bile duct adenoma


Summary: A benign tumor of the intrahepatic bile ducts.

Top Publications

  1. Chang H, Chung J, Lee D, Kim K, Jang H. A limited polyarteritis nodosa of the liver and gallbladder accompanied with a solitary cystic dilatation of the intrahepatic bile duct. Clin Exp Rheumatol. 2003;21:525 pubmed
  2. Hasebe T, Sakamoto M, Mukai K, Kawano N, Konishi M, Ryu M, et al. Cholangiocarcinoma arising in bile duct adenoma with focal area of bile duct hamartoma. Virchows Arch. 1995;426:209-13 pubmed
    ..tumour in S4 showed a number of bile ductules with variable amounts of stroma, an appearance compatible with bile duct adenoma (BDA)...
  3. Albores Saavedra J, Hoang M, Murakata L, Sinkre P, Yaziji H. Atypical bile duct adenoma, clear cell type: a previously undescribed tumor of the liver. Am J Surg Pathol. 2001;25:956-60 pubmed
    ..One atypical bile duct adenoma displayed luminal immunoreactivity for villin...
  4. Aggarwal S, Kumar S, Kumar A, Bhasin R, Garg P, Bandhu S. Extra-hepatic bile duct adenoma in a patient with a choledochal cyst. J Gastroenterol Hepatol. 2003;18:351-2 pubmed
  5. Maeda E, Uozumi K, Kato N, Akahane M, Inoh S, Inoue Y, et al. Magnetic resonance findings of bile duct adenoma with calcification. Radiat Med. 2006;24:459-62 pubmed
    Computed tomographic (CT) and magnetic resonance (MR) appearances of bile duct adenoma (BDA in a patient who underwent partial hepatectomy of segment 8 are presented...
  6. Ohta T, Nagakawa T, Ueda N, Nakamura T, Akiyama T, Ueno K, et al. Mucosal dysplasia of the liver and the intraductal variant of peripheral cholangiocarcinoma in hepatolithiasis. Cancer. 1991;68:2217-23 pubmed
    ..The authors hypothesize that the lining epithelium of the large bile duct, when persistently exposed to biochemically altered bile, may undergo a carcinomatous transformation through a stage of mucosal dysplasia. ..
  7. Polydorou A, Cairns S, Dowsett J, Hatfield A, Salmon P, Cotton P, et al. Palliation of proximal malignant biliary obstruction by endoscopic endoprosthesis insertion. Gut. 1991;32:685-9 pubmed
    ..Second stents should be placed only if required. Extensive structuring because of metastatic disease carries a poor prognosis and careful patient selection for treatment is requires. ..
  8. Böckmann S, Bernhardt Huth D, Huth F, Fritsch W. [Metastatic bile duct cancer in secondary biliary cirrhosis associated with primary sclerosing cholangitis in ulcerative colitis]. Z Gastroenterol. 1990;28:363-7 pubmed
    ..The course was complicated by the development of a bile-duct carcinoma. Present possibilities of diagnosis and therapy are discussed. ..
  9. Traynor O, Castaing D, Bismuth H. Left intrahepatic cholangio-enteric anastomosis (round ligament approach): an effective palliative treatment for hilar cancers. Br J Surg. 1987;74:952-4 pubmed
    ..The mean survival was 9.2 months and the quality of life was excellent. These data suggest that this is a very satisfactory palliative technique for patients with hilar cancer who are not suited for radical tumour excision. ..

More Information

Publications114 found, 100 shown here

  1. Thamavit W, Moore M, Hiasa Y, Ito N. Enhancement of DHPN induced hepatocellular, cholangiocellular and pancreatic carcinogenesis by Opisthorchis viverrini infestation in Syrian golden hamsters. Carcinogenesis. 1988;9:1095-8 pubmed
  2. Epivatianos A, Trigonidis G. Salivary gland tumors studied by means of the AgNOR technique. Ann Dent. 1994;53:21-5 pubmed
  3. Arena V, Arena E, Stigliano E, Capelli A. Bile duct adenoma with oncocytic features. Histopathology. 2006;49:318-20 pubmed
  4. Wallner B, Edelman R, Mattle H. [Nuclear magnetic resonance tomography of the liver with Turbo FLASH]. Digitale Bilddiagn. 1990;10:86-91 pubmed
    ..63 +/- 0.18). On Turbo FLASH scans, there were no flow or motion artifacts and lesions borders and structures were better delineated than on the spin-echo images. Imaging time for the whole liver is less than a minute. ..
  5. Nagata Y, Hiraoka M, Akuta K, Abe M, Takahashi M, Jo S, et al. Radiofrequency thermotherapy for malignant liver tumors. Cancer. 1990;65:1730-6 pubmed
    ..No apparent relationship was observed between the intratumor temperatures and local response rate. ..
  6. Tio T, Wijers O, Sars P, Tytgat G. Preoperative TNM classification of proximal extrahepatic bile duct carcinoma by endosonography. Semin Liver Dis. 1990;10:114-20 pubmed
    ..Technical improvements, such as reduction of the diameter of the echoprobe, easy handling of ES-guided cytologic puncture, and the routine use of a catheter echoprobe during ERCP will further enhance the accuracy of ES. ..
  7. Richardson A, Grierson J, Tait N, Williams S, Little J. A case of cholangitis glandularis proliferans and cholangiocarcinoma of the common bile duct. HPB Surg. 1993;6:205-9 pubmed
    ..A case of Cholangitis Glandularis Proliferans (CAGP) in association with a cholangiocarcinoma of the common bile duct as described. This is the eighth case of CAGP described and the second association with cholangiocarcinoma. ..
  8. Vatanasapt V, Tangvoraphonkchai V, Titapant V, Pipitgool V, Viriyapap D, Sriamporn S. A high incidence of liver cancer in Khon Kaen Province, Thailand. Southeast Asian J Trop Med Public Health. 1990;21:489-94 pubmed
    ..The observed geographical clusters of liver cancer appear to be associated with the prevalence and intensity of Opisthorchis viverrini infection, as reported in previous studies in this area. ..
  9. Ferrandez Izquierdo A, Llombart Bosch A. Immunohistochemical characterization of 130 cases of primary hepatic carcinomas. Pathol Res Pract. 1987;182:783-91 pubmed
    ..Therefore the present results confirm that in the geographical area from which these tumors proceed, PLC is closely correlated with HBsAg positivity and with cirrhosis. ..
  10. Vick D, Goodman Z, Deavers M, Cain J, Ishak K. Ciliated hepatic foregut cyst: a study of six cases and review of the literature. Am J Surg Pathol. 1999;23:671-7 pubmed
    ..CHFC should be considered in the differential diagnosis of other solitary liver cysts, including simple cysts, hepatobiliary cystadenomas, and parasitic cysts. ..
  11. Tsuda H, Satarug S, Bhudhisawasdi V, Kihana T, Sugimura T, Hirohashi S. Cholangiocarcinomas in Japanese and Thai patients: difference in etiology and incidence of point mutation of the c-Ki-ras proto-oncogene. Mol Carcinog. 1992;6:266-9 pubmed
    ..On the other hand, point-mutational activation of the c-Ki-ras proto-oncogene may be involved in cholangiocarcinogenesis in liver without preexisting liver-fluke or viral infection. ..
  12. Paivansalo M, Tikkakoski T, Typpö T, Kallioinen M. Radiological findings in primary liver malignancies. Rofo. 1991;154:131-8 pubmed
    ..In the group of tumours of diameter less than 8 cm, US missed 5%, CT 15%, arteriography 9% and scintigraphy 22%. In tumours 8 cm or larger US missed 4%, CT 0%, arteriography 5% and scintigraphy 18%. ..
  13. Kedar R, Malde H. Biliary ascariasis associated with cholangiocarcinoma. Abdom Imaging. 1993;18:76-7 pubmed
    ..A localized mass projecting into the common bile duct and causing its obstruction proved to be a coexistent cholangiocarcinoma. ..
  14. Capizzi P, Rosen C, Nagorney D. Intermittent jaundice by tumor emboli from intrahepatic cholangiocarcinoma. Gastroenterology. 1992;103:1669-73 pubmed
  15. Aburano T, Taniguchi M, Hisada K, Miyazaki Y, Kakuma K, Fujioka M. Discordant hepatic uptake of Tc-99m HIDA and Tc-99m colloid in a patient with segmental biliary obstruction. Clin Nucl Med. 1988;13:599-601 pubmed
    ..At surgery this was confirmed, and a 2 cm mass encasing the right hepatic duct was identified. It should be included in the gamut of discordant hepatic uptake of Tc-99m IDA and Tc-99m colloid...
  16. Sheen Chen S, Chou F, Eng H. Intrahepatic cholangiocarcinoma in hepatolithiasis: A frequently overlooked disease. J Surg Oncol. 1991;47:131-5 pubmed
  17. Neuhaus H, Hagenmuller F, Griebel M, Classen M. Percutaneous cholangioscopic or transpapillary insertion of self-expanding biliary metal stents. Gastrointest Endosc. 1991;37:31-7 pubmed
    ..In patients with malignant stenoses, the probability of stent patency is 78% after 200 days. We conclude that large-bore metal stents are safe, effective, and provide better long-term patency than conventional endoprostheses. ..
  18. Verbeek P, van der Heyde M, Ramsoekh T, Bosma A. Clinical significance of implantation metastases after surgical treatment of cholangiocarcinoma. Semin Liver Dis. 1990;10:142-4 pubmed
    ..A relation between tumor-positive bile cytologic findings, tumor spill, and seeding during surgery is likely to exist. It is recommended that during surgery the utmost care should be taken to prevent spill of bile. ..
  19. Subramony C, Herrera G, Turbat Herrera E. Hepatobiliary cystadenoma. A study of five cases with reference to histogenesis. Arch Pathol Lab Med. 1993;117:1036-42 pubmed
    ..This study supports the hypothesis that the hepatobiliary cystadenomas arise from ectopic embryonic tissues destined to form the adult gallbladder. ..
  20. Lameris J, Hesselink E, van Leeuwen P, Nijs H, Meerwaldt J, Terpstra O. Ultrasound-guided percutaneous transhepatic cholangiography and drainage in patients with hilar cholangiocarcinoma. Semin Liver Dis. 1990;10:121-5 pubmed
    ..The median survival of patients treated with PTCD alone only was 4 months. A significant increase in survival was noted in patients treated with PTCD and radiotherapy (median survival 8 months).(ABSTRACT TRUNCATED AT 250 WORDS) ..
  21. Marleen P, Hendrik R, Van Oostveldt P. Early liver cell lesions in rats induced by thioacetamide. An ultrastructural, cytophotometric and autoradiographic study. Pathol Res Pract. 1988;184:69-76 pubmed
    ..This is the first study reporting oval cell proliferation in the centrolobular area in a multistep model of livercarcinogenesis in rats. ..
  22. Schumacher G, Bechstein W, Kling N, Lobeck H, Hintze R, Neuhaus P. [Bile duct carcinoma in an adenoma in the anastomotic area after hepaticojejunostomy--a case report]. Z Gastroenterol. 1997;35:1081-6 pubmed
    ..Because of the heterogeneity inside the lesions a malignant lesion can only be excluded by histopathological examination of the whole tumor. ..
  23. Ignee A, Piscaglia F, Ott M, Salvatore V, Dietrich C. A benign tumour of the liver mimicking malignant liver disease--cholangiocellular adenoma. Scand J Gastroenterol. 2009;44:633-6 pubmed publisher
    ..malignant tumours diagnosed finally, using contrast-enhanced ultrasound, as cholangiocellular adenoma (bile duct adenoma). Focal liver lesions found incidentally in three patients...
  24. Fukuda M, Hirata K, Mima S. Preliminary evaluation of sonolaparoscopy in the diagnosis of liver diseases. Endoscopy. 1992;24:701-8 pubmed
    ..Sonolaparoscopy was shown to be particularly suitable for detection and differentiation of occult liver lesions, cysts, tumors, various benign focal hyperplasias and various granulomata. ..
  25. Balaton A, Nehama Sibony M, Gotheil C, Callard P, Baviera E. Distinction between hepatocellular carcinoma, cholangiocarcinoma, and metastatic carcinoma based on immunohistochemical staining for carcinoembryonic antigen and for cytokeratin 19 on paraffin sections. J Pathol. 1988;156:305-10 pubmed
    ..All the hepatocellular carcinomas were negative for CK 19. All the cholangiocellular carcinomas and the metastatic carcinomas were positive for CK 19. This staining profile may prove helpful in difficult diagnostic cases. ..
  26. James J, Lygidakis N, Van Eyken P, Tanka A, Bosch K, Ramaekers F, et al. Application of keratin immunocytochemistry and sirius red staining in evaluating intrahepatic changes with acute extrahepatic cholestasis due to hepatic duct carcinoma. Hepatogastroenterology. 1989;36:151-5 pubmed
    ..Development of fibrosis, not always strictly paralleling the multiplication of ductular profiles in sections through a portal tract, represents an early change, and is clearly apparent after 2 weeks of obstruction. ..
  27. Puleo S, Di Carlo I, Trombatore G, Ciraldo R, Rodolico M, Greco L, et al. [Benign tumors of the liver]. Minerva Chir. 1993;48:589-94 pubmed
    ..Diagnostic and therapeutic findings of benign hepatic tumors are analysed. In particularly the authors describe the more frequent tumors such as angioma, adenoma and FNH, but also give a guidelines on how to approach less frequent lesions. ..
  28. Cullen J, Sandgren E, Brinster R, Maronpot R. Histologic characterization of hepatic carcinogenesis in transgenic mice expressing SV40 T-antigens. Vet Pathol. 1993;30:111-8 pubmed
    ..Subcutaneous trabecular hepatocellular carcinomas developed in two of three syngeneic mice that had received transplants of a solid hepatic neoplasm, confirming the neoplastic behavior of these tumors.(ABSTRACT TRUNCATED AT 250 WORDS) ..
  29. Ding S, Delhanty J, Bowles L, Dooley J, Wood C, Habib N. Loss of constitutional heterozygosity on chromosomes 5 and 17 in cholangiocarcinoma. Br J Cancer. 1993;67:1007-10 pubmed
    ..Probes for other chromosomes have as yet shown no consistent LOH. In conclusion, this study for the first time showed LOH on chromosomes 5 and 17 in cholangiocarcinoma. ..
  30. Maronpot R, Giles H, Dykes D, Irwin R. Furan-induced hepatic cholangiocarcinomas in Fischer 344 rats. Toxicol Pathol. 1991;19:561-70 pubmed
  31. Kiuchi T, Ozawa K, Takada Y, Yamaguchi T, Shimahara Y, Mori K, et al. Increased arterial ketone body ratio as a prerequisite for recovery after hepatectomy. Hepatogastroenterology. 1993;40:253-8 pubmed
    ..It is suggested that the recovery of hepatic mitochondrial redox state is also a prerequisite in partial hepatectomy, where a reduced and often damaged liver confronts systemic metabolic load. ..
  32. Kurashina M, Kozuka S, Nakasima N, Hirabayasi N, Ito M. Relationship of intrahepatic bile duct hyperplasia to cholangiocellular carcinoma. Cancer. 1988;61:2469-74 pubmed
    ..All 27 cases of cholangiocellular carcinoma originated in, or near, the hilus of the liver. These findings suggest that cholangiocellular carcinoma frequently develops from bile duct hyperplasia. ..
  33. Martinez Isla A, Rouco Rouco J, Mosquera Luengo J. [Biliary cystadenoma]. Rev Esp Enferm Dig. 1996;88:634-6 pubmed
    ..Total excision by shelling out the lesion from the liver parenchyma was performed. We recommend complete surgical removal as the treatment of choice due to the malignant potential and the high recurrence rate after partial resections. ..
  34. Nakajima T, Kubosawa H, Kondo Y, Konno A, Iwama S. Combined hepatocellular-cholangiocarcinoma with variable sarcomatous transformation. Am J Clin Pathol. 1988;90:309-12 pubmed
    ..On the basis of these findings, the possibility of sarcomatous transformation of combined hepatocellular-cholangiocarcinoma was discussed. ..
  35. Bengmark S, Ekberg H, Evander A, Klofver Stahl B, Tranberg K. Major liver resection for hilar cholangiocarcinoma. Ann Surg. 1988;207:120-5 pubmed
    ..The importance of a free resection margin indicates that surgery should be aggressive and include liver resection. ..
  36. Davies W, Chow M, Nagorney D. Extrahepatic biliary cystadenomas and cystadenocarcinoma. Report of seven cases and review of the literature. Ann Surg. 1995;222:619-25 pubmed
    ..The aim of this investigation was to describe the clinical features, diagnosis, pathologic characteristics, and optimal surgical management for patients with extrahepatic biliary cystadenomas...
  37. Desa L, Akosa A, Lazzara S, Domizio P, Krausz T, Benjamin I. Cytodiagnosis in the management of extrahepatic biliary stricture. Gut. 1991;32:1188-91 pubmed
  38. Hall R, Denyer M, Chapman A. Percutaneous-endoscopic placement of endoprostheses for relief of jaundice caused by inoperable bile duct strictures. Surgery. 1990;107:224-7 pubmed
    ..The combined percutaneous-endoscopic technique enables difficult biliary strictures to be intubated. Although bilateral duct drainage is preferable, the palliation is often worthwhile even when segmental ducts alone are drained. ..
  39. Motoo Y, Sawabu N, Minamoto T, Kawakami H, Ohta H, Okai T, et al. Rapidly growing mucinous cholangiocarcinoma. Intern Med. 1993;32:116-21 pubmed
  40. Elangbam C, Panciera R. Cholangiocarcinoma in a blue-fronted Amazon parrot (Amazona estiva). Avian Dis. 1988;32:594-6 pubmed
    ..The only other reported cases of cholangiocarcinoma in an Amazon parrot (Amazona xanthops) also occurred in a bird in its fourth year of age...
  41. Kinami Y, Ashida Y, Seto K, Takashima S, Kita I. The effect of incomplete bile duct obstruction on diisopropanolnitrosamine-induced cholangiocarcinoma. HPB Surg. 1991;3:117-25; discussion 125-7 pubmed
    ..These results suggest that IBDO has an influence, as promoter, on the occurrence of cholangiocarcinoma induced by DIPN, and the disappearance of its promoting effect is caused by release of the obstruction. ..
  42. Tada M, Omata M, Ohto M. Analysis of ras gene mutations in human hepatic malignant tumors by polymerase chain reaction and direct sequencing. Cancer Res. 1990;50:1121-4 pubmed
    ..These observations suggest that ras gene mutations are not related to pathogenesis of hepatocellular carcinoma, but play an important role in pathogenesis of cholangiocarcinoma. ..
  43. Cariani E, Seurin D, Lasserre C, Franco D, Binoux M, Brechot C. Expression of insulin-like growth factor II (IGF-II) in human primary liver cancer: mRNA and protein analysis. J Hepatol. 1990;11:226-31 pubmed
    ..This finding is consistent with IGF-II being a marker of liver cell differentiation. In addition, this growth factor might be involved in liver cancer progression by an autocrine and/or paracrine mechanism. ..
  44. Lee H, Yoon J, Kim H, Yi N, Hong S, Yoon K, et al. False Positive Diagnosis of Hepatocellular Carcinoma in Liver Resection Patients. J Korean Med Sci. 2017;32:315-320 pubmed publisher
    ..conditions (one each of hemangioma, inflammation, cortical adenoma, dysplastic nodule, angiomyolipoma, bile duct adenoma, and non-neoplastic liver parenchyme) and 11 patients (1...
  45. Kapoor R, Calton N, Verghese M. Cystadenoma with mesenchymal stroma mistaken for hepatic hydatid cyst. Indian J Gastroenterol. 1997;16:73-4 pubmed
    ..We describe a case of hepatobiliary cystadenoma with mesenchymal stroma which was initially treated as hepatic hydatid cyst. ..
  46. Terada T, Nakanuma Y, Ohta T, Nagakawa T. Histological features and interphase nucleolar organizer regions in hyperplastic, dysplastic and neoplastic epithelium of intrahepatic bile ducts in hepatolithiasis. Histopathology. 1992;21:233-40 pubmed
  47. Nonomura A, Ohta G, Nakanuma Y, Izumi R, Mizukami Y, Matsubara F, et al. Simultaneous detection of epidermal growth factor receptor (EGF-R), epidermal growth factor (EGF) and ras p21 in cholangiocarcinoma by an immunocytochemical method. Liver. 1988;8:157-66 pubmed
    ..Furthermore, the data also indicate that an autocrine model for tumor growth, as suggested by a combination of EGF and EGF-R, may be applicable only to very limited cases of CCs. ..
  48. Leitha T, Stumpflen A, Gebauer A, Amann G, Dudczak R. "False positive" immunoscintigraphic diagnosis of liver abscesses in a patient with a necrotic liver tumour. Eur J Nucl Med. 1989;15:673-5 pubmed
  49. Anderson W, Dougherty E, Steinberg H. Cholangiocarcinoma in a 4-month-old double yellow-cheeked Amazon parrot (Amazona autumnalis). Avian Dis. 1989;33:594-9 pubmed
    ..Elongated single cilia arising from basal bodies in the apical cytoplasm were occasionally evident. The presence of such a neoplasm in a 4-month-old parrot is extremely unusual...
  50. Lygidakis N, van der Heyde M, Verbeek P, van Leeuwen D. Technical considerations for the management of primary cholangiocarcinoma of the porta hepatis. Semin Liver Dis. 1990;10:126-30 pubmed
    ..The various technical options regarding these alternatives have been described in detail in this article...
  51. Uehara S, Hirano F, Sakai N, Honjo K, Hirayama A, Moriya H. [A case of cholangiocarcinoma with marked reduction of tumor after oral administration of UFT]. Gan To Kagaku Ryoho. 1989;16:411-4 pubmed
    ..The patient continues to be monitored as an outpatient. A marked reduction in the size of a cholangiocarcinoma was observed in the case, and administration of UFT has proved effective in prolonging life for over two years...
  52. Oyamada H, Yamazaki S, Makuuchi M, Hasegawa H. Clinical significance of 99mTc-N-pyridoxyl-5-methyltryptophan (99mTc-PMT) in the diagnosis of intrahepatic masses. Radioisotopes. 1989;38:244-51 pubmed
    ..However, both masses were strongly positive with 99mTc-PMT. 99mTc-PMT scintigraphy is useful in connection with 99mTc-colloid scan and sometimes with 67Ga-citrate in the diagnosis of intrahepatic masses originating from hepatocytes...
  53. Ohta T, Nagakawa T, Konishi I, Ueno K, Kanno M, Akiyama T, et al. Clinical experience of intrahepatic cholangiocarcinoma associated with hepatolithiasis. Jpn J Surg. 1988;18:47-53 pubmed
    Between 1960 and 1986, seven patients with intrahepatic cholangiocarcinoma and one patient with intrahepatic bile duct adenoma, related to hepatolithiasis, were seen among 112 cases of hepatolithiasis...
  54. Yeung E, McCarthy P, Gompertz R, Benjamin S, Gibson R, Dawson P. The ultrasonographic appearances of hilar cholangiocarcinoma (Klatskin tumours). Br J Radiol. 1988;61:991-5 pubmed
    ..The mass detection rate of different ultrasound equipment was also compared. In 15 patients the ability of ultrasound to predict the order of intrahepatic bile duct involvement was compared with cholangiography...
  55. Lee J, Rim H, Bak U. Effect of Clonorchis sinensis infection and dimethylnitrosamine administration on the induction of cholangiocarcinoma in Syrian golden hamsters. Korean J Parasitol. 1993;31:21-30 pubmed
    ..It was suggested that C. sinensis infection and DMN administration could be a synergism on the development of cholangiocarcinoma in Syrian golden hamsters...
  56. Izumi R, Shimizu K, Kiriyama M, Hashimoto T, Yagi M, Yamaguchi A, et al. Hepatic resection guided by needles inserted under ultrasonographic guidance. Surgery. 1993;114:497-501 pubmed
    ..We have devised a new technique for hepatectomy guided by needles inserted under ultrasonographic guidance...
  57. Nishikawa A, Furukawa F, Lee I, Kasahara K, Tanakamaru Z, Nakamura H, et al. Promoting effects of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone on rat glandular stomach carcinogenesis initiated with N-methyl-N'-nitro-N-nitrosoguanidine. Cancer Res. 1999;59:2045-9 pubmed
    ..The results of the present study thus indicate that MX exerts promoting effects when given during the postinitiation phase of two-stage glandular stomach carcinogenesis in rats...
  58. Nimura Y, Hayakawa N, Kamiya J, Maeda S, Kondo S, Yasui A, et al. Hepatopancreatoduodenectomy for advanced carcinoma of the biliary tract. Hepatogastroenterology. 1991;38:170-5 pubmed
    ..The longest survivor died of recurrent tumors at 5 years and 7 months. Hepatopancreatoduodenectomy offered not only an unexpectedly long survival period, but also unexpected morbidity in some cases...
  59. Boender J, Nix G, Schutte H, Lameris J, van Blankenstein M, Dees J. Malignant common bile duct obstruction: factors influencing the success rate of endoscopic drainage. Endoscopy. 1990;22:259-62 pubmed
  60. Koyama K, Tanaka J, Kato S, Asanuma Y. New strategy for treatment of carcinoma of the hilar bile duct. Surg Gynecol Obstet. 1989;168:523-30 pubmed
    ..Seven patients have been treated using this regimen. Follow-up study ranged from seven to 38 months. All patients are alive, and five of seven are disease-free...
  61. Palmer J, Rosenberg L, Kaufman D, Warshauer M, Stolley P, Shapiro S. Oral contraceptive use and liver cancer. Am J Epidemiol. 1989;130:878-82 pubmed
    ..However, the number of cases of liver cancer in the United States that are attributable to oral contraceptive use is probably small, because liver cancer is extremely rare in the United States...
  62. Itai Y, Ohtomo K, Kokubo T, Yoshida H, Minami M, Kawauchi N, et al. Diagnosis of coexistent hepatic tumors of different kinds: a challenge from CT and MR imaging. Radiat Med. 1989;7:143-9 pubmed
    ..CT and MR imaging may enable correct diagnosis to be made even in patients with multiple liver tumors of different kinds...
  63. Sasaki R. [Immunohistochemical study of cancer-associated carbohydrate antigens in carcinoma of the biliary tract]. Nihon Geka Gakkai Zasshi. 1989;90:1976-88 pubmed
    ..None of the antigens were stained in normal gallbladders. These results suggest that these antigens may be useful in the diagnosis and therapeutic treatments in patients with biliary tract cancer...
  64. Chou C, Liu G, Chen L, Jaw T. MRI manifestations of peritoneal carcinomatosis. Gastrointest Radiol. 1992;17:336-8 pubmed
    ..Ascites was present in all cases. One case showed ascites located only along the left paracolic gutter. This report shows that MRI is also able to demonstrate peritoneal carcinomatosis by using air as a gastrointestinal contrast medium...
  65. Kamei T, Futatsuya R, Seto H, Soya T, Kakishita M, Tsukishiro T, et al. A case of liver echinococcosis mimicing a solid liver tumor. Radiat Med. 1991;9:101-4 pubmed
    ..When a solid tumor is noted in the liver, proper history taking and awareness of this disease will decrease the chance of misdiagnosis...
  66. Heuschen U, Hofmann W, Otto H, Schlag P, Herfarth C. Clinico-pathological features and surgical management of primary epithelial hepatic malignancies. Eur J Surg Oncol. 1990;16:332-45 pubmed
    ..Long-term survival rates after curative resection were 78%, 55% and 21% for 1, 3, and 5 years, respectively. Prognostic factors of long-term survival were investigated by the Kaplan-Meier method...
  67. Frederiks W, Schellens J, Marx F, Vreeling Sindelárová H, Lygidakis N. The effect of internal biliary drainage on bile pigment accumulation and acid phosphatase activity in human liver during obstructive jaundice. Hepatogastroenterology. 1991;38:39-44 pubmed
    ..The co-localization of accumulations of bile compounds and acid phosphatase activity indicates that lysosomes play a role in the breakdown of bile compounds...
  68. Ismail T, Angrisani L, Gunson B, Hubscher S, Buckels J, Neuberger J, et al. Primary hepatic malignancy: the role of liver transplantation. Br J Surg. 1990;77:983-7 pubmed
    ..For those presenting with advanced disease confined to the liver (stage I/II) in whom conventional hepatic resection is not possible, significant benefit can be achieved in selected cases...
  69. Chen M, Jan Y, Wang C, Jeng L, Hwang T. Clinical experience in 20 hepatic resections for peripheral cholangiocarcinoma. Cancer. 1989;64:2226-32 pubmed
    ..Postoperative wound infection was the most common complication. The overall mean survival time was 20.5 months. Four patients survived for more than 3 years; one was even alive for more than 5 years after surgery...
  70. Ong E, Evans S, Hanley S. Pulmonary vasculitis associated with cholangiocarcinoma of liver. Postgrad Med J. 1989;65:791-3 pubmed
    ..Investigations over one year revealed a cholangiocarcinoma of the liver. The association of vasculitis with neoplastic diseases remains a diagnostic challenge...
  71. Boorman G, Botts S, Bunton T, Fournie J, Harshbarger J, Hawkins W, et al. Diagnostic criteria for degenerative, inflammatory, proliferative nonneoplastic and neoplastic liver lesions in medaka (Oryzias latipes): consensus of a National Toxicology Program Pathology Working Group. Toxicol Pathol. 1997;25:202-10 pubmed
  72. Pungpak S, Akai P, Longenecker B, Ho M, Befus A, Bunnag D. Tumour markers in the detection of opisthorchiasis-associated cholangiocarcinoma. Trans R Soc Trop Med Hyg. 1991;85:277-9 pubmed
    ..7% and 98.1% respectively. These preliminary results suggest that the measurement of CA125 and CA19-9 may be useful in the early detection of opisthorchiasis-associated cholangiocarcinoma...
  73. Srivatanakul P, Parkin D, Jiang Y, Khlat M, Kao Ian U, Sontipong S, et al. The role of infection by Opisthorchis viverrini, hepatitis B virus, and aflatoxin exposure in the etiology of liver cancer in Thailand. A correlation study. Cancer. 1991;68:2411-7 pubmed
  74. Yu Y, Tang Z, Ma Z, Zhou X, Lu J. Resection of the primary liver cancer of the hepatic hilus. Cancer. 1991;67:1322-5 pubmed
    ..9%, 43.2%, and 39.2% in the central type of PLC; they were 98.3%, 85.0%, and 76.4% in the peripheral type of PLC (P less than 0.001). Further discussion of improvements in surgical techniques and mental awareness are suggested...
  75. Foutch P, Kerr D, Harlan J, Manne R, Kummet T, Sanowski R. Endoscopic retrograde wire-guided brush cytology for diagnosis of patients with malignant obstruction of the bile duct. Am J Gastroenterol. 1990;85:791-5 pubmed
    ..A positive result is sufficient evidence for malignancy, and other invasive diagnostic tests are unnecessary. We recommend ERWBC for brushing all strictures of unknown cause during ERCP in an effort to make a diagnosis of cancer...
  76. Murphy J, Shay S, Moses F, Braxton J, Jaques D, Wong R. Suture granuloma masquerading as malignancy of the biliary tract. Dig Dis Sci. 1990;35:1176-9 pubmed
    ..At surgical exploration, the patient was found to have a suture granuloma with surrounding fibrosis within the common bile duct. There was no evidence of malignancy...
  77. Maruyama T, Koura Y, Kurisu Y, Kuroi K, Kai Y. [Intra-arterial infusion chemotherapy in non-resectable pancreatic cancer using angiotensin-II and implantable drug delivery system]. Gan To Kagaku Ryoho. 1989;16:2735-9 pubmed
    ..Quality of life has been improved, and course observation of the patient has been possible by imaging diagnosis and multidisciplinary treatment for advanced pancreatic cancer...
  78. Minato H, Nakanuma Y. Cell kinetic and morphological studies of human cholangiocellular carcinoma. Acta Pathol Jpn. 1993;43:111-20 pubmed
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    ..The finding that the expression of amylase isoenzymes was correlated with the histologic differentiation in CCC supports this suggestion...
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    ..Thus, both intraarterial and intraportal chemotherapy combined with decollateralization by silicone rubber sheeting seems to be effective for advanced cholangiocarcinoma and metastatic carcinoma...
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