alveolar soft part sarcoma

Summary

Summary: A variety of rare sarcoma having a reticulated fibrous stroma enclosing groups of sarcoma cells, which resemble epithelial cells and are enclosed in alveoli walled with connective tissue. It is a rare tumor, usually occurring between 15 and 35 years of age. It appears in the muscles of the extremities in adults and most commonly in the head and neck regions of children. Though slow-growing, it commonly metastasizes to the lungs, brain, bones, and lymph nodes. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1365)

Top Publications

  1. Kanhere H, Pai P, Neeli S, Kantharia R, Saoji R, D Cruz A. Alveolar soft part sarcoma of the head and neck. Int J Oral Maxillofac Surg. 2005;34:268-72 pubmed
    b>Alveolar soft part sarcoma (ASPS) of the head and neck region has been a rarely reported entity. These lesions have a high propensity for distant metastasis...
  2. Folpe A, Deyrup A. Alveolar soft-part sarcoma: a review and update. J Clin Pathol. 2006;59:1127-32 pubmed
    ..The historical, histopathological, ultrastructural, immunohistochemical and genetic aspects of ASPS are reviewed in this article...
  3. Stacchiotti S, Tamborini E, Marrari A, Brich S, Rota S, Orsenigo M, et al. Response to sunitinib malate in advanced alveolar soft part sarcoma. Clin Cancer Res. 2009;15:1096-104 pubmed publisher
    b>Alveolar soft part sarcoma (ASPS) is a rare, chemoresistant soft tissue sarcoma. ASPS harbors the t(17-X) (p11...
  4. Trabelsi A, Ben Abdelkrim S, Taher Yacoubi M, Mlika S, Hmissa S, Mokni M, et al. [Primary alveolar soft part sarcoma of the lung]. Rev Mal Respir. 2009;26:329-32 pubmed
    b>Alveolar soft part sarcoma is rare; it mainly appears in the lower extremities in adults and the head and neck in children. Primary pulmonary occurrence of this tumour is exceptional.
  5. Machhi J, Kouzova M, Komorowski D, Asma Z, Chivukala M, Basir Z, et al. Crystals of alveolar soft part sarcoma in a fine needle aspiration biopsy cytology smear. A case report. Acta Cytol. 2002;46:904-8 pubmed
    b>Alveolar soft part sarcoma (ASPS) is a rare soft tissue tumor. It has characteristic histomorphology, with typical ultrastructural features demonstrating unique crystalloids...
  6. Zilber S, Brouland J, Voisin M, Ziza J, Desplaces N, Chekulaev D, et al. Colic metastases of alveolar soft-part sarcoma: a case report and review of the literature. Ann Diagn Pathol. 2003;7:306-9 pubmed
    ..The treatment of these two caecal metastases, revealed by an anemia, consisted in laparoscopic right colectomy...
  7. Azizi A, Haberler C, Czech T, Gupper A, Prayer D, Breitschopf H, et al. Vascular-endothelial-growth-factor (VEGF) expression and possible response to angiogenesis inhibitor bevacizumab in metastatic alveolar soft part sarcoma. Lancet Oncol. 2006;7:521-3 pubmed
  8. Anderson M, Hornicek F, Gebhardt M, Raskin K, Mankin H. Alveolar soft part sarcoma: a rare and enigmatic entity. Clin Orthop Relat Res. 2005;438:144-8 pubmed
    b>Alveolar soft part sarcoma is a rare malignant tumor with unusual clinical behavior...
  9. BaniHani M, Al Manasra A. Spontaneous regression in alveolar soft part sarcoma: case report and literature review. World J Surg Oncol. 2009;7:53 pubmed publisher
    ..Sarcomas are a type of malignant tumors that arise from connective tissue. They are most of the time found in extremities..

More Information

Publications83

  1. Gunay C, Atalar H, Kaygusuz G, Yildiz Y, Saglik Y. [Alveolar soft part sarcoma of the extremities: an evaluation of four cases]. Acta Orthop Traumatol Turc. 2007;41:326-31 pubmed
    We presented four patients (3 women, 1 man; mean age 40 years; range 20 to 56 years) who had alveolar soft part sarcoma in the left arm, right elbow, right tibia, and left thigh, respectively. All the patients presented with a mass...
  2. Argani P, Lal P, Hutchinson B, Lui M, Reuter V, Ladanyi M. Aberrant nuclear immunoreactivity for TFE3 in neoplasms with TFE3 gene fusions: a sensitive and specific immunohistochemical assay. Am J Surg Pathol. 2003;27:750-61 pubmed
    ..2. This group of tumors includes alveolar soft part sarcoma and a specific subset of renal carcinomas that tend to affect young patients...
  3. Hoshino M, Ogose A, Kawashima H, Izumi T, Hotta T, Hatano H, et al. Molecular analyses of cell origin and detection of circulating tumor cells in the peripheral blood in alveolar soft part sarcoma. Cancer Genet Cytogenet. 2009;190:75-80 pubmed publisher
    b>Alveolar soft part sarcoma (ASPS) is a distinct, rare soft tissue tumor with an unknown histogenesis and a tendency for late widespread metastases to lung, bone, and brain...
  4. Carter J, Evans T, Tucker J. Cytologic diagnosis of alveolar soft part sarcoma of the lower extremity by fine needle aspiration and correlation with core biopsy: a case report. Acta Cytol. 2008;52:459-63 pubmed
    b>Alveolar soft part sarcoma is a rare soft tissue tumor of uncertain origin that is generally slow growing but unmistakably malignant due to its propensity for metastasis to lung, bone and brain early in the course of disease...
  5. Lazar A, Das P, Tuvin D, Korchin B, Zhu Q, Jin Z, et al. Angiogenesis-promoting gene patterns in alveolar soft part sarcoma. Clin Cancer Res. 2007;13:7314-21 pubmed
    We examined a cohort of patients with alveolar soft part sarcoma (ASPS) treated at our institution and showed the characteristic ASPSCR1-TFE3 fusion transcript in their tumors...
  6. Marchac A, Picard A, Landman Parker J, Larroquet M, Vazquez M, Franchi G. [A pediatric case of Alveolar Soft Part Sarcoma]. Rev Stomatol Chir Maxillofac. 2007;108:547-50 pubmed
    b>Alveolar Soft Part Sarcoma (ASPS) is a rare malignant tumor arising from skeletal muscles and occurring usually in young adults. It is a solid chemo resistant tumor...
  7. Argani P, Antonescu C, Illei P, Lui M, Timmons C, Newbury R, et al. Primary renal neoplasms with the ASPL-TFE3 gene fusion of alveolar soft part sarcoma: a distinctive tumor entity previously included among renal cell carcinomas of children and adolescents. Am J Pathol. 2001;159:179-92 pubmed
    The unbalanced translocation, der(17)t(X;17)(p11.2;q25), is characteristic of alveolar soft part sarcoma (ASPS). We have recently shown that this translocation fuses the TFE3 transcription factor gene at Xp11...
  8. Bisogno G, Rosolen A, Carli M. Interferon alpha for alveolar soft part sarcoma. Pediatr Blood Cancer. 2005;44:687-8 pubmed
  9. Ladanyi M, Lui M, Antonescu C, Krause Boehm A, Meindl A, Argani P, et al. The der(17)t(X;17)(p11;q25) of human alveolar soft part sarcoma fuses the TFE3 transcription factor gene to ASPL, a novel gene at 17q25. Oncogene. 2001;20:48-57 pubmed
    b>Alveolar soft part sarcoma (ASPS) is an unusual tumor with highly characteristic histopathology and ultrastructure, controversial histogenesis, and enigmatic clinical behavior...
  10. Zarrin Khameh N, Kaye K. Alveolar soft part sarcoma. Arch Pathol Lab Med. 2007;131:488-91 pubmed
    This article provides an overview of the pathology of alveolar soft part sarcoma, focused on its morphology, special stains useful in diagnosis, and the clinical and radiographic features of the disease...
  11. Fanburg Smith J, Miettinen M, Folpe A, Weiss S, Childers E. Lingual alveolar soft part sarcoma; 14 cases: novel clinical and morphological observations. Histopathology. 2004;45:526-37 pubmed
    b>Alveolar soft part sarcoma (ASPS) is a rare sarcoma in the buttocks or thigh of young adults, often with metastases to lung, brain, or bone. This study examines the morphological and clinical features of lingual ASPS.
  12. Roma A, Yang B, Senior M, Goldblum J. TFE3 immunoreactivity in alveolar soft part sarcoma of the uterine cervix: case report. Int J Gynecol Pathol. 2005;24:131-5 pubmed
    b>Alveolar soft part sarcoma (ASPS) is an uncommon neoplasm that has only rarely been reported in the female genital tract...
  13. Uppal S, Aviv H, Patterson F, Cohen S, Benevenia J, Aisner S, et al. Alveolar soft part sarcoma--reciprocal translocation between chromosome 17q25 and Xp11. Report of a case with metastases at presentation and review of the literature. Acta Orthop Belg. 2003;69:182-7 pubmed
    The molecular pathogenesis of alveolar soft part sarcoma, a rare tumor with uncertain histogenesis, was elucidated recently and was shown to be due to a translocation between chromosome 17q25 and Xp11 resulting in a fusion product between ..
  14. van Ruth S, van Coevorden F, Peterse J, Kroon B. Alveolar soft part sarcoma. a report of 15 cases. Eur J Cancer. 2002;38:1324-8 pubmed
    ..5 patients are still free of disease after a median period of 234 months (12-295 months). Alveolar soft part sarcoma is found especially in young adults. When diagnosed, it is often metastasised with a poor prognosis...
  15. Tucker J. Crystal-deficient alveolar soft part sarcoma. Ultrastruct Pathol. 1993;17:279-86 pubmed
    Classically, ultrastructural examination of alveolar soft part sarcoma reveals large, dramatic, rhomboid to needlelike crystals with a characteristic substructure...
  16. Wakely P, McDermott J, Ali S. Cytopathology of alveolar soft part sarcoma: a report of 10 cases. Cancer. 2009;117:500-7 pubmed publisher
    b>Alveolar soft part sarcoma (ASPS) rarely is subjected to cytopathologic evaluation. With the exception of some very small series, the literature is limited to case reports...
  17. Montgomery J, Conrad G, Sinha P, Absher K. FDG PET of alveolar soft part sarcoma. Clin Nucl Med. 2010;35:827-9 pubmed publisher
    b>Alveolar soft part sarcoma (ASPS) is a very rare, but distinctive type of soft tissue sarcoma, whose name is derived from the pseudoalveolar appearance of its histology...
  18. Lai Y, Chiou H, Wu H, Chou Y, Wang H, Chen P. Ultrasonographic and MR findings of alveolar soft part sarcoma. J Chin Med Assoc. 2009;72:336-9 pubmed publisher
    b>Alveolar soft part sarcoma (ASPS) is a rare soft-tissue sarcoma, commonly occurring in children and adolescents. The tumor mostly involves the lower extremities. The prognosis of the patient depends on whether there is metastasis...
  19. Zamani F, Jabbari M, Alimohamadi S, Shakeri R, Rostami Z, Abedi B, et al. Primary alveolar soft part sarcoma of chest wall: a case report and review of the literature. MedGenMed. 2006;8:2 pubmed
  20. Ozaki K, Oda H, Hatada K, Sakai K, Takahashi K, Miida T, et al. Highly vascular pelvic tumor causing high-output heart failure because of massive arteriovenous shunting: a case report. Circ J. 2003;67:554-5 pubmed
    ..This is a rare case of a highly vascular pelvic tumor causing high-output heart failure because of th massive arteriovenous shunting. ..
  21. Saluja K, Thomas J, Zhang S, Sturgis E, Jain K, Prieto V, et al. Malignant perivascular epithelioid cell tumor of the oropharynx with strong TFE3 expression mimicking alveolar soft part sarcoma: a case report and review of the literature. Hum Pathol. 2018;76:149-155 pubmed publisher
    ..and rearrangement, paucity of muscle and melanocytic marker expression, and morphologically mimicked alveolar soft part sarcoma. Awareness of this morphologic pitfall and recognition of TFE3 gene-rearranged PEComa, as a distinct ..
  22. Wang Y, Cui J, Yan X, Jin R, Hong X. Alveolar soft part sarcoma with multiple brain and lung metastases in pregnancy: A case report and literature review. Medicine (Baltimore). 2017;96:e8790 pubmed publisher
    ..Alveolar soft part sarcomas (ASPSs) with multiple brain metastases in pregnancy is a rare entity...
  23. Kim H, Lee H, Weon Y, Kim H. Alveolar soft-part sarcoma of the head and neck: clinical and imaging features in five cases. AJNR Am J Neuroradiol. 2005;26:1331-5 pubmed
  24. Morris W, Padgett D, Osborn F, Fleming J. Pathologic quiz case: an orbital mass in a 45-year-old woman. Alveolar soft part sarcoma. Arch Pathol Lab Med. 2005;129:534-6 pubmed
  25. Tornoczky T, Kalman E, Sapi Z, Orosz Z, Pajor L. Cytogenetic abnormalities of alveolar soft-part sarcomas using interphase fluorescent in situ hybridization: trisomy for chromosome 7 and monosomy for chromosomes 8 and 18 seem to be characteristic of the tumor. Virchows Arch. 2001;438:173-80 pubmed
    ..Most frequent and repeated numerical changes, which seem to be characteristic of the neoplasm and may play an important part in its pathogenesis and/or progression, were trisomy 7, monosomy 8 and monosomy 18. ..
  26. Guntupalli S, Anderson M, Bodurka D. Alveolar soft part sarcoma of the cervix: case report and literature review. Arch Gynecol Obstet. 2009;279:263-5 pubmed publisher
    b>Alveolar soft part sarcoma (ASPS) is a rare mesenchymal malignancy typically found in the extremities or chest of young adults...
  27. Yilmaz T, Kamani T, Sungur A. Alveolar soft part sarcoma on the glabella. Int J Pediatr Otorhinolaryngol. 2004;68:569-71 pubmed
    To present a paediatric case of alveolar soft part sarcoma on the glabella. A 10-year-old female patient with a slowly growing painful and pruritic mass between her brows...
  28. Bodi I, Gonzalez D, Epaliyange P, Gullan R, Fisher C. Meningeal alveolar soft part sarcoma confirmed by characteristic ASPCR1-TFE3 fusion. Neuropathology. 2009;29:460-5 pubmed publisher
    Sarcoma metastatic to the brain is uncommon and rarely occurs as the initial manifestation of tumor. Alveolar soft part sarcoma (ASPS) is a rare but well-studied subtype of sarcoma...
  29. Ju X, Sun K, Liu R, Li S, Abulajiang G, Zou H, et al. Exploring the Histogenesis and Diagnostic Strategy Using Immunoassay and RT-PCR in Alveolar Soft Part Sarcoma. Pathol Oncol Res. 2018;24:593-600 pubmed publisher
    b>Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma, but it's easily misdiagnosed in rare locations...
  30. Chaudhari P, Pathy S, Deo S, Chawla B, Mridha A. Alveolar soft part sarcoma of orbit: A rare diagnosis. J Egypt Natl Canc Inst. 2017;29:167-170 pubmed publisher
    b>Alveolar soft part sarcoma (ASPS) is an aggressive, rare tumour with unique morphological and histopathological features...
  31. Joyama S, Ueda T, Shimizu K, Kudawara I, Mano M, Funai H, et al. Chromosome rearrangement at 17q25 and xp11.2 in alveolar soft-part sarcoma: A case report and review of the literature. Cancer. 1999;86:1246-50 pubmed
    ..2;q25) in ASPS. The results of the current study indicate that further molecular analyses focused on 17q25 and Xp11.2 are of interest and could help to elucidate the pathogenesis of ASPS. ..
  32. Kumar A, Alrohmain B, Taylor W, Bhattathiri P. Alveolar soft part sarcoma: the new primary intracranial malignancy : A case report and review of the literature. Neurosurg Rev. 2017;: pubmed publisher
    ..The authors report their experience treating the eighth ostensible case of a primary intracranial alveolar soft part sarcoma (ASPS). A 21-year-old man presented to hospital after collapsing...
  33. Qiu L, Li Y, Ali S, Xie M. Alveolar soft part sarcoma occurring in the penis of a 3-year-old boy: A rare case report. Medicine (Baltimore). 2017;96:e8383 pubmed publisher
    b>Alveolar soft part sarcoma (ASPS) is a rare, malignant neoplasm, which mostly occurs in the upper and lower extremities. This article presents an unusual case of ASPS involving the penis of a 3-year-old boy...
  34. Khanna P, Paidas C, Gilbert Barness E. Alveolar soft part sarcoma: clinical, histopathological, molecular, and ultrastructural aspects. Fetal Pediatr Pathol. 2008;27:31-40 pubmed publisher
    b>Alveolar soft part sarcoma (ASPS) is a rare soft tissue tumor occurring mainly in the adolescents and young adults. Multimodality treatment has not been effective, and excision remains the mainstay of treatment...
  35. Ohno T, Park P, Higaki S, Miki H, Kamura S, Unno K. Smooth tubular aggregates associated with plasmalemmal invagination in alveolar soft part sarcoma. Ultrastruct Pathol. 1994;18:383-8 pubmed
    ..There was a possibility that the smooth tubular aggregate was a T-tubule-like structure, suggesting that the tumors were derived from skeletal muscle cells. ..
  36. Lopez Ferrer P, Jimenez Heffernan J, Vicandi B, Gonzalez Peramato P, Viguer J. Cytologic features of alveolar soft part sarcoma: report of three cases. Diagn Cytopathol. 2002;27:115-9 pubmed
    b>Alveolar soft part sarcoma (ASPS) is a rare, high-grade, epithelial-like sarcoma that shows characteristic histopathologic findings...
  37. Almansori M, Turner A, Girgis S, Vethanayagam D. Alveolar soft-part sarcoma presenting with eosinophilia and shunt. Can Respir J. 2005;12:389-91 pubmed
    ..The present article is the fourth report of eosinophilia in association with sarcoma, and the first involving ASPS. ..
  38. Park Y, Unni K, Kim Y, Han C, Yang M, Wenger D, et al. Primary alveolar soft part sarcoma of bone. Histopathology. 1999;35:411-7 pubmed
    b>Alveolar soft part sarcoma is a distinct, rare soft tissue tumour occurring primarily within the skeletal muscles or musculofascial planes in young adults. Primary involvement of bone is extremely rare...
  39. Yoshihiro T, Tsuchihashi K, Nio K, Arita S, Nakano T, Yasumatsu R, et al. Lingual alveolar soft part sarcoma responsive to pazopanib: A case report. Medicine (Baltimore). 2017;96:e8470 pubmed publisher
    ..tyrosine kinase inhibitors such as cediranib, sunitinib and pazopanib have been reported to be effective for alveolar soft part sarcoma (ASPS). The efficacy of pazopanib for the patient with lingual ASPS has yet to be reported.
  40. Khan A, Burke M. Alveolar soft-part sarcoma of the orbit. J Pediatr Ophthalmol Strabismus. 2004;41:245-6 pubmed
    ..The tumor and the contiguous medial rectus muscle in the left eye were excised and compensatory strabismus procedures were performed. Five years postoperatively, she has central binocular vision with no evidence of tumor recurrence...
  41. Gupta S, Jain S, Sodhani P. Alveolar soft part sarcoma: a rare entity with unique cytomorphological features. Cytopathology. 2003;14:40-1 pubmed
  42. Campbell B, Seymour J, Wheeler G, Sexton M. Alveolar soft-part sarcoma: a cardiac metastasis as a rare site of relapse. Am J Clin Oncol. 2006;29:422-3 pubmed
  43. Petersson F, Michal M. Minute alveolar soft part sarcoma of the endocervix: the smallest ever published case. Appl Immunohistochem Mol Morphol. 2009;17:553-6 pubmed publisher
    b>Alveolar soft part sarcoma (ASPS) is a distinctive mesenchymal tumor of uncertain histogenesis, which is exceedingly rare in the uterine cervix. We herein report the smallest (1...
  44. Tapisiz O, Gungor T, Ustunyurt E, Ozdal B, Bilge U, Mollamahmutoglu L. An unusual case of lingual alveolar soft part sarcoma during pregnancy. Taiwan J Obstet Gynecol. 2008;47:212-4 pubmed publisher
    We report a case of alveolar soft part sarcoma (ASPS) of the tongue that presented in the third trimester of pregnancy.
  45. Pang L, Roebuck D, Griffith J, Kumta S, Metreweli C. Alveolar soft-part sarcoma: a rare soft-tissue malignancy with distinctive clinical and radiological features. Pediatr Radiol. 2001;31:196-9 pubmed
    ..Two young females with ASPS presented with very vascular tumours in the thigh, with prominent intra- and extra-tumoural blood vessels. The imaging findings and the existing literature are reviewed...
  46. Kayton M, Delgado R, Busam K, Cody H, Athanasian E, Coit D, et al. Experience with 31 sentinel lymph node biopsies for sarcomas and carcinomas in pediatric patients. Cancer. 2008;112:2052-9 pubmed publisher
    ..Few data exist regarding techniques, indications, and outcomes for sentinel lymph node biopsy in pediatric patients with sarcomas and carcinomas...
  47. Hoon V, Thung S, Kaneko M, Unger P. HMB-45 reactivity in renal angiomyolipoma and lymphangioleiomyomatosis. Arch Pathol Lab Med. 1994;118:732-4 pubmed
    ..We discuss the widening spectrum of lesions that are reactive with HMB-45 and the relationship of angiomyolipoma and lymphangioleiomyomatosis...
  48. Madrigrano A, Beach B, Wheeler A, Wapnir I. Metastases to the breast: alveolar soft part sarcoma in adolescents. Clin Breast Cancer. 2008;8:92-3 pubmed publisher
    Metastases to the breast comprise 0.5%-2% of breast neoplasms. This is a case report of an 18-year-old woman with an alveolar soft part sarcoma metastatic to the breast.
  49. Shaddix K, Fakhre G, Nields W, Steers J, Hewitt W, Menke D. Primary alveolar soft-part sarcoma of the liver: anomalous presentation of a rare disease. Am Surg. 2008;74:43-6 pubmed
    ..We describe a 47-year-old woman with such a manifestation. Despite surgical resection and numerous chemotherapeutic regimens, this patient had widespread metastasis and died approximately 2 years after the diagnosis was established...
  50. Pang L, Li F, Chang B, Hu W, Lu T, Li X, et al. [Detection of ASPL-TFE3 fusion gene by reverse transcriptase polymerase chain reaction in paraffin-embedded tumor tissues of alveolar soft part sarcoma]. Zhonghua Bing Li Xue Za Zhi. 2004;33:508-12 pubmed
    To investigate the significance of detecting chimeric mRNA resulting from t(X;17)(p11.2;q25) in paraffin-embedded tumor tissues of alveolar soft part sarcoma (ASPS).
  51. Nair A, Pai D, Jagdish S, Krishnan R. Alveolar soft part sarcoma: a unique tumor with disputed histogenesis. Indian J Cancer. 2003;40:82-3 pubmed
  52. Genin O, Rechavi G, Nagler A, Ben Itzhak O, Nazemi K, Pines M. Myofibroblasts in pulmonary and brain metastases of alveolar soft-part sarcoma: a novel target for treatment?. Neoplasia. 2008;10:940-8 pubmed
    ..These results suggest that the myofibroblasts may serve as a novel target for treatment of ASPS metastases...
  53. Ordonez N, Mackay B. Alveolar soft-part sarcoma: a review of the pathology and histogenesis. Ultrastruct Pathol. 1998;22:275-92 pubmed
  54. Demir H, Berk F, Memisoglu K, Arslan A, Muezzinoglu B, Erdincler R, et al. "Double imaging" for the diagnostic work-up of alveolar soft part sarcoma with Tc-99m MIBI. Ann Nucl Med. 2002;16:151-5 pubmed
    ..A focus of dense accumulation of Tc-99m MIBI in the lungs, suggesting metastasis was also demonstrated...
  55. Lane J, Bowman P, Austin M, Sangueza O. Pathology quiz case 1. Alveolar soft part sarcoma (ASPS) of the tongue. Arch Otolaryngol Head Neck Surg. 2003;129:485, 487 pubmed
  56. Benetos I, Mavrogenis A, Soultanis K, Zoubos A, Papagelopoulos P, Soucacos P. Alveolar soft part sarcoma of the forearm: a case report. J Surg Orthop Adv. 2006;15:209-13 pubmed
    b>Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma that most commonly arises in the deep soft tissues of the lower extremities of adults. Median survival of patients with metastatic ASPS has been reported to be from 3 to 3...
  57. Rekhi B, Kumar R, Menon S, Medhi S, Desai S. Calvarial metastasis of a renal cell carcinoma, mimicking a primary alveolar soft part sarcoma, in a young girl-a rare case report. Pathol Oncol Res. 2009;15:137-41 pubmed publisher
    ..Biopsy examination showed overlapping features of an alveolar soft part sarcoma (ASPS) and a RCC...
  58. Kurtz J, Andres E, Rohr S, Maloisel F, Mechine A, Meyer C, et al. Pancreatic metastasis of alveolar soft-part sarcoma: a case report and review of the literature. Ann Oncol. 2001;12:865-7 pubmed
    ..Treatment consisted in subtotal pancreatoduodenectomy with pylorus resection. Both specific patterns of relapse and treatment opportunities of this uncommon feature are discussed...
  59. Charrier J, Esnault O, Brette M, Monteil J. Alveolar soft-part sarcoma of the cheek. Br J Oral Maxillofac Surg. 2001;39:394-7 pubmed
    ..We have also reviewed hypotheses about its aetiology...
  60. Kacerovska D, Michal M, Nemcova J, Vanecek T, Kreuzberg B, Mrazkova P, et al. Crystal-deficient alveolar soft-part sarcoma with cutaneous involvement: a case report. Am J Dermatopathol. 2009;31:272-7 pubmed publisher
    ..Molecular genetic study revealed fusion transcript ASPL-TFE3, type 2. To the best of our knowledge, cutaneous involvement of a crystal-deficient ASPS has not been reported...
  61. van Buren R, Stewart J. Alveolar soft part sarcoma presenting as a breast mass in a 13-year-old female. Diagn Cytopathol. 2009;37:122-4 pubmed publisher
    ..We report a clinically unsuspected case of alveolar soft part sarcoma (ASPS) presenting in the breast of a 13-year-old female...
  62. Sujit Kumar G, Chacko G, Chacko A, Rajshekhar V. Alveolar soft-part sarcoma presenting with multiple intracranial metastases. Neurol India. 2004;52:257-8 pubmed
    ..Computed Tomogram revealed multiple contrast enhancing intracranial lesions. Biopsy of one of the lesions was reported as metastatic alveolar soft part sarcoma. He was advised whole brain radiotherapy.
  63. Kashyap S, Sen S, Sharma M, Betharia S, Bajaj M. Alveolar soft-part sarcoma of the orbit: report of three cases. Can J Ophthalmol. 2004;39:552-6 pubmed
  64. Inci E, Korkut N, Erem M, Kalekoglu N. [Alveolar soft tissue sarcoma]. HNO. 2004;52:145-9 pubmed
    b>Alveolar soft part sarcoma is a malignant soft part tumor the etiology of which has not yet been clarified. Histopathological examinations show an alveolar or pseudoglandular pattern...
  65. Choi J, Goo J, Seo J, Kim H, Park C, Im J. Pulmonary metastases of alveolar soft-part sarcoma: CT findings in three patients. Korean J Radiol. 2000;1:56-9 pubmed
    ..On enhanced scans, some of the masses were seen to contain dilated and tortuous intratumoral vessels...
  66. Hanzer M, Nebl A, Spendel S, Pilhatsch A, Urban C, Benesch M. Necrosis of a skin autograft after short-term treatment with sunitinib in a 14-year-old girl with metastatic alveolar soft part sarcoma of the thigh. Klin Padiatr. 2010;222:184-6 pubmed publisher
    A 14-year-old girl was diagnosed with alveolar soft part sarcoma (ASPS) of the thigh and lung metastases. She underwent tumor resection and pulmonary metastasectomy followed by hyperfractionated local radiotherapy (44.8 Gy)...
  67. Aisner S, Beebe K, Blacksin M, Mirani N, Hameed M. Primary alveolar soft part sarcoma of fibula demonstrating ASPL-TFE3 fusion: a case report and review of the literature. Skeletal Radiol. 2008;37:1047-51 pubmed publisher
    b>Alveolar soft part sarcoma is a rare soft tissue tumor typically affecting young adults. These tumors are most often seen in the deep soft tissues of the extremities and patients generally present with advanced disease...
  68. Xu L, Yu S, Shao Y, Zhang H, Zhao Z. [Clinical features and prognosis of alveolar soft part sarcoma]. Zhonghua Zhong Liu Za Zhi. 2007;29:778-80 pubmed
    To investigate the clinical feature, suitable treatment and prognosis of alveolar soft part sarcoma.
  69. do Nascimento Souza K, Faria P, Costa I, Duriguetto A, Loyola A. Oral alveolar soft-part sarcoma: review of literature and case report with immunohistochemistry study for prognostic markers. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;99:64-70 pubmed
    ..To describe a case of alveolar soft-part sarcoma (ASPS) affecting the tongue of a child and to study prognostic imunohistochemical markers for the disease...
  70. Smythe J, Fink P, Logan G, Lees J, Rowe P, Alexander I. Human fibroblasts transduced with CD80 or CD86 efficiently trans-costimulate CD4+ and CD8+ T lymphocytes in HLA-restricted reactions: implications for immune augmentation cancer therapy and autoimmunity. J Immunol. 1999;163:3239-49 pubmed
    ..These results may have significant implications for the clinical implementation of this type of cancer immunotherapy and also raise questions about the possibility of trans-costimulating autoreactive T lymphocytes in vivo...
  71. Koguchi Y, Yamaguchi T, Yamato M, Osada D, Saotome K. Alveolar soft part sarcoma of bone. J Orthop Sci. 2005;10:652-5 pubmed
  72. Rossi G, Lucioni M, Sammarchi L, Paulli M, Beluffi G, Martini A, et al. Uncommon syndromes and treatment manifestations of malignancy: Case 1. Unusual association of lupus and sarcoma. J Clin Oncol. 2003;21:166-7 pubmed
  73. Xin F, Rana N, Ming Z, Lang Y. Alveolar soft part sarcoma of the retro peritoneum. J Cancer Res Ther. 2010;6:117-9 pubmed publisher
    b>Alveolar Soft Part Sarcoma (ASPS), also called Alveolar Soft-Tissue Sarcoma, is a rare type of soft-tissue neoplasm with a poor long term prognosis. Such tumors originating in the retro peritoneal space are extremely rare...
  74. Afshar A, Abbasi F. Photoclinic. Primary alveolar soft part sarcoma of bone. Arch Iran Med. 2006;9:175-6, 181 pubmed