femoral neoplasms

Summary

Summary: New abnormal growth of tissue in the FEMUR.

Top Publications

  1. Menendez L, Ahlmann E, Kermani C, Gotha H. Endoprosthetic reconstruction for neoplasms of the proximal femur. Clin Orthop Relat Res. 2006;450:46-51 pubmed
    ..Bipolar head segments should be used whenever possible because of increased survival and decreased rates of dislocation...
  2. Hierholzer J, Anselmetti G, Fuchs H, Depriester C, Koch K, Pappert D. Percutaneous osteoplasty as a treatment for painful malignant bone lesions of the pelvis and femur. J Vasc Interv Radiol. 2003;14:773-7 pubmed
    ..The immediate good clinical results observed in our small patient group should encourage more widespread application of this palliative treatment...
  3. Matsumine A, Ueda T, Sugita T, Yazawa Y, Isu K, Kawai A, et al. Clinical outcomes of the KYOCERA Physio Hinge Total Knee System Type III after the resection of a bone and soft tissue tumor of the distal part of the femur. J Surg Oncol. 2011;103:257-63 pubmed publisher
    ..The clinical outcomes of the PHKIII after the resection of musculoskeletal tumors of the distal femur were evaluated...
  4. Biau D, Davis A, Vastel L, Tomeno B, Anract P. Function, disability, and health-related quality of life after allograft-prosthesis composite reconstructions of the proximal femur. J Surg Oncol. 2008;97:210-5 pubmed
    ..Factors affecting function, disability and health-related quality of life after allograft-prosthesis composite reconstructions have been poorly studied...
  5. Finstein J, King J, Fox E, Ogilvie C, Lackman R. Bipolar proximal femoral replacement prostheses for musculoskeletal neoplasms. Clin Orthop Relat Res. 2007;459:66-75 pubmed
    ..Bipolar PFRPs have good long-term durability with some complications, but are able to preserve the limb and provide good function for patients...
  6. Avedian R, Goldsby R, Kramer M, O Donnell R. Effect of chemotherapy on initial compressive osseointegration of tumor endoprostheses. Clin Orthop Relat Res. 2007;459:48-53 pubmed
    ..These findings have important implications for the patients with musculoskeletal tumors...
  7. Myers G, Abudu A, Carter S, Tillman R, Grimer R. Endoprosthetic replacement of the distal femur for bone tumours: long-term results. J Bone Joint Surg Br. 2007;89:521-6 pubmed
    ..We believe that a cemented, rotating-hinge prosthesis with a hydroxyapatite collar offers the best chance of long-term survival of the prosthesis...
  8. Morgan H, Cizik A, Leopold S, Hawkins D, Conrad E. Survival of tumor megaprostheses replacements about the knee. Clin Orthop Relat Res. 2006;450:39-45 pubmed
    ..Aseptic loosening was the most common reason for failure (n = 18/32; 56%). The incidence of failure in tumor megaprostheses is similar to early published literature and the incidence of these failures is highest within the first 3 years...
  9. Pedtke A, Wustrack R, Fang A, Grimer R, O Donnell R. Aseptic failure: how does the Compress(®) implant compare to cemented stems?. Clin Orthop Relat Res. 2012;470:735-42 pubmed publisher
    ..Though the existing literature suggests survivorship of Compress(®) and stemmed implants is similar in the short term, studies are limited by population size and followup duration...

More Information

Publications62

  1. Bergin P, Noveau J, Jelinek J, Henshaw R. Aseptic loosening rates in distal femoral endoprostheses: does stem size matter?. Clin Orthop Relat Res. 2012;470:743-50 pubmed publisher
    ..Long-term survival of distal femoral endoprosthetic replacements is largely affected by aseptic loosening. It is unclear whether and to what degree surgical technique and component selection influence the risk of loosening...
  2. Wedin R, Bauer H. Surgical treatment of skeletal metastatic lesions of the proximal femur: endoprosthesis or reconstruction nail?. J Bone Joint Surg Br. 2005;87:1653-7 pubmed
    ..07). Endoprosthetic reconstructions are preferable to the use of reconstruction nails and other osteosynthetic devices for the treatment of metastatic lesions in the proximal third of the femur...
  3. Kramer M, Tanner B, Horvai A, O Donnell R. Compressive osseointegration promotes viable bone at the endoprosthetic interface: retrieval study of Compress implants. Int Orthop. 2008;32:567-71 pubmed
    ..No patient demonstrated histological evidence of osteonecrosis. In fact, new woven bone and other findings consistent with viable bone were noted in all of the retrieved specimens...
  4. Yamada K, Matsumoto Y, Kita M, Yamamoto K, Kohda W, Kobayashi T, et al. Clinical outcome of percutaneous osteoplasty for pain caused by metastatic bone tumors in the pelvis and femur. J Anesth. 2007;21:277-81 pubmed
    ..Percutaneous osteoplasty is a safe and effective treatment for pain caused by metastatic bone tumors in the pelvis and femur. However, care and attention should be paid to the risk of pathological fracture after POP of the femur...
  5. Anderson M, Hyodo A, Zehr R, Marks K, Muschler G. Abductor reattachment with a custom proximal femoral replacement prosthesis. Orthopedics. 2002;25:722-6 pubmed
  6. Donati D, Zavatta M, Gozzi E, Giacomini S, Campanacci L, Mercuri M. Modular prosthetic replacement of the proximal femur after resection of a bone tumour a long-term follow-up. J Bone Joint Surg Br. 2001;83:1156-60 pubmed
    ..Functional activity was satisfactory in 68% of the patients. A better system of reattachment of the soft tissues is needed to avoid pain and a persistent limp...
  7. Rompen J, Ham S, Halbertsma J, van Horn J. Gait and function in patients with a femoral endoprosthesis after tumor resection: 18 patients evaluated 12 years after surgery. Acta Orthop Scand. 2002;73:439-46 pubmed
    ..Follow-up studies are needed to evaluate the effects of the asymmetrical gait pattern observed and the abnormal goniometric results on the development of endoprosthesis-related complications...
  8. Agarwala A, Hanna N. Long-term survival in a patient with stage IV non-small-cell lung carcinoma after bone metastasectomy. Clin Lung Cancer. 2005;6:367-8 pubmed
    ..In the rare situation in which a patient has a solitary bone metastasis, aggressive treatment may be warranted, as illustrated by the case reported here...
  9. Weiss R, Ekström W, Hansen B, Keller J, Laitinen M, Trovik C, et al. Pathological subtrochanteric fractures in 194 patients: a comparison of outcome after surgical treatment of pathological and non-pathological fractures. J Surg Oncol. 2013;107:498-504 pubmed publisher
    ..The surgical treatment of pathological subtrochanteric fractures has been associated with technical difficulties and frequent failures. We analyzed survival, risk factors for death, and outcome after surgical treatment...
  10. Gilliaux O, De Wispelaere J, Charlier H, Bodart E. [Osteoid osteoma in children: 5 cases treated with electrocoagulation]. Arch Pediatr. 2012;19:1177-81 pubmed publisher
    ..We reviewed the cases of 5 patients who were hospitalized in our institution for percutaneous electrocoagulation of an osteoid osteoma. We compared them to the literature...
  11. Kreahling J, Foroutan P, Reed D, Martinez G, Razabdouski T, Bui M, et al. Wee1 inhibition by MK-1775 leads to tumor inhibition and enhances efficacy of gemcitabine in human sarcomas. PLoS ONE. 2013;8:e57523 pubmed publisher
    ..Our results together with the high safety profile of MK1775 strongly suggest that this drug can be used as a potential therapeutic agent in the treatment of both adult as well as pediatric sarcoma patients...
  12. Bacci G, Palmerini E, Staals E, Ferrari S, Battaglia M, Longhi A, et al. Spontaneous regression of lung metastasis from osteosarcoma: a case report. J Pediatr Hematol Oncol. 2008;30:90-2 pubmed publisher
    ..The patient was followed up every 3 months and a spontaneous regression of the lesion was documented. Seven years after the diagnosis of lung metastases, no pulmonary nodules or other signs of relapse are present...
  13. Yamamoto Y, Takakuwa Y, Kuroda M, Nakashima H, Washimi Y, Ishimura D, et al. A p53 gene mutation in malignant fibrous histiocytoma associated with bone infarction. Tohoku J Exp Med. 2011;225:215-20 pubmed
    ..Identification of the p53 mutation helps in diagnosing the malignant transformation of the bone infarct lesion. One pathogenesis of this condition may be a mutation in the p53 gene...
  14. Lee S, Yoon J, Bae J, Eun C, Choi J, Suh K, et al. Intracortical lipoma of the femur. Skeletal Radiol. 2007;36 Suppl 1:S77-81 pubmed
    ..Intralesional curettage was performed. Histologically, the tumor consisted of mature, viable adipocytes without foci of fat necrosis or dystrophic calcification...
  15. Simpson A, Ma B, Chen E, Ellis R, Stewart A. Using registration uncertainty visualization in a user study of a simple surgical task. Med Image Comput Comput Assist Interv. 2006;9:397-404 pubmed
    ..Most notably, our work addresses the existence of uncertainty in guidance and offers a first step towards helping surgeons make informed decisions in the presence of imperfect data...
  16. Matsuo T, Sugita T, Shimose S, Kubo T, Sunagawa T, Yasunaga Y, et al. Rigid bridging of massive femur defect using double vascularized fibula graft with hydroxyapatite. Arch Orthop Trauma Surg. 2008;128:941-4 pubmed publisher
    ..Here, a novel surgical procedure for bridging of massive femur defects using double FVFG and hydroxyapatite with autogenous bone grafts to prevent stress fractures is reported...
  17. Marfori M, Wang E. Adductor myocutaneous flap coverage for hip and pelvic disarticulations of sarcomas with buttock contamination. Clin Orthop Relat Res. 2011;469:257-63 pubmed publisher
    ..In cases when neither the conventional posterior gluteus maximus flap nor the anterior quadriceps flap can be used because of the location of the tumor, a medial adductor myocutaneous flap may be an alternative...
  18. Brunet O, Anract P, Bouabid S, Babinet A, Dumaine V, Tomeno B, et al. Intercalary defects reconstruction of the femur and tibia after primary malignant bone tumour resection. A series of 13 cases. Orthop Traumatol Surg Res. 2011;97:512-9 pubmed publisher
    ..The use of an allograft or autograft must ensure long-term survival of the reconstruction. The goal of this study was to analyse the clinical and radiological outcomes of these reconstructions...
  19. Lazar A, Straja N, Bratucu E. An unusual sarcomatous retroperitoneal metastasis. A rare case report with a brief literature review. Chirurgia (Bucur). 2012;107:108-14 pubmed
    ..New tumor markers for the detection and follow-up of these tumors should be considered...
  20. Krauth M, Fodinger M, Rebuzzi L, Greul R, Chott A, Valent P. Aggressive systemic mastocytosis with sarcoma-like growth in the skeleton, leukemic progression, and partial loss of mast cell differentiation antigens. Haematologica. 2007;92:e126-9 pubmed
  21. Cabasson S, Yvert M, Pillet P, Pedespan J. [Neurological manifestations of an osteoid osteoma located on the femoral neck in an 8-year-old boy]. Arch Pediatr. 2012;19:1196-9 pubmed publisher
    ..Deep tendon reflexes are normal, and he only presents residual pain. Physicians should be aware that osteoid osteoma may take the form of a slowly evolving neuropathy. We review the literature on this underestimated condition...
  22. Shinozaki T, Sato J, Watanabe H, Takagishi K, Aoki J, Koyama Y, et al. Osteoid osteoma treated with computed tomography-guided percutaneous radiofrequency ablation: a case series. J Orthop Surg (Hong Kong). 2005;13:317-22 pubmed
    ..This case series shows that the computed tomography-guided percutaneous radiofrequency ablation is a simple, minimally invasive, and highly effective technique for the treatment of osteoid osteoma...
  23. Ahlmann E, Menendez L, Kermani C, Gotha H. Survivorship and clinical outcome of modular endoprosthetic reconstruction for neoplastic disease of the lower limb. J Bone Joint Surg Br. 2006;88:790-5 pubmed
    ..Modular endoprosthetic replacement in the lower limb is a durable long-term reconstructive option, with the implants generally outlasting the patient...
  24. Graziadio M, Medina N, Amato M, Ardaiz M, Ilutovich S, Torino M. [Primary bone lymphoma with multicentric involvement]. Medicina (B Aires). 2012;72:428-30 pubmed
  25. Wang J, Li Y, Liu H, Zhao P. Primary cardiac myxofibrosarcoma: a case report and review of the literature. Tumori. 2012;98:165e-8e pubmed publisher
    ..Primary myxofibrosarcoma of the heart is a rare malignancy. To the best of our knowledge, no more than 17 cases have been reported since 1963...
  26. Gaston C, Bhumbra R, Watanuki M, Abudu A, Carter S, Jeys L, et al. Does the addition of cement improve the rate of local recurrence after curettage of giant cell tumours in bone?. J Bone Joint Surg Br. 2011;93:1665-9 pubmed publisher
    ..001). In patients who developed local recurrence, 75.0% (9 of 12) of those with previous cementation required a joint replacement, compared with 45.2% (33 of 73) of those without cement (p = 0.044)...
  27. Soldado F, Fontecha C, Haddad S, Corona P, Collado D, Llusa M, et al. Composite vascularized fibular epiphyseo-osteo-periosteal transfer for hip reconstruction after proximal femoral tumoral resection in a 4-year-old child. Microsurgery. 2012;32:489-92 pubmed publisher
    ..We also discuss the advantages of designing the flap as a composite vascularized epiphyseo-osteo-periosteal flap...
  28. Iannessi A, Amoretti N, Marcy P, Sedat J. Percutaneous cementoplasty for the treatment of extraspinal painful bone lesion, a prospective study. Diagn Interv Imaging. 2012;93:859-70 pubmed publisher
    ..We prospectively followed 20 patients who received a percutaneous cementoplasty on painful lytic bone lesions between May 2008 and May 2010...
  29. Nagata S, Nishimura H, Uchida M, Hayabuchi N, Zenmyou M, Harada H. Giant cell-rich osteosarcoma of the distal femur: radiographic and magnetic resonance imaging findings. Radiat Med. 2006;24:228-32 pubmed
    ..Giant cell-rich osteosarcomas are sometimes difficult to distinguish from giant cell tumors by age, location, magnetic resonance imaging findings, and pathology. Radiography may be useful in the diagnosis of giant cell-rich osteosarcoma...
  30. Tunn P, Pomraenke D, Goerling U, Hohenberger P. Functional outcome after endoprosthetic limb-salvage therapy of primary bone tumours--a comparative analysis using the MSTS score, the TESS and the RNL index. Int Orthop. 2008;32:619-25 pubmed
    ..Parallel recording of the MSTS score, TESS and RNL index provides a better measure reflecting the complex situation of the patients by combining objective and subjective parameters...
  31. Hameed M, Blacksin M, Das K, Patterson F, Benevenia J, Aisner S. Cortical chondroblastoma: report of a case and literature review of this lesion reported in unusual locations. Skeletal Radiol. 2006;35:295-7 pubmed
    ..Biopsy revealed a chondroblastoma, and the patient subsequently underwent a total curettage of the lesion with cancellous bone graft from the iliac crest...
  32. Ruiz Tovar J, Reguero Callejas M, Arano Bermejo J, Capote Armas L, González Palacios Martínez F, Cabañas Navarro L. Malignant mixed Mullerian tumors. Clin Transl Oncol. 2006;8:129-32 pubmed
    ..Because of the high incidence of recurrence and poor prognosis of these tumours, they should be studied and managed by a multidisciplinary team composed by surgeons, oncologists, radiotherapists and pathologists...
  33. Sokolovski V, Voloshin V, Aliev M, Zubikov V, Saravanan S, Martynenko D, et al. Total hip replacement for proximal femoral tumours: our midterm results. Int Orthop. 2006;30:399-402 pubmed
    ..During our midterm survival analysis, functional results were excellent in 25% of patients, good in 57%, fair in 12%, and poor in 6%...
  34. Sharma S, Turcotte R, Isler M, Wong C. Cemented rotating hinge endoprosthesis for limb salvage of distal femur tumors. Clin Orthop Relat Res. 2006;450:28-32 pubmed
    ..Musculoskeletal Tumor Society 1987 scores averaged 30 and Toronto Extremity Salvage Scores averaged 77.6 at latest followup. Cemented endoprosthesis is a reliable procedure after resection of the distal femur for tumors...
  35. Nazar J, Nowakowski A, Michalski P, Jaszczak T, Bartochowski Ł. [Indications for usage of oncological prostheses in the treatment of proximal femur methastases]. Chir Narzadow Ruchu Ortop Pol. 2008;73:355-8 pubmed
    ..At the appropriately selected group of patients application of onclological prosthesis lets for restoring the function of the limb, reducing or bearing pain complaints or removing the entire methastasis...
  36. Subhas N, Bauer T, Joyce M, Sundaram M. The "mini brain" appearance of plasmacytoma in the appendicular skeleton. Skeletal Radiol. 2008;37:771-4 pubmed publisher
    ..This case illustrates a rare but seemingly characteristic "mini brain" appearance of plasmacytoma, which, to date, has only been reported in the spine and has not been observed in other bony lesions...
  37. Hanna S, Sewell M, Aston W, Pollock R, Skinner J, Cannon S, et al. Femoral diaphyseal endoprosthetic reconstruction after segmental resection of primary bone tumours. J Bone Joint Surg Br. 2010;92:867-74 pubmed publisher
    ..It allows immediate weight-bearing, is associated with a good long-term functional outcome, has an acceptable complication and revision rate and, most importantly, does not appear to compromise patient survival...
  38. Cantwell C, Kenny P, Eustace S. Low radiation dose CT technique for guidance of radiofrequency ablation of osteoid osteoma. Clin Radiol. 2008;63:449-52 pubmed publisher
  39. Bispo Junior R, Guedes A. Parosteal lipoma of the femur with hyperostosis: case report and literature review. Clinics (Sao Paulo). 2007;62:647-52 pubmed
  40. Charfi L, Mrad K, Karray S, Sassi S, Driss M, Abbes I, et al. [Epithelioid hemangioendothelioma of bone complicated by femoral fracture]. Rev Chir Orthop Reparatrice Appar Mot. 2005;91:788-91 pubmed
    ..Prognosis is a subject of debate as the tumor is considered to exhibit intermediate malignancy by some authors while other consider it to be a malignant tumor...
  41. Annapureddy S, Smith A, Martin W, Charnley G. Osteosclerotic secondaries from oesophageal carcinoma mimicking a primary bone tumour: a case report and literature review. Int J Clin Pract. 2008;62:500-2 pubmed publisher
  42. Shapiro M, Wistinghausen B, Midulla P, Chin C. Metastatic osteosarcoma presenting as a single pulmonary microembolus. J Pediatr Surg. 2011;46:574-6 pubmed publisher
    ..Pulmonary tumor embolism should be considered in the differential diagnosis in patients with cancer who present with dyspnea. The differentiation of tumor embolus from other causes of dyspnea is important for treatment plan...
  43. Virayavanich W, Singh R, O Donnell R, Horvai A, Goldsby R, Link T. Osteoid osteoma of the femur in a 7-month-old infant treated with radiofrequency ablation. Skeletal Radiol. 2010;39:1145-9 pubmed publisher
    ..In summary, this case report shows that osteoid osteoma can present in early infancy and can be successfully treated with RFA at this age, however, recurrence after the procedure can occur and close follow-up is recommended...
  44. Bharatnur S, Naik C, Swethadri G, Fernandes H, Shekhar J, Marla N. Fine needle aspiration cytology of benign fibrous histiocytoma of bone: a case report. Acta Cytol. 2010;54:89-91 pubmed
    ..Histology revealed a pure BFH of bone. The current case reveals the cytomorphologic features of BFH of bone. Cytology may permit the preoperative recognition of the lesion, allowing a more sound therapeutic approach. ..
  45. Roarke M, Nguyen B. PET/CT localization of phosphaturic mesenchymal neoplasm causing tumor-induced osteomalacia. Clin Nucl Med. 2007;32:300-1 pubmed
  46. Pérez Serna A, Moreno Hoyos L, Ramírrez Valdivia S. [Conservative surgery as an alternative treatment of a knee osteosarcoma in the presence of a pathological fracture]. Acta Ortop Mex. 2009;23:351-7 pubmed
    ..Conservative surgery is inappropriate; however, preoperative chemotherapy and a good choice of conservative treatment are an alternative...
  47. Huang Z, Lou C, Fang X. [Value of thallium-201 scintigraphy in assessment of neoadjuvant chemotherapy for osteosarcoma]. Zhonghua Zhong Liu Za Zhi. 2009;31:769-72 pubmed
    ..To investigate the significance of Tl-201 scintigraphy for assessment of neoadjuvant chemotherapy for osteosarcoma...
  48. Arkader A, Viola D, Morris C, Boland P, Healey J. Coaxial extendible knee equalizes limb length in children with osteogenic sarcoma. Clin Orthop Relat Res. 2007;459:60-5 pubmed
    ..Femoral diameter growth may contribute to loosening. Early experience with this extendible implant is promising...
  49. Asavamongkolgul A, Thanakarasombat S. Treatment of bone tumors in the femoral trochanteric area. J Med Assoc Thai. 2012;95 Suppl 9:S129-37 pubmed
    ..To report the management of bone tumor in the femoral trochanteric area in terms of safety,functional outcome and patient satisfaction...
  50. Gupta A, Saifuddin A, Briggs T, Flanagan A. Subperiosteal hemangioendothelioma of the femur. Skeletal Radiol. 2006;35:793-6 pubmed
    ..We report a case of haemangioendothelioma localised to the subperiosteum of the femur, a site not previously described for this lesion. The nomenclature for vascular neoplasms in bone is discussed...
  51. Hwang N, Nandra R, Grimer R, Carter S, Tillman R, Abudu A, et al. Massive endoprosthetic replacement for bone metastases resulting from renal cell carcinoma: factors influencing patient survival. Eur J Surg Oncol. 2014;40:429-34 pubmed publisher
    ..Surgery remains the main treatment of bone metastases due to renal cell carcinoma (RCC). We reviewed 135 patients treated with resection and endoprosthetic replacement (EPR) and examined clinico-pathological factors predicting survival...
  52. Etchebehere M, Lin P, Bird J, Satcher R, Moon B, Yu J, et al. Patellar Resurfacing: Does It Affect Outcomes of Distal Femoral Replacement After Distal Femoral Resection?. J Bone Joint Surg Am. 2016;98:544-51 pubmed publisher
    ..Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence. ..
  53. Wang W, Wu C, Gu Y, Li M. Percutaneous osteoplasty for the management of a femoral head metastasis: a case report. Korean J Radiol. 2009;10:641-4 pubmed publisher
    ..During the follow-up period, the patient experienced sustained pain relief and improvement of quality of life that persisted for more than three months...