Summary: The branch of science concerned with the means and consequences of transmission and generation of the components of biological inheritance. (Stedman, 26th ed)

Top Publications

  1. Smith M, Wood W, Knight J. The Genetics Concept Assessment: a new concept inventory for gauging student understanding of genetics. CBE Life Sci Educ. 2008;7:422-30 pubmed publisher
    We have designed, developed, and validated a 25-question Genetics Concept Assessment (GCA) to test achievement of nine broad learning goals in majors and nonmajors undergraduate genetics courses...
  2. Condit C. Public attitudes and beliefs about genetics. Annu Rev Genomics Hum Genet. 2010;11:339-59 pubmed publisher
    The existing research base on public attitudes about genetics shows that people's attitudes vary according to the specific technologies and purposes to which genetic knowledge is applied...
  3. McCluskey K, Wiest A, Plamann M. The Fungal Genetics Stock Center: a repository for 50 years of fungal genetics research. J Biosci. 2010;35:119-26 pubmed
    The Fungal Genetics Stock Center (FGSC) was established in 1960 to ensure that important strains used in early genetics research were available to subsequent generations of fungal geneticists. Originally, only mutant strains were held...
  4. Heard E, TISHKOFF S, Todd J, Vidal M, Wagner G, Wang J, et al. Ten years of genetics and genomics: what have we achieved and where are we heading?. Nat Rev Genet. 2010;11:723-33 pubmed publisher
    To celebrate the first 10 years of Nature Reviews Genetics, we asked eight leading researchers for their views on the key developments in genetics and genomics in the past decade and the prospects for the future...
  5. Gliboff S. Did Paul Kammerer discover epigenetic inheritance? No and why not. J Exp Zool B Mol Dev Evol. 2010;314:616-24 pubmed publisher
  6. Helder S, Collier D. The genetics of eating disorders. Curr Top Behav Neurosci. 2011;6:157-75 pubmed publisher
    ..More recently, with the advent of genome-wide association studies (GWAS), analysis with microsatellite markers has implicated novel candidate loci for AN at 1q41 and 11q22, and further GWAS results are expected in the near future. ..
  7. Guillemaud T, Ciosi M, Lombaert E, Estoup A. Biological invasions in agricultural settings: insights from evolutionary biology and population genetics. C R Biol. 2011;334:237-46 pubmed publisher
    ..In this article we suggest that the reconstruction of invasion routes with population genetics-based methods can address fundamental questions in ecology and practical aspects of the management of biological ..
  8. Edwards K, Lemke A, Trinidad S, Lewis S, Starks H, Quinn Griffin M, et al. Attitudes toward genetic research review: results from a survey of human genetics researchers. Public Health Genomics. 2011;14:337-45 pubmed publisher
    ..The results from this study provide important perspectives of researchers regarding genetic research review and show lack of consensus on key research ethics issues in genomic research. ..
  9. Lindblom A, Robinson P. Bioinformatics for human genetics: promises and challenges. Hum Mutat. 2011;32:495-500 pubmed publisher (IT) systems and electronic health records, amass ever-increasing amounts of data before human genetics scientists and clinicians...

More Information


  1. Grant D, Nelson R, Cannon S, Shoemaker R. SoyBase, the USDA-ARS soybean genetics and genomics database. Nucleic Acids Res. 2010;38:D843-6 pubmed publisher
    SoyBase, the USDA-ARS soybean genetic database, is a comprehensive repository for professionally curated genetics, genomics and related data resources for soybean...
  2. Calzone K, Jenkins J, Prows C, Masny A. Establishing the outcome indicators for the essential nursing competencies and curricula guidelines for genetics and genomics. J Prof Nurs. 2011;27:179-91 pubmed publisher
    The translation of genetics/genomics to clinical care has implications for nurses. The Essential Nursing Competencies and Curricula Guidelines for Genetics and Genomics, established by consensus, apply to all registered nurses...
  3. Matzuk M, Burns K. Genetics of mammalian reproduction: modeling the end of the germline. Annu Rev Physiol. 2012;74:503-28 pubmed publisher
    ..Finally, we reflect on the future of reproductive biology: how advances in clinical genetics will provide special opportunities to understand which reproductive processes are affected by genetic lesions and ..
  4. Tairyan K, Illes J. Imaging genetics and the power of combined technologies: a perspective from neuroethics. Neuroscience. 2009;164:7-15 pubmed publisher
    Imaging genetics has emerged as a powerful and sensitive approach to the study of functional genetic variations and brain responses in psychiatric and neurologic disorders...
  5. Sawcer S, Wason J. Risk in complex genetics: "all models are wrong but some are useful". Ann Neurol. 2012;72:502-9 pubmed publisher
  6. Caburnay C, Babb P, Kaphingst K, Roberts J, Rath S. Characteristics of genetics-related news content in Black weekly newspapers. Public Health Genomics. 2014;17:7-15 pubmed publisher
    ..This study characterized media coverage of genetics-related information in Black weekly newspapers and general audience newspapers from the same communities...
  7. Gieger C, Geistlinger L, Altmaier E, Hrabe de Angelis M, Kronenberg F, Meitinger T, et al. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet. 2008;4:e1000282 pubmed publisher
    ..These genetically determined metabotypes may subscribe the risk for a certain medical phenotype, the response to a given drug treatment, or the reaction to a nutritional intervention or environmental challenge. ..
  8. Siritunga D, Montero Rojas M, Carrero K, Toro G, Velez A, Carrero Martinez F. Culturally relevant inquiry-based laboratory module implementations in upper-division genetics and cell biology teaching laboratories. CBE Life Sci Educ. 2011;10:287-97 pubmed publisher
    ..Laboratory modules were implemented in upper-division genetics and cell biology courses using cassava as the central theme...
  9. Colon Berlingeri M, Burrowes P. Teaching biology through statistics: application of statistical methods in genetics and zoology courses. CBE Life Sci Educ. 2011;10:259-67 pubmed publisher
    ..prerequisites to core science courses, and incorporating interdisciplinary (math-biology) learning activities in genetics and zoology courses...
  10. Bevilacqua L, Goldman D. Genetics of emotion. Trends Cogn Sci. 2011;15:401-8 pubmed publisher
    ..The effects of these genes can be validated by neuroimaging, neuroendocrine and other studies accessing intermediate phenotypes, deepening our understanding of mechanisms of emotion and variation in emotionality. ..
  11. Meyer Lindenberg A. The future of fMRI and genetics research. Neuroimage. 2012;62:1286-92 pubmed publisher
    I provide a brief and subjective view of where the field of imaging genetics is heading...
  12. O DANIEL J, Haga S. Public perspectives on returning genetics and genomics research results. Public Health Genomics. 2011;14:346-55 pubmed publisher
    ..Although there was general interest in obtaining genetics research results, particularly individual results, discussants recognized many potential complexities...
  13. Chaput J, Yu H, Zhang S. The emerging world of synthetic genetics. Chem Biol. 2012;19:1360-71 pubmed publisher
    ..This area of synthetic biology, commonly referred to as in vitro genetics, is made possible by the availability of natural polymerases that can replicate genetic information in the ..
  14. Houwink E, van Luijk S, Henneman L, van der Vleuten C, Jan Dinant G, Cornel M. Genetic educational needs and the role of genetics in primary care: a focus group study with multiple perspectives. BMC Fam Pract. 2011;12:5 pubmed publisher
    Available evidence suggests that improvements in genetics education are needed to prepare primary care providers for the impact of ongoing rapid advances in genomics...
  15. Short S, Yang Y, Jenkins T. Sex, gender, genetics, and health. Am J Public Health. 2013;103 Suppl 1:S93-101 pubmed publisher
    This article addresses 2 questions. First, to what extent are sex and gender incorporated into research on genetics and health? Second, how might social science understandings of sex and gender, and gender differences in health, become ..
  16. Hendry A. Key questions in the genetics and genomics of eco-evolutionary dynamics. Heredity (Edinb). 2013;111:456-66 pubmed publisher
    ..The genetics and genomics of these 'eco-evolutionary dynamics' will be--to a large extent--the genetics and genomics of ..
  17. Nelson R, Pettersson M, Carlborg O. A century after Fisher: time for a new paradigm in quantitative genetics. Trends Genet. 2013;29:669-76 pubmed publisher
    Quantitative genetics traces its roots back through more than a century of theory, largely formed in the absence of directly observable genotype data, and has remained essentially unchanged for decades...
  18. Smith M, Wood W, Adams W, Wieman C, Knight J, Guild N, et al. Why peer discussion improves student performance on in-class concept questions. Science. 2009;323:122-4 pubmed publisher
    ..To distinguish between these alternatives in an undergraduate genetics course, we followed the above exercise with a second, similar (isomorphic) question on the same concept that ..
  19. Schughart K. SYSGENET: a meeting report from a new European network for systems genetics. Mamm Genome. 2010;21:331-6 pubmed publisher
    ..About 50 researchers working in the field of systems genetics using mouse genetic reference populations (GRP) participated in the meeting and exchanged their results, ..
  20. D Costa A, Shepherd I. Zebrafish development and genetics: introducing undergraduates to developmental biology and genetics in a large introductory laboratory class. Zebrafish. 2009;6:169-77 pubmed publisher
    We have taken advantage of the strengths of the zebrafish model system to introduce developmental biology and genetics to undergraduates in their second semester of the Introductory Biology course at Emory...
  21. Coghill D, Banaschewski T. The genetics of attention-deficit/hyperactivity disorder. Expert Rev Neurother. 2009;9:1547-65 pubmed publisher
    ..While molecular genetic approaches have identified a range of potential candidate genes, it is now clear that the genetics of ADHD are characterized by a number of genes each of which makes a small but significant contribution to the ..
  22. Stover P, Harlan W, Hammond J, Hendershot T, Hamilton C. PhenX: a toolkit for interdisciplinary genetics research. Curr Opin Lipidol. 2010;21:136-40 pubmed publisher
    ..disease research and to demonstrate how these and other PhenX measures can be used to further interdisciplinary genetics research...
  23. Valdmanis P, Daoud H, Dion P, Rouleau G. Recent advances in the genetics of amyotrophic lateral sclerosis. Curr Neurol Neurosci Rep. 2009;9:198-205 pubmed
    ..The findings help to better delineate the types of genes and genetic variants that are involved in ALS and provide substantial material for future research. ..
  24. Gelernter J, Kranzler H. Genetics of drug dependence. Dialogues Clin Neurosci. 2010;12:77-84 pubmed
    ..Although considerable progress has been made, it is likely that the application of more extensive sequencing than has previously been practical will be required to identify a fuller range of risk variants. ..
  25. Burke S, Martyn M, Thomas H, Farndon P. The development of core learning outcomes relevant to clinical practice: identifying priority areas for genetics education for non-genetics specialist registrars. Clin Med (Lond). 2009;9:49-52 pubmed
    Advances in medical genetics are increasingly impacting on clinical practice outside specialist genetic services...
  26. Aerts S, Vilain S, Hu S, Tranchevent L, Barriot R, Yan J, et al. Integrating computational biology and forward genetics in Drosophila. PLoS Genet. 2009;5:e1000351 pubmed publisher
    ..However, a systems biology approach to genetics must leverage the massive amount of "omics" data to enhance the power and speed of functional gene ..
  27. Burton H, Alberg C, Stewart A. Mainstreaming genetics: a comparative review of clinical services for inherited cardiovascular conditions in the UK. Public Health Genomics. 2010;13:235-45 pubmed publisher
    ..Services should be led by cardiology but have close links with clinical genetics services, which should provide support with specialist genetics advice and cascade testing...
  28. Laberge A, Fryer Edwards K, Kyler P, Lloyd Puryear M, Burke W. Long-term outcomes of the "Genetics in Primary Care" faculty development initiative. Fam Med. 2009;41:266-70 pubmed
    Between October 2000 and April 2001, 79 primary care physicians (PCPs) and 21 genetics professionals from 20 teaching medical universities across the United States participated in the Genetics in Primary Care (GPC) project (a national ..
  29. Greenwald I. Notch and the awesome power of genetics. Genetics. 2012;191:655-69 pubmed publisher
    ..As an essay for the GENETICS Perspectives series, it is my personal and critical commentary as well as an historical account of discovery.
  30. Skirton H, O Connor A, Humphreys A. Nurses' competence in genetics: a mixed method systematic review. J Adv Nurs. 2012;68:2387-98 pubmed publisher
    To ascertain the extent to which nurses are achieving the core competences in genetics appropriate for nursing practice. ? There is an increasing focus on genetics in nursing, and relevant core competences have been developed...
  31. Pennell M, Harmon L. An integrative view of phylogenetic comparative methods: connections to population genetics, community ecology, and paleobiology. Ann N Y Acad Sci. 2013;1289:90-105 pubmed publisher
    ..across fields and focus on three examples where such integration might be particularly valuable: quantitative genetics, community ecology, and paleobiology...
  32. Fridman E, Zamir D. Next-generation education in crop genetics. Curr Opin Plant Biol. 2012;15:218-23 pubmed publisher
    ..We discuss the need, opportunities and conflicts associated with revamping plant breeding teaching programs to bridge the art and science of this profession with a rapidly expanding job market. ..
  33. Smith M, Knight J. Using the Genetics Concept Assessment to document persistent conceptual difficulties in undergraduate genetics courses. Genetics. 2012;191:21-32 pubmed publisher
    To help genetics instructors become aware of fundamental concepts that are persistently difficult for students, we have analyzed the evolution of student responses to multiple-choice questions from the Genetics Concept Assessment...
  34. Franke B, Faraone S, Asherson P, Buitelaar J, Bau C, Ramos Quiroga J, et al. The genetics of attention deficit/hyperactivity disorder in adults, a review. Mol Psychiatry. 2012;17:960-87 pubmed publisher
    ..Progress in identifying aADHD risk genes may provide us with tools for the prediction of disease progression in the clinic and better treatment, and ultimately may help to prevent persistence of ADHD into adulthood. ..
  35. Dougherty M. Closing the gap: inverting the genetics curriculum to ensure an informed public. Am J Hum Genet. 2009;85:6-12 pubmed publisher
    ..This underperformance is true for genetics, as well as for science and math in general, and is particularly worrisome given the accelerating need for ..
  36. Curran C, Park R, Ho S, Haynes E. Incorporating genetics and genomics in risk assessment for inhaled manganese: from data to policy. Neurotoxicology. 2009;30:754-60 pubmed publisher
    ..The difficulties involved in moving from epidemiological and in vivo data to health-based quantitative risk assessment and ultimately enforceable government standards are discussed. ..
  37. Vargas A. Did Paul Kammerer discover epigenetic inheritance? A modern look at the controversial midwife toad experiments. J Exp Zool B Mol Dev Evol. 2009;312:667-78 pubmed publisher
    ..Given available molecular tools and our current understanding of epigenetics, new experimentation with the midwife toad is strongly encouraged. ..
  38. Allendorf F, HOHENLOHE P, Luikart G. Genomics and the future of conservation genetics. Nat Rev Genet. 2010;11:697-709 pubmed publisher
    ..Now is a crucial time to explore the potential implications of this information revolution for conservation genetics and to recognize limitations in applying genomic tools to conservation issues...
  39. Chiang M, McMahon K, de Zubicaray G, Martin N, Hickie I, Toga A, et al. Genetics of white matter development: a DTI study of 705 twins and their siblings aged 12 to 29. Neuroimage. 2011;54:2308-17 pubmed publisher
    ..Genes affect fiber integrity, but their effects vary with age, sex, SES and IQ. Gene-environment interactions are vital to consider in the search for specific genetic polymorphisms that affect brain integrity and connectivity. ..
  40. Kriegebaum C, Gutknecht L, Schmitt A, Lesch K, Reif A. [Serotonin now: Part 1. Neurobiology and developmental genetics]. Fortschr Neurol Psychiatr. 2010;78:319-31 pubmed publisher
  41. Knight J, Smith M. Different but equal? How nonmajors and majors approach and learn genetics. CBE Life Sci Educ. 2010;9:34-44 pubmed publisher
    ..To assess the evidence behind this assumption, we compared students in two different genetics classes at the University of Colorado-Boulder, one class for nonscience majors (nonmajors) and the other class ..
  42. Condit C. Public understandings of genetics and health. Clin Genet. 2010;77:1-9 pubmed publisher
    This review of adult public understandings of genetics related to health indicates that the public's understandings overlap with those of professionals in some areas, but not others...
  43. Charlesworth B, Charlesworth D. Darwin and genetics. Genetics. 2009;183:757-66 pubmed publisher
    ..We review the interaction between evolution and genetics, showing how, unlike Mendel, Darwin's lack of a model of the mechanism of inheritance left him unable to ..
  44. Miller F, Hayeems R, Li L, Bytautas J. What does 'respect for persons' require? Attitudes and reported practices of genetics researchers in informing research participants about research. J Med Ethics. 2012;38:48-52 pubmed publisher
    ..Results of an international survey of 785 eligible authors of genetics research studies in autism or cystic fibrosis are reported...
  45. Garrett J, Triman K. Resources and strategies to integrate the study of ethical, legal, and social implications of genetics into the undergraduate curriculum. Adv Genet. 2009;66:35-59 pubmed publisher individual's genetic information are just a few of the developments emerging from recent advances in molecular genetics that are controversial...
  46. Møller P, Clark N. CGEN--a Clinical GENetics software application. Hum Mutat. 2011;32:537-42 pubmed publisher
    CGEN (Clinical GENetics) is a software application built to manage the IT requirements of genetic clinics with the specific focus to collect well-organized and verified data for genetic research...
  47. Dhar S, Alford R, Nelson E, Potocki L. Enhancing exposure to genetics and genomics through an innovative medical school curriculum. Genet Med. 2012;14:163-7 pubmed publisher
    Physicians entering medical practice in the 21st century will require more than a basic understanding of human genetics because of rapid progress in the field of genetics and genomics...
  48. Tiwari A, Zai C, Muller D, Kennedy J. Genetics in schizophrenia: where are we and what next?. Dialogues Clin Neurosci. 2010;12:289-303 pubmed
    ..In this review we summarize the major findings of the past decade and suggest areas of future research. ..
  49. Etchegary H, Green J, Dicks E, Pullman D, Street C, Parfrey P. Consulting the community: public expectations and attitudes about genetics research. Eur J Hum Genet. 2013;21:1338-43 pubmed publisher
    ..a public information-consultation session in order to explore public awareness, perception and expectations about genetics and genomics research...
  50. Gold E, Carbone J. Myriad Genetics: In the eye of the policy storm. Genet Med. 2010;12:S39-70 pubmed publisher
    ..Myriad Genetics, Inc., along with its subsidiary, Myriad Genetic Laboratories, Inc...
  51. Burke S, Martyn M, Stone A, Bennett C, Thomas H, Farndon P. Developing a curriculum statement based on clinical practice: genetics in primary care. Br J Gen Pract. 2009;59:99-103 pubmed publisher
    Advances in medical genetics are increasingly being incorporated into clinical management outside specialist genetic services...
  52. Dougherty M, Pleasants C, Solow L, Wong A, Zhang H. A comprehensive analysis of high school genetics standards: are states keeping pace with modern genetics?. CBE Life Sci Educ. 2011;10:318-27 pubmed publisher teaching and learning, we investigated the quality of life sciences/biology standards with respect to genetics for all 50 states and the District of Columbia, using core concepts developed by the American Society of Human ..
  53. Wolf J, Lindell J, Backstrom N. Speciation genetics: current status and evolving approaches. Philos Trans R Soc Lond B Biol Sci. 2010;365:1717-33 pubmed publisher
    ..This review aims at providing an extensive overview of speciation genetics. Starting from key historical developments and core concepts of speciation genetics, we focus much of our ..