fibroma

Summary

Summary: A benign tumor of fibrous or fully developed connective tissue.

Top Publications

  1. Torimitsu S, Nemoto T, Wakayama M, Okubo Y, Yokose T, Kitahara K, et al. Literature survey on epidemiology and pathology of cardiac fibroma. Eur J Med Res. 2012;17:5 pubmed publisher
    Although cardiac fibroma has been regarded as benign tumor, it presents various symptoms and may lead to death...
  2. Santos P, Nonaka C, Pinto L, de Souza L. Immunohistochemical expression of mast cell tryptase in giant cell fibroma and inflammatory fibrous hyperplasia of the oral mucosa. Arch Oral Biol. 2011;56:231-7 pubmed publisher
    ..In addition, the results suggest the involvement of mast cells in the induction of fibrosis and modulation of endothelial cell function in GCFs...
  3. Mosqueda Taylor A, Martínez Mata G, Carlos Bregni R, Vargas P, Toral Rizo V, Cano Valdez A, et al. Central odontogenic fibroma: new findings and report of a multicentric collaborative study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011;112:349-58 pubmed publisher
    The aim of this study was to describe the clinicopathologic and immunohistochemical characteristics of 14 cases of central odontogenic fibroma (COF), and the ultrastructural features of 2 of them.
  4. Nord K, Lilljebjörn H, Vezzi F, Nilsson J, Magnusson L, Tayebwa J, et al. GRM1 is upregulated through gene fusion and promoter swapping in chondromyxoid fibroma. Nat Genet. 2014;46:474-7 pubmed publisher
    ..evidence of aberrant glutamate signaling in the development of a locally aggressive bone tumor, chondromyxoid fibroma (CMF)...
  5. Knobloch K, Kuehn M, Vogt P. Focused extracorporeal shockwave therapy in Dupuytren's disease--a hypothesis. Med Hypotheses. 2011;76:635-7 pubmed publisher
  6. de Sousa S, Caldeira P, Grossmann S, de Aguiar M, Mesquita R. Desmoplastic fibroblastoma (collagenous fibroma): a case identified in the buccal mucosa. Head Neck Pathol. 2011;5:175-9 pubmed publisher
    ..Histopathology and immunohistochemistry staining studies were performed, and a diagnosis of the desmoplastic fibroblastoma was made. The patient has been disease-free for one year...
  7. Moretti V, de la Cruz M, Lackman R, Fox E. Fibroma of tendon sheath in the knee: a report of three cases and literature review. Knee. 2010;17:306-9 pubmed publisher
    b>Fibroma of tendon sheath (FTS) is a rare and benign soft-tissue tumor. It is predominantly found in the fingers, hands, and wrists of young, adult males. We describe a series of three cases all presenting in the atypical knee location...
  8. Haun D, Cho J, Kettner N. Symptomatic plantar fibroma with a unique sonographic appearance. J Clin Ultrasound. 2012;40:112-4 pubmed publisher
    We present a case of a solitary plantar fibroma with unique sonographic features with MRI and pathologic correlation. A 25-year-old woman presented with a left foot mass that interfered with her gait...
  9. Kim H, Jee W, Ryu K, Cho K, Suh J, Cho J, et al. MRI of chondromyxoid fibroma. Acta Radiol. 2011;52:875-80 pubmed publisher
    Chondromyxoid fibroma is a rare benign primary bone tumor of cartilage. Despite a characteristic radiographic appearance, chondromyxoid fibroma with atypical radiographic findings may mimic more common tumors.

More Information

Publications62

  1. Lin H, Chen H, Vu C, Yang H, Kuo R, Kuo Y, et al. Odontogenic fibroma: a clinicopathological study of 15 cases. J Formos Med Assoc. 2011;110:27-35 pubmed publisher
    Odontogenic fibroma (ODF) is a rare odontogenic tumor. It can be further divided into peripheral odontogenic fibroma (PODF) and central odontogenic fibroma (CODF)...
  2. Lee C, Kim S, Kim Y. Cardiac fibroma in an infant: complete resection after a Blalock-Taussig shunt as initial palliation. Ann Thorac Surg. 2010;90:1011-4 pubmed publisher
    ..This palliation allowed discharge from the hospital and provided good relief for the cyanosis until the tumor became resectable. The pathologic examination revealed a cardiac fibroma.
  3. Miyake C, del Nido P, Alexander M, Cecchin F, Berul C, Triedman J, et al. Cardiac tumors and associated arrhythmias in pediatric patients, with observations on surgical therapy for ventricular tachycardia. J Am Coll Cardiol. 2011;58:1903-9 pubmed publisher
    ..The aim of this study was to describe a large experience with primary cardiac tumors in pediatric patients, characterize associated arrhythmias, and expand knowledge of natural history and treatment options...
  4. Alaeddini M, Salehizadeh S, Baghaii F, Etemad Moghadam S. A retrospective analysis of peripheral odontogenic fibroma in an Iranian population. J Oral Maxillofac Surg. 2010;68:2099-103 pubmed publisher
    The aim of this study was to assess the relative frequency of peripheral odontogenic fibroma (POdF) in an Iranian population and to compare the obtained data with previous reports.
  5. Dahlin L, Ljungberg O. Dendritic fibromyxolipoma adherent to the median nerve in the forearm. J Plast Surg Hand Surg. 2012;46:120-3 pubmed publisher
    ..The tumour was successfully excised with no complications...
  6. Plaza J, Suster S, Prieto V, Sangueza M. Acquired reactive digital fibroma: a clinicopathologic report of 5 cases of a new entity. J Am Acad Dermatol. 2013;69:603-8 pubmed publisher
    ..Fibroblastic proliferations in the dermis comprise a heterogeneous group of disorders that can pose diagnostic challenges...
  7. Domenech A, de Arenaza D, Rivello H, Patrucco L, Bracco D. Surgery for papillary fibroelastoma with uncommon location in left ventricle. Asian Cardiovasc Thorac Ann. 2010;18:174-6 pubmed publisher
    ..A 59-year-old woman with 2 previous strokes presented with a tumor in the left ventricular apex. The patient underwent tumor resection through a left ventriculotomy. The histopathologic diagnosis was papillary fibroelastoma...
  8. Lee G, Suh K, Lee S, Lee S. Nuchal-type fibroma of the buttock: magnetic resonance imaging findings. Jpn J Radiol. 2010;28:538-41 pubmed publisher
    Nuchal-type fibroma, first described in 1988 by Enzinger and Weiss, is a rare fibrous growth occurring predominantly in the interscapular and paraspinous regions...
  9. Costa D, Alves A, Calasans Maia M, Cruz R, Lourenço S. Maxillary ameloblastic fibroma: a case report. Braz Dent J. 2011;22:171-4 pubmed
    Ameloblastic fibroma is a relatively rare benign odontogenic tumor in which both the epithelial and ectomesenchymal components are neoplastic...
  10. Kundangar R, Pandey V, Acharya K, Rao P, Rao L. An intraarticular fibroma of the tendon sheath in the knee joint. Knee Surg Sports Traumatol Arthrosc. 2011;19:1830-3 pubmed publisher
    ..Only five such cases in the knee joint have been reported so far. This is a case report of an intra-articular fibroma of the tendon sheath of the knee joint arising adjacent to posterior cruciate ligament (PCL)...
  11. Semczuk A, Skomra D, Gogacz M, Sliwinska J, Ciepliński K, Rechberger T. Synchronous adult-type granulosa cell tumor of the ovary with ovarian fibroma: a case report. Eur J Gynaecol Oncol. 2011;32:691-4 pubmed
    ..a case of a 73-year-old woman showing coexistence of adult-type granulosa cell tumor in one ovary with ovarian fibroma in the other...
  12. Shvartsbeyn M, Mason A, Bosenberg M, Ko C. Perifollicular fibroma in Birt-Hogg-Dubé syndrome: an association revisited. J Cutan Pathol. 2012;39:675-9 pubmed publisher
    ..indistinguishable from fibrofolliculoma/ trichodiscoma may show histopathologic findings of perifollicular fibroma or angiofibroma...
  13. Jacobs E, Witlox M, Hermus J. Fibroma of tendon sheath located within Kager's triangle. J Foot Ankle Surg. 2014;53:208-11 pubmed publisher
    The formation of a fibroma of the tendon sheath, a rare, slow-growing, benign tumor, usually occurs in the upper extremities of young adult males...
  14. Chen Y, Hsieh C, Eng H, Huang C. Ovarian fibroma in a 7-month-old infant: a case report and review of the literature. Pediatr Surg Int. 2004;20:894-7 pubmed
    Ovarian fibroma rarely occurs in prepubertal girls. We report an ovarian fibroma in a 7-month-old female infant presenting as a right abdominal mass...
  15. Cicconetti A, Bartoli A, Tallarico M, Maggiani F, Santaniello S. Central odontogenic fibroma interesting the maxillary sinus. A case report and literature survey. Minerva Stomatol. 2006;55:229-39 pubmed
    Odontogenic fibroma (OF) is a rare benign odontogenic tumor deriving from the dental mesenchymal tissue and accounting for less than 5% of all odontogenic tumors...
  16. Bossert T, Walther T, Vondrys D, Gummert J, Kostelka M, Mohr F. Cardiac fibroma as an inherited manifestation of nevoid basal-cell carcinoma syndrome. Tex Heart Inst J. 2006;33:88-90 pubmed
    ..was reconstructed after a partial ventriculectomy Histologic investigation showed a completely resected benign fibroma. The 30-year-old mother was known to have nevoid basal-cell carcinoma syndrome, which can be associated with ..
  17. Levanat S, Musani V, Komar A, Oreskovic S. Role of the hedgehog/patched signaling pathway in oncogenesis: a new polymorphism in the PTCH gene in ovarian fibroma. Ann N Y Acad Sci. 2004;1030:134-43 pubmed
    ..Loss of heterozygosity findings in the PTCH locus and increased expression of several genes in the pathway strongly suggest that the pathway is involved in both ovarian fibroma and dermoids.
  18. Stratemann S, Dzurik Y, Fish F, Parra D. Left ventricular cardiac fibroma in a child presenting with ventricular tachycardia. Pediatr Cardiol. 2008;29:223-6 pubmed
    ..a 7-year-old boy, with a first episode of symptomatic tachycardia, who was found to have a left ventricular (LV) fibroma. He had a normal echocardiogram prior to an electrophysiology study, which revealed a sustained monomorphic ..
  19. Shires C, Shete M, Thompson J. Management of suprastomal tracheal fibroma: introduction of a new technique and comparison with other techniques. Int J Pediatr Otorhinolaryngol. 2009;73:67-72 pubmed publisher
    Suprastomal tracheal granuloma/fibroma (SSTGF) is a common cause of failure to decannulate following pediatric tracheostomy. Because larger lesions obstruct the trachea, it is necessary to remove them prior to decannulation...
  20. Laskin W, Miettinen M, Fetsch J. Infantile digital fibroma/fibromatosis: a clinicopathologic and immunohistochemical study of 69 tumors from 57 patients with long-term follow-up. Am J Surg Pathol. 2009;33:1-13 pubmed publisher
    The clinicopathologic and immunohistochemical features of 69 pediatric examples of infantile digital fibroma/fibromatosis (IDF) were analyzed...
  21. Moustafa S, Sauvé C, Page P, Serri K. Incidental finding of a papillary fibroelastoma of the mitral valve chordae. Eur J Echocardiogr. 2008;9:745-6 pubmed publisher
    ..Owing to the risk of embolic complications, surgery was emergently performed with complete resection of the mass and preservation of the mitral valve. Histological evaluation confirmed the diagnosis of CPF...
  22. Parthenakis F, Nyktari E, Patrianakos A, Pitsis A, Asimaki A, Vardas P. Asymptomatic papillary fibroelastoma of the aortic valve in a young woman - a case report. Cardiovasc Ultrasound. 2009;7:43 pubmed publisher
    ..The importance of valve sparing tumour resection even in asymptomatic patients is emphasised...
  23. Ciatti R, Mariani P. Fibroma of tendon sheath located within the ankle joint capsule. J Orthop Traumatol. 2009;10:147-50 pubmed publisher
    We report a very rare case of fibroma of the tendon sheath arising from the anteromedial ankle joint capsule, with no apparent connection to any tendon in the area, found in a 58-year-old patient complaining of progressive local swelling...
  24. Campbell L, Petrick M. Mohs micrographic surgery for a problematic infantile digital fibroma. Dermatol Surg. 2007;33:385-7 pubmed
  25. Hsieh Y, Lin Y, Wu Y, Su H, Billings S, Hood A. Subungual pleomorphic fibroma. J Cutan Pathol. 2003;30:569-71 pubmed
    Pleomorphic fibroma is a benign fibroblastic tumor characterized by pleomorphic, hyperchromatic cells or giant multinucleated cells embedded in a collagenous stroma...
  26. Kitajima K, Kaji Y, Sugimura K. Usual and unusual MRI findings of ovarian fibroma: correlation with pathologic findings. Magn Reson Med Sci. 2008;7:43-8 pubmed
    ..We illustrate typical and atypical magnetic resonance (MR) imaging findings of ovarian fibromas and correlate them with histopathologic findings...
  27. Jhala D, Coventry S, Rao P, Yen F, Siegal G. Juvenile juxtacortical chondromyxoid fibroma of bone: a case report. Hum Pathol. 2008;39:960-5 pubmed publisher
    Conventional intramedullary chondromyxoid fibroma (CMF) is a rare benign tumor of bone; juxtacortical lesions are rarer still, and juxtacortical lesions occurring in children are heretofore essentially unreported...
  28. Gabbieri D, Rossi G, Bavutti L, Corghi F, Zacà F, Sarandria D, et al. Papillary fibroelastoma of the right atrium as an unusual source of recurrent pulmonary embolism. J Cardiovasc Med (Hagerstown). 2006;7:373-8 pubmed
    ..The case is unusual with respect to the site of origin of the papillary fibroelastoma as well as its clinical presentation, which is clearly related to pulmonary embolization...
  29. Smith C, Magenis R, Himoe E, Smith C, Mansoor A. Chondromyxoid fibroma of the nasal cavity with an interstitial insertion between chromosomes 6 and 19. Cancer Genet Cytogenet. 2006;171:97-100 pubmed
    Chondromyxoid fibroma is an uncommon benign cartilaginous tumor that rarely presents in the sino-nasal region as a locally destructive, erosive lesion...
  30. Mohammadi S, Martineau A, Voisine P, Dagenais F. Left atrial papillary fibroelastoma: a rare cause of multiple cerebral emboli. Ann Thorac Surg. 2007;84:1396-7 pubmed
    ..The microscopic examination demonstrated a papillary fibroelastoma. The unusual localization and management of papillary fibroelastomas are discussed...
  31. Fotiadis E, Akritopoulos P, Samoladas E, Akritopoulou K, Kenanidis E. Chondromyxoid fibroma: a rare tumor with an unusual location. Arch Orthop Trauma Surg. 2008;128:371-5 pubmed
    Chondromyxoid fibroma constitutes a rare benign tumor of the bones, which has a potential of regional enlargement towards the local tissues...
  32. Le Corroller T, Bouvier Labit C, Sbihi A, Champsaur P. Mineralized fibroma of the tendon sheath presenting as a bursitis. Skeletal Radiol. 2008;37:1141-5 pubmed publisher
    ..imaging-including ultrasound, computed tomography, and magnetic resonance imaging-and histological features of a fibroma of the tendon sheath with mineralized chondroid and osseous metaplasia, presenting as a semimembranosus bursitis...
  33. Alawi F, Freedman P. Sporadic sclerotic fibroma of the oral soft tissues. Am J Dermatopathol. 2004;26:182-7 pubmed
    Sclerotic fibroma (SF) is an uncommon, benign fibrous neoplasm that may present either as a sporadic, small, solitary cutaneous mass, in otherwise healthy individuals, or as solitary or multiple, discrete skin nodules in patients with ..
  34. Malghem J, Baudrez V, Lecouvet F, Lebon C, Maldague B, Vande Berg B. Imaging study findings in elastofibroma dorsi. Joint Bone Spine. 2004;71:536-41 pubmed
    ..When the lesion exhibits typical imaging features and produces no symptoms, as is usually the case, further investigations are probably unnecessary...
  35. De Cobelli F, Esposito A, Mellone R, Papa M, Varisco T, Besana R, et al. Images in cardiovascular medicine. Late enhancement of a left ventricular cardiac fibroma assessed with gadolinium-enhanced cardiovascular magnetic resonance. Circulation. 2005;112:e242-3 pubmed
  36. Vernon S, Casiano R. Sphenoid sinus chondromyxoid fibroma mimicking a mucocele. Am J Otolaryngol. 2006;27:406-8 pubmed
    We report the case of a 44-year-old man who presented with a chondromyxoid fibroma (CMF) of the sphenoid sinus, which filled the sinus and clinically and radiologically resembled a mucocele...
  37. Garcia B, Johann A, da Silveira Júnior J, Aguiar M, Mesquita R. Retrospective analysis of peripheral odontogenic fibroma (WHO-type) in Brazilians. Minerva Stomatol. 2007;56:115-9 pubmed
    The purpose of this study is to present data on a series of peripheral odontogenic fibroma, WHO (World Health Organization)-type (POF), in Brazilians and to compare the results with previously reported studies.
  38. Veras E, Santamaria I, Luna M. Sinonasal chondromyxoid fibroma. Ann Diagn Pathol. 2009;13:41-6 pubmed publisher
    Chondromyxoid fibroma (CMF) is a rare benign cartilaginous tumor that usually arises from the metaphysis of long bones. In rare cases, however, CMF presents in unusual locations, such as the facial bones and sinonasal tract...
  39. Aynaci O, Kerimoglu S, Ozturk C, Saracoglu M, Yildiz K. Intraarticular fibroma of the tendon sheath arising from the infrapatellar fat pad in the knee joint. Arch Orthop Trauma Surg. 2009;129:291-4 pubmed
    We report a rare case of fibroma of the tendon sheath arising from the fat pad in the knee. To our knowledge, only four previous cases of fibroma of the tendon sheath in the knee have been reported in the English literature...
  40. Law K, Phillips K, Cusimano R, Butany J. Multifocal "tapete" papillary fibroelastoma. J Clin Pathol. 2009;62:1066-70 pubmed publisher
    ..It is believed that this is the first reported instance of surgically resected and morphologically confirmed multiple PFEs seen and removed at one operation...
  41. Piazza N, Chughtai T, Toledano K, Sampalis J, Liao C, Morin J. Primary cardiac tumours: eighteen years of surgical experience on 21 patients. Can J Cardiol. 2004;20:1443-8 pubmed
    ..The literature on primary cardiac tumours is relatively limited because of their rare occurrence...
  42. Bicer M, Cikirikcioglu M, Pektok E, Muller H, Dettwiler S, Kalangos A. Papillary fibroelastoma of the left atrial wall: a case report. J Cardiothorac Surg. 2009;4:28 pubmed publisher
    ..The patient was treated surgically for the prevention of further embolic complications. Pertinent literature is also reviewed for this rare and benign cardiac tumor...
  43. Kaul P, Kay S, Gaines P, Suvarna S, Hopkinson D, Rocco G. Giant pleural fibroma with an abdominal vascular supply mimicking a pulmonary sequestration. Ann Thorac Surg. 2003;76:935-7 pubmed
    ..We believe this is the first case of solitary fibrous tumor of the pleura with a direct vascular supply from the abdominal aorta at the level of the renal arteries reported in the literature...
  44. Nocito A, Sarancone S, Bacchi C, Tellez T. Ovarian thecoma: clinicopathological analysis of 50 cases. Ann Diagn Pathol. 2008;12:12-6 pubmed publisher
    ..b>Fibroma and thecoma seem to be different neoplasms and should be considered distinct, separate entities because they have ..
  45. Cota C, Solivetti F, Kovacs D, Cristiani R, Amantea A. Elastofibroma dorsi: histologic and echographic considerations. Int J Dermatol. 2006;45:1100-3 pubmed
    ..The differential diagnosis includes frequently observed subcutaneous neoplasms such as lipoma, fibrolipoma or more aggressive tumors. The diagnosis is made with histologic examination...
  46. Parker W, Beckenbaugh R, Amrami K. Calcifying aponeurotic fibroma of the hand: radiologic differentiation from giant cell tumors of the tendon sheath. J Hand Surg Am. 2006;31:1024-8 pubmed
  47. Tarcoveanu E, Dimofte G, Niculescu D, Vasilescu A, Moldovanu R, Ferariu D, et al. Ovarian fibroma in the era of laparoscopic surgery: a general surgeon's experience. Acta Chir Belg. 2007;107:664-9 pubmed
    The ovarian fibroma is a rare benign tumor originating from the connective tissue of the ovarian cortex. On occasion, the general surgeon may encounter ovarian fibroma while operating an acute abdomen...
  48. Mahmood M, Salama M, Chaffins M, Ormsby A, Ma C, Linden M, et al. Solitary sclerotic fibroma of skin: a possible link with pleomorphic fibroma with immunophenotypic expression for O13 (CD99) and CD34. J Cutan Pathol. 2003;30:631-6 pubmed
    Solitary sclerotic fibroma (SF) presents as a well circumscribed dermal nodule, composed of sparse spindle cells with alternating wavy collagen fibers arranged in a storiform pattern...
  49. de Bree E, Zoetmulder F, Keus R, Peterse H, van Coevorden F. Incidence and treatment of recurrent plantar fibromatosis by surgery and postoperative radiotherapy. Am J Surg. 2004;187:33-8 pubmed
    ..The incidence of plantar fibromatosis (PF) is unknown. Sometimes PF tends to recur repetitively after surgical treatment. In our institute we have used postoperative radiotherapy in an attempt to diminish the change on recurrence...
  50. Domanski H, Carlén B, Sloth M, Rydholm A. Elastofibroma dorsi has distinct cytomorphologic features, making diagnostic surgical biopsy unnecessary: cytomorphologic study with clinical, radiologic, and electron microscopic correlations. Diagn Cytopathol. 2003;29:327-33 pubmed
    ..The current study suggests that the fine-needle aspiration (FNA) features are highly diagnostic, permitting a firm diagnosis of EFD in a typical clinical setting and eliminating the need for preoperative histologic examination...
  51. Hoffmann U, Globits S, Schima W, Loewe C, Puig S, Oberhuber G, et al. Usefulness of magnetic resonance imaging of cardiac and paracardiac masses. Am J Cardiol. 2003;92:890-5 pubmed
    ..Observers were accurate in the prediction of lesion type (area under curve 0.88 and 0.92), and there was good interobserver variability (Cohen's kappa = 0.64)...
  52. Shnayder Y, Greenfield B, Oweity T, DeLacure M. Malignant solitary fibrous tumor of the tongue. Am J Otolaryngol. 2003;24:246-9 pubmed
    ..Presentation, differential diagnosis, criteria for malignancy, treatment, and possible prognostic implications of this rare entity are discussed...
  53. Zidere V, Lubaua I, Lacis A. Giant fibroma of the right ventricle. Cardiol Young. 2002;12:584-6 pubmed
    ..We have successfully treated a 1-year old girl with a giant fibroma of the right ventricle using the principles of the Batista procedure...