myxoid liposarcoma

Summary

Summary: A liposarcoma containing myxomatous tissue. (Dorland, 27th ed)

Top Publications

  1. Estourgie S, Nielsen G, Ott M. Metastatic patterns of extremity myxoid liposarcoma and their outcome. J Surg Oncol. 2002;80:89-93 pubmed
    ..Extremity myxoid liposarcomas have a unique extrapulmonary metastatic potential. We studied the metastatic pattern of extremity liposarcomas to determine what types of posttreatment imaging may be of value in the follow-up these patients...
  2. Watanabe H, Ohmori K, Kanamori M, Araki N, Yoshikawa H, Kimura T. A myxoid liposarcoma in the lower leg, with a large intra-abdominal metastasis. J Orthop Sci. 2001;6:95-7 pubmed
    We report a patient with a large intra-abdominal metastasis of myxoid liposarcoma. The patient first noticed an asymptomatic mass in her left leg in 1985, when she was 20 years old...
  3. Schwab J, Boland P, Guo T, Brennan M, Singer S, Healey J, et al. Skeletal metastases in myxoid liposarcoma: an unusual pattern of distant spread. Ann Surg Oncol. 2007;14:1507-14 pubmed
    b>Myxoid liposarcoma (MLS), the second most common subtype of liposarcoma, occurs predominantly in the extremities of young adults and has a disproportionately high tendency to metastasize to unusual soft tissue locations, before ..
  4. Hosaka T, Nakashima Y, Kusuzaki K, Murata H, Nakayama T, Nakamata T, et al. A novel type of EWS-CHOP fusion gene in two cases of myxoid liposarcoma. J Mol Diagn. 2002;4:164-71 pubmed
    ..The association of these clinical and histopathological features suggests a distinct biological property for this rare type of fusion product...
  5. Schwab J, Boland P, Antonescu C, Bilsky M, Healey J. Spinal metastases from myxoid liposarcoma warrant screening with magnetic resonance imaging. Cancer. 2007;110:1815-22 pubmed
    b>Myxoid liposarcoma (MLS) has an unusual tendency for extrapulmonary metastasis, particularly to the spine and soft tissues...
  6. Matsui Y, Ueda T, Kubo T, Hasegawa T, Tomita Y, Okamoto M, et al. A novel type of EWS-CHOP fusion gene in myxoid liposarcoma. Biochem Biophys Res Commun. 2006;348:437-40 pubmed
    ..We describe here a case of myxoid liposarcoma containing a novel EWS-CHOP chimeric transcript and identified the breakpoint occurring in intron 13 of EWS...
  7. Favia G, Maiorano E, Orsini G, Piattelli A. Myxoid liposarcoma of the oral cavity with involvement of the periodontal tissues. J Clin Periodontol. 2001;28:109-12 pubmed
    ..The clinical differential diagnosis included peripheral giant cell granuloma, salivary gland neoplasms, squamous cell carcinoma of the gingiva, sarcoma and malignant lymphoma...
  8. Panagis A, Karydas G, Vasilakakis J, Chatzipaschalis E, Lambropoulou M, Papadopoulos N. Myxoid liposarcoma of the spermatic cord: a case report and review of the literature. Int Urol Nephrol. 2003;35:369-72 pubmed
    b>Myxoid liposarcoma of the spermatic cord (MLSC) is a rare variance of spermatic sarcomas, with only 14 previous cases having been reported. Typically it presents during the seventh decade of life as a painless scrotal or inguinal mass...
  9. Pitson G, Robinson P, Wilke D, Kandel R, White L, Griffin A, et al. Radiation response: an additional unique signature of myxoid liposarcoma. Int J Radiat Oncol Biol Phys. 2004;60:522-6 pubmed
    Historically, myxoid liposarcoma (MLS) has been reported to show a marked clinical response to radiotherapy (RT), but objective data to support that contention have been lacking...

More Information

Publications75

  1. Sung M, Kang H, Suh J, Lee J, Park J, Kim J, et al. Myxoid liposarcoma: appearance at MR imaging with histologic correlation. Radiographics. 2000;20:1007-19 pubmed
    Although myxoid liposarcoma is a subtype of liposarcoma, it may be difficult to establish the correct diagnosis with magnetic resonance (MR) imaging due to the lack of fat signal intensity...
  2. Ishii T, Ueda T, Myoui A, Tamai N, Hosono N, Yoshikawa H. Unusual skeletal metastases from myxoid liposarcoma only detectable by MR imaging. Eur Radiol. 2003;13 Suppl 4:L185-91 pubmed
    We present two cases of skeletal metastases from myxoid liposarcoma, occurring several years after treatment of the primary tumors in the lower limb...
  3. Göransson M, Elias E, Ståhlberg A, Olofsson A, Andersson C, Aman P. Myxoid liposarcoma FUS-DDIT3 fusion oncogene induces C/EBP beta-mediated interleukin 6 expression. Int J Cancer. 2005;115:556-60 pubmed
    ..beta controlled gene IL6 is upregulated in DDIT3- and FUS-DDIT3-expressing fibrosarcoma cell lines and in myxoid liposarcoma cell lines...
  4. Cheng H, Dodge J, Mehl E, Liu S, Poulin N, van de Rijn M, et al. Validation of immature adipogenic status and identification of prognostic biomarkers in myxoid liposarcoma using tissue microarrays. Hum Pathol. 2009;40:1244-51 pubmed publisher
    b>Myxoid liposarcoma displays variably aggressive behavior and responds poorly to available systemic therapies...
  5. Conill C, Setoain X, Colomo L, Palacin A, Combalia Aleu A, Pomes J, et al. Diagnostic efficacy of bone scintigraphy, magnetic resonance imaging, and positron emission tomography in bone metastases of myxoid liposarcoma. J Magn Reson Imaging. 2008;27:625-8 pubmed publisher
    ..Thus, because of the heterogeneous histological features of MLS and the biological behavior of the disease, a combined approach of FDGPET-CT and MRI, may allow a more accurate staging of soft tissue sarcomas...
  6. Panagopoulos I, Mertens F, Isaksson M, Mandahl N. A novel FUS/CHOP chimera in myxoid liposarcoma. Biochem Biophys Res Commun. 2000;279:838-45 pubmed
    The cytogenetic hallmark of myxoid liposarcoma is the chromosomal aberration t(12;16)(q13;p11), which is pathognomonic for this tumor type...
  7. Nishida Y, Tsukushi S, Nakashima H, Ishiguro N. Clinicopathologic prognostic factors of pure myxoid liposarcoma of the extremities and trunk wall. Clin Orthop Relat Res. 2010;468:3041-6 pubmed publisher
    b>Myxoid liposarcoma is generally considered a low grade tumor but the presence of areas of round cells exceeding 5% is reportedly associated with a worse prognosis...
  8. Negri T, Virdis E, Brich S, Bozzi F, Tamborini E, Tarantino E, et al. Functional mapping of receptor tyrosine kinases in myxoid liposarcoma. Clin Cancer Res. 2010;16:3581-93 pubmed publisher
  9. Ohguri T, Hisaoka M, Kawauchi S, Sasaki K, Aoki T, Kanemitsu S, et al. Cytogenetic analysis of myxoid liposarcoma and myxofibrosarcoma by array-based comparative genomic hybridisation. J Clin Pathol. 2006;59:978-83 pubmed
    ..To investigate overall chromosomal alterations using array-based comparative genomic hybridisation (CGH) of myxoid liposarcomas (MLSs) and myxofibrosarcomas (MFSs)...
  10. Olofsson A, Willen H, Göransson M, Engström K, Meis Kindblom J, Stenman G, et al. Abnormal expression of cell cycle regulators in FUS-CHOP carrying liposarcomas. Int J Oncol. 2004;25:1349-55 pubmed
    ..We conclude that deregulation of G1 controlling proteins is common in MLS/RCLS and that aberrant expression of these proteins is of importance in the pathogenesis of this tumor type...
  11. Antonescu C, Tschernyavsky S, Decuseara R, Leung D, Woodruff J, Brennan M, et al. Prognostic impact of P53 status, TLS-CHOP fusion transcript structure, and histological grade in myxoid liposarcoma: a molecular and clinicopathologic study of 82 cases. Clin Cancer Res. 2001;7:3977-87 pubmed
    ..We also analyzed P53 status, because this parameter has been found to have a significant prognostic impact in other sarcomas with chromosomal translocations...
  12. Chung P, Deheshi B, Ferguson P, Wunder J, Griffin A, Catton C, et al. Radiosensitivity translates into excellent local control in extremity myxoid liposarcoma: a comparison with other soft tissue sarcomas. Cancer. 2009;115:3254-61 pubmed publisher
    b>Myxoid liposarcoma has been reported to be more radiosensitive compared with other soft tissue sarcomas (STS)...
  13. Kuroda M, Wang X, Sok J, Yin Y, Chung P, Giannotti J, et al. Induction of a secreted protein by the myxoid liposarcoma oncogene. Proc Natl Acad Sci U S A. 1999;96:5025-30 pubmed
    ..TLS-CHOP thus leads to the unscheduled expression of a gene that is normally associated with adipocytic differentiation...
  14. Guadagnolo B, Zagars G, Ballo M, Patel S, Lewis V, Benjamin R, et al. Excellent local control rates and distinctive patterns of failure in myxoid liposarcoma treated with conservation surgery and radiotherapy. Int J Radiat Oncol Biol Phys. 2008;70:760-5 pubmed
    To evaluate the local control rates and patterns of metastatic relapse in patients with localized myxoid liposarcoma treated with conservation surgery and radiotherapy (RT).
  15. Elwood H, Parwani A, Cai G. Fine-needle aspiration biopsy of myxoid liposarcoma metastatic to the liver: cytomorphologic and cytogenetic features. Diagn Cytopathol. 2007;35:734-7 pubmed
    b>Myxoid liposarcoma has characteristic cytomorphological features and carries a specific cytogenetic abnormality. Here we describe a case of myxoid liposarcoma metastatic to the liver, which was diagnosed by fine-needle aspiration biopsy...
  16. Bode Lesniewska B, Frigerio S, Exner U, Abdou M, Moch H, Zimmermann D. Relevance of translocation type in myxoid liposarcoma and identification of a novel EWSR1-DDIT3 fusion. Genes Chromosomes Cancer. 2007;46:961-71 pubmed
    ..Since the total number of patients is still limited, further studies are required to verify a putative association of type I FUS/DDIT3-fusion transcripts with a prognosis of MRCL...
  17. Tysome J, Sandison A, Clarke P. Myxoid liposarcoma metastatic to the thyroid gland: a case report and literature review. J Laryngol Otol. 2006;120:511-3 pubmed
    We present the second reported case of a myxoid liposarcoma metastatic to the thyroid gland in a 51-year-old gentleman with previous liposarcoma of the right thigh...
  18. Sheah K, Ouellette H, Torriani M, Nielsen G, Kattapuram S, Bredella M. Metastatic myxoid liposarcomas: imaging and histopathologic findings. Skeletal Radiol. 2008;37:251-8 pubmed
    ..The objective was to describe the imaging and histopathologic characteristics of metastatic myxoid liposarcomas...
  19. Silvagni L, Eibenstein A, Chiti Batelli S, Hueck S, Fusetti M. Myxoid liposarcoma of the oral cavity: case report and review of the literature. Acta Otolaryngol. 2001;121:759-62 pubmed
    ..Complete surgical excision is the most effective treatment. We present a case of myxoid liposarcoma of the cheek, together with a literature review of intraoral liposarcomas reported during the last 60 years.
  20. Ogose A, Hotta T, Inoue Y, Sakata S, Takano R, Yamamura S. Myxoid liposarcoma metastatic to the thoracic epidural space without bone involvement: report of two cases. Jpn J Clin Oncol. 2001;31:447-9 pubmed
    b>Myxoid liposarcoma can frequently metastasize to extrapulmonary sites. We present two cases of myxoid liposarcoma metastatic to the epidural space. Both patients complained of back pain, but plain radiography revealed no abnormality...
  21. Carboni F, Ettorre G, Lorusso R, Lepiane P, Santoro R, Mancini P, et al. Isolated pancreatic metastasis of extremity myxoid liposarcoma: Report of a case. Jpn J Clin Oncol. 2006;36:662-4 pubmed
    b>Myxoid liposarcoma (ML) has a high predilection for extrapulmonary sites of metastases, including intra-abdominal metastases, but pancreatic involvement is extremely rare...
  22. Tirabosco R, Arora R, Ye H, Brunell C, Halai D, Flanagan A. Primary myxoid liposarcoma of the ovary in an adolescent girl: a case report. Int J Gynecol Pathol. 2010;29:256-9 pubmed publisher
    ..Histologic examination showed a malignant myxoid tumor with chicken-wire vasculature characteristic of a myxoid liposarcoma. The morphologic appearances were supported by the presence of the rearrangement of the CHOP gene ..
  23. Engström K, Willen H, Kåbjörn Gustafsson C, Andersson C, Olsson M, Göransson M, et al. The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma cells. Am J Pathol. 2006;168:1642-53 pubmed
    ..In addition, development of lipoblasts and the typical MLS/RCLS capillary network could be an effect of the DDIT3 transcription factor partner of the fusion oncogene...
  24. Pantanowitz L, Otis C. Myxoid liposarcoma. Diagn Cytopathol. 2007;35:283-4 pubmed
  25. Thelin Järnum S, Lassen C, Panagopoulos I, Mandahl N, Aman P. Identification of genes differentially expressed in TLS-CHOP carrying myxoid liposarcomas. Int J Cancer. 1999;83:30-3 pubmed
    ..MLAT1, 2 and 6 show high similarity to glia-derived nexin, neuronatin and the RET oncogene, respectively, all normally involved in development of tissues of neural origin. MLAT3 to MLAT5 represent new genes...
  26. Rapp T, Yang L, Conrad E, Mandahl N, Chansky H. RNA splicing mediated by YB-1 is inhibited by TLS/CHOP in human myxoid liposarcoma cells. J Orthop Res. 2002;20:723-9 pubmed
    Human myxoid liposarcoma contains a characteristic t(12;16) chromosomal translocation that results in fusion of the N-terminal domain of the translocated in liposarcoma (TLS) protein to the C/EBP homologous protein (CHOP)...
  27. Bengezi O, Kearns R, Shuhaibar H, Archibald S. Myxoid liposarcoma of the tongue. J Otolaryngol. 2002;31:327-8 pubmed
  28. Frapolli R, Tamborini E, Virdis E, Bello E, Tarantino E, Marchini S, et al. Novel models of myxoid liposarcoma xenografts mimicking the biological and pharmacologic features of human tumors. Clin Cancer Res. 2010;16:4958-67 pubmed publisher
    b>Myxoid liposarcoma is a common subtype of liposarcoma...
  29. Panagopoulos I, Hoglund M, Mertens F, Mandahl N, Mitelman F, Aman P. Fusion of the EWS and CHOP genes in myxoid liposarcoma. Oncogene. 1996;12:489-94 pubmed
  30. Loubignac F, Bourtoul C, Chapel F. Myxoid liposarcoma: a rare soft-tissue tumor with a misleading benign appearance. World J Surg Oncol. 2009;7:42 pubmed publisher
    ..Multiple histologic subtypes of liposarcoma are recognized, including myxoid liposarcoma, and correspond to tumors of very different prognosis...
  31. Vocks E, Worret W, Burgdorf W. Myxoid liposarcoma in a 12-year-old girl. Pediatr Dermatol. 2000;17:129-32 pubmed
    A 12-year-old girl developed a myxoid liposarcoma on the inner side of her right thigh. Liposarcomas are extremely rare at this age compared to benign lipoblastomas, which are the most frequent tumors of fatty tissue in childhood...
  32. Pilotti S, Lavarino C, Mezzelani A, Della Torre C, Minoletti F, Sozzi G, et al. Limited role of TP53 and TP53-related genes in myxoid liposarcoma. Tumori. 1998;84:571-7 pubmed
    Circumstantial evidence suggests that genetic changes may lead to tumor progression within the myxoid liposarcoma tumors (MLTs) carrying non-random chromosomal translocation t(12;16).
  33. Forni C, Minuzzo M, Virdis E, Tamborini E, Simone M, Tavecchio M, et al. Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma tumors. Mol Cancer Ther. 2009;8:449-57 pubmed publisher
    ..In the case of myxoid liposarcoma (MLS) tumors, the causative abnormality is a fusion between the CHOP transcription factor and the FUS or EWS ..
  34. ten Heuvel S, Hoekstra H, van Ginkel R, Bastiaannet E, Suurmeijer A. Clinicopathologic prognostic factors in myxoid liposarcoma: a retrospective study of 49 patients with long-term follow-up. Ann Surg Oncol. 2007;14:222-9 pubmed
    The main goal of this retrospective study was to investigate prognostic factors influencing the survival of myxoid liposarcoma (MLS) with emphasis on the role of transitional areas (TLS) and round cell morphology (RCLS).
  35. Riggi N, Cironi L, Provero P, Suva M, Stehle J, Baumer K, et al. Expression of the FUS-CHOP fusion protein in primary mesenchymal progenitor cells gives rise to a model of myxoid liposarcoma. Cancer Res. 2006;66:7016-23 pubmed
    ..of EWS-ATF1 and SYT-SSX1 failed to transform MPCs, FUS-CHOP-expressing cells formed tumors resembling human myxoid liposarcoma. Transcription profile analysis of these tumors revealed induction of transcripts known to be associated ..
  36. Daly S, Sciubba J, Tufano R. Lower-extremity liposarcoma metastatic to the larynx: case report. Ear Nose Throat J. 2006;85:185-6, 189 pubmed
    ..He was found to have a laryngeal lesion that was consistent with a primary myxoid liposarcoma that had been extirpated from a lower extremity earlier To the best of our knowledge, no case of myxoid ..
  37. Thelin Järnum S, Göransson M, Burguete A, Olofsson A, Aman P. The myxoid liposarcoma specific TLS-CHOP fusion protein localizes to nuclear structures distinct from PML nuclear bodies. Int J Cancer. 2002;97:446-50 pubmed
    ..Transfection of TLS-CHOP induced a rapid disappearance of PCNA. TLS-CHOP may disturb the nuclear machinery by binding and sequestering important factors from their natural sites...
  38. Goransson M, Andersson M, Forni C, Stahlberg A, Andersson C, Olofsson A, et al. The myxoid liposarcoma FUS-DDIT3 fusion oncoprotein deregulates NF-kappaB target genes by interaction with NFKBIZ. Oncogene. 2009;28:270-8 pubmed publisher
    ..Similar mechanisms may be a part of the transformation process in other tumor types carrying FUS, EWSR1 and TAF15 containing fusion oncogenes...
  39. Germano G, Frapolli R, Simone M, Tavecchio M, Erba E, Pesce S, et al. Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells. Cancer Res. 2010;70:2235-44 pubmed publisher
    ..Patients with myxoid liposarcoma (MLS), a subtype characterized by the expression of the oncogenic transcript FUS-CHOP, are highly responsive ..
  40. Fairman E, Mauro V, Cianciulli T, Rubio M, Charask A, Bustamante J, et al. Liposarcoma causing left ventricular outflow tract obstruction and syncope: a case report and review of the literature. Int J Cardiovasc Imaging. 2005;21:513-8 pubmed
    Metastatic cardiac myxoid liposarcoma is rare...
  41. Hannachi Sassi S, Braham E, Bhouri L, Mrad K, Abbes I, Driss M, et al. [Orbital metastasis of liposarcoma]. J Fr Ophtalmol. 2007;30:e28 pubmed
    ..A 57-year-old man with a history 5 years before of myxoid liposarcoma on the right calf, completely surgically resected, was admitted for recent proptosis of the left eye...
  42. Okuda I, Ubara Y, Okuda C, Fujii T, Suwabe T, Kokubo T, et al. A large calcified retroperitoneal mass in a patient with chronic renal failure: liposarcoma with ossification. Clin Exp Nephrol. 2010;14:185-9 pubmed publisher
  43. Ratan R, Patel S. Trabectedin and Eribulin: Where Do They Fit in the Management of Soft Tissue Sarcoma?. Curr Treat Options Oncol. 2017;18:34 pubmed publisher
    ..The sequencing of trabectedin with other agents is also worth examining. In a disease like myxoid liposarcoma, consideration should be given to using trabectedin before other salvage regimens like gemcitabine and ..
  44. Ehara S, Rosenberg A, Kattapuram S. Atypical lipomas, liposarcomas, and other fat-containing sarcomas. CT analysis of fat element. Clin Imaging. 1995;19:50-3 pubmed
    ..The radiographic appearance of fat in and around soft tissue sarcomas was evaluated to assess the diagnostic potential of this finding. Based on the distribution of fat and other components, these tumors are classified into three types...
  45. Thompson S, Duque C, Sheth R, Casiano R, Morcos J, Gomez Fernandez C. Case report: Liposarcoma of the sinonasal tract. Br J Radiol. 2009;82:e160-3 pubmed publisher
  46. Kooy H, Clasie B, Lu H, Madden T, Bentefour H, Depauw N, et al. A case study in proton pencil-beam scanning delivery. Int J Radiat Oncol Biol Phys. 2010;76:624-30 pubmed publisher
    ..PBS offers improved dose distributions, reduced treatment time, and reduced cost of treatment. ..
  47. Silverman J, Hamilton J, Tamsen A. Benign recurring lipoblastoma in an adult versus well differentiated subcutaneous myxoid liposarcoma: clinicopathologic, immunohistochemical and molecular analysis of a unique case. Pathol Res Pract. 1999;195:787-92; discussion 793 pubmed
    Subcutaneous myxoid liposarcoma (ML) is exceedingly rare, with only two or three cases having been reported. Lipoblastoma (LB), a rare fatty tumor that arises in infants and children, is unknown after adolescence...
  48. Huang H, Antonescu C. Molecular variability of TLS-CHOP structure shows no significant impact on the level of adipogenesis: a comparative ultrastructural and RT-PCR analysis of 14 cases of myxoid/round cell liposarcomas. Ultrastruct Pathol. 2003;27:217-26 pubmed
    ..These findings cannot substantiate the hypothesis that the molecular variability of fusion transcripts has a biological impact on adipogenesis of MLS, and other factors might be implicated in their level of differentiation. ..
  49. Künstlinger H, Fassunke J, Schildhaus H, Brors B, Heydt C, Ihle M, et al. FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitro. Oncotarget. 2015;6:20215-30 pubmed
    ..Treatment of the myxoid liposarcoma cell lines MLS 402 and MLS 1765 with the FGFR inhibitors PD173074, TKI258 (dovitinib) and BGJ398 as well as ..
  50. Matsumoto M, Suehiro K, Kubo K, Tsushima Y, Yoshitaka H, Kuinose M, et al. [Giant cardiac metastasis of myxoid liposarcoma causing cardiac tamponade; report of a case]. Kyobu Geka. 2007;60:65-8 pubmed
    We report a very rare case of cardiac metastasis of myxoid liposarcoma. A 55-year-old man presented with dyspnea. Two and a half years ago, he underwent resection of myxoid liposarcoma in the left thigh...
  51. Das G, Das B. Giant lesser sac liposarcoma mimicking infected pancreatic pseudocyst. Indian J Gastroenterol. 2006;25:157-8 pubmed
    ..We report a 32-year-old man with lesser-sac myxoid liposarcoma with extensive cystic degeneration...
  52. Schaad K, Strombeck B, Mandahl N, Andersen M, Heim S, Mertens F, et al. FISH mapping of i(7q) in acute leukemias and myxoid liposarcoma reveals clustered breakpoints in 7p11.2: implications for formation and pathogenetic outcome of the idic(7)(p11.2). Cytogenet Genome Res. 2006;114:126-30 pubmed
    ..The pathogenetically important outcome is thus likely to be an altered gene expression because of copy number changes. The clustering of breakpoints might be due to frequent intrachromosomal duplicons in the BP region. ..
  53. Schneider Stock R, Walter H, Rys J, Radig K, Hoang Vu C, Roessner A. No correlation of c-myc overexpression and p53 mutations in liposarcomas. Virchows Arch. 1998;433:315-21 pubmed
    ..Our results indicate that the c-myc oncogene and the p53 tumor suppressor gene do not seem to cooperate in the oncogenesis of liposarcomas...
  54. Alaggio R, Coffin C, Weiss S, Bridge J, Issakov J, Oliveira A, et al. Liposarcomas in young patients: a study of 82 cases occurring in patients younger than 22 years of age. Am J Surg Pathol. 2009;33:645-58 pubmed publisher
    ..Six cases showed myxoid liposarcoma with spindled growth ("spindle cell myxoid liposarcoma"); these arose in 5 females and 1 male (..
  55. Vassilopoulos P, Voros D, Kelessis N, Katsilieris J, Apostolikas N. Unusual spread of liposarcoma. Anticancer Res. 2001;21:1419-21 pubmed
    ..The aim of our study was to investigate the unusual pattern of metastatic spread of liposarcoma...
  56. Wu J, Montgomery E. Classification and pathology. Surg Clin North Am. 2008;88:483-520, v-vi pubmed publisher
    ..In this article the lesions are described essentially in accordance with the World Health Organization classification...
  57. Awad W, Rhys Evans P, Nicholson A, Goldstraw P. Liposarcoma of the thyroid gland mimicking retrosternal goiter. Ann Thorac Surg. 2003;75:566-8 pubmed
    ..Patient 2 had a long-term history of benign goiter, a previous partial thyroidectomy, and more recent biopsies showing liposarcoma. The management of such rare conditions is always challenging...
  58. Tsirbas A, Kazim M, Close L. Endoscopic approach to orbital apex lesions. Ophthalmic Plast Reconstr Surg. 2005;21:271-5 pubmed
    ..To examine the role of transnasal and transantral endoscopic surgical approaches in the management of apical orbital lesions...
  59. Tomita H, Yamaguchi K, Matsuo M, Ohno T, Nishimoto Y, Hirose Y. Metastatic myxoid liposarcoma in the mesentery: what is debated? Case report and a review of the literature. Am Surg. 2006;72:68-70 pubmed
    b>Myxoid liposarcoma, unlike other types of liposarcoma, has an unusual propensity to metastasize to extrapulmonary sites including the abdominal cavity...
  60. Singh N, Kolluri R. Liposarcoma of thigh presenting as deep venous thrombosis. Phlebology. 2009;24:139-41 pubmed publisher
    ..To discuss the differential diagnosis of a case with leg swelling and pain with special emphasis on soft-tissue malignancy...
  61. Xiang H, Wang J, Hisaoka M, Zhu X. Characteristic sequence motifs located at the genomic breakpoints of the translocation t(12;16) and t(12;22) in myxoid liposarcoma. Pathology. 2008;40:547-52 pubmed publisher
    ..To analyse the characteristic sequence motifs around genomic breakpoints of translocations, t(12;16) and t(12;22), and to study the mechanisms underlying these chromosomal translocations in myxoid liposarcomas (MLS)...
  62. Wu T, Tarn J. Vulvar myxoid liposarcoma. Taiwan J Obstet Gynecol. 2007;46:293-4 pubmed
  63. Kim H, Park S, Chi J. Aggressive angiomyxoma of childhood: two unusual cases developed in the scrotum. Pediatr Dev Pathol. 2003;6:187-91 pubmed
    ..Both lesions typically showed infiltrating borders and penetrated into skin adnexa and Dartos' muscle fibers. AAM should be considered in the differential diagnosis of a scrotal mass found in childhood...
  64. Tosson R, Krismann M. Primary myxoid sarcoma of the pleura: 5 years follow-up. Thorac Cardiovasc Surg. 2000;48:238-40 pubmed
    ..Pleuropneumonectomy was done. Four years after the first excision further tumour masses appeared above the diaphragm and were surgically removed and adjuvant irradiation carried out. A year later the patient is doing well...
  65. Sobral A, de Oliveira Lima D, Cazal C, Santiago T, das Graças Granja Mattos M, Melo B, et al. Myxoid liposarcoma of the lip: correlation of histological and cytological features and review of the literature. J Oral Maxillofac Surg. 2007;65:1660-4 pubmed
  66. Panagopoulos I, Mandahl N, Ron D, Hoglund M, Nilbert M, Mertens F, et al. Characterization of the CHOP breakpoints and fusion transcripts in myxoid liposarcomas with the 12;16 translocation. Cancer Res. 1994;54:6500-3 pubmed
    ..As a consequence the normally nontranslated exon 2 is translated and in both types there is in the junction between FUS and CHOP a shift from a FUS glycine codon to a valine codon in the chimeric mRNA...