osteoid osteoma


Summary: Benign circumscribed tumor of SPONGY BONE occurring especially in the bones of the extremities and vertebrae, most often in young persons.

Top Publications

  1. Mastrantuono D, Martorano D, Verna V, Mancini A, Faletti C. Osteoid osteoma: our experience using radio-frequency (RF) treatment. Radiol Med. 2005;109:220-8 pubmed
    To present the results of two years experience with a minimally invasive radio-frequency technique designed by our team in the treatment of osteoid osteoma.
  2. Giombini A, Dragoni S, Averna T, Ripani M, Longo U, Maffulli N. Osteoid osteoma mimicking overuse syndromes in athletes. J Sports Med Phys Fitness. 2009;49:167-70 pubmed
    ..the clinical features, findings at imaging, management and outcome of five athletes who presented with osteoid osteoma. The diagnosis was missed initially in all the athletes, who were managed for an overuse syndrome for many ..
  3. De Praeter M, Dua G, Seynaeve P, Vermeersch D, Klaes R. Occipital pain in osteoid osteoma of the atlas. A report of two cases. Spine (Phila Pa 1976). 1999;24:912-4 pubmed
    Two cases of occipital pain caused by an osteoid osteoma of the atlas are presented.
  4. Yip P, Lam Y, Chan M, Shu J, Lai K, So Y. Computed tomography-guided percutaneous radiofrequency ablation of osteoid osteoma: local experience. Hong Kong Med J. 2006;12:305-9 pubmed
    b>Osteoid osteoma is a slow-growing tumour with limited growth potential. In the past, treatment comprised open surgery with en-bloc resection or curettage of the tumour...
  5. Peyser A, Applbaum Y, Khoury A, Liebergall M, Atesok K. Osteoid osteoma: CT-guided radiofrequency ablation using a water-cooled probe. Ann Surg Oncol. 2007;14:591-6 pubmed
    The purpose of this study was to assess the safety and efficacy of computed tomography (CT) guided percutaneous radiofrequency (RF) ablation of osteoid osteoma by using the water-cooled probe.
  6. Akhlaghpoor S, Tomasian A, Arjmand Shabestari A, Ebrahimi M, Alinaghizadeh M. Percutaneous osteoid osteoma treatment with combination of radiofrequency and alcohol ablation. Clin Radiol. 2007;62:268-73 pubmed
    To assess the efficacy of percutaneous osteoid osteoma treatment using a combination of radiofrequency ablation (RFA) and alcohol ablation with regard to technical and long-term clinical success.
  7. Kan P, Schmidt M. Osteoid osteoma and osteoblastoma of the spine. Neurosurg Clin N Am. 2008;19:65-70 pubmed
    ..The authors review the clinical presentation, radiologic findings, and treatment in osteoid osteoma and osteoblastoma of the spine, with an emphasis on surgical management and outcomes in recent years.
  8. Cantwell C, Kenny P, Eustace S. Low radiation dose CT technique for guidance of radiofrequency ablation of osteoid osteoma. Clin Radiol. 2008;63:449-52 pubmed publisher
  9. Murphy K, Baez J, Cooney B, Kabaish K. CT fluoroscopy-guided postmyelographic transthecal radiofrequency ablation of a posterior vertebral body osteoid osteoma. J Vasc Interv Radiol. 2008;19:291-3 pubmed publisher
    The present case report describes a unique case of radiofrequency (RF) ablation of an osteoid osteoma in the inferoposterior paramedian region of the L5 vertebral body...

More Information


  1. Barsa P, Suchomel P, Lukas R, Taller S, Endrych L. [Percutaneous CT-guided radiofrequency ablation in spinal osteoid osteoma treatment]. Acta Chir Orthop Traumatol Cech. 2007;74:401-5 pubmed
    ..Its effectiveness and safety have been reported in a number of studies concerned with the therapy of osteoid osteoma of extremities...
  2. Georgoulis A, Papageorgiou C, Moebius U, Rossis J, Papadonikolakis A, Soucacos P. The diagnostic dilemma created by osteoid osteoma that presents as knee pain. Arthroscopy. 2002;18:32-7 pubmed
    b>Osteoid osteoma is a rare benign bone lesion with a high incidence in adolescents and young people...
  3. Sans N, Galy Fourcade D, Assoun J, Jarlaud T, Chiavassa H, Bonnevialle P, et al. Osteoid osteoma: CT-guided percutaneous resection and follow-up in 38 patients. Radiology. 1999;212:687-92 pubmed
    ..To reevaluate at medium term the results of computed tomography (CT)-guided percutaneous resection of osteoid osteomas...
  4. Schindler A, Hodler J, Michel B, Bruehlmann P. Osteoid osteoma of the capitate. Arthritis Rheum. 2002;46:2808-10 pubmed
  5. Soong M, Jupiter J, Rosenthal D. Radiofrequency ablation of osteoid osteoma in the upper extremity. J Hand Surg Am. 2006;31:279-83 pubmed
    To examine the results of radiofrequency ablation (RFA) of osteoid osteoma in the upper extremity.
  6. Altinel L, Degirmenci B, Kose K, Sahin O. Percutaneous resection of a patellar osteoid osteoma using a cannulated skin punch biopsy needle. Arch Orthop Trauma Surg. 2007;127:299-302 pubmed
    Patella is a very rare localization for osteoid osteoma. Non-specific knee complaints and difficulty to distinguish nidus in direct radiographs may cause a delay in diagnosis and make the definite diagnosis troublesome...
  7. Koós Z, Than P. Rare localization of osteoid osteoma in the patella. Pediatr Radiol. 2005;35:929-30 pubmed
  8. Nourissat G, Kakuda C, Dumontier C. Arthroscopic excision of osteoid osteoma of the elbow. Arthroscopy. 2007;23:799.e1-4 pubmed
    ..Elbow contracture does not have to be treated because it is directly related to the osteoma, and excision of the osteoma will restore full mobility...
  9. Hoffmann R, Jakobs T, Kubisch C, Trumm C, Weber C, Duerr H, et al. Radiofrequency ablation in the treatment of osteoid osteoma-5-year experience. Eur J Radiol. 2010;73:374-9 pubmed publisher
    This study aimed to determine the success and complication rates of radiofrequency ablation (RFA) in treatment of osteoid osteoma (OO) and duration of pain relief. Furthermore value of bone biopsy prior to the RFA was evaluated.
  10. Sierre S, Innocenti S, Lipsich J, Lanfranchi L, Questa H, Moguillansky S. Percutaneous treatment of osteoid osteoma by CT-guided drilling resection in pediatric patients. Pediatr Radiol. 2006;36:115-8 pubmed
    b>Osteoid osteoma is a painful, benign, small osteogenic bone tumor. For a long time, surgery was the only treatment for these lesions. Different minimally invasive therapeutic techniques have been proposed...
  11. Theumann N, Hauser P, Schmidt S, Schnyder P, Leyvraz P, Mouhsine E. [Osteoid osteoma and radiofrequency]. Rev Med Suisse. 2005;1:2989-94 pubmed
    b>Osteoid osteoma and radiofrequency Osteoid osteoma relates to a benign skeletal neoplasm, smaller than 2 cm in diameter, composed of osteoid, highly vascularized connective tissue and surrounded by a ring of bone sclerosis...
  12. Hadjipavlou A, Lander P, Marchesi D, Katonis P, Gaitanis I. Minimally invasive surgery for ablation of osteoid osteoma of the spine. Spine (Phila Pa 1976). 2003;28:E472-7 pubmed
    Compare the effectiveness of two different techniques for the management of osteoid osteoma of the spine.
  13. Garg V, Kapoor S. Osteoid osteoma of scaphoid. J South Orthop Assoc. 2003;12:141-2 pubmed
    b>Osteoid osteoma is infrequently localized to the hand. Initially the lesion may cause nonspecific symptoms. A 14-year-old boy presented with spontaneous onset swelling and pain wrist for 2 months...
  14. Woertler K, Vestring T, Boettner F, Winkelmann W, Heindel W, Lindner N. Osteoid osteoma: CT-guided percutaneous radiofrequency ablation and follow-up in 47 patients. J Vasc Interv Radiol. 2001;12:717-22 pubmed
    To evaluate computed tomography (CT)-guided radiofrequency (RF) ablation as a minimally invasive therapy for osteoid osteoma with regard to technical and clinical success and immediate and delayed complications.
  15. Szendroi M, Köllö K, Antal I, Lakatos J, Szoke G. Intraarticular osteoid osteoma: clinical features, imaging results, and comparison with extraarticular localization. J Rheumatol. 2004;31:957-64 pubmed
    Intraarticular osteoid osteoma is uncommon and presents diagnostic difficulties, which are important for both rheumatologists and orthopedic surgeons...
  16. Papathanassiou Z, Megas P, Petsas T, Papachristou D, Nilas J, Siablis D. Osteoid osteoma: diagnosis and treatment. Orthopedics. 2008;31:1118 pubmed
  17. Arazi M, Memik R, Yel M, Ogun T. Osteoid osteoma of the carpal bones. Arch Orthop Trauma Surg. 2001;121:119-20 pubmed
    b>Osteoid osteoma is a benign bone tumor that rarely localizes in the hand or the carpal bones. We report two cases of osteoid osteoma localized in two different carpal bones. Unremitting wrist pain was a major clinical symptom...
  18. Ghanem I, Collet L, Kharrat K, Samaha E, Deramon H, Mertl P, et al. Percutaneous radiofrequency coagulation of osteoid osteoma in children and adolescents. J Pediatr Orthop B. 2003;12:244-52 pubmed
    The purpose of this paper was to evaluate the effectiveness of percutaneous radiofrequency ablation of osteoid osteoma in children and adolescents. Twenty-three patients aged 4.5-19.5 years were retrospectively reviewed...
  19. Alvarez M, Moneo P, Palacios J. Arthroscopic extirpation of an osteoid osteoma of the acetabulum. Arthroscopy. 2001;17:768-71 pubmed
    ..resonance imaging, bone scan, and computed tomography were necessary to finally diagnose an acetabulum osteoid osteoma (AOO). Excision of the lesion was performed arthroscopically and pathologic testing confirmed the diagnosis...
  20. Jones A, Prihoda T, Kacher J, Odingo N, Freedman P. Osteoblastoma of the maxilla and mandible: a report of 24 cases, review of the literature, and discussion of its relationship to osteoid osteoma of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;102:639-50 pubmed
    ..and radiographic characteristics of this neoplasm to 53 previously reported examples of osteoblastoma and osteoid osteoma in the jaws...
  21. Franceschi F, Marinozzi A, Papalia R, Longo U, Gualdi G, Denaro E. Intra- and juxta-articular osteoid osteoma: a diagnostic challenge : misdiagnosis and successful treatment: a report of four cases. Arch Orthop Trauma Surg. 2006;126:660-7 pubmed
    b>Osteoid osteoma is a benign tumour in young adults. The clinical manifestations are generally typical nocturnal pain that prevents sleep and that is alleviated with aspirin...
  22. Manjunatha B, Nagarajappa D. Osteoid osteoma. Indian J Dent Res. 2009;20:514-5 pubmed publisher
    b>Osteoid osteoma is a benign tumor of the bone which arises from osteoblasts and is extremely rare in jaws. Only 15 cases of osteoid osteoma have been reported in English-language literature...
  23. Van Royen B, Baayen J, Pijpers R, Noske D, Schakenraad D, Wuisman P. Osteoid osteoma of the spine: a novel technique using combined computer-assisted and gamma probe-guided high-speed intralesional drill excision. Spine (Phila Pa 1976). 2005;30:369-73 pubmed
    A report of five cases of thoracolumbar osteoid osteoma treated with combined computer-assisted and gamma probe-guided high-speed drill excision.
  24. von Chamier G, Holl Wieden A, Stenzel M, Raab P, Darge K, Girschick H, et al. Pitfalls in diagnostics of hip pain: osteoid osteoma and osteoblastoma. Rheumatol Int. 2010;30:395-400 pubmed publisher
    b>Osteoid osteoma and osteoblastoma are benign bone tumors that occur most often in adolescents and predominantly in males...
  25. Vanderschueren G, Taminiau A, Obermann W, Bloem J. Osteoid osteoma: clinical results with thermocoagulation. Radiology. 2002;224:82-6 pubmed
    To determine the clinical results in an unselected group of consecutive patients with osteoid osteoma treated with thermocoagulation.
  26. Torriani M, Rosenthal D. Percutaneous radiofrequency treatment of osteoid osteoma. Pediatr Radiol. 2002;32:615-8 pubmed
    b>Osteoid osteoma is a small osteogenic tumor usually found in the lower extremity of children and young adults...
  27. Davies M, Cassar Pullicino V, Davies A, McCall I, Tyrrell P. The diagnostic accuracy of MR imaging in osteoid osteoma. Skeletal Radiol. 2002;31:559-69 pubmed
    ..To analyse the MR imaging appearances of a large series of osteoid osteomas, to assess the ability of MR imaging to detect the tumour, and to identify potential reasons for misdiagnosis...
  28. Rizzello G, Longo U, Maffulli N, Denaro V. Arthroscopic removal of an intraarticular osteoid osteoma of the distal tibia. J Foot Ankle Surg. 2010;49:398.e17-21 pubmed publisher
    ..aspects of arthroscopic excision, and results of surgery in a 28-year-old woman who had an intraarticular osteoid osteoma of her left ankle, in whom the initial diagnosis was erroneous and delayed 1 year...
  29. Laffosse J, Tricoire J, Cantagrel A, Wagner A, Puget J. Osteoid osteoma of the carpal bones. Two case reports. Joint Bone Spine. 2006;73:560-3 pubmed
    b>Osteoid osteoma rarely develops in the wrist. The symptoms resemble atypical tenosynovitis, with variations according to the location of the tumor. As a result, diagnostic wanderings are common...
  30. Finstein J, Hosalkar H, Ogilvie C, Lackman R. Case reports: an unusual complication of radiofrequency ablation treatment of osteoid osteoma. Clin Orthop Relat Res. 2006;448:248-51 pubmed
    b>Osteoid osteoma is a benign bone tumor traditionally treated nonoperatively or by operative excision. However, radiofrequency ablation is being used increasingly for treatment, as there are several reports supporting its effectiveness...
  31. Albisinni U, Rimondi E, Malaguti M, Ciminari R. A comment on CT-guided radiofrequency thermal ablation of osteoid osteoma. AJR Am J Roentgenol. 2004;183:538; author reply 538-9 pubmed
  32. Cichon C, Bottner F, Rodl R, Winkelmann W, Lindner N. [Minimally invasive treatment of osteoid osteoma with CT-guided radiofrequency ablation in long-term follow-up]. Z Orthop Ihre Grenzgeb. 2006;144:332-7 pubmed
    We treated 74 patients with symptomatic osteoid osteoma by CT-guided radiofrequency ablation (CT-RF) and investigated the rate of success and complications.
  33. Pfeiffer M, Sluga M, Windhager R, Dominkus M, Kotz R. [Surgical treatment of osteoid osteoma of the extremities]. Z Orthop Ihre Grenzgeb. 2003;141:345-8 pubmed
  34. Kettunen J, Makela E, Kauppinen T. Gamma probe localization in the surgical treatment of osteoid osteoma. Scand J Surg. 2003;92:224-6 pubmed
    b>Osteoid osteoma is a benign bone tumor typically inducing night pain. It has traditionally been treated with operative excision...
  35. Gangi A, Alizadeh H, Wong L, Buy X, Dietemann J, Roy C. Osteoid osteoma: percutaneous laser ablation and follow-up in 114 patients. Radiology. 2007;242:293-301 pubmed
    To retrospectively evaluate the effectiveness of interstitial laser ablation (ILA) as a curative treatment of osteoid osteoma.
  36. Uda H, Mizuzeki T, Tsuge K. Osteoid osteoma of the metacarpal bone presenting after an injury. Scand J Plast Reconstr Surg Hand Surg. 2002;36:238-42 pubmed
    We present a case of osteoid osteoma of the right third metacarpal bone in a 23-year-old man. He had an apparent history of initial injury, followed by pain and swelling...
  37. Rosenthal D, Hornicek F, Torriani M, Gebhardt M, Mankin H. Osteoid osteoma: percutaneous treatment with radiofrequency energy. Radiology. 2003;229:171-5 pubmed
    To report our experience with technical success, complications, and long-term clinical success of radiofrequency (RF) ablation of osteoid osteoma.
  38. Gebauer B, Tunn P, Gaffke G, Melcher I, Felix R, Stroszczynski C. Osteoid osteoma: experience with laser- and radiofrequency-induced ablation. Cardiovasc Intervent Radiol. 2006;29:210-5 pubmed
    The purpose of this study was to analyze the clinical outcome of osteoid osteoma treated by thermal ablation after drill opening. A total of 17 patients and 20 procedures were included...
  39. Cove J, Taminiau A, Obermann W, Vanderschueren G. Osteoid osteoma of the spine treated with percutaneous computed tomography-guided thermocoagulation. Spine (Phila Pa 1976). 2000;25:1283-6 pubmed
    Two cases are reported in which an osteoid osteoma of the lumbar spine was treated with CT-guided thermocoagulation.
  40. Themistocleous G, Chloros G, Mavrogenis A, Khaldi L, Papagelopoulos P, Efstathopoulos D. Unusual presentation of osteoid osteoma of the scaphoid. Arch Orthop Trauma Surg. 2005;125:482-5 pubmed
    ..The authors present herein an unusual case of osteoid osteoma of the scaphoid superimposed on a wrist injury caused by a fall on the outstretched hand.
  41. Rosenthal D, Hornicek F, Wolfe M, Jennings L, Gebhardt M, Mankin H. Percutaneous radiofrequency coagulation of osteoid osteoma compared with operative treatment. J Bone Joint Surg Am. 1998;80:815-21 pubmed
    b>Osteoid osteoma, a benign bone tumor, has traditionally been treated with operative excision. A recently developed method for percutaneous ablation of the tumor has been proposed as an alternative to operative treatment...
  42. Gaeta M, Minutoli F, Pandolfo I, Vinci S, D Andrea L, Blandino A. Magnetic resonance imaging findings of osteoid osteoma of the proximal femur. Eur Radiol. 2004;14:1582-9 pubmed
    b>Osteoid osteoma (OO) is a benign bone tumor whose main radiological finding is nidus. OO of the proximal femur can also result in non-specific findings such as hip joint effusion, perinidal bone marrow edema and soft tissue mass...
  43. Franceschi F, Longo U, Ruzzini L, Marinozzi A, Rizzello G, Papalia R, et al. En-bloc retrograde resection of an osteoid osteoma of the patella using computed tomography under arthroscopic control. J Knee Surg. 2008;21:136-40 pubmed
    Periarticular osteoid osteoma of the knee is a diagnostic and therapeutic challenge...
  44. Lee M, Ahn J, Chung H, Lim H, Suh J, Kwag H, et al. Osteoid osteoma treated with percutaneous radiofrequency ablation: MR imaging follow-up. Eur J Radiol. 2007;64:309-14 pubmed
    We evaluated follow-up magnetic resonance (MR) images for osteoid osteoma treated with percutaneous radiofrequency ablation (RFA).
  45. Liu P, Chivers F, Roberts C, Schultz C, Beauchamp C. Imaging of osteoid osteoma with dynamic gadolinium-enhanced MR imaging. Radiology. 2003;227:691-700 pubmed
    ..To compare dynamic gadolinium-enhanced T1-weighted magnetic resonance (MR) imaging with nonenhanced T1-weighted and T2-weighted MR imaging and thin-section computed tomography (CT) for the demonstration of osteoid osteomas...
  46. Jayakumar P, Harish S, Nnadi C, Noordeen H, Saifuddin A. Symptomatic resolution of spinal osteoid osteoma with conservative management: imaging correlation. Skeletal Radiol. 2007;36 Suppl 1:S72-6 pubmed
    ..and magnetic resonance imaging (MRI), demonstrated a lesion with radiological features consistent with an osteoid osteoma (OO) of the 6th thoracic vertebra...
  47. Lee E, Shafi M, Hui J. Osteoid osteoma: a current review. J Pediatr Orthop. 2006;26:695-700 pubmed
  48. Ramnath R, Rosenthal D, Cates J, Gebhardt M, Quinn R. Intracortical chondroma simulating osteoid osteoma treated by radiofrequency. Skeletal Radiol. 2002;31:597-602 pubmed
    ..Pathologic evaluation of the specimens revealed features consistent with benign intracortical chondroma. In one case radiofrequency treatment appears to have cured the tumor. The other patient required operative intervention...
  49. Weits T, van der Werf G. Subperiosteal osteoid osteoma of the right acetabulum. JBR-BTR. 2006;89:162-3 pubmed
  50. Kawahara C, Tanaka Y, Kato H, Watanabe S, Kokubun S. Myolysis of the erector spinae muscles as the cause of scoliosis in osteoid osteoma of the spine. Spine (Phila Pa 1976). 2002;27:E313-5 pubmed
    A case of an osteoid osteoma at the lower thoracic spine with scoliosis is reported.
  51. Bertoletti F, Capolunghi B, Bertolini G, Cascio F, Bracci A. Giant osteoid osteoma of ethmoid sinus: role of functional endoscopic sinus surgery. Acta Otorhinolaryngol Ital. 2004;24:297-301 pubmed
  52. Nagashima H, Nishi T, Yamane K, Tanida A. Case report: osteoid osteoma of the C2 pedicle: surgical technique using a navigation system. Clin Orthop Relat Res. 2010;468:283-8 pubmed publisher
    An osteoid osteoma of the cervical spinal pedicle is rare and carries a high surgical risk because of the close anatomic relationship to the spinal cord, nerve root, and vertebral artery...
  53. Peyser A, Applbaum Y, Simanovsky N, Safran O, Lamdan R. CT-guided radiofrequency ablation of pediatric osteoid osteoma utilizing a water-cooled tip. Ann Surg Oncol. 2009;16:2856-61 pubmed publisher
    Radiofrequency ablation (RFA) has a success rate of 70% to 90% in the treatment of osteoid osteoma (OO)...