angiomyolipoma

Summary

Summary: A benign tumor containing vascular, adipose, and muscle elements. It occurs most often in the kidney with smooth muscle elements (angiolipoleiomyoma) in association with tuberous sclerosis. (Dorland, 27th ed)

Top Publications

  1. Lane B, Aydin H, Danforth T, Zhou M, Remer E, Novick A, et al. Clinical correlates of renal angiomyolipoma subtypes in 209 patients: classic, fat poor, tuberous sclerosis associated and epithelioid. J Urol. 2008;180:836-43 pubmed publisher
    ..Histologically confirmed angiomyolipomas uniformly follow a benign course but rare epithelioid variants of angiomyolipoma can recur and metastasize...
  2. Gregory S, Anderson C, Patel U. Radiofrequency ablation of large renal angiomyolipoma: median-term follow-up. Cardiovasc Intervent Radiol. 2013;36:682-9 pubmed publisher
    ..RFA of large AMLs is technically feasible using saline-infused electrodes. The soft-tissue elements decreased in volume; the tumors become fattier; and there has been no renal haemorrhage during a 48-month period. ..
  3. Paul E, Thiele E. Efficacy of sirolimus in treating tuberous sclerosis and lymphangioleiomyomatosis. N Engl J Med. 2008;358:190-2 pubmed publisher
  4. Lenton J, Kessel D, Watkinson A. Embolization of renal angiomyolipoma: immediate complications and long-term outcomes. Clin Radiol. 2008;63:864-70 pubmed publisher
    To report the outcomes of elective and emergency embolization of renal angiomyolipoma and describe an angiographic sign that will help localize the symptomatic aneurysm in emergency cases...
  5. Petrolla A, Xin W. Hepatic angiomyolipoma. Arch Pathol Lab Med. 2008;132:1679-82 pubmed publisher
    Hepatic angiomyolipoma is a rare, benign, hepatic mesenchymal neoplasm found in both males and females, and most commonly in adult females. Angiomyolipoma occurs most commonly in the kidneys...
  6. D Antonio A, Caleo A, Caleo O, De Dominicis G, Boscaino A. Monotypic epithelioid angiomyolipoma of the adrenal gland: an unusual site for a rare extrarenal tumor. Ann Diagn Pathol. 2009;13:347-50 pubmed publisher
    Epithelioid angiomyolipoma (AML) is an uncommon renal mesenchymal tumor with malignant potential and is frequently associated with tuberous sclerosis...
  7. Dabora S, Franz D, Ashwal S, Sagalowsky A, DiMario F, Miles D, et al. Multicenter phase 2 trial of sirolimus for tuberous sclerosis: kidney angiomyolipomas and other tumors regress and VEGF- D levels decrease. PLoS ONE. 2011;6:e23379 pubmed publisher
    ..Tuberous sclerosis (TSC) related tumors are characterized by constitutively activated mTOR signaling due to mutations in TSC1 or TSC2...
  8. Froemming A, Boland J, Cheville J, Takahashi N, Kawashima A. Renal epithelioid angiomyolipoma: imaging characteristics in nine cases with radiologic-pathologic correlation and review of the literature. AJR Am J Roentgenol. 2013;200:W178-86 pubmed publisher
    The purpose of this study was to describe the imaging features of renal epithelioid angiomyolipoma (EAML), a rare subtype of angiomyolipoma, with clinical and pathologic correlation.
  9. Zhang Y, Luo S, Liu Y, Xu R. Angiomyolipoma with minimal fat: differentiation from papillary renal cell carcinoma by helical CT. Clin Radiol. 2013;68:365-70 pubmed publisher
    ..05 for all). The unenhanced attenuation characteristic, intra-tumoural vessels, and the attenuation values of unenhanced and early excretory phase scans are valuable parameters in differentiating AML with minimal fat from PRCC at CT. ..

More Information

Publications83

  1. Kochhar R, Brown R, Wong C, Dunnick N, Frey K, Manoharan P. Role of FDG PET/CT in imaging of renal lesions. J Med Imaging Radiat Oncol. 2010;54:347-57 pubmed publisher
    ..The lesions discussed include renal cyst, angiomyolipoma, oncocytoma, renal cell carcinoma, renal metastases and other infiltrating neoplastic processes affecting the ..
  2. Shi H, Cao D, Wei L, Sun L, Guo A. Inflammatory angiomyolipomas of the liver: a clinicopathologic and immunohistochemical analysis of 5 cases. Ann Diagn Pathol. 2010;14:240-6 pubmed publisher
    Hepatic angiomyolipoma (AML) may demonstrate a marked histologic diversity. We report 5 cases of hepatic AML exhibiting prominent inflammatory cells in the background (inflammatory AML)...
  3. Bissler J, McCormack F, Young L, Elwing J, Chuck G, Leonard J, et al. Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis. N Engl J Med. 2008;358:140-51 pubmed publisher
    ..We conducted a 24-month, nonrandomized, open-label trial to determine whether sirolimus reduces the angiomyolipoma volume in patients with the tuberous sclerosis complex or sporadic lymphangioleiomyomatosis...
  4. Chen P, Yuan T, Liu H. Hepatic angiomyolipoma mimicking hepatic clear cell carcinoma. J Int Med Res. 2009;37:257-63 pubmed
    b>Angiomyolipoma usually involves the kidney and rarely affects the liver. This study reports a case of angiomyolipoma of the liver in a 47-year-old Chinese woman. The patient did not present with abdominal pain and jaundice...
  5. Clements D, Markwick L, Puri N, Johnson S. Role of the CXCR4/CXCL12 axis in lymphangioleiomyomatosis and angiomyolipoma. J Immunol. 2010;185:1812-21 pubmed publisher
    ..a progressive disease caused by accumulation of metastatic (LAM) cells in the lungs, lymphatics, and the tumor angiomyolipoma (AML)...
  6. Clements D, Asprey S, McCulloch T, Morris T, Watson S, Johnson S. Analysis of the oestrogen response in an angiomyolipoma derived xenograft model. Endocr Relat Cancer. 2009;16:59-72 pubmed publisher
    ..b>Angiomyolipoma and LAM are caused by loss of function of either the tuberous sclerosis-1 or -2 genes resulting in activation ..
  7. Staehler M, Sauter M, Helck A, Linsenmaier U, Weber L, Mayer K, et al. Nephron-sparing resection of angiomyolipoma after sirolimus pretreatment in patients with tuberous sclerosis. Int Urol Nephrol. 2012;44:1657-61 pubmed publisher
    Renal angiomyolipoma in patients with tuberous sclerosis can cause life-threatening bleeding. Embolization or resection is recommended, but either intervention may result in substantial loss of renal function...
  8. Xu Z, Xu H, Xie X, Liu G, Zheng Y, Lu M. Renal cell carcinoma and renal angiomyolipoma: differential diagnosis with real-time contrast-enhanced ultrasonography. J Ultrasound Med. 2010;29:709-17 pubmed
    The purpose of this study was to evaluate the usefulness of contrast-enhanced ultrasonography (CEUS) in differentiating renal cell carcinoma (RCC) from renal angiomyolipoma (RAML).
  9. Ricketts R, Tamboli P, Czerniak B, Guo C. Tumor-to-tumor metastasis: report of 2 cases of metastatic carcinoma to angiomyolipoma of the kidney. Arch Pathol Lab Med. 2008;132:1016-20 pubmed publisher
    ..However, renal angiomyolipoma has not been reported to be a recipient...
  10. Kato I, Inayama Y, Yamanaka S, Ohshiro H, Gomi K, Shirai S, et al. Epithelioid angiomyolipoma of the kidney. Pathol Int. 2009;59:38-43 pubmed publisher
    Epithelioid angiomyolipoma (eAMLoma) is an uncommon renal mesenchymal tumor with malignant potential and is frequently associated with tuberous sclerosis (TSC)...
  11. Rosenkrantz A, Hecht E, Taneja S, Melamed J. Angiomyolipoma with epithelial cysts: mimic of renal cell carcinoma. Clin Imaging. 2010;34:65-8 pubmed publisher
    b>Angiomyolipoma with epithelial cysts (AMLEC) is a rare variant of angiomyolipoma with minimal fat that contains epithelial-lined cysts and may mimic a cystic renal cell carcinoma...
  12. Durgun Y, Firat C, Miman M, Kirimlioglu H. A rare benign laryngeal tumor: angiomyolipoma. J Craniofac Surg. 2010;21:1956-7 pubmed publisher
    b>Angiomyolipoma is a mesenchymal neoplasm containing adipose tissue, blood vessels, and smooth muscle fibers. Arising most frequently in the kidney, the tumor may exceptionally be at the head and neck region...
  13. Tan S, Ozcan M, Tezcan F, Balci S, Karaoglanoglu M, Huddam B, et al. Real-time elastography for distinguishing angiomyolipoma from renal cell carcinoma: preliminary observations. AJR Am J Roentgenol. 2013;200:W369-75 pubmed publisher
    ..The objective of this study was to determine the diagnostic performance of sonoelastography for differentiating angiomyolipomas from renal cell carcinomas...
  14. Nakamura N, Kudo A, Ito K, Tanaka S, Arii S. A hepatic lipoma mimicking angiomyolipoma of the liver: report of a case. Surg Today. 2009;39:825-8 pubmed publisher
    ..This report presents a case of lipoma of the liver mimicking angiomyolipoma. The patient was a 38-year-old man, who was hospitalized without any symptoms after a medical check...
  15. Seyam R, Bissada N, Kattan S, Mokhtar A, Aslam M, Fahmy W, et al. Changing trends in presentation, diagnosis and management of renal angiomyolipoma: comparison of sporadic and tuberous sclerosis complex-associated forms. Urology. 2008;72:1077-82 pubmed publisher
    To evaluate the changing management of sporadic renal angiomyolipoma and renal angiomyolipoma associated with the tuberous sclerosis complex (TSC) during the past 16 years.
  16. Mete O, van der Kwast T. Epithelioid angiomyolipoma: a morphologically distinct variant that mimics a variety of intra-abdominal neoplasms. Arch Pathol Lab Med. 2011;135:665-70 pubmed publisher
    ..the histopathologic, immunohistochemical, ultrastructural, and molecular biologic features of epithelioid angiomyolipoma (EAML), with an emphasis on the differential diagnosis of intra-abdominal EAML...
  17. Martignoni G, Pea M, Reghellin D, Zamboni G, Bonetti F. PEComas: the past, the present and the future. Virchows Arch. 2008;452:119-32 pubmed
    ..There are some open questions about PEComas regarding its histogenesis, the definition of epithelioid angiomyolipoma and the identification of the histological criteria of malignancy...
  18. Boivin B, Zhang S, Arbiser J, Zhang Z, Tonks N. A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells. Proc Natl Acad Sci U S A. 2008;105:9959-64 pubmed publisher
    ..this cysteinyl-labeling assay to the study of platelet-derived growth factor (PDGF) receptor signaling in an angiomyolipoma cell model...
  19. Sasiwimonphan K, Takahashi N, Leibovich B, Carter R, Atwell T, Kawashima A. Small (<4 cm) renal mass: differentiation of angiomyolipoma without visible fat from renal cell carcinoma utilizing MR imaging. Radiology. 2012;263:160-8 pubmed publisher
    ..To determine whether a combination of magnetic resonance (MR) parameters can help differentiate small angiomyolipomas (AMLs) without visible fat from renal cell carcinomas (RCCs)...
  20. Boorjian S, Frank I, Inman B, Lohse C, Cheville J, Leibovich B, et al. The role of partial nephrectomy for the management of sporadic renal angiomyolipoma. Urology. 2007;70:1064-8 pubmed
    b>Angiomyolipoma is a benign renal tumor that has a propensity to grow over time and may cause local complications. Given the benign nature of these lesions, renal-preserving treatments are favored...
  21. Takanami K, Kaneta T, Hitachi S, Yamada T, Ishida K, Rikiyama T, et al. F-18 FDG PET/CT findings in two patients with hepatic angiomyolipoma with and without intratumoral hemorrhage. Clin Nucl Med. 2010;35:18-21 pubmed publisher
    ..This report demonstrates that benign hepatic AMLs may demonstrate increased FDG uptake if there is hemorrhage and a related inflammatory response...
  22. Singh K, Pai R, Kini H, Kini U. Cutaneous angiomyolipoma. Indian J Pathol Microbiol. 2009;52:242-3 pubmed
    ..This lesion, probably hamartomatous in nature, differs from renal angiomyolipoma in terms of nonassociation with tuberous sclerosis, circumscription, and male predominance...
  23. Hiraki T, Mimura H, Gobara H, Fujiwara H, Iguchi T, Sakurai J, et al. Pulmonary edema as a complication of transcatheter embolization of renal angiomyolipoma in a patient with pulmonary lymphangioleiomyomatosis due to tuberous sclerosis complex. J Vasc Interv Radiol. 2009;20:819-23 pubmed publisher
    ..disorder characterized by seizures, mental retardation, and various hamartomatous lesions, including renal angiomyolipoma (AML) and pulmonary lymphangioleiomyomatosis...
  24. Xu P, Shan Y, Yan F, Ji Y, Ding Y, Zhou M. Epithelioid angiomyolipoma of the liver: cross-sectional imaging findings of 10 immunohistochemically-verified cases. World J Gastroenterol. 2009;15:4576-81 pubmed
    To retrospectively evaluate the computed tomography (CT)/magnetic resonance imaging (MRI) imaging features of epithelioid angiomyolipoma of the liver (Epi-HAML), with pathology as a reference.
  25. Koo K, Kim W, Ham W, Lee J, Ju H, Choi Y. Trends of presentation and clinical outcome of treated renal angiomyolipoma. Yonsei Med J. 2010;51:728-34 pubmed publisher
    The purpose of this study is to set guidelines for the management of renal angiomyolipoma (AML), clinical prognosis according to tumor size, in association with tuberous sclerosis complex (TSC), multiplicity, radiographic finding, and ..
  26. Nese N, Martignoni G, Fletcher C, Gupta R, Pan C, Kim H, et al. Pure epithelioid PEComas (so-called epithelioid angiomyolipoma) of the kidney: A clinicopathologic study of 41 cases: detailed assessment of morphology and risk stratification. Am J Surg Pathol. 2011;35:161-76 pubmed publisher
    ..of the kidney are defined as potentially malignant mesenchymal lesions that are closely related to classic angiomyolipoma. Although approximately 120 cases are published, mostly as case reports with variably used diagnostic criteria,..
  27. Shitara K, Yatabe Y, Mizota A, Sano T, Nimura Y, Muro K. Dramatic tumor response to everolimus for malignant epithelioid angiomyolipoma. Jpn J Clin Oncol. 2011;41:814-6 pubmed publisher
    Malignant epithelioid variant of angiomyolipoma has aggressive characteristics, against which conventional cytotoxic agents have been reported to be disappointingly inactive, and the prognosis of unresectable or recurrent disease is ..
  28. Davenport M, Neville A, Ellis J, Cohan R, Chaudhry H, Leder R. Diagnosis of renal angiomyolipoma with hounsfield unit thresholds: effect of size of region of interest and nephrographic phase imaging. Radiology. 2011;260:158-65 pubmed publisher
    To retrospectively determine the optimal Hounsfield unit threshold and region of interest (ROI) size required to accurately diagnose renal angiomyolipoma (AML) and differentiate it from renal cell carcinoma (RCC).
  29. Bharwani N, Christmas T, Jameson C, Moat N, Sohaib S. Epithelioid angiomyolipoma: imaging appearances. Br J Radiol. 2009;82:e249-52 pubmed publisher
    Epithelioid angiomyolipoma is a recently described rare variant of renal angiomyolipoma. It can occur in patients with or without tuberous sclerosis, and may potentially be malignant...
  30. Khalbuss W, Fischer G, Bazooband A. Imprint cytology of epithelioid hepatic angiomyolipoma: mimicry of hepatocellular carcinoma. Acta Cytol. 2007;51:670-2 pubmed
  31. Davies D, Johnson S, Tattersfield A, Kingswood J, Cox J, McCartney D, et al. Sirolimus therapy in tuberous sclerosis or sporadic lymphangioleiomyomatosis. N Engl J Med. 2008;358:200-3 pubmed publisher
  32. Sato K, Ueda Y, Tachibana H, Miyazawa K, Chikazawa I, Kaji S, et al. Malignant epithelioid angiomyolipoma of the kidney in a patient with tuberous sclerosis: an autopsy case report with p53 gene mutation analysis. Pathol Res Pract. 2008;204:771-7 pubmed publisher
    We report an autopsy case of malignant epithelioid angiomyolipoma in a 36-year-old male tuberous sclerosis patient. He had been diagnosed to have a bilateral renal tumor 20 years previously...
  33. Sooriakumaran P, Gibbs P, Coughlin G, Attard V, Elmslie F, Kingswood C, et al. Angiomyolipomata: challenges, solutions, and future prospects based on over 100 cases treated. BJU Int. 2010;105:101-6 pubmed publisher
    To examine the presentation, management and outcomes of patients with renal angiomyolipoma (AML) over a period of 10 years, at St George's Hospital, London, UK.
  34. Pan C, Chung M, Ng K, Liu C, Wang J, Chai C, et al. Constant allelic alteration on chromosome 16p (TSC2 gene) in perivascular epithelioid cell tumour (PEComa): genetic evidence for the relationship of PEComa with angiomyolipoma. J Pathol. 2008;214:387-93 pubmed
    Perivascular epithelioid cell tumours (PEComas) are a family of tumours including classic angiomyolipoma, lymphangioleiomyomatosis, and clear epithelioid cell tumours reported under a variety of names such as epithelioid angiomyolipoma, ..
  35. Kim J, Kim J, Kim N, Cho K. CT histogram analysis: differentiation of angiomyolipoma without visible fat from renal cell carcinoma at CT imaging. Radiology. 2008;246:472-9 pubmed
    ..evaluate the diagnostic performance of computed tomographic (CT) histogram analysis for differentiating angiomyolipoma (AML) without visible fat from renal cell carcinoma (RCC) at CT, by using pathologic analysis and clinical ..
  36. Bissler J, Kingswood J, Radzikowska E, Zonnenberg B, Frost M, Belousova E, et al. Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial. Lancet. 2013;381:817-24 pubmed
    ..We compared the angiomyolipoma response rate on everolimus with placebo in patients with tuberous sclerosis or sporadic ..
  37. Takebayashi S, Horikawa A, Arai M, Iso S, Noguchi K. Transarterial ethanol ablation for sporadic and non-hemorrhaging angiomyolipoma in the kidney. Eur J Radiol. 2009;72:139-45 pubmed publisher
    ..We evaluated the efficacy and side effects of transarterial ethanol ablation in sporadic and non-hemorrhaging angiomyolipomas (AMLs) in the kidney...
  38. Taveira DaSilva A, Hathaway O, Stylianou M, Moss J. Changes in lung function and chylous effusions in patients with lymphangioleiomyomatosis treated with sirolimus. Ann Intern Med. 2011;154:797-805, W-292-3 pubmed publisher
    ..Intramural Research Program, National Heart, Lung, and Blood Institute, National Institutes of Health. ..
  39. Chaudhry H, Davenport M, Nieman C, Ho L, Neville A. Histogram analysis of small solid renal masses: differentiating minimal fat angiomyolipoma from renal cell carcinoma. AJR Am J Roentgenol. 2012;198:377-83 pubmed publisher
    The objective of our study was to retrospectively determine whether minimal fat renal angiomyolipoma can be differentiated from clear cell or papillary renal cell carcinoma (RCC) in small renal masses using attenuation measurement ..
  40. Castle S, Gorbatiy V, Ekwenna O, Young E, Leveillee R. Radiofrequency ablation (RFA) therapy for renal angiomyolipoma (AML): an alternative to angio-embolization and nephron-sparing surgery. BJU Int. 2012;109:384-7 pubmed publisher
    To show that radiofrequency ablation (RFA) is safe and effective treatment for renal angiomyolipoma (AML). Current treatments to reduce the risk of haemorrhage include tumour extirpation, angio-embolization, or ablative therapy.
  41. Boorjian S, Sheinin Y, Crispen P, Lohse C, Kwon E, Leibovich B. Hormone receptor expression in renal angiomyolipoma: clinicopathologic correlation. Urology. 2008;72:927-32 pubmed publisher
    Although renal angiomyolipoma (AML) occurs more commonly in females than males, the origin of this difference in incidence by sex is unknown...
  42. Lenci I, Angelico M, Tisone G, Orlacchio A, Palmieri G, Pinci M, et al. Massive hepatic angiomyolipoma in a young woman with tuberous sclerosis complex: significant clinical improvement during tamoxifen treatment. J Hepatol. 2008;48:1026-9 pubmed publisher
    ..Because of their slow growth, these tumors are often asymptomatic. Since AMLs express estrogen and progesteron receptors we suggest the possible benefits of tamoxifen for the treatment of liver AMLs...
  43. Prevoo W, van den Bosch M, Horenblas S. Radiofrequency ablation for treatment of sporadic angiomyolipoma. Urology. 2008;72:188-91 pubmed publisher
    Symptomatic angiomyolipoma (AML) and asymptomatic AML larger than 4 cm in size are usually treated with nephron-sparing surgery or arterial embolization...
  44. Ding G, Liu Y, Wu M, Yang G, Yang J, Cong W. Diagnosis and treatment of hepatic angiomyolipoma. J Surg Oncol. 2011;103:807-12 pubmed publisher
    Hepatic angiomyolipoma is more frequently encountered in clinical practice, its diagnosis is difficult, its treatment remains controversial. We review a single-center experience in the treatment of hepatic angiomyolipoma.
  45. Zapardiel I, Delafuente Valero J, Bajo Arenas J. Renal angiomyolipoma during pregnancy: review of the literature. Gynecol Obstet Invest. 2011;72:217-9 pubmed publisher
    The incidence of renal angiomyolipoma (RA) is 0.3% in the general population, and even more infrequent during pregnancy. Pregnancy can increase the risk of rupture, although the causal mechanism is still not clearly defined...
  46. Kim M, Lee J, Cho G, Cho K, Kim J, Kim J. MDCT-based scoring system for differentiating angiomyolipoma with minimal fat from renal cell carcinoma. Acta Radiol. 2013;54:1201-9 pubmed publisher
    ..computed tomography (CT) features of renal cell carcinoma (RCC) are a confusing factor in differentiating angiomyolipoma with minimal fat (AMLmf) from RCC...
  47. Graziano A, Santangelo M, Umana D. Clinical evaluation of epithelioid angiomyolipoma. Ann Ital Chir. 2008;79:135-8 pubmed
    ..Epithelioid angiomyolipomas (AML) of the kidney are malignant tumors with aggressive clinical behavior...
  48. Hao L, Lin C, Tsai S. Spontaneous hemorrhagic angiomyolipoma present with massive hematuria leading to urgent nephrectomy. Am J Emerg Med. 2008;26:249.e3-5 pubmed publisher
    ..An immediate surgery is sometimes required for the hemorrhagic uropathy of renal angiomyolipoma. We present a case with left flank pain and findings of hematuria and pyuria...
  49. Alatassi H, Sahoo S. Epithelioid angiomyolipoma of the liver with striking giant cell component: fine-needle aspiration biopsy findings of a rare neoplasm. Diagn Cytopathol. 2009;37:192-4 pubmed publisher
    b>Angiomyolipoma (AML) is a uncommon benign neoplasm of the liver with cyto- and histologic features similar to the more commonly encountered renal AML...
  50. Lopater J, Daniel L, Akiki A, Boissier R, Lechevallier E, Coulange C. [Renal epithelioid angiomyolipoma]. Prog Urol. 2009;19:457-61 pubmed publisher
    ..Partial nephrectomy or follow-up are the benign entity treatment. Radical nephrectomy eventually followed by doxorubicine or rapamycine treatments are recommended for potentially aggressive and malignant entities...
  51. Ho C, Chen S, Ho K, Chan W, Leung Y, Cheng K, et al. Dual-tracer PET/CT in renal angiomyolipoma and subtypes of renal cell carcinoma. Clin Nucl Med. 2012;37:1075-82 pubmed publisher
    We studied the metabolic characteristics of RCC subtypes and angiomyolipoma with 18F-FDG and 11C-acetate PET/CT.
  52. Yang C, Shen S, Chang Y, Chung H, Wang J, Lin A, et al. Are there useful CT features to differentiate renal cell carcinoma from lipid-poor renal angiomyolipoma?. AJR Am J Roentgenol. 2013;201:1017-28 pubmed publisher
    This study was an attempt to identify key CT features that can potentially be used to differentiate between lipid-poor renal angiomyolipoma and renal cell carcinoma (RCC).
  53. Lee S, Hsu H, Chen Y, Huang C, Wong Y, Wang L, et al. Evaluation of renal function of angiomyolipoma patients after selective transcatheter arterial embolization. Am J Med Sci. 2009;337:103-8 pubmed publisher
    b>Angiomyolipoma patients may have renal insufficiency before selective transcatheter arterial embolization (TAE) or may undergo subsequent surgery after TAE...
  54. Simpfendorfer C, Herts B, Motta Ramirez G, Lockwood D, Zhou M, Leiber M, et al. Angiomyolipoma with minimal fat on MDCT: can counts of negative-attenuation pixels aid diagnosis?. AJR Am J Roentgenol. 2009;192:438-43 pubmed publisher
    The purpose of this study was to determine whether counts of pixels with subzero attenuation on CT scans can aid in the diagnosis of renal angiomyolipoma with minimal fat.
  55. Mikami S, Oya M, Mukai M. Angiomyolipoma with epithelial cysts of the kidney in a man. Pathol Int. 2008;58:664-7 pubmed publisher
    b>Angiomyolipoma (AML) is a well-characterized tumor composed of vascular, smooth muscle and adipose elements. Recently, AML with epithelial cysts (AMLEC) has been described as a cystic variant of AML...
  56. Schachter L, Cookson M, Chang S, Smith J, Dietrich M, Jayaram G, et al. Second prize: frequency of benign renal cortical tumors and histologic subtypes based on size in a contemporary series: what to tell our patients. J Endourol. 2007;21:819-23 pubmed
    ..This study sought to determine the incidence of the various histologic subtypes of renal cortical tumors according to size in a contemporary series of surgically treated patients...
  57. Siroky B, Czyzyk Krzeska M, Bissler J. Renal involvement in tuberous sclerosis complex and von Hippel-Lindau disease: shared disease mechanisms?. Nat Clin Pract Nephrol. 2009;5:143-56 pubmed publisher
    ..This Review summarizes the pathophysiologic and therapeutic overlap between tuberous sclerosis complex and von Hippel-Lindau disease and highlights the results of recent drug trials in these settings...
  58. Pierorazio P, Hyams E, Tsai S, Feng Z, Trock B, Mullins J, et al. Multiphasic enhancement patterns of small renal masses (?4 cm) on preoperative computed tomography: utility for distinguishing subtypes of renal cell carcinoma, angiomyolipoma, and oncocytoma. Urology. 2013;81:1265-71 pubmed publisher
    ..To analyze the enhancement patterns of small renal masses (SRMs) during 4-phase computed tomography (CT) imaging to predict histology...
  59. Boorjian S, Sheinin Y, Crispen P, Lohse C, Leibovich B, Kwon E. T-cell co-regulatory molecule expression in renal angiomyolipoma and pulmonary lymphangioleiomyomatosis. Urology. 2009;74:1359-64 pubmed publisher
    To investigate the expression of B7-H3 and B7-H1 in renal angiomyolipoma (AML) tumors and the related, devastating syndrome of pulmonary lymphangioleiomyomatosis (LAM)...
  60. Peces R, Peces C, Cuesta Lopez E, Pérez Dueñas V, Vega Cabrera C, Azorin S, et al. Low-dose rapamycin reduces kidney volume angiomyolipomas and prevents the loss of renal function in a patient with tuberous sclerosis complex. Nephrol Dial Transplant. 2010;25:3787-91 pubmed publisher
    ..These data suggest that it could be the result of the anti-angiogenic, anti-fibrotic and anti-proliferative effects of rapamycin...
  61. Richmond L, Atri M, Sherman C, Sharir S. Renal cell carcinoma containing macroscopic fat on CT mimics an angiomyolipoma due to bone metaplasia without macroscopic calcification. Br J Radiol. 2010;83:e179-81 pubmed publisher
    ..is significant because standard imaging practice is to classify a renal mass containing intratumoral macroscopic fat that is not associated with calcification, ossification or invasion of perirenal or hilar fat as an angiomyolipoma.
  62. Cheng K, Chang H, Tsai C, Tyan Y, Tsao T. Sonographic appearance of a cholesterol granuloma within a renal epithelioid angiomyolipoma. J Clin Ultrasound. 2011;39:95-8 pubmed publisher
    We present the sonographic characteristics of a rare case of cholesterol granuloma within a renal epithelioid angiomyolipoma (AML) in a 57-year-old woman...
  63. Aydin H, Magi Galluzzi C, Lane B, Sercia L, Lopez J, Rini B, et al. Renal angiomyolipoma: clinicopathologic study of 194 cases with emphasis on the epithelioid histology and tuberous sclerosis association. Am J Surg Pathol. 2009;33:289-97 pubmed publisher
    The majority of renal angiomyolipoma (AML) is sporadic and occasionally it occurs as part of tuberous sclerosis complex (TSC)...
  64. Lu Q, Wang W, Huang B, Li C, Li C. Minimal fat renal angiomyolipoma: the initial study with contrast-enhanced ultrasonography. Ultrasound Med Biol. 2012;38:1896-901 pubmed publisher
    ..0% and 97.2%, respectively. Slow centripetal enhancement in the cortical phase and homogeneous enhancement at peak are main features of CEUS-confirmed solid minimal fat renal AML...
  65. Tanaka H, Yoshida S, Fujii Y, Ishii C, Tanaka H, Koga F, et al. Diffusion-weighted magnetic resonance imaging in the differentiation of angiomyolipoma with minimal fat from clear cell renal cell carcinoma. Int J Urol. 2011;18:727-30 pubmed publisher
    ..to evaluate diffusion-weighted (DW) magnetic resonance imaging (MRI) in differentiating between minimal fat angiomyolipoma (MFAML) and clear cell renal cell carcinoma (CCRCC)...
  66. Brimo F, Robinson B, Guo C, Zhou M, Latour M, Epstein J. Renal epithelioid angiomyolipoma with atypia: a series of 40 cases with emphasis on clinicopathologic prognostic indicators of malignancy. Am J Surg Pathol. 2010;34:715-22 pubmed publisher
    ..This model accurately categorized 78% of clinically malignant and 100% of the clinically benign epithelioid AMLs with atypia...
  67. Halpenny D, Snow A, McNeill G, Torreggiani W. The radiological diagnosis and treatment of renal angiomyolipoma-current status. Clin Radiol. 2010;65:99-108 pubmed publisher
    ..In addition, we discuss current guidelines for follow-up and prophylactic treatment of these lesions, as well as the increasing role that the interventional radiologist has to play in these cases...
  68. Berglund R, Bernstein M, Manion M, Touijer K, Russo P. Incidental angiomyolipoma resected during renal surgery for an enhancing renal mass. BJU Int. 2009;104:1650-4 pubmed publisher
    To review the outcomes of surgery for renal angiomyolipoma (AML, a benign renal neoplasm that often appears as an enhancing renal mass on imaging) removed at a centre that manages AML conservatively, as typically the presence of tumour ..
  69. Tsukada J, Jinzaki M, Yao M, Nagashima Y, Mikami S, Yashiro H, et al. Epithelioid angiomyolipoma of the kidney: radiological imaging. Int J Urol. 2013;20:1105-11 pubmed publisher
    ..To review the imaging findings of renal epithelioid angiomyolipomas...
  70. Davies D, de Vries P, Johnson S, McCartney D, Cox J, Serra A, et al. Sirolimus therapy for angiomyolipoma in tuberous sclerosis and sporadic lymphangioleiomyomatosis: a phase 2 trial. Clin Cancer Res. 2011;17:4071-81 pubmed publisher
    ..This study investigated the efficacy and safety of the mTORC1 inhibitor sirolimus for treatment of renal angiomyolipomas in patients with these disorders...
  71. Corsenca A, Aebersold F, Moch H, Bird P, Weber M, Hofbauer G, et al. Combined nephrectomy and pre-emptive renal transplantation in a tuberous sclerosis patient with angiomyolipoma, renal carcinoma and life-threatening abdominal haemorrhages. Nephrol Dial Transplant. 2007;22:3330-3 pubmed
  72. Qin W, Bajaj V, Malinowska I, Lu X, MacConaill L, Wu C, et al. Angiomyolipoma have common mutations in TSC2 but no other common genetic events. PLoS ONE. 2011;6:e24919 pubmed publisher
    Renal angiomyolipoma are part of the PEComa family of neoplasms, and occur both in association with Tuberous Sclerosis Complex (TSC) and independent of that disorder...
  73. Aron M, Aydin H, Sercia L, Magi Galluzzi C, Zhou M. Renal cell carcinomas with intratumoral fat and concomitant angiomyolipoma: potential pitfalls in staging and diagnosis. Am J Clin Pathol. 2010;134:807-12 pubmed publisher
    ..Our study highlights the potential pitfalls in staging and diagnosis when intratumoral fat or AML is found within RCC...
  74. Morton J, McLean C, Booth S, Snell G, Whitford H. Regression of pulmonary lymphangioleiomyomatosis (PLAM)-associated retroperitoneal angiomyolipoma post-lung transplantation with rapamycin treatment. J Heart Lung Transplant. 2008;27:462-5 pubmed publisher
    ..tomography (CT) scan demonstrated no pulmonary abnormality, but identified a retroperitoneal mass confirmed as angiomyolipoma by CT-guided core biopsy...