endocrine gland neoplasms

Summary

Summary: Tumors or cancer of the ENDOCRINE GLANDS.

Top Publications

  1. Roche A, Girish B, de Baere T, Ducreux M, Elias D, Laplanche A, et al. Prognostic factors for chemoembolization in liver metastasis from endocrine tumors. Hepatogastroenterology. 2004;51:1751-6 pubmed
    ..The aims of this study were to assess response rates, evaluate side effects and determine prognostic factors for both response and toxicity in patients with liver metastasis from endocrine tumors treated with chemoembolization...
  2. Cecconi D, Donadelli M, Rinalducci S, Zolla L, Scupoli M, Scarpa A, et al. Proteomic analysis of pancreatic endocrine tumor cell lines treated with the histone deacetylase inhibitor trichostatin A. Proteomics. 2007;7:1644-53 pubmed
    ..et al.., Electrophoresis 2003; Cecconi, D. et al., J. Proteome Res. 2005) and place histone-deacetylases inhibitors among the potentially most powerful drugs for the treatment of pancreatic tumors...
  3. Marrache F, Cazals Hatem D, Kianmanesh R, Palazzo L, Couvelard A, O Toole D, et al. Endocrine tumor and intraductal papillary mucinous neoplasm of the pancreas: a fortuitous association?. Pancreas. 2005;31:79-83 pubmed
    ..The aim of this report is to describe a series of 6 patients with an original association of IPMN and PET of the pancreas...
  4. Ohike N, Kosmahl M, Kloppel G. Mixed acinar-endocrine carcinoma of the pancreas. A clinicopathological study and comparison with acinar-cell carcinoma. Virchows Arch. 2004;445:231-5 pubmed
    ..The frequent identification of endocrine cells in these tumors suggests the existence of a pluripotent cell of origin that is capable of differentiating into acinar and endocrine cells...
  5. Lansdown A, Rees D. Endocrine oncology in pregnancy. Best Pract Res Clin Endocrinol Metab. 2011;25:911-26 pubmed publisher
    ..Medical therapy may be required to reduce the drive to tumour growth, control symptoms of hormone excess and to minimise the risks of surgery, anaesthesia or labour...
  6. Bökenkamp R, Duchateau C, Stokkel M. An endocrine active insulinoma with extended lymphogenic dissemination. Clin Nucl Med. 2003;28:316-7 pubmed
  7. Cadiot G, Baudin E, Partensky C, Ruszniewski P, Ruzniewski P. Digestive endocrine tumors. Gastroenterol Clin Biol. 2006;30 Spec No 2:2S91-2S97 pubmed
  8. Suresh P, Venkatesh T, Tsutsumi R, Shetty A. Next-generation sequencing for endocrine cancers: Recent advances and challenges. Tumour Biol. 2017;39:1010428317698376 pubmed publisher
    ..We focus on recent discoveries in the use of next-generation sequencing methods for clinical diagnosis of endocrine tumors in patients and conclude with a discussion on persisting challenges and future objectives...
  9. Ouaissi M, Julie C, Mitry E, Sielezneff I, Jimenez P, Loundou A, et al. Prognostic factor of recurrence for resected digestive endocrine tumors. Hepatogastroenterology. 2009;56:1183-9 pubmed
    ..The aim of the present study was to identify the factors of recurrence for digestive endocrine tumours resected with curative intent...

More Information

Publications62

  1. Raitila A, Georgitsi M, Karhu A, Tuppurainen K, Mäkinen M, Birkenkamp Demtroder K, et al. No evidence of somatic aryl hydrocarbon receptor interacting protein mutations in sporadic endocrine neoplasia. Endocr Relat Cancer. 2007;14:901-6 pubmed
    ..The data also support the previous finding that somatic AIP mutations are not common in pituitary adenomas and suggest that such mutations are rare in other endocrine tumors as well...
  2. Lee Y, Asa S, Drucker D. Glucagon gene 5'-flanking sequences direct expression of simian virus 40 large T antigen to the intestine, producing carcinoma of the large bowel in transgenic mice. J Biol Chem. 1992;267:10705-8 pubmed
    ..The results of these studies provide functional evidence for the existence of an upstream cis-acting regulatory domain that directs glucagon gene transcription to the endocrine cells of the intestine in transgenic mice...
  3. Bachelot A, Meduri G, Baudin E, Kuttenn F, Touraine P. Hyperandrogenism in a postmenopausal woman presenting with a metastatic ileum endocrine tumor. Fertil Steril. 2004;81:675-8 pubmed
    ..To elucidate the mechanism of the hyperandrogenism found in a postmenopausal woman presenting an ileum endocrine tumor with ovarian metastases...
  4. Dimaline R, Campbell B, Watson F, Sandvik A, Struthers J, Noble P. Regulated expression of GATA-6 transcription factor in gastric endocrine cells. Gastroenterology. 1997;112:1559-67 pubmed
    ..The aim of this study was to determine if GATA factors are located in gastric endocrine cells and to examine their expression during development and in response to changes in the gastric luminal environment...
  5. Bombardieri E, Maccauro M, Castellani M, Chiti A, Procopio G, Bajetta E, et al. [Radioisotopic imaging of neuroendocrine tumours. Which radiopharmaceutical and which diagnostic procedure?]. Minerva Endocrinol. 2001;26:197-213 pubmed
    ..Aim of this review is to summarize the potential of nuclear medicine techniques in the diagnosis of neuroendocrine tumours and to stresses the renewed role of nuclear medicine in the management of this disease...
  6. Hervieu V, Poncet G, Valette P, Partensky C, Scoazec J. [Endocrine carcinoma of the pancreas revealed by a pseudocyst]. Ann Pathol. 2002;22:401-5 pubmed
    ..In most cases, the lesion corresponds to a misdiagnosed cystic tumor. Even if the lesion actually corresponds to a pseudocyst, as in the present case, an unusual cause, and particularly, an obstructive tumor, must be searched for...
  7. Garcia de la Torre N, Wass J, Turner H. Antiangiogenic effects of somatostatin analogues. Clin Endocrinol (Oxf). 2002;57:425-41 pubmed
  8. Hochwald S, Zee S, Conlon K, Colleoni R, Louie O, Brennan M, et al. Prognostic factors in pancreatic endocrine neoplasms: an analysis of 136 cases with a proposal for low-grade and intermediate-grade groups. J Clin Oncol. 2002;20:2633-42 pubmed
    ..The purpose of this study was to evaluate prognostic factors in pancreatic endocrine neoplasms recently treated at a single institution...
  9. Goretzki P, Wirowski D, Schwarz K, Pohl P, Bohner H, Starke A, et al. [Indication and performance of endocrine surgery. The significance of molecular genetic examination]. Chirurg. 2009;80:122-9 pubmed publisher
  10. Chatelain D, Mokrani N, Flejou J. [Anal and anal margin tumors]. Ann Pathol. 2007;27:459-75 pubmed publisher
    ..Cancers are infrequent and consisted of well-differentiated squamous cell carcinoma, or poorly differentiated basaloid squamous cell carcinoma. The other malignant tumors are very rare...
  11. Malthiery Y, Savagner F. [Energy metabolism of the cancer cell: example of mitochondria-rich endocrine tumors]. Ann Endocrinol (Paris). 2006;67:205-13 pubmed
  12. Gross D, Munter G, Bitan M, Siegal T, Gabizon A, Weitzen R, et al. The role of imatinib mesylate (Glivec) for treatment of patients with malignant endocrine tumors positive for c-kit or PDGF-R. Endocr Relat Cancer. 2006;13:535-40 pubmed
    ..5 months), and disease progression in 1 patient; NET--disease progression in 1 patient. IM does not appear to be useful for treatment of malignant endocrine tumors, also causing significant toxicity in this patient population...
  13. Shirodkar M, Jabbour S. Endocrine incidentalomas. Int J Clin Pract. 2008;62:1423-31 pubmed publisher
    ..The aim of this review article is to familiarise health professionals with all three endocrine incidentalomas, and give some guidance on how to initiate the right endocrine workup...
  14. Imai Y, Taketani T, Maemura K, Takeda N, Harada T, Nojiri T, et al. Genetic analysis in a patient with recurrent cardiac myxoma and endocrinopathy. Circ J. 2005;69:994-5 pubmed
    ..Although it is the most common, usually benign, cardiac tumor, myxoma can cause a critical clinical situation and thus detecting the PRKAR1A mutation can assist with prognosis...
  15. Landry C, Waguespack S, Perrier N. Surgical management of nonmultiple endocrine neoplasia endocrinopathies: state-of-the-art review. Surg Clin North Am. 2009;89:1069-89 pubmed publisher
  16. Cunningham J, Tsolakis A, Jacobson A, Janson E. Connective tissue growth factor expression in endocrine tumors is associated with high stromal expression of alpha-smooth muscle actin. Eur J Endocrinol. 2010;163:691-7 pubmed publisher
    ..This study aimed to examine CTGF expression in relation to local myofibroblast differentiation in a large series of ileal carcinoids and in different types of endocrine tumors...
  17. Lodish M, Stratakis C. Rare and unusual endocrine cancer syndromes with mutated genes. Semin Oncol. 2010;37:680-90 pubmed publisher
    ..Recognition of the familial syndrome associated with a particular patient's endocrine tumor has important implications in terms of prognosis, screening of family members, and screening for associated conditions. ..
  18. Petrasek D, Samtaney R, Cohen D. Glandular regulation of interstitial diffusion: a model and simulation of a novel physiological mechanism. Am J Physiol Endocrinol Metab. 2002;283:E195-206 pubmed
    ..Our results suggest that, in addition to the cellular mechanisms, endocrine glandular networks may have regulatory prowess at the level of interstitial transport...
  19. Kirschner L, Carney J, Pack S, Taymans S, Giatzakis C, Cho Y, et al. Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex. Nat Genet. 2000;26:89-92 pubmed
    ..We conclude that germline mutations in PRKAR1A, an apparent tumour-suppressor gene, are responsible for the CNC phenotype in a subset of patients with this disease...
  20. Murase T, Higurashi T, Akatsuka S, Nagase H, Kawana K, Otani S, et al. [A case of endocrine cell carcinoma of the esophagus successfully treated by chemoradiotherapy]. Gan To Kagaku Ryoho. 2012;39:111-3 pubmed
    ..However, CT showed a liver metastasis relapse in June 2009, and we started AMR as second-line chemotherapy. His general condition went into a decline, however, He died on October 2, 2009...
  21. Larsson G, von Essen L, Sjödén P. Are importance-satisfaction discrepancies with regard to ratings of specific health-related quality-of-life aspects valid indicators of disease- and treatment-related distress among patients with endocrine gastrointestinal tumours?. Eur J Cancer Care (Engl). 2007;16:493-9 pubmed
  22. Zhou C, Tong Y, Wawrowsky K, Bannykh S, Donangelo I, Melmed S. Oct-1 induces pituitary tumor transforming gene expression in endocrine tumors. Endocr Relat Cancer. 2008;15:817-31 pubmed publisher
    ..05) respectively. The results show that Oct-1 transactivates hPTTG1, and both proteins are concordantly overexpressed in endocrine tumors, thus offering a mechanism for endocrine tumor hPTTG1 abundance...
  23. Bifulco M, Malfitano A, Pisanti S, Laezza C. Endocannabinoids in endocrine and related tumours. Endocr Relat Cancer. 2008;15:391-408 pubmed publisher
  24. Kajiwara M, Gotohda N, Konishi M, Nakagohri T, Takahashi S, Kojima M, et al. Cystic endocrine tumor of the pancreas with an atypical multilocular appearance. J Hepatobiliary Pancreat Surg. 2007;14:586-9 pubmed
    ..We finally made a diagnosis of pancreatic endocrine tumor (PET). As PET sometimes shows an atypical multicystic appearance, immunohistochemical staining is mandatory for its correct diagnosis...
  25. Butz H, Kinga N, Racz K, Patocs A. Circulating miRNAs as biomarkers for endocrine disorders. J Endocrinol Invest. 2016;39:1-10 pubmed publisher
    ..Discussions about the technical challenges occurring during identification and measurement of extracellular miRNAs and future perspectives about their roles are also highlighted. ..
  26. Künzel F, Mayer J. Endocrine tumours in the guinea pig. Vet J. 2015;206:268-74 pubmed publisher
    ..Insulinomas have only rarely been documented in guinea pigs and one animal was effectively treated with diazoxide. ..
  27. Scatarige J, Urban B, Horton K, Corl F, Fishman E. Visual survey of cancer dissemination: classic patterns on helical CT. Abdomen and pelvis. J Comput Assist Tomogr. 2001;25:827-35 pubmed
    ..We will emphasize the classic CT appearance of several selected sites and indicate, where appropriate, the primary lesions usually associated with each...
  28. Rodallec M, Vilgrain V, Zins M, Couvelard A, Ruszniewski P, Menu Y. Helical CT of pancreatic endocrine tumors. J Comput Assist Tomogr. 2002;26:728-33 pubmed
    ..In this article, the authors illustrate typical and atypical CT findings of pancreatic endocrine tumors with radiopathologic correlations and give examples of other pancreatic conditions mimicking pancreatic endocrine tumors...
  29. Caplin M, Wiedenmann B. The management of patients with neuroendocrine tumours. Endocr Relat Cancer. 2003;10:425-6 pubmed
  30. Hatch C. Pigmented lesions of the oral cavity. Dent Clin North Am. 2005;49:185-201, ix-x pubmed
    ..This article delineates the factors that will help the clinician differentially diagnose pigmented lesions of the oral cavity. The parameters of care regarding the spectrum of pigmentations are also reviewed...
  31. Imaoka H, Yamao K, Salem A, Sawaki A, Takahashi K, Mizuno N, et al. Pancreatic endocrine neoplasm can mimic serous cystadenoma. Int J Gastrointest Cancer. 2005;35:217-20 pubmed
    ..This case suggests that it is very difficult to distinguish PENs from SCAs based solely on imaging methods. EUS-FNAB is essential for determining the appropriate therapeutic strategy, as it provides the histopathological diagnosis...
  32. Nishimura M, Fujiyama Y. A successful treatment for metastatic liver tumors from endocrine carcinoma of the stomach. Oncol Rep. 2007;17:1077-81 pubmed
    ..Previously published therapies used to treat ECs of the stomach, including the ones used in the current case, are also discussed herein...
  33. Lurye J, Behrend E. Endocrine tumors. Vet Clin North Am Small Anim Pract. 2001;31:1083-110, ix-x pubmed
    ..The syndrome of multiple endocrine neoplasia is also described...
  34. Khan S, Lloyd C, Szyszko T, Win Z, Rubello D, Al Nahhas A. PET imaging in endocrine tumours. Minerva Endocrinol. 2008;33:41-52 pubmed
    ..In addition to imaging GEP-NETs and phaeochromocytoma, it has the potential to be used in a wider range of endocrine tumours...
  35. Baboi L, Milot L, Lartizien C, Roche C, Scoazec J, Pilleul F, et al. Characterization of neuro-endocrine tumors in an athymic nude mouse model using dedicated synchronization strategies for T2-weigted MR imaging at 7T. Conf Proc IEEE Eng Med Biol Soc. 2007;2007:2879-82 pubmed
    ..MR imaging could be used with relevance in the evaluation of new therapeutics protocol for treatment of liver lesions in neuroendocrine tumors using small animal model...
  36. Steinmuller T, Kianmanesh R, Falconi M, Scarpa A, Taal B, Kwekkeboom D, et al. Consensus guidelines for the management of patients with liver metastases from digestive (neuro)endocrine tumors: foregut, midgut, hindgut, and unknown primary. Neuroendocrinology. 2008;87:47-62 pubmed
  37. Kwekkeboom D, Teunissen J, Kam B, Valkema R, de Herder W, Krenning E. Treatment of patients who have endocrine gastroenteropancreatic tumors with radiolabeled somatostatin analogues. Hematol Oncol Clin North Am. 2007;21:561-73; x pubmed
    ..Also, if kidney-protective agents are used, the side effects of this therapy are few and mild. These data compare favorably with the limited number of alternative treatment approaches...
  38. Salehi F, Kovacs K, Scheithauer B, Lloyd R, Cusimano M. Pituitary tumor-transforming gene in endocrine and other neoplasms: a review and update. Endocr Relat Cancer. 2008;15:721-43 pubmed publisher
    ..In addition, we discuss in vitro and in vivo therapeutic models targeting PTTG overexpression...
  39. Missana A, Meyer P. [Endocrinology]. Rev Med Suisse. 2012;8:18-22 pubmed
    ..Tyrosine-kinase inhibitors have now been tested in the treatment of progressive differentiated iodine refractory thyroid carcinomas or medullary carcinomas and showed modestly encouraging results...
  40. Spiegel A. Focus on hereditary endocrine neoplasia. Cancer Cell. 2004;6:327-32 pubmed
  41. Ochoa Carrillo F, Chávez Mac Gregor M, Green Renner D, Green Schneeweiss L. [Paraneoplastic syndromes. Associated with lung cancer]. Cir Cir. 2003;71:150-61 pubmed
    ..In this update, we review paraneoplastic syndromes associated with lung cancer, potential mechanisms, clinical manifestations, diagnosis, and treatment...
  42. Stepien H, Kołomecki K, Pasieka Z, Komorowski J, Stepien T, Kuzdak K. Angiogenesis of endocrine gland tumours--new molecular targets in diagnostics and therapy. Eur J Endocrinol. 2002;146:143-51 pubmed
    ..The studies on the significance of neoangiogenesis in the progression of endocrine gland neoplasms have recently become one of the most rapidly evolving branches of molecular endocrinology...
  43. Pacak K, Koch C, Eisenhofer G. Current approaches and new advances in endocrine hypertension. Trends Endocrinol Metab. 2002;13:96-7 pubmed
  44. Schott M, Seissler J. Dendritic cell vaccination: new hope for the treatment of metastasized endocrine malignancies. Trends Endocrinol Metab. 2003;14:156-62 pubmed
  45. Calender A. [Pathogenic patterns of genetic predisposition to endocrine tumors]. Nephrol Ther. 2006;2 Suppl 2:S127-36 pubmed
    ..These hereditary models of endocrine cancer contribute as much to further physiopathogenic knowledge as to the therapeutic recommendations for managing these syndromes...
  46. Coyne J, O Connor B. Mixed adenoma-endocrine tumour of the stomach. Histopathology. 2010;57:492-4 pubmed publisher
  47. Brennan M. Invited commentary: Surgery and chemotherapy for peritoneal carcinomatosis--more about selection and biology than treatment?. Surgery. 2005;137:417-8 pubmed
  48. Kouvaraki M, Shapiro S, Perrier N, Cote G, Gagel R, Hoff A, et al. RET proto-oncogene: a review and update of genotype-phenotype correlations in hereditary medullary thyroid cancer and associated endocrine tumors. Thyroid. 2005;15:531-44 pubmed
    ..Recommendations on the timing of prophylactic thyroidectomy and the extent of surgery are based upon a model that utilizes genotype- phenotype correlations to stratify mutations into three risk levels...
  49. Garai I, Toth C, Szabados L, Sovago J, Tóth L, Csiki Z. [Metabolic imaging--PET, PET/CT--in oncologic surgery]. Magy Seb. 2008;61:217-24 pubmed publisher
    ..In the present paper the most frequent indications of PET/CT examinations are reviewed, with special attention to cases relevant to the everyday surgical practice. The applicability of this technique is also considered...
  50. Safo A, Li R, Vickers S, Schmechel S, Pambuccian S. Endoscopic ultrasound-guided fine-needle aspiration diagnosis of clear-cell pancreatic endocrine neoplasm in a patient with von Hippel-Lindau disease: a case report. Diagn Cytopathol. 2009;37:365-72 pubmed publisher
  51. Eberle A, Beglinger C. Does 177Lu-labeled octreotate improve the rate of remission of endocrine gastroenteropancreatic tumors?. Nat Clin Pract Endocrinol Metab. 2005;1:20-1 pubmed
  52. Ruszniewski P, Terris B. [Natural history and prognosis of pancreatic endocrine tumors]. Gastroenterol Clin Biol. 2003;27:S20-5 pubmed
  53. Montravers F, Grahek D, Kerrou K, Ruszniewski P, de Beco V, Aide N, et al. Can fluorodihydroxyphenylalanine PET replace somatostatin receptor scintigraphy in patients with digestive endocrine tumors?. J Nucl Med. 2006;47:1455-62 pubmed