duodenal neoplasms

Summary

Summary: Tumors or cancer of the DUODENUM.

Top Publications

  1. Westgaard A, Pomianowska E, Clausen O, Gladhaug I. Intestinal-type and pancreatobiliary-type adenocarcinomas: how does ampullary carcinoma differ from other periampullary malignancies?. Ann Surg Oncol. 2013;20:430-9 pubmed publisher
    ..We evaluated whether the histologic type itself is more important for long-term survival than the fact that the tumor originated in the ampulla...
  2. Relles D, Baek J, Witkiewicz A, Yeo C. Periampullary and duodenal neoplasms in neurofibromatosis type 1: two cases and an updated 20-year review of the literature yielding 76 cases. J Gastrointest Surg. 2010;14:1052-61 pubmed publisher
    ..Here, we briefly describe two male patients with NF1 and review the recent literature on this topic...
  3. Okubo Y, Yokose T, Tuchiya M, Mituda A, Wakayama M, Hasegawa C, et al. Duodenal gangliocytic paraganglioma showing lymph node metastasis: a rare case report. Diagn Pathol. 2010;5:27 pubmed publisher
    ..In addition to the rarity of the tumor, we are describing here the present case suggests the malignant potency of the tumor despite lack of acceptable prognostic indicators for neuroendocrine tumor...
  4. Senadhi V, Dutta S. Testicular seminoma metastasis to the gastrointestinal tract and the necessity of surgery. J Gastrointest Cancer. 2012;43:499-501 pubmed publisher
    ..We present a case of chemoresistant pure testicular seminoma with metastasis to the duodenum with a complication of a massive upper GI bleed requiring emergent surgery...
  5. Chen H, Xu G, Wang L, Chen Y, Li Y. Sonographic features of duodenal lipomas in eight clinicopathologically diagnosed patients. World J Gastroenterol. 2011;17:2855-9 pubmed publisher
    ..To investigate the sonographic features and diagnostic value of endoscopic ultrasonography (EUS) for duodenal lipomas (DLs)...
  6. van Heumen B, Nieuwenhuis M, van Goor H, Mathus Vliegen L, Dekker E, Gouma D, et al. Surgical management for advanced duodenal adenomatosis and duodenal cancer in Dutch patients with familial adenomatous polyposis: a nationwide retrospective cohort study. Surgery. 2012;151:681-90 pubmed publisher
    ..The clinical challenge is to perform duodenectomy before cancer develops; however, procedures are associated with complications. Our aim was to gain insight into the pros and cons of prophylactic duodenectomy...
  7. Poves I, Burdio F, Alonso S, Seoane A, Grande L. Laparoscopic pancreas-sparing subtotal duodenectomy. JOP. 2011;12:62-5 pubmed
    ..Segmental duodenal resection is an appropriate operation for selected cases of primary adenocarcinoma of the duodenum of the 3rd and 4th portions of the duodenum...
  8. Kanthan R, Gomez D, Senger J, Kanthan S. Endoscopic biopsies of duodenal polyp/mass lesions: a surgical pathology review. J Clin Pathol. 2010;63:921-5 pubmed publisher
    ..Endoscopic biopsies of duodenal polyp/mass lesions are uncommon surgical pathology specimens. A surgical review with a report on three unusual duodenal polyp/mass lesions is presented...
  9. Sohn J, Jeon S, Cho C, Jung M, Kim S, Lee D, et al. Endoscopic resection of duodenal neoplasms: a single-center study. Surg Endosc. 2010;24:3195-200 pubmed publisher
    ..Endoscopic resection of superficial premalignant or malignant lesions of the gastrointestinal tract is used with increasing frequency. This study aimed to evaluate the safety and efficacy of endoscopic resection of duodenal neoplasms.

More Information

Publications62

  1. Pomianowska E, Grzyb K, Westgaard A, Clausen O, Gladhaug I. Reclassification of tumour origin in resected periampullary adenocarcinomas reveals underestimation of distal bile duct cancer. Eur J Surg Oncol. 2012;38:1043-50 pubmed publisher
    ..The proximity of the structures of possible origin renders it difficult to obtain a correct diagnosis, which might lead to inconsistencies in reported data and inappropriate adjuvant treatment...
  2. Bulow S, Christensen I, Højen H, Bjork J, Elmberg M, Jarvinen H, et al. Duodenal surveillance improves the prognosis after duodenal cancer in familial adenomatous polyposis. Colorectal Dis. 2012;14:947-52 pubmed publisher
    ..Endoscopic surveillance has been recommended, but the effect has not yet been documented. The aim of this study was to present the results of long-term duodenal surveillance and to evaluate the risk of cancer development...
  3. Gauger P, Doherty G, Broome J, Miller B, Thompson N. Completion pancreatectomy and duodenectomy for recurrent MEN-1 pancreaticoduodenal endocrine neoplasms. Surgery. 2009;146:801-6; discussion 807-8 pubmed publisher
  4. Ohtsuki Y, Watanabe R, Kimura M, Okamoto T, Murakami S, Mizukami Y, et al. Immunohistochemical and electron microscopic studies of a case of duodenal gangliocytic paraganglioma. Med Mol Morphol. 2009;42:245-9 pubmed publisher
    ..The immunohistochemical and ultrastructural findings of a case of GPG are reported, focusing on three major cellular components: GCs, ECs, and SCs...
  5. Kanthan R, Senger J, Diudea D, Kanthan S. A review of duodenal metastases from squamous cell carcinoma of the cervix presenting as an upper gastrointestinal bleed. World J Surg Oncol. 2011;9:113 pubmed publisher
    ..Awareness of such infrequent patterns of metastases in cervical cancer confirmed by histopathological diagnosis is important for best practice therapeutic decisions in these patients...
  6. Hughes J, Cook J, Said A, Chong S, Towu E, Reidy J. Gastrointestinal stromal tumour of the duodenum in a 7-year-old boy. Pediatr Radiol. 2004;34:1024-7 pubmed
    ..We emphasize the importance of a thorough abdominal US examination in children with GI haemorrhage and the consideration of GIST in the diagnosis after the common causes have been excluded...
  7. Hatzaras I, Palesty J, Abir F, Sullivan P, Kozol R, Dudrick S, et al. Small-bowel tumors: epidemiologic and clinical characteristics of 1260 cases from the connecticut tumor registry. Arch Surg. 2007;142:229-35 pubmed
    ..To examine the epidemiology and clinical characteristics of small-bowel cancer...
  8. Witkiewicz A, Galler A, Yeo C, Gross S. Gangliocytic paraganglioma: case report and review of the literature. J Gastrointest Surg. 2007;11:1351-4 pubmed
    ..We conclude that surgical therapy of these neoplasms should not be limited to local resection, as disease recurrence, lymph node involvement, and rarely distant metastasis may occur...
  9. Lepisto A, Kiviluoto T, Halttunen J, Järvinen H. Surveillance and treatment of duodenal adenomatosis in familial adenomatous polyposis. Endoscopy. 2009;41:504-9 pubmed publisher
    ..We analyzed the results of endoscopic surveillance and different treatment modalities of duodenal adenomatosis in patients with FAP...
  10. Kruger S, Noack F, Blöchle C, Feller A. Primary malignant melanoma of the small bowel: a case report and review of the literature. Tumori. 2005;91:73-6 pubmed
    ..A literature review reveals that this rare neoplasm is associated with a slight predilection for the male gender, a predilection for the ileum and a poor prognosis...
  11. Misra S, Dwivedi M, Misra V, Dharmani S, Gupta M. Duodenal metastases from squamous cell carcinoma of the lung: endoscopic management of bleeding and biliary and duodenal obstruction. Indian J Gastroenterol. 2004;23:185-6 pubmed
    ..Intestinal metastases from cancer of the lung are rare. We report a 65-year-old man with duodenal metastases from squamous cell cancer causing GI bleeding and biliary and duodenal obstruction; these were managed endoscopically...
  12. Pitt H. Duodenal cancer: endoscopic or surgical resection?. J Clin Gastroenterol. 2003;37:356-7 pubmed
  13. Hellies R, Sulis R, Puliga A, Pala M, Pietrangeli M. [GIST: surgical treatment of 34 cases]. Tumori. 2003;89:133-4 pubmed
    ..There was no operative mortality or morbidity. Actual survival is 67.6%. Prognostic prediction on the basis of histological findings is difficult, thus after surgery we suggest a long last follow-up...
  14. Perez A, Saltzman J, Carr Locke D, Brooks D, Osteen R, Zinner M, et al. Benign nonampullary duodenal neoplasms. J Gastrointest Surg. 2003;7:536-541 pubmed publisher
    Benign duodenal neoplasms (BDNs) are uncommon, and their optimal management remains undefined. We analyzed all cases of BDN treated at our institution during a 10-year period (January 1990 through January 2000)...
  15. Gallagher M, Phillips R, Bulow S. Surveillance and management of upper gastrointestinal disease in Familial Adenomatous Polyposis. Fam Cancer. 2006;5:263-73 pubmed
  16. Latchford A, Neale K, Spigelman A, Phillips R, Clark S. Features of duodenal cancer in patients with familial adenomatous polyposis. Clin Gastroenterol Hepatol. 2009;7:659-63 pubmed publisher
    ..We reviewed cases of duodenal cancer in patients with FAP to identify factors that determine long-term cancer risk...
  17. Huang D, Wang X, Zhou W, Xin Y, Mou Y, Cai X. Polypropylene mesh-reinforced pancreaticojejunostomy for periampullar neoplasm. World J Gastroenterol. 2007;13:6072-5 pubmed
    ..To evaluate the effect of polypropylene mesh-reinforced pancreatojejunostomy on pancreatic leakage...
  18. Chiarugi M, Galatioto C, Lippolis P, Zocco G, Seccia M. Gastrointestinal stromal tumour of the duodenum in childhood: a rare case report. BMC Cancer. 2007;7:79 pubmed
    ..In young patients duodenal GISTs may be a source of potentially lethal haemorrhage and this adds diagnostic and therapeutic dilemmas to the concern about the long-term outcome...
  19. Morita T, Tamura S, Yokoyama Y, Onishi T, Kuratani Y, Mizuta H, et al. Endoscopic resection of a duodenal gangliocytic paraganglioma. Dig Dis Sci. 2007;52:1400-4 pubmed
    ..An endoscopic ultrasonography showed a round, well-demarcated, inhomogeneous, submucosal tumor in the 3rd-4th layer. We resected it by endoscopic mucosal resection...
  20. Stawowy M, Kruse A, Mortensen F, Funch Jensen P. Endoscopic stenting for malignant gastric outlet obstruction. Surg Laparosc Endosc Percutan Tech. 2007;17:5-9 pubmed
    ..The obstruction was localized in the stomach (n=5), gastrojejunostomy (n=3), or the duodenum (n=16). Self-expanding metal stents were delivered endoscopically under fluoroscopic control...
  21. Wheeler J, Warren B, Mortensen N, Kim H, Biddolph S, Elia G, et al. An insight into the genetic pathway of adenocarcinoma of the small intestine. Gut. 2002;50:218-23 pubmed
    ..Although the adenoma to carcinoma pathway in colorectal cancer is well described, the mechanisms of carcinogenesis in the small intestine remain unclear...
  22. Dalenback J, Havel G. Local endoscopic removal of duodenal carcinoid tumors. Endoscopy. 2004;36:651-5 pubmed
  23. Dabaja B, Suki D, Pro B, Bonnen M, Ajani J. Adenocarcinoma of the small bowel: presentation, prognostic factors, and outcome of 217 patients. Cancer. 2004;101:518-26 pubmed
    ..Primary adenocarcinoma of the small bowel is a rare neoplasm, and to the authors' knowledge, few studies to date have addressed the topic...
  24. Stell D, Mayer D, Mirza D, Buckels J. Delayed diagnosis and lower resection rate of adenocarcinoma of the distal duodenum. Dig Surg. 2004;21:434-8; discussion 438-9 pubmed
    ..Prolonged survival following resection of the primary tumour is possible, whilst irresectable disease has a very poor prognosis. The factors determining resectability of the primary tumour have not been addressed...
  25. Akkus M, Kismet K, Erel S, Adibelli M, Pulat H. Case report: duodenal stromal tumor. Acta Gastroenterol Belg. 2005;68:95-7 pubmed
    ..Although stromal tumors are relatively rare in the duodenum, in the case of upper gastrointestinal obstruction and anemia, this type of tumors should be considered in differential diagnosis...
  26. Hompes D, Topal B, Ectors N, Aerts R, Penninckx F. Gastro-intestinal stromal tumour of the duodenum: extreme presentation in two cases. Acta Chir Belg. 2004;104:110-3 pubmed
    ..This work will illustrate that duodenal GIST can occur in extreme presentations, diverging from vague complaints to directly life threatening symptoms...
  27. Akino K, Kondo Y, Ueno A, Yamazaki K, Hosokawa M, Shimoji H, et al. Carcinoma of duodenum arising from Brunner's gland. J Gastroenterol. 2002;37:293-6 pubmed
    ..We report here a case of early duodenal carcinoma arising from Brunner's gland, whose origin was proven by mucin immunohistochemistry...
  28. Akerstrom G, Hessman O, Skogseid B. Timing and extent of surgery in symptomatic and asymptomatic neuroendocrine tumors of the pancreas in MEN 1. Langenbecks Arch Surg. 2002;386:558-69 pubmed
    ..More extensive surgical tumor reduction is believed to reduce the risks for malignant progression of the pancreaticoduodenal tumors, but this requires further evaluation in MEN 1...
  29. Yoon C, Song H, Shin J, Bae J, Jung G, Kichikawa K, et al. Malignant duodenal obstructions: palliative treatment using self-expandable nitinol stents. J Vasc Interv Radiol. 2006;17:319-26 pubmed
    ..To assess the efficacy of fluoroscopic per oral placement of self-expandable nitinol stents in the palliative treatment of malignant duodenal obstructions...
  30. Stratopoulos C, Soonawalla Z, Piris J, Friend P. Hepatopancreatoduodenectomy for metastatic duodenal gastrointestinal stromal tumor. Hepatobiliary Pancreat Dis Int. 2006;5:147-50 pubmed
    ..We present a case of a metastatic duodenal gastrointestinal stromal tumor that was successfully treated by simultaneous right hemihepatectomy and pancreaticoduodenectomy...
  31. Bal A, Joshi K, Vaiphei K, Wig J. Primary duodenal neoplasms: a retrospective clinico-pathological analysis. World J Gastroenterol. 2007;13:1108-11 pubmed
    To analyze the clinico-pathological spectrum of primary duodenal neoplasms.
  32. Hung F, Kuo C, Chuah S, Kuo C, Chen Y, Lu S, et al. Clinical analysis of primary duodenal adenocarcinoma: an 11-year experience. J Gastroenterol Hepatol. 2007;22:724-8 pubmed
    ..The aim of the present study was to review the clinical features of PDA patients in an attempt to determine the prognostic factors and the influence of OJ on survival...
  33. Bucher P, Gervaz P, Morel P. Long-term results of radical resection for locally advanced duodenal adenocarcinoma. Hepatogastroenterology. 2005;52:1727-9 pubmed
    ..Duodenal adenocarcinomas are uncommon tumors characterized by non-specific symptoms and late diagnosis. The objective of this study was to assess long-term results of locally advanced duodenal adenocarcinoma treated by surgical resection...
  34. Tocchi A, Mazzoni G, Puma F, Miccini M, Cassini D, Bettelli E, et al. Adenocarcinoma of the third and fourth portions of the duodenum: results of surgical treatment. Arch Surg. 2003;138:80-5 pubmed
    ..To verify the adequacy of duodenal segmentectomy after intestinal derotation in the treatment of primary adenocarcinoma of the third and fourth portions of the duodenum...
  35. Scelo G, Boffetta P, Hemminki K, Pukkala E, Olsen J, Andersen A, et al. Associations between small intestine cancer and other primary cancers: an international population-based study. Int J Cancer. 2006;118:189-96 pubmed
    ..g., defects in mismatch or other DNA repair pathways) and environmental (e.g., dietary) factors...
  36. Vasen H, Moslein G, Alonso A, Aretz S, Bernstein I, Bertario L, et al. Guidelines for the clinical management of familial adenomatous polyposis (FAP). Gut. 2008;57:704-13 pubmed publisher
    ..The guidelines described herein may be helpful in the appropriate management of FAP families. In order to improve the care of these families further, prospective controlled studies should be undertaken...
  37. Bulow S, Bjork J, Christensen I, Fausa O, Jarvinen H, Moesgaard F, et al. Duodenal adenomatosis in familial adenomatous polyposis. Gut. 2004;53:381-6 pubmed
    ..The prevalence of duodenal carcinoma is much higher in familial adenomatous polyposis (FAP) than in the background population, and duodenal adenomatosis is found in most polyposis patients...
  38. Triponez F, Goudet P, Dosseh D, Cougard P, Bauters C, Murat A, et al. Is surgery beneficial for MEN1 patients with small (< or = 2 cm), nonfunctioning pancreaticoduodenal endocrine tumor? An analysis of 65 patients from the GTE. World J Surg. 2006;30:654-62; discussion 663-4 pubmed
    ..We therefore investigated the effect of surgery on survival and tumor progression in MEN1 patients with NFPET < or = 2 cm by analyzing data from the Groupe des Tumeurs Endocrines (GTE) registry...
  39. Chang W, Chai C, Lee K. Unusual upper gastrointestinal bleeding due to late metastasis from renal cell carcinoma: a case report. Kaohsiung J Med Sci. 2004;20:137-41 pubmed
    ..The possibility of late recurrent renal cell carcinoma metastasis to the gastrointestinal tract should be kept in mind, although it is rare. If the patient is fit for surgery, metastatectomy is the first choice of treatment...
  40. Hu J, Miao X, Zhong D, Dai W, Liu W, Hu W. Surgical treatment of primary duodenal adenocarcinoma. Hepatogastroenterology. 2006;53:858-62 pubmed
    ..Our purpose was to review the outcome of the patients with primary duodenal adenocarcinoma and determine factors influencing survival...
  41. Adler D, Baron T. Endoscopic palliation of malignant gastric outlet obstruction using self-expanding metal stents: experience in 36 patients. Am J Gastroenterol. 2002;97:72-8 pubmed
    ..Malignant gastric outlet obstruction is seen in the setting of a variety of cancers, most commonly pancreatic. Self-expanding metal stents can be used to palliate these patients and restore the ability to eat...
  42. Tsang A, Nash J, Fordham M, Hartley M, Poston G. The management of retroperitoneal liposarcoma with synchronous intra-duodenal sarcoma. Eur J Surg Oncol. 2003;29:515-8 pubmed
    ..Intra-duodenal involvement with sarcoma was found intra-operatively. We discuss the management of this condition in the context of an illustrative case in our recent experience...
  43. Roy S, Raskin L, Raymond V, Thibodeau S, Mody R, Gruber S. Pediatric duodenal cancer and biallelic mismatch repair gene mutations. Pediatr Blood Cancer. 2009;53:116-20 pubmed publisher
    ..We report the case of a 16-year-old female with duodenal adenocarcinoma and past history of medulloblastoma found to have a novel germline bialleleic truncating mutation (c.[949C>T]+[949C>T]) of the PMS2 gene...
  44. Plaza J, Vitellas K, Marsh W. Duodenal gangliocytic paraganglioma: a radiological-pathological correlation. Ann Diagn Pathol. 2005;9:143-7 pubmed
    ..We report a case of duodenal gangliocytic paraganglioma and discuss the radiological and pathological differential diagnosis of this rare entity...
  45. Perez R, Coser R, Kiss D, Iwashita R, Jukemura J, Cunha J, et al. Combined resection of the duodenum and pancreas for locally advanced colon cancer. Curr Surg. 2005;62:613-7 pubmed
    ..This procedure is the preferred treatment strategy because it seems to be associated with improved overall survival rates...
  46. Xiao R, Carter J, Linz A, Ferguson M, Badger T, Simmen F. Dietary whey protein lowers serum C-peptide concentration and duodenal SREBP-1c mRNA abundance, and reduces occurrence of duodenal tumors and colon aberrant crypt foci in azoxymethane-treated male rats. J Nutr Biochem. 2006;17:626-34 pubmed
    ..Results indicate potential physiological linkages of dietary protein type with circulating C-peptide (and by inference insulin), local expression of SREBP-1c gene and propensity for small intestine tumorigenesis...
  47. Berkhout M, Gosens M, Brouwer K, Peters W, Nagengast F, van Krieken J, et al. Loss of extracellular E-cadherin in the normal mucosa of duodenum and colon of patients with familial adenomatous polyposis. Hum Pathol. 2006;37:1389-99 pubmed
    ..The loss of extracellular E-cadherin in the normal duodenal and colonic mucosa of patients with FAP might play a role in the high susceptibility of these tissues for (pre-) malignant transformation...
  48. Dormann A, Meisner S, Verin N, Wenk Lang A. Self-expanding metal stents for gastroduodenal malignancies: systematic review of their clinical effectiveness. Endoscopy. 2004;36:543-50 pubmed
    ..Recently, metal stents have emerged as a new therapeutic option. The aim of the present study was to review the currently published evidence on the effectiveness and safety of this form of endoscopic treatment...
  49. Mann C, Bramhall S, Buckels J, Taniere P. An unusual case of duodenal obstruction-gangliocytic paraganglioma. J Hepatobiliary Pancreat Surg. 2009;16:562-5 pubmed publisher
    ..We discuss the management of this unusual case and review the literature...
  50. Brosens L, Keller J, Offerhaus G, Goggins M, Giardiello F. Prevention and management of duodenal polyps in familial adenomatous polyposis. Gut. 2005;54:1034-43 pubmed
  51. Kwon S, Cha H, Jung S, Kim B, Park J, Jeong I, et al. A gastrointestinal stromal tumor of the duodenum masquerading as a pancreatic head tumor. World J Gastroenterol. 2007;13:3396-9 pubmed
    ..Here, we report a case of duodenal GIST, which was assessed as a pancreatic head tumor preoperatively...
  52. Urso E, Pucciarelli S, Cassaro M, Agostini M, Nitti D. Long-term follow-up after endoscopic forceps biopsies for early stage duodenal carcinoid: case report and review of endoscopic treatments. Endoscopy. 2007;39 Suppl 1:E128 pubmed
  53. Cwikiel W, Andren Sandberg A. Diagnostic difficulties with duodenal malignancies revisited: a new strategy. Gastrointest Radiol. 1991;16:301-4 pubmed
    ..Five cases of duodenal tumors are presented. The value of various diagnostic imaging methods in the assessment of tumors is also discussed. Modified duodenography is proposed as a method that should improve the diagnostic accuracy...