skull base neoplasms

Summary

Summary: Neoplasms of the base of the skull specifically, differentiated from neoplasms of unspecified sites or bones of the skull (SKULL NEOPLASMS).

Top Publications

  1. Casali P, Stacchiotti S, Sangalli C, Olmi P, Gronchi A. Chordoma. Curr Opin Oncol. 2007;19:367-70 pubmed
    ..To review developments in chordoma treatment...
  2. Ramina R, Neto M, Fernandes Y, Silva E, Mattei T, Aguiar P. Surgical removal of small petroclival meningiomas. Acta Neurochir (Wien). 2008;150:431-8; discussion 438-9 pubmed publisher
    ..8 cm) treated with radical surgical removal. Total resection (Simpson's Grade 1) [43] was possible with minimal morbidity and no mortality...
  3. Starke R, Williams B, Hiles C, Nguyen J, Elsharkawy M, Sheehan J. Gamma knife surgery for skull base meningiomas. J Neurosurg. 2012;116:588-97 pubmed publisher
    ..In this study, the authors evaluate the outcomes of skull base meningiomas treated with Gamma Knife surgery (GKS) both as an adjunct to microsurgery and as a primary treatment modality...
  4. Minniti G, Clarke E, Cavallo L, Osti M, Esposito V, Cantore G, et al. Fractionated stereotactic conformal radiotherapy for large benign skull base meningiomas. Radiat Oncol. 2011;6:36 pubmed publisher
    ..To assess the safety and efficacy of fractionated stereotactic radiotherapy (FSRT) for large skull base meningiomas...
  5. Patel A, Rao V, Fox B, Suki D, Wildrick D, Sawaya R, et al. Radiation-induced osteosarcomas of the calvarium and skull base. Cancer. 2011;117:2120-6 pubmed publisher
    ..To date, publications on radiation-induced osteosarcoma of the cranium are limited to a few small series and case reports...
  6. Di Maio S, Temkin N, Ramanathan D, Sekhar L. Current comprehensive management of cranial base chordomas: 10-year meta-analysis of observational studies. J Neurosurg. 2011;115:1094-105 pubmed publisher
    ..This meta-analysis measures the relationship of complete resection and type of adjuvant radiation therapy to 5-year progression-free survival (PFS) and overall survival (OS) of cranial base chordomas...
  7. Komotar R, Starke R, Raper D, Anand V, Schwartz T. The endoscope-assisted ventral approach compared with open microscope-assisted surgery for clival chordomas. World Neurosurg. 2011;76:318-27; discussion 259-62 pubmed publisher
    ..We conducted a systematic review of case series and case reports in hope of furthering our understanding of the role of endoscopy in the management of these difficult cranial base lesions...
  8. Komotar R, Starke R, Raper D, Anand V, Schwartz T. Endoscopic endonasal versus open transcranial resection of anterior midline skull base meningiomas. World Neurosurg. 2012;77:713-24 pubmed publisher
  9. Astner S, Dobrei Ciuchendea M, Essler M, Bundschuh R, Sai H, Schwaiger M, et al. Effect of 11C-methionine-positron emission tomography on gross tumor volume delineation in stereotactic radiotherapy of skull base meningiomas. Int J Radiat Oncol Biol Phys. 2008;72:1161-7 pubmed publisher

More Information

Publications62

  1. Deinsberger R, Tidstrand J, Sabitzer H, Lanner G. LINAC radiosurgery in skull base meningiomas. Minim Invasive Neurosurg. 2004;47:333-8 pubmed
    ..By combining microsurgery and radiosurgery we can achieve high tumor control rates with an acceptable low morbidity and a high level of quality of life...
  2. Fayad J, Keles B, Brackmann D. Jugular foramen tumors: clinical characteristics and treatment outcomes. Otol Neurotol. 2010;31:299-305 pubmed publisher
    ..To describe the diagnosis, management, and treatment outcome of jugular foramen (JF) tumors...
  3. Liu J, Sameshima T, Gottfried O, Couldwell W, Fukushima T. The combined transmastoid retro- and infralabyrinthine transjugular transcondylar transtubercular high cervical approach for resection of glomus jugulare tumors. Neurosurgery. 2006;59:ONS115-25; discussion ONS115-25 pubmed
    ..The details of this approach are described and illustrated in a stepwise fashion, and the microsurgical anatomy is reviewed...
  4. Seifert V. Clinical management of petroclival meningiomas and the eternal quest for preservation of quality of life: personal experiences over a period of 20 years. Acta Neurochir (Wien). 2010;152:1099-116 pubmed publisher
    ..Surgical concepts and the operative decision-making process are demonstrated in four illustrative cases...
  5. Sade B, Chahlavi A, Krishnaney A, Nagel S, Choi E, Lee J. World Health Organization Grades II and III meningiomas are rare in the cranial base and spine. Neurosurgery. 2007;61:1194-8; discussion 1198 pubmed
    ..This study was undertaken to assess a possible relationship between the tumor location and the incidence of World Health Organization (WHO) Grades II and III meningiomas...
  6. Han J, Kim D, Chung H, Park C, Paek S, Kim C, et al. Gamma knife radiosurgery for skull base meningiomas: long-term radiologic and clinical outcome. Int J Radiat Oncol Biol Phys. 2008;72:1324-32 pubmed publisher
    ..To analyze the long-term outcomes in patients with skull base meningiomas (SBMNGs) treated with Gamma Knife radiosurgery (GKRS)...
  7. Hasegawa T, Ishii D, Kida Y, Yoshimoto M, Koike J, Iizuka H. Gamma Knife surgery for skull base chordomas and chondrosarcomas. J Neurosurg. 2007;107:752-7 pubmed
    ..The purpose of this study was to evaluate radiosurgical outcomes in skull base chordomas and chondrosarcomas, and to determine which tumors are appropriate for stereotactic radiosurgery as adjuvant therapy following maximum tumor resection...
  8. Durden D, Williams D. Radiology of skull base neoplasms. Otolaryngol Clin North Am. 2001;34:1043-64, vii pubmed
    Computed tomography (CT) and magnetic resonance (MR) imaging are used routinely to stage skull base neoplasms preoperatively, define the extent of the tumor, identify perineural spread, plan surgery and radiation therapy, and evaluate the ..
  9. Rutten I, Cabay J, Withofs N, Lemaire C, Aerts J, Baart V, et al. PET/CT of skull base meningiomas using 2-18F-fluoro-L-tyrosine: initial report. J Nucl Med. 2007;48:720-5 pubmed
    ..We report our results with PET/CT and 2-(18)F-fluoro-L-tyrosine ((18)F-TYR), a marker of amino acid transport, as part of the yearly follow-up of irradiated patients...
  10. Schlampp I, Karger C, Jäkel O, Scholz M, Didinger B, Nikoghosyan A, et al. Temporal lobe reactions after radiotherapy with carbon ions: incidence and estimation of the relative biological effectiveness by the local effect model. Int J Radiat Oncol Biol Phys. 2011;80:815-23 pubmed publisher
  11. Baumert B, Norton I, Davis J. Intensity-modulated stereotactic radiotherapy vs. stereotactic conformal radiotherapy for the treatment of meningioma located predominantly in the skull base. Int J Radiat Oncol Biol Phys. 2003;57:580-92 pubmed
    ..This study evaluates a possible advantage of intensity-modulated stereotactic radiotherapy (IMSRT) over stereotactic conformal radiotherapy (SCRT) in the treatment of lesions in the base of the skull...
  12. Schick U, Hassler W. Surgical management of tuberculum sellae meningiomas: involvement of the optic canal and visual outcome. J Neurol Neurosurg Psychiatry. 2005;76:977-83 pubmed
    ..To present a large series of surgically treated tuberculum sellae meningiomas with particular regard to involvement of the optic canal and visual outcome...
  13. Kreil W, Luggin J, Fuchs I, Weigl V, Eustacchio S, Papaefthymiou G. Long term experience of gamma knife radiosurgery for benign skull base meningiomas. J Neurol Neurosurg Psychiatry. 2005;76:1425-30 pubmed
  14. Wong E, Lu X, Devulapalli J, Mahadevan A. Cyberknife radiosurgery for basal skull plasmacytoma. J Neuroimaging. 2006;16:361-3 pubmed
    ..To our knowledge, this is a first case of successful Cyberknife radiosurgery of a medullary plasmacytoma...
  15. Schulz Ertner D, Tsujii H. Particle radiation therapy using proton and heavier ion beams. J Clin Oncol. 2007;25:953-64 pubmed
    ..Clinical trials investigating proton and carbon ion RT will be summarized and discussed in the context of their relevance to recent concepts of treatment with RT...
  16. Bindal R, Goodman J, Kawasaki A, Purvin V, Kuzma B. The natural history of untreated skull base meningiomas. Surg Neurol. 2003;59:87-92; discussion 92 pubmed
    ..Although there are reports on the natural history of meningiomas, most series contain only a few cases of meningiomas involving the skull base. Natural history information is important when recommending treatment and evaluating results...
  17. Amichetti M, Cianchetti M, Amelio D, Enrici R, Minniti G. Proton therapy in chordoma of the base of the skull: a systematic review. Neurosurg Rev. 2009;32:403-16 pubmed publisher
  18. Conley G, Hirsch B. Stereotactic radiation treatment of vestibular schwannoma: indications, limitations, and outcomes. Curr Opin Otolaryngol Head Neck Surg. 2010;18:351-6 pubmed publisher
    ..The recent literature regarding the indications, limitations, and outcomes for stereotactic radiation treatment is reviewed...
  19. Mendenhall W, Morris C, Amdur R, Foote K, Friedman W. Radiotherapy alone or after subtotal resection for benign skull base meningiomas. Cancer. 2003;98:1473-82 pubmed
    ..The objective of the current study was to analyze the long-term local control and complications in a series of patients who were treated with radiotherapy for benign skull base meningiomas...
  20. Adler J, Gibbs I, Puataweepong P, Chang S. Visual field preservation after multisession cyberknife radiosurgery for perioptic lesions. Neurosurgery. 2006;59:244-54; discussion 244-54 pubmed
    ..The current retrospective study is intended to help address these shortcomings...
  21. Nicolai P, Battaglia P, Bignami M, Bolzoni Villaret A, Delù G, Khrais T, et al. Endoscopic surgery for malignant tumors of the sinonasal tract and adjacent skull base: a 10-year experience. Am J Rhinol. 2008;22:308-16 pubmed publisher
    ..We report our experience with the endoscopic management of nasoethmoidal malignancies possibly involving the adjacent skull base...
  22. Mathiesen T, Kihlström L. Visual outcome of tuberculum sellae meningiomas after extradural optic nerve decompression. Neurosurgery. 2006;59:570-6; discussion 570-6 pubmed
  23. Kondziolka D, Flickinger J, Lunsford L. The principles of skull base radiosurgery. Neurosurg Focus. 2008;24:E11 pubmed publisher
    ..In this report, the authors discuss technical concepts and dose selection in skull base radiosurgery...
  24. Noel G, Feuvret L, Calugaru V, Dhermain F, Mammar H, Haie Meder C, et al. Chordomas of the base of the skull and upper cervical spine. One hundred patients irradiated by a 3D conformal technique combining photon and proton beams. Acta Oncol. 2005;44:700-8 pubmed
    ..The role of surgical resection remains paramount, and a trial of dose escalation would have to consider an increase in the dose to critical organs, especially as current results indicate the low toxicity of this treatment...
  25. Weber D, Rutz H, Pedroni E, Bolsi A, Timmermann B, Verwey J, et al. Results of spot-scanning proton radiation therapy for chordoma and chondrosarcoma of the skull base: the Paul Scherrer Institut experience. Int J Radiat Oncol Biol Phys. 2005;63:401-9 pubmed
    ..To assess the clinical results of spot scanning proton beam radiation therapy (PT) in the treatment of skull base chordomas and low-grade chondrosarcomas (CS)...
  26. Ito E, Saito K, Okada T, Nagatani T, Nagasaka T. Long-term control of clival chordoma with initial aggressive surgical resection and gamma knife radiosurgery for recurrence. Acta Neurochir (Wien). 2010;152:57-67; discussion 67 pubmed publisher
    ..This study analyzed long-term outcomes for clival chordomas after initial aggressive surgical resection and gamma knife radiosurgery for recurrence and investigated clinical factors predicting recurrence...
  27. Chang S, Martin D, Lee E, Adler J. Stereotactic radiosurgery and hypofractionated stereotactic radiotherapy for residual or recurrent cranial base and cervical chordomas. Neurosurg Focus. 2001;10:E5 pubmed
    ..The authors review their experience in using linear accelerator (LINAC) stereotactic radiosurgery to treat patients with recurrent and/or residual cranial base and cervical chordomas...
  28. Cho Y, Kim J, Khang S, Lee J, Kim C. Chordomas and chondrosarcomas of the skull base: comparative analysis of clinical results in 30 patients. Neurosurg Rev. 2008;31:35-43; discussion 43 pubmed
    ..As the biological behavior of chordoma is much more aggressive than that of chondrosarcoma in the skull base, one should make a distinction between these entities to plan an optimal treatment strategy...
  29. Amichetti M, Amelio D, Cianchetti M, Enrici R, Minniti G. A systematic review of proton therapy in the treatment of chondrosarcoma of the skull base. Neurosurg Rev. 2010;33:155-65 pubmed publisher
    ..The use of PT following maximal surgical resection shows a very high probability of medium- and long-term cure with a relatively low risk of significant complications...
  30. Minniti G, Valeriani M, Clarke E, D Arienzo M, Ciotti M, Montagnoli R, et al. Fractionated stereotactic radiotherapy for skull base tumors: analysis of treatment accuracy using a stereotactic mask fixation system. Radiat Oncol. 2010;5:1 pubmed publisher
    ..To assess the accuracy of fractionated stereotactic radiotherapy (FSRT) using a stereotactic mask fixation system...
  31. Sughrue M, Kane A, Shangari G, Rutkowski M, McDermott M, Berger M, et al. The relevance of Simpson Grade I and II resection in modern neurosurgical treatment of World Health Organization Grade I meningiomas. J Neurosurg. 2010;113:1029-35 pubmed publisher
  32. Starke R, Nguyen J, Rainey J, Williams B, Sherman J, Savage J, et al. Gamma Knife surgery of meningiomas located in the posterior fossa: factors predictive of outcome and remission. J Neurosurg. 2011;114:1399-409 pubmed publisher
    ..In this study, the authors evaluate the outcomes of posterior fossa meningiomas treated with Gamma Knife surgery (GKS). The authors also assess factors predictive of new postoperative neurological deficits and tumor progression...
  33. Nakaya K, Niranjan A, Kondziolka D, Kano H, Khan A, Nettel B, et al. Gamma knife radiosurgery for benign tumors with symptoms from brainstem compression. Int J Radiat Oncol Biol Phys. 2010;77:988-95 pubmed publisher
    ..This study evaluated the role of radiosurgery in the management of symptomatic patients with brainstem compression from benign basal tumors...
  34. Eustacchio S, Trummer M, Fuchs I, Schröttner O, Sutter B, Pendl G. Preservation of cranial nerve function following Gamma Knife radiosurgery for benign skull base meningiomas: experience in 121 patients with follow-up of 5 to 9.8 years. Acta Neurochir Suppl. 2002;84:71-6 pubmed
    ..In this study we evaluated the effect of Gamma Knife Radiosurgery (GKRS) in 121 patients with benign basal meningiomas after a follow-up of 5 to 9.8 years...
  35. Otani N, Muroi C, Yano H, Khan N, Pangalu A, Yonekawa Y. Surgical management of tuberculum sellae meningioma: role of selective extradural anterior clinoidectomy. Br J Neurosurg. 2006;20:129-38 pubmed
  36. Colli B, Al Mefty O. Chordomas of the skull base: follow-up review and prognostic factors. Neurosurg Focus. 2001;10:E1 pubmed
    ..The authors analyze the data and prognostic factors obtained during the follow-up period (range 1-150 months, median 38 months) in 53 patients with craniocervical junction chordoma and 10 patients with chondrosarcoma...
  37. Jalali R, Loughrey C, Baumert B, Perks J, Warrington A, Traish D, et al. High precision focused irradiation in the form of fractionated stereotactic conformal radiotherapy (SCRT) for benign meningiomas predominantly in the skull base location. Clin Oncol (R Coll Radiol). 2002;14:103-9 pubmed
    ..To present early clinical results of stereotactic conformal radiotherapy (SCRT) in patients with benign predominantly skull base meningiomas...
  38. Steinvorth S, Welzel G, Fuss M, Debus J, Wildermuth S, Wannenmacher M, et al. Neuropsychological outcome after fractionated stereotactic radiotherapy (FSRT) for base of skull meningiomas: a prospective 1-year follow-up. Radiother Oncol. 2003;69:177-82 pubmed
    ..The purpose of this study was to evaluate the cognitive outcome after fractionated stereotactic radiotherapy (FSRT) in patients with base of skull meningiomas...
  39. Mendenhall W, Mendenhall C, Lewis S, Villaret D, Mendenhall N. Skull base chordoma. Head Neck. 2005;27:159-65 pubmed
    ..Our purpose was to discuss the optimal treatment and outcomes for patients with skull base chordomas...
  40. Metellus P, Regis J, Muracciole X, Fuentes S, Dufour H, Nanni I, et al. Evaluation of fractionated radiotherapy and gamma knife radiosurgery in cavernous sinus meningiomas: treatment strategy. Neurosurgery. 2005;57:873-86; discussion 873-86 pubmed
    ..To investigate the respective role of fractionated radiotherapy (FR) and gamma knife stereotactic (GKS) radiosurgery in cavernous sinus meningioma (CSM) treatment...
  41. Jambhekar N, Rekhi B, Thorat K, Dikshit R, Agrawal M, Puri A. Revisiting chordoma with brachyury, a "new age" marker: analysis of a validation study on 51 cases. Arch Pathol Lab Med. 2010;134:1181-7 pubmed publisher
    ..At times, it presents a diagnostic challenge, especially in small biopsies. Brachyury, a nuclear transcription factor, is a recently described immunohistochemical marker for diagnosing chordomas...
  42. Lanzino G, Dumont A, Lopes M, Laws E. Skull base chordomas: overview of disease, management options, and outcome. Neurosurg Focus. 2001;10:E12 pubmed
    ..Recurrences are common, although in a subset of patients prolonged disease-free survival is demonstrated...
  43. Samii A, Gerganov V, Herold C, Hayashi N, Naka T, Mirzayan M, et al. Chordomas of the skull base: surgical management and outcome. J Neurosurg. 2007;107:319-24 pubmed
    ..The goal of this study was to report on the surgical management of skull base chordomas and to evaluate both the short- and long-term treatment outcomes...
  44. Martin J, Niranjan A, Kondziolka D, Flickinger J, Lozanne K, Lunsford L. Radiosurgery for chordomas and chondrosarcomas of the skull base. J Neurosurg. 2007;107:758-64 pubmed
    ..The authors evaluated the effect of stereotactic radiosurgery (SRS) on local tumor control and survival...
  45. Berkmann S, Tolnay M, Hänggi D, Ghaffari A, Gratzl O. Sarcoma of the sella after radiotherapy for pituitary adenoma. Acta Neurochir (Wien). 2010;152:1725-35 pubmed publisher
    ..Additionally, one must include these tumors into the differential diagnosis in pituitary patients presenting with tumor recurrence more than 5 years after radiotherapy in combination with a secondary lack of hormonal activity...
  46. Takanashi M, Fukuoka S, Hojyo A, Sasaki T, Nakagawara J, Nakamura H. Gamma knife radiosurgery for skull-base meningiomas. Prog Neurol Surg. 2009;22:96-111 pubmed publisher
  47. Zachenhofer I, Wolfsberger S, Aichholzer M, Bertalanffy A, Roessler K, Kitz K, et al. Gamma-knife radiosurgery for cranial base meningiomas: experience of tumor control, clinical course, and morbidity in a follow-up of more than 8 years. Neurosurgery. 2006;58:28-36; discussion 28-36 pubmed
    ..However, reports of long-term results are still sparse. We therefore performed this study to analyze the long-term results of GKRS treatment of cranial base meningiomas, following our previously published early follow-up experience...
  48. Schulz Ertner D, Karger C, Feuerhake A, Nikoghosyan A, Combs S, Jäkel O, et al. Effectiveness of carbon ion radiotherapy in the treatment of skull-base chordomas. Int J Radiat Oncol Biol Phys. 2007;68:449-57 pubmed
    ..The aim of this study was to evaluate the effectiveness and toxicity of carbon ion radiotherapy in chordomas of the skull base...
  49. Witt T, Lo S, Timmerman R. Successful treatment of a skull base malignant rhabdoid tumor with surgery, chemotherapy and gamma Knife-based stereotactic radiosurgery in a young child. Stereotact Funct Neurosurg. 2007;85:310-3 pubmed
    ..There were no obvious endocrine deficits or growth abnormalities at last follow-up. Gamma Knife-based stereotactic radiosurgery may have a role in the management of very young children with skull base tumors...
  50. Pollock B, Foote R. The evolving role of stereotactic radiosurgery for patients with skull base tumors. J Neurooncol. 2004;69:199-207 pubmed
    ..Follow-up beyond 10 years is still needed to better define long-term results of radiosurgery and the incidence of radiation-induced neoplasms after radiosurgery...
  51. Lee N, Millender L, Larson D, Wara W, McDermott M, Kaplan M, et al. Gamma knife radiosurgery for recurrent salivary gland malignancies involving the base of skull. Head Neck. 2003;25:210-6 pubmed
    ..The management of skull base recurrence of salivary gland tumors is challenging, because complete surgical resection and fractionated reirradiation are seldom possible. Experience is being gained with radiosurgery for this indication...
  52. Davidson L, Fishback D, Russin J, Weiss M, Yu C, Pagnini P, et al. Postoperative Gamma Knife surgery for benign meningiomas of the cranial base. Neurosurg Focus. 2007;23:E6 pubmed
    ..The authors analyzed the mid- and long-term results obtained in patients treated with postresection Gamma Knife surgery (GKS) for residual or recurrent benign meningiomas of the cranial base...
  53. Hamm K, Henzel M, Gross M, Surber G, Kleinert G, Engenhart Cabillic R. Radiosurgery/stereotactic radiotherapy in the therapeutical concept for skull base meningiomas. Zentralbl Neurochir. 2008;69:14-21 pubmed publisher
    ..Stereotactically guided radiation therapy - radiosurgery (RS) or stereotactic radiotherapy (SRT) - offers an additional or alternate treatment option for those patients. We evaluated local control rates, symptomatology, and toxicity...