cysts

Summary

Summary: Any fluid-filled closed cavity or sac that is lined by an EPITHELIUM. Cysts can be of normal, abnormal, non-neoplastic, or neoplastic tissues.

Top Publications

  1. Mafra C, Carrijo Carvalho L, Chudzinski Tavassi A, Taguchi F, Foronda A, Carvalho F, et al. Antimicrobial action of biguanides on the viability of Acanthamoeba cysts and assessment of cell toxicity. Invest Ophthalmol Vis Sci. 2013;54:6363-72 pubmed publisher
    To assess dose- and concentration-dependent rates of biguanides on the viability of Acanthamoeba cysts isolated from severe ulcerative keratitis, and to correlate cysticidal activites with cytotoxic profiles in corneal and endothelial ..
  2. Petrini S, Minnone G, Coccetti M, Frank C, Aiello C, Cutarelli A, et al. Monocytes and macrophages as biomarkers for the diagnosis of megalencephalic leukoencephalopathy with subcortical cysts. Mol Cell Neurosci. 2013;56:307-21 pubmed publisher
    Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare congenital leukodystrophy characterized by macrocephaly, subcortical cysts and demyelination...
  3. Liu M, Xu Y, Feng Y, Zhai W, Che J, Xia S, et al. Androgen-STAT3 activation may contribute to gender disparity in human simply renal cysts. Int J Clin Exp Pathol. 2013;6:686-94 pubmed
    Simple renal cysts (SRC) are a common urological disease mostly in elderly, however the male-to-female ratio was 2.81...
  4. Nishii T, Tanabe M, Tanaka R, Matsuzawa T, Okudela K, Nozawa A, et al. Unique mutation, accelerated mTOR signaling and angiogenesis in the pulmonary cysts of Birt-Hogg-Dubé syndrome. Pathol Int. 2013;63:45-55 pubmed publisher
    ..syndrome (BHD) is an autosomal dominant disorder characterized by fibrofolliculomas, renal tumors and pulmonary cysts with repeated pneumothorax. This disorder is caused by mutations in the gene that encodes folliculin (FLCN)...
  5. Liu S, Zhang M, Qu Y, Pan Y, Zhang Y. Increased iodine uptake in the Nabothian cyst. Clin Nucl Med. 2013;38:157-8 pubmed publisher
    ..The subsequent ultrasound examination demonstrated that the site of elevated iodine activity was caused by cervical Nabothian cyst...
  6. Katano K, Kakuchi Y, Nakashima A, Takahashi S, Kawano M. Efficacy of diffusion-weighted magnetic resonance imaging in detecting infected cysts in a case of polycystic kidney disease. Clin Nephrol. 2011;75 Suppl 1:24-6 pubmed
    ..In many cases, drainage of infected cysts is necessary, although accurate detection of infected cysts from among the numerous hepatic or renal cysts present ..
  7. Priest J, Williams G, Hill D, Dehner L, Jaffe A. Pulmonary cysts in early childhood and the risk of malignancy. Pediatr Pulmonol. 2009;44:14-30 pubmed publisher
    Surgery for congenital and early childhood lung cysts is often dictated by symptoms such as respiratory distress, infection or pneumothorax...
  8. Caroli A, Antiga L, Cafaro M, Fasolini G, Remuzzi A, Remuzzi G, et al. Reducing polycystic liver volume in ADPKD: effects of somatostatin analogue octreotide. Clin J Am Soc Nephrol. 2010;5:783-9 pubmed publisher
    ..Octreotide therapy reduces liver volumes in patients with ADPKD and is safe. ..
  9. Takakura A, Contrino L, Zhou X, Bonventre J, Sun Y, Humphreys B, et al. Renal injury is a third hit promoting rapid development of adult polycystic kidney disease. Hum Mol Genet. 2009;18:2523-31 pubmed publisher
    ..An explanation for the delayed appearance of cysts is the requirement for an additional independent factor, or 'third hit'...

More Information

Publications94

  1. Salahshourifar I, Halim A, Sulaiman W, Ariffin R, Naili Muhamad Nor N, Zilfalil B. De novo interstitial deletion of 1q32.2-q32.3 including the entire IRF6 gene in a patient with oral cleft and other dysmorphic features. Cytogenet Genome Res. 2011;134:83-7 pubmed publisher
    ..The extent of the deletion and the genotype-phenotype correlation are 2 crucial issues...
  2. Monteagudo B, Labandeira J, Cabanillas M, Acevedo A, León Muíños E, Toribio J. Prevalence of milia and palatal and gingival cysts in Spanish newborns. Pediatr Dermatol. 2012;29:301-5 pubmed publisher
    ..in the health area of Ferrol (in northwest Spain) to assess the prevalence and most-frequent locations of oral cysts and milia and to study the influence of different maternal and neonatal parameters in the development of these ..
  3. Yilmaz Z, Deeren A, De Sutter N, Viaene N. Species of Heterodera cysts in cereal fields in Flanders. Commun Agric Appl Biol Sci. 2009;74:581-5 pubmed
    Heterodera is a genus of cyst-forming nematodes, including the cereal cysts which can provoke yield reductions in grain crops...
  4. Lee M, Kim E, Kwak J, Kim M. Partially cystic thyroid nodules on ultrasound: probability of malignancy and sonographic differentiation. Thyroid. 2009;19:341-6 pubmed publisher
    ..The object of this study was to evaluate the frequency of malignancy in mixed echoic thyroid nodules and ascertain the ultrasound findings that help distinguish benign from malignant nodules...
  5. Gaujoux S, Kingham T, Jarnagin W, D Angelica M, Allen P, Fong Y. Single-incision laparoscopic liver resection. Surg Endosc. 2011;25:1489-94 pubmed publisher
    ..Additional experiences are mandatory to assess the viability of this emerging technique and to expand its application to additional right liver resections. ..
  6. Wang J, Shang J, Wu Y, Gu Q, Xiong H, Ding C, et al. Identification of novel MLC1 mutations in Chinese patients with megalencephalic leukoencephalopathy with subcortical cysts (MLC). J Hum Genet. 2011;56:138-42 pubmed publisher
    Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is an autosomal, recessively inherited disease caused by mutations in the MLC1 gene...
  7. Shibao K, Higure A, Yamaguchi K. Case report: laparoendoscopic single-site fenestration of giant hepatic cyst. Surg Technol Int. 2010;20:133-6 pubmed
    ..The LESS surgery has been successfully applied to liver fenestration as an available alternative to conventional laparoscopic fenestration. This method is technically feasible and results in superior cosmesis. ..
  8. Haroon F, Händel U, Angenstein F, Goldschmidt J, Kreutzmann P, Lison H, et al. Toxoplasma gondii actively inhibits neuronal function in chronically infected mice. PLoS ONE. 2012;7:e35516 pubmed publisher
    ..Under the pressure of the immune response, tachyzoites convert into slow-replicating bradyzoites, which persist as cysts in neurons. Currently, it is unclear whether T...
  9. Lim H, Cho J, Kim S. Sclerotherapy of peritoneal inclusion cysts: a long-term evaluation study. Abdom Imaging. 2010;35:431-6 pubmed publisher
    ..This study was designed to evaluate the long-term results of sclerotherapy for the treatment of peritoneal inclusion cysts (PICs). Twenty-nine patients with 30 PICs were included in the study...
  10. Kleinschmidt Demasters B, Cummings T, Hulette C, Morgenlander J, Corboy J. Adult cases of leukoencephalopathy, cerebral calcifications, and cysts: expanding the spectrum of the disorder. J Neuropathol Exp Neurol. 2009;68:432-9 pubmed publisher
    Leukoencephalopathy with cerebral calcifications and cysts (LCC) was first reported in children who developed cognitive decline and variable extrapyramidal, cerebellar, and pyramidal signs, with or without seizures...
  11. Donati M, Stavrou G, Wellmann A, Flemming P, Donati A, Oldhafer K. Laparoscopic deroofing of hepatic cysts: The most effective treatment option. Clin Ter. 2010;161:345-8 pubmed
    ..deroofing has gained wide acceptance in the surgical community to treat symptomatic non-parasitic hepatic cysts. Published non-surgical data still favour aspiration and sclerotherapy as treatment in these cases, though ..
  12. van der Knaap M, Boor I, Estévez R. Megalencephalic leukoencephalopathy with subcortical cysts: chronic white matter oedema due to a defect in brain ion and water homoeostasis. Lancet Neurol. 2012;11:973-85 pubmed publisher
    Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is characterised by chronic white matter oedema...
  13. Grant L, Babar J, Griffin N. Cysts, cavities, and honeycombing in multisystem disorders: differential diagnosis and findings on thin-section CT. Clin Radiol. 2009;64:439-48 pubmed publisher
    Pulmonary cysts, cavities, and honeycombing are seen in a number of systemic disorders...
  14. Janssen M, Waanders E, Te Morsche R, Xing R, Dijkman H, Woudenberg J, et al. Secondary, somatic mutations might promote cyst formation in patients with autosomal dominant polycystic liver disease. Gastroenterology. 2011;141:2056-2063.e2 pubmed publisher
    ..Tissue sections from 71 cysts (2-14 per patient) were obtained for hepatocystin staining and mutation analysis...
  15. Bartel C, Schönkypl S, Walter I. Pseudo-placentational endometrial cysts in a bitch. Anat Histol Embryol. 2010;39:74-80 pubmed publisher
    ..Even without clinical evidence, reduction of the uterine lumen by cysts implicates disturbances during migration, nidation and development of the embryo...
  16. van der Knaap M, Lai V, Kohler W, Salih M, Fonseca M, Benke T, et al. Megalencephalic leukoencephalopathy with cysts without MLC1 defect. Ann Neurol. 2010;67:834-7 pubmed publisher
    Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is an autosomal recessive disease characterized by early infantile macrocephaly and delayed motor and cognitive deterioration...
  17. Kunogi M, Kurihara M, Ikegami T, Kobayashi T, Shindo N, Kumasaka T, et al. Clinical and genetic spectrum of Birt-Hogg-Dube syndrome patients in whom pneumothorax and/or multiple lung cysts are the presenting feature. J Med Genet. 2010;47:281-7 pubmed publisher
    ..inherited autosomal genodermatosis characterised by fibrofolliculomas of the skin, renal tumours and multiple lung cysts. Genetic studies have disclosed that the clinical picture as well as responsible germline FLCN mutations are ..
  18. Sreenarasimhaiah J, Lara L, Jazrawi S, Barnett C, Tang S. A comparative analysis of pancreas cyst fluid CEA and histology with DNA mutational analysis in the detection of mucin producing or malignant cysts. JOP. 2009;10:163-8 pubmed
    The main objective of pancreatic cyst fluid analysis is to differentiate mucin-producing or malignant cysts from other cysts which have a benign course...
  19. Koga S, Furuya M, Takahashi Y, Tanaka R, Yamaguchi A, Yasufuku K, et al. Lung cysts in Birt-Hogg-Dubé syndrome: histopathological characteristics and aberrant sequence repeats. Pathol Int. 2009;59:720-8 pubmed publisher
    ..The affected patients are predisposed to cutaneous fibrofolliculomas, renal cell tumors and lung cysts with recurrent pneumothorax...
  20. Choi N, Rha S, Jung S, Choi B, Oh S, Byun J, et al. Ruptured endometrial cysts as a rare cause of acute pelvic pain: can we differentiate them from ruptured corpus luteal cysts on CT scan?. J Comput Assist Tomogr. 2011;35:454-8 pubmed publisher
    To evaluate the usefulness of CT in the differentiation of ruptured endometrial cysts and corpus luteal cysts.
  21. Leung G. Abdominal cerebrospinal fluid (CSF) pseudocyst presented with inferior vena caval obstruction and hydronephrosis. Childs Nerv Syst. 2010;26:1243-5 pubmed publisher
    ..A large pseudocyst may exert a significant pressure effect, but vascular or urological symptoms are extremely rare. We report an unusual case of a CSF pseudocyst causing inferior vena caval and ureteric obstruction...
  22. Polvi A, Linnankivi T, Kivela T, Herva R, Keating J, Makitie O, et al. Mutations in CTC1, encoding the CTS telomere maintenance complex component 1, cause cerebroretinal microangiopathy with calcifications and cysts. Am J Hum Genet. 2012;90:540-9 pubmed publisher
    Cerebroretinal microangiopathy with calcifications and cysts (CRMCC) is a rare multisystem disorder characterized by extensive intracranial calcifications and cysts, leukoencephalopathy, and retinal vascular abnormalities...
  23. Larsson A, Crang Svalenius E, Dykes A. Information for better or for worse: interviews with parents when their foetus was found to have choroid plexus cysts at a routine second trimester ultrasound. J Psychosom Obstet Gynaecol. 2009;30:48-57 pubmed publisher
    ..of parents' experiences and handling of the situation, when their foetus was diagnosed as having choroid plexus cysts, at a routine second trimester ultrasound examination...
  24. Martins R, Santana M, Tavares E. Vocal cysts: clinical, endoscopic, and surgical aspects. J Voice. 2011;25:107-10 pubmed publisher
    Vocal cysts are benign laryngeal lesions, which affect children and adults. They can be classified as epidermic or mucous-retention cyst. The objective was to study the clinical, endoscopic, and surgical aspects of vocal cysts...
  25. Aussilhou B, Douflé G, Hubert C, Francoz C, Paugam C, Paradis V, et al. Extended liver resection for polycystic liver disease can challenge liver transplantation. Ann Surg. 2010;252:735-43 pubmed publisher
  26. Drenth J, Chrispijn M, Nagorney D, Kamath P, Torres V. Medical and surgical treatment options for polycystic liver disease. Hepatology. 2010;52:2223-30 pubmed publisher
  27. Gin E, Tanaka E, Brusch L. A model for cyst lumen expansion and size regulation via fluid secretion. J Theor Biol. 2010;264:1077-88 pubmed publisher
    Many internal epithelial organs derive from cysts, which are tissues comprised of bent epithelial cell layers enclosing a lumen. Ion accumulation in the lumen drives water influx and consequently water accumulation and cyst expansion...
  28. Malik S, Kakar N, Hasnain S, Ahmad J, Wilcox E, Naz S. Epidemiology of Van der Woude syndrome from mutational analyses in affected patients from Pakistan. Clin Genet. 2010;78:247-56 pubmed publisher
    ..This is the first study of VWS in Pakistan and we estimate that 1 in 100 patients with CL with or without CP (CL/P) are affected in the Pakistani population predominantly from the Punjab area...
  29. Monama G, Tshifularo M. Intralesional bleomycin injections in the treatment of benign lymphoepithelial cysts of the parotid gland in HIV-positive patients: case reports. Laryngoscope. 2010;120:243-6 pubmed publisher
    Benign lymphoepithelial cysts (BLCs) of the parotid gland are associated with human immunodeficiency virus. These cysts may grow large and uncomfortable, causing significant cosmetic embarrassment for the patient...
  30. Matsuzawa N, Kondo S, Shimozato K, Nagao T, Nakano M, Tsuda M, et al. Two missense mutations of the IRF6 gene in two Japanese families with popliteal pterygium syndrome. Am J Med Genet A. 2010;152A:2262-7 pubmed publisher
    ..This finding suggests that the C-terminus region of IRF6 could have an important function in phosphorylation or protein interaction. To our knowledge, this is the first report of mutations observed in Japanese PPS patients...
  31. Lee J, Park C, Kim K, Lee C, Choi J, Shin B, et al. Cystic lesions of the gastrointestinal tract: multimodality imaging with pathologic correlations. Korean J Radiol. 2010;11:457-68 pubmed publisher
  32. Duarri A, López de Heredia M, Capdevila Nortes X, Ridder M, Montolio M, López Hernández T, et al. Knockdown of MLC1 in primary astrocytes causes cell vacuolation: a MLC disease cell model. Neurobiol Dis. 2011;43:228-38 pubmed publisher
    Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare type of leukodystrophy, in the majority of cases caused by mutations in the MLC1 gene...
  33. Dencker M, Jexmark T, Hansen F, Tydén P, Roijer A, Lührs C. Bileaflet blood cysts on the mitral valve in an adult. J Am Soc Echocardiogr. 2009;22:1085.e5-8 pubmed publisher
    Blood cysts within the heart are very rare entities in adults. The authors present possibly the first ever case in which blood cysts were found on both mitral valve leaflets...
  34. Smorgick N, Herman A, Schneider D, Halperin R, Pansky M. Paraovarian cysts of neoplastic origin are underreported. JSLS. 2009;13:22-6 pubmed
    We suspected that paraovarian cysts of neoplastic origin may be underreported...
  35. Onur M, Bakal U, Kocakoc E, Tartar T, Kazez A. Cystic abdominal masses in children: a pictorial essay. Clin Imaging. 2013;37:18-27 pubmed publisher
    ..In this pictorial essay, we summarized the imaging features of common cystic abdominal masses of children, including cystic lesions arising from liver, biliary ducts, kidney, pancreas, bowel, ovary, mesentery, and miscellaneous tissues...
  36. Veigel M, Prescott Focht J, Rodriguez M, Zinati R, Shao L, Moore C, et al. Fibropolycystic liver disease in children. Pediatr Radiol. 2009;39:317-27; quiz 420-1 pubmed publisher
    ..include congenital hepatic fibrosis, biliary hamartomas, autosomal dominant polycystic liver disease, choledochal cysts and Caroli disease...
  37. Sendt W, Weber T, Retschke S, Altendorf Hofmann A. [Symptomatic non-parasitic liver cysts: early and long-term results of surgical management]. Zentralbl Chir. 2009;134:149-54 pubmed publisher
    Symptomatic congenital cysts of the liver, whether solitary or multiple in appearance, can be treated by a laparoscopic approach. Here we present our single centre experience encompassing a rather large cohort of patients.
  38. Engelberg J, Datta A, Mostov K, Hunt C. MDCK cystogenesis driven by cell stabilization within computational analogues. PLoS Comput Biol. 2011;7:e1002030 pubmed publisher
    ..Reducing the amount of in silico luminal cell death had limited effect on cystogenesis. Simulations provide an observable theory for cystogenesis based on hypothesized, cell-level operating principles...
  39. Song X, Di Giovanni V, He N, Wang K, Ingram A, Rosenblum N, et al. Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks. Hum Mol Genet. 2009;18:2328-43 pubmed publisher
    To elucidate the molecular pathways that modulate renal cyst growth in ADPKD, we performed global gene profiling on cysts of different size (<1 ml, n = 5; 10-20 ml, n = 5; >50 ml, n = 3) and minimally cystic tissue (MCT, n = 5) ..
  40. Khoury T, Rivera L. Foregut duplication cysts: a report of two cases with emphasis on embryogenesis. World J Gastroenterol. 2011;17:130-4 pubmed publisher
    ..We describe two cases of these cysts, with emphasis on their immunophenotype and embryogenesis...
  41. Lee J, Park M, Kim H. A case of epithelial inclusion cyst of iris. Korean J Ophthalmol. 2008;22:259-62 pubmed publisher
    ..There was no recurrence as determined by slit lamp examination up to 6 months after treatment. Needle aspiration and Ab externo laser photocoagulation can be used to effectively treat epithelial inclusion cysts of the iris.
  42. Brignone M, Lanciotti A, Macioce P, Macchia G, Gaetani M, Aloisi F, et al. The beta1 subunit of the Na,K-ATPase pump interacts with megalencephalic leucoencephalopathy with subcortical cysts protein 1 (MLC1) in brain astrocytes: new insights into MLC pathogenesis. Hum Mol Genet. 2011;20:90-103 pubmed publisher
    Megalencephalic leucoencephalopathy with subcortical cysts (MLC) is a rare congenital leucodystrophy caused by mutations in MLC1, a membrane protein of unknown function...
  43. Miller M, Barr B, Nordhausen R, James E, Magargal S, Murray M, et al. Ultrastructural and molecular confirmation of the development of Sarcocystis neurona tissue cysts in the central nervous system of southern sea otters (Enhydra lutris nereis). Int J Parasitol. 2009;39:1363-72 pubmed publisher
    ..Schizonts, free merozoites and tissue cysts were observed in the brains of all three infected animals...
  44. Janssen M, Waanders E, Woudenberg J, Lefeber D, Drenth J. Congenital disorders of glycosylation in hepatology: the example of polycystic liver disease. J Hepatol. 2010;52:432-40 pubmed publisher
    ..PCLD) is a rare progressive disorder characterized by an increased liver volume due to many (>20) fluid-filled cysts of biliary origin...
  45. Mayerhoefer M, Schima W, Trattnig S, Pinker K, Berger Kulemann V, Ba Ssalamah A. Texture-based classification of focal liver lesions on MRI at 3.0 Tesla: a feasibility study in cysts and hemangiomas. J Magn Reson Imaging. 2010;32:352-9 pubmed publisher
    To determine the feasibility of texture analysis for the classification of liver cysts and hemangiomas, on nonenhanced, zero-fill interpolated T1- and T2-weighted MR images.
  46. Seo J, Kim S, Lee S, Park J, Woo S, Jeong J, et al. Appropriate diagnosis of biliary cystic tumors: comparison with atypical hepatic simple cysts. Eur J Gastroenterol Hepatol. 2010;22:989-96 pubmed publisher
    ..Biliary cystadenoma (BCA) and biliary cystadenocarcinoma (BCAC) are often confused with other intrahepatic cystic diseases...
  47. Muchatuta M, Gattone V, Witzmann F, Blazer Yost B. Structural and functional analyses of liver cysts from the BALB/c-cpk mouse model of polycystic kidney disease. Exp Biol Med (Maywood). 2009;234:17-27 pubmed publisher
    Liver cysts arising from hepatic bile ducts are a common extra-renal pathology associated with both autosomal dominant and recessive polycystic kidney disease in humans...
  48. Mazza O, Fernandez D, Pekolj J, Pfaffen G, Sánchez Clariá R, Molmenti E, et al. Management of nonparasitic hepatic cysts. J Am Coll Surg. 2009;209:733-9 pubmed publisher
    The optimal management of nonparasitic hepatic cysts (NPHC) is a topic of debate. The purpose of this study was to evaluate our 17-year experience with NPHC.
  49. Chew W, Segarra I, Ambu S, Mak J. Significant reduction of brain cysts caused by Toxoplasma gondii after treatment with spiramycin coadministered with metronidazole in a mouse model of chronic toxoplasmosis. Antimicrob Agents Chemother. 2012;56:1762-8 pubmed publisher
    Toxoplasma gondii is a parasite that generates latent cysts in the brain; reactivation of these cysts may lead to fatal toxoplasmic encephalitis, for which treatment remains unsuccessful...
  50. Hong Y, Onal B, Diamond D, Retik A, Cendron M, Nguyen H. Robot-assisted laparoscopic excision of symptomatic retrovesical cysts in boys and young adults. J Urol. 2011;186:2372-8 pubmed publisher
    ..We review our surgical experience with the management of retrovesical cystic anomalies using robot-assisted laparoscopic techniques...
  51. Kendrick M, Nagorney D. Bile duct cysts: contemporary surgical management. Curr Opin Gastroenterol. 2009;25:240-4 pubmed
    Surgical treatment of bile duct cysts remains the mainstay to reduce cyst-related complications and risk of malignancy...
  52. López Hernández T, Ridder M, Montolio M, Capdevila Nortes X, Polder E, Sirisi S, et al. Mutant GlialCAM causes megalencephalic leukoencephalopathy with subcortical cysts, benign familial macrocephaly, and macrocephaly with retardation and autism. Am J Hum Genet. 2011;88:422-32 pubmed publisher
    Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a leukodystrophy characterized by early-onset macrocephaly and delayed-onset neurological deterioration...
  53. Fedeles S, Tian X, Gallagher A, Mitobe M, Nishio S, Lee S, et al. A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation. Nat Genet. 2011;43:639-47 pubmed publisher
  54. Granholm C, Olsson Bergland K, Walhjalt H, Magnusson B. Oral mucoceles; extravasation cysts and retention cysts. A study of 298 cases. Swed Dent J. 2009;33:125-30 pubmed
    Oral mucoceles can be divided in two different forms, extravasation and retention cysts. The aim of this study was to identify the frequency of each form, sex- and age distribution, location, recurrences, referent and the differences ..
  55. López Hernández T, Sirisi S, Capdevila Nortes X, Montolio M, Fernández Dueñas V, Scheper G, et al. Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts. Hum Mol Genet. 2011;20:3266-77 pubmed publisher
    Megalencephalic leukoencephalopathy with subcortical cysts (MLC) is a rare leukodystrophy caused by mutations in MLC1 or GLIALCAM. The GLIALCAM gene product functions as an MLC1 beta-subunit...
  56. Choi H, Lee J, Lee K, Lee K, Rhee J, Kim K, et al. Differential diagnosis for intrahepatic biliary cystadenoma and hepatic simple cyst: significance of cystic fluid analysis and radiologic findings. J Clin Gastroenterol. 2010;44:289-93 pubmed publisher
    This study evaluated the significance of cystic fluid analysis and radiologic findings in the differential diagnosis of biliary cystadenomas (BCA) and hepatic simple cysts (HSCs).
  57. Adas G, Karatepe O, Altiok M, Battal M, Bender O, Ozcan D, et al. Diagnostic problems with parasitic and non-parasitic splenic cysts. BMC Surg. 2009;9:9 pubmed publisher
    The splenic cysts constitute a very rare clinical entity. They may occur secondary to trauma or even being more seldom due to parasitic infestations, mainly caused by ecchinocccus granulosus...
  58. Gatta G, Parlato V, Di Grezia G, Porto A, Cappabianca S, Grassi R, et al. Ultrasound-guided aspiration and ethanol sclerotherapy for treating endometrial cysts. Radiol Med. 2010;115:1330-9 pubmed publisher
    The authors sought to evaluate the effectiveness of ultrasound (US)-guided aspiration and ethanol sclerotherapy in treating endometrial cysts and adopt this procedure as an alternative to surgery.
  59. Kim J, Bae S, Sung M, Lee K, Park S. Comparative proteomic analysis of trophozoites versus cysts of Giardia lamblia. Parasitol Res. 2009;104:475-9 pubmed publisher
    ..Protein spots that increased in the extracts of cysts compared to trophozoites were identified by MALDI-TOF mass spectroscopy and categorized as cytoskeletal proteins, ..
  60. Buchholz B, Teschemacher B, Schley G, Schillers H, Eckardt K. Formation of cysts by principal-like MDCK cells depends on the synergy of cAMP- and ATP-mediated fluid secretion. J Mol Med (Berl). 2011;89:251-61 pubmed publisher
    It has been suggested that more than 70% of the renal cysts in patients with autosomal dominant polycystic kidney disease (ADPKD) arise from the collecting duct and that within this segment cysts originate almost exclusively from ..
  61. Verma S. Canal-like median raphe cysts: an unusual presentation of an unusual condition. Clin Exp Dermatol. 2009;34:e857-8 pubmed publisher
    Median raphe cysts are an uncommon dermatology. Even more uncommon is their presentation as a cordlike or canaliform induration in the median raphe, confusingly called a median raphe cyst...
  62. Ishii H, Oka H, Amemiya Y, Iwata A, Otani S, Kishi K, et al. A Japanese family with multiple lung cysts and recurrent pneumothorax: a possibility of Birt-Hogg-Dubé syndrome. Intern Med. 2009;48:1413-7 pubmed
    ..A chest CT showed multiple lung cysts, and breast cancer was simultaneously detected that needed priority surgical treatment...
  63. Menko F, van Steensel M, Giraud S, Friis Hansen L, Richard S, Ungari S, et al. Birt-Hogg-Dubé syndrome: diagnosis and management. Lancet Oncol. 2009;10:1199-206 pubmed publisher
    ..syndrome (BHD) is an autosomal dominant condition characterised clinically by skin fibrofolliculomas, pulmonary cysts, spontaneous pneumothorax, and renal cancer...
  64. Marom T, Russo E, Ben Salem D, Roth Y. Nasopharyngeal cysts. Int J Pediatr Otorhinolaryngol. 2009;73:1063-70 pubmed publisher
    Nasopharyngeal cysts are uncommon, and are mostly asymptomatic. However, these lesions are infrequently found during routine endoscopies and imaging studies...
  65. Kim J, Kim S, Eun H, Lee M, Lee J, Han J, et al. Differentiation between biliary cystic neoplasms and simple cysts of the liver: accuracy of CT. AJR Am J Roentgenol. 2010;195:1142-8 pubmed publisher
    ..was to determine significant CT findings for the differentiation of biliary cystic neoplasms from simple hepatic cysts and to assess whether radiologists' performance for the differentiation is improved with the knowledge of ..
  66. Gonik N, Smith L. Radiofrequency ablation of pediatric vallecular cysts. Int J Pediatr Otorhinolaryngol. 2012;76:1819-22 pubmed publisher
    Pediatric congenital vallecular cysts are an infrequent cause of infantile airway obstruction that can cause difficulty breathing or feeding, and lead to failure to thrive or death...
  67. Capan M, Keltner S, Thalhammer F, Winkler S, Jäger W, Zeitlinger M, et al. Intra-cystic drug concentration of albendazole sulphoxide in patients with Echinococcus granulosus cysts. Am J Trop Med Hyg. 2009;81:712-3 pubmed publisher
    ..However, only limited data are available on target site concentrations in liver cysts and data for non-liver cysts are lacking...
  68. Al Jabri T, Misra S, Maan Z, Khan K, Coker C, Thompson P. Ultrasonography of simple intratesticular cysts: a 13 year experience in a single centre. Diagn Pathol. 2011;6:24 pubmed publisher
    Simple intratesticular cysts are being reported more commonly due to the wider use of scrotal ultrasonography however, their management remains unclear...
  69. Takahashi G, Yoshida H, Mamada Y, Taniai N, Bando K, Tajiri T. Intracystic hemorrhage of a large simple hepatic cyst. J Nippon Med Sch. 2008;75:302-5 pubmed
    Spontaneous intracystic hemorrhage rarely occurs in nonparasitic hepatic cysts. We describe a patient with spontaneous intracystic hemorrhage of a large simple hepatic cyst that mimicked a malignancy...
  70. Zafar I, Ravichandran K, Belibi F, Doctor R, Edelstein C. Sirolimus attenuates disease progression in an orthologous mouse model of human autosomal dominant polycystic kidney disease. Kidney Int. 2010;78:754-61 pubmed publisher
    ..Western blot analysis of whole kidney lysates and immunohistochemistry of the cysts found that phospho-S6 ribosomal protein, a marker of mTORC1 activity, was increased in Pkd2WS25/- mice and its ..
  71. Goodrich Z, Wilke V, Root Kustritz M. Two cases of paraprostatic cysts in castrated male dogs. J Am Anim Hosp Assoc. 2011;47:e195-8 pubmed publisher
    ..Paraprostatic cysts were diagnosed in both cases based on the results of abdominal ultrasonography, MRI, and histopathology of tissue ..
  72. Lee L, Sheu B, Chou L, Huang S, Chang D, Chang W. An easy new approach to the laparoscopic treatment of large adnexal cysts. Minim Invasive Ther Allied Technol. 2011;20:150-4 pubmed publisher
    We describe a technique for laparoscopically assisted extracorporeal cystectomy or adnexectomy of large adnexal cysts without spillage of the cyst contents...
  73. Rogart J, Loren D, Singu B, Kowalski T. Cyst wall puncture and aspiration during EUS-guided fine needle aspiration may increase the diagnostic yield of mucinous cysts of the pancreas. J Clin Gastroenterol. 2011;45:164-9 pubmed publisher
    Pancreatic cysts are common, however, their diagnosis and classification remains a challenge despite advances in cross-sectional imaging and endoscopic ultrasound with fine needle aspiration (EUS-FNA).
  74. Jusufovic R, Zerem E. Percutaneous treatment of symptomatic non-parasitic benign liver cysts with 20% NaCl solution. Med Arh. 2011;65:35-7 pubmed
    The aim of the study is to evaluate efficacy of single-session 20% NaCl solution sclerotherapy in the treatment of symptomatic nonparasitic benign liver cysts.
  75. Waanders E, van Keimpema L, Brouwer J, van Oijen M, Aerts R, Sweep F, et al. Carbohydrate antigen 19-9 is extremely elevated in polycystic liver disease. Liver Int. 2009;29:1389-95 pubmed publisher
    ..We examined the value of CA19-9 measurement in polycystic livers after observing high CA19-9 cyst fluid levels in a benign polycystic liver case...
  76. Bulut E, Sahin B, Muglali M, Bekcioglu B. Comparison of the planimetry and point-counting methods for the assessment of the size of the mandible cysts on orthopantomograms. Med Oral Patol Oral Cir Bucal. 2012;17:e442-6 pubmed
    The purpose of this study is to compare the computer-assisted planimetry and point-counting methods in evaluating the sizes of the mandibular cysts with respect to their agreement and the time required to analyze.
  77. Vajda P, Kereskai L, Czauderna P, Schaarschmidt K, Kálmán A, Koltai J, et al. Re-evaluation of histological findings of nonparasitic splenic cysts. Eur J Gastroenterol Hepatol. 2012;24:316-9 pubmed publisher
    The pathogenesis of nonparasitic splenic cysts (NPSCs) has not been clarified completely. The aim of this multinational and multicentre retrospective study was to further elucidate the origin of NPSCs.
  78. Ryu D, Oh T. Laparoscopic decortication of large renal cysts: a comparison between the transperitoneal and retroperitoneal approaches. J Laparoendosc Adv Surg Tech A. 2009;19:629-32 pubmed publisher
    We compared the operative outcomes and follow-up results of laparoscopic decortication of large, simple renal cysts, performed by the transperitoneal (TP) and retroperitoneal (RP) approaches, and identified selection criteria for each ..
  79. Berg E, Moore C. Office-based sclerotherapy for benign parotid lymphoepithelial cysts in the HIV-positive patient. Laryngoscope. 2009;119:868-70 pubmed publisher
    To determine the efficacy of sodium morrhuate injection therapy in the control of benign lymphoepithelial cysts of the parotid gland.
  80. deSouza R, Prachalias A, Srinivasan P, O Doherty M, Olsburgh J. Differentiation between infection in kidney and liver cysts in autosomal dominant polycystic kidney disease: use of PET-CT in diagnosis and to guide management. Transplant Proc. 2009;41:1942-5 pubmed publisher
    ..polycystic kidney disease in which PET-CT was used to differentiate between infection in the kidney and liver cysts. Localization of infection to the liver rather than to kidney cysts altered patient management...
  81. Mahamed D, Mills J, Egan C, Denkers E, Bynoe M. CD73-generated adenosine facilitates Toxoplasma gondii differentiation to long-lived tissue cysts in the central nervous system. Proc Natl Acad Sci U S A. 2012;109:16312-7 pubmed publisher
    ..transformation from a rapidly dividing tachyzoite to a long-lived, slow-dividing bradyzoite contained within cysts. The role of extracellular adenosine in T. gondii pathogenesis has not been previously investigated. T...
  82. Zhang Y, Yuan L, Shen F, Wang Y. Hemorrhagic hepatic cysts mimicking biliary cystadenoma. World J Gastroenterol. 2009;15:4601-3 pubmed
    ..Here we present two cases of huge hemorrhagic simple hepatic cysts. Case 1 was a 43-year-old man with a cystic lesion measuring 13 cm x 12 cm in the right hepatic lobe...
  83. Al Holou W, Terman S, Kilburg C, Garton H, Muraszko K, Chandler W, et al. Prevalence and natural history of pineal cysts in adults. J Neurosurg. 2011;115:1106-14 pubmed publisher
    We reviewed our experience with pineal cysts to define the natural history and clinical relevance of this common intracranial finding.
  84. Kim D, Lee E, In H, Kim S. Sonographic differentiation of partially cystic thyroid nodules: a prospective study. AJNR Am J Neuroradiol. 2010;31:1961-6 pubmed publisher
    ..There is no prospective study related to the sonographic differentiation of malignant PCTN from benign PCTN. This prospective study was designed to evaluate differentiation of benign from malignant PCTNs with thyroid sonography...
  85. Matsumoto M, Watanabe K, Tsuji T, Ishii K, Takaishi H, Nakamura M, et al. Microendoscopic resection of lumbar discal cysts. Minim Invasive Neurosurg. 2010;53:69-73 pubmed publisher
    ..Surgical resection of the cyst is the reported treatment of choice. In this study, the authors report the minimally invasive surgical resection of lumbar discal cysts using a microendoscopy.