fibrous tissue neoplasms

Summary

Summary: Neoplasms composed of fibrous tissue, the ordinary connective tissue of the body, made up largely of yellow or white fibers. The concept does not refer to neoplasms located in fibrous tissue.

Top Publications

  1. Fletcher C, Dal Cin P, De Wever I, Mandahl N, Mertens F, Mitelman F, et al. Correlation between clinicopathological features and karyotype in spindle cell sarcomas. A report of 130 cases from the CHAMP study group. Am J Pathol. 1999;154:1841-7 pubmed
    ..There is a clear need to further study and understand the significance of multiple chromosomal abnormalities in this group of mesenchymal neoplasms with the particular goal of determining their role in the process of tumor development...
  2. Piattelli A, Fioroni M, Rubini C. Solitary fibrous tumour of the tongue. Oral Oncol. 1998;34:431-4 pubmed
    ..The differential diagnosis must be made from many soft tissue tumours. SFTs stain strongly, in almost all cases, for CD34...
  3. Tihan T, Viglione M, Rosenblum M, Olivi A, Burger P. Solitary fibrous tumors in the central nervous system. A clinicopathologic review of 18 cases and comparison to meningeal hemangiopericytomas. Arch Pathol Lab Med. 2003;127:432-9 pubmed
    ..In particular, densely cellular regions seen in some SFTs can be indistinguishable from HPC. Little is known about the biological behavior of SFTs, although most seem amenable to total resection...
  4. Yamashita Y, Satoh T, Goto M. Solitary fibrous tumour of the tongue: a case report with immunohistochemical studies. Int J Oral Maxillofac Surg. 2002;31:681-3 pubmed
    ..We report here case of SFT arising from the tongue of a 75-year-old woman. To our knowledge, this is the second case reported of SFT originating from the tongue...
  5. Alexander M, Yang S, Yung R, Brasic J, Pannu H. Diagnosis of benign solitary fibrous tumors by positron emission tomography. South Med J. 2004;97:1264-7 pubmed
    ..FDG PET has high sensitivity, specificity, positive predictive value, and negative predictive value in the diagnostic clarification of radiologically indeterminate pulmonary lesions...
  6. Ide F, Saito I. Oral solitary fibrous tumour. Oral Dis. 2002;8:314-5 pubmed
  7. Rodriguez I, Ayala E, Caballero C, de Miguel C, Matias Guiu X, Cubilla A, et al. Solitary fibrous tumor of the thyroid gland: report of seven cases. Am J Surg Pathol. 2001;25:1424-8 pubmed
    ..The cumulative data of 13 cases (comprised of the seven present cases and the six previously reported) suggest a benign clinical behavior for thyroid SFT...
  8. Vossough A, Torigian D, Zhang P, Siegelman E, Banner M. Extrathoracic solitary fibrous tumor of the pelvic peritoneum with central malignant degeneration on CT and MRI. J Magn Reson Imaging. 2005;22:684-6 pubmed
  9. Hardisson D, Cuevas Santos J, Contreras F. Solitary fibrous tumor of the skin. J Am Acad Dermatol. 2002;46:S37-40 pubmed
    ..Recognition of SFT in the skin is important to avoid possible confusion with a variety of spindle cell neoplasms with different biologic potential...

More Information

Publications62

  1. Vargas P, Alves F, Lopes M, Siqueira S, Menezes L, Aldred V, et al. Solitary fibrous tumour of the mouth: report of two cases involving the tongue and cheek. Oral Dis. 2002;8:111-5 pubmed
    ..Diagnosis of SFT is difficult and, although uncommon, it should be considered in the differential diagnosis of oral soft tissue tumours...
  2. Fiorello A, Vicidomini G, Pastore V, Santini M. An enormous asymptomatic solitary fibrous tumour of the pleura. Eur J Cardiothorac Surg. 2006;30:939 pubmed
  3. Morita R, Nakamura S, Kaneko K, Suga M, Kyo S. [A resected case of solitary fibrous tumor of the pleura]. Kyobu Geka. 2002;55:181-3 pubmed
    ..From these immunohistochemical stainings and microscopic findings, the tumor was diagnosed as SFT. An immunohistochemical study of the tumor seems to be very useful for the diagnosis of SFT...
  4. Magro G. Stromal tumors of the lower female genital tract: histogenetic, morphological and immunohistochemical similarities with the "benign spindle cell tumors of the mammary stroma". Pathol Res Pract. 2007;203:827-9 pubmed
  5. Kurtkaya O, Elmaci I, Sav A, Pamir M. Spinal solitary fibrous tumor: seventh reported case and review of the literature. Spinal Cord. 2001;39:57-60 pubmed
    ..Solitary fibrous tumors have been found in a variety of locations suggesting that a solitary fibrous tumor has a mesenchymal origin. This rare tumor should be considered in the differential diagnosis of spinal tumors...
  6. Priola A, Priola S, Cataldi A, Ferrero B, Garofalo G, Errico L, et al. CT-guided percutaneous transthoracic biopsy in the diagnosis of mediastinal masses: evaluation of 73 procedures. Radiol Med. 2008;113:3-15 pubmed publisher
    ..This study was performed to evaluate the factors affecting the diagnostic accuracy and rate of complications of CT-guided percutaneous transthoracic needle biopsy of mediastinal masses...
  7. Ganly I, Patel S, Stambuk H, Coleman M, Ghossein R, Carlson D, et al. Solitary fibrous tumors of the head and neck: a clinicopathologic and radiologic review. Arch Otolaryngol Head Neck Surg. 2006;132:517-25 pubmed
    ..To describe the clinicopathologic and radiologic features of solitary fibrous tumors of the head and neck...
  8. Poyraz A, Kilic D, Hatipoglu A, Bakirci T, Bilezikci B. Pedunculated solitary fibrous tumours arising from the pleura. Monaldi Arch Chest Dis. 2006;65:165-8 pubmed
    ..The aim is to summarise our experience in the management of solitary fibrous tumour...
  9. Okada S, Ebihara Y, Kudo M, Serizawa H, Shimizu T, Otani M, et al. Scratch cytologic findings on surgically resected solitary fibrous tumors of the pleura. Acta Cytol. 2001;45:372-80 pubmed
    ..To ascertain the cytologic characteristics of solitary fibrous tumors of the pleura (SFTPs) on smear preparations...
  10. Caroli E, Salvati M, Orlando E, Lenzi J, Santoro A, Giangaspero F. Solitary fibrous tumors of the meninges: report of four cases and literature review. Neurosurg Rev. 2004;27:246-51 pubmed
    ..It is important that every new case of meningeal SFT be reported to throw light on this particular tumor and to affirm its status as a clinicopathological entity...
  11. Kim K, Gonzalez I, McComb J, Giannotta S. Unusual presentations of cerebral solitary fibrous tumors: report of four cases. Neurosurgery. 2004;54:1004-9; discussion 1009 pubmed
    ..Nine years after its debulking from the posterior fossa, one tumor disseminated to the spine, lung, and liver. Only one such aggressive C-SoFT has been described previously...
  12. Alvarado Cabrero I, Hernandez S, Kelly G J, Cuenca Buele S. [Pleura's solitary fibrous tumor. Clinical pathology analysis of 17 cases]. Rev Med Inst Mex Seguro Soc. 2006;44:397-402 pubmed
    ..The objective of this study is to present 17 new cases of SFTP and analyze the morphological characteristics that help to identify tumors with a malignant behavior...
  13. Scarsbrook A, Evans A, Slade M, Gleeson F. Recurrent solitary fibrous tumour of the pleura due to tumour seeding following ultrasound-guided transthoracic biopsy. Clin Radiol. 2005;60:130-2 pubmed
  14. Campbell N, Antippa P. Solitary fibrous tumour of the pleura. Heart Lung Circ. 2006;15:400-1 pubmed
    ..We present a case of a solitary fibrous tumour, which presented with clubbing...
  15. Cuadrado M, Garcia Camarero T, Exposito V, Val Bernal J, Gomez Roman J, Garijo M. Cardiac intracavitary metastasis of a malignant solitary fibrous tumor: case report and review of the literature on sarcomas with left intracavitary extension. Cardiovasc Pathol. 2007;16:241-7 pubmed
    ..Solitary fibrous tumor (SFT) of the pleura with malignant progression occurs uncommonly. Cardiac intracavitary extension of tumors is rarely seen, with left side location being exceptional...
  16. Yamada H, Tsuzuki T, Yokoi K, Kobayashi H. Solitary fibrous tumor of the kidney originating from the renal capsule and fed by the renal capsular artery. Pathol Int. 2004;54:914-7 pubmed
    ..The origin of SFT of the kidney remains uncertain. The tumor in this case merged with the renal capsule and was fed by the renal capsular artery, which suggests that some SFT of the kidney originate from the renal capsule...
  17. Seebus E, Vrugt B, de Jong R, Aalbers R. A 71-yr-old male with increasing dyspnoea, cough and an intrathoracic mass. Eur Respir J. 2003;22:1042-5 pubmed
  18. Jeong A, Lee H, Kim S, Cho K. Solitary fibrous tumor of the parapharyngeal space: MR imaging findings. AJNR Am J Neuroradiol. 2002;23:473-5 pubmed
    ..It mimicked a tumor originating from the deep lobe of the parotid gland...
  19. Bonomo L, Feragalli B, Sacco R, Merlino B, Storto M. Malignant pleural disease. Eur J Radiol. 2000;34:98-118 pubmed
  20. Kristensen P, Petersen R, Hansen P. [Spontaneous hemothorax from a fibrous pleural tumour in an expectant father. Is the delivery room a dangerous place for men?]. Ugeskr Laeger. 2007;169:1325-6 pubmed
    ..This unusual presentation with severe bleeding from a pleural tumour was most probably initiated by the expectant father's excitement during his wife's labour...
  21. Hong J, Chung Y, Kim S, Kim T, Lee K. Solitary fibrous tumour of the face: a rare case report. Br J Plast Surg. 2002;55:75-7 pubmed
    ..This rare location of an uncommon lesion can lead to a confusing diagnosis. We report a case of solitary fibrous tumour originating in the temporal region of the face, and call for awareness of this tumour among plastic surgeons...
  22. Salah M, Haha Bellil S, Mekni A, Bellil K, Chelly I, Kchir N, et al. [Unusual tumour of the parotid gland]. Ann Pathol. 2006;26:289-90 pubmed
  23. Kanamori Y, Hashizume K, Sugiyama M, Motoi T, Fukayama M, Ida K, et al. Intrapulmonary solitary fibrous tumor in an eight-year-old male. Pediatr Pulmonol. 2005;40:261-4 pubmed
    ..e., CD34 expression on the tumor cells. The SFT reported here is an extremely rare phenotype in two respects: it originated in a child under age 10 years, and it expanded in an intrapulmonary fashion...
  24. Papi G, Corrado S, Ruggiero C, LiVolsi V. Solitary fibrous tumor of the thyroid gland associated with papillary thyroid carcinoma. Thyroid. 2006;16:319-20 pubmed
  25. Milenkovic B, Stojsic J, Dudvarski A, Bosnjak Petrović V, Ercegovac M. [Benign solitary fibrous pleural tumour and hypoglycaemia]. Srp Arh Celok Lek. 2007;135:326-9 pubmed
    ..Solitary fibrous tumours of the pleura are uncommon and discovered fortuitously or in patients with non-specific respiratory symptoms. When associated with hypoglycaemia, they are commonly referred to as Doege-Potter syndrome...
  26. Balduyck B, Lauwers P, Govaert K, Hendriks J, De Maeseneer M, Van Schil P. Solitary fibrous tumor of the pleura with associated hypoglycemia: Doege-Potter syndrome: a case report. J Thorac Oncol. 2006;1:588-90 pubmed
    ..After surgical removal, the hypoglycemia resolved. Solitary fibrous tumors are localized tumors of the pleura with an unpredictable behavior. The therapy consists of resection...
  27. Magro G, Cavallaro V, Torrisi A, Lopes M, Dell Albani M, Lanzafame S. Intrarenal solitary fibrous tumor of the kidney report of a case with emphasis on the differential diagnosis in the wide spectrum of monomorphous spindle cell tumors of the kidney. Pathol Res Pract. 2002;198:37-43 pubmed
  28. Tateishi U, Nishihara H, Morikawa T, Miyasaka K. Solitary fibrous tumor of the pleura: MR appearance and enhancement pattern. J Comput Assist Tomogr. 2002;26:174-9 pubmed
    ..The aim of the current study was to characterize the MR appearance of solitary fibrous tumor of the pleura (SFTP)...
  29. Weiss B, Horton D. Preoperative embolization of a massive solitary fibrous tumor of the pleura. Ann Thorac Surg. 2002;73:983-5 pubmed
    ..We recommend preoperative angiography for massive chest tumors that may be vascular and require piecemeal removal for total excision...
  30. Mangat A, Schiller C, Mengoni P, Reynolds C, Jeruss J. Calcifying fibrous pseudotumor of the breast. Breast J. 2009;15:299-301 pubmed publisher
    ..We present the first reported case of a CFP in the breast. CFP should be considered in the differential diagnosis for patients presenting with coarse indeterminate calcifications of the breast...
  31. Roccia F, Tavolaccini A, Daniele D, Berrone S. Enlarging lesion of the upper eyelid. J Oral Maxillofac Surg. 2006;64:943-8 pubmed
  32. Gambini C, Rongioletti F. Glial choristoma of the tongue. Am J Dermatopathol. 2005;27:360-1 pubmed
  33. Hara M, Kume M, Oshima H, Shibamoto Y, Iida A, Mori Y, et al. F-18 FDG uptake in a malignant localized fibrous tumor of the pleura. J Thorac Imaging. 2005;20:118-9 pubmed
    ..It was suggested that FDG-PET is helpful to know which parts of lesions are benign or malignant in patients with LFTP whose prognoses are usually difficult to predict...
  34. Xambre L, Lages R, Cerqueira M, Silva V, Prisco R, Santos R, et al. [Solitary fibrous tumor. Two additional cases with urologic implications]. Actas Urol Esp. 2003;27:832-8 pubmed
    ..The second tumour was located in the spermatic cord. A review of the theme is presented based on the available literature...
  35. Cameselle Teijeiro J, Manuel Lopes J, Villanueva J, Gil Gil P, Sobrinho Simoes M. Lipomatous haemangiopericytoma (adipocytic variant of solitary fibrous tumour) of the thyroid. Histopathology. 2003;43:406-8 pubmed
  36. Hashimoto D, Inoue H, Ohbayashi C, Nibu K. Solitary fibrous tumor in the parapharyngeal space. Otolaryngol Head Neck Surg. 2006;134:535-6 pubmed
  37. Piana S, Putrino I, Cavazza A, Nigrisoli E. Solitary fibrous tumor of the spinal nerve rootlet: report of a case mimicking schwannoma. Arch Pathol Lab Med. 2004;128:335-7 pubmed
    ..The present case suggests that solitary fibrous tumor should be considered in differentiating spindle cell lesions of the spinal cord and nerve rootlet...
  38. Minhas K, Barakzai A, Qureshi A. Fibromatous periorchitis. J Pak Med Assoc. 2009;59:47-9 pubmed
    ..Clinically these lesions mimic malignancy resulting in the treatment by radical orchidectomy. Fibrous pseudotumours should be considered in differential diagnosis when one encounters a predominantly fibrocollagenous lesion...
  39. Ogawa K, Tada T, Takahashi S, Sugiyama N, Inaguma S, Takahashi S, et al. Malignant solitary fibrous tumor of the meninges. Virchows Arch. 2004;444:459-64 pubmed
    ..1+/-6.4% and 6/10HPF in the last (5th) one, respectively. Thus, the present case suggests that meningeal SFTs possess malignant potential so that careful long-term follow up is required...
  40. Lo Muzio L, Mascolo M, Capodiferro S, Favia G, Maiorano E. Solitary fibrous tumor of the oral cavity: the need for an extensive sampling for a correct diagnosis. J Oral Pathol Med. 2007;36:538-42 pubmed
    ..Histologically, SFT may show wide morphological variability of both its cellular and stromal components, which may lead to incorrect diagnosis especially when dealing with small incisional biopsies...
  41. Yamashita S, Tochigi T, Kawamura S, Aoki H, Tateno H, Kuwahara M. Case of retroperitoneal solitary fibrous tumor. Hinyokika Kiyo. 2007;53:477-80 pubmed
    ..The tumor has malignant potential with partially increased mitotic activity and cellularity in the histological examination. The patient is healthy and without evidence of recurrence or metastasis 26 months from surgery...
  42. Yajima S, Fukutomi T, Akashi Tanaka S, Nanasawa T, Miyakawa K, Hasegawa T. Diabetic mastopathy: a case report with reference to the findings of enhanced computed tomography. Breast Cancer. 2001;8:246-9 pubmed
    ..Physicians should be aware of the association of long-standing diabetes mellitus with the development of fibrous mastopathy. CT is considered a useful tool to differentiate diabetic mastopathy from breast cancer...
  43. Vennarecci G, Ettorre G, Giovannelli L, Del Nonno F, Perracchio L, Visca P, et al. Solitary fibrous tumor of the liver. J Hepatobiliary Pancreat Surg. 2005;12:341-4 pubmed
    ..Surgeons must be aware of SFT of the liver, and this neoplasm should be included in the differential diagnosis of a single large hepatic mass...
  44. de Leval L, Defraigne J, Hermans G, Dôme F, Boniver J, Herens C. Malignant solitary fibrous tumor of the pleura: report of a case with cytogenetic analysis. Virchows Arch. 2003;442:388-92 pubmed
    ..Demonstration of a recurrent abnormal karyotype largely supports its relevance to the malignant clone and suggests a role of supernumerary chromosome(s) 8 in the determinism of malignant behavior in SFT...
  45. Sa G, Bonneville F, Poirier J, Lopes M, Dormont D, Chiras J. Giant solitary fibrous tumour of the meninges: MR-pathological correlation. J Neuroradiol. 2006;33:343-6 pubmed
    ..These two components were also identifiable on the pathological examination, allowing an interesting imaging-histological correlation. Differential diagnoses of this rare extra-axial lesion are discussed...
  46. Alobid I, Alos L, Maldonado M, Menéndez L, Bernal Sprekelsen M. Laryngeal solitary fibrous tumor treated with CO2 laser excision: case report. Eur Arch Otorhinolaryngol. 2005;262:286-8 pubmed
    ..The tumor was removed by transoral CO(2) laser surgery. The definitive diagnosis was obtained by immunohistochemical analysis that showed vimentin and CD34-positive cells. The patient remains free of tumor after 15 months of follow-up...
  47. Kumagai M, Suzuki H, Takahashi E, Matsuura K, Furukawa M, Suzuki H, et al. A case of solitary fibrous tumor of the parotid gland: review of the literatures. Tohoku J Exp Med. 2002;198:41-6 pubmed
    ..Her post-operative course was uneventful, and she is currently free from disease 14 months after surgery. Diagnosis, clinical behavior and treatment of solitary fibrous tumor are reviewed from perusal of the literature...
  48. Rougemont A, Fetni R, Murthy S, Fournet J. A complex translocation (6;12;8)(q25;q24.3;q13) in a fibrous hamartoma of infancy. Cancer Genet Cytogenet. 2006;171:115-8 pubmed
    ..3;q13). This case represents the second cytogenetic analysis reported to date in fibrous hamartoma of infancy and reveals a different translocation than the reciprocal translocation t(2;3)(q31;q21) previously reported...
  49. Gonzalez Garcia R, Gil Diez Usandizaga J, Hyun Nam S, Rodriguez Campo F, Naval Gias L. Solitary fibrous tumour of the oral cavity with histological features of aggressiveness. Br J Oral Maxillofac Surg. 2006;44:543-5 pubmed
    ..The tumour cells were strongly stained for CD34. There has been no recurrence after 18 months...
  50. Letson G, Muro Cacho C. Genetic and molecular abnormalities in tumors of the bone and soft tissues. Cancer Control. 2001;8:239-51 pubmed
    ..This article provides a comprehensive review of the cytogenetic abnormalities observed in bone and soft-tissue tumors, emphasizing known downstream molecular changes that may play a role in oncogenesis...
  51. Wang H, Zhang W, Yan L, Yao H, Ding W, Yu X. Clinical pathological analysis and immunohistochemical study of ten solitary fibrous tumors. Chin Med J (Engl). 2002;115:1412-4 pubmed
    ..To study the clinical and pathological characteristics of solitary fibrous tumor (SFT)...
  52. Matsushita S, Uemura T, Sugihara H, Hashimoto H, Tanabe T, Saito T, et al. A solitary fibrous tumor arising in the perioral region. J Dermatol. 2005;32:1041-3 pubmed
  53. Kyriafinis G, Constantinidis J, Karkavelas G, Triaridis S, Daniilidis J. [Solitary fibrous tumor of the nose and paranasal sinuses]. HNO. 2006;54:962-6 pubmed
    ..The solitary fibrous tumor is an uncommon, benign lesion with a mesenchymal origin which arises most commonly from the pleura and, in extremely rare cases, from the mucosa of the nose and paranasal sinuses...