Summary: A benign tumor composed of bone tissue or a hard tumor of bonelike structure developing on a bone (homoplastic osteoma) or on other structures (heteroplastic osteoma). (From Dorland, 27th ed)

Top Publications

  1. Fobe L, Melo E, Cannone L, Fobe J. [Surgery of frontal sinus osteoma]. Arq Neuropsiquiatr. 2002;60:101-5 pubmed
    ..Five patients having the diagnosis of frontal sinus osteoma were operated on between 1995 and 1999. Medium age was 38.4 years (from 12 to 55 years), 3 male and 2 female...
  2. Shields C, Sun H, Demirci H, Shields J. Factors predictive of tumor growth, tumor decalcification, choroidal neovascularization, and visual outcome in 74 eyes with choroidal osteoma. Arch Ophthalmol. 2005;123:1658-66 pubmed
    To evaluate choroidal osteoma for tumor growth, tumor decalcification, related choroidal neovascularization, visual acuity loss, and poor visual acuity.
  3. Miman M, Bayindir T, Akarcay M, Erdem T, Selimoglu E. Endoscopic removal technique of a huge ethmoido-orbital osteoma. J Craniofac Surg. 2009;20:1403-6 pubmed publisher
    ..Osteomas become symptomatic when they extend to the orbit or cranium. We report a rare case of ethmoido-orbital osteoma. Case reports and a review of the literature concerning osteoma and surgical techniques are presented...
  4. Morris R, Prabhu V, Shah P, Narendran V. Combination therapy of low-fluence photodynamic therapy and intravitreal ranibizumab for choroidal neovascular membrane in choroidal osteoma. Indian J Ophthalmol. 2011;59:394-6 pubmed publisher
    Choroidal osteoma is an unusual form of intraocular calcification seen in otherwise healthy eyes. It is a benign idiopathic osseous tumor of the choroid, typically seen in young females...
  5. Arvin B, Panchmatia J, Casey A. Cervical C2 osteoma, unusual presentation and transoral approach for complete excision. Spine J. 2009;9:e9-11 pubmed publisher
    ..The authors discuss a case of a 70-year-old lady with an unusual presentation of a cervical C2 osteoma. The presentation was with mild dysphagia and pressure symptoms behind the left ear similar to earache ..
  6. Hayden M, Guzman R, Dulai M, Mobley B, Edwards M. Recurring osteoma within a calcium phosphate bone cement cranioplasty: case report. Neurosurgery. 2009;64:E775-6; discussion E776 pubmed publisher
    We present a unique case of a recurrent osteoma within a cranioplasty performed with calcium phosphate bone cement.
  7. Hanley C, Gieger T, Frank P. What is your diagnosis? Multilobular osteoma (MLO). J Am Vet Med Assoc. 2004;225:1665-6 pubmed
  8. Hsiao S, Liu T. Osteoma of the external ear canal. Otol Neurotol. 2003;24:960 pubmed
  9. de Chalain T, Tan B. Ivory osteoma of the craniofacial skeleton. J Craniofac Surg. 2003;14:729-35 pubmed
    ..The authors describe the clinical presentation, investigation, and surgical management of two cases of benign ivory osteoma of the craniofacial skeleton...

More Information


  1. Kaplan I, Nicolaou Z, Hatuel D, Calderon S. Solitary central osteoma of the jaws: a diagnostic dilemma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106:e22-9 pubmed publisher
    ..A search of the literature identified 91 well documented cases of solitary osteoma of the jaws published since 1955: 93.4% were peripheral and only 6...
  2. Narayanan R, Shah V. Intravitreal bevacizumab in the management of choroidal neovascular membrane secondary to choroidal osteoma. Eur J Ophthalmol. 2008;18:466-8 pubmed
    To describe a patient with choroidal neovascular membrane (CNVM) secondary to choroidal osteoma treated successfully with intravitreal bevacizumab.
  3. Ebrahim F, Jacobson J, Lin J, Housner J, Hayes C, Resnick D. Intraarticular osteoid osteoma: sonographic findings in three patients with radiographic, CT, and MR imaging correlation. AJR Am J Roentgenol. 2001;177:1391-5 pubmed
    Intraarticular osteoid osteoma often has subtle radiographic findings and nonspecific clinical features; further diagnostic workup of unexplained joint pain may involve musculoskeletal sonography...
  4. Song J, Bae J, Rho M, Lee S. Intravitreal bevacizumab in the management of subretinal fluid associated with choroidal osteoma. Retina. 2010;30:945-51 pubmed publisher
    The purpose of this study was to evaluate the effect of intravitreal injection of bevacizumab on subretinal fluid associated with choroidal osteoma.
  5. Cheon J, Kim J, Yang H. CT and pathologic findings of a case of subdural osteoma. Korean J Radiol. 2002;3:211-3 pubmed
    ..The hard bony mass found and excised during surgery was shown at histopathologic examination to be a subdural osteoma. We describe the clinicopathologic findings of this entity and discuss the radiological features which suggest ..
  6. Cho Y, Kim J, Hong S, Chung W. A huge osteoma of the middle ear. Int J Pediatr Otorhinolaryngol. 2005;69:1569-74 pubmed
    ..We report a case of a huge middle ear osteoma along with compatible radiological findings filling the whole tympanum and the Eustachian tube, which caused ..
  7. Kovacic J, Subaric M, Lajtman Z, Curcic I. Osteoma of the internal auditory canal. Acta Med Croatica. 2001;55:215-8 pubmed
    ..A patient with an osteoma of the internal auditory canal is presented, along with differential diagnosis and possible etiologic factors for ..
  8. Sharma S, Sribhargava N, Shanmugam M. Choroidal neovascular membrane associated with choroidal osteoma (CO) treated with trans-pupillary thermo therapy. Indian J Ophthalmol. 2004;52:329-30 pubmed
    Choroidal neovascular membrane, a known complication of choroidal osteoma causing visual loss when located subfoveally, can be successfully treated with transpupillary thermo therapy.
  9. Panagiotopoulos V, Tzortzidis F, Partheni M, Iliadis H, Fratzoglou M. Giant osteoma of the frontoethmoidal sinus associated with two cerebral abscesses. Br J Oral Maxillofac Surg. 2005;43:523-5 pubmed
    ..Radiographic studies showed a giant frontoethmoidal osteoma, that extended intracranially into the frontal lobe and was associated with two abscesses, one within the lesion ..
  10. de Santana Santos T, Frota R, Martins Filho P, Melo A, de Souza Andrade E, de Oliveira e Silva E, et al. Central osteoma of the maxilla with involvement of paranasal sinus. J Craniofac Surg. 2011;22:589-91 pubmed publisher
    b>Osteoma is an osteoblastic benign tumor characterized by the proliferation of either compact or cancellous bone...
  11. Sisk R, Riemann C, Petersen M, Foster R, Miller D, Murray T, et al. Fundus autofluorescence findings of choroidal osteoma. Retina. 2013;33:97-104 pubmed publisher
    ..To describe fundus autofluorescence (FAF) characteristics associated with choroidal osteomas and their secondary complications...
  12. Huang H, Liu C, Lin K, Chen H. Giant ethmoid osteoma with orbital extension, a nasoendoscopic approach using an intranasal drill. Laryngoscope. 2001;111:430-2 pubmed
    Ethmoid osteoma is a slow-growing, benign, and encapsulated bony tumor. Symptoms occur earlier than with osteomas of the frontal sinus because of the small volume of the ethmoid sinus. Interestingly, orbital extension is uncommon...
  13. Boedts M, Hermans R, Feenstra L. Osteoma of the internal auditory canal. Acta Otorhinolaryngol Belg. 1997;51:191-3 pubmed
    A case of an osteoma of the internal auditory canal in a patient with severe hearing loss is presented. Osteomata of the internal auditory canal have only rarely been diagnosed...
  14. Akiyama M, Tanaka T, Hasegawa Y, Chiba S, Abe T. Multiple intracranial subarachnoid osteomas. Acta Neurochir (Wien). 2005;147:1085-9; discussion 1089 pubmed
    ..Intracranial osteomas, which have no connections with the dura or the skull, are very rare. Here we report one case of multiple intracranial subarachnoid osteomas...
  15. Bilkay U, Erdem O, Ozek C, Helvaci E, Kilic K, Ertan Y, et al. Benign osteoma with Gardner syndrome: review of the literature and report of a case. J Craniofac Surg. 2004;15:506-9 pubmed
    ..b>Osteoma is a benign neoplasm of bone tissue that is characterized by slow continuous growth and is the most common ..
  16. Woldenberg Y, Nash M, Bodner L. Peripheral osteoma of the maxillofacial region. Diagnosis and management: a study of 14 cases. Med Oral Patol Oral Cir Bucal. 2005;10 Suppl 2:E139-42 pubmed
    The purpose of the article was to present 14 new cases of peripheral osteoma and to evaluate the diagnosis and management of peripheral osteoma of the maxillofacial region with an analysis of the literature.
  17. Kerckhaert A, Wolvius E, van der Wal K, Oosterhuis J. A giant osteoma of the mandible: case report. J Craniomaxillofac Surg. 2005;33:282-5 pubmed
    A 53-year-old patient with a giant osteoma of the right mandible is presented. The clinicopathological features of osteoma of the mandible are discussed and Gardner's syndrome was excluded.
  18. Ogbureke K, Nashed M, Ayoub A. Huge peripheral osteoma of the mandible: a case report and review of the literature. Pathol Res Pract. 2007;203:185-8 pubmed
    ..Here, we report a case of a huge solitary peripheral osteoma of the lingual posterior mandible in a 50-year-old woman who was otherwise in good health...
  19. Becelli R, Santamaria S, Saltarel A, Carboni A, Iannetti G. Endo-orbital osteoma: two case reports. J Craniofac Surg. 2002;13:493-6 pubmed
    b>Osteoma is a benign, slow-growing tumor, which mainly occurs in the bones and cavities of the middle third of the face, representing the most frequent benign tumor of the paranasal sinuses...
  20. Jung T, Jung S, Jin S, Jin Y, Kim I, Kang S. Solitary intracranial subdural osteoma: intraoperative findings and primary anastomosis of an involved cortical vein. J Clin Neurosci. 2007;14:468-70 pubmed
    We report a patient with a intracranial subdural osteoma with a large cortical vein passing through the subdural calcified mass. A 60-year-old man presented with an approximately 3-year history of persistent headache...
  21. Larnaout A, Amouri R, Neji S, Zouari M, Kaabachi N, Hentati F. Osteoma of the calvaria in L-2-hydroxyglutaric aciduria. J Inherit Metab Dis. 2007;30:980 pubmed
    ..At the age of 20 years, an osteoma of the right frontal bone was diagnosed...
  22. Lin C, Lin Y, Kang B. Middle turbinate osteoma presenting with ipsilateral facial pain, epiphora, and nasal obstruction. Otolaryngol Head Neck Surg. 2003;128:282-3 pubmed
  23. Sibony P, Shindo M. Orbital osteoma with gaze-evoked amaurosis. Arch Ophthalmol. 2004;122:788 pubmed
  24. Naraghi M, Kashfi A. Endonasal endoscopic resection of ethmoido-orbital osteoma compressing the optic nerve. Am J Otolaryngol. 2003;24:408-12 pubmed
    ..We report resection of a large ethmoido-orbital osteoma via endonasal endoscopic approach with minimal morbidity...
  25. Park W, Kim H. Osteoma of maxillary sinus: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;102:e26-7 pubmed
    ..01% to 0.43% of patients; of these, up to 80% occur in the frontal sinus. An osteoma of maxillary sinus is extremely rare...
  26. Browning D. Choroidal osteoma: observations from a community setting. Ophthalmology. 2003;110:1327-34 pubmed
    To determine the characteristics of choroidal osteoma arising from a previously unreported patient population and to document new observations in this condition.
  27. D Errico G, Rosa M, Soluri A, Scafè R, Galli M, Chiarini S, et al. Radioguided biopsy of osteoid osteoma: usefulness of imaging probe. Tumori. 2002;88:S30-2 pubmed
    When removal of osteoid osteoma is performed with open biopsy, the surgeon can be guided by radioactivity of 99mTc-MDP (methylene D- phosphonate) acquired by a probe.
  28. Johann A, de Freitas J, de Aguiar M, de Araujo N, Mesquita R. Peripheral osteoma of the mandible: case report and review of the literature. J Craniomaxillofac Surg. 2005;33:276-81 pubmed
    b>Osteoma is a benign often asymptomatic neoplasm, consisting of well-differentiated mature bone...
  29. Dalambiras S, Boutsioukis C, Tilaveridis I. Peripheral osteoma of the maxilla: report of an unusual case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100:e19-24 pubmed
    Peripheral osteomas of the maxilla are relatively rare. A case of a solitary peripheral osteoma of the anterior right maxilla in a 16-year-old girl is presented...
  30. Zouloumis L, Lazaridis N, Maria P, Epivatianos A. Osteoma of the ethmoidal sinus: a rare case of recurrence. Br J Oral Maxillofac Surg. 2005;43:520-2 pubmed
    ..We describe an unusual case of an osteoma in the ethmoid sinus that recurred 5 years after its resection at another hospital...
  31. Jurlina M, Janjanin S, Melada A, Prstacić R, Veselić A. Large intracranial intradural mucocele as a complication of frontal sinus osteoma. J Craniofac Surg. 2010;21:1126-9 pubmed publisher
    ..We report on an unusual case of frontal sinus osteoma in a 27-year-old patient, complicated by large secondary mucocele that eroded the bone and extended into the ..
  32. Iatrou I, Leventis M, Dais P, Tosios K. Peripheral osteoma of the maxillary alveolar process. J Craniofac Surg. 2007;18:1169-73 pubmed
    b>Osteoma is a benign, slow-growing tumor characterized by proliferation of compact or cancellous bone. Solitary osteomas are classified as peripheral, central, or extraskeletal...
  33. Aghabeigi B, Evans A, Crean S, Hopper C. Simultaneous repair of an orbital floor fracture and removal of an ethmoid osteoma: case report and review of the literature. Int J Oral Maxillofac Surg. 2003;32:94-6 pubmed
    A case is presented of an ethmoid osteoma, which was discovered during the investigation of an orbital floor fracture...
  34. Adegbite N, Xu M, Kaplan F, Shore E, Pignolo R. Diagnostic and mutational spectrum of progressive osseous heteroplasia (POH) and other forms of GNAS-based heterotopic ossification. Am J Med Genet A. 2008;146A:1788-96 pubmed publisher
    ..g., POH) from the non-progressive forms (osteoma cutis, AHO, and PHP1a/c).
  35. Sayan N, Ucok C, Karasu H, Gunhan O. Peripheral osteoma of the oral and maxillofacial region: a study of 35 new cases. J Oral Maxillofac Surg. 2002;60:1299-301 pubmed
    The purpose of this article was to present 35 new cases of peripheral osteoma of the oral and maxillofacial region with an analysis of the literature.
  36. Ishimaru T. Superior turbinate osteoma: a case report. Auris Nasus Larynx. 2005;32:291-3 pubmed
    Turbinate osteoma is very rare and only three middle turbinate cases have been previously reported in the literature. A case of superior turbinate osteoma has never been reported before...
  37. Savastano M, Guarda Nardini L, Marioni G, Staffieri A. The bicoronal approach for the treatment of a large frontal sinus osteoma. A technical note. Am J Otolaryngol. 2007;28:427-9 pubmed
  38. Durighetto A, de Moraes Ramos F, da Rocha M, da Cruz Perez D. Peripheral osteoma of the maxilla: report of a case. Dentomaxillofac Radiol. 2007;36:308-10 pubmed
    ..In the jaw, these are uncommon lesions. Excluding the maxillary sinus, there are only eight cases of maxillary osteoma reported in the English-language literature...
  39. Izci Y. Management of the large cranial osteoma: experience with 13 adult patients. Acta Neurochir (Wien). 2005;147:1151-5; discussion 1155 pubmed
    ..Large osteomas are benign, slow-growing and rare neoplasms of the skull, which are usually asymptomatic but may need surgical resection...
  40. Tarsitano A, Marchetti C. Unusual presentation of obstructive sleep apnoea syndrome due to a giant mandible osteoma: case report and literature review. Acta Otorhinolaryngol Ital. 2013;33:63-6 pubmed
    ..Herein, we report an unusual case of giant osteoma of the mandible depressing the lateral pharyngeal wall, interfering with normal respiration during the night...
  41. Jang C, Cho Y. Osteoma of the incus with congenital cholesteatoma: a case report. Auris Nasus Larynx. 2009;36:349-52 pubmed publisher
    ..Among them, only one case osteoma with congenital cholesteatoma has been reported...
  42. Viswanatha B. Maxillary sinus osteoma: two cases and review of the literature. Acta Otorhinolaryngol Ital. 2012;32:202-5 pubmed
    ..Symptoms arise when osteomas obstruct the ostium of the sinus or impinge on adjacent orbital or intracranial structures. Two cases of maxillary sinus osteoma are presented along with a review of the literature.
  43. Kutluhan A, Salviz M, Bozdemir K, Değer H, Culha I, Ozveren M. Middle turbinate osteoma extending into anterior cranial fossa. Auris Nasus Larynx. 2009;36:702-4 pubmed publisher
    Middle turbinate osteoma is very rare and only two times have been reported before. We reported a 31-year old male presenting middle turbinate osteoma that extending into the anterior cranial fossa, causing pneumocephalus...
  44. Chen J, Lee L, Gass J. Choroidal osteoma: evidence of progression and decalcification over 20 years. Clin Exp Optom. 2006;89:90-4 pubmed
    Choroidal osteoma is a rare, benign, ossifying tumour of the choroid of unknown aetiology...
  45. Ertas U, Tozoglu S. Uncommon peripheral osteoma of the mandible: report of two cases. J Contemp Dent Pract. 2003;4:98-104 pubmed
    The osteoma is a benign osteogenic neoplasm of bone. Peripheral osteoma of the mandible is uncommon. It is often asymptomatic and usually discovered when a patient complains of esthetic problems and presents for treatment...
  46. Shimizu T, Okamoto K, Majima Y. Osteoma of the malleus: a case report and literature review. Am J Otolaryngol. 2003;24:239-41 pubmed
  47. Gerbrandy S, Saeed P, Fokkens W. Endoscopic and trans-fornix removal of a giant orbital-ethmoidal osteoma. Orbit. 2007;26:299-301 pubmed
    ..The osteoma was successfully removed using an inferior and medial orbitotomy with swinging eyelid combined with an endoscopic ..
  48. Pagella F, Giourgos G, Matti E, Colombo A, Carena P. Removal of a fronto-ethmoidal osteoma using the sonopet omni ultrasonic bone curette: first impressions. Laryngoscope. 2008;118:307-9 pubmed
    ..In this case report, we present the first clinical ENT experience with this device in removing a fronto-ethmoidal osteoma, and we briefly discuss our impressions.
  49. Melroy C, Senior B. Benign sinonasal neoplasms: a focus on inverting papilloma. Otolaryngol Clin North Am. 2006;39:601-17, x pubmed
    ..This article aimed to familiarize the clinician with all the practical aspects of inverting papilloma and its management. The treatment algorithm for this tumor has undergone a complex evolution that continues today...
  50. Mesolella M, Galli V, Testa D. Inferior turbinate osteoma: a rare cause of nasal obstruction. Otolaryngol Head Neck Surg. 2005;133:989-91 pubmed
  51. Gurelik G, Lonneville Y, Safak N, Ozdek S, Hasanreisoglu B. A case of choroidal osteoma with subsequent laser induced decalcification. Int Ophthalmol. 2001;24:41-3 pubmed
    A rare benign tumor, choroidal osteoma with accompanying choroidal neovascularization treated with laser photocoagulation is reported. Limited decalcification was noted at the borders of laser photocoagulation.
  52. Sugimoto K, Nakahara I, Nishikawa M, Tanaka M, Terashima T, Yanagihara H, et al. [Osteoma originating in the dura: a case report]. No Shinkei Geka. 2001;29:993-6 pubmed
    We report a case of intracranial osteoma attached to the dura. The patient, a 35-year-old man, had suffered several episodes of vertigo over the previous two years. Physical and neurological findings on admission were unremarkable...
  53. Altman J, Nehal K, Busam K, Halpern A. Treatment of primary miliary osteoma cutis with incision, curettage, and primary closure. J Am Acad Dermatol. 2001;44:96-9 pubmed
    Primary miliary osteoma cutis is characterized by de novo bone formation in skin without a known associated or pre-existing cutaneous disorder. These lesions often develop on the face and cause cosmetic concern.