hamartoma

Summary

Summary: A focal malformation resembling a neoplasm, composed of an overgrowth of mature cells and tissues that normally occur in the affected area.

Top Publications

  1. Portale T, Mosca F, Vicari S, Pulvirenti G, Fichera S, Salomone E, et al. Myoepithelial hamartoma of the stomach simulating a gastric carcinoma. A case report. Tumori. 2007;93:220-2 pubmed
    Myoepithelial hamartoma is a very rare submucosal tumor of the stomach. Magnus-Alsleben first described 5 cases of this tumor in 1903. More recently (1993) Vandelli et al. published a review of the literature comprising only 33 cases...
  2. Pati S, Sollman M, Fife T, Ng Y. Diagnosis and management of epilepsy associated with hypothalamic hamartoma: an evidence-based systematic review. J Child Neurol. 2013;28:909-16 pubmed publisher
  3. Lee D, Cho T, Lee H, Lee K, Moon H, Park M, et al. Disturbed osteoblastic differentiation of fibrous hamartoma cell from congenital pseudarthrosis of the tibia associated with neurofibromatosis type I. Clin Orthop Surg. 2011;3:230-7 pubmed publisher
    Fibrous hamartoma is the key pathology of congenital pseudarthrosis of the tibia (CPT), which was shown to have low osteogenicity and high osteoclastogenicity...
  4. Braatz B, Evans R, Kelman A, Cheng W. Perinatal evolution of mesenchymal hamartoma of the chest wall. J Pediatr Surg. 2010;45:e37-40 pubmed publisher
    Mesenchymal hamartoma of the chest wall (MHCW) is a rare condition. Previously, surgical resection has been advocated with considerable post-operative morbidity...
  5. Gasljević G, Lamovec J, Jancar J. Undifferentiated (embryonal) liver sarcoma: synchronous and metachronous occurrence with neoplasms other than mesenchymal liver hamartoma. Ann Diagn Pathol. 2011;15:250-6 pubmed publisher
    ..The association of UELS with neoplasm other than mesenchymal liver hamartoma is exceedingly rare...
  6. Kocova M, Zdraveska N, Sukarova Angelovska E. Unique concurrent appearance of two rare conditions in a young girl: central precocious puberty due to hypothalamic hamartoma and uncommon type of diabetes. J Pediatr Endocrinol Metab. 2011;24:815-8 pubmed
    ..We present a girl with early onset of central precocious puberty at the age of 8 months, due to hypothalamic hamartoma. Treatment with depot of a GnRH analog for a period of 9 years and 8 months was successful, and her puberty ..
  7. Mizuta N, Sakaguchi K, Mizuta M, Imai A, Nakatsukasa K, Morita M, et al. Myoid hamartoma of the breast that proved difficult to diagnose: a case report. World J Surg Oncol. 2012;10:12 pubmed publisher
    ..Histologically, the tumor was identified as fibroadenoma. A case of myoid hamartoma of the breast that proved difficult to diagnose is reported, and discussed with reference to the literature.
  8. Basso S, Sulfaro S, Marzano B, Fanti G, Chiara G, Lumachi F. Incidentally discovered asymptomatic splenic hamartoma with rapidly expansive growth: a case report. In Vivo. 2012;26:1049-52 pubmed
    Splenic hamartoma (SH) is a very rare benign vascular lesion, usually asymptomatic. Although infrequent, it must be differentiated from malignant lesions, such as lymphoma or metastases, or other vascular neoplasms of the spleen...
  9. Fitzhugh V, Mirani N. Respiratory epithelial adenomatoid hamartoma: a review. Head Neck Pathol. 2008;2:203-8 pubmed publisher
    Respiratory epithelial adenomatoid hamartoma (REAH) is an uncommon lesion of the upper aerodigestive tract first described by Wenig and Heffner in 1995 as prominent glandular proliferations lined by ciliated respiratory epithelium ..

More Information

Publications83

  1. Martin K, Rossi V, Ferrucci S, Pian D. Retinal astrocytic hamartoma. Optometry. 2010;81:221-33 pubmed publisher
    ..Although the finding may point toward a systemic association, it can also be found incidentally on retinal examination as an isolated presentation...
  2. Matsumoto T, Shimizu T, Aoshima Y, Oda H, Kikuchi K, Katsura H, et al. Endobronchial hamartoma with obstructive pneumonia due to Nocardia asiatica. Gen Thorac Cardiovasc Surg. 2011;59:141-4 pubmed publisher
    ..could not be achieved with a high-frequency snare, although the patient was preoperatively diagnosed as having hamartoma. The patient subsequently underwent resection of the right lower lobe due to his deteriorated clinical condition...
  3. Mathur S, Gupta R, Seith A, Agarwala S, Subramanian S, Gupta S. Aspiration cytology of mesenchymal hamartoma of the chest wall in an infant: a case report. Acta Cytol. 2010;54:63-5 pubmed
    Mesenchymal hamartoma of the chest wall is an extremely uncommon lesion of infants...
  4. Abla A, Rekate H, Wilson D, Wait S, Uschold T, Prenger E, et al. Orbitozygomatic resection for hypothalamic hamartoma and epilepsy: patient selection and outcome. Childs Nerv Syst. 2011;27:265-77 pubmed publisher
    ..This study aims to examine the outcomes of ten patients after orbitozygomatic (OZ) pterional surgery in cases of refractory epilepsy caused by hypothalamic hamartomas (HH)...
  5. Kokkinos V, Zountsas B, Kontogiannis K, Garganis K. Epileptogenic networks in two patients with hypothalamic hamartoma. Brain Topogr. 2012;25:327-31 pubmed publisher
    ..The differences in the neural networks implicated may account for differences in clinical manifestation of seizures owing to HH...
  6. Cetinkaya E, Gunluoglu G, Eyhan S, Gunluoglu M, Dincer S. A hamartoma located in the trachea. Ann Thorac Cardiovasc Surg. 2011;17:504-6 pubmed
    b>Hamartoma is rarely found to be localized in the trachea. In the literature, only about ten cases have been reported...
  7. Yang A, Zhang K, Zhang J, Liu H, Chen N, Ge M, et al. Temporal lobe epilepsy with hypothalamic hamartoma: a rare case. Chin Med J (Engl). 2011;124:1114-7 pubmed
    Refractory gelastic seizure is one of the most common clinical manifestations in patients with hypothalamic hamartoma (HH) and HH is usually regarded as the epileptogenic focus...
  8. Tucker S, Cooper K, Brownschidle S, Wilcox R. Embryonal (undifferentiated) sarcoma of the liver with peripheral angiosarcoma differentiation arising in a mesenchymal hamartoma in an adult patient. Int J Surg Pathol. 2012;20:297-300 pubmed publisher
    ..We are presenting a case of a 74-year-old woman diagnosed with an ESL arising from a mesenchymal hamartoma of the liver (MHL). Both lesions occur typically in childhood, with only rare reported cases in adults...
  9. Stang A, Keles H, Hentschke S, von Seydewitz C, Dahlke J, Habermann C, et al. Incidentally detected splenic lesions in ultrasound: does contrast-enhanced ultrasonography improve the differentiation of benign hemangioma/hamartoma from malignant lesions?. Ultraschall Med. 2011;32:582-92 pubmed publisher
    The aim of the study was to identify and validate enhancing features for differentiating benign vascular neoplasms of the hemangioma/hamartoma type from malignant splenic lesions on contrast-enhanced ultrasonography (CEUS).
  10. Chiang C, Tsai M, Chen C. MRI diagnosis of fibrolipomatous hamartoma of the median nerve and associated macrodystrophia lipomatosa. J Chin Med Assoc. 2010;73:499-502 pubmed publisher
    Fibrolipomatous hamartoma is an uncommon congenital disorder, which is characterized by disproportionate hyperplasia of adipose tissue infiltrating along the perineurium, the epineurium and the affected nerve trajectory...
  11. Gupta S, Singh O, Hastir A, Arora G, Sabharwal G, Mishra H. Breast hamartoma with intrathoracic extension in a 13-year-old boy. J Cancer Res Ther. 2010;6:86-8 pubmed publisher
    Breast hamartoma is a rare tumor that has been reported only thrice in a male breast. The pediatric age group is seldom involved...
  12. Rodrigues A, Coelho D, Dias Júnior S, Jacomelli M, Scordamaglio P, Figueiredo V. Minimally invasive bronchoscopic resection of benign tumors of the bronchi. J Bras Pneumol. 2011;37:796-800 pubmed
    ..Primary benign tumors of the trachea and main bronchi are uncommon. Interventional bronchoscopy allows the diagnosis and the treatment of some of these lesions...
  13. Conrad D, Chaplin A, Walsh N, Pasternak S. Extensive neurocristic hamartoma with bone marrow involvement. Am J Dermatopathol. 2010;32:486-8 pubmed publisher
    Cutaneous neurocristic hamartoma (NCH) is a rare, pigmented lesion consisting of cells that aberrantly develop from the neurocrest...
  14. Demir R, Schmid A, Hohenberger W, Agaimy A. Angiolipomatous mesenchymal hamartoma (angiolipomatosis) of the sigmoid mesocolon. Int J Clin Exp Pathol. 2011;4:210-4 pubmed
    ..Primary mesenteric tumors are exceedingly rare and may thus pose a diagnostic challenge. They encompass both benign and malignant neoplasms as well as reactive and idiopathic tumefactive fibroinflammatory lesions...
  15. Rosenfeld J. The evolution of treatment for hypothalamic hamartoma: a personal odyssey. Neurosurg Focus. 2011;30:E1 pubmed
    The prognosis for patients with hypothalamic hamartoma has improved dramatically over the last 20 years, for 3 main reasons. First, because of improved understanding of the anatomy and pathophysiology of these varied lesions...
  16. Li S, Thangapazham R, Wang J, Rajesh S, Kao T, Sperling L, et al. Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis. Nat Commun. 2011;2:235 pubmed publisher
    ..These studies indicate that TSC2-null cells are the inciting cells for TSC skin hamartomas, and suggest that studies on hamartomas will provide insights into tissue morphogenesis and regeneration. ..
  17. Zhang M, Matsuo K, Yamashita Y, Takahashi T. Leiomyomatous hamartoma of the midline maxillary gingival presenting as a congenital epulis: a case report with an immunohistochemical study. Int J Oral Maxillofac Surg. 2011;40:1322-6 pubmed publisher
    ..The immunohistochemical staining findings for ?-smooth-muscle actin, desmin and S-100 protein were all positive. The histological diagnosis was therefore leiomyomatous hamartoma, based on clinical microscopic observations.
  18. Venkatanarasimha N, Thomas R, Armstrong E, Shirley J, Fox B, Jackson S. Imaging features of ductal plate malformations in adults. Clin Radiol. 2011;66:1086-93 pubmed publisher
    ..cyst, Caroli's disease and Caroli's syndrome, adult autosomal dominant polycystic liver disease, and biliary hamartoma. The hepatic lesions can be associated with renal anomalies such as autosomal recessive polycystic kidney ..
  19. Wang J, Ma X, Ren F, Zuo C, Tian J, Wang Z, et al. Multi-modality imaging findings of splenic hamartoma: a report of nine cases and review of the literature. Abdom Imaging. 2013;38:154-62 pubmed publisher
    ..To investigate the presentation of splenic hamartomas (SHs) on ultrasonography (US), CT and MRI...
  20. Boccaletti V, Accorsi P, Pinelli L, Ungari M, Giordano L, Neri I, et al. Congenital systematized basaloid follicular hamartoma with microphthalmia and hemimegalencephaly. Pediatr Dermatol. 2011;28:555-60 pubmed publisher
    ..Here, we describe a 5-year-old boy with basaloid follicular hamartoma affecting the left side of the body in linear multiple bands, following Blaschko lines...
  21. Chu L, Seed M, Howse E, Ryan G, Grosse Wortmann L. Mesenchymal hamartoma: prenatal diagnosis by MRI. Pediatr Radiol. 2011;41:781-4 pubmed publisher
    ..An awareness of the characteristic imaging findings will allow accurate diagnosis of this condition, even prenatally, and thus facilitate appropriate perinatal management and surgical planning...
  22. Hur S, Han J, Kim M, Bae J, Choi B. Brunner's gland hamartoma: computed tomographic findings with histopathologic correlation in 9 cases. J Comput Assist Tomogr. 2010;34:543-7 pubmed publisher
    To describe the computed tomographic (CT) features of Brunner's gland hamartoma with histopathologic correlation.
  23. Choi N, Ko E. Invasive ductal carcinoma in a mammary hamartoma: case report and review of the literature. Korean J Radiol. 2010;11:687-91 pubmed publisher
    ..Only 14 cases of carcinomas associated with a hamartoma have been documented in the literature...
  24. Ko M, Jung W, Cha E, Choi H. A rare case of recurrent myoid hamartoma mimicking malignancy: imaging appearances. Korean J Radiol. 2010;11:683-6 pubmed publisher
    Myoid hamartoma is an uncommon type of breast hamartoma and its recurrence is very rare. We report the imaging appearance of an unusual case of recurrent myoid hamartoma of the breast mimicking malignancy in a 43-year-old woman...
  25. Kim Y, Rha S, Oh S, Jung S, Shin Y, Choi B, et al. Imaging findings of intrahepatic bile duct adenoma (peribiliary gland hamartoma): a case report and literature review. Korean J Radiol. 2010;11:560-5 pubmed publisher
    ..Although rare, bile duct adenoma should be considered as a differential diagnosis of a small hypervascular tumor located in the periphery of liver. Focal cystic change and intratumoral hemorrhage may occur...
  26. Choi J, Kim D. Treatment modalities for intractable epilepsy in hypothalamic hamartoma. Adv Tech Stand Neurosurg. 2012;39:117-30 pubmed publisher
    Hypothalamic hamartoma (HH) is usually associated with refractory epilepsy, cognitive impairment, and behavioral disturbance. There is now increasing evidence that HH can be treated effectively with a variety of neurosurgical approaches...
  27. Prusac I, Jurić I, Lamovec J, Culic V. Angiomyomatous hamartoma of the popliteal lymph nodes in a patient with Klippel-Trenaunay syndrome: case report. Fetal Pediatr Pathol. 2011;30:320-4 pubmed publisher
    We present a case of angiomyomatous hamartoma (AMH) in the popliteal region of a patient with Klippel-Trenaunay syndrome...
  28. Scarella T, Macken M, Gerard E, Schuele S. Psychogenic gelastic seizures in a patient with hypothalamic hamartoma. Epileptic Disord. 2012;14:187-9 pubmed publisher
    Gelastic seizures are classically associated with hypothalamic hamartoma. The most effective treatment for gelastic epilepsy is surgery, although confirming that a hypothalamic hamartoma is an epileptic lesion prior to surgical ..
  29. Alves C, Barbosa V, Machado M. Giant hypothalamic hamartoma: case report and literature review. Childs Nerv Syst. 2013;29:513-6 pubmed publisher
    ..Hypothalamic hamartomas are very rare (1:200,000) and range in size from 17.9 to 18 mm. When their dimensions exceed 30-40 mm, they are classified as giant hypothalamic hamartomas...
  30. Torrelo A, Hadj Rabia S, Colmenero I, Piston R, Sybert V, Hilari Carbonell H, et al. Folliculocystic and collagen hamartoma of tuberous sclerosis complex. J Am Acad Dermatol. 2012;66:617-21 pubmed publisher
    ..Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by tumors and hamartomas in several organs including the skin...
  31. Striano S, Santulli L, Ianniciello M, Ferretti M, Romanelli P, Striano P. The gelastic seizures-hypothalamic hamartoma syndrome: facts, hypotheses, and perspectives. Epilepsy Behav. 2012;24:7-13 pubmed publisher
    Hypothalamic hamartoma (HH) can be associated with a wide spectrum of epileptic conditions, ranging from a mild form with seizures characterized by urge to laugh and no cognitive involvement up to a catastrophic encephalopathy with early ..
  32. Cheung C, Parrent A, Burneo J. Gelastic seizures: not always hypothalamic hamartoma. Epileptic Disord. 2007;9:453-8 pubmed
    ..This case report presents a 29-year-old woman who was successfully rendered free of gelastic seizures after resection of a frontal cortical dysplasia, localized through MRI and SPECT imaging.[Published with video sequences]. ..
  33. Wu J, Dechon J, Xue F, Li G, Ellsworth K, Gao M, et al. GABA(A) receptor-mediated excitation in dissociated neurons from human hypothalamic hamartomas. Exp Neurol. 2008;213:397-404 pubmed publisher
    The cellular mechanisms underlying intrinsic epileptogenesis in human hypothalamic hamartoma (HH) are unknown...
  34. Song D, Park J, Hur B, Ro J. Carcinoid tumor arising in a tailgut cyst of the anorectal junction with distant metastasis: a case report and review of the literature. Arch Pathol Lab Med. 2004;128:578-80 pubmed
    ..This case was unique because the tumor occurred at the anorectal junction, not in the retrorectal space, and unlike previously reported cases showed aggressive behavior and distant metastases. ..
  35. Delbrouck C, Fernandez Aguilar S, Choufani G, Hassid S. Respiratory epithelial adenomatoid hamartoma associated with nasal polyposis. Am J Otolaryngol. 2004;25:282-4 pubmed
    b>Hamartoma is a rare, non-neoplastic tumor characterized by an abnormal mixture of tissues, which are indigenous to the region. They are rare in the nasal cavity...
  36. Yu R, Zhang S, Hua J. Imaging findings of splenic hamartoma. World J Gastroenterol. 2004;10:2613-5 pubmed
    To assess CT and MR manifestations and their diagnostic value in splenic hamartoma with review of literatures. We described a woman who was accidentally found to have a splenic tumor by ultrasound of the abdomen...
  37. Ali T, Beyer G, Taylor M, Volpe C, Papadimitriou J. Splenic hamartoma: immunohistochemical and ultrastructural profile of two cases. Int J Surg Pathol. 2005;13:103-11 pubmed
    Splenic hamartoma (SH) is a rare, benign lesion. We present 2 cases, both in females (2 and 30 years, respectively) with multiple urinary tract infections, and left upper quadrant abdominal pain...
  38. Afshar A. Carpal tunnel syndrome due to lipofibromatous hamartoma of the median nerve. Arch Iran Med. 2010;13:45-7 pubmed
    This report describes a rare case of secondary carpal tunnel syndrome due to a lipofibromatous hamartoma of the median nerve...
  39. Shimotake T, Fumino S, Aoi S, Tsuda T, Iwai N. Respiratory insufficiency in a newborn with mesenchymal hamartoma of the chest wall occupying the thoracic cavity. J Pediatr Surg. 2005;40:E13-6 pubmed
    The authors describe a newborn patient with mesenchymal hamartoma of the chest wall associated with pulmonary hypoplasia...
  40. Al Habeeb A, Alkhalidi H, Idikio H, Ghazarian D. Cutaneous solitary neural hamartoma: report of an unusual case. Am J Dermatopathol. 2009;31:484-6 pubmed publisher
    ..To our knowledge, there is no previous report of such cutaneous solitary neural hamartoma. Our case occurred in a 51-year-old man with pain and paresthesia in the right shoulder associated with a nodule ..
  41. Bains R, Kotwal A, Saeed W. Recurrent carpal tunnel syndrome in a child due to fibrolipomatous hamartoma of the median nerve successfully treated by limited excision and decompression. J Plast Reconstr Aesthet Surg. 2006;59:1394-7 pubmed
    We present a case of recurrent carpal tunnel syndrome in a child caused by fibrolipomatous hamartoma of the median nerve which was successfully treated by limited excision of the fibrolipomatous tissue and decompression.
  42. Picciotti P, Calò L, Mule A, Maggiore C, Scarano E. Rhino sinusal bilateral hamartoma: a case report. Auris Nasus Larynx. 2008;35:569-71 pubmed publisher
    The hamartoma is a benign rare tumor constituted by a mixture of tissue. It is very unusual in the nasal cavity. The objective of the study is to describe an unusual case of bilateral nasal hamartoma...
  43. Gualtieri M, Cocci A, Monti S, Olivero D. Surgical removal of a localised vascular hepatic hamartoma in a dog. Aust Vet J. 2009;87:360-2 pubmed publisher
    ..Histologic evaluation of the mass supported a vascular hepatic hamartoma. Vascular hamartomas are rare malformations in animals and only two cases have been reported in the dog...
  44. Bevona C, Tannous Z, Tsao H. Dermal melanocytic proliferation with features of a plaque-type blue nevus and neurocristic hamartoma. J Am Acad Dermatol. 2003;49:924-9 pubmed
    ..In addition, BN and NCH might differ in their potential to develop into a malignancy. We describe a patient with a lesion showing features of both a plaque-type BN and NCH...
  45. Cornette J, Festen S, van den Hoonaard T, Steegers E. Mesenchymal hamartoma of the liver: a benign tumor with deceptive prognosis in the perinatal period. Case report and review of the literature. Fetal Diagn Ther. 2009;25:196-202 pubmed publisher
    This article reports a case of perinatal mesenchymal hepatic hamartoma and reviews the literature on the subject. A fetus presented with polyhydramnios and a large multiloculated cystic abdominal mass at 33 weeks of gestation...
  46. Boman F, Bossard C, Fabre M, Diab N, Bonnevalle M, Boccon Gibod L. Mesenchymal hamartomas of the liver may be associated with increased serum alpha foetoprotein concentrations and mimic hepatoblastomas. Eur J Pediatr Surg. 2004;14:63-6 pubmed
    A mesenchymal hamartoma (MH) of the liver in a seven-month-old girl was associated with slightly elevated alpha fetoprotein (AFP) concentrations (320 microg/L, normal < 25 after six months of age)...
  47. Wu J, Chang Y, Li G, Xue F, Dechon J, Ellsworth K, et al. Electrophysiological properties and subunit composition of GABAA receptors in patients with gelastic seizures and hypothalamic hamartoma. J Neurophysiol. 2007;98:5-15 pubmed
    ..Whether this is true for patients with gelastic seizures and hypothalamic hamartoma (HH) is unknown...
  48. Jeong E, Park H, Oh S, Lee J, Cho B. Late-onset eccrine angiomatous hamartoma on the forehead. Int J Dermatol. 2006;45:598-9 pubmed
    ..These findings are consistent with eccrine angiomatous hamartoma. There was no change in the lesion during the 1-year follow-up period.
  49. Vargas P, Carlos Bregni R, Mosqueda Taylor A, Cuairan Ruidíaz V, Lopes M, de Almeida O. Adenomatoid dentinoma or adenomatoid odontogenic hamartoma: what is the better term to denominate this uncommon odontogenic lesion?. Oral Dis. 2006;12:200-3 pubmed
    ..histological and electron microscopical features we proposed the diagnosis of adenomatoid odontogenic hamartoma. Treatment consisted of surgical removal, and no recurrence was observed...
  50. Pervatikar S, Rao R, Dinesh U, Parameswaraiah S. Large mammary hamartoma with focal invasive ductal carcinoma. Indian J Pathol Microbiol. 2009;52:249-51 pubmed
    ..Mammary hamartomas are benign lesions but, on exceedingly rare occasions, they may be involved by incidental, coexisting carcinoma, as illustrated in this case report...
  51. Selch M, Gorgulho A, Mattozo C, Solberg T, Cabatan Awang C, DeSalles A. Linear accelerator stereotactic radiosurgery for the treatment of gelastic seizures due to hypothalamic hamartoma. Minim Invasive Neurosurg. 2005;48:310-4 pubmed
    ..stereotactic radiosurgery (SRS) for the treatment of gelastic seizures associated with a hypothalamic hamartoma. The authors reviewed the results of linear accelerator (LINAC) radiosurgery for patients with medically ..
  52. Kessler H, Unterman B. Respiratory epithelial adenomatoid hamartoma of the maxillary sinus presenting as a periapical radiolucency: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;97:607-12 pubmed
    We report a case of respiratory epithelial adenomatoid hamartoma of the left maxillary sinus that initially presented as a periapical radiolucency involving the left maxillary first molar...
  53. Lakshminarayanan R, Konia T, Welborn J. Fibrous hamartoma of infancy: a case report with associated cytogenetic findings. Arch Pathol Lab Med. 2005;129:520-2 pubmed
    ..Histology revealed the typical features of a fibrous hamartoma. Cytogenetic studies revealed a reciprocal translocation, t(2;3)(q31;q21), as the sole abnormality...
  54. Zaitoun H, Triantfyllou A. Smooth muscle hamartoma of the hard palate. J Oral Pathol Med. 2007;36:245-9 pubmed
    ..The lesion could be attributed to dysgenesis affecting media of vessels emerging from the incisive foramen. Intra-oral smooth muscle hamartomas tend to favour regions featuring complex developmental events...
  55. Iusco D, Roncoroni L, Violi V, Donadei E, Sarli L. Brunner's gland hamartoma: 'over-treatment' of a voluminous mass simulating a malignancy of the pancreatic-duodenal area. JOP. 2005;6:348-53 pubmed
    ..When Brunner's gland hyperplasia does not have common dimensions, it may also mimic a malignancy of the duodenal-pancreatic area. In this case, a biopsy is indicated even though its result may be not informative...
  56. Boudewyns A, van Dinther J, Colpaert C. Sinonasal fibro-osseous hamartoma: case presentation and differential diagnosis with other fibro-osseous lesions involving the paranasal sinuses. Eur Arch Otorhinolaryngol. 2006;263:276-81 pubmed
    ..A combination of clinical, radiographic and histological information permitted a diagnosis of a benign fibro-osseous lesion: sinonasal hamartoma. The benign nature of this tumor justified a conservative follow-up.
  57. Chang H, Jin S, Park C, Park Y, Jang J, Park C, et al. Mesenchymal hamartomas of the liver: comparison of clinicopathologic features between cystic and solid forms. J Korean Med Sci. 2006;21:63-8 pubmed
    Mesenchymal hamartoma (MH) of the liver is an uncommon benign lesion related to ductal plate malformation. It is usually cystic and mainly composed of myxoid mesenchymal tissue with tortuous or cystic bile ducts...
  58. Park S, Oh K, Kim E, Son E, Chung W. Sonographic findings of breast hamartoma: emphasis on compressibility. Yonsei Med J. 2003;44:847-54 pubmed
    The characteristic features of hamartoma in terms of discrepancies in mammographic and sonographic shapes of the mass were evaluated...
  59. Imaji R, Goto T, Takahashi Y, Akiyama T, Yamadori I. A case of recurrent and synchronous fibrous hamartoma of infancy. Pediatr Surg Int. 2005;21:119-20 pubmed
    We retrospectively reviewed the chart of a patient with recurrent fibrous hamartoma of infancy (FHI). This lesion presented as a gradually enlarging mass on the child's buttock...
  60. Ruiz Tovar J, Reguero Callejas M, Aláez A, Ramiro C, Rojo R, Collado M, et al. Infiltrating ductal carcinoma and ductal carcinoma in situ associated with mammary hamartoma. Breast J. 2006;12:368-70 pubmed
    Mammary hamartoma is a rare nonmalignant lesion. Only 11 cases of carcinoma associated with hamartoma have been previously described in the literature...
  61. Rajaram V, Knezevich S, Bove K, Perry A, Pfeifer J. DNA sequence of the translocation breakpoints in undifferentiated embryonal sarcoma arising in mesenchymal hamartoma of the liver harboring the t(11;19)(q11;q13.4) translocation. Genes Chromosomes Cancer. 2007;46:508-13 pubmed
    ..sarcoma of the liver is a highly malignant and aggressive tumor that occasionally arises within mesenchymal hamartoma of the liver (MHL), a benign tumor that typically occurs in young children...
  62. Murat A, Ozdemir H, Yildirim H, Poyraz A, Ozercan R. Hamartoma of the breast. Australas Radiol. 2007;51 Spec No.:B37-9 pubmed
    Breast hamartoma is a rare benign tumour that leads to unilateral breast enlargement without a palpable localized mass lesion. Histologically, a hamartoma consists of varying amounts of adipose, gland, fibre and smooth muscle tissue...
  63. Thrall M, Jessurun J, Stelow E, Adsay N, Vickers S, Whitson A, et al. Multicystic adenomatoid hamartoma of the pancreas: a hitherto undescribed pancreatic tumor occurring in a 3-year-old boy. Pediatr Dev Pathol. 2008;11:314-20 pubmed
    ..quot; As a result of its superficial resemblance to Stocker type 2 cystic adenomatoid malformation of the lung, we are proposing the name "multicystic adenomatoid hamartoma" for this lesion.
  64. Mauro C, McGough R, Rao U. Angiomyomatous hamartoma of a popliteal lymph node: an unusual cause of posterior knee pain. Ann Diagn Pathol. 2008;12:372-4 pubmed publisher
    Angiomyomatous hamartoma is a primary vascular tumor primarily found in the inguinal and femoral lymph nodes characterized by the replacement of nodal tissue by smooth muscle cells and fibrous tissue in sclerotic lymphatic stroma...
  65. Hornick J, Lauwers G, Odze R. Immunohistochemistry can help distinguish metastatic pancreatic adenocarcinomas from bile duct adenomas and hamartomas of the liver. Am J Surg Pathol. 2005;29:381-9 pubmed
    ..Although p63 and AMACR are also specific for pancreatic adenocarcinoma, their low sensitivity limits their use in clinical practice...
  66. Gatti G, Mazzarol G, Simsek S, Viale G. Breast hamartoma: a case report. Breast Cancer Res Treat. 2005;89:145-7 pubmed
    Breast hamartoma is an uncommon benign lesion, composed of varying amounts of fatty, fibrous and glandular elements...
  67. Narasimhan K, Radotra B, Harish J, Rao K. Conservative management of giant hepatic mesenchymal hamartoma. Indian J Gastroenterol. 2004;23:26 pubmed
    We report a six-month-old male infant with mesenchymal hamartoma of the liver which was left untreated. Repeat CT scan 1 year later showed regression and calcification of the tumor. The child is well 3 years later.
  68. Fohlen M, Lellouch A, Delalande O. Hypothalamic hamartoma with refractory epilepsy: surgical procedures and results in 18 patients. Epileptic Disord. 2003;5:267-73 pubmed
    To study the surgical procedures and results on seizures, in 18 patients with refractory epilepsy due to hypothalamic hamartoma.
  69. Zhang X, Dong F, Dai R, Yu W. Surgical management of epiretinal membrane in combined hamartomas of the retina and retinal pigment epithelium. Retina. 2010;30:305-9 pubmed
    ..The purpose of this study was to evaluate the surgical outcome of combined hamartomas of the retina and retinal pigment epithelium in five patients...
  70. Shields C, Mashayekhi A, Dai V, Materin M, Shields J. Optical coherence tomographic findings of combined hamartoma of the retina and retinal pigment epithelium in 11 patients. Arch Ophthalmol. 2005;123:1746-50 pubmed
  71. Tsunemi Y, Shimazu K, Saeki H, Ihn H, Tamaki K. Eccrine angiomatous hamartoma with massive mucin deposition. Eur J Dermatol. 2005;15:291-2 pubmed
    Eccrine angiomatous hamartoma (EAH) is a rare condition characterized histologically by an increased number of eccrine structures and numerous vascular elements...
  72. Chou Y, Chiou H, Tiu C, Chiou S, Hsia C, Tsay S. Splenic hamartoma: presentation on contrast-enhanced sonography. J Clin Ultrasound. 2004;32:425-8 pubmed
    Splenic hamartoma is a rare benign tumor of the spleen. It is usually found incidentally at autopsy or splenectomy. We report a case of splenic hamartoma that was discovered during medical workup for vague upper abdominal pain...
  73. Suárez Peñaranda J, Vieites B, Ramírez Santos A, Fernandez Redondo V, Toribio J, Del Rio E, et al. Clinicopathological and immnuohistochemical findings in a series of folliculosebaceous cystic hamartoma. J Cutan Pathol. 2009;36:251-6 pubmed publisher
    Folliculo-sebaceous cystic hamartoma (FSCH) is an uncommon skin condition presenting as a slow-growing papulo-nodular lesion, in or around the nose...
  74. Brandberg G, Raininko R, Eeg Olofsson O. Hypothalamic hamartoma with gelastic seizures in Swedish children and adolescents. Eur J Paediatr Neurol. 2004;8:35-44 pubmed
    Hypothalamic hamartoma with gelastic seizures (HHGS) is an uncommon, often unrecognized, epileptic syndrome with onset of symptoms during childhood.