muscle tissue neoplasms

Summary

Summary: Neoplasms composed of muscle tissue: skeletal, cardiac, or smooth. The concept does not refer to neoplasms located in muscles.

Top Publications

  1. Hannah C, Oliver D, Liu J. Fine needle aspiration biopsy and immunostaining findings in an aggressive inflammatory myofibroblastic tumor of the lung: a case report. Acta Cytol. 2007;51:239-43 pubmed
    ..Here we present FNA biopsy findings in conjunction with immunohistochemical studies in a case of primary and recurrent pulmonary IMT...
  2. Mueller B. Cancers in children infected with the human immunodeficiency virus. Oncologist. 1999;4:309-17 pubmed
    ..This article provides an overview of epidemiology and clinical and pathological presentations, as well as preliminary data regarding treatment options in children with HIV-associated malignancies...
  3. Koseoglu R, Ozkan N, Filiz N, Kayaoglu H, Aydin M, Culha E, et al. Intranodal palisaded myofibroblastoma; a case report and review of the literature. Pathol Oncol Res. 2009;15:297-300 pubmed publisher
    ..We present a 43-year-old-male patient with IPM and discuss histological, immunohistochemical features and pathogenesis of this rare benign neoplasm...
  4. Sacco O, Gambini C, Gardella C, Toma P, Rossi U, Jasonni V, et al. "Atypical steroid response" in a pulmonary inflammatory myofibroblastic tumor. Pediatr Pulmonol. 2010;45:721-6 pubmed publisher
    ..At thoracotomy, a well-circumscribed, multilobulated mass was partially resected and a diagnosis of IMT confirmed. Immunosuppression by corticosteroids may have favored the rapid progression of this apparently benign, indolent tumor...
  5. Gleizal A, Ranchere Vince C, Beziat J. Inflammatory myofibroblastic tumour of the tongue: a case report. Br J Oral Maxillofac Surg. 2007;45:423-4 pubmed
    ..Review of the original specimen with new immunohistochemical staining showed that it was an inflammatory fibroblastic tumour...
  6. Wang Y, Zhu H, Zhao H, Hei Y, Xiao L. [Diagnosis and management of the tumors of extraocular muscles]. Zhonghua Yan Ke Za Zhi. 2009;45:56-60 pubmed
    ..To evaluate the spectrum, clinical features, diagnostic methods and treatment of the tumors of extraocular muscles...
  7. Dasgupta D, Guthrie A, McClean P, Davison S, Luntley J, Rajwal S, et al. Liver transplantation for a hilar inflammatory myofibroblastic tumor. Pediatr Transplant. 2004;8:517-21 pubmed
    ..Successful management may include the need for liver transplantation...
  8. Miettinen M, Sobin L, Lasota J. True smooth muscle tumors of the small intestine: a clinicopathologic, immunhistochemical, and molecular genetic study of 25 cases. Am J Surg Pathol. 2009;33:430-6 pubmed publisher
    ..The number of LMS cases is too small for stratification for risk assessment. True SMTs of small intestine should be separated from GISTs because of different pathogenesis and treatment...
  9. Troncoso P, Ordonez N, Raymond A, Mackay B. Malignant granular cell tumor: immunocytochemical and ultrastructural observations. Ultrastruct Pathol. 1988;12:137-44 pubmed
    ..We report a malignant granular cell tumor of the subcutaneous tissue of the thigh in a 59-year-old man, and discuss the ultrastructural and immunocytochemical findings and their diagnostic value...

More Information

Publications62

  1. Porter G, Evans A, Lee A, Hamilton L, James J. Unusual benign breast lesions. Clin Radiol. 2006;61:562-9 pubmed
    ..Knowledge of these appearances may help confirm or refute radiological-pathological concordance of percutaneous biopsy results during multidisciplinary assessment of these lesions and aid patient management...
  2. Breen D, Dubus J, Chetaille B, Payan M, Dutau H. A rare cause of an endobronchial tumour in children: the role of interventional bronchoscopy in the diagnosis and treatment of tumours while preserving anatomy and lung function. Respiration. 2008;76:444-8 pubmed
  3. Jay A, Piper K, Farthing P, Carter J, Diwakar A. Low-grade myofibroblastic sarcoma of the tongue. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104:e52-8 pubmed
    ..The morphological, immunohistochemical, and electron microscopic features of this unusual sarcoma and the most likely differential diagnoses are discussed...
  4. Howman Giles R, London K, McCowage G, Graf N, Harvey J. Pulmonary inflammatory myofibroblastic tumor after Hodgkin's lymphoma and application of PET imaging. Pediatr Surg Int. 2008;24:947-51 pubmed publisher
    ..PET imaging with F(18)FDG was used in the initial diagnosis and has been used in follow-up after full surgical resection of the lesion...
  5. Nash J, Hessel A, Vigneswaran N, El Naggar A. Collagenous myofibroblastic tumor of the mandible: case report of a unique locally aggressive neoplasm. Head Neck Pathol. 2010;4:44-8 pubmed publisher
    ..At our 4 year follow-up, the patient remained free of local recurrence and surgery related complications. The clinicopathologic findings and the differential diagnosis of this lesion is presented and discussed...
  6. Raab C, Gartner J. Diagnosis of childhood cancer. Prim Care. 2009;36:671-84 pubmed publisher
    ..This optimally is performed by a skilled team: hematologist/oncologist, surgeon, radiologist, and pathologist. Best results depend upon early referral by the thoughtful practitioner...
  7. Griffin C, Hawkins A, Dvorak C, Henkle C, Ellingham T, Perlman E. Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors. Cancer Res. 1999;59:2776-80 pubmed
    ..We suggest that chromosomal rearrangements involving 2p23 near or within ALK are recurrent alterations in IMT and that ALK may have a novel role outside its previously recognized realm of lymphoid neoplasms...
  8. Magro G. Mammary myofibroblastoma: a tumor with a wide morphologic spectrum. Arch Pathol Lab Med. 2008;132:1813-20 pubmed publisher
  9. Kolli S, Ziaee A, Lee R, Lim M, Levy B, Labovitz A. Myofibroblastic sarcoma of mitral valve: a case report. J Am Soc Echocardiogr. 2005;18:285-6 pubmed
    ..We report a patient with symptoms of congestive heart failure whose workup revealed a myofibroblastic sarcoma of mitral valve...
  10. Ishida H, Konno K, Hamashima Y, Naganuma H, Komatsuda T, Ishida J, et al. Sonographic and color Doppler findings of gastrointestinal myogenic tumors with a marked extraluminal growth. Abdom Imaging. 1998;23:496-501 pubmed
    ..The mass of a jejunal leiomyoma case changed markedly in location under probe compression. Color Doppler sonography confirmed not only the hypervascular nature of the mass but also feeding and draining vessels...
  11. Corradi D, Bosio S, Maestri R, Mormandi F, Curry A, Eyden B. A giant myxoid mammary myofibroblastoma: evidence for a myogenic/synthetic phenotype and an extracellular matrix rich in fibronectin. Histopathology. 2008;52:396-9 pubmed
  12. Venkataraman S, Semelka R, Braga L, Danet I, Woosley J. Inflammatory myofibroblastic tumor of the hepatobiliary system: report of MR imaging appearance in four patients. Radiology. 2003;227:758-63 pubmed
    ..Because periportal infiltration is a common feature in both IMT and other malignant tumors of the porta hepatis, histologic examination should be considered before diagnosis and treatment...
  13. Miettinen M, Fetsch J. Evaluation of biological potential of smooth muscle tumours. Histopathology. 2006;48:97-105 pubmed
    ..This review summarizes the current knowledge, guidelines, prognostic data and controversies for the classification of SMTs of soft tissue and most visceral sites...
  14. Petersen M, Kuester D, Roessner A, Schutte K, Lippert H, Meyer F. [Exceptional bilocular inflammatory myofibroblastic pseudotumour (IMT) characterized by recurrent thoracic tumour growth and a rare (adult) second manifestation within the mesenteric tissue of the small intestine]. Z Gastroenterol. 2010;48:555-9 pubmed publisher
  15. Clerico A, Cappelli C, Ragni G, Caroli S, De Ioris M, Sordi A, et al. Evaluation of carboplatin pharmacokinetics in pediatric oncology by means of inductively coupled plasma mass spectrometry. Ann Ist Super Sanita. 2006;42:461-8 pubmed
  16. Hamidah A, Khu S, Thambidorai C, Muhaizan W, Zarina A, Jamal R. Recurrent gastric inflammatory myofibroblastic tumour in a 13-year-old male. Pediatr Surg Int. 2007;23:601-3 pubmed
    ..The patient has been recurrence-free for the past 2 years. Gastric IMT is an uncommon tumour in children with unpredictable prognosis...
  17. Khoddami M, Sanae S, Nikkhoo B. Rectal and appendiceal inflammatory myofibroblastic tumors. Arch Iran Med. 2006;9:277-81 pubmed
    ..Histologically, our cases had inflammatory myofibroblastic tumors very similar to that of other sites; the spindle cells were positive for vimentin and muscle-specific actin...
  18. Kubal C, Ghotkar S, Gosney J, Carr M. Pleural inflammatory myofibroblastoma: a locally aggressive intra-thoracic tumour. J Cardiothorac Surg. 2007;2:29 pubmed
    ..Semi-solid physical appearance of this tumour has not been reported previously. This case report further adds to the diagnostic dilemma related with this tumour...
  19. Kuroda N, Oonishi K, Iwamura S, Ohara M, Hirouchi T, Mizumo K, et al. Gastric carcinosarcoma with neuroendocrine differentiation as the carcinoma component and leiomyosarcomatous and myofibroblastic differentiation as the sarcomatous component. APMIS. 2006;114:234-8 pubmed
    ..Pathologists should bear in mind that gastric carcinosarcoma may show various types of differentiation...
  20. Jeon Y, Chang K, Suh Y, Jung H, Park S. Inflammatory myofibroblastic tumor of the central nervous system: clinicopathologic analysis of 10 cases. J Neuropathol Exp Neurol. 2005;64:254-9 pubmed
    ..Although our cases did not show ALK immunoreactivity, some IMTs-CNS can recur, which suggests the neoplastic potential of these tumors. The rearrangement of the ALK gene in IMTs-CNS should be verified by an examination of more cases...
  21. Cai K, Liu Y, Zhang B, Liu X, Xu Z, Mei J, et al. [Primary cardiac malignant tumor--report of 6 cases]. Zhonghua Bing Li Xue Za Zhi. 2004;33:294-6 pubmed
  22. Mattei P, Barnaby K. Rapid regression of duodenal inflammatory myofibroblastic tumor after intravenous ketorolac: case report and review of the literature. J Pediatr Surg. 2008;43:1196-9 pubmed publisher
    ..Ketorolac was administered intravenously after the biopsy and is implicated as a potential cause of the rapid regression of the tumor. We discuss the surgical management of this patient and present a review of the literature...
  23. Dall Igna P, Cecchetto G, Guglielmi M, Alaggio R. Clinical and pathologic considerations in a case of inflammatory myofibroblastic tumor of the spleen. Pediatr Surg Int. 2004;20:875-7 pubmed
  24. Sharma A, Sen A, Chaturvedi N, Yadav R. Myofibroblastoma of male breast: a case report. Indian J Pathol Microbiol. 2007;50:326-8 pubmed
    ..We present the case ofa 60 year male presenting with a left breast nodule, interpreted as gynaecomastia on cytology. Histopathology however revealed characteristicfeatures of a myofibroblastoma, confirmed by immunohistochemistry...
  25. Chen J, Xu Z, Zhao H, Dong D. [Distribution and differentiation of marrow mesenchymal cells in tumor tissue: experimental with rabbits]. Zhonghua Yi Xue Za Zhi. 2007;87:2361-4 pubmed
    ..To study the distribution of bone marrow mesenchymal stem cells (MSCs) in tumor tissue and the possibility of MSCs differentiating into myofibroblast under the induction of local tumor microenvironment...
  26. Patry G, Hovington H, LaRue H, Harel F, Fradet Y, Lacombe L. Tissue factor expression correlates with disease-specific survival in patients with node-negative muscle-invasive bladder cancer. Int J Cancer. 2008;122:1592-7 pubmed
    ..These patients could potentially benefit from adjuvant chemotherapy...
  27. Pucci A, Valori A, Muscio M, Garofalo L, Ferroni F, Abbruzzese P. Asymptomatic inflammatory myofibroblastic tumor of the heart: immunohistochemical profile, differential diagnosis, and review of the literature. Cardiovasc Pathol. 2009;18:187-90 pubmed publisher
    ..Because of their rarity in the heart, most knowledge is based on extracardiac lesions that have uncertain behaviour...
  28. Mackay B, Ordonez N, Salter J, Pollock R. Myofibroblastoma of the axilla. Ultrastruct Pathol. 1995;19:265-8 pubmed
    ..A diagnosis of myofibroblastoma was favored, although the possibility of a low-grade sarcoma could not be excluded. There has not been any indication of recurrence over a 4-month period of follow-up...
  29. Lee D, Suh Y, Lee S. Calcifying fibrous pseudotumour arising in a gastric inflammatory myofibroblastic tumour. Pathology. 2006;38:588-91 pubmed
  30. Sevinc A, Camci C. 'Time is a GIFT in GIST'--the medical and paramedical perspective of a case with metastatic gastrointestinal stromal tumor. Chemotherapy. 2009;55:11-4 pubmed publisher
    ..Interestingly, depression due to chemotherapy failure was also alleviated with imatinib. According to a recent study, median time to progression was 24 months, and overall survival was 57 months, reaching 5 years with imatinib...
  31. Chua C, Liu X, Gao J, Hamdy R, Chua B. Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells. Am J Physiol Heart Circ Physiol. 2006;290:H2606-13 pubmed
    ..Our results suggest that p53 stabilization is a focal point of Dox-induced apoptosis and that PFT-alpha interferes with multiple steps of Dox-induced apoptosis...
  32. Cessna M, Zhou H, Sanger W, Perkins S, Tripp S, Pickering D, et al. Expression of ALK1 and p80 in inflammatory myofibroblastic tumor and its mesenchymal mimics: a study of 135 cases. Mod Pathol. 2002;15:931-8 pubmed
    ..In IMT, immunohistochemistry for ALK1 and p80 is useful as an indicator of a 2p23 abnormality, but it must be interpreted in the context of histologic and other clinicopathologic data if used as an adjunct to differential diagnosis...
  33. Yamamoto H, Oda Y, Saito T, Sakamoto A, Miyajima K, Tamiya S, et al. p53 Mutation and MDM2 amplification in inflammatory myofibroblastic tumours. Histopathology. 2003;42:431-9 pubmed
  34. Lee K, Song K, Kwon Y, Lee I, Lee J, Lim T. Mesenchymal tumours of the thorax: CT findings and pathological features. Clin Radiol. 2003;58:934-44 pubmed
    ..Mesenchymal tumours tend to show protean and non-specific imaging characteristics. However, in some instances, the imaging characteristics of the tumour may allow a specific diagnosis to be made, such as with lipoid or vascular tumours...
  35. Applebaum H, Kieran M, Cripe T, Coffin C, Collins M, Kaipainen A, et al. The rationale for nonsteroidal anti-inflammatory drug therapy for inflammatory myofibroblastic tumors: a Children's Oncology Group study. J Pediatr Surg. 2005;40:999-1003; discussion 1003 pubmed
  36. Ko S, Shin S, Jeong Y. Mesenteric inflammatory myofibroblastic tumor mimicking a necrotized malignant mass in an adult: case report with MR findings. Abdom Imaging. 2005;30:616-9 pubmed
    ..To our knowledge, this is the first report of magnetic resonance imaging of mesenteric inflammatory myofibroblastic tumor with extensive central necrosis in an older patient...
  37. Gagne E, Su W. Congenital smooth muscle hamartoma of the skin. Pediatr Dermatol. 1993;10:142-5 pubmed
    ..A review of the approximately 50 cases reported in the literature showed that there is no known associated systemic involvement or malignant transformation. The clinical lesions usually become less prominent with time...
  38. Butler W, Cohen S, Squire R. Mesenchymal tumors of the mouse urinary bladder with vascular and smooth muscle differentiation. Toxicol Pathol. 1997;25:268-74 pubmed
    ..The histogenesis of the tumor is uncertain, but from its pleomorphic histological features, including smooth muscle and vascularity, it is probably derived from vascular mesenchyme...
  39. Pan C, Yu I, Yang A, Chiang H. Clear cell myomelanocytic tumor of the urinary bladder. Am J Surg Pathol. 2003;27:689-92 pubmed
    ..This case, in association with the expanding list of perivascular epithelioid cell tumor reported in different sites, suggests that this type of neoplasm may be ubiquitous...
  40. Yamaguchi U, Hasegawa T, Masuda T, Sekine S, Kawai A, Chuman H, et al. Differential diagnosis of gastrointestinal stromal tumor and other spindle cell tumors in the gastrointestinal tract based on immunohistochemical analysis. Virchows Arch. 2004;445:142-50 pubmed
  41. Yamagami K, Yoshioka K, Isaka Y, Inoue T, Hosoi M, Shakudo M, et al. A case of hypopituitarism due to inflammatory myofibroblastic tumor of the sella turnica. Endocr J. 2008;55:339-44 pubmed
    ..Although rare, IMT should be considered in the differential diagnosis of a sellar mass. Early treatment with corticosteroid therapy may reduce the risk of disease progression...
  42. Cerilli L. Multiple hepatic masses in a 38-year-old male 10 years after renal transplantation. Nephrol Dial Transplant. 2005;20:1756-8 pubmed
  43. Hara N, Kawaguchi M, Koike H, Nishiyama T, Takahashi K. Angiomyxoid tumor with an intermediate feature between cellular angiofibroma and angiomyofibroblastoma in the male inguinal region. Int J Urol. 2005;12:768-72 pubmed
  44. Poh C, Priddy R, Dahlman D. Intramandibular inflammatory myofibroblastic tumor--a true neoplasm or reactive lesion?. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100:460-6 pubmed
    ..The purpose of this study is to report the first intramandibular IMT and to discuss the possible nature of this lesion...
  45. Shintaku M, Fukushima A. Inflammatory myofibroblastic tumor of the uterus with prominent myxoid change. Pathol Int. 2006;56:625-8 pubmed
    ..Based on the immunoreactivity of tumor cells for ALK and h-caldesmon, the present tumor was considered inflammatory myofibroblastic tumor showing a focal phenotypic transition from myofibroblasts to smooth muscle cells...
  46. Polydorides A, Perry A, Edgar M. Large cell medulloblastoma with myogenic and melanotic differentiation: a case report with molecular analysis. J Neurooncol. 2008;88:193-7 pubmed publisher
  47. Jochum W, Hänggi D, Bruder E, Jeck T, Novotny H, Probst A, et al. Inflammatory myofibroblastic tumour of the sella turcica. Neuropathol Appl Neurobiol. 2004;30:692-5 pubmed
  48. Corapcioglu F, Kargi A, Olgun N, Ozer E, Olguner M, Sarialioglu F. Inflammatory myofibroblastic tumor of the ileocecal mesentery mimicking abdominal lymphoma in childhood: report of two cases. Surg Today. 2005;35:687-91 pubmed
    ..Because the choice of treatment for this tumor is conservative surgery, an accurate preoperative analysis is important to avoid any unnecessary aggressive surgical intervention or other therapeutic approaches...
  49. Ma Z, Hill D, Collins M, Morris S, Sumegi J, Zhou M, et al. Fusion of ALK to the Ran-binding protein 2 (RANBP2) gene in inflammatory myofibroblastic tumor. Genes Chromosomes Cancer. 2003;37:98-105 pubmed
    ..These findings expand the spectrum of ALK abnormalities observed in IMT and further confirm the clonal, neoplastic nature of these lesions...
  50. Varras M, Akrivis C, Demou A, Kitsiou E, Antoniou N. Angiomyofibroblastoma of the vagina in a postmenopausal breast cancer patient treated with tamoxifen: clinicopathologic analysis of a case and review of the literature. Int J Gynecol Cancer. 2006;16:581-5 pubmed
    ..The expression of estrogen and progesterone receptors suggests that it might arise as a neoplastic proliferation of hormonally responsible mesenchymal cells. Tamoxifen may exert stimuli effects upon mesenchymal cells...
  51. Cheema Z, Cannon T, Leech R, Brennan J, Adesina A, Brumback R. Medullomyoblastoma: case report. J Child Neurol. 2001;16:598-9 pubmed
    ..Although the histogenesis remains uncertain, advances in immunohistochemistry and electron microscopy suggest the origin of this tumor from a multipotential stem cell precursor...
  52. McMenamin M, Fletcher C. Mammary-type myofibroblastoma of soft tissue: a tumor closely related to spindle cell lipoma. Am J Surg Pathol. 2001;25:1022-9 pubmed
    ..Both mammary and extramammary lesions show morphologic overlap with spindle cell lipoma and are likely closely related...
  53. Kinoshita Y, Tajiri T, Ieiri S, Nagata K, Taguchi T, Suita S, et al. A case of an inflammatory myofibroblastic tumor in the lung which expressed TPM3-ALK gene fusion. Pediatr Surg Int. 2007;23:595-9 pubmed
    ..In addition to the histological diagnosis, the detection of the tumor specific fusion gene provided objective evidence in making a diagnosis...