adenosarcoma

Summary

Summary: A malignant neoplasm arising simultaneously or consecutively in mesodermal tissue and glandular epithelium of the same part. (Stedman, 25th ed)

Top Publications

  1. Krivak T, Seidman J, McBroom J, MacKoul P, Aye L, Rose G. Uterine adenosarcoma with sarcomatous overgrowth versus uterine carcinosarcoma: comparison of treatment and survival. Gynecol Oncol. 2001;83:89-94 pubmed
    Uterine adenosarcoma with sarcomatous overgrowth (ASSO) is a rare variant of uterine sarcoma first described in 1989...
  2. Manoharan M, Azmi M, Soosay G, Mould T, Weekes A. Mullerian adenosarcoma of uterine cervix: report of three cases and review of literature. Gynecol Oncol. 2007;105:256-60 pubmed
    Mullerian adenosarcoma of the uterine cervix is a rare tumor seen in young women of reproductive age group. It presents as cervical polyps and is a low-grade malignancy with a tendency for local recurrence...
  3. Arici D, Aker H, Yildiz E, Tasyurt A. Mullerian adenosarcoma of the uterus associated with tamoxifen therapy. Arch Gynecol Obstet. 2000;264:105-7 pubmed
    Mullerian adenosarcoma of the uterus is a biphasic tumor exhibiting benign epithelial and malignant stromal component. This tumor may occasionally be associated with tamoxifen therapy which is used as an adjuvant drug for breast carcinoma...
  4. Geisler J, Orr C, Manahan K. Robotically assisted total laparoscopic radical trachelectomy for fertility sparing in stage IB1 adenosarcoma of the cervix. J Laparoendosc Adv Surg Tech A. 2008;18:727-9 pubmed publisher
    ..A 23-year-old woman was found to have a stage IB1 adenosarcoma of the cervix...
  5. Fleming N, Hopkins L, de Nanassy J, Senterman M, Black A. Mullerian adenosarcoma of the cervix in a 10-year-old girl: case report and review of the literature. J Pediatr Adolesc Gynecol. 2009;22:e45-51 pubmed publisher
    Müllerian adenosarcoma is a rare neoplasm usually found in postmenopausal women. It usually presents as a polypoid mass within the endometrium...
  6. Michener C, Simon N. Ovarian conservation in a woman of reproductive age with müllerian adenosarcoma. Gynecol Oncol. 2001;83:424-7 pubmed
    ..We present a reproductive-age woman with a müllerian adenosarcoma and review the literature on conservative surgical management of this class of tumors.
  7. Comunoglu N, Comunoglu C, Başsüllü N, Somunkiran A, Calay Z. Müllerian adenosarcoma with sarcomatous overgrowth of the cervix: unusual large polypoid mass. Ups J Med Sci. 2007;112:67-72 pubmed
    Müllerian adenosarcoma (MS) is a rare neoplasm of uterine cervix composed of benign epithelial and malignant stromal components...
  8. Patrelli T, Silini E, Gizzo S, Berretta R, Franchi L, Thai E, et al. Extragenital Müllerian adenosarcoma with pouch of Douglas location. BMC Cancer. 2011;11:171 pubmed publisher
    ..In 8-10% of cases, these are represented by Müllerian adenosarcoma an extremely rare tumor characterized by a stromal component of usually low-grade malignancy and by a benign ..
  9. Milam M, Atkinson J, Currie J. Adenosarcoma arising in inguinal endometriosis. Obstet Gynecol. 2006;108:753-5 pubmed
    b>Adenosarcoma arising in inguinal endometriosis is a rare clinical entity.

More Information

Publications86

  1. Toyoshima M, Akahira J, Moriya T, Hayakawa S, Yaegashi N. Primary vaginal adenosarcoma with sarcomatous overgrowth. Gynecol Oncol. 2004;95:759-61 pubmed
    ..Primary vaginal adenosarcomas are extremely rare, and typical adenosarcomas are of low malignancy. However, aggressive forms with sarcomatous overgrowth have been reported, those appear to have a poor prognosis...
  2. Soslow R, Ali A, Oliva E. Mullerian adenosarcomas: an immunophenotypic analysis of 35 cases. Am J Surg Pathol. 2008;32:1013-21 pubmed publisher
    ..ER, PR, and CD10 expression was lost in MA-SOs relative to conventional low-grade stromal areas of mullerian/mesodermal adenosarcomas, reflecting the "dedifferentiation" of this component...
  3. Gallardo A, Prat J. Mullerian adenosarcoma: a clinicopathologic and immunohistochemical study of 55 cases challenging the existence of adenofibroma. Am J Surg Pathol. 2009;33:278-88 pubmed publisher
    ..These findings suggest that some of the tumors currently classified as adenofibromas, on the basis of their low mitotic count and lack of significant nuclear atypia, are, in fact, well-differentiated adenosarcomas...
  4. Shi Y, Liu Z, Peng Z, Liu H, Yang K, Yao X. The diagnosis and treatment of Mullerian adenosarcoma of the uterus. Aust N Z J Obstet Gynaecol. 2008;48:596-600 pubmed publisher
    b>Adenosarcoma of the uterus is one of the rare types of gynaecological malignant tumours...
  5. Murugasu A, Miller J, Proietto A, Millar E. Extragenital mullerian adenosarcoma with sarcomatous overgrowth arising in an endometriotic cyst in the pouch of Douglas. Int J Gynecol Cancer. 2003;13:371-5 pubmed
    Mullerian adenosarcoma is a neoplasm composed of benign mullerian epithelium and a sarcomatous stroma. This tumor classically occurs in the endometrium of postmenopausal women and less frequently in the extrauterine genital tract...
  6. D Angelo E, Prat J. Uterine sarcomas: a review. Gynecol Oncol. 2010;116:131-9 pubmed publisher
    ..Currently, there is no consensus on risk factors for adverse outcome. This review summarizes the available clinicopathological data on uterine sarcomas classified by the WHO diagnostic criteria...
  7. Amant F, Schurmans K, Steenkiste E, Verbist L, Abeler V, Tulunay G, et al. Immunohistochemical determination of estrogen and progesterone receptor positivity in uterine adenosarcoma. Gynecol Oncol. 2004;93:680-5 pubmed
    Given the paucity of data regarding hormone dependency, it was the purpose of this study to screen for the presence of estrogen and progesterone receptors in uterine adenosarcoma (UAS).
  8. Ramos P, Ruiz A, Carabias E, Piñero I, Garzon A, Alvarez I. Müllerian adenosarcoma of the cervix with heterologous elements: report of a case and review of the literature. Gynecol Oncol. 2002;84:161-6 pubmed
    Müllerian adenosarcoma (MA) is a rare neoplasm composed of benign epithelial and malignant stromal components...
  9. Shintaku M, Mise Y. Müllerian adenosarcoma with a neuroectodermal component associated with an endometriotic cyst of the ovary: a case report. Pathol Int. 2012;62:271-5 pubmed publisher
    Reported here is a case of Müllerian adenosarcoma of the ovary which contained a primitive neuroectodermal tissue component within the stroma. The adenosarcoma coexisted with clear cell adenocarcinoma in an endometriotic cyst...
  10. Eichhorn J, Young R, Clement P, Scully R. Mesodermal (müllerian) adenosarcoma of the ovary: a clinicopathologic analysis of 40 cases and a review of the literature. Am J Surg Pathol. 2002;26:1243-58 pubmed
    Forty cases of mesodermal adenosarcoma of the ovary occurred in women 30-84 years of age (mean 54 years). Abdominal discomfort and distension were the usual complaints...
  11. McCluggage W. Mullerian adenosarcoma of the female genital tract. Adv Anat Pathol. 2010;17:122-9 pubmed publisher
    Mullerian adenosarcoma is an uncommon, but not rare, mixed tumor containing a neoplastic but benign or mildly atypical epithelial element and a sarcomatous, usually low-grade, stromal component...
  12. del Carmen M, Lovett D, Goodman A. A case of Müllerian adenosarcoma of the uterus treated with liposomal doxorubicin. Gynecol Oncol. 2003;88:456-8 pubmed
    ..We report on a case of uterine a denosarcoma responsive to treatment with liposomal doxorubicin (Doxil)...
  13. Nomura K, Aizawa S, Ushigome S. Adenosarcoma of the uterine corpus associated with ovarian thecoma. Pathol Int. 2001;51:735-8 pubmed
    We describe a case of adenosarcoma of the uterine corpus associated with ovarian thecoma in a 67-year-old woman. The patient underwent surgery under a diagnosis of ovarian carcinoma...
  14. Hines B, Porges R, Mittal K, Muggia F, Curtin J. Use of medroxyprogesterone acetate in the treatment of Müllerian adenosarcoma: a case report. Gynecol Oncol. 2002;85:192-5 pubmed
    ..We report a case of müllerian adenosarcoma arising outside of the uterus from a background of endometriosis treated with a combination of surgical ..
  15. Stern R, Dash R, Bentley R, Snyder M, Haney A, Robboy S. Malignancy in endometriosis: frequency and comparison of ovarian and extraovarian types. Int J Gynecol Pathol. 2001;20:133-9 pubmed
    ..the malignancies most commonly seen in ovaries containing endometriosis, while clear cell adenocarcinoma and adenosarcoma were most commonly seen in conjunction with extraovarian endometriosis...
  16. Picken M, Curry J, Lindgren V, Clark J, Eble J. Metanephric adenosarcoma in a young adult: morphologic, immunophenotypic, ultrastructural, and fluorescence in situ hybridization analyses: a case report and review of the literature. Am J Surg Pathol. 2001;25:1451-7 pubmed
    ..We conclude that the spectrum of metanephric neoplasia should be expanded to include malignant stromal variants, and we propose the term "metanephric adenosarcoma" for the present case.
  17. Giarenis I, Peat D, Nieto J. Combined malignant ovarian tumour consisting of angiosarcoma, adenosarcoma, cystadenofibroma and granulosa cell tumour. J Obstet Gynaecol. 2008;28:121-3 pubmed publisher
  18. Seidman J, Chauhan S. Evaluation of the relationship between adenosarcoma and carcinosarcoma and a hypothesis of the histogenesis of uterine sarcomas. Int J Gynecol Pathol. 2003;22:75-82 pubmed
    ..To elucidate the relationship between carcinosarcoma (malignant mullerian mixed tumor) and adenosarcoma, a series of 26 consecutive endometrial carcinosarcomas was evaluated for the presence of an adenosarcoma-like ..
  19. Tjalma W, Michener C. Mullerian adenosarcoma of the uterus associated with long-term oral contraceptive use. Eur J Obstet Gynecol Reprod Biol. 2005;119:253-4 pubmed
  20. Nezhat C, Malik S, Osias J, Nezhat F, Nezhat C. Laparoscopic management of 15 patients with infiltrating endometriosis of the bladder and a case of primary intravesical endometrioid adenosarcoma. Fertil Steril. 2002;78:872-5 pubmed
    To report laparoscopic management of 15 patients with infiltrative bladder wall endometriosis and to report a case of endometrioid adenosarcoma.
  21. Kanngurn S, Somran J, Art Ong C, Lamlertthon W, Porncharoenpong S. Primary peritoneal adenosarcoma with stromal overgrowth and fetal type cartilage: a case report and literature review. J Med Assoc Thai. 2005;88:849-54 pubmed
    Primary peritoneal adenosarcoma with sarcomatous overgrowth and fetal-type cartilage presented in a 48-year-old female patient is described...
  22. Park H, Park M, Kim Y, Chun S, Ahn J, Kim C, et al. Mullerian adenosarcoma with sarcomatous overgrowth of the cervix presenting as cervical polyp: a case report and review of the literature. Int J Gynecol Cancer. 2004;14:1024-9 pubmed
    An aggressive variant of adenosarcoma, mullerian adenosarcoma with sarcomatous overgrowth (MASO) in the cervix is extremely rare. This variant contains obvious, high-grade sarcoma in addition to a low-grade form...
  23. Jelovsek J, Winans C, Brainard J, Falcone T. Endometriosis of the liver containing mullerian adenosarcoma: case report. Am J Obstet Gynecol. 2004;191:1725-7 pubmed
    ..After failed management with leuprolide acetate, the mass was resected and contained focal areas of mullerian adenosarcoma. This is a rare case of mullerian adenosarcoma that appeared to arise within an endometrioma of the liver.
  24. Sameshima N, Marutsuka K, Tsukino H, Kamoto T, Kono S, Asada Y. So-called 'adenosarcoma' of the kidney a novel adult renal tumor with a cystic appearance. Pathol Int. 2011;61:313-8 pubmed publisher
    ..Because these findings did not coincide with established descriptions of cystic renal neoplasms, we preferred the term, 'adenosarcoma'. This could become a new classification for adult cystic renal tumors.
  25. Recinos Money E, Escobar Alfaro G, Contreras J, Zepeda Castilla E, Parra Torres C, Di Castro P. [Ovarian adenosarcoma with elevated CA125 antigen. Case report and literature review]. Cir Cir. 2008;76:71-5 pubmed
    ..About 50 cases of adenosarcomas of the ovary have been reported. The relationship between adenosarcoma and CA125 has not been described...
  26. Swisher E, Gown A, Skelly M, Ek M, Tamimi H, Cain J, et al. The expression of epidermal growth factor receptor, HER-2/Neu, p53, and Ki-67 antigen in uterine malignant mixed mesodermal tumors and adenosarcoma. Gynecol Oncol. 1996;60:81-8 pubmed
    ..004). Independent characterization of oncogene proteins in the malignant components of these heterogeneous tumors may provide insight into the histogenesis and behavior of these malignancies...
  27. Huang G, Arend R, Sakaris A, Hebert T, Goldberg G. Extragenital adenosarcoma: a case report, review of the literature, and management discussion. Gynecol Oncol. 2009;115:472-5 pubmed publisher
    Müllerian adenosarcoma is a rare mixed epithelial-mesenchymal tumor. An extragenital site of origin and sarcomatous overgrowth are associated with aggressive clinical behavior.
  28. Patel T, Gupta A, Trivedi P, Shah M. Osteoid differentiation in mesodermal (mullerian) adenosarcoma of ovary. J Cancer Res Ther. 2013;9:529-31 pubmed publisher
    ..Mullerian adenosarcoma of ovary with sarcomatous overgrowth (SO) having heterologous component was confirmed...
  29. Dincer A, Timmins P, Pietrocola D, Fisher H, Ambros R. Primary peritoneal mullerian adenosarcoma with sarcomatous overgrowth associated with endometriosis: a case report. Int J Gynecol Pathol. 2002;21:65-8 pubmed
    We report a primary peritoneal mullerian adenosarcoma with sarcomatous overgrowth associated with endometriosis in a 50-year-old female. The tumor formed multiple peritoneal masses occupying the pelvis and subdiaphragmatic space...
  30. Rovirosa A, Ascaso C, Ordi J, Abellana R, Arenas M, Lejárcegui J, et al. Is vascular and lymphatic space invasion a main prognostic factor in uterine neoplasms with a sarcomatous component? A retrospective study of prognostic factors of 60 patients stratified by stages. Int J Radiat Oncol Biol Phys. 2002;52:1320-9 pubmed
    ..Advanced stages had a more aggressive behavior, and there was a higher incidence of poor prognostic factors in these stages. Nevertheless, prospective studies are still needed on prognostic factors and on the best treatment option. ..
  31. Thiel D, Erhard M. Uterine adenosarcoma in a boy with persistent müllerian duct syndrome: first reported case. J Pediatr Surg. 2005;40:e29-31 pubmed
    ..We present imaging, surgical specimen, and surgical pathology of the first documented case of uterine adenosarcoma of a müllerian remnant in a 14-year-old boy with PMDS presenting with gross hematuria and increasing abdominal ..
  32. Ioffe Y, Li A, Walsh C, Karlan B, Leuchter R, Forscher C, et al. Hormone receptor expression in uterine sarcomas: prognostic and therapeutic roles. Gynecol Oncol. 2009;115:466-71 pubmed publisher
    ..Conducting immunohistochemical staining to ascertain ER status may aid with prognostication in this disease. Hormone therapy should be considered in patients with primary and recurrent ER-positive uterine sarcomas. ..
  33. Farhat F, Fakhruddine N. A case of synchronous relapse of breast cancer and uterine müllerian adenosarcoma post tamoxifen in a premenopausal woman. Eur J Gynaecol Oncol. 2008;29:95-7 pubmed
    ..of use of adjuvant tamoxifen with synchronous liver, bone, and lung metastasis of breast cancer with müllerian adenosarcoma. Immunohistochemical stains on the uterine tumor for estrogen and progesterone receptors showed positivity for ..
  34. Mikaelian I, Reavill D, Practice A. Spontaneous proliferative lesions and tumors of the uterus of captive African hedgehogs (Atelerix albiventris). J Zoo Wildl Med. 2004;35:216-20 pubmed
    ..In one animal with adenosarcoma, peritoneal seeding was detected at the time of hysterectomy. Mean survival time was 303 days (n = 10)...
  35. Martin Loeches M, Rius J, Orti R. Uterine sarcoma associated with tamoxifen use: case report. Eur J Gynaecol Oncol. 2003;24:202-3 pubmed
    A case of müllerian adenosarcoma with sarcomatous overgrowth in a postmenopausal 66-year-old female patient after adjuvant tamoxifen treatment for breast carcinoma is described...
  36. Fatnassi R, Amri F. [Adenosarcoma of the uterus: a case report]. J Gynecol Obstet Biol Reprod (Paris). 2005;34:270-2 pubmed
    b>Adenosarcoma of the uterus has two components: a benign epithelial proliferation and a stromal sarcoma...
  37. Tinelli A, Prudenzano R, Malvasi A, Santantonio M, Lorusso V. Emergency endovascular nanopharmacologic treatment in advanced gynecological cancers. Int J Gynecol Cancer. 2010;20:1250-5 pubmed publisher
    ..Even if it requires experience in intervention radiology, it enables the continuation of external radiotherapy without delay and can replace laparotomic or laparoscopic treatment. ..
  38. Bhandare D, Madiwale C, Kothari K, Pandit A, Kane S. Mullerian adenosarcoma of the uterine cervix. Indian J Pathol Microbiol. 2001;44:371-2 pubmed
    ..5% to 1% of all cervical malignancies. This is a report of cervical mullerian adenosarcoma, which was encountered in a hysterectomy performed for prolapse...
  39. Fehmian C, Jones J, Kress Y, Abadi M. Adenosarcoma of the uterus with extensive smooth muscle differentiation: ultrastructural study and review of the literature. Ultrastruct Pathol. 1997;21:73-9 pubmed
    Four cases of Mullerian adenosarcoma were studied by light and electron microscopy and immunohistochemistry. All 4 cases showed the histologic characteristics of adenosarcoma with benign endometrial glands and a malignant stroma...
  40. Van Mieghem T, Abeler V, Moerman P, Verbist L, Vergote I, Amant F. CD10, estrogen and progesterone receptor expression in ovarian adenosarcoma. Gynecol Oncol. 2005;99:493-6 pubmed
    ..Four cases of primary ovarian adenosarcoma were retrieved in our pathology databases...
  41. Lazar R, Straja T, Bratucu B. Uterine adenosarcoma metastasizing to the retroperitoneum. The impact of vascular involvement. J Med Life. 2012;5:145-8 pubmed
    There is little knowledge regarding mullerian adenosarcoma and its metastasizing pattern...
  42. Llabrés Díaz F. Ultrasonography of the medial iliac lymph nodes in the dog. Vet Radiol Ultrasound. 2004;45:156-65 pubmed
    ..More studies need to be performed, both with patients with reactive lymph nodes and also focusing on other canine superficial lymph nodes, before generalizing the results of this study to other areas or diseases...
  43. Zamecnik M, Sosna B, Chlumska A. Gastrointestinal stromal tumor (GIST) with glandular component. A report of an unusual tumor resembling adenosarcoma. Cesk Patol. 2005;41:150-6 pubmed
    ..The tumor was found in the gastric fundus of a 93-year-old woman. Histologically, the lesion showed a biphasic adenosarcoma-like structure...
  44. Giacalone P, El Gareh N, Haddad O, Bonnier P, Laffargue F. [Evaluation and treatment of endometrial cancer]. Rev Prat. 2001;51:1444-8 pubmed
    ..When necessary, subsequent treatment uses irradiation. Treatment with hormones or antimitotic drugs is less effective and is used for forms that are locally advanced, metastatic or recurrent after initial treatment. ..
  45. Schrecengost A. Ovarian mass--benign or malignant?. AORN J. 2002;76:792-802, 805-6; quiz 807-10 pubmed
    ..This article discusses the epidemiology of ovarian cancer, the components of diagnostic screening, and treatment options. Nursing care of the patient undergoing surgical treatment for ovarian cancer also is discussed. ..
  46. Venkatraman L, Elliott H, Steele E, McClelland H, McCluggage W. Serous carcinoma arising in an adenofibroma of the endometrium. Int J Gynecol Pathol. 2003;22:194-7 pubmed
    ..The carcinoma involved the myometrium and cervix (stage IIa). To our knowledge, this is the third documented case of an adenocarcinoma and the first serous carcinoma involving a uterine adenofibroma. ..
  47. Soslow R. Mixed Müllerian Tumors of the Female Genital Tract. Surg Pathol Clin. 2009;2:707-30 pubmed publisher
    Malignant mixed müllerian tumor (MMMT) and müllerian/mesodermal adenosarcoma are 2 of the most common mixed müllerian tumors of the female genital tract...
  48. Arenas M, Rovirosa A, Hernandez V, Ordi J, Jorcano S, Mellado B, et al. Uterine sarcomas in breast cancer patients treated with tamoxifen. Int J Gynecol Cancer. 2006;16:861-5 pubmed
    ..Two patients had a carcinosarcoma and one patient had an adenosarcoma. After treatment, the disease progressed in two patients and the third patient is alive having a follow-up of ..
  49. Lee J, Lu T, Changou C, Liang C, Huang H, Lauria A, et al. Genomewide copy number analysis of Müllerian adenosarcoma identified chromosomal instability in the aggressive subgroup. Mod Pathol. 2016;29:1070-82 pubmed publisher
    ..To our knowledge, this is the first time that evidence of chromothripsis has been demonstrated in paraffin-embedded clinical tissues and in adenosarcomas. ..
  50. Garalejić E, Arsic B, Perovic M, Vasiljevic M, Usaj S, Stanojevic D. Adenosarcoma ovarii in a 51-year-old woman: case report. Eur J Gynaecol Oncol. 2012;33:543-5 pubmed
    This case report presents a 51-year-old woman with an adenosarcoma of ovarian origin which is a very rare tumor. She came for consultation due to abnormal vaginal bleeding...
  51. Achcar R, Nikiforova M, Dacic S, Nicholson A, Yousem S. Mammalian mastermind like 2 11q21 gene rearrangement in bronchopulmonary mucoepidermoid carcinoma. Hum Pathol. 2009;40:854-60 pubmed publisher
  52. Tanner E, Toussaint T, Leitao M, Hensley M, Soslow R, Gardner G, et al. Management of uterine adenosarcomas with and without sarcomatous overgrowth. Gynecol Oncol. 2013;129:140-4 pubmed publisher
    ..We sought to evaluate the role of primary surgery, adjuvant treatments, and salvage therapies for patients with uterine adenosarcomas...
  53. Español A, Sales M. Different muscarinc receptors are involved in the proliferation of murine mammary adenocarcinoma cell lines. Int J Mol Med. 2004;13:311-7 pubmed
    ..CARB-induced LM2 cells proliferation needed both M2 and M1 receptor activation, promoting prostaglandin E2 liberation and arginase catabolism respectively, both of them involved in tumor cell growth...
  54. Hirakawa E, Yamamoto Y, Fujimoto C, Kobayashi S, Haba R, Ishikawa M, et al. Aggressive adenosarcoma of the ovary. Histopathology. 2003;42:202-3 pubmed
  55. Bagga R, Keepanasseril A, Srinivasan R, Dey P, Gainder S, Saha S, et al. Adenosarcoma of the uterine cervix with heterologous elements: a case report and review of literature. Arch Gynecol Obstet. 2010;281:669-75 pubmed publisher
    b>Adenosarcoma of the uterus is a rare tumor composed of benign epithelial and malignant stromal components, usually encountered in young women...
  56. Mohammadizadeh F, Rajabi P, Behnamfar F, Hani M, Bagheri M. Extensive Overgrowth of Sex Cord-Like Differentiation in Uterine Mullerian Adenosarcoma: A Rare and Challenging Entity. Int J Gynecol Pathol. 2016;35:153-61 pubmed publisher
    ..Sex cord differentiation has been rarely observed in uterine mullerian adenosarcoma. Only 3 cases of such occurrence have been reported in the English literature...
  57. Bernard B, Clarke B, Malowany J, McAlpine J, Lee C, Atenafu E, et al. Uterine adenosarcomas: a dual-institution update on staging, prognosis and survival. Gynecol Oncol. 2013;131:634-9 pubmed publisher
    ..Uterine adenosarcomas (AS) are rare tumors thought to have a favorable prognosis. The aim of this study was to evaluate clinicopathological characteristics and treatment outcome in women with uterine AS...
  58. Nagai Y, Kishimoto T, Kato K, Ozaki D, Kondo F, Kobayashi A, et al. Uterine adenosarcoma with sarcomatous overgrowth: a case report with cytology of overgrown poorly differentiated sarcoma and immunohistochemical identification of epithelial microinvasion. Int J Gynecol Cancer. 2002;12:501-5 pubmed
    In this report, we describe a case of adenosarcoma of the uterine corpus with overgrown and poorly differentiated sarcoma. The patient was an 80-year-old Japanese woman with abnormal genital bleeding...
  59. Mhawech P, Vlastos A, Pelte M. Pathologic quiz case. Uterine polypoid mass in a postmenopausal patient following tamoxifen treatment for breast cancer. Arch Pathol Lab Med. 2002;126:1125-6 pubmed
  60. Meguro S, Yasuda M, Shimizu M, Kurosaki A, Fujiwara K. Mesonephric adenocarcinoma with a sarcomatous component, a notable subtype of cervical carcinosarcoma: a case report and review of the literature. Diagn Pathol. 2013;8:74 pubmed publisher
    ..We think the presence of a sarcomatous component in the cervical biopsy specimen could be helpful in the diagnosis of mesonephric duct origin. ..
  61. Elshafie M, Rahimi S, Ganesan R, Hirschowitz L. Müllerian adenosarcoma arising in a subserosal adenomyoma. Int J Surg Pathol. 2013;21:186-9 pubmed publisher
    ..The authors report a rare case of extraendometrial, intramural adenosarcoma of low grade arising from a subserosal adenomyoma in a 46-year-old woman who presented with vaginal bleeding...
  62. Takeshima N, Tabata T, Nishida H, Arai Y, Tsuzuku M, Hirai Y, et al. Müllerian adenosarcoma of the uterus: report of a case with imprint cytology. Acta Cytol. 2001;45:613-6 pubmed
    Müllerian adenosarcoma is a rare morphologic variant of uterine sarcoma that, although well described histologically, is scarcely mentioned in the cytologic literature.
  63. Arend R, Bagaria M, Lewin S, Sun X, Deutsch I, Burke W, et al. Long-term outcome and natural history of uterine adenosarcomas. Gynecol Oncol. 2010;119:305-8 pubmed publisher
    ..We examined the natural history of uterine adenosarcomas and compared the outcome of uterine adenosarcoma and carcinosarcoma.
  64. Tai L, Tavassoli F. Endometrial polyps with atypical (bizarre) stromal cells. Am J Surg Pathol. 2002;26:505-9 pubmed
    ..The differential diagnoses included adenosarcoma, endometrial stromal sarcoma, and, less likely, malignant mesodermal mixed tumor (MMMT/carcinosarcoma)...
  65. Farah I, Begum R. Effect of Nigella sativa (N. sativa L.) and oxidative stress on the survival pattern of MCF-7 breast cancer cells. Biomed Sci Instrum. 2003;39:359-64 pubmed
    ..Sativa alone or in combination with oxidative stress were found to be effective in vitro in inactivating MCF-7 breast cancer cells, unveiling opportunities for promising results in the field of prevention and treatment of cancer...
  66. Potters L, Calguaru E, Thornton K, Jackson T, Huang D. Toward a dynamic real-time intraoperative permanent prostate brachytherapy methodology. Brachytherapy. 2003;2:172-80 pubmed
    ..To evaluate dosimetry and source location relative to CT-based dosimetry when performing real-time dynamic permanent prostate brachytherapy (PPB) with inverse treatment planning...
  67. Raffaelli R, Piazzola E, Zanconato G, Fedele L. A rare case of extrauterine adenosarcoma arising in endometriosis of the rectovaginal septum. Fertil Steril. 2004;81:1142-4 pubmed
    ..To present a rare case of endometrial stromal sarcoma arising in endometriosis of the rectovaginal septum...
  68. Gonzalez Bosquet E, Sunol M, Callejo J, Lailla J. Uterine adenosarcoma diagnosed following hysteroscopic resection of an intrauterine tumour. Eur J Gynaecol Oncol. 2005;26:415-7 pubmed
    Uterine adenosarcoma is a mixed müllerian tumour consisting of a benign epithelial component and a malignant stromal component. It is a rare tumour that represents 8% of uterine sarcomas...
  69. Tse K, Crawford R, Ngan H. Staging of uterine sarcomas. Best Pract Res Clin Obstet Gynaecol. 2011;25:733-49 pubmed publisher
    Uterine sarcomas comprise leiomyosarcoma, endometrial stromal sarcoma, adenosarcoma, undifferentiated endometrial sarcoma, and their variants...
  70. Matsumoto Y, Ishiko O, Sumi T, Yoshida H, Deguchi M, Nakagawa E, et al. Cyclooxygenase-2 expression in malignant mesenchymal tumors and related uterine lesions. Oncol Rep. 2001;8:1225-7 pubmed
    ..Nineteen sections of tissues from uterine sarcomas, carcinosarcomas, and an adenosarcoma, and endometrial stromal sarcomas, were immunohistochemically analyzed for the cellular expression of COX-2...
  71. Stolnicu S, Balachandran K, Aleykutty M, Loghin A, Preda O, Goez E, et al. Uterine adenosarcomas overgrown by sex-cord-like tumour: report of two cases. J Clin Pathol. 2009;62:942-4 pubmed publisher
    ..Quantitative assessment of volume percentage of the potentially aggressive LGESS, CD10+ areas should be considered as a relevant prognostic histological parameter in these tumours...
  72. Schroeder B, Rodler E, Loggers E, Pollack S, Jones R. Clinical benefit of trabectedin in uterine adenosarcoma. Med Oncol. 2013;30:501 pubmed publisher
    Uterine adenosarcoma is an extremely rare uterine malignancy, and the utility of chemotherapy in this disease is not well defined...
  73. Guo D, Pang S, Shen Y. [Atypical endometriosis: a clinicopathologic study of 163 cases]. Zhonghua Fu Chan Ke Za Zhi. 2008;43:831-4 pubmed
    ..To investigate the clinicopathologic features of atypical endometriosis (AEM) and to discuss the relationship between AEM and tumors...
  74. Litta P, Pozzan C, Sacco G, Merlin F, Saccardi C, Ambrosini A. Adenosarcoma of the ovary. A case report. Eur J Gynaecol Oncol. 2004;25:507-8 pubmed
    b>Adenosarcoma of the ovary is a rare condition. We report a case of a 32-year-old patient that has been treated in our Department...
  75. Crade M, Weber P. Pedicle sign and diagnosis of endometrial adenosarcoma. J Ultrasound Med. 2004;23:1217-9 pubmed
  76. Amant F, Vloeberghs V, Woestenborghs H, Debiec Rychter M, Verbist L, Moerman P, et al. ERBB-2 gene overexpression and amplification in uterine sarcomas. Gynecol Oncol. 2004;95:583-7 pubmed
    ..The aim of this study was to determine ERBB-2 (HER-2/neu) gene alterations in different subtypes of uterine sarcomas...
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    Müllerian adenosarcoma harbors low malignant potential, except in cases with myometrial invasion or sarcomatous overgrowth. The presence of a high-grade stromal component has been proposed as an important pathologic predictor of outcome...