visceral pain


Summary: Pain originating from internal organs (VISCERA) associated with autonomic phenomena (PALLOR; SWEATING; NAUSEA; and VOMITING). It often becomes a REFERRED PAIN.

Top Publications

  1. Linnman C. New pieces for the substance P puzzle. Pain. 2013;154:966-7 pubmed publisher
  2. Balemans D, Boeckxstaens G, Talavera K, Wouters M. Transient receptor potential ion channel function in sensory transduction and cellular signaling cascades underlying visceral hypersensitivity. Am J Physiol Gastrointest Liver Physiol. 2017;312:G635-G648 pubmed publisher
    ..We propose that a better understanding of TRP channels and their modulators may facilitate the development of more selective and effective therapies to treat visceral hypersensitivity. ..
  3. Ding S, Zhu L, Tian Y, Zhu T, Huang X, Zhang X. P2X3 receptor involvement in endometriosis pain via ERK signaling pathway. PLoS ONE. 2017;12:e0184647 pubmed publisher
    ..P2X ligand-gated ion channel 3 (P2X3) is crucially involved in peripheral nociceptive processes of somatic and visceral pain. Endometriosis pain is considered as a kind of inflammatory and neuropathic pain...
  4. Mao Y, Li Z, Chen K, Yu H, Zhang S, Jiang M, et al. Antinociceptive Effect of Ghrelin in a Rat Model of Irritable Bowel Syndrome Involves TRPV1/Opioid Systems. Cell Physiol Biochem. 2017;43:518-530 pubmed publisher
    ..The results indicate that ghrelin exerted an antinociceptive effect, which was mediated via TRPV1/opioid systems, in IBS-induced visceral hypersensitivity. Ghrelin might potentially be used as a new treatment for IBS. ..