Summary: The scientific discipline concerned with the physiology of the nervous system.

Top Publications

  1. Moseley L. Unraveling the barriers to reconceptualization of the problem in chronic pain: the actual and perceived ability of patients and health professionals to understand the neurophysiology. J Pain. 2003;4:184-9 pubmed
    ..whether (1) health professionals and patients can understand currently accurate information about the neurophysiology of pain and (2) health professionals accurately estimate the ability of patients to understand the ..
  2. Takakusaki K. Neurophysiology of gait: from the spinal cord to the frontal lobe. Mov Disord. 2013;28:1483-91 pubmed publisher
    ..These processes enable the corticospinal system to generate limb trajectory and achieve accurate foot placement. Loops from the motor cortical areas to the basal ganglia and the cerebellum can serve this purpose. ..
  3. Sensi S, Paoletti P, Koh J, Aizenman E, Bush A, Hershfinkel M. The neurophysiology and pathology of brain zinc. J Neurosci. 2011;31:16076-85 pubmed publisher
  4. Dionigi G, Chiang F, Rausei S, Wu C, Boni L, Lee K, et al. Surgical anatomy and neurophysiology of the vagus nerve (VN) for standardised intraoperative neuromonitoring (IONM) of the inferior laryngeal nerve (ILN) during thyroidectomy. Langenbecks Arch Surg. 2010;395:893-9 pubmed publisher
    ..approaches, are the topographic relationship of the VN with the carotid and jugular vessels as well as the neurophysiology of the VN and ILN that have been studied, with a prospective approach, in patients with various thyroid ..
  5. Gao D, Vasconcelos N. Decision-theoretic saliency: computational principles, biological plausibility, and implications for neurophysiology and psychophysics. Neural Comput. 2009;21:239-71 pubmed publisher
    ..In particular, for the class of stimuli studied, it performs the three fundamental operations of statistical inference: assessment of probabilities, implementation of Bayes decision rule, and feature selection. ..
  6. van Eijsden P, Hyder F, Rothman D, Shulman R. Neurophysiology of functional imaging. Neuroimage. 2009;45:1047-54 pubmed publisher
    ..Given the dependence of observable psychological properties upon the "baseline" energy, we believe that it is unnecessarily limiting to define a particular state as the baseline. ..
  7. Lencer R, Trillenberg P. Neurophysiology and neuroanatomy of smooth pursuit in humans. Brain Cogn. 2008;68:219-28 pubmed publisher
    ..Applying this approach to neurological and also mental illness can reveal distinct disturbances within neural networks being present in these disorders and also the impact of medication on this circuitry. ..
  8. Mogdans J, Bleckmann H. Coping with flow: behavior, neurophysiology and modeling of the fish lateral line system. Biol Cybern. 2012;106:627-42 pubmed publisher
    ..Finally, it reports new theoretical and biomimetic approaches to understand lateral line function. ..
  9. Gibbons C, Freeman R, Veves A. Diabetic neuropathy: a cross-sectional study of the relationships among tests of neurophysiology. Diabetes Care. 2010;33:2629-34 pubmed publisher
    ..The natural clustering of both patients and healthy control subjects suggests that variations in the population will need to be considered in future studies of diabetic neuropathy. ..

More Information


  1. Schulte Körne G, Bruder J. Clinical neurophysiology of visual and auditory processing in dyslexia: a review. Clin Neurophysiol. 2010;121:1794-809 pubmed publisher
  2. Nakata H, Yoshie M, Miura A, Kudo K. Characteristics of the athletes' brain: evidence from neurophysiology and neuroimaging. Brain Res Rev. 2010;62:197-211 pubmed publisher
    ..In addition, it is likely that the manner of neuronal modulation differs among sports. We also discuss several problems that should be addressed in future studies. ..
  3. Goldberg D, Victor J, Gardner E, Gardner D. Spike train analysis toolkit: enabling wider application of information-theoretic techniques to neurophysiology. Neuroinformatics. 2009;7:165-78 pubmed publisher , maintained as a resource for the computational neuroscience and neuroinformatics communities. Use cases drawn from somatosensory and gustatory neurophysiology, and community use of STAToolkit, demonstrate its utility and scope.
  4. Johnston K, Everling S. Neurophysiology and neuroanatomy of reflexive and voluntary saccades in non-human primates. Brain Cogn. 2008;68:271-83 pubmed publisher
  5. McDowell J, Dyckman K, Austin B, Clementz B. Neurophysiology and neuroanatomy of reflexive and volitional saccades: evidence from studies of humans. Brain Cogn. 2008;68:255-70 pubmed publisher
  6. Müri R, Nyffeler T. Neurophysiology and neuroanatomy of reflexive and volitional saccades as revealed by lesion studies with neurological patients and transcranial magnetic stimulation (TMS). Brain Cogn. 2008;68:284-92 pubmed publisher
    This review discusses the neurophysiology and neuroanatomy of the cortical control of reflexive and volitional saccades in humans...
  7. Sharpe J. Neurophysiology and neuroanatomy of smooth pursuit: lesion studies. Brain Cogn. 2008;68:241-54 pubmed publisher
    ..The anatomical and physiological bases of defective smooth pursuit are discussed here in the context of the effects of lesion in the human brain. ..
  8. Catley M, O Connell N, Moseley G. How good is the neurophysiology of pain questionnaire? A Rasch analysis of psychometric properties. J Pain. 2013;14:818-27 pubmed publisher
    The Neurophysiology of Pain Questionnaire (NPQ) was devised to assess how an individual conceptualizes the biological mechanisms that underpin his or her pain...
  9. Breen P, Murphy K, Browne G, Molloy F, Reid V, Doherty C, et al. Formative evaluation of a telemedicine model for delivering clinical neurophysiology services part II: the referring clinician and patient perspective. BMC Med Inform Decis Mak. 2010;10:49 pubmed publisher
    ..responded to the first part of a postal survey which examined their satisfaction with traditional clinical neurophysiology services...
  10. Breen P, Murphy K, Browne G, Molloy F, Reid V, Doherty C, et al. Formative evaluation of a telemedicine model for delivering clinical neurophysiology services part I: utility, technical performance and service provider perspective. BMC Med Inform Decis Mak. 2010;10:48 pubmed publisher
    ..Service use, technical performance and satisfaction of clinical neurophysiology personnel were assessed qualitatively and quantitatively...
  11. Chamorro P, Muñiz C, Levi R, Arroyo D, Rodríguez F, Varona P. Generalization of the dynamic clamp concept in neurophysiology and behavior. PLoS ONE. 2012;7:e40887 pubmed publisher other kinds of closed-loop protocols beyond (or in addition to) electrical stimulation and recording in neurophysiology and behavioral studies for neuroethology...
  12. Nir Y, Tononi G. Dreaming and the brain: from phenomenology to neurophysiology. Trends Cogn Sci. 2010;14:88-100 pubmed publisher
    ..In parallel, brain lesion studies, functional imaging and neurophysiology have advanced current knowledge of the neural basis of dreaming...
  13. McAnulty G, Duffy F, Butler S, Parad R, Ringer S, Zurakowski D, et al. Individualized developmental care for a large sample of very preterm infants: health, neurobehaviour and neurophysiology. Acta Paediatr. 2009;98:1920-6 pubmed publisher
    ..The NIDCAP is an effective treatment for very early-born infants. It reduces health morbidities and enhances neurodevelopment, functional competence and life quality for preterm infants at 2 w and 9 mCA. ..
  14. Rothwell J. Overview of neurophysiology of movement control. Clin Neurol Neurosurg. 2012;114:432-5 pubmed publisher
    ..Finally I discuss some of the new methods of stimulating descending motor pathways in humans. ..
  15. Lewi J, Butera R, Paninski L. Sequential optimal design of neurophysiology experiments. Neural Comput. 2009;21:619-87 pubmed publisher
    ..However, application of adaptive methods to neurophysiology has been limited by severe computational challenges...
  16. Ward M, Rajdev P, Ellison C, Irazoqui P. Toward a comparison of microelectrodes for acute and chronic recordings. Brain Res. 2009;1282:183-200 pubmed publisher
  17. Perez Goodwyn P, Katsumata Wada A, Okada K. Morphology and neurophysiology of tarsal vibration receptors in the water strider Aquarius paludum (Heteroptera: Gerridae). J Insect Physiol. 2009;55:855-61 pubmed publisher
    ..In turn, four ventral subapical trichobothria that are in direct contact with the water surface during locomotion, proved to be mechanosensory. The anatomical and ultrastructural observations support these electro-physiological results...
  18. Nir R, Lev R, Moont R, Granovsky Y, Sprecher E, Yarnitsky D. Neurophysiology of the cortical pain network: revisiting the role of S1 in subjective pain perception via standardized low-resolution brain electromagnetic tomography (sLORETA). J Pain. 2008;9:1058-69 pubmed publisher
    ..Although this study cannot support a causal relation between SI activation magnitude and pain perception, such relation might be insinuated. ..
  19. Masakado Y, Kawakami M, Suzuki K, Abe L, Ota T, Kimura A. Clinical neurophysiology in the diagnosis of peroneal nerve palsy. Keio J Med. 2008;57:84-9 pubmed
    ..Therefore the neurophysiologic evaluation must be performed not only for the differential diagnosis, but also for planning the treatment strategy. ..
  20. Vaidyanathan U, Nelson L, Patrick C. Clarifying domains of internalizing psychopathology using neurophysiology. Psychol Med. 2012;42:447-59 pubmed publisher
    ..Notably, these indicators exhibit more specificity in their relations with these three domains than has been seen in quantitative-dimensional models. Implications of these findings are discussed. ..
  21. Rossi P, Vollono C, Valeriani M, Sandrini G. The contribution of clinical neurophysiology to the comprehension of the tension-type headache mechanisms. Clin Neurophysiol. 2011;122:1075-85 pubmed publisher
    ..On the other hand, clinical neurophysiology has played an important role in the debate about the pathogenesis of TTH...
  22. Hallett M, Rothwell J. Milestones in clinical neurophysiology. Mov Disord. 2011;26:958-67 pubmed publisher
    Over the last 25 years, clinical neurophysiology has made many advances in the understanding, diagnosis, and even treatment of different movement disorders. Transcranial magnetic stimulation has been the biggest technical advance...
  23. Clarke C, Ryan C, Martin D. Pain neurophysiology education for the management of individuals with chronic low back pain: systematic review and meta-analysis. Man Ther. 2011;16:544-9 pubmed publisher
    Pain neurophysiology education (PNE) is a form of education for patients with chronic low back pain (CLBP). The purpose of this systematic review was to investigate the evidence for PNE in the management of pateints with CLBP...
  24. Garcia Larrea L. Objective pain diagnostics: clinical neurophysiology. Neurophysiol Clin. 2012;42:187-97 pubmed publisher
  25. Roy S, Wang X. Wireless multi-channel single unit recording in freely moving and vocalizing primates. J Neurosci Methods. 2012;203:28-40 pubmed publisher
    ..Traditional neurophysiology techniques, however, require the animal to be restrained which often restricts natural behavior...
  26. Pro S, Tarantino S, Capuano A, Vigevano F, Valeriani M. Primary headache pathophysiology in children: the contribution of clinical neurophysiology. Clin Neurophysiol. 2014;125:6-12 pubmed publisher
    ..Moreover, the technique of transcranial magnetic stimulation, not yet used in young migraineurs, will possibly provide further elements about brain excitability in migraine children. ..
  27. Moseley G, Nicholas M, Hodges P. A randomized controlled trial of intensive neurophysiology education in chronic low back pain. Clin J Pain. 2004;20:324-30 pubmed
    ..However, it is not known whether the neurophysiology education component of such programs contributes to these outcomes...
  28. Mano T, Iwase S, Toma S. Microneurography as a tool in clinical neurophysiology to investigate peripheral neural traffic in humans. Clin Neurophysiol. 2006;117:2357-84 pubmed
    ..The present paper reviews how this technique has been used in clinical neurophysiology to elucidate the neural mechanisms of autonomic regulation, motor control and sensory functions in humans ..
  29. Nijs J, Van Houdenhove B. From acute musculoskeletal pain to chronic widespread pain and fibromyalgia: application of pain neurophysiology in manual therapy practice. Man Ther. 2009;14:3-12 pubmed publisher
    ..III) However, manual therapists ignoring the processes involved in the development and maintenance of chronic widespread pain/FM may cause more harm then benefit to the patient by triggering or sustaining central sensitisation. ..
  30. Litscher G. Bioengineering assessment of acupuncture, Part 6: monitoring--neurophysiology. Crit Rev Biomed Eng. 2007;35:1-36 pubmed
    ..g., 600 Hz oscillations). Although numerous questions concerning acupuncture remain still unsolved, the present findings could be a further step to discover the complex mechanisms underlying the effects of acupuncture. ..
  31. Merchant H, Georgopoulos A. Neurophysiology of perceptual and motor aspects of interception. J Neurophysiol. 2006;95:1-13 pubmed
    ..In this review, we discuss the wealth of knowledge that has accumulated on this topic with an emphasis on the results of neural studies in behaving monkeys. ..
  32. da Silva F. Contribution to a neurophysiology of consciousness. Suppl Clin Neurophysiol. 2004;57:645-55 pubmed
  33. Ronan L, Murphy K, Browne G, Connolly S, McMenamin J, Lynch B, et al. Needs analysis for tele-neurophysiology in the Irish North-Western Health Board. Ir Med J. 2004;97:46-9 pubmed
    No clinical neurophysiology (CN) service is currently provided by the North-Western Health Board (NWHB) region in Ireland...
  34. Tramo M, Cariani P, Koh C, Makris N, Braida L. Neurophysiology and neuroanatomy of pitch perception: auditory cortex. Ann N Y Acad Sci. 2005;1060:148-74 pubmed
    ..Studies motivated by interest in the neurophysiology and neuroanatomy of music perception have helped correct longstanding misconceptions about the functional ..
  35. Herz A, Meier R, Nawrot M, Schiegel W, Zito T. G-Node: an integrated tool-sharing platform to support cellular and systems neurophysiology in the age of global neuroinformatics. Neural Netw. 2008;21:1070-5 pubmed publisher
    ..Based on its technical and scientific scope, the Node could play a substantial role for cellular and systems neurophysiology as well as for the neuroscience community at large.
  36. Zele A, Vingrys A. Cathode-ray-tube monitor artefacts in neurophysiology. J Neurosci Methods. 2005;141:1-7 pubmed
    ..We suggest that a monitor frame rate >/=100 Hz provides a reasonable trade-off between refresh and the generators of high frequency noise. ..
  37. Zwarts M, Bleijenberg G, van Engelen B. Clinical neurophysiology of fatigue. Clin Neurophysiol. 2008;119:2-10 pubmed
    ..The present report discusses the different manifestations of fatigue and the available tools to assess peripheral and central fatigue. ..
  38. Fell J. Cognitive neurophysiology: beyond averaging. Neuroimage. 2007;37:1069-72 pubmed
    ..Therefore, separation of amplitude and phase contributions is indispensable to avoid misinterpretations and to gain a deeper understanding of the relation between event-related EEG and fMRI. ..
  39. Misiaszek J. The H-reflex as a tool in neurophysiology: its limitations and uses in understanding nervous system function. Muscle Nerve. 2003;28:144-60 pubmed
    ..The second part of this review explores the utility of the H-reflex as a neural probe in neurophysiology and motor control research...
  40. Taylor M, Swant J, Wagner J, Fisher J, Ferguson D. Lower thyroid compensatory reserve of rat pups after maternal hypothyroidism: correlation of thyroid, hepatic, and cerebrocortical biomarkers with hippocampal neurophysiology. Endocrinology. 2008;149:3521-30 pubmed publisher
    ..In summary, during depletion of serum T(4), D2 activity served as a sensitive marker of tissue thyroid status, an indicator of the brain's compensatory response to maintain cT(3), and correlated with a neurophysiological outcome. ..
  41. Hughes J. A review of sleepwalking (somnambulism): the enigma of neurophysiology and polysomnography with differential diagnosis of complex partial seizures. Epilepsy Behav. 2007;11:483-91 pubmed
    ..Associated disorders are Tourette's syndrome, sleep-disordered breathing, and migraine. Various kinds of treatment are discussed, as are legal considerations, especially murder during sleepwalking...
  42. Nakahara K, Adachi Y, Osada T, Miyashita Y. Exploring the neural basis of cognition: multi-modal links between human fMRI and macaque neurophysiology. Trends Cogn Sci. 2007;11:84-92 pubmed
    ..These approaches would illuminate the neurophysiological underpinnings of human cognitive functions by integrating human functional neuroimaging with macaque single-unit recordings. ..
  43. Krontiris Litowitz J. Using manipulatives to improve learning in the undergraduate neurophysiology curriculum. Adv Physiol Educ. 2003;27:109-19 pubmed
    ..This project examines the use of manipulatives in a neurophysiology curriculum and assesses their effectiveness on student comprehension...
  44. Gibson S, Farrell M. A review of age differences in the neurophysiology of nociception and the perceptual experience of pain. Clin J Pain. 2004;20:227-39 pubmed
    ..The clinical implications are obvious; older persons are likely to be especially vulnerable to the negative impacts of pain and pain associated events. ..
  45. Praamstra P, Seiss E. The neurophysiology of response competition: motor cortex activation and inhibition following subliminal response priming. J Cogn Neurosci. 2005;17:483-93 pubmed
    ..These results elucidate how response conflict causes interference as well as the conditions under which frontal-lobe-based interference control processes are engaged. ..
  46. Nijhawan R. Visual prediction: psychophysics and neurophysiology of compensation for time delays. Behav Brain Sci. 2008;31:179-98; discussion 198-239 pubmed publisher
    ..Understanding visual prediction will inform our theories of sensory processes and visual perception, and will impact our notion of visual awareness. ..
  47. Panzeri S, Senatore R, Montemurro M, Petersen R. Correcting for the sampling bias problem in spike train information measures. J Neurophysiol. 2007;98:1064-72 pubmed
    ..This provides information estimates with acceptable variance and which are unbiased even when the number of trials per stimulus is as small as the number of possible discrete neuronal responses. ..
  48. Li G, Jackson M, MacDonald J. Weighted least squares fitting with multiple templates for detection of small spontaneous signals. J Neurosci Methods. 2007;164:139-48 pubmed
    ..An important outcome of the weighted template technique is that the detection rate is not as sensitive to the length of templates and this technique is capable of detection overlapping events reliably. ..
  49. Fitzsimons M, Ronan L, Murphy K, Browne G, Connolly S, McMenamin J, et al. Customer needs, expectations, and satisfaction with clinical neurophysiology services in Ireland: a case for tele-neurophysiology development. Ir Med J. 2004;97:208-11 pubmed
    ..Development of tele-medicine services can improve equity of access. The specialty of Clinical Neurophysiology (CN), currently under-developed in Ireland provides an example of such potential...
  50. Gifford G, MacLean K, Hauser M, Cohen Y. The neurophysiology of functionally meaningful categories: macaque ventrolateral prefrontal cortex plays a critical role in spontaneous categorization of species-specific vocalizations. J Cogn Neurosci. 2005;17:1471-82 pubmed
  51. Padua L, Pazzaglia C, Caliandro P, Granata G, Foschini M, Briani C, et al. Carpal tunnel syndrome: ultrasound, neurophysiology, clinical and patient-oriented assessment. Clin Neurophysiol. 2008;119:2064-9 pubmed publisher
    ..Second, to assess the sensitivity of ultrasonography (US) and neurophysiology in the diagnosis of CTS using clinical measures as gold standard...
  52. Hauk O, Shtyrov Y, Pulvermuller F. The time course of action and action-word comprehension in the human brain as revealed by neurophysiology. J Physiol Paris. 2008;102:50-8 pubmed publisher
    ..The findings will be discussed in the general context of putative brain mechanisms of word and object recognition. ..
  53. Rowe D, Hermens D. Attention-deficit/hyperactivity disorder: neurophysiology, information processing, arousal and drug development. Expert Rev Neurother. 2006;6:1721-34 pubmed
    ..The clinical implications for a cholinergic hypothesis of ADHD are considered, along with its possible implications for treatment and pharmacological development. ..