mucinous cystadenoma

Summary

Summary: A multilocular tumor with mucin secreting epithelium. They are most often found in the ovary, but are also found in the pancreas, appendix, and rarely, retroperitoneal and in the urinary bladder. They are considered to have low-grade malignant potential.

Top Publications

  1. Bassi C, Salvia R, Gumbs A, Butturini G, Falconi M, Pederzoli P. The value of standard serum tumor markers in differentiating mucinous from serous cystic tumors of the pancreas: CEA, Ca 19-9, Ca 125, Ca 15-3. Langenbecks Arch Surg. 2002;387:281-5 pubmed
    ..Examination of preoperative serum tumor markers may help improve preoperative diagnosis...
  2. Cohen Scali F, Vilgrain V, Brancatelli G, Hammel P, Vullierme M, Sauvanet A, et al. Discrimination of unilocular macrocystic serous cystadenoma from pancreatic pseudocyst and mucinous cystadenoma with CT: initial observations. Radiology. 2003;228:727-33 pubmed
    To compare the computed tomographic (CT) appearance of pancreatic unilocular macrocystic serous cystadenoma, mucinous cystadenoma, and pseudocyst to determine if there are findings that assist in the differential diagnosis.
  3. Kim S, Lee J, Kim S, Shin K, Kim Y, An S, et al. Macrocystic neoplasms of the pancreas: CT differentiation of serous oligocystic adenoma from mucinous cystadenoma and intraductal papillary mucinous tumor. AJR Am J Roentgenol. 2006;187:1192-8 pubmed
    ..was to determine useful CT criteria for differentiating serous oligocystic adenomas of the pancreas from other similarly presenting neoplasms, such as mucinous cystadenoma and intraductal papillary mucinous tumor of the branch duct type.
  4. Uddin Z, Yaqoob N, Kayani N, Hasan S. Clear cell carcinoma of ovary with associated mucinous cystadenoma and endometriosis. J Pak Med Assoc. 2007;57:373-5 pubmed
    ..Histological picture showed clear cell carcinoma with areas of mucinous cystadenoma and endometriosis. Clear cell carcinoma is known to be associated with endometriosis...
  5. Colovic N, Jurisic V, Colovic M. Malignant histiocytosis with central nervous system involvement and hepatic mucinous cystadenoma in a single patient with review of the literature. J BUON. 2007;12:539-42 pubmed
    ..We report a case of malignant histiocytosis in a 64-year-old female initially operated on for a mucinous cystadenoma of her liver...
  6. Akan H, Dalva I, Yildiz O, Kutluay L, Gundogdu S, Gungen Y. Mucinous cystadenoma mimicking simple renal parenchymal cyst in a horseshoe kidney. Int J Urol. 2005;12:493-6 pubmed
    We report a case of mucinous cystadenoma in a horseshoe kidney which radiologically resembled a simple renal cyst. In the published literature, three cases of mucinous cystadenoma of renal origin have been reported...
  7. Murakami Y, Uemura K, Morifuji M, Hayashidani Y, Sudo T, Sueda T. Mucinous cystic neoplasm of the pancreas with ovarian-type stroma arising in the head of the pancreas: case report and review of the literature. Dig Dis Sci. 2006;51:629-32 pubmed
  8. Chao A, Chao A, Yen Y, Huang C. Abdominal compartment syndrome secondary to ovarian mucinous cystadenoma. Obstet Gynecol. 2004;104:1180-2 pubmed
    ..With the increase of intraabdominal pressure in abdominal compartment syndrome, all major organ systems are adversely affected, causing a potentially fatal condition...
  9. Shaco Levy R, Tsodikov V, Levy I. Mucinous cystadenoma of the ascending colon: a novel presentation. Scand J Gastroenterol. 2003;38:1193-5 pubmed
    ..This is the first report to describe mucinous cystadenoma of the ascending colon. A 32-year-old female presented with abdominal pain...

More Information

Publications63

  1. Uschuplich V, Hilsenbeck J, Velasco C. Paratesticular mucinous cystadenoma arising from an oviduct-like müllerian remnant: a case report and review of the literature. Arch Pathol Lab Med. 2006;130:1715-7 pubmed
    A mucinous cystadenoma of the paratestis arising from an unequivocal oviduct-like structure in an 18-year-old man is reported. Mucinous cystadenomas of the testis and paratestis are extremely rare benign tumors of controversial origin...
  2. Sawai H, Okada Y, Funahashi H, Matsuo Y, Hayakawa T, Tanaka M, et al. Clinicopathological and immunohistochemical analysis of malignant features in mucinous cystic tumors of the pancreas. Hepatogastroenterology. 2006;53:286-90 pubmed
    ..To investigate the malignancy of mucinous cystic tumors (MCTs) of the pancreas, we examined clinicopathological features and immunohistochemical findings of MCT...
  3. Grapsa D, Kairi Vassilatou E, Hasiakos D, Kondi Pafiti A. Ovarian mucinous cystadenoma with extended calcification in an 11-year-old girl: case report and review of the literature. Clin Exp Obstet Gynecol. 2006;33:181-2 pubmed
    ..We present a case of an ovarian mucinous cystadenoma with extended calcification in a premenarchal 11-year-old girl...
  4. Okamoto Y, Tanaka Y, Tsunoda H, Yoshikawa H, Minami M. Malignant or borderline mucinous cystic neoplasms have a larger number of loculi than mucinous cystadenoma: a retrospective study with MR. J Magn Reson Imaging. 2007;26:94-9 pubmed
    ..To determine whether there is any correlation between the number of loculi and the pathological grade of malignancy in mucinous cystic tumors of the ovary...
  5. Søreide K, Gudlaugsson E, Kjellevold K. [Appendiceal mucinous cystadenoma]. Tidsskr Nor Laegeforen. 2005;125:289-91 pubmed
    ..An appendiceal mucinous neoplasia is sometimes diagnosed during a laparotomy performed on another indication. Frequently, the condition remains undiagnosed until the pathologists' examination...
  6. Prabhuraj A, Basu A, Sistla S, Jagdish S, Jayanthi S. Primary retroperitoneal mucinous cystadenoma in a man. Am J Clin Oncol. 2008;31:519-20 pubmed publisher
  7. Moid F, Jones R. Granulosa cell tumor and mucinous cystadenoma arising in a mature cystic teratoma of the ovary: A unique case report and review of literature. Ann Diagn Pathol. 2004;8:96-101 pubmed
    ..association with granulosa cell tumor have been reported in the literature, and simultaneous occurrence of mucinous cystadenoma and granulosa cell tumor is even rarer...
  8. Yazici M, Etensel B, Gursoy H, Erkus M. Mucinous cystadenoma: a rare abdominal mass in childhood. Eur J Pediatr Surg. 2002;12:330-2 pubmed
    Ovarian masses are uncommon in children. Only 10 - 17 % of them are epithelial tumours. Mucinous cystadenoma in children is a benign cystic ovarian neoplasm, and it is met very rarely in the medical literature...
  9. Ben Ami I, Smorgick N, Tovbin J, Fuchs N, Halperin R, Pansky M. Does intraoperative spillage of benign ovarian mucinous cystadenoma increase its recurrence rate?. Am J Obstet Gynecol. 2010;202:142.e1-5 pubmed publisher
    ..To report a higher than estimated recurrence rate of benign mucinous cystadenomas after complete resection of the first one, and to assess potential risk factors for recurrence after complete surgical excision...
  10. Handra Luca A, Flejou J, Rufat P, Corcos O, Belghiti J, Ruszniewski P, et al. Human pancreatic mucinous cystadenoma is characterized by distinct mucin, cytokeratin and CD10 expression compared with intraductal papillary-mucinous adenoma. Histopathology. 2006;48:813-21 pubmed
    ..To examine cytokeratin, epithelial glycoprotein (mucin) and glycoprotein CD10 expression in benign mucinous cystdenomas (MCAs) in comparison with intraductal papillary mucinous adenomas (IPMAs)...
  11. Shimbo M, Araki K, Kaibuchi T, Kuramochi H, Mori I. Mucinous cystadenoma of the testis. J Urol. 2004;172:146-7 pubmed
  12. Sri Paran T, Mortell A, Devaney D, Pinter A, Puri P. Mucinous cystadenoma of the ovary in perimenarchal girls. Pediatr Surg Int. 2006;22:224-7 pubmed
    ..To the best of our knowledge, there are only 13 previous cases of benign mucinous cystadenoma (MCA) of the ovary in perimenarchal girls reported in the literature...
  13. Heiskala K, Giles Komar J, Heiskala M, Andersson L. High expression of RELP (Reg IV) in neoplastic goblet cells of appendiceal mucinous cystadenoma and pseudomyxoma peritonei. Virchows Arch. 2006;448:295-300 pubmed
    ..Our findings indicate that RELP serves as a marker for appendiceal mucinous cystadenomas and PMP, and that RELP may contribute to the pathogenesis of these disorders...
  14. Tang P, Soukkary S, Kahn E. Mature cystic teratoma of the ovary associated with complete colonic wall and mucinous cystadenoma. Ann Clin Lab Sci. 2003;33:465-70 pubmed
    ..The association of mature cystic teratoma with mucinous cystadenoma is not unusual. However, the pathogenetic relationship between these two lesions remains unanswered...
  15. Tamura T, Yamataka A, Murakami T, Okada Y, Kobayashi H, Ohshiro K, et al. Primary mucinous cystadenoma arising from behind the posterior peritoneum of the descending colon in a child: a case report. Asian J Surg. 2003;26:237-9 pubmed
    This is the first report of a primary mucinous cystadenoma (MCA) arising from behind the posterior peritoneum of the descending colon in a paediatric patient...
  16. Czubalski A, Barwijuk A, Radiukiewicz G. [Large mesenteric cyst in a patient suspected of ovarian cyst]. Ginekol Pol. 2004;75:545-7 pubmed
    ..The patient was operated on and we found that genital organs were normal. Besides there was a large cyst of small intestine mesentery with 10 liters of clear fluid. The cyst was removed. Histological material showed mucinous cystadenoma.
  17. Behranwala K, Agarwal T, El Sharkawi D, Shorvon D, Chang A. Laparoscopic resection of mucinous cystadenoma of appendix: a careful decision. Surg Laparosc Endosc Percutan Tech. 2006;16:347-8 pubmed
    ..Rupture of the lesion causes pseudomyxoma peritonei. We present a case to highlight this point and especially deplore the use of laparoscopy if the tumor clearly extends beyond the appendix...
  18. Matsuo T, Yusuke Kimura N, Takamori S, Shirouzu K. Recurrent pulmonary mucinous cystadenoma. Eur J Cardiothorac Surg. 2005;28:176-7 pubmed
    ..We report a case of a 56-year-old female who had recurrent pulmonary mucinous cystadenoma. She had previously received a partial resection of the lung for a pulmonary mucinous cystadenoma 20 years ..
  19. Rampone B, Roviello F, Marrelli D, Pinto E. Giant appendiceal mucocele: report of a case and brief review. World J Gastroenterol. 2005;11:4761-3 pubmed
    ..Surgery revealed a giant retro-cecal appendix measuring 17 cm in length and 4 cm in diameter. The final pathologic diagnosis was mucocele caused by mucinous cystadenoma.
  20. Djuranovic S, Spuran M, Kovacevic N, Ugljesic M, Kecmanovic D, Micev M. Mucinous cystadenoma of the appendix associated with adenocarcinoma of the sigmoid colon and hepatocellular carcinoma of the liver: report of a case. World J Gastroenterol. 2006;12:1975-7 pubmed
    b>Mucinous cystadenoma of the appendix is a rare condition and represents one of the three entities with the common name mucocele of the appendix. It is characterized by a cystic dilatation of the lumen with stasis of mucus inside it...
  21. Zagrodnik D, Rose D. Mucinous cystadenoma of the appendix: diagnosis, surgical management, and follow-up. Curr Surg. 2003;60:341-3 pubmed
    To review the diagnostic examination and clinical presentation of mucinous cystadenoma of the appendix.
  22. Casey R, Tan M, Salman R, Ryan J, Gillen P. Acute abdomen in pregnancy due to mucinous cystadenoma of the appendix. J Obstet Gynaecol. 2003;23:566-7 pubmed
  23. Linder J, Geenen J, Catalano M. Cyst fluid analysis obtained by EUS-guided FNA in the evaluation of discrete cystic neoplasms of the pancreas: a prospective single-center experience. Gastrointest Endosc. 2006;64:697-702 pubmed
    ..Reports involving EUS and cyst fluid analysis have been encouraging, including studies of EUS features and/or cyst fluid analysis, which may differentiate pancreatic cystic neoplasms...
  24. Sait K, Alkhattabi M, Alkushi A, Alqahtani M. Ovarian mucinous cystadenoma in a female with Turner syndrome. Saudi Med J. 2004;25:1270-3 pubmed
    ..Laparotomy and right oophorectomy were performed for the ovarian mass. Histology revealed a large mucinous cyst adenoma. Further study of these tumors may help to eludicate the underlying cause and pathogenesis...
  25. Ylisaukko Oja S, Cybulski C, Lehtonen R, Kiuru M, Matyjasik J, Szymanska A, et al. Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma. Eur J Hum Genet. 2006;14:880-3 pubmed
    ..Two patients diagnosed with ovarian mucinous cystadenoma (two out of 33, 6%) were found to be FH germline mutation carriers...
  26. Nunes Q, Wight N, Aithal G, Dunn W, Kaye P, Lobo D. Concurrent mucinous cystadenoma of the liver and bile duct: a rare cause of jaundice. Gastrointest Endosc. 2006;63:870-2 pubmed
  27. Bifulco G, Mandato V, Giampaolino P, Nappi C, De Cecio R, Insabato L, et al. Huge primary retroperitoneal mucinous cystadenoma of borderline malignancy mimicking an ovarian mass: case report and review. Anticancer Res. 2008;28:2309-15 pubmed
    Primary retroperitoneal mucinous cystadenoma is a rare tumor only 48 cases have been reported in international literature...
  28. Orta L, Trindade A, Luo J, Harpaz N. Appendiceal mucinous cystadenoma is a neoplastic complication of IBD: case-control study of primary appendiceal neoplasms. Inflamm Bowel Dis. 2009;15:415-21 pubmed publisher
    ..IBD is a risk factor for development of colorectal neoplasia. Although IBD frequently involves the appendix microscopically, it is uncertain whether it also predisposes to appendiceal neoplasia...
  29. Takashi M, Matsuyama M, Furuhashi K, Kodama Y, Shinzato M, Shamoto M, et al. Composite tumor of mucinous cystadenoma and somatostatinoma of the kidney. Int J Urol. 2003;10:603-6 pubmed
    ..From the histopathological findings we diagnosed the cystic lesion as a composite tumor composed of mucinous cystadenoma and carcinoid tumor...
  30. Malkan A, Braich P, Singh Braich P, Panait L, Dudrick S. Mucinous cystadenoma of the ovary presenting as unilateral lower extremity edema. Conn Med. 2009;73:517-9 pubmed
    ..They are typically benign tumors accounting for 15% of ovarian neoplasms and up to 80% of all mucinous tumors...
  31. Ulbright T, Young R. Primary mucinous tumors of the testis and paratestis: a report of nine cases. Am J Surg Pathol. 2003;27:1221-8 pubmed
    ..Clinical features are important to exclude metastasis, particularly in cases of carcinoma and, to a lesser extent, in tumors of borderline type...
  32. Gutsu E, Mishin I, Gagauz I. Primary retroperitoneal mucinous cystadenoma. A case report and brief review of the literature. Zentralbl Chir. 2003;128:691-3 pubmed
    ..An additional case of retroperitoneal mucinous cystadenoma histologically confirmed in a 41-year- old woman is reported herein...
  33. Zahn C, Kendall B. Heterotopic bone in the ovary associated with a mucinous cystadenoma. Mil Med. 2001;166:915-7 pubmed
    ..We report a case of bone formation within a mucinous cystadenoma of the ovary...
  34. Persaud T, Swan N, Torreggiani W. Giant mucinous cystadenoma of the appendix. Radiographics. 2007;27:553-7 pubmed
  35. Jeurnink S, Vleggaar F, Siersema P. Overview of the clinical problem: facts and current issues of mucinous cystic neoplasms of the pancreas. Dig Liver Dis. 2008;40:837-46 pubmed publisher
    ..Further research may lead to a definitive guideline for the diagnosis and treatment of mucinous cystic neoplasms, intraductal papillary mucinous neoplasms and serous cystic neoplasms...
  36. Nokubi M, Kawai T, Mitsu S, Ishikawa S, Morinaga S. Mucinous cystadenoma of the testis. Pathol Int. 2002;52:648-52 pubmed
    ..The tumor was diagnosed as mucinous cystadenoma of the testis...
  37. Abe H, Kimura W, Mori M, Makuuchi M, Yanagisawam A. Mixed serous cystadenoma with mucinous cystadenoma of the pancreas. Pancreas. 2005;31:98-100 pubmed
    We report a case of serous cystadenoma of the pancreas mixed with mucinous cystadenoma. A 65-year-old woman was admitted to our hospital for evaluation of a palpable, elastic, hard mass measuring 6 cm in diameter in the right upper ..
  38. Yamaguchi S, Fujii S, Ike H, Shimada H. Laparoscopic reduction of appendicocecal intussusception due to mucinous cystadenoma in an adult. JSLS. 2004;8:279-82 pubmed
    Laparoscopic reduction of appendicocecal intussusception due to mucinous cystadenoma is herein described.
  39. D Journo X, Moutardier V, Turrini O, Guiramand J, Lelong B, Pesenti C, et al. Gastric duplication in an adult mimicking mucinous cystadenoma of the pancreas. J Clin Pathol. 2004;57:1215-8 pubmed
    ..It is often difficult to discriminate GDC from pancreatic cystic tumour, in particular pancreatic mucinous cystadenoma, in which concentrations of carcinoembryonic antigen and CA 19-9 are classically raised...
  40. Giri S, Long R, Barry D, Flood H, Moran K. Ureteral endometriosis and ovarian mucinous cystadenoma presenting with acute pyonephrosis. Ir J Med Sci. 2005;174:67-70 pubmed
    ..Endometriosis is a common disease, but ureteral involvement is rare. Nonspecific clinical presentations of ureteral endometriosis may result in diagnostic difficulty...
  41. Matsubara M, Shiozawa T, Tachibana R, Hondo T, Osasda K, Kawaguchi K, et al. Primary retroperitoneal mucinous cystadenoma of borderline malignancy: a case report and review of the literature. Int J Gynecol Pathol. 2005;24:218-23 pubmed
    ..The histologic diagnosis was a primary retroperitoneal mucinous cystic tumor of borderline malignancy, similar to findings for ovarian tumor. There was no evidence of disease 6 months after the surgery...
  42. McKenna M, Kenny B, Dorman G, McCluggage W. Combined adult granulosa cell tumor and mucinous cystadenoma of the ovary: granulosa cell tumor with heterologous mucinous elements. Int J Gynecol Pathol. 2005;24:224-7 pubmed
    We describe an unusual ovarian neoplasm in a 57-year-old woman composed of an admixture of mucinous cystadenoma and adult granulosa cell tumor (AGCT)...
  43. Mittal S, Gupta N, Sharma A, Dadhwal V. Laparoscopic management of a large recurrent benign mucinous cystadenoma of the ovary. Arch Gynecol Obstet. 2008;277:379-80 pubmed publisher
    ..Laparoscopy has become an accepted method of management for ovarian cysts and its role is expanding as large benign adnexal masses more than 10 cm can be managed safely and effectively...
  44. Karaman A, Azili M, Boduroglu E, Karaman I, Erdogan D, Cavusoglu Y, et al. A huge ovarian mucinous cystadenoma in a 14-year-old premenarchal girl: review on ovarian mucinous tumor in premenarchal girls. J Pediatr Adolesc Gynecol. 2008;21:41-4 pubmed publisher
    ..b>Mucinous cystadenoma (MCA) in children that is a rare form of epithelial tumor is a benign cystic ovarian neoplasm...
  45. Hart W. Mucinous tumors of the ovary: a review. Int J Gynecol Pathol. 2005;24:4-25 pubmed
    ..Numerous immunohistochemical stains proposed to aid in the differential diagnosis of primary vs. secondary mucinous tumors also are reviewed...
  46. Yan S, Lin H, Kuo C, Wu H, Huang M, Lee Y. Primary retroperitoneal mucinous cystadenoma: Report of a case and review of the literature. World J Gastroenterol. 2008;14:5769-72 pubmed
    ..Histopathological examination of the resected mass confirmed the diagnosis of RMC. There was no evidence of disease 2 years after surgery...
  47. Rizzardi C, Brollo A, Thomann B, Santirocco C, Melato M. Intra-abdominal ovarian-type mucinous cystadenoma associated with fallopian tube-like structure and aberrant epididymal tissue in a male patient. Hum Pathol. 2005;36:927-31 pubmed
    ..We describe a unique case of an ovarian-type mucinous cystadenoma occurring in the peritoneal cavity of a 65-year-old male patient with secondary adrenocortical ..
  48. Wani Y, Notohara K. Ovarian clear cell carcinoma arising in a mucinous cystadenoma. Int J Gynecol Pathol. 2009;28:584-8 pubmed publisher
    Here we report a rare case of ovarian clear cell carcinoma (CC) arising in a mucinous cystadenoma. A 59-year-old woman presented with a dull pain at the left inguinal area. She was found to have a left ovarian cyst measuring 4...
  49. Utsunomiya D, Shiraishi S, Kawanaka K, Lwakatare F, Tomiguchi S, Kido R, et al. Struma ovarii coexisting with mucinous cystadenoma detected by radioactive iodine. Clin Nucl Med. 2003;28:725-7 pubmed
    The authors describe a case of struma ovarii coexisting with mucinous cystadenoma. Ultrasonography and magnetic resonance imaging showed a multilocular cystic mass with a solid component...
  50. Izumo A, Yamaguchi K, Eguchi T, Nishiyama K, Yamamoto H, Yonemasu H, et al. Mucinous cystic tumor of the pancreas: immunohistochemical assessment of "ovarian-type stroma". Oncol Rep. 2003;10:515-25 pubmed
    ..We therefore conclude there is a possibility that MCT-P originates from the left remnant primordial gonadal cells which migrated to the pancreatic anlage during the early development of the fetus...
  51. Nouri K, Demmel M, Ott J, Promberger R, Huber J, Mayerhofer K. Villous mucinous cystadenoma of the appendix in a postmenopausal woman. JSLS. 2010;14:296-8 pubmed publisher
    ..To present the case of a postmenopausal woman, who was suspected of having an ovarian cyst. Instead, a cystadenoma of the appendix was discovered during laparoscopy...
  52. Chiu C, Wei P, Huang M, Wang W, Chen T, Lee W. Laparoscopic resection of appendiceal mucinous cystadenoma. J Laparoendosc Adv Surg Tech A. 2005;15:325-8 pubmed
    b>Mucinous cystadenoma is a rare lesion of the vermiform appendix and is seldom diagnosed before surgery, although radiologic and ultrasonographic findings have been reported...
  53. Alobaid A. Mucinous cystadenoma of the ovary in a 12-year-old girl. Saudi Med J. 2008;29:126-8 pubmed
    ..The diagnosis of MCA should be considered in children who present with huge pelvi-abdominal masses. Early recognition and intervention are necessary to avoid potential complications...
  54. Bakker R, Stoot J, Blok P, Merkus J. Primary retroperitoneal mucinous cystadenoma with sarcoma-like mural nodule : a case report and review of the literature. Virchows Arch. 2007;451:853-7 pubmed
    ..Histologic examination showed a mucinous cystadenoma with only foci of borderline malignancy with a mural "sarcoma-like" nodule...