08-4.66), P=0.031]. Our findings suggest that delayed initiation of chemotherapy might compromise overall survival in patients with advanced serous ovarian cancer, especially when suboptimally debulked. ..
  39. Chung S, Lee J, Lee H, Park S, Kim S, Ryu H. Cytomorphological factors and BRAF mutation predicting risk of lymph node metastasis in preoperative liquid-based fine needle aspirations of papillary thyroid carcinoma. Acta Cytol. 2013;57:252-8 pubmed publisher
    Preoperative fine needle aspiration biopsy (FNAB) has become the initial diagnostic method for papillary thyroid carcinoma (PTC)...
  40. Grivas P, Hussain M, Hafez K, Daignault Newton S, Wood D, Lee C, et al. A phase II trial of neoadjuvant nab-paclitaxel, carboplatin, and gemcitabine (ACaG) in patients with locally advanced carcinoma of the bladder. Urology. 2013;82:111-7 pubmed publisher
    ..carboplatin, gemcitabine (ACaG) followed by cystectomy in patients with muscle-invasive urothelial carcinoma of the bladder...
  41. Özden F, Saygin C, Uzunaslan D, Onal B, Durak H, Aki H. Expression of MMP-1, MMP-9 and TIMP-2 in prostate carcinoma and their influence on prognosis and survival. J Cancer Res Clin Oncol. 2013;139:1373-82 pubmed publisher
    ..and TIMP-2 on different clinicopathologic variables and disease-free survival (DFS) of patients with prostate carcinoma. Hundred and forty-five cases are included in the study, and levels of MMP/TIMP expressions are assessed in ..
  42. Liu H, Zhu Y, Zhang T, Zhao Z, Zhao Y, Cheng P, et al. Anti-tumor effects of atractylenolide I isolated from Atractylodes macrocephala in human lung carcinoma cell lines. Molecules. 2013;18:13357-68 pubmed publisher
    ..In conclusion, our results demonstrated that ATL-I has significant antitumor activity in lung carcinoma cells, and the possible mechanism of action may be related to apoptosis induced by ATL-I via a mitochondria-..
  43. Remo A, Pancione M, Zanella C, Vendraminelli R. Molecular pathology of colorectal carcinoma. A systematic review centred on the new role of the pathologist. Pathologica. 2012;104:432-41 pubmed
    Colorectal carcinoma (CRC) is the second most frequent malignant disease in developed countries. Many aetiological factors have been reported in CRC development including genetic or non-genetic (environmental) elements...
  44. Boyraz G, Selcuk I, Yazıcıoğlu A, Tuncer Z. Ovarian carcinoma associated with endometriosis. Eur J Obstet Gynecol Reprod Biol. 2013;170:211-3 pubmed publisher
    Previous studies have suggested an association between endometriosis and development of ovarian cancer. A study was performed to evaluate the cases of ovarian carcinoma associated with endometriosis.
  45. Lim A, Corry J, Collins M, Peters L, Hicks R, D Costa I, et al. A phase II study of induction carboplatin and gemcitabine followed by chemoradiotherapy for the treatment of locally advanced nasopharyngeal carcinoma. Oral Oncol. 2013;49:468-74 pubmed publisher
    To investigate the tolerability and feasibility of induction gemcitabine and carboplatin chemotherapy followed by radiotherapy with concurrent cisplatin in patients with locally advanced nasopharyngeal carcinoma.
  46. Chen Y, Cheng W, Chang M, Lin H, Huang C, Chien C, et al. Interferon-gamma in ascites could be a predictive biomarker of outcome in ovarian carcinoma. Gynecol Oncol. 2013;131:63-8 pubmed publisher
    ..The aim of this study was to investigate whether the selected target cytokine expression levels in ascites could serve as an immune biomarker for predicting outcomes in ovarian cancer...
  47. Gonzalez M, Moore H, Li X, Toy K, Huang W, Sabel M, et al. EZH2 expands breast stem cells through activation of NOTCH1 signaling. Proc Natl Acad Sci U S A. 2014;111:3098-103 pubmed publisher
    ..These data reveal a functional and mechanistic link between EZH2 levels, NOTCH1 signaling activation, and TICs, and provide previously unidentified evidence that EZH2 enhances breast cancer initiation. ..
  48. Das S, Czarnek M, Bzowska M, Mezyk Kopec R, Stalinska K, Wyroba B, et al. ADAM17 silencing in mouse colon carcinoma cells: the effect on tumoricidal cytokines and angiogenesis. PLoS ONE. 2012;7:e50791 pubmed publisher
    ..Here we show, using MC38CEA murine colon carcinoma model, that ADAM17 also regulates tumor angiogenesis and cytokine profile...
  49. Chaux A, Comperat E, Varinot J, Hicks J, Lecksell K, Solus J, et al. High levels of phosphatase and tensin homolog expression are associated with tumor progression, tumor recurrence, and systemic metastases in pT1 urothelial carcinoma of the bladder: a tissue microarray study of 156 patients treated by transurethral r. Urology. 2013;81:116-22 pubmed publisher
  50. Xu C, Shen J, Xie S, Jiang Z, Huang L, Wang L. Positive expression of Lin28 is correlated with poor survival in gastric carcinoma. Med Oncol. 2013;30:382 pubmed publisher
    The purpose of this study was to investigate the expression of Lin28 in gastric carcinoma and to assess its clinical significance...
  51. Rossi E, Martini M, Capodimonti S, Straccia P, Cenci T, Lombardi C, et al. Diagnostic and prognostic value of immunocytochemistry and BRAF mutation analysis on liquid-based biopsies of thyroid neoplasms suspicious for carcinoma. Eur J Endocrinol. 2013;168:853-9 pubmed publisher
    ..The introduction of the liquid-based cytology (LBC) may simplify the application of these techniques to thyroid cytology...
  52. Perrin C, Langbein L, Ambrossetti D, Erfan N, Schweizer J, Michiels J. Onychocytic carcinoma: a new entity. Am J Dermatopathol. 2013;35:679-84 pubmed publisher
    ..We have proposed the name onychocytic carcinoma for this singular adnexal neoplasm...
  53. Jing F, Liang J, Liang Z, Meng C, Long W, Li X, et al. BRAF(V600E) mutation is not a positive predictor for distant metastasis in sporadic papillary thyroid carcinoma. Chin Med J (Engl). 2013;126:3013-8 pubmed
    BRAF(V600E) mutation is correlated with local aggressive clinicopathological features in papillary thyroid carcinoma; yet the relationship between this genetic variation and distant papillary thyroid carcinoma metastasis was unclear...
  54. Guillemot E, Karimdjee Soilihi B, Pradelli E, Benchetrit M, Goguet Surmenian E, Millet M, et al. CXCR7 receptors facilitate the progression of colon carcinoma within lung not within liver. Br J Cancer. 2012;107:1944-9 pubmed publisher
    ..Chemokine-receptor pairs have a critical role in determining the metastatic progression of tumours. Our hypothesis was that disruption of CXCR7/CXCR7 ligands axis could lead to a decrease in CRC metastases...
  55. Dai F, Zhang Y, Zhu X, Shan N, Chen Y. Anticancer role of MUC1 aptamer-miR-29b chimera in epithelial ovarian carcinoma cells through regulation of PTEN methylation. Target Oncol. 2012;7:217-25 pubmed publisher
    ..Our study indicated that Chi-29b chimera can effectively exert antitumor effect through specific delivery of miR-29b into OVCAR-3 tumor cells, subsequently reexpressing PTEN gene and inducing cell apoptosis...
  56. Alvarado Cabrero I, Stolnicu S, Kiyokawa T, Yamada K, Nikaido T, Santiago Payán H. Carcinoma of the fallopian tube: Results of a multi-institutional retrospective analysis of 127 patients with evaluation of staging and prognostic factors. Ann Diagn Pathol. 2013;17:159-64 pubmed publisher
    The aim of this study was to determine the impact of prognostic factors in primary fallopian tube carcinoma (PFTC). All cases of PFTC diagnosed between 1990 and 2010 were retrieved from the files of 6 academic centers...
  57. Das B, Khan Z. Periampullary carcinoma: better prognosis with early pre-stenting referral to surgery. Mymensingh Med J. 2013;22:110-5 pubmed
    ..and to assess the effect of delayed referral on management and prognosis of patients with periampullary carcinoma. Patients with histopathologically proved periampullary carcinoma (n=41) during the period January 2010 to ..
  58. Ducoudray R, Tresallet C, Godiris Petit G, Tissier F, Leenhardt L, Menegaux F. Prophylactic lymph node dissection in papillary thyroid carcinoma: is there a place for lateral neck dissection?. World J Surg. 2013;37:1584-91 pubmed publisher
    Cervical lymph node (LN) metastases are common in patients with papillary thyroid carcinoma (PTC), and they have a negative impact on recurrence. The management of preoperatively node-negative (N0) PTC is still controversial...
  59. Pyo J, Kang G, Kim D, Park C, Kim J, Sohn J. The prognostic relevance of psammoma bodies and ultrasonographic intratumoral calcifications in papillary thyroid carcinoma. World J Surg. 2013;37:2330-5 pubmed publisher
    ..The aim of the present study was to determine the clinicopathological significance of PB and the correlation between PB and ultrasonographic intratumoral calcification in PTC...
  60. Francis J, Thomsen M, Taketo M, Swain A. ?-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma. PLoS Genet. 2013;9:e1003180 pubmed publisher
    ..Catenin overexpression in combination with Pten loss was able to drive progression to invasive carcinoma together with squamous metaplasia...
  61. Laco J, Svajdler M, Andrejs J, Hrubala D, Hácová M, Vanecek T, et al. Mammary analog secretory carcinoma of salivary glands: a report of 2 cases with expression of basal/myoepithelial markers (calponin, CD10 and p63 protein). Pathol Res Pract. 2013;209:167-72 pubmed publisher
    Mammary analog secretory carcinoma (MASC) of salivary glands is a recently described neoplasm with favorable outcome...
  62. Ye F, Huang G, Fu M, Ma Y, Kang H. [Expression of SOX2 protein and its clinical significance in laryngeal carcinoma]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013;27:136-9 pubmed
    To investigate the expression of SOX2 in laryngeal carcinoma and analyze the relation of SOX2 and clinical factors.
  63. Zhang J, Wang Y, Li D, Jing S. Notch and TGF-?/Smad3 pathways are involved in the interaction between cancer cells and cancer-associated fibroblasts in papillary thyroid carcinoma. Tumour Biol. 2014;35:379-85 pubmed publisher
    ..identify the signaling pathways that are involved in tumor-stromal cell interactions in human papillary thyroid carcinoma (PTC)...
  64. Li W, Liu M, Feng Y, Huang Y, Xu Y, Che J, et al. High expression of Notch ligand Jagged2 is associated with the metastasis and recurrence in urothelial carcinoma of bladder. Int J Clin Exp Pathol. 2013;6:2430-40 pubmed
    ..Recent studies found its vital role in tumor metastasis in breast cancer; however, its expression profile and its prognostic value in urothelial carcinoma of bladder have not been investigated.
  65. Fokas E, Liersch T, Fietkau R, Hohenberger W, Beissbarth T, Hess C, et al. Tumor regression grading after preoperative chemoradiotherapy for locally advanced rectal carcinoma revisited: updated results of the CAO/ARO/AIO-94 trial. J Clin Oncol. 2014;32:1554-62 pubmed publisher
    ..described the prognostic impact of tumor regression grading (TRG) on the outcome of patients with rectal carcinoma treated with preoperative chemoradiotherapy (CRT) in the CAO/ARO/AIO-94 trial...
  66. Cohen D, Dabbs D, Cooper K, Amin M, Jones T, Jones M, et al. Interobserver agreement among pathologists for semiquantitative hormone receptor scoring in breast carcinoma. Am J Clin Pathol. 2012;138:796-802 pubmed publisher
    ..85 (95% confidence interval [CI] = 0.79-0.90) for ER and 0.87 (95% CI = 0.82-0.92) for PR. Because the H-score provides a continuous measure of tumor hormone receptor content, we suggest universal adoption of this method...
  67. Shoae Hassani A, Mortazavi Tabatabaei S, Sharif S, Madadi S, Rezaei Khaligh H, Verdi J. Recombinant ? bacteriophage displaying nanobody towards third domain of HER-2 epitope inhibits proliferation of breast carcinoma SKBR-3 cell line. Arch Immunol Ther Exp (Warsz). 2013;61:75-83 pubmed publisher
    ..study was to produce lambda (?) bacteriophage displaying high-affinity nanobody against HER-2 expressing breast carcinoma cells. Bacteriophage ? is a temperate phage with inherent biological safety in mammalian cells...
  68. Lu Y, Sun G, Liu G, Shi Y, Han Y, Yu F, et al. Clinical significance of mannose-binding lectin expression in thyroid carcinoma tissues. Pathol Oncol Res. 2013;19:259-66 pubmed publisher
    ..Tissue specimens from 45 thyroid carcinoma patients and 45 adenoma patients were recruited for immunohistochemical analysis of MBL expression...
  69. Lv C, Sun W, Sun H, Wei S, Chen R, Wang B, et al. Asperolide A, a marine-derived tetranorditerpenoid, induces G2/M arrest in human NCI-H460 lung carcinoma cells, is mediated by p53-p21 stabilization and modulated by Ras/Raf/MEK/ERK signaling pathway. Mar Drugs. 2013;11:316-31 pubmed publisher
    ..A, a very recently reported marine-derived tetranorditerpenoid, leads to the inhibition of NCI-H460 lung carcinoma cell proliferation by G2/M arrest with the activation of the Ras/Raf/MEK/ERK signaling and p53-dependent p21 ..
  70. Bakrin N, Gilly F, Baratti D, Bereder J, Quenet F, Lorimier G, et al. Primary peritoneal serous carcinoma treated by cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy. A multi-institutional study of 36 patients. Eur J Surg Oncol. 2013;39:742-7 pubmed publisher
    Primary peritoneal serous carcinoma (PPSC) is a rare condition, histologically identical to ovarian serous carcinoma and often diagnosed at late stage. There is not any standardized treatment for PPSC...
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    ..However, the contributions of lncRNAs to gastric carcinoma and their functional mechanisms remain largely unknown...
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    ..29. The prognostic value of Mucin-1 expression in ovarian carcinoma remains uncertain...
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    ..Existing scientific research has not yielded a clinically relevant biomarker with predictive capacity beyond grade and stage in bladder cancer...
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    ..receptor (EGFR) pathway plays a critical role in regulating cancer stem-like cells (CSCs) in nasopharyngeal carcinoma (NPC), one of the most common malignant tumors in Southeast Asia...
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    ..study aimed to observe the SXCI frequencies in apparently healthy Chinese females and patients with esophageal carcinoma. DNA was extracted from the peripheral blood cells from 401 Chinese females without a detectable tumor and 143 ..
  79. Lu X, Chen Y, Feng B, Mao X, Yu B, Chu X. Expression and clinical significance of CD73 and hypoxia-inducible factor-1? in gastric carcinoma. World J Gastroenterol. 2013;19:1912-8 pubmed publisher
    To investigate the expression of CD73 and hypoxia-inducible factor-1? (HIF-1?) in human gastric carcinoma, and explore their clinical significance and prognostic value.
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    ..The purpose of this study was to investigate miRNA deregulation in papillary thyroid carcinoma (PTC), particularly with lymph node (LN) metastasis...
  81. Pinho S, Figueiredo J, Cabral J, Carvalho S, Dourado J, Magalhaes A, et al. E-cadherin and adherens-junctions stability in gastric carcinoma: functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V. Biochim Biophys Acta. 2013;1830:2690-700 pubmed
    ..Nevertheless, in a high percentage of gastric carcinoma cases displaying E-cadherin dysfunction, the mechanism responsible for E-cadherin dysregulation is unknown...
  82. Juang H, Chung L, Sung H, Feng T, Lee Y, Chang P, et al. Metallothionein 3: an androgen-upregulated gene enhances cell invasion and tumorigenesis of prostate carcinoma cells. Prostate. 2013;73:1495-506 pubmed publisher
    ..We determined the effects of androgen, cadmium, and arsenic on MT1/2 and MT3 in prostate carcinoma cells, and evaluated the functional effects of MT3 on cell proliferation, invasion, and tumorigenesis.
  83. Ren K, Gou X, Xiao M, Wang M, Liu C, Tang Z, et al. The over-expression of Pim-2 promote the tumorigenesis of prostatic carcinoma through phosphorylating eIF4B. Prostate. 2013;73:1462-9 pubmed publisher
    Cell experiments have found Pim-2 may take part in the tumorigenesis of prostatic carcinoma (PCA). More direct evidences are needed, and the detailed anti-apoptotic mechanism of Pim-2 in PCA cells is still unknown.
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    Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumor that has morphologic features similar to secretory carcinoma of the breast and that also harbors the same ETV6 translocation...
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    Ultrasound-guided percutaneous ethanol ablation (UPEA) of neck nodal metastases (NNM) has rarely been reported in papillary thyroid carcinoma (PTC) patients with advanced localized disease.
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    ..However, the clinical, pathological, and prognostic associations of EZH2 expression in the upper urinary tract carcinoma have not been reported...
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    The early molecular detection of the dysplasia-carcinoma transition may enhance the strength of diagnosis in the case of colonic biopsies...
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    ..HPV features assessed in conjunction with expression of cell-cycle regulators could be helpful, as joint biomarkers, in predicting clinical outcome...
  89. Park B, Park C, Yoon C, Jang S, Chi H, Ryu M, et al. The extended leukocyte differential count using the Cytodiff flow cytometric system reveals that higher CD16+ cytotoxic NK+T lymphocyte levels predict superior survival outcomes in patients with metastatic carcinoma. Cytometry B Clin Cytom. 2013;84:202-4 pubmed publisher
    ..of 16 leukocyte differentials were associated with survival and treatment outcomes in patients with metastatic carcinoma or not...
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    ..about the inhibitory effect of CdSe quantum dots (QDs) on Rho-associated kinase (ROCK) activity in cervical carcinoma HeLa cells associated with the attenuation of the ROCK-c-Myc signaling...
  91. Wang W, Gu J, Shang J, Wang K. Correlation analysis on central lymph node metastasis in 276 patients with cN0 papillary thyroid carcinoma. Int J Clin Exp Pathol. 2013;6:510-5 pubmed
    ..To explore the relationship between sex, age, capsule invasion, tumor size, tumor location, number and central lymph node metastasis...
  92. Yang Y, Wang L, Wang S, Liang S, Chen A, Tang H, et al. Study of metabonomic profiles of human esophageal carcinoma by use of high-resolution magic-angle spinning 1H NMR spectroscopy and multivariate data analysis. Anal Bioanal Chem. 2013;405:3381-9 pubmed publisher
    Esophageal carcinoma (EC) is one of the most common malignant tumors. EC survival has remained disappointingly low because of the high malignancy of esophageal cancer and the lack of obvious clinical symptoms at an early stage...